Category Archives: Psoriasis

Curing Psoriasis Naturally: Week 25. STALKED BY A FOX, A #39;BIG #39; FLARE UP, VEGAN lifestyle
Good week all round, until today that is. Penny has been off colour today thanks possibly a bug of some kind. She had a high temperature, which then triggered a seizure a few hours later. Thankfull...

By: Jon Maddison

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Curing Psoriasis Naturally: Week 25. STALKED BY A FOX, A 'BIG' FLARE UP, VEGAN lifestyle - Video

The Health Show: How I cured my Psoriasis in 2 Months.
I had psoriasis for about 18 years and reversed it in 2 months. Other cases that maybe worse then mine might take longer. It #39;s worth a try. She is an actress, standup comedian and most important...

By: Sal DiBella

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The Health Show: How I cured my Psoriasis in 2 Months. - Video

March 16, 2015

Credit: Thinkstock

Brett Smith for redOrbit.com Your Universe Online

Psoriasis is a medical condition typically marked by the emergence of itchy or burning patches of red, scaly skin, and those who suffer from it typically try to cope with the use of anti-inflammatory drugs and vitamin D supplements.

Now, according to a new study in The Journal of Allergy and Clinical Immunology, researchers at eight different research centers have developed a treatment that shows potential to cure the disease.

[STORY: High blood pressure and psoriasis linked]

For years, scientists have known that an inflammation-causing protein called interleukin-23 could be a key to a cure. However, past efforts have not produced very promising results.

The striking result we achieved using a human antibody that targets the signal interleukin-23 suggests we are on the threshold of doing something very different from our current model of treating psoriasis with immunosuppressive drugs throughout an adult lifetime, said study author James Krueger, head of the Laboratory of Investigative Dermatology at Rockefeller University in New York City. It raises the possibility of working toward long-term remission in other words, a cure.

In 2004, a team including Krueger indicated a major role for interleukin-23 in the disease, and study since then has backed this hypothesis. Researchers say that interleukin-23 commences a sequence of events that leads to inflammation in the skin, abnormal growth of skin cells, and dilation of blood vessels.

[STORY: Spontaneous DNA mutation causes miracle cure]

Excerpt from:
Is this the new psoriasis cure?

Health Canada just gave its stamp of approval to bring a new psoriasis drug to the shelf: Cosentyx. The injection, the first treatment of its kind, was discovered and tested by an international team of researchers led by Dalhousie Medical Schools Dr. Richard Langley.

An unmet need existed in the treatment of moderate-to-severe psoriasis, says Dr. Langley, professor and director of research in the Division of Dermatology. Using an antibody called secukinumab, we showed that for more than 80 per cent of patients, the secukinumab injection cleared up skin lesions.

In one of the largest psoriasis studies ever reported, secukinumab proved to be almost twice as effective as some other psoriasis treatments currently on the market. It achieved unprecedented levels of clearing even in severe cases. Study results were published last summer in the New England Journal of Medicine.

The effect is rapid, says Dr. Langley. We saw 50 per cent improvement within three weeks.

It was initially thought that psoriasis was caused by too much cell turnover in the skin. Instead, recent research has shown that the bodys immune system releases small proteins that spark the development of the disease.

In people with psoriasis, their IL-17A protein levels are six times higher than in normal skin, says Dr. Langley. When IL-17A levels are too high, it signals more skin cells to grow. And too many skin cells cause thickened skin and plaque to develop.

Identifying that secukinumab blocks IL-17A is one of the most if not the most impressive results that weve seen in psoriasis research, says Dr. Langley. The approval of Cosentyx, a drug targeting IL-17A, offers a new treatment option for physicians treating this condition.

Psoriasis is a chronic skin disease affecting approximately one out of 50 people. Its a systemic illness with widespread implications throughout the body. It causes painful, itchy lesions, and has been linked to a host of other health problems, such as psoriatic arthritis, inflammatory bowel disease, depression, obesity, hypertension, ischemic heart disease and stroke.

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Health Canada approves psoriasis treatment discovered through Dalled research

Treating Psoriasis and Psoriatic Arthritis

By: Healthline

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Treating Psoriasis and Psoriatic Arthritis - Video

The Psoriasis Patient Awareness Project
Calling all psoriasis patients around the world to contribute pictures to me to compile into a video. Please send your contribution to thehopefultree@gmail.c...

By: The Psoriasis Man Ray Chua

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The Psoriasis Patient Awareness Project - Video

Psoriasis Revolution Ebook
Discover how can you treat psoriasis naturally, with a proven holistic program called Psoriasis Revolution, Psoriasis Revolution is a ebook created by Dan Cr...

By: Psoriasis Revolution

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Psoriasis Revolution Ebook - Video

PSORIASIS CUASAS Y TRATAMIENTOS
http://chicassexi.blogspot.com/ https://www.facebook.com/joediaz42 https://plus.google.com/105801790719121744478/posts.

By: JOE DIAZ

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PSORIASIS CUASAS Y TRATAMIENTOS - Video

Psoriasis vs "Egg-Shaped-Foot-File"
Caution - there #39;s a little bit of blood in this one! Nothing crazy but please don #39;t watch if you get queasy at the sight of it!

By: Huy Ngo

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Psoriasis vs "Egg-Shaped-Foot-File" - Video

Only a single treatment produced what researchers describe as 'rapid, substantial, and durable clinical improvement'

IMAGE:A sample from one psoriasis patient shows thickening of the outer layer of skin, known as the epidermis (top). Eight weeks after treatment, the epidermis has thinned to a normal... view more

Credit: Laboratory of Investigative Dermatology at Rockefeller University/Journal of Allergy and Clinical Immunology

Many patients suffering from psoriasis showed significant recovery after just a single dose of an experimental treatment with a human antibody that blocks an immune signaling protein crucial to the disease, researchers report. By the end of the trial, conducted at Rockefeller University and seven other centers, nearly all of the 31 patients to receive treatment saw dramatic, if not complete, improvement in their symptoms.

"The striking result we achieved using a human antibody that targets the signal interleukin-23 suggests we are on the threshold of doing something very different from our current model of treating psoriasis with immunosuppressive drugs throughout an adult lifetime," says study author James Krueger, director of the Milstein Medical Research Program, D. Martin Carter Professor in Clinical Investigation and head of the Laboratory of Investigative Dermatology. "It raises the possibility of working toward long-term remission -- in other words, a cure." The Journal of Allergy and Clinical Immunology published the results on Thursday (March 12).

Psoriasis is a debilitating disease in which the body's immune system mistakenly turns on the skin, producing red, itchy, scaly patches. In 2004, Krueger and colleagues suggested a dominant role for interleukin-23 in the disease, and research since then has supported this hypothesis. It appears that interleukin-23, a type of immune signaling molecule known as a cytokine, kicks off a cascade of interactions that leads to inflammation in the skin and excessive growth of skin cells and dilation of blood vessels.

The discovery of interleukin-23's role has led to tests of a number of new antibody-based therapies that target it, but the compound, known as BI 655066, stands out. BI 655066 is a human antibody that targets interleukin-23 and blocks it from binding to the receptors on cells that respond to it. Only a single treatment produced what the team describes as "rapid, substantial, and durable clinical improvement in patients with moderate-to-severe psoriasis." On average, patients who received the treatment had a more than 80 percent improvement in the severity and extent of their skin lesions that continued until tracking ended six weeks after treatment. Meanwhile, genetic sequencing from skin samples revealed that the antibody's action reduced the expression of many of the cytokines and other molecules that define psoriasis.

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New antibody therapy dramatically improves psoriasis symptoms in clinical trial