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Can You Get a ‘Vaccine Passport’? And Other Questions, Answered – The New York Times

Posted: April 15, 2021 at 6:45 am

With all American adults soon to be eligible for Covid-19 vaccines and businesses and international borders reopening, a fierce debate has kicked off across the United States over whether a digital health certificate (often and somewhat misleadingly called a vaccine passport) should be required to prove immunization status.

Currently, Americans are issued a white paper card as evidence of their Covid-19 shots, but these can easily be forged, and online scammers are already selling false and stolen vaccine cards.

While the federal government has said it will not introduce digital vaccine passports by federal mandate, a growing number of businesses from cruise lines to sports venues say they will require proof of vaccinations for entry or services. Hundreds of digital health pass initiatives are scrambling to launch apps that provide a verified electronic record of immunizations and negative Covid-19 test results to streamline the process.

The drive has raised privacy and equity concerns and some states like Florida and Texas have banned businesses from requiring vaccination certificates. But developers argue that the digital infrastructure is secure and will help speed up the process of reopening society and reviving travel.

Governments, technology companies, airlines and other businesses are testing different versions of the digital health passes and are trying to come up with common standards so that there is compatibility between each system and health records can be pulled in a safe and controlled format.

The process comes with great technical challenges, especially because of the sheer number of app initiatives underway. For the certificates to be useful, countries, airlines and businesses must agree on common standards and the infrastructure they use will need to be compatible. In the United States, there is an added complexity of getting individual states to share immunization data with different certificate platforms while maintaining the privacy of residents.

Heres what we know about the current status of digital health passes and some of the roadblocks they are facing in the United States.

For the moment, only if you live in New York. Last month, it became the first state in the United States to launch a digital health certificate called the Excelsior Pass, which verifies a persons negative coronavirus test result and if they are fully vaccinated.

The app and website is free and voluntary for all New York residents, and provides a QR code that can be scanned or printed out to verify a persons health data. The pass has been used by thousands of New Yorkers to enter Yankee Stadium, Madison Square Garden and other smaller public venues.

Most businesses require people to show their state I.D. along with their Excelsior Pass to prevent potential fraud.

In Israel, where more than half the population is fully vaccinated, residents must show an electronic Green Pass to attend places such as gyms, concerts, wedding halls and to dine indoors. As part of its plans to reopen to foreign visitors, Israel has said it will require them to take a blood test upon arrival proving that they have been vaccinated. Once a vaccine certificate is introduced for travelers, the test will no longer be required.

The European Union has endorsed the idea of an electronic vaccine certificate, which could be ready by June, but each individual member country will be able to set its own rules for travel requirements. Britain has also started testing a Covid-19 certificate system that aims to help businesses reopen safely.

Some airlines including Lufthansa, Virgin Atlantic and Jet Blue have started to use the digital health app, Common Pass, to verify passenger Covid-19 test results before they board flights. The International Air Transport Associations Health Pass is being tested by more than 20 airlines and will allow passengers to upload health credentials necessary for international travel.

It depends on state regulations. The Biden administration has said there will be no federal vaccination system or mandate. Individual states hold primary public health powers in the United States and have the authority to require vaccines.

We expect a vaccine passport, or whatever you want to call it, will be driven by the private sector, Jen Psaki, the White House press secretary, said at a recent briefing. There will be no centralized, universal federal vaccinations database and no federal mandate requiring everyone to obtain a single vaccination credential.

Earlier this month, Gov. Greg Abbott of Texas issued an executive order banning government agencies, private businesses and institutions that receive state funding from requiring people to show proof that they have been vaccinated against the coronavirus.

Ron DeSantis, the Florida governor, issued a similar order, saying that requiring proof of vaccination would reduce individual freedom and harm patient privacy as well as create two classes of citizens based on vaccinations.

But those orders may not stick. The governors are on shaky legal ground, said Lawrence Gostin, the director of the ONeill Institute for National and Global Health Law at Georgetown University. Certainly, the legislature has authority to regulate businesses in the state, and it can also pre-empt counties and local governments from issuing vaccine passports. But a governor, acting on his or her own, has no inherent power to regulate businesses other than through emergency or other health powers that the legislature gives them.

In the United States, there is no centralized federal vaccine database. Instead, the states collect that information. All states except New Hampshire have their own immunization registries and some cities, like New York, have their own.

Currently states are required to share their registries with the Centers for Disease Control and Prevention, but the data is not public and could be withheld.

That means anyone developing a digital vaccine certificate in the United States would have to obtain immunization data from individual states, which could be problematic in states that oppose health pass initiatives.

One of the issues is with terminology. A passport is issued by a government and certifies personal data including a persons legal name and date of birth. Many people fear that if they are required to have one related to the coronavirus, they will be handing over personal and sensitive health data to private companies that could be stolen or used for other purposes.

There are a whole lot of valid concerns about how privacy and technology would work with these systems, especially as Silicon Valley does not have a great history delivering technologies that are privacy enhancing, said Brian Behlendorf, executive director of Linux Foundation Public Health, an open-source, technology-focused organization.

And the concept of privacy here is complicated because you are ultimately trying to prove to somebody that you received something, he said. You arent keeping a secret, so the challenge is to present and prove something without creating a chain of traceability forever that might be used.

The Linux Foundation is working with a network of technology companies called the Covid-19 Credentials Initiative to develop a set of standards for preserving privacy in the use of vaccine certificates. The main aim of the initiative is to establish a verifiable credential (much like a card in ones wallet) that contains a set of claims about an individual but is digitally native and cryptographically secure.

Some argue that such a credential would intrude on personal freedoms and private health choices.

Vaccine passports must be stopped, former Representative Ron Paul of Texas wrote in a Tweet last week. Accepting them means accepting the false idea that government owns your life, body and freedom.

