TNF Alpha Inhibitors Market Expected to Grow by 3.6% During the Forecast Period, 2019-2025 – P&T Community

DUBLIN, Oct. 11, 2019 /PRNewswire/ -- The "TNF Alpha Inhibitors Market By Drug Class (Adalimumab, Certolizumab Pegol, Etanercept, Golimumab, Infliximab), By Pipeline Analysis (Phase I, Phase II, Phase III), By Regions - Global Forecast up to 2025" report has been added to ResearchAndMarkets.com's offering.

Overview of the Global TNF Alpha Inhibitors Market Research:

The author's market research report predicts that the global TNF alpha inhibitors market will grow at a CAGR of 3.6% during the forecast period 2019-2025.

TNF inhibitors, also known as TNF blockers, anti-TNF drugs, and biologic therapies, are a cluster of medications used to treat inflammatory conditions, including rheumatoid arthritis, juvenile arthritis, psoriatic arthritis, ankylosing spondylitis, inflammatory bowel disease (Crohn's and ulcerative colitis), and psoriasis. The drugs decrease inflammation and can stop disease development by targeting an inflammation-causing substance, tumor necrosis factor (TNF).

The market is witnessing the loss of patents in Europe for various blockbuster drugs, resulting in the emergence of biosimilars. In April 2019, Eticovo - a biosimilar from Samsung Bioepis to Amgen's Enbrel (etanercept), received FDA approval. In November 2018, FDA approved Hyrimoz developed by Sandoz, a biosimilar to AbbVie's blockbuster drug Humira, which will be launched in the US market by 2023. Currently, only five approved TNF inhibitors, i.e., adalimumab, certolizumab, etanercept, golimumab, and infliximab, control the market. The wide application of these drugs for numerous autoimmune diseases ensures constant growth of the market during the forecast period 2019-2025.

According to the author analysis, North America accounted for the largest share of the global TNF alpha inhibitors market in 2018 and will retain a high position during the forecast period. North America is followed by Europe, with a market share of more than 20% in 2018.

In 2018, the adalimumab segment accounted for the largest share and is expected to grow at a mid-single-digit CAGR during the forecast period. Increased clinical efficacy and high preference by physicians for the treatment of severe rheumatic diseases made the segment the largest shareholder in 2018. Golimumab is expected to grow at a high CAGR during the forecast period 2019-2025.

Many companies are making huge investments to develop products and enter the market as soon as biologics lose their patents. Among various TNF alpha inhibitors, adalimumab has the highest number of ongoing clinical trials, followed by certolizumab pegol.

Global TNF Alpha Inhibitors Market Research Competitive Analysis: The market is growing at a steady rate, i.e., at a CAGR of 3.6% during the forecast period 2019-2025. New drug launches, product approvals, strategic partnerships, and collaborations are among the significant strategies adopted by market leaders to maintain their leadership position. For instance, in July 2019, the US FDA approved HADLIMA by Samsung Bioepis, a biosimilar referencing HUMIRA, to treat juvenile idiopathic arthritis, adult Crohn's disease, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, rheumatoid arthritis, and plaque psoriasis. In March 2019, the US FDA approved Cimzia injection to treat non-radiographic axial spondyloarthritis (nr-axSpA) in adults, with detached signs of swelling making it the first-ever FDA approved treatment fulfilling the unmet needs for nr-axSpA; and in May 2018, the drug was approved for the treatment of moderate-to-severe plaque psoriasis.

The rising incidence of chronic autoimmune diseases has led to the increasing launch of biosimilars globally. In May 2019, Fresenius Kabi launched biosimilar adalimumab IDACIO in Germany. In May 2019, Janssen launched Simponi Autoinjector in Japan, and the drugs are distributed by Mitsubishi Tanabe. In addition, other leading vendors are focusing on hugely investing in R&D activities to develop new drugs to obtain a high share in the market.

Key Competitive Facts:

Key Topics Covered:

1 Industry Outlook1.1 Industry Overview 1.1.1 Global Driver for Pharmaceutical Demand 1.1.2 R&D Pipeline in Pharmaceutical Industry 1.1.3 Top Pharma Drugs by Sales ($Million) 1.2 Industry Trends 1.3 Total Addressable Market 1.4 Trends of the Immunotherapy Drugs Market

2 Report Outline2.1 Report Scope 2.2 Report Summary 2.3 Research Methodology 2.4 Report Assumptions

3 Market Snapshot3.1 Market Definition - Infoholic Research 3.2 Segmented Addressable Market (SAM) 3.3 Trends of the TNF Alpha Inhibitors Market 3.4 Related Markets 3.4.1 Oncology Drugs 3.4.2 Biologics 3.4.3 Biosimilars

4 Market Outlook4.1 Market Segmentation 4.2 PEST Analysis 4.3 Porter 5(Five) Forces

5 Market Characteristics5.1 DRO - Global TNF Alpha Inhibitors Market Dynamics 5.1.1 Drivers 5.1.1.1 Increasing prevalence of chronic autoimmune disease 5.1.1.2 Constant research to develop target-based biologics 5.1.2 Opportunities 5.1.2.1 Continuous development of biosimilars 5.1.2.2 Increasing opportunities in the emerging market 5.1.3 Restraints 5.1.3.1 Complex drug development process 5.1.3.2 Patent expiry 5.2 DRO - Impact Analysis 5.3 Key Stakeholders

6 Product: Market Size and Analysis6.1 Overview 6.2 Adalimumab 6.3 Certolizumab Pegol 6.4 Etanercept 6.5 Golimumab 6.6 Infliximab

7 Pipeline Analysis: Market Size and Analysis7.1 Overview 7.2 Phase I 7.3 Phase II 7.4 Phase III

8 Regions: Market Size and Analysis8.1 Overview 8.2 North America 8.3 Europe 8.4 Asia Pacific 8.5 Rest of the World 8.5.2 Mexico 8.5.3 Brazil 8.5.4 Middle East and Africa

9 Competitive Landscape

10 Vendors Profile10.1 AbbVie Inc. 10.1.1 Overview 10.1.2 Geographic Revenue 10.1.3 Business Focus 10.1.4 SWOT Analysis 10.1.5 Business Strategies 10.2 Novartis AG 10.3 Amgen Inc. 10.4 Johnson & Johnson 10.5 Celgene Corporation

11 Companies to Watch For11.1 Apogenix 11.1.1 Overview 11.2 Celltrion Healthcare 11.3 Samsung Bioepis Co. Ltd. 11.4 3SBio Inc. 11.5 Shanghai CP Guojian Pharmaceutical Co. Ltd.

For more information about this report visit https://www.researchandmarkets.com/r/cl7qzh

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TNF Alpha Inhibitors Market Expected to Grow by 3.6% During the Forecast Period, 2019-2025 - P&T Community