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Category Archives: Transhuman News

Foldable, organic and easily broken down: Why DNA is the material of choice for nanorobots – Horizon

Posted: May 11, 2021 at 10:36 pm

Doctors know that we need smarter medicines to target the bad guys only. One hope is that tiny robots on the scale of a billionth of a metre can come to the rescue, delivering drugs directly to rogue cancer cells. To make these nanorobots, researchers in Europe are turning to the basic building blocks of life DNA.

Today robots come in all shapes and sizes. One of the strongest industrial robots can lift cars weighing over two tons. But materials such as silicon are not so suitable at the smallest scales.

While you can make really small patterns in solid silicon, you cant really make it into mechanical devices below 100 nanometres, says Professor Kurt Gothelf, chemist and DNA nanotechnologist at Aarhus University in Denmark. Thats where DNA comes in. The diameter of the DNA helix is only two nanometres, says Prof. Gothelf. A red blood cell is about 6,000 nanometres across.

Lego

Dr Tania Patio, a nanotechnologist at the University of Rome in Italy, says DNA is like Lego. You have these tiny building blocks and you can put them together to create any shape you want, she explained. To continue the analogy, DNA comes in four different coloured blocks and two of the colours pair up opposite one another. This makes them predictable.

Once you string a line of DNA blocks together, another line will pair up opposite. Scientists have learnt how to string DNA together in such a way that they introduce splits and bends. By clever design, you branch out DNA strands so that you now have three dimensions, said Prof Gothelf. It is very easy to predict how it folds.

Dr Patio is developing self-propelled DNA nanorobotics in her project, DNA-Bots. DNA is highly tuneable, she said. We can have software that shows us which sequences produce which shape. This is not possible with other materials at this tiny scale.

While DNA nanorobots are a long way from being used in people, with Prof. Gothelf saying that we wont see any medicines based on this in the next ten years, progress is being made in the lab. Already scientists can obtain a string of DNA from a virus, and then design using software shorter stretches of DNA to pair with and bend the string into a desired shape. This amazing technique is called DNA origami, said Prof. Gothelf. It allows scientists to create 3D bots made from DNA.

In an early breakthrough, Prof. Gothelfs research lab made a DNA box with a lid that opened. Later, another group built a barrel-shaped robot that could open when it recognised cancer proteins, and release antibody fragments. This strategy is being pursued so that one day a DNA robot might approach a tumour, bind to it and release its killer cargo.

With nanorobots we could have more specific delivery to a tumour, said Dr Patio. We dont want our drugs to be delivered to the whole body. She is in the lab of Professor Francesco Ricci, which works on DNA devices for the detection of antibodies and delivery of drugs.

Meanwhile, the network Prof. Gothelf heads up, DNA-Robotics, is training young scientists to make parts for DNA robotics that can perform certain actions. Prof. Gothelf is working on a bolt and cable that resembles a handbrake on a bike, where force in one place makes a change in another part of the DNA robot. A critical idea in the network is to plug and play, meaning that any parts built will be compatible in a future robot.

This has the potential to make a completely new generation of drugs.

Prof. Kurt Gothelf, Aarhus University, Denmark

Bloodstream

As well as carrying out specific functions, most robots can move. DNA robots are too miniscule to swim against our bloodstream, but it is still possible to engineer into them useful little engines using enzymes.

Dr Patio previously developed a DNA nanoswitch that could sense the acidity of its environment. Her DNA device also worked as a self-propelling micromotor thanks to an enzyme that reacted with common urease molecules found in our bodies and acted as a power source. The chemical reaction can produce sufficient energy to generate movement, said Dr Patio.

Movement is important to get nanorobots to where they need to be. We could inject these robots in the bladder and they harvest the chemical energy using urease and move, said Dr Patio. In future such movement will help them to treat a tumour or a disease site with more efficiency that passive nanoparticles, which cannot move. Recently, Patio and others reported that nanoparticles fitted with nanomotors spread out more evenly than immobile particles when injected into the bladder of mice.