Others worry that an exclusively digital system would leave some communities behind, especially those who do not have access to smartphones or the internet.

Any solutions in this area should be simple, free, open source, accessible to people both digitally and on paper, and designed from the start to protect peoples privacy, Jeff Zients, the White House coronavirus coordinator, said in a statement.

The World Health Organization said it does not back requiring vaccination passports for travel yet because of the uncertainty over whether inoculation prevents transmission of the virus, as well as equity concerns.

Follow New York Times Travel on Instagram, Twitter and Facebook. And sign up for our weekly Travel Dispatch newsletter to receive expert tips on traveling smarter and inspiration for your next vacation. Dreaming up a future getaway or just armchair traveling? Check out our 52 Places list for 2021.

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The Lessons of the Afghan War – National Review

Posted: at 6:45 am

A U.S Army soldier walks behind an Afghan policeman during a joint patrol with Afghan police and Canadian soldiers west of Kandahar, Afghanistan in 2007. (Goran Tomasevic/Reuters)Two decades of the conflict have shown us what American foreign-policy failure looks like. What success looks like remains unclear.

Joe Biden has announced that the last U.S. troops will leave Afghanistan before the highly symbolic date of September 11, 2021, the 20-year anniversary of the terror attacks that reminded all the Americans out there in TV-land that Afghanistan hadnt just disappeared after our interest in the failed Soviet engagement there faded.

This represents a small extension of the U.S. presence after the Trump administration negotiated a withdrawal originally scheduled to be complete by May 1. For many Americans and, in particular, for many conservatives this cannot come soon enough.

The George W. Bush administration is likely to be remembered as the high-water mark for a certain kind of conservatism, a certain kind of Republican Party, and a certain kind of American foreign-policy consensus. None of those has survived the 20 years since 9/11.

There was a time when conservatives embraced the adjective Wilsonian. Woodrow Wilson has come into ill repute on the right, thanks in no small part to the efforts of my friend and former National Review colleague Jonah Goldberg and his Liberal Fascism, which connected the war socialism and central-planning progressivism of Wilson et al. with similar movements, generally authoritarian, around the world. But before he was Wilson the proto-fascist, he was Wilson the muscular internationalist, an exemplary figure to the conservatives whom Colin Dueck of George Mason University describes as third-wave Wilsonians, more skeptical than their progressive peers of multilateral institutions but sharing an optimistic emphasis on worldwide democratization.

Because the American political conversation is conducted at a level of crippling oversimplification, Afghanistan was understood for a time as the new good war, while Iraq was another Vietnam, a quagmire fought on a lie. But Afghanistan was never only about hunting down al-Qaeda, and Iraq was never only or even mainly about Saddam Husseins arsenal. The more biting critique of the Bush administration is not its purported insincerity about weapons of mass destruction but its utterly sincere and culpably optimistic conviction that Afghanistan and Iraq could, with sufficient sustained effort, be remade in the liberal-democratic mold, as Japan and Germany had been after World War II. It was the domino theory in reverse: Vicious authoritarian regimes would be converted one by one as their neighbors realized the benefits of joining the U.S.-led order.

A few realists suggested that at the very least, we could succeed in making Afghanistan into something more like Pakistan; instead, the last 20 years have seen Pakistan become something more like Afghanistan, albeit a more amusing version with a partly reformed playboy-cricketeer as the face of a regime that operates as an extension of a vicious crime syndicate led by the countrys military and intelligence services with the cooperation of its religious authorities. Though we had hoped that Afghanistan would find a Benazir Bhutto figure corrupt, admittedly, but liberal and secular there was no such factotum to be found. (And Bhutto-ism, if we can call it that, mostly withered in its native soil, too.) We went into Afghanistan convinced that there was no place in the civilized world for the Taliban, and we ended up making a place at the table for the terrorist militia, conducting peace negotiations directly with its leaders while snubbing the notionally legitimate government of the Islamic republic set up under our auspices.

Theres realism, and then theres reality: Wilson didnt make the world safe for democracy, but he won his war and George W. Bush didnt win his.

Wilsonian conservatism survives in the think tanks and in syndicated columns, but it is out of power in the Republican Party. (To the extent that Democrats have their own version of muscular internationalism, it is directed at carbon dioxide.) This is partly a result of the failure of the Bush-era democracy project, and partly a result of the intense personal hatred that certain Republican figures who rose with Donald Trump have for neoconservatives and hawks such as Bill Kristol and John Bolton, the latter of whom was in the Trump administration without being of it, so to speak. But beyond the paleo distaste for Manhattan-raised Jews and people who went to Yale, the Right is being made to reengage with a very old factional dispute that long predates 9/11 or Trumps entry into politics.

In the world of conservative ideological camps, this disagreement is expressed in the confrontation of the Wilsonian tendency with the isolationist/noninterventionist/America First tendency, which runs from Charles Lindbergh and anti-war Republicans such as Senator Bob Taft to more modern figures such as Pat Buchanan, Ross Perot, Ron Paul, and Donald Trump. Populists take a nickel-and-dime view of international relations, which is why they pay so much attention to such trivial (from a purely financial point of view) issues as foreign aid. Upstarts challenging powerful incumbents or entrenched establishment figures almost invariably affect a populist demeanor that is abandoned when campaign time is over: Then-candidate Barack Obama, no paleoconservative, complained in 2008 about the money spent on nation building abroad when it could have been spent filling potholes in Sheboygan, but governed as a man who enjoyed a good drone strike. The rhetorical necessities of populism are making great things small and complex things simple. The necessities of responsible government are . . . not doing that.

