PUBLIC RELEASE DATE:
6-Mar-2014
Contact: Jia Liu liujia@genomics.cn BGI Shenzhen
Shenzhen, February 27, 2014 - Researchers from Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, BGI, University of Copenhagen and other institutes have successfully cracked the genome of high oil content crop sesame, providing new lights on the important stages of seed development and oil accumulation, and potential key genes for sesamin production. The joint efforts made sesame become the second Lamiales to be sequenced along with the former published minute genome of Utricularia gibba. The latest study was published online in Genome Biology.
Sesame, Sesamum indicum L., is considered as the queen of oilseeds for its high oil content and quality. It is grown widely in tropical and subtropical areas as an important source of oil and protein. Compared to other eatable oil crops such as soybean, rapeseed, peanut and olive, sesame has innate superiority for its high oil content (~55% of dry seed), and thus is an attractive model for studying lipid biosynthesis. However, currently only limited genomic data of sesame is available.
In this study, researchers presented a high-quality draft genome of the sesame genotype 'Zhongzhi No. 13', an elite cultivar in China been planted over the past ten years. After data process, the assembled sesame genome size is about 337 Mb, with a total of 27,148 genes. The result highlighted the absence of the Toll/interleukin-1 receptor domain in resistance genes, and suggested that this may be a new paradigm in elucidating the interaction of resistance genes along with diseases.
To explore the molecular mechanism of lipid biosynthesis, researchers conducted comparative genomic and transcriptomic analyses and found an expansion on type 1 lipid transfer genes by tandem duplication, a contraction on lipid degradation genes, and the differential expression of essential genes in the triacylglycerol biosynthesis pathway, particularly in the early stage of seed development. Researchers further resequenced 29 sesame accessions from 12 countries to investigate the genetic diversity of lipid-related genes.
Sesamin is an oil-soluble furofuran lignan typically present in sesame seed. Numerous studies on rats and mice have suggested various health benefits of sesamin. This compound is known to promote normalize blood pressure, lower cholesterol, protect the liver, and contribute to weight loss. Sesamin biosynthesis involves two key genes encoding dirigent protein (DIR) and piperitol/sesamin synthase (PSS), respectively. In this study, researchers found that DIR homologues were present in sesame and tomato, but the PSSs are only detected in sesame, indicating the genetic foundation for the sesame-specific product.
###
About BGI
Follow this link:
The genome of sesame sheds new lights on oil biosynthesis
- ENCODE: Encyclopedia Of DNA Elements - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- 07.05.2010 - The Human Genome [ Coast To Coast AM ] - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- NOVA scienceNOW : 51 - Public Genomes, Algae Fuel, Mystery of the Gakkel Ridge, Yoky Matsuoka - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Vincent T. - Genome (Club Remix) - [Preview] - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Comparing The Human And Chimpanzee Genomes - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Whole Genome Sequencing and Its Impact on Clinical Care - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Carlos Bustamante -- "Reconstructing the Great Human Diasporas from Genome Variation Data" - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- 3 Sad Surprises: The Human Genome Project - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- The RFW interviews Genome - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Science Bulletins: Scientists Peer Inside "Superbug" Genome - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Genome : Live @ Smu's : June 3 2012 - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Inoki Genome Federation - Genome 19 - 04 02 2012 - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- THE HUMAN GENOME MUSIC PROJECT - CHROMOSOME 1 - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Genomic Medicine - Bruce Korf (2012) - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Human Genome's 'Blockbuster' Potential Undervalued in Bid GSK vs HGSI - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Announcing the Completion of the First Survey of the Entire Human Genome at the White House - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- DNA analysis Part I. Genomic Sequencing - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- The Genome Question: Moore vs. Jevons with Bud Mishra - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Genome-Wide Association Studies - Karen Mohlke (2012) - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- New human genome research aids understanding of disease [Last Updated On: September 8th, 2012] [Originally Added On: September 8th, 2012]
