The dancing in a rythm of human embryo development – Video

Video Link: https://www.youtube.com/watch?v=1ur9opo88zE

The dancing in a rythm of human embryo development
The timing of early embryo cleavages a non-invasive predictor of human embryo viability Embryonic genome by its transcriptional and translational activity affects the duration of the interphase and accordingly the entire cell cycle. The level of transcription and translation in the post-fertilization period is not constant and corresponds with an embryonic genome activation (EGA - Embryonic Genome Activation) Until EGA the cleaving embryonic cells have a modified cell cycles. In the first 4 interphases the two gap phases, G1 and G2, are reduced (transcriptional activity is absent/omitted), and accordingly the total length of the cell cycle is altered. Timing of early embryonic events can be used as: a prognostic tool : deciding how many embryos should be transferred and when to do ET a diagnostic tool: to assess the quality of both, the oocytes and sperm - the embryo development is a window back to the gametes a quality control: of in-vitro conditions and ART methods Conclusion The viable embryos cleave in a very similar time patterns which can be defined and applied as referencial value. The timing of early embryo cleavages can be used as an objectively measurable predictor of embryo viability and time-lapse technology should became a standard observation method in human clinical embryology. The influence of the other factors (culture media and in-vitro conditions, methods of fertilizations, hormonal stimulation etc.) must also be considered when timing is used as ...From:Daniel HlinkaViews:1 0ratingsTime:04:54More inScience Technology

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The dancing in a rythm of human embryo development - Video