Commonly Prescribed Drug Linked to Birth Defects – Futurism

A study looking at the effects of a widely prescribed diabetes drug has linked the medication to an increased risk of birth defects.

The Danish study published in the Annals of Internal Medicine found that men who took metformin, a common drug used to treat Type 2 Diabetes, within three months before conceiving a child were 40percent more likely to have kids with birth defects.

Curiously, the study which analyzed more than a million births via national registries in Denmark between the years 1997-2016 does not get into the specifics about what kind of defects occur, only that they are genital and that these defects were found most often in male infants.

While the frequency of genital birth defects, which were the only type researchers identified as statistically significant, in children born to fathers with Type 2 Diabetes was 3.1 percent overall, the frequency increased to 4.6percent for babies whose fathers took metformin during the three months prior to conception.

The study, which focused on more than a millionbabies born to women under the age of 35 who did not have diabetes and men under the age of 40, was undertaken because, as the researchers wrote, diabetes reduces semen quality and increasingly occurs during reproductive years.

Along with looking at men who take metformin for their diabetes, researchers also focused on men who took insulin for diabetes as well and found it wasnt correlated with genital birth defects in the same way as metformin.

The researchers also found that men who took metformin prior to the three month period prior to conception werent more likely to end up with kids with birth defects.

Studies like this one are meant more to establish a correlation with the intention of future studies, and the authors acknowledged that information on underlying disease status was limited and that further research should replicate these findings and clarify the causation.

Whether the finding should affect the medication that anybody is taking at this time is an open question that experts say patients should leave up to their doctors.

In general, metformin is effective, cheap and safe to the person who is taking it. Those are important factors to consider, Maarten Wensink, an epidemiologist at the University of Southern Denmark who coauthored the research, told Live Science. Whether or not to take metformin is a decision that every patient should [discuss] with their treating physician.

But for now, these troubling findings should, if nothing else, highlight how important neonatal care is for men as well as women..

READ MORE:Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring [Annals of Internal Medicine]

More on scary birth defects:Weed-Killing Chemical Used in Deadly Agent Orange Toxin Found in 1 in 3 Americans

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Commonly Prescribed Drug Linked to Birth Defects - Futurism