- UNC Lineberger scientists lead definition of key lung cancer genome [Last Updated On: September 10th, 2012] [Originally Added On: September 10th, 2012]
- Illumina Announces Expedited Individual Genome Sequencing Service (IGS) [Last Updated On: September 11th, 2012] [Originally Added On: September 11th, 2012]
- Genome research given a boost with opening of bioscience facility [Last Updated On: September 11th, 2012] [Originally Added On: September 11th, 2012]
- Re-Imagining Our Genes: ENCODE Project Reveals Genome as an Information Processing System [Last Updated On: September 11th, 2012] [Originally Added On: September 11th, 2012]
- Illumina unveils upgraded genome sequence service [Last Updated On: September 12th, 2012] [Originally Added On: September 12th, 2012]
- US Personalized Cancer Genome Sequencing Market [Last Updated On: September 18th, 2012] [Originally Added On: September 18th, 2012]
- Yale maps “uncharted” genome regions [Last Updated On: September 18th, 2012] [Originally Added On: September 18th, 2012]
- Research and Markets: US Personalized Cancer Genome Sequencing Market [Last Updated On: September 19th, 2012] [Originally Added On: September 19th, 2012]
- 3Qs: New clues to unlocking the genome [Last Updated On: September 19th, 2012] [Originally Added On: September 19th, 2012]
- Oyster Genome Pries Open Mollusk Evolutionary Shell [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- Bangladeshi scientist decodes genome of deadly fungus [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- Oyster genome uncover the stress adaptation and complexity of shell formation [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- The oyster genome reveals stress adaptation and complexity of shell formation [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- Diseases of aging map to a few 'hotspots' on the human genome [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- GnuBIO Awarded $4.5 Million in Funding from the National Human Genome Research Institute to Develop Lower Cost Genome ... [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- Oyster genome mystery unravelled [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- Devangshu Datta: What's in a genome [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- Pacific Oyster Genome Shows Stress Adaptation And Complexity Of Shell Formation [Last Updated On: September 20th, 2012] [Originally Added On: September 20th, 2012]
- UNC Lineberger scientists lead cancer genome analysis of breast cancer [Last Updated On: September 24th, 2012] [Originally Added On: September 24th, 2012]
- Encoding the human genome [Last Updated On: September 24th, 2012] [Originally Added On: September 24th, 2012]
- Cancer genome analysis of breast cancer: Team identifies genetic causes and similarity to ovarian cancer [Last Updated On: September 24th, 2012] [Originally Added On: September 24th, 2012]
- Fungus genome map paves way for 'Snow White' jute variety [Last Updated On: September 24th, 2012] [Originally Added On: September 24th, 2012]
- New online, open access journal focuses on microbial genome announcements [Last Updated On: September 25th, 2012] [Originally Added On: September 25th, 2012]
- By Simply Sharing, Doctors Could Unlock the Genome's Potential [Last Updated On: September 25th, 2012] [Originally Added On: September 25th, 2012]
- Forget the Cloud—Knome Offers Genome Analysis in a Box [Last Updated On: September 28th, 2012] [Originally Added On: September 28th, 2012]
- BGI@CHOP Joint Genome Center to Offer Clinical Next-Generation Sequencing Services [Last Updated On: September 28th, 2012] [Originally Added On: September 28th, 2012]
- Holy Bat Virus! Genome Hints At Origin Of SARS-Like Virus [Last Updated On: September 29th, 2012] [Originally Added On: September 29th, 2012]
