Category Archives: Psoriasis

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A WOMAN who suffers from a painful skin condition says she was asked to leave a supermarket after complaints from customers about her appearance.

Psoriasis sufferer Kate Dalessio, 58, was told fellow shoppers in Sainsbury's had commented about scarring on her arms and claims the manager asked her to leave.

Angry Kate has accused the supermarket giants of treating her like a shoplifter and plans to sue.

But store bosses deny asking her to leave and say they were only trying to defuse an ugly situation as the shoppers who complained were getting more aggressive.

Managers insist they were only trying to protect Kate until the other shoppers had left and say she is welcome back any time.

The incident happened as Kate was out with her sister Alessandria, 59, at the Sainsburys store in Meadowbank, Edinburgh.

She says that she was taken to the duty managers office before being escorted out of the store in front of staff and customers.

Kate said: The duty manager told me that there had been complaints from two customers that I was being offensive.

He explained that they objected to the state of my arms.

I was wearing a sleeveless top and you could see the scarring my condition causes. The manager then took me downstairs back through the store in front of everyone to the exit.

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Woman with psoriasis claims supermarket bosses asked her to leave after customers complained about her scars

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Researchers led by the Arthritis Research UK Centre for Genetics and Genomics at The University of Manchester have identified genetic variants that are associated with psoriatic arthritis (PsA) but not with psoriasis, in the largest study of PsA ever published.

PsA is a common form of inflammatory form of arthritis causing pain and stiffness in joints and tendons that can lead to joint damage. Nearly all patients with PsA also have skin psoriasis and, in many cases, the skin disease is present before the arthritis develops. However, only one third of patients with psoriasis will go on to develop PsA.

The researchers, who are part of a European consortium, say that their work, which took three years to complete and is published in Nature Communications, is a breakthrough because genetic changes have been identified that increase the risk of PsA but not psoriasis.

Until recently opinion was divided as to whether psoriatic arthritis was a disease in its own right, or psoriasis combined with rheumatoid arthritis.

The findings could, in future, lead to the identification of people with psoriasis who are at risk of developing psoriatic arthritis.

Dr John Bowes, who led the analysis of the work, said: "Our study is beginning to reveal key insights into the genetics of PsA that explain fundamental differences between psoriasis and PsA. Our findings also highlight that CD8+ cells are likely to be the key drivers of inflammation in PsA. This will help us to focus on how the genetic changes act in those immune cells to cause disease."

The gene identified by the research team lies on chromosome 5 and is not the first PsA-specific gene to be identified. Patients who carry the HLA-B27 gene are also more likely to develop PsA.

Professor Anne Barton, a rheumatologist and senior author on the study explained: "By identifying genes that predispose people to PsA but not psoriasis, we hope in the future to be able to test patients with psoriasis to find those at high risk of developing PsA. Excitingly, it raises the possibility of introducing treatments to prevent the development of PsA in those individuals in the future."

Dr Stephen Simpson, director of research at Arthritis Research UK added:" This is a significant finding. Not only does it help establish PsA as a condition in its own right, but it could have major implications in the way that patients with this condition are treated and lead to the development of drugs specifically developed for PsA, which are greatly needed."

The research was funded by the National Institute for Health Research Manchester Musculoskeletal Biomedical Research Unit.

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Researchers find gene that confirms existence of psoriatic arthritis

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Psoriasis causes skin cells to build up rapidly on the surface.

Imagine a disease that is hiding in your genetic makeup, waiting for some external event to trigger it into existence.

When activated, this disease convinces your body that something is wrong with your own skin, causing a life-long struggle that culminates in itching, uncomfortable, embarrassing rashes that can be painful, hard to treat and impossible to cure.

Nearly 3 percent of the world's population has no need to imagine such a disease to them it is a very real ailment called psoriasis.

Psoriasis is a genetic auto-immune disease that causes skin cells to build up rapidly on the surface, creating extra-thick skin that can present itself as anything from silvery scales to red, itchy, dry patches.

Patients who have psoriasis are also predisposed to develop psoriatic arthritis, causing pain, stiffness and swelling of their joints.

No one knows exactly why psoriasis happens, but genetics, environmental factors and the immune system all figure into it. The condition is not contagious.

Certain events have been linked to triggering the condition into activity. Scientists have not discovered the direct connection but they agree that genetics are definitely involved. Of every three people with psoriasis, one will know a relative with the disease.

Amanda Jackson of Lakeland said, "My dad and his mother had it it is hereditary and not contagious, not at all." Jackson and two of her six children have it as well.

Environmental factors such as stress, injury to skin, infection, certain medications, smoking, heavy alcohol consumption, diet and allergies, can act as triggers to turn on the disease. After the initial outbreak, triggers can also cause flare-ups in the psoriasis cycle.

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Psoriasis Is an Auto-Immune Disease That Causes Itching and Rashes