Seen any clone armies in your backyard lately? Probably not. This might surprise you if you are old enough to remember the ethical panic that greeted the birth of Dolly the sheep, the first mammal cloned from an adult cell, in Scotland 21 years ago.
The cloned creature set off a crazy overreaction, with fears of clone armies, re-creating the dead, and a host of other horrors, monsters, abuses and terrors none of which has come to pass. That is why it is so important, amid all the moral hand-wringing about what could happen as human genetic engineering emerges, to keep our ethical eye on the right ball. Freaking out over impending superbabies and mutant humans with the powers of comic book characters is not what is needed.
An international team of scientists, led by researchers at the Oregon Health and Science University, has used genetic engineering on human sperm and a pre-embryo. The group is doing basic research to figure out if new forms of genetic engineering might be able to prevent or repair terrible hereditary diseases.
How close are they to making freakish superpeople using their technology? About as close as we are to traveling intergalactically using current rocket technology.
So what should we be worrying about as this rudimentary but promising technique tries to get off the launch pad?
First and foremost, oversight of what is going on. Congress, in its infinite wisdom, has banned federal funding for genetic engineering of sperm, eggs, pre-embryos or embryos. That means everything goes on in the private or philanthropic world here or overseas, without much guidance. We need clear rules with teeth to keep anyone from trying to go too fast or deciding to try to cure anything in an embryo intended to become an actual human being without rock-solid safety data.
Second, we need to determine who should own the techniques for genetic engineering. Important patent fights are underway among the technology's inventors. That means people smell lots of money. And that means it is time to talk about who gets to own what and charge what, lest we reinvent the world of the $250,000 drug in this area of medicine.
Finally, human genetic engineering needs to be monitored closely: all experiments registered, all data reported on a public database and all outcomes good and bad made available to all scientists and anyone else tracking this area of research. Secrecy is the worst enemy that human genetic engineering could possibly have.
Let your great-great-grandkids fret about whether they want to try to make a perfect baby. Today we need to worry about who will own genetic engineering technology, how we can oversee what is being done with it and how safe it needs to be before it is used to try to prevent or fix a disease.
That is plenty to worry about.
Arthur L. Caplan is head of the division of medical ethics at the New York University School of Medicine.
See the rest here:
Don't fear the rise of superbabies. Worry about who will own genetic engineering technology. - Chicago Tribune
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