To the extent that the Republican Party is converting itself into a right-wing populist party the National Farmer-Labor Party envisioned by such figures as Senator Josh Hawley it will tend to revert to the nickel-and-dime mode of Ron Paul and Donald Trump and candidate Obama. Whats in it for us? is an important question in international relations, but it needs an enlightened mind to answer it constructively. President Trump treated NATO like he was trying to divide up the bill at a restaurant after an expensive dinner and demanding to know who ordered the priciest appetizer. It is important to watch the nickels and dimes, but it also is important to spend them wisely when the time comes. Preventing 9/11 would have been very difficult, but it neednt have been very expensive.

Republicans might retreat into something like the principled pacifism of Taft, who was greatly preferred by postwar conservatives to the moderate multilateralist Dwight Eisenhower, though it is difficult to shoehorn principled and Matt Gaetz into the same sentence. Foreign policy interacts with domestic politics in complicated and unpredictable ways, but a minimalist orientation might be the best this generation of Republicans can manage a know-nothing party with a do-nothing foreign policy.

Give the Taftians this: The United States does spend too much money on the military and on related security affairs, it does maintain too many bases in too many countries around the world, it does bring unneeded troubles on itself by its occasionally rash and headlong enthusiasms, it does fail to derive as much benefit from the multilateral institutions it supports as it might, and it does pay a high price (much more than an economic price) for acting as de facto policeman of the world for being and having been for so long the principal guarantor of security in a world whose people when in danger most certainly do not cry out with one voice: Thank God! Its the Belgians! As what Professor Dueck calls the Wilsonian century fades into memory, Americans are exhausted. A period of consolidation might be of benefit.

But give the Wilsonians their due, too: When the United States retreats from the world, it does not leave a vacuum; it only creates opportunities for other actors, China prominent among them, whose leaders have ambitions as audacious as Wilsons but would remake the world along decidedly illiberal and antidemocratic lines. Unlike the Americans, the Chinese do not try to get other countries to adopt their model of government or their fundamental values they simply do their best to bully them into acting in Beijings interests. The United States will remain for such ambitious parties either an obstacle, a rival, or an outright enemy there is no imaginable outcome in which we are too quiet to take notice of.

And so while the United States may withdraw its troops from Afghanistan, that does not mean that the United States will have no interests in Afghanistan. The United States has interests everywhere, because the United States is in the world and connected to it, and it is not as easily overlooked as Finland. What we have learned from Afghanistan or what we could learn, if we are willing is what failure looks like.

What success is going to look like, we still dont know. We have spent 20 years and more than 2,300 American lives trying to figure that out, and I am not sure that we have made any real progress.

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Trump’s early endorsements reveal GOP rift | TheHill – The Hill

Posted: at 6:45 am

Former President TrumpDonald TrumpTrump mocks Murkowski, Cheney election chances Race debate grips Congress US reentry to Paris agreement adds momentum to cities' sustainability efforts MORE's recent endorsements of Sens. Ron JohnsonRonald (Ron) Harold JohnsonPelosi: Dropping 9/11-style Jan. 6 commission an 'option' amid opposition Wisconsin state Treasurer Sarah Godlewski launches Senate bid Biden picks vocal Trump critics to lead immigration agencies MORE (R-Wis.), Rand PaulRandal (Rand) Howard PaulAnti-Asian hate crimes bill overcomes first Senate hurdle Fauci on Tucker Carlson vaccine comments: 'Typical crazy conspiracy theory' Republicans need to stop Joe Biden's progressive assault on America MORE (R-Ky.) and Marco RubioMarco Antonio RubioThe Memo: Biden puts 9/11 era in rear view Intelligence leaders push for mandatory breach notification law Intelligence leaders warn of threats from China, domestic terrorism MORE (R-Fla.) are exposing a rift between Republicans who want to leave the Trump era behind and those who see his populist brand of conservatism as a winning formula.

By dropping a string of Senate endorsements almost 20 months before Election Day, Trump is inserting himself squarely in the internal debate among GOP lawmakers about where they want to go as a party and how closely they want to work with President BidenJoe BidenHouse panel approves bill to set up commission on reparations Democrats to offer bill to expand Supreme Court Former Israeli prime minister advises Iran to 'cool down' amid nuclear threats MORE.

He is also sending signals to allies that he can protect them from primary challenges next year, a potentially strong incentive for fellow Republicans not to discard his legacy.

Its a great preemptive thing to put off any potential challengers, said Jim McLaughlin, a Republican strategist, who noted that Trump has a very good relationship with Sen. Rick Scott (Fla.), head of the Senate GOPs campaign arm.

McLaughlin said Trumps growing interest in the early machinations of the 2022 election cycle will similarly send a message to Republicans that they need to fight against Bidens agenda, which aims in large part to dismantle the previous administrations policies.

Some GOP senators, like Sens. Susan CollinsSusan Margaret CollinsOVERNIGHT ENERGY: Senate confirms Mallory to lead White House environment council | US emissions dropped 1.7 percent in 2019 | Interior further delays Trump rule that would make drillers pay less to feds Anti-Asian hate crimes bill overcomes first Senate hurdle On The Money: Senate confirms Gensler to lead SEC | Senate GOP to face off over earmarks next week | Top Republican on House tax panel to retire MORE (Maine), Lisa MurkowskiLisa Ann MurkowskiTrump mocks Murkowski, Cheney election chances Biden picks Obama alum for No. 2 spot at Interior Biden outreach on infrastructure met with Republican skepticism MORE (Alaska) and Mitt RomneyWillard (Mitt) Mitt RomneyRomney, Sinema teaming up on proposal to raise minimum wage Family policy that could appeal to the right and the left Press: Corporate America defies the GOP MORE (Utah), say they want to work with Biden. They were part of a group that met with the president in early February to explore a compromise coronavirus relief package. But Biden quickly dismissed their proposal as being insufficient.

In the end, not a single congressional Republican voted for Bidens $1.9 trillion American Rescue Plan.

