Sens. Mike Lee of Utah and Thom Tillis of North Carolina announced they'd tested positive -- just days after attending a White House event where President Donald Trump nominated Barrett. Multiple attendees of that event, including Trump, have tested positive in the week since the ceremony, which featured many people not wearing masks and not observing social distancing protocols.
Senate Minority Leader Chuck Schumer on Friday renewed demands for Republicans to delay Barrett's confirmation hearings. But Senate Judiciary Chairman Lindsey Graham told CNN on Friday night he plans to move ahead with confirmation hearings on October 12 and a committee vote later in the month.
Graham said he needs the two senators to be back by October 15, when the committee will begin its debate of the nomination after the hearings are done.
The South Carolina Republican said he expects the members who have tested positive to be back in time for a committee vote on October 22. The concern is if Democrats boycott the commitee vote, the GOP may not have a quorum for that vote if both senators are absent. The committee rules require a majority of members on the panel to be present for a quorum.
But even if they don't have a quorum, Senate Majority Leader Mitch McConnell can always advance the nomination to the floor under the rules.
The greater concern for Republicans is the Senate floor vote, for which lawmakers do need to be present to vote and for which the GOP has no margin for error. If Tillis and Lee were to be gone for an extended period, it would threaten the chances of confirming Barrett, given Republicans' 53-47 majority.
Already, two other Republicans Susan Collins of Maine and Lisa Murkowski of Alaska have signaled they are unlikely to vote for Barrett because they think the high court selection should be made by whoever wins the White House on November 3.
If only Lee were out, Barrett could still get confirmed with the tie-breaking vote of Vice President Mike Pence. But if one more Republican were unavailable to vote, they wouldn't have the votes to confirm Barrett. So now that Tillis is also entering isolation, the GOP's math gets trickier since it's unknown how long the senators will be out.
Republicans have told CNN the current plan is to vote on the nomination the last week of October.
Lee tweeted on Friday that he took the test Thursday, and would "remain isolated" for 10 days. He said he has "assured" Senate Republican leaders that he will "be back to work" to join the Judiciary panel to advance Barrett's nomination to the full Senate for a confirmation vote.
"Over the last few months, I've been routinely tested for COVID-19, including testing negative last Saturday, but tonight my rapid antigen test came back positive," Tillis said.
"Thankfully, I have no symptoms and I feel well. As we all know, COVID-19 is a very contagious and deadly virus, especially because many carriers are asymptomatic. I encourage all North Carolinians to follow the recommendations of medical experts, including wearing a mask, washing hands, and practicing social distancing."
"I'm wishing @SenThomTillis a quick recovery following his positive COVID-19 test, and am thinking of him and his family," Cunningham said. "Because I was with Senator Tillis recently on the debate stage, I will also get tested."
Tillis staffers who were in contact with him this week will quarantine and get tests in the coming days, and his Charlotte campaign headquarters is closed until further notice.
Barrett tested negative for coronavirus on Friday, according to White House spokesperson Judd Deere, and CNN reported earlier Friday that she was diagnosed with coronavirus late this summer but has recovered, according to three sources familiar with the matter.
Trump disclosed that he contracted the virus hours before Lee's announcement.
Lee said he experienced symptoms "consistent with longtime allergies" on Thursday morning and took the test "out of an abundance of caution." He said he also took the test "just a few days ago" when he visited the White House for the announcement of Barrett's nomination.
"Like so many other Utahns, I will now spend part of 2020 working from home," said Lee in his statement.
CORRECTION: The graphic in this story has been updated to correctly identify Notre Dame President Rev. John Jenkins.
CNN's Jim Acosta and Pam Brown contributed to this report.
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