Category Archives: Psoriasis

Popular And Effective Psoriasis Home Remedies
Watch: Popular And Effective Psoriasis Home Remedies ll health tips for women Psoriasis is a chronic skin disorder which is not contagious. This skin disorde...

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Popular And Effective Psoriasis Home Remedies - Video

By RTT News, October 08, 2014, 09:23:00 AM EDT

(RTTNews.com) - Amgen ( AMGN ) announced its Phase 3 study evaluating efficacy and safety of biosimilar candidate ABP 501 compared with Humira (adalimumab) in patients with moderate-to-severe plaque psoriasis met its primary endpoint.

The primary endpoint was the Psoriasis Area and Severity Index (PASI) percent improvement from baseline to week 16 of treatment.

At week 16, the PASI percent improvement from baseline was within the prespecified equivalence margin for ABP 501 compared to adalimumab. Safety and immunogenicity of ABP 501 were comparable to adalimumab.

ABP 501 is being developed as a biosimilar to adalimumab, an anti-TNF- monoclonal antibody, which is approved in many countries for the treatment of inflammatory diseases, including rheumatoid arthritis, plaque psoriasis (PsO), polyarticular juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease and ulcerative colitis.

"Results from Amgen's biosimilar Phase 3 plaque psoriasis study met the primary endpoint for efficacy and showed comparable safety and immunogenicity to adalimumab, which further demonstrates the Company's commitment to provide patients with access to high-quality medicines," said Sean Harper, M.D., executive vice president of Research and Development at Amgen.

Amgen said it has six biosimilar molecules in development and expects to launch the portfolio starting in 2017.

Psoriasis is a non-contagious chronic disease in which the immune system causes skin cells to grow at an accelerated rate. Instead of being shed, skin cells pile up, causing painful and itchy, red, scaly patches. Approximately 125 million people worldwide have psoriasis, and 80 percent of those patients have plaque psoriasis.

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Amgen'biosimilar Phase3 Plaque Psoriasis Study Met Primary Endpoint For Efficacy

UV-therapy allows the effective treatment of psoriasis, eczema and vitiligo in all skin areas
The compact and very inexpensive UV-therapy device medisun 250 allows the effective treatment of psoriasis, eczema and vitiligo in all skin areas. Thanks to ...

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UV-therapy allows the effective treatment of psoriasis, eczema and vitiligo in all skin areas - Video

Dr. Alan Menter - Psoriasis Types Symptoms
The more you know about living with psoriasis, the better equipped you #39;ll be to manage your psoriasis. Watch a series of videos for expert insights from derm...

By: Menter Dermatology Research Institute

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Dr. Alan Menter - Psoriasis Types & Symptoms - Video

Psoriasis station 5

By: Dr Sadek MRCP On Line Courses

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Psoriasis station 5 - Video

BlueControl can be strapped on to any part of the body

Sufferers of psoriasis, an incurable skin disease that breaks out in scaly red plaques and also causes the skin to peel, will shortly get a new ally in the management of the condition. Lighting giant Philips is about to launch BlueControl, an LED light unit that can help patients of mild and moderate cases with no side effects.

The device was developed based on findings from research showing that blue LED light treatment slows down the root cause of psoriasis, which is the rapid division of cells. It can also reduce skin inflammation. Philips designed an unobtrusive battery-powered strap-on unit that can be placed on the parts of the body that are affected by the irritating skin disease.

The system does not use regular LED lights, which are not always suitable for medical-grade applications such as BlueControl. Philips carried out research with academic and clinical partners in order to develop pulsed LED lights with higher intensities. Altogether, the system features 40 of those UV-free blue lights.

To test BlueControl, Philips teamed up with the University Hospital of Aachen in Germany. During the second of two clinical trials that spanned four months ending in June, patients showed an average reduction of 50 percent of symptoms based on a measurement system called Local Psoriasis Area Severity Index (PASI). The index measures the severity of psoriasis plaques in terms of thickness, redness and scaling. The trials also revealed that the blue LED lights produced no side effects.

Philips will present BlueControl at the European Academy of Dermatology & Venereology Congress, which takes place in Amsterdam between 8-12 October, before it goes on sale in The Netherlands, Germany and the UK.

Source: Philips

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Philips turns the light on psoriasis

DEAR DOCTOR K: My doctor thinks my arthritis and heart disease are connected to my psoriasis. Is this possible? I thought psoriasis was a skin condition.

DEAR READER: Psoriasis (pronounced so-RYE-uh-sis) is named for an ancient Greek word meaning an itchy or scaly condition. It is classified as a skin disease, but psoriasis is the result of an immune system abnormality that can cause problems throughout the body.

With psoriasis, white blood cells of the immune system become overactive. They produce excess amounts of chemicals that trigger inflammation. The inflammation leads to abnormally rapid growth of cells in the skins outer layer. This causes plaques: raised, red patches covered with silvery scales on the elbows and knees the classic sign of psoriasis. (Ive put a photo of psoriasis plaques on my website, AskDoctorK.com.)

But the effects of psoriasis are not always confined to the skin. The disease also can cause inflammation throughout the body. This probably is the reason that people with psoriasis have higher rates of various diseases that also are associated with a constant state of inflammation. These include diabetes, heart disease, high blood pressure and several types of cancer.

Nearly one-third of people with psoriasis develop psoriatic arthritis, which causes stiff, painful joints and other symptoms.

Several eye problems are more common with psoriasis, including conjunctivitis, blepharitis (inflammation of the eyelids) and damage to the cornea.

When psoriasis involves only the skin, it often can be treated just by medicines applied to the skin. Very mild cases of psoriasis may improve with moisturizers and some sunlight. But most people need other treatments:

OINTMENTS, GELS OR LOTIONS. The most common are corticosteroids, which come in varying strengths. They quickly reduce inflammation and control itching. Long-term use of strong steroids can thin and damage skin.

PHOTOTHERAPY. This treatment uses carefully controlled exposure to ultraviolet (UV) light, which helps slow the growth of skin cells. UV light combined with medicines called psoralens often are more potent than just UV light (a treatment called PUVA).

SYSTEMIC THERAPY. If your psoriasis has caused more than skin problems, this can have implications for the kind of treatment your doctor may recommend. Treatments that fight inflammation in multiple parts of the body may be required. Medicines that do this include methotrexate, retinoids and cyclosporine.

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Effects of psoriasis are not confined to the skin

Psoriatic Arthritis Psoriasis Diet #40

By: Psoriasis Channel

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Psoriatic Arthritis & Psoriasis Diet #40 - Video

Psoriasis Diet Treatment For Psoriasis
Click here: http://www.sniplink.info/RHAR56 for *much* more information.

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Psoriasis Diet Treatment For Psoriasis - Video

Psoriasis Chelation Therapy

By: Alternative Complementary Medicine

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Psoriasis Chelation Therapy - Video