Some Republican lawmakers see Trumps departure from the White House as a chance to break with certain policies that were broadly unpopular in the Senate GOP conference. Among those were Trumps approach to trade and foreign policy.

Republican lawmakers havent yet decided whether they want to renounce Trumps trade and tariff practices, and Biden is keeping them in place for now.

On foreign policy, there hasnt been much pushback from the Senate Republican Conference over Bidens decision to mend fences with NATO allies. The president strongly reaffirmed the U.S. commitment to NATO in February by declaring: An attack on one is an attack on all. That is our unshakeable vow.

But for other Republicans, Trumps out-of-office support is fuel to propel their own careers and expand the GOP base among working-class voters. GOP strategists note that Johnson, Paul and Rubio all wanted Trumps endorsement.

Sen. Josh HawleyJoshua (Josh) David HawleyAnti-Asian hate crimes bill overcomes first Senate hurdle Republicans see record fundraising in months after Capitol breach Biden sparks bipartisan backlash on Afghanistan withdrawal MORE (R-Mo.) is among the handful of Republican senators who have embraced Trumps populism and see it as the future of the party.

Hawley says he will unveil a trust busting agenda for [the] 21st century this week focused on giant woke corporations" that "keep telling Bidens big lie about Georgia.

That agenda isnt sitting well with all conservatives.

I agree with the sentiments right up until he advocates for a policy that is anti-free market, said Brian Darling, a GOP strategist. The one thing Republicans have to resist more than anything is the urge to use antitrust laws to hit back at these corporations they disagree with.

Hawley also broke with much of the GOP conference last year by endorsing $2,000 stimulus checks in what became a $900 billion compromise measure passed by Congress in December. Trump also favored sending out $2,000 checks, but many Republicans balked at the idea.

At the other end of the spectrum is Murkowski, who wants the GOP to return to being the big tent party that it was under President Reagan.

If the Republican Party continues to be the party of Trump, Im not quite sure where I fit, she said in January.

She got a boost Friday when the Senate Leadership Fund, a super PAC linked to Senate Minority Leader Mitch McConnellAddison (Mitch) Mitchell McConnellThe Memo: Biden puts 9/11 era in rear view Anti-Asian hate crimes bill overcomes first Senate hurdle Greitens Senate bid creates headache for GOP MORE (R-Ky.), endorsed her for reelection in 2022.

Alaska needs the kind of experienced representation that Lisa Murkowski provides in the United States Senate, said the groups president, Steven Law, who formerly served as McConnells chief of staff.

McConnell has broken with Trump since he lost to Biden. The GOP leader stopped speaking to the president in mid-December and in February denounced his role in inciting the mob of supporterswho stormedthe Capitol on Jan. 6 while lawmakers were tallying the Electoral College vote.

Trump has been relatively quiet since being banned from Twitter in early January. But he has made his presence in Republican politics increasingly felt in recent days with a series of statements and endorsements from his post-presidential office and his Save America PAC.

The PAC has raised $85 million to bolster Trumps most loyal allies, a reminder to fellow Republicans that he intends to remain a political force.

This past week he endorsed Johnson, Paul and Rubio, three of his most loyal Senate allies, who are up for reelection next year. Johnson, who spearheaded an inquiry into Hunter Bidens work for a Ukrainian energy company a favorite Trump topic hasnt announced yet whether hell seek a third term.

Trumpurged Johnson to Run, Ron, Run! even though Democrats think they might have a better chance of winning the seat if hes the GOP nominee.

I hope he does run. It makes it easier for the Democrats to pick it up. Hes been so radical and outrageous on so many issues recently that I think it makes an easier pick up for Democrats if hes in, said Ben Nuckels, a Democratic strategist who helped Wisconsin Gov. Tony EversTony EversWisconsin Supreme Court rules against restaurant, bar capacity limits Trump's early endorsements reveal GOP rift Biden rescinds Trump-approved Medicaid work requirements in Michigan, Wisconsin MORE (D) win in 2018.

Brandon Scholz, a Republican strategist based in Wisconsin, predicted Democrats will reprise the anti-Trump tactics and rhetoric they deployed in 2020.

He said Trumps endorsement certainly is going to work for the Democrats, who are trying to create the same campaign that they ran against Donald Trump in the presidential race against Ron Johnson.

Democrats didnt run an issues-based campaign against Trump in Wisconsin, Scholz said, but instead ran one focused on his character and behavior.

They hated Donald Trump that is what the campaign was about, he said. My sense is theyre trying to recreate that campaign.

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This Florida Man may lead the GOP out of the wilderness | Column – Tampa Bay Times

Posted: at 6:45 am

You know all those Florida Man stories? Florida man arrested for throwing alligator through drive-thru window, Florida man learns the hard way he stole laxatives, not opioids, etc.?

There are several theories for why Florida men stand out so much, starting with Florida is just weird. The most interesting involves the streetlight effect, a logical fallacy inspired by the old joke about the drunk who looks for his lost car keys only under a streetlight because thats where the light is good something you could definitely see Florida Man doing.

The Sunshine State has robust sunshine laws, making it easy to get arrest information quickly. Hence, according to this theory, Florida Man is no more outlandish than, say, California Man; its just that we can see Florida man under the medias streetlight.

Interesting theory. Lets test it out.

Three Florida men former President Donald Trump, Rep. Matt Gaetz and Gov. Ron DeSantis define the Republican Party these days. Trump, a recently minted Floridian, surely deserves outsized attention as much as he craves it. He and his enablers are determined to keep the GOP in his thrall. Just over the weekend, Trump told a group of donors at Mar-a-Lago that Senate Minority Leader Mitch McConnell was a dumb son of a b---- and repeated his bogus claims about the election being stolen.