- Community Fundraising Effort Helps Researchers Sequence Parrot Genome [Last Updated On: September 29th, 2012] [Originally Added On: September 29th, 2012]
- UMass Med professors are sleuths of the genome [Last Updated On: September 30th, 2012] [Originally Added On: September 30th, 2012]
- Knome Introduces the knoSYS™100; First Plug-and-Play Human Genome Interpretation System [Last Updated On: September 30th, 2012] [Originally Added On: September 30th, 2012]
- First large scale trial of whole-genome cancer testing for clinical decision-making reported [Last Updated On: October 1st, 2012] [Originally Added On: October 1st, 2012]
- Should You Get Your Genome Mapped? [Last Updated On: October 1st, 2012] [Originally Added On: October 1st, 2012]
- Surprising differences between apples and pears [Last Updated On: October 2nd, 2012] [Originally Added On: October 2nd, 2012]
- 50-Hour Whole Genome Sequencing Provides Rapid Diagnosis for Children With Genetic Disorders [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- A map of rice genome variation reveals the origin of cultivated rice [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- Genome analysis promises hope for breast cancer patients [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- Genome Alberta Welcomes Alberta Minister of Enterprise and Advanced Education, Stephen Khan and Federal Minister of ... [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- Fifty-hour whole genome sequencing provides rapid diagnosis for children with genetic disorders [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- Will Low-Cost Genome Sequencing Open 'Pandora's Box'? [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- Genome testing could help individualize treatments [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- Would you get your genome tested? [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- The Genome — a Pandora's Box? [Last Updated On: October 4th, 2012] [Originally Added On: October 4th, 2012]
- Fast genome test could help sick newborns [Last Updated On: October 4th, 2012] [Originally Added On: October 4th, 2012]
- In-Depth Genome Analysis Moves Toward The Hospital Bed [Last Updated On: October 5th, 2012] [Originally Added On: October 5th, 2012]
- Your Verdict On Getting A Genome Test? Bring It On [Last Updated On: October 6th, 2012] [Originally Added On: October 6th, 2012]
- Genome-wide study identifies 8 new susceptibility loci for atopic dermatitis [Last Updated On: October 7th, 2012] [Originally Added On: October 7th, 2012]
- Genome-wide study identifies eight new susceptibility loci for atopic dermatitis [Last Updated On: October 7th, 2012] [Originally Added On: October 7th, 2012]
- Genome interpreter vies for place in clinical market [Last Updated On: October 10th, 2012] [Originally Added On: October 10th, 2012]
- The $1,000 Genome: A Bait and Switch? [Last Updated On: October 10th, 2012] [Originally Added On: October 10th, 2012]
- Mount Sinai School of Medicine Offers First-Ever Course with Whole Genome Sequencing [Last Updated On: October 10th, 2012] [Originally Added On: October 10th, 2012]
- First whole genome sequencing of multiple pancreatic cancer patients has been outlined [Last Updated On: October 11th, 2012] [Originally Added On: October 11th, 2012]
- Cheap genome sequences demand new rules on privacy [Last Updated On: October 11th, 2012] [Originally Added On: October 11th, 2012]
- UConn Gets Grant For Genome Research [Last Updated On: October 11th, 2012] [Originally Added On: October 11th, 2012]
- Inconsistent Genome Privacy Laws Need Toughening, Panel Says [Last Updated On: October 12th, 2012] [Originally Added On: October 12th, 2012]
- US panel calls for stronger privacy for genome data [Last Updated On: October 12th, 2012] [Originally Added On: October 12th, 2012]
- Genome Canada Board Appoints New Chair [Last Updated On: October 12th, 2012] [Originally Added On: October 12th, 2012]
- The $1,000 Genome Is Almost Here- Are We Ready? [Last Updated On: October 15th, 2012] [Originally Added On: October 15th, 2012]
- Global genome effort seeks genetic roots of disease [Last Updated On: October 31st, 2012] [Originally Added On: October 31st, 2012]
- Massive encyclopedia helps explain how the human genome works [Last Updated On: October 31st, 2012] [Originally Added On: October 31st, 2012]
- Genome evolution and carbon dioxide dynamics [Last Updated On: October 31st, 2012] [Originally Added On: October 31st, 2012]