Rather than swim through blood, nanobots might be able to pass through barriers in our body. Most problems delivering drugs are due to these biological barriers, such as mucosal layers, notes Dr Patio. The barriers are there to impede germs, but often block drugs. Dr Patios self-propelled DNA robots might change these barriers permeability or simply motor on through them.

Stability

Nanoparticles can be expelled from a patients bladder, but this option isnt as easy elsewhere in the body, where biodegradable robots that self-destruct might be necessary. DNA is an ideal material, as it is easily broken down inside of us. But this can also be a downside, as the body might quickly chew up a DNA bot before it gets the job done. Scientists are working on coating or camouflaging DNA and strengthening chemical bonds to boost stability.

One other potential downside is that naked pieces of DNA can be viewed by the immune system as signs of bacterial or viral foes. This may trigger an inflammatory reaction. As yet, no DNA nanobot has ever been injected into a person. Nonetheless, Prof. Gothelf is confident that scientists can get around these problems.

Indeed, stability and immune reaction were obstacles that the developers of mRNA vaccines - which deliver genetic instructions into the body inside a nanoparticle - had to get over. The Moderna and the Pfizer (BioNTech) vaccines (for Covid-19) have a modified oligonucleotide strand that is formulated in a nano-vesicle, so it is close to being a small nanorobot, said Prof. Gothelf. He foresees a future where DNA nanorobots deliver drugs to exactly where needed. For example, a drug could be attached to a DNA robot with a special linker that gets cut by an enzyme that is only found inside certain cells, thus ensuring that drug is set free at a precise location.

But DNA robotics is not just for nanomedicine. Prof. Gothelf is mixing organic chemistry with DNA nanobots to transmit light along a wire that is just one molecule in width. This could further miniaturise electronics. DNA bots could assist manufacturing at the smallest scales, because they can place molecules at mind bogglingly tiny but precise distances from one another.

For now though, DNA robotics for medicine is what most scientists dream about. You could make structures that are much more intelligent and much more specific than what is possible today, said Prof. Gothelf. This has the potential to make a completely new generation of drugs.

The research in this article was funded by the EU. If you liked this article, please consider sharing it on social media.

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Foldable, organic and easily broken down: Why DNA is the material of choice for nanorobots - Horizon

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Want to live 100+ years? You may need unusually good DNA repair – Big Think

Posted: at 10:36 pm

The United States of America, land of the free, is home to 5 percent of the world's population but 25 percent of its prisoners. The cost of having so many people in the penal system adds up to $80 billion per year, more than three times the budget for NASA. This massive system exploded in size relatively recently, with the prison population increasing by six-fold in the last four decades.

Ten percent of these prisoners are kept in private prisons, which are owned and operated for the sake of profit by contractors. In theory, these operations cost less than public prisons and jails, and states can save money by contracting them to incarcerate people. They have a long history in the United States and are used in many other countries as well.

However, despite the pervasiveness of private contractors in the American prison system, there is not much research into how well they live up to their promise to provide similar services at a lower cost to the state. The little research that is available often encounters difficulties in trying to compare the costs and benefits of facilities with vastly different operations and occasionally produces results suggesting there are few benefits to privatization.

A new study by Dr. Anita Mukherjee and published in the American Economic Journal: Economic Policy joins the debate with a robust consideration of the costs and benefits of private prisons. Its findings suggest that some private prisons keep people incarcerated longer and save less money than advertised.

The study focuses on prisons in Mississippi. Despite its comparatively high rate of incarceration, Mississippi's prison system is very similar to that of other states that also use private prisons. Demographically, its system is representative of the rest of the U.S. prison system, and its inmates are sentenced for similar amounts of time.

The state attempts to get the most out of its privatization efforts, as a 1994 law requires all contracts for private prisons in Mississippi to provide at least a 10 percent cost savings over public prisons while providing similar services. As a result, the state seeks to maximize its savings by sending prisoners to private institutions first if space if available.