Gaetz, a leading Trump toady, is in the crosshairs of the FBI and a House ethics investigation for the alleged sex trafficking of a minor. That feels very homo floridus. Thats two for the Florida-is-weird column.

Then theres DeSantis. He has also played the role of Trump superfan and is adept at arousing media anger a job requirement on the right these days. But unlike Gaetz (and, frankly, Trump), DeSantis actually knows how to govern effectively.

Politically, the key difference between DeSantis and Gaetz is that Gaetz garners media attention by making an ass of himself, while DeSantis makes the media look asinine when it tries to make him out to be nothing more than a Trump wannabe.

The fact is, DeSantis did better with the public than Trump during the worst times of the COVID-19 pandemic and handled the pandemic better than many Democratic governors. Before the pandemic, his governing agenda earned him a 62 percent approval rating. In this case, his critics wont gain much traction by tarring him as another Florida weirdo. In fact, outlandishly unfair attacks, like CBS recent 60 Minutes report on DeSantis, are likely to gain him more support.

Some conservative pundits are already focusing on DeSantis as the face of the post-Trump right. But its early yet. Just ask former Wisconsin Gov. Scott Walker, once hailed as a fighter whod save the GOP.

The comparison with Wisconsin is instructive. For years, the Badger State punched well above its weight nationally, with Walker, former House Speaker Paul Ryan and former Republican National Committee Chair Reince Priebus dominating the GOP. Now its Floridas turn.

Trump explains some of that. The yearly Conservative Political Action Conference is essentially an arm of Trump Inc. now. Republican politicians are required to decamp for Mar-a-Lago to ask for favor or forgiveness from Trump. Trump even holds auditions for his endorsement.

But handicappers shouldnt just focus on the political Florida Man stories. The GOPs path out of the wilderness may be a long one, but it will start in Florida. Republicans cant win the Electoral College without the state. Moreover, Florida is one of Americas most demographically representative battleground states. Wisconsins hegemony brought one set of issues Ryans fixation on entitlements, for example to the fore, while Floridas ascendancy could further push up issues such as school choice on the Republican agenda.

Also, not only does Florida regularly produce Republican politicians who know how to appeal to a diverse electorate, it has a diverse electorate that is open to electing Republicans.

For years, Democrats took the slogan demography is destiny too seriously, believing that a growing electorate of nonwhite voters would guarantee victory. Florida defies those lazy assumptions.

In 2018, running against Andrew Gillum, the African American mayor of Tallahassee, DeSantis got 44 percent of the Latino vote and 30 percent of the nonwhite vote. And Trump himself improved with Latino voters in 2020.

So, score two out of three for Florida men bringing some special weirdness to the table. Still, it remains to be seen whether DeSantis can ultimately get out of Trumps shadow and into the light, or whether the Florida Man-in-Chief will even let him.

Jonah Goldberg is editor-in-chief of The Dispatch and the host of The Remnant podcast. His Twitter handle is @JonahDispatch.

2021 Tribune Content Agency, LLC.

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Recent UW grad, an Afghan Kurdish poet, wins $90,000 scholarship for immigrants with exceptional potential – University of Wisconsin-Madison

Posted: at 6:45 am

Through poetry, Hajjar Baban has found her voice and her calling.

Her chosen field, she says, allows her to be honest about my understanding of the world while changing and imagining new ways of being.

Hajjar Baban

The 2020 UWMadison graduate already has achieved considerable success. Shes now poised for more.

Baban has been named one of 30 recipients of a 2021 Paul & Daisy SorosFellowship for New Americans, a merit-based graduate school program for immigrants and children of immigrants. She was chosen from a pool of 2,445 applicants, the most in the programs history.

Baban currently is pursuing a master of fine arts degree in poetry at the University of Virginia. Each Soros Fellow receives up to $90,000 in funding to support their graduate studies.

Born in Pakistan, Baban immigrated to the U.S. with her parents when she was 2. Her mother had sought refuge in Pakistan from the Soviet invasion of Afghanistan and her father had escaped persecution in Pakistan as a Kurd in Iran.

Baban and her siblings grew up in Dearborn, Michigan. In high school, through a Google search of poetry slam events in the area, Baban began writing with InsideOut, a Detroit literary arts program. She later served as the 2017 Detroit Youth Poet Laureate.

She attended UWMadison through the First Wave Scholarship Program, the first and only full-tuition scholarship for urban arts. She majored in English and creative writing and also studied Persian, Arabic and Pashto.

Poetry, Baban says, allows her to be honest about my understanding of the world while changing and imagining new ways of being.

As a freshman, Baban was a finalist for the inaugural position of National Youth Poet Laureate. She finished second to Amanda Gorman, the poet who delivered an original composition at President Joe Bidens inauguration in January.

Baban has received both university awards and those from literary magazines, including the Charles M. Hart Jr. Writers of Promise Award, the George B. Hill Poetry Award, the Ron Wallace Poetry Thesis Prize, the Gearhart Poetry Prize, and the Matt Clark Editors Choice Prize. Her work has appeared in The Offing, Foundry Magazine, and the Asian American Writers Workshop magazine, among others. She recently completed her first full-length poetry manuscript, Singular Wreckings.

Those eligible for New American Fellowships include green card holders, naturalized citizens, Deferred Action for Childhood Arrival (DACA) recipients, individuals born abroad who graduated from both high school and college in the United States, and the U.S.-born children of two immigrants.

The award demonstrates the immense contributions that immigrants of all backgrounds make to the United States, says fellowship director Craig Harwood. Each 2021 Fellow is a reminder of what is best about this country.

Much of Babans work touches on concepts of nation and belonging. She intends to continue to look for opportunities to be in community with immigrant writers, whether as a mentor or student herself.

To me, being a New American means moving about this country with intention of my identity how it impacts, how I can heal, and what it means for those who come after me, Baban says.

Another UWMadison graduate, HaoYang (Carl) Jiang,was awarded a Soros Fellowship in 2018 to pursue a career in law.

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Recent UW grad, an Afghan Kurdish poet, wins $90,000 scholarship for immigrants with exceptional potential - University of Wisconsin-Madison

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Most differences in DNA binding compounds found at birth in children conceived by IVF not seen in early childhood – National Institutes of Health

Posted: at 6:39 am

News Release

Wednesday, April 14, 2021

NIH study results bolster previous studies finding no growth, development differences with IVF.

Compared to newborns conceived traditionally, newborns conceived through in vitro fertilization (IVF) are more likely to have certain chemical modifications to their DNA, according to a study by researchers at the National Institutes of Health. The changes involve DNA methylation the binding of compounds known as methyl groups to DNA which can alter gene activity. Only one of the modifications was seen by the time the children were 9 years old.

The study was conducted by Edwina Yeung, Ph.D., and colleagues in NIHs Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Previous studies by the research team found no differences in growth and development for this group.

Our study found only small differences in DNA methylation at birth and these were not seen in early childhood, Dr. Yeung said. When considered along with our previous studies finding no differences in childrens growth and development, our current study should be reassuring to couples who have conceived with fertility treatments and to those considering these methods.

IVF consists of collecting eggs and sperm, fertilizing the eggs in a lab, and then transferring the resulting embryo or embryos into the uterus. Another technique, intracytoplasmic sperm injection (ICSI), consists of injecting a sperm cell directly into the egg before placing the resulting embryo into the uterus.

Methylation changes were not associated with two other fertility treatments, ovulation induction (drug treatment to release the egg from the ovary) and intrauterine insemination (insertion of semen directly into the uterus).

According to a national report in 2018, almost 75,000 IVF-conceived infants (2.0% of all infants) were born in the United States. Of these, approximately 76% were conceived with ICSI. Another study found that 3 to 7% of births resulted from ovulation induction and intrauterine insemination.

When methyl groups are added to a gene, the gene is switched off and does not produce a protein. Methyl groups are added and removed from DNA throughout life, as genes are alternately switched on and off. Changes in methylation may occur in any step of IVF. These include exposure to hormones needed to bring the eggs to maturity so they can be collected or exposure to the culture medium in which the eggs are fertilized and embryos develop.

Previous studies have found associations between IVF and certain rare disorders. However, many of these studies were small and their results inconsistent. Also, many of the studies were conducted before ICSI was in widespread use.

For the current study, researchers evaluated data on DNA methylation differences in children beginning at birth and when they were 8 to 10 years old. The children were born in New York State from 2008 to 2010 and more than 70% of IVF birth were with ICSI.

Of the newborns, 157 were conceived with fertility treatments and 520 were conceived without treatments. Newborns conceived with IVF were more likely to have lower methylation levels in some parts of their DNA. The researchers did not find any methylation changes for newborns conceived by ovulation induction or intrauterine insemination.

Among the 152 children who provided DNA samples at 8 to 10 years old, 23 were conceived with IVF and 34 with ovulation induction or intrauterine insemination. For children conceived with IVF, lower methylation levels were seen for only one region, in the GNAS gene, which has been found in some previous studies but not others.

The study authors called for more research on how variations in fertility treatments could contribute to methylation differences in children, such as variations in the medium used to culture embryos.

About the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): NICHD leads research and training to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize abilities for all. For more information, visit https://www.nichd.nih.gov.

About the National Institutes of Health (NIH):NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

NIHTurning Discovery Into Health

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Most differences in DNA binding compounds found at birth in children conceived by IVF not seen in early childhood - National Institutes of Health

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Police say DNA connects suspect to a string of smash and grabs in Danville – Fox 59

Posted: at 6:39 am

DANVILLE, Ind. Danville Police credit DNA for connecting a suspect to a smash and grab crime spree.

Back in October, a husband and wife were out walking near Twin Bridges Trails. When the couple returned to their car, they found the car window busted and the womans purse was gone.

Its not like we forget about the case. We are still going to come after you, said Nate Lien, detective with Danville Police Department.

Now months later, Danville Police believe Donald Cates is the man behind the crime.

We know in our case its solid, said Detective Lien.

Lien tells FOX 59 that when Cates busted the car window, he cut himself, leaving behind his DNA. Investigators waited for the lab results to come back and got a match.

Theres no fighting that your blood is on their broken window and their stuff is stolen there. So, its one of the pieces to the puzzle that is vital to solving this case, said Detective Lien.

Police are confident the smash and grab that happened in the Danville parking lot wasnt the first for Cates. So far, hes under investigation for possibly doing the same thing at other trails in several surrounding counties. The DNR is looking into him too.

He was specifically targeting trailheads and parks, where cars are left unattendedand people are out walking and away from their cars, said Detective Lien.

Detective Lien says investigators from Hamilton County, Pendleton, and New Castle have all been working together and comparing surveillance pictures from when the suspect used stolen credit cards from vehicles.

This was the suspect in every one of the cases. Basically, weve caught him at once, said Detective Lien.

Detectives are warning criminals, no matter how much time goes by cases remain open and clues, even the ones they unknowingly left behind are helping investigators close in on them.

Theres DNA on everything. Theres DNA in saliva, hair, people dropping cigarettes. We use DNA all the time it might take a awhile but eventually youre going to get caught, said Detectives Lien.

Cates has been charged with theft, felony theft due to prior convictions, fraud, criminal mischief among other charges.

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No, the COVID-19 vaccine will not change your DNA – MLive.com

Posted: at 6:39 am

The COVID-19 vaccine wont change your DNA.

None of the three vaccines between Pfizer, Moderna or Johnson & Johnson actually enter the nuclei in a persons cell, according to the CDC, meaning none of them actually interact with DNA or a genome.

The Pfizer-BioNTech and Moderna vaccines are mRNA vaccines, which teach our cells how to make a protein that triggers an immune response, according to the CDC. The mRNA from a COVID-19 vaccine never enters the nucleus of the cell, which is where our DNA is kept. This means the mRNA cannot affect or interact with our DNA in any way.

Regarding the Johnson & Johnson shot, the material it delivers to a persons cells does not integrate into a persons DNA, the CDC states. The Johnson & Johnson vaccine was temporarily halted in Michigan following guidance from federal regulators after six people nationwide reported rare, but serious blood clots.

Infectious disease and biology experts however said none of the vaccines access or change DNA, refuting a series of conspiracy theories circling around social media.

The concern over DNA alteration was perhaps most prominently voiced in an April 8 article in The Defender, a publication run by the anti-vaccination group Childrens Health Defense. The post cited a preprinted research paper from Harvard and MIT scientists that asserts that mRNA from the virus can very rarely persist in an individuals body tissue even after infection.

Richard Young, a co-author on the paper and an MIT professor of biology, told MLive its terrible his teams research is being used in anti-vax circles, since his teams findings only address the COVID-19 virus and not any of the vaccines.

It is possible that the (COVID-19) virus might integrate on a rare instance into a human genome into tissue culture itself, Young said. But the vaccine is just a tiny piece of spike protein in an mRNA molecule. So when the vaccine mRNA goes into the cell, it only goes into the cytoplasm where it can be made into proteins by ribosomes. So it doesnt even go into the nucleus.

Spike proteins, according to the CDC, trigger our immune system cells to recognize the COVID-19 virus and begin producing antibodies to fight the infection.

Young said he and his colleagues research should be seen as more reason to avoid natural COVID-19 infection, not to avoid the vaccine. Compared to the virus, the vaccine carries less than 1% of the molecules used to replicate viral mRNA that can lead to very rare genetic alteration, Young said.

If you were weighing a concern, Id be very concerned about being infected with the virus, he said, because the virus is giving some people long COVID, whereas the vaccine doesnt seem to be hurting anyone.

Read more: Long Covid continues to stump doctors and exhaust those fighting months-long battles

While the Johnson and Johnson vaccine works differently than its counterparts, it accomplishes the same goal of creating proteins to catalyze the creation of antibodies, said Dr. Anthony Ognjan, infection disease doctor with MacLaren Macomb hospital.

Its called a viral vector vaccine, he said. Similar to AstraZeneca, what it does is it takes the virus and creates a kind of infection in people, but not really...it attaches spike proteins to the virus, the viruses are naturally taken up by the cells and then the cells process automatically an immune reaction.

The bottom-line: the COVID-19 vaccines does not get incorporated into human DNA, Ognjan said. Vaccines that treat herpes are examples of ones that can alter DNA, but the COVID-19 shots dont follow the same method.

The genetic alteration concern picks up on a fear some people have about how changed DNA leaves some individuals susceptible to cancer down the road, Ognjan said. While altered DNA does carry those risks, that fear is being conflated with the COVID-19 vaccine in a frustrating way, he said.

People who dont understand the science, anti-vaxxers and pseudoscientists are taking advantage of peoples naivety and not understanding the basic science of whats going on, he said. You see that stuff get scattered over the internet, and it drives me crazy.

Read more from MLive:

As Michigans coronavirus cases surge, experts say its hard to pinpoint an exact cause

Whitmer on CNN: Michigan could shed COVID-19 restrictions, fully reopen this summer

Michigan hospital to study COVID-19 vaccine in people with severe allergies

COVID-19 risk from touching contaminated surface is less than 1 in 10,000, new CDC study says

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No, the COVID-19 vaccine will not change your DNA - MLive.com

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Pulsed-Field Gel Electrophoresis (PFGE) for the Separation of DNA Macromolecules – AZoM

Posted: at 6:39 am

Pulsed-field gel electrophoresis (PFGE), or clamped homogeneous electrical field electrophoresis (CHEF), is a novel gel electrophoresis type for the separation of DNA macromolecules.

This is accomplished by alternating anode and cathode at specific intervals, which means that the DNA molecules have to realign themselves in the electrical field before they can continue to progress in the matrix.

Smaller molecules orient themselves much faster than larger ones, which means that they cover a larger distance in a predetermined amount of time. The separation of the DNA molecules relies on a series of various factors: voltage, runtime, buffer concentration, temperature and how fast anode and cathode are changing.

Due to the extended runtimes of PFGE protocols and the occasional high voltage, a constant and low buffer temperature is key for the success of the method. These low temperatures and long runtimes present a unique challenge for the tubes used in a PFGE setup for the transmission of the buffer solution.

Often, standard silicone tubes are employed when running a PFGE setup, as illustrated in Fig. 1. A pump (Heidolph Hei-FLOW Value 01 peristaltic pump with SP quick 1,6 pump head; B) is affixed to the running chamber (A; Fig. 2) with about 10 m of tube material fed into a cooling unit (C).

Figure 1. Setup of the PFGE apparatus. (A) shows the gel chamber in which the running buffer is located. This buffer is continuously circulated by a pump (B). About 10 meters of silicone tubing are placed in a cooling unit (C) to keep the buffer constant at low temperature. Image Credit: Heidolph North America

Figure 2. Top view on the gel chamber, the flow direction of the buffer solution is indicated by the red arrow. Image Credit: Heidolph North America

Since the apparatus is continually used with cold buffer for up to 260 hours, it is critical to choose the appropriate tubing to avoid any complications (tearing, formation of air bubbles and loss of pumping power).

Silicone tubes wear out very fast. Therefore this test will show if they can be replaced with a more robust one.

Comparison of three tubes for peristaltic pumps will be carried out with regards to their applicability in the field of PFGE. Those tested were Heidolphs Tygon Standard, Tygon 2001 and PharMed tubes with an inner diameter of 6,4 mm and a wall thickness of 1,6 mm.

The following tests have been conducted at the laboratory of Dr. Marlis Dahl, Department of Biology, Division of Biochemistry at the Friedrich-Alexander-University Erlangen-Nuremberg.

The tubing was tested in the assembly as exhibited in figures 3 and 4, in line with the protocols shown in Table 1: Protocol A was selected due to it being the most commonly used protocol in the laboratory; Protocol B was used because it has the greatest requirement regarding the runtime.

Figure 3. Experimental setup of the PFGE apparatus, showing in which direction the buffer flows (red arrow) inside of the chamber and which tubes transport the buffer to (blue arrow) and from the cooling system (yellow arrow). Image Credit: Heidolph North America

Figure 4. The connected pump with the PharMed tubing. Also shown is the flow or pump direction of the running buffer. Image Credit: Heidolph North America

Table 1. Test protocols for the examination of the tubes. Source: Heidolph North America

After the protocols, the tubing was evaluatedand it was decided if any changes were necessary.

The Tygon 2001 tubing turned out unsuitable for the intended purpose due to it being too rigid.

Already demonstrating undesirable effects in the shorter test following Protocol A: although bubble accumulation was mitigated during the day, the next morning, numerous large bubbles were found to impede pumping (that is, insufficient cooling of the gel).

Moreover, the tube appeared to be rather brittle in the area inside the pump head. The Tygon Standard tubing facilitated good buffer circulation for a slightly longer period of time, but after some use, it cracked.

This could be a result of the low temperature of the buffer, which makes the tubing less flexible and eventually leads to breakage. The PharMed tubing performed best.

Although the part of the tubing inside the pump head stretched after an extended period of use, demonstrating that the material was thinning, it still lasts much longer than a common silicone tubing.

The latter can be fitted in the same way, but wear is significantly greater, which means that the part of the tube inside the pump head must regularly move. Otherwise, tearing will occur.

These tests demonstrated that replacing conventional silicone tubing can be achieved with the longer lasting PharMed tubing for a pulsed-field gel electrophoresis assembly using the Hei-FLOW Value 01 peristaltic pump with the SP quick 1.6 pump head.

The Tygon 2001 and Tygon Standard tubing were proven to be inappropriate for the PFGE process.

Image Credit: Heidolph North America

This information has been sourced, reviewed and adapted from materials provided by Heidolph North America.

For more information on this source, please visit Heidolph North America.

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DNA Methylation Market Value Anticipated To Reach US$ 2,726.2 Million By 2027: Acumen Research and Consulting – GlobeNewswire

Posted: at 6:39 am

LOS ANGELES, April 12, 2021 (GLOBE NEWSWIRE) -- The Global DNA Methylation Market is expected to grow at a CAGR of around 13.2 % from 2020 to 2027 and reach the market value of over US$ 2,726.2 Mn by 2027.

North America holds the largest market share for the global DNA methylation market

The rapid developments in healthcare infrastructure, the presence of prominent players in this region, and massive R&D investments, North America dominates the DNA methylation market. With increased investment in product and industry R&D, demand for protein expression systems is expected to raise, as many mammalian proteins, including growth hormone, insulin, antibodies, and vaccines, are produced on a large scale. Biopharmaceutical sales have recently surpassed 30% of all new pharmaceutical sales in the country. The United States is the world's largest spender on healthcare research. All of these factors contribute to the expansion of the global DNA methylation market.

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Market Dynamics

DNA methylation in metabolic diseases, oncology, and immunology flourish the growth of global market

Oncology is one of the fields in which DNA methylation technology is widely used to develop therapeutic strategies aimed at reversing the transcriptional abnormalities inherent in the cancer epigenome. This disruption of epigenetic modifications, which include DNA methylation and histone modification, leads to changes in gene function or expression as well as cellular transformation, which leads to cancer. DNA methylation aids in the development of inhibitors of DNA methyltransferases and histone deacetylases (HDACs), which have been shown to be clinically effective in cancer treatment, demonstrating the importance of DNA methylation technology in oncology.

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Segmental Outlook

The global DNA methylation market is segmented based on product, application, technology, and end-user. By product, the market is segmented as enzymes, instruments and consumables, kits, reagents, and bioinformatics tools. Enzymes are further sub segmented into DNA-modifying enzymes, protein-modifying enzymes, and RNA-modifying enzymes. Further, instruments and consumables are sub segmented as next-generation sequencers, qPCR, mass spectrometers, sonicators, and others. Kits is further sub segmented as bisulfite conversion kits, ChIP-sequencing kits, RNA sequencing kits, whole genomic amplification kits, 5-hmC and 5-mC analysis kits, and others. Reagents are further sub segmented as antibodies, buffers, histones, magnetic beads, primers, and among others.

By application, the market is segmented as oncology, metabolic diseases, developmental biology, immunology, cardiovascular diseases, and others. Based on application, the market is segmented as oncology, metabolic diseases, immunology, and others. Based on technology, the market is segregated as DNA methylation, histone modifications, and others. By end-user, the market is segmented as academic and research institutes, pharmaceutical and biotechnology companies, and contract research organizations (CROs)

Competitive Landscape

Key companies profiled in this report involve Illumina, Inc., Merck Millipore, Abcam plc, Active Motif, Bio-Rad Laboratories, Inc., New England Biolabs, Agilent Technologies, Inc., QIAGEN, Zymo Research, PerkinElmer, Inc., Diagenode, and among others.

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Some of the key observations regarding DNA methylation industry include:

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DNA Methylation Market Value Anticipated To Reach US$ 2,726.2 Million By 2027: Acumen Research and Consulting - GlobeNewswire

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