Itchy Japan first to approve Novartis psoriasis drug

GENEVA Swiss pharmaceutical giant Novartis said Friday it has won approval to market its Cosentyx psoriasis treatment in Japan, making it the first country to authorize commercialization of the drug.

The Japanese decision allows Novartis to sell secukinumab, sold under the name Cosentyx, to adult patients suffering psoriasis vulgaris and psoriatic arthritis, and who arent responding to other medication.

The drug is considered by experts to have potentially enormous market value of between $1 billion and $2.5 billion annually. Its estimated 3 percent of the worlds population or over 125 million people suffer from some form of psoriasis, including over 400,000 in Japan alone.

Psoriasis vulgaris is a skin disease provoking thick, itchy lesions, while the articular variant causes stiffness and pain in joints.

Novartis said in a statement that during clinical testing of the drug, 70 percent of patients experienced improvement or complete clearing of their psoriasis symptoms.

Approval in Japan follows the recommendation by European drug regulators in November that Cosentyx be approved for sale as a first-line treatment for psoriasis.

Similarly, the U.S. Food and Drug Administration is expected to approve the medication in early 2015 after its panel issued a similarly positive recommendation in October.

Novartis says Cosentyx is a human monoclonal antibody that neutralizes a protein that is present in highly concentrated levels in psoriasis patients.

Read the original post:
Itchy Japan first to approve Novartis psoriasis drug