While public and private prisons in Mississippi are quite similar, there are a few differences that allow for the possibility of cost savings by private operators not the least of which is that the guards are paid 30 percent less and have fewer benefits than their publicly employed counterparts.

The graph depicts the likelihood of release for public (dotted line) vs. private (solid line) prison inmates. At every level of time served, public prisoners were more likely to be released than private prisoners.Dr. Anita Mukherjee

The study relied on administrative records of the Mississippi prison system between 1996 and 2013. The data included information on prisoner demographics, the crimes committed, sentence lengths, time served, infractions while incarcerated, and prisoner relocation while in the system, including between public and private jails. For this study, the sample examined was limited to those serving between one and six years and those who served at least a quarter of their sentence. This created a primary sample of 26,563 bookings.

Analysis revealed that prisoners in private prisons were behind bars for four to seven percent longer than those in public prisons, which translates to roughly 85 to 90 extra days per prisoner. This is, in part, because those in private prison serve a greater portion of their sentences (73 percent) than those in public institutions (70 percent).

This in turn might be due to the much higher infraction rate in private prisons compared to public ones. While only 18 percent of prisoners in a public prison commit an infraction, such as disobeying a guard or possessing contraband, the number jumps to 46 percent in a private prison. Infractions can reduce the probability of early release or cause time to be added to a sentence.

It's unclear why there are so many more infractions in private prisons. Dr. Mukherjee suggests it could be the result of "harsher prison conditions in private prisons," better monitoring techniques, incentives to report more of them to the state before contract renewals, or even a lackadaisical attitude on the part of public prison employees.

The extra time served eats 48 percent of the cost savings of keeping prisoners in a private facility. For example, it costs about $135,000 to house a prisoner in a private prison for three years and $150,000 in the public system. But longer stays in private prisons reduce the savings from $15,000 to only $7,800.

As Dr. Mukherjee remarks, this cost is also just the finance. Some things are a little harder to measure:

"There are, of course, other costs that are difficult to quantify e.g., the cost of injustice to society (if private prison inmates systematically serve more time), the inmate's individual value of freedom, and impacts of the additional incarceration on future employment. Abrams and Rohlfs (2011) estimates a prisoner's value of freedom for 90 days at about $1,100 using experimental variation in bail setting. Mueller-Smith (2017) estimates that 90 days of marginal incarceration costs about $15,000 in reduced wages and increased reliance on welfare. If these social costs were to exceed $7,800 in the example stated, private prisons would no longer offer a bargain in terms of welfare-adjusted cost savings."

It is possible that the extra time in jail provides benefits that counter these costs, such as a reduced recidivism rate, but this proved difficult to determine. Though it was not statistically significant, there was some evidence that the added time actually increased the rate of recidivism. If that's true, then private prisons could be counterproductive.

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Want to live 100+ years? You may need unusually good DNA repair - Big Think

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DNA ‘Lite-Brite’ is a promising way to archive data for decades or longer – The Conversation US

Posted: at 10:36 pm

The Research Brief is a short take about interesting academic work.

We and our colleagues have developed a way to store data using pegs and pegboards made out of DNA and retrieving the data with a microscope a molecular version of the Lite-Brite toy. Our prototype stores information in patterns using DNA strands spaced about 10 nanometers apart. Ten nanometers is more than a thousand times smaller than the diameter of a human hair and about 100 times smaller than the diameter of a bacterium.

We tested our digital nucleic acid memory (dNAM) by storing the statement Data is in our DNA!n. We described the research in a paper published in the journal Nature Communications on April 22, 2021.

Previous methods for retrieving data in DNA require the DNA to be sequenced. Sequencing is the process of reading the genetic code of strands of DNA. Though it is a powerful tool in medicine and biology, it wasnt designed with DNA memory in mind.

Our approach uses a microscope to read the data optically. Because the DNA pegs are positioned closer than half the wavelength of visible light, we used super-resolution microscopy, which circumvents the diffraction limit of light. This provides a way to read the encoded data without sequencing the DNA.

The patterns of DNA strands the pegs light up when fluorescently labeled DNA bind to them. Because the fluorescent strands are short, they rapidly bind and unbind. This causes them to blink, making it easier to separate one peg from another and read the stored information. We use the fluorescent patterns of each pegboard as a code to store chunks of data.

The microscope can image hundreds of thousands of the DNA pegs in a single recording, and our error-correction algorithms ensure we recover all of the data. After accounting for the bits used by the algorithms, our prototype was able to read data at a density of 330 gigabits per square centimeter.

Youre not likely to have a DNA storage device in your phone or computer, at least anytime soon. DNA data storage is promising for archival storage storing large amounts of information for long periods of time. DNA can store a lot of information in a small space. It would be possible to store every tweet, email, photo, song, movie and book ever created in a volume equivalent to a jewelry box. And data stored in DNA could last for centuries, given that the biomolecule has a half-life of over 500 years.

Researchers have been developing methods of storing data in DNA for several decades. Those methods involve the design and synthesis of unique strings of information made from the DNA nucleotides adenine (A), thymine (T), cytosine (C) and guanine (G). This information is recovered by reading the strings using sequencing technology.

From here, our goal is to increase the amount of data that we can store in dNAM, decrease the amount of time it takes to write and read the data, and use the technique to encrypt data.

[Get our best science, health and technology stories. Sign up for The Conversations science newsletter.]

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DNA 'Lite-Brite' is a promising way to archive data for decades or longer - The Conversation US

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Lin ’22 Wins Poster Award for Work on DNA, Chromosomes, and Gene Regulation – Wesleyan Connection

Posted: at 10:36 pm

Shawn H. Lin 22

Shawn H. Lin 22 is the recipient of a 2021 poster award from the American Society for Biochemistry and Molecular Biologys 25th Annual Undergraduate Poster Competition. Lins poster took the prize in Category 3: DNA, Chromosomes and Gene Regulation.

This is the second poster award Lin has won this year. In March, he was honored with the Biophysical Societys Undergraduate Poster Award for his work titled Elucidation of Interactions Between Integration Host Factor and a DNA Four-Way Junction.

Lin is a Freeman Asian Scholar from Taiwan and is majoring in Molecular Biology and Biochemistry (MB&B). Lin also works in the labs of his advisors, Ishita Mukerji, Fisk Professor of Natural Science and professor of molecular biology and biochemistry,and Candice Etson, assistant professor of physics.

Lin, along with four other students, has recently been inducted into the American Society for Biochemistry and Molecular Biology Honor Society.

Tags:biochemistry Class of 2022 student achievements

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Structure of DNA actively involved in genome regulation, study shows – Drug Target Review

Posted: at 10:36 pm

Researchers have shown that topoisomerase TOP2A eliminates negative supercoiling, causing an increase in the number of turns of DNA strands and impacting gene expression.

Researchers have shown that the supercoiling characteristic of DNAs structure controls gene expression, rather than being a collateral damage to be solved as had been thought to date. The study was conducted at the Spanish National Cancer Research Centre (CNIO), in collaboration with other researchers.

According to the researchers, the two metres of (stretched) DNA contained in human cells are continuously twisting and untwisting to give access to genetic information. When a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling that needs to be resolved later.

These results are a first step towards understanding supercoiling as an important regulator of the genome and not only as a problem associated with the metabolism of DNA, said lead researcher Felipe Corts.

The team say that this regulation occurs mainly on specific genes, namely those that are induced very quickly hundreds of times in only a few minutes such as the genes that respond to stress, cell proliferation signals, hormones or those involved in neuronal stimulation.

Topoisomerases are proteins that act on DNA, relaxing this topological stress by eliminating both an excess (positive supercoiling) and a defect (negative supercoiling) in the number of turns of the double helix compared to its normal relaxed structure.

The researchers demonstrated in this study that topoisomerase TOP2A eliminates negative supercoiling at gene promoters, thereby causing an increase in the number of turns of DNA strands in these regions. This hinders the opening of the double helix, preventing the RNA polymerase from advancing and leaving it ready to quickly trigger gene activation when required by the cell.

Topoisomerases are considered gene activation facilitators, although here we demonstrate that topoisomerase TOP2A acts in the promoter regions of genes such as c-FOS [cell proliferation regulator] to keep them repressed, but creating a particular topological context that allows them to be activated quickly in order to provide an immediate response to stimuli, said Corts.

The researchers also suggest the possibility of other functions of DNA supercoiling, such as facilitating a three-dimensional (3D) conformation of the genome favouring interactions between regulatory elements for gene expression.

This new form of genomic regulation through supercoiling highlights its potential involvement in processes that are fundamental to cell function and that require profound changes in gene expression programmes, such as cell differentiation or reprogramming, as well as in tumour transformation and progression.

The paper also opens up the possibility of using topoisomerase inhibitors to modulate these processes and cellular responses and perhaps even as possible antitumour therapies, concluded Corts.

The results are published in Cell Reports.

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Structure of DNA actively involved in genome regulation, study shows - Drug Target Review

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Battle Ground man discovers relatives through DNA testing – The Reflector

Posted: at 10:36 pm

Battle Ground resident Lee Cutbirth added some love and long lost family members to his life this year.

Born in Torrance, Calif. in October of 1957, Cutbirth spent the first few years of his life thinking he had no biological brothers and sisters. Until he was adopted by Norm Cutbirth at the age of nine, Cutbirth and his cousin, Michael Heiller lived with a few different family members in southern California.

Mike and I lived with my (biological) mother and (biological) father for just a short time, Cutbirth said. Mike was still a baby when we were given to my grandparents.

Now 63, Cutbirth lives in Battle Ground with his wife, Allison. In 2007, Cutbirth was diagnosed with retinitis pigmentosa, a rare hereditary disease that causes the eyes and vision to degenerate, resulting in vision loss and impairment. Cutbirth has been legally blind since 2016. He retired after nearly 40 years in the food industry.

Due to his condition, Cutbirth learned he was eligible for a study at the Oregon Health and Science University, barring one unique exception.

Part of the requirement for the study is that you have to have DNA available for both sides of the family, Cutbirth said. I didnt have that.

At the urging of his wife, Cutbirth looked into DNA testing companies. After reading the privacy statements of several, he decided to give 23andMe a shot.

I also wanted to see if I could find any relatives on my fathers side, he said. Good news is, I found my relatives. Bad news is, the family story of my biological father is rather awful.

After sending in his DNA sample, Cutbirth was contacted through the 23andMe website by Joan Singleton, a first cousin he had never met.

Finding out about new family members wasnt a completely new experience for Cutbirth. When he was in his 30s, he and Heiller learned they werent cousins. Rather, the duo shared a biological mother and likely the same biological father, John Edward (Jack) Lawless.

My biological father wasnt a peach, Cutbirth said. He was a womanizer.

Singleton is the daughter of Jack Lawless brother, Walter, and reached out to Cutbirth in an attempt to connect with her newly found cousin. In an email from Singleton, Cutbirth learned he had a few family members he had never known about, including his half-sister, Geraldine Gerry Piper.

Everything was a bit overwhelming at first, Cutbirth said about finding his long lost family members. Its really nice to find family and its a hell of a story. Out of everything I learned, the positive is Gerry, who had a much rougher life than I had.

According to Cutbirth, Piper was born at the same hospital as him in Torrance, Calif., just a few months later in January of 1958.

Adopted at birth, his half-sister Piper has been on a quest her whole life to find her biological family. According to Cutbirth, once California changed some laws regarding adoption records in the early 2000s, Piper was able to obtain a copy of her birth certificate.

They didnt even give her a name, Cutbirth said about Pipers biological mother and father.

In March, Singleton connected Cutbirth and Piper over email and the duo immediately hit it off.

Gerry and I have really only known each other for two months and the connection was amazing, Cutbirth said. There really is something to be said about biology. The connection was instantaneous.

Cutbirth said he and his new-found half-sister spend a few hours each week talking to each other over the phone. Despite only knowing each other for a few months, Cutbirth said the two have a lot in common. They have very similar tastes in food, enjoy the outdoors and have a knack for adrenaline.

She has it on her bucket list to do tandem skydiving. When she comes over here were going over to Depoe Bay in a Zodiac, he said.

Piper said learning about her long lost brother was surprising and exciting. It felt like she had fulfilled a life-long dream, she said.

I basically spent 59 years of my life not knowing any biological family at all except for my only daughter, she said. I immediately told (Cutbirth) to reach out anytime. He called me later that day and it was a dream come true.

Piper expressed resentment over adoption laws mandating sealed records in the country and believes that adoptees should be entitled to their birthright when they become of legal age. While she felt some of her childhood and experiences with Cutbirth were denied due to sealed record laws, Piper said shes grateful for DNA technology, which will allow her to meet her half-brother.

I am beyond grateful that he did 23andMe and we were able to connect that way and find each other, she said. Its sad to think of the adventures we couldve been on but that doesnt mean we still cant have some.

Piper echoed Cutbirths expression about hitting it off immediately. She has plans to fly into Portland International Airport on Wednesday, May 12 for a week of fun-filled events with Lee and Allison Cutbirth. They plan to go whale watching at Depoe Bay, ziplining at Skamania Lodge and will visit Multnomah Falls. Cutbirth expressed joy about finally meeting Piper in-person and said he cherishes the relationship. He wants to travel to Florida someday to see Pipers neck of the woods.

It is emotionally indescribable, Piper said about connecting with Cutbirth. Its exciting that we get to share these experiences together as siblings for the very first time. My excitement is beyond words.

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$609.8 Million Worldwide Recombinant DNA Technology Industry to 2027 – Impact of COVID-19 on the Market – ResearchAndMarkets.com – Business Wire

Posted: at 10:36 pm

DUBLIN--(BUSINESS WIRE)--The "Recombinant DNA Technology - Global Market Trajectory & Analytics" report has been added to ResearchAndMarkets.com's offering.

Amid the COVID-19 crisis, the global market for Recombinant DNA Technology estimated at US$609.8 Million in the year 2020, is projected to reach a revised size of US$841.3 Million by 2027, growing at a CAGR of 4.7% over the period 2020-2027.

Medical, one of the segments analyzed in the report, is projected to record 5.2% CAGR and reach US$631.4 Million by the end of the analysis period. After an early analysis of the business implications of the pandemic and its induced economic crisis, growth in the Non-Medical segment is readjusted to a revised 3.4% CAGR for the next 7-year period.

The U.S. Market is Estimated at $179.7 Million, While China is Forecast to Grow at 4.4% CAGR

The Recombinant DNA Technology market in the U.S. is estimated at US$179.7 Million in the year 2020. China, the world`s second largest economy, is forecast to reach a projected market size of US$148.5 Million by the year 2027 trailing a CAGR of 4.4% over the analysis period 2020 to 2027. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at 4.5% and 3.7% respectively over the 2020-2027 period. Within Europe, Germany is forecast to grow at approximately 3.9% CAGR.

Select Competitors (Total 32 Featured):

Key Topics Covered:

I. METHODOLOGY

II. EXECUTIVE SUMMARY

1. MARKET OVERVIEW

2. FOCUS ON SELECT PLAYERS

3. MARKET TRENDS & DRIVERS

4. GLOBAL MARKET PERSPECTIVE

III. MARKET ANALYSIS

IV. COMPETITION

For more information about this report visit https://www.researchandmarkets.com/r/d4621s

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$609.8 Million Worldwide Recombinant DNA Technology Industry to 2027 - Impact of COVID-19 on the Market - ResearchAndMarkets.com - Business Wire

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Even More Jurassic World, Camp Cretaceous, and Mr. DNA Merchandise Roams Into Universal’s Islands of Adventure – wdwnt.com

Posted: at 10:36 pm

Another day, another set of new dino gear in Jurassic Park at Universals Islands of Adventure. Were starting to think this new line of merchandise is as long as Mr. DNAs namesake. Lets take a look at todays finds!

This tan tee features the mighty T-Rex and a warning to Keep Your Distance.

The shirt is also branded with Universal Studios.

If you like coordinating your accessories, theres a gray backpack to match the t-shirt above. It has the same T-Rex image and Keep Your Distance text.

There is one zippered pocket on the front of the bag.

The Let Em Live, Let Em Roam logo stamp of the fictional Rural Dinosaur Conservationists of the United States of America returns, this time on a gray sweatshirt.

Various dinosaur footprints make their way up the sleeves.

This bright orange youth t-shirt bears a reminder of Camp Cretaceous #1 Rule: Dont Get Eaten. The Camp Cretaceous logo and a Velociraptor head are also featured.

Another piece of Mr. DNA merchandise has arrived! This sleek black mug showcases Mr. DNA and his new retro-style logo on one side and the Jurassic World logo on the other.

You can match your kids socks to their shirt with these Camp Cretaceous socks featuring the same friendly reminder to avoid becoming dino-chow.

The other side of the socks has a whole flock of velociraptors and the Camp Cretaceous logo.

Mr. DNA, we meet again. These stylish socks star the strand of DNA plus a guide on How to make a dinosaur.

Everything (except the socks) was found at Jurassic Outfitters. The socks were found in the Dino Store, adjacent to Burger Digs.

While we were shopping, we noticed a lot of the VelociCoaster merchandise had been removed from the main stores. A new Jurassic World Tribute Store is coming soon to Universal Studios Florida, so likely the merchandise has been moved there.

Stay tuned to UPNT for more Jurassic Park and VelociCoaster news.

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Even More Jurassic World, Camp Cretaceous, and Mr. DNA Merchandise Roams Into Universal's Islands of Adventure - wdwnt.com

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USDA May Allow Genetically Modified Trees to Be Released Into the Wild – NewsClick

Posted: May 9, 2021 at 11:48 am

On August 18, 2020, the U.S. Department of Agriculture (USDA) published apetitionby researchers at the State University of New York College of Environmental Science and Forestry (ESF) seeking federal approval to release their genetically engineered (GE)Darling 58 (D58) American chestnut treeinto U.S. forests. Researchers claim the transgenic D58 tree will resist thefungal blightthat, coupled with rampant overlogging, decimated the American chestnut population in the early 20th century. In fact, the GE American chestnut is aTrojan horsemeant to open the doors to commercial GE trees designed for industrial plantations.

The D58 would be the first GE forest tree approved in the U.S. and the first GMO intended to spread in the wild. (GE canola plants werediscoveredin the wild in 2010 but that was unplanned.) This is a project to rapidly domesticate a wild species through genetic engineering and accelerated breeding, and then to put it back into ecosystems to form self-perpetuating populationsan intentional evolutionary intervention that has never been attempted before with any species,explainscientists at the Center for Food Safety (CFS) and International Center for Technology Assessment (ICTA), which are nonprofits based in Washington, D.C.

The Southern U.S. is global ground zero for the forest products industry and we see genetically engineered chestnut trees as this industrys sneaky way of opening the floodgates for frankentrees that will harm forests, biodiversity and local communities across the region,explainsScot Quaranda of Dogwood Alliance, a nonprofit based in North Carolina that works to protect Southern U.S. forests. Our natural forests that support wildlife and the economic sovereignty of rural communities will rapidly be replaced with tree plantations for wood pellets, paper and more, leaving environmental and climate injustice in their wake.

The GE American chestnut faces an uphill battle due to decades of opposition to GE trees by Indigenous peoples, scientists, students, activists, foresters and others, including aGE tree ban by the Forest Stewardship Counciland a United Nationsdecisionthat warns countries of the dangers of GE trees and urges use of theprecautionary principlewhile addressing the issue.

By October 19, 2020, the close of the public comment period on the petition,109 organizations, representing millions of members, plus an additional 123,426 individualshad registered their opposