TREEFROG THERAPEUTICS LAUNCHES A $100,000 RESEARCH GRANT IN REGENERATIVE MEDICINE – BioSpace

Bordeaux, France / April 19th, 2022 TreeFrog Therapeutics, a biotechnology company aimed at making safer, more efficient and more affordable cell therapies based on induced pluripotent stem cells (iPSCs), today announced the launch of The Stem Cell SpaceShot Grant, a $100,000 research funding in the field of stem cell biology and regenerative medicine.

The Stem Cell Spaceshot Grant is open to PhD-level scientists and PhD students conducting research in stem cell biology, biophysics, gene editing, cell therapy, and bioproduction engineering. With this grant, TreeFrog Therapeutics aims at supporting scientific discoveries with therapeutic impact in 4 areas:

1. Progressing stem cell culture and cell therapy products through biomimetic strategies

2. Upgrading stem cell-products and manufacturing processes using new technologies and scientific approaches

3. Improving the quality control and safety profile of stem cells and stem cell-derived transplants

4. Enhancing the engraftment, integration and long-term survival of stem-cell derived transplants

To apply, researchers only need to submit an email, a one-page research project description and a graphical abstract through an online form available on the TreeFrog Therapeutics website. Applications will be opened from May 1st to June 30th 2022. 10 nominees will be selected in August 2022. The winner will be awarded in October 2022 following interviews with an interdisciplinary jury composed of world-class experts in stem cell biology, gene editing and biophysics:

Emeritus Prof. Peter ANDREWS, University of Sheffield, UK STEM CELL GENOMIC INTEGRITY

Prof. L. MAHADEVAN, Harvard University, USA BIOPHYSICS

Marta SHAHBAZI, PhD, MRC Laboratory of Molecular Biology, Cambridge, UK DEVELOPMENTAL BIOLOGY

Justin EYQUEM, PhD, University of California San Francisco, USA GENE EDITING

Shin KAWAMATA, MD, PhD, R&D Center for Cell Therapy, FBRI, Kobe, Japan CELL THERAPY MANUFACTURING & QUALITY CONTROL

Pierre NASSOY, PhD, CNRS, France BIOIMAGING & OPTOFLUIDICS

The technology of TreeFrog Therapeutics emerged at the cross-roads of stem cell biology and biophysics after I met my co-founder, Kevin Alessandri, in an atomic bunker of the Geneva University while we were post-docs. Today, our C-StemTM technology demonstrated its capacity to mass-produce stem cells and stem cell-derived products with unprecedented scalability and quality, and TreeFrog Therapeutics raised over $82M to advance a pipeline of cell therapies to the clinic and finance the global deployment of C-StemTM. I believe its now our role to encourage the next generation of scientists to make discoveries that will shape the future of regenerative medicine. We designed the grant that we would have liked to apply to: the application process is simple, fast and anonymous - so that it is ideas, rather that resumes that are awarded , no cumbersome reporting is required, and the intellectual property of scientists is preserved. I cant wait to read the first projects!

Maxime Feyeux, PhD, co-founder and Chief Scientific Officer, TreeFrog Therapeutics

About TreeFrog Therapeutics

TreeFrog Therapeutics is a French-based biotech company aiming to unlock access to cell therapies for millions of patients. TreeFrog Therapeutics is developing a pipeline of therapeutic candidates using proprietary C-StemTM technology, allowing for the mass production of induced pluripotent stem cells and their differentiation into ready-to-transplant microtissues with unprecedented scalability and cell quality. Bringing together over 70 biophysicists, cell biologists and bioproduction engineers, TreeFrog Therapeutics raised $82M over the past 3 years to advance its pipeline of stem cell-based therapies in the field of neurodegeneration, cardio-metabolic disorders, and immuno-oncology. In 2022, the company will open technological hubs in Boston, USA, and Kobe, Japan, to drive the adoption of C- StemTM and initiate co-development partnerships with leading academic, biotech and industry players in the field of cell therapy.

Media Contact

Pierre-Emmanuel Gaultier

TreeFrog Therapeutics

+ 33 6 45 77 42 58

pierre@treefrog.fr

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TREEFROG THERAPEUTICS LAUNCHES A $100,000 RESEARCH GRANT IN REGENERATIVE MEDICINE - BioSpace