Category Archives: Psoriasis

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DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/jbqhcr/global_psoriasis) has announced the addition of the "Global Psoriasis Therapeutics Market 2012-2016" report to their offering.

The analysts forecast the Global Psoriasis Therapeutics market to grow at a CAGR of 4.06 percent over the period 2012-2016. One of the key factors contributing to this market growth is the increasing uptake of biologics. The Global Psoriasis Therapeutics market has also been witnessing an increased focus on using combination therapies for treating psoriasis. However, the adverse side effects associated with psoriatic drugs could pose a challenge to the growth of this market.

Commenting on the report, an analyst from the team said: One of the main trends witnessed in the Global Psoriasis Therapeutics market is the increased focus on combination therapies. A current trend witnessed in the Global Psoriasis Therapeutics market is the use of combination therapies for treating psoriasis. Light therapy along with topical treatment products are generally used in combination for the treatment of mild to moderate level of psoriasis. For severe psoriasis oral or injected drugs are used. Due to the severe side effects of these drugs, combination of therapies is used for the effective treatment of severe psoriasis. When the disease is more severe, topic therapy products such as cream is used in combination with oral medications or light therapy. For instance, Anthralin is sometimes used in combination with UV light. Light therapy is also used sometimes in combination with medications. Moreover, in Goeckerman therapy UVB treatment and coal tar treatment is used together as it is more effective than single therapy.

According to the report, one of the main factors driving the market is the increasing uptake of biologics. In recent years the enhanced understanding of the molecular basis underlying psoriasis has led to the introduction of biological drugs, providing a new effective treatment option for this disease. Biologics aim key steps in the pathogenesis of psoriasis and can be categorized into three main categories: TNF alpha inhibitors, T cell inhibitors, and IL-12/IL-23 inhibitors.

Further, the report states that one of the main challenges is the adverse side effects. Although psoriasis drugs have numerous benefits, they can cause certain harmful side effects. Some of the common side effects caused by various psoriasis drugs are increased risk of skin cancers and lymphomas, hair loss, headache, nausea, and vomiting, suppression of immunity with possible serious infections such as pneumonia or herpes zoster.

Companies Mentioned

- Abbvie Inc.

- Amgen Inc.

- AstraZeneca plc

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Research and Markets: Global Psoriasis Therapeutics Market 2012-2016: Detailed Discussion of Trends, Drivers ...

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The psoriasis therapeutics market has been forecast to increase at a compound annual growth rate (CAGR) of 4.06% through 2016, driven by the increasing uptake of biologics, and the increased focus on using combination therapies for treating psoriasis.

Psoriasis is an immune-mediated disease that affects the skin. It is typically a lifelong condition. There is currently no cure, but various treatments can help to control the symptoms.

Psoriasis occurs when the immune system mistakes a normal skin cell for a pathogen, and sends out faulty signals that cause overproduction of new skin cells.

There are a number of different therapeutic options for psoriasis. Typically topical agents are used for mild disease, phototherapy for moderate disease, and systemic agents for severe disease.

In recent years the enhanced understanding of the molecular basis underlying psoriasis has led to the introduction of biological drugs, providing a new effective treatment option for this disease. Biologics aim key steps in the pathogenesis of psoriasis and can be categorised into three main categories: TNF alpha inhibitors, T cell inhibitors, and IL-12/IL-23 inhibitors.

Biologics are manufactured proteins that interrupt the immune process involved in psoriasis. Unlike generalised immunosuppressant therapies such as methotrexate, biologics focus on specific aspects of the immune function leading to psoriasis.

These drugs (interleukin antagonists) are relatively new, and their long-term impact on immune function is unknown, but they have proven effective in treating psoriasis and psoriatic arthritis.

When the disease is more severe, topic therapy products such as cream can be used in combination with oral medications or light therapy. For instance, Anthralin is sometimes used in combination with UV light. Light therapy is also used sometimes in combination with medications.

Furhtermore, in Goeckerman therapy UVB treatment and coal tar treatment are used together as it is more effective than single therapy.

Key players currently dominating the psoriasis therapeutics market include Amgen Inc., Pfizer Inc., Janssen Biotech Inc., and Abbvie Inc.

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Psoriasis therapeutics market driven by the increasing uptake of biologics

By Serena Gordon HealthDay Reporter

FRIDAY, Sept. 13 (HealthDay News) -- Alisha Bridges spent most of her life covering up and hiding. She didn't want the world to see the scaly patches of psoriasis that cover a significant portion of her body.

She's tried almost every treatment that's out there, with varying degrees of success, she said. Topical corticosteroids tend to work best for her, but because they can be used for only limited periods of time, she tries to restrict their use to when she has a special occasion coming up and as warmer weather approaches.

As much as 90 percent of her body is often covered with psoriasis, Bridges said.

She was only 7 years old when she was diagnosed with the autoimmune skin disease after a bout of chickenpox. Bridges said she's spent most of her life worried that people would stare, or that they'd think she had something that was contagious.

"I was hiding and being ashamed -- I was my own worst enemy," admitted Bridges, who just turned 26.

But then she started blogging about what it's like to live with psoriasis, and people took notice. She was invited to the National Psoriasis Foundation meeting in Washington D.C., where she attended a number of workshops, including one on using social media to raise awareness and connect with others.

Since then, she's been busy raising awareness through Facebook and Twitter, and she's continued to blog about living with psoriasis. She's also become a National Psoriasis Foundation community ambassador.

"Finding support is imperative in the battle with psoriasis," Bridges said. "It's so important to know that you're not alone -- that other people are also dealing with this. And, don't be afraid to speak out. When you start talking about it, people are more understanding than you expect them to be. The majority of people don't know what psoriasis is, but many are open to hearing more about it."

Support groups, she said, are great places to learn about what works and what doesn't for psoriasis, and to pick up tips -- like learning to be persistent and patient with your medication.

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Atlanta Women Offers Hope for Those With Psoriasis

By Serena Gordon HealthDay Reporter

FRIDAY, Sept. 13 (HealthDay News) -- For the legions of Americans living with the red, scaly patches of psoriasis, doctors have good news.

"We are at a point where we can help almost anyone, and we can do it fairly safely," said Dr. Mark Lebwohl, who chairs the National Psoriasis Foundation's medical board. "If you have psoriasis, there's usually a treatment out there that will make you better."

Some 7.5 million people in the United States have the autoimmune disease, yet it's unknown to millions of others.

The telltale scaly patches often occur on the outside of the elbows, knees and scalp, but they can appear anywhere on the skin and may itch, sting or burn. Some people with psoriasis also develop psoriatic arthritis, which causes stiffness, pain, throbbing, swelling and tenderness in one or more joints.

Symptoms vary from person to person, as does severity of the disease. Some people are affected mildly, while others have signs of the disease over most of their body.

But Lebwohl said there are more treatment options available today than ever before, and more are on the way. "We have medicines that are pretty safe and incredibly effective for the large majority of patients," he said.

For most people, the first line of treatment is a topical medication. Topical corticosteroids are probably the most common first treatment, he said, and they often work very well but are prone to such side effects as thinning skin and stretch marks.

Dr. Janet Lin, a dermatologist at Mercy Medical Center in Baltimore, also noted that people can develop a resistance to topical corticosteroids, which means the medication won't work any longer.

Another topical treatment is a class of medications known as vitamin D analogues, which Lin said "help normalize the growth of the skin cells, and they don't have the side effects of corticosteroids." Examples are calcipotriol, calcitriol and tacalcitol.

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Treatment Options Expand for Psoriasis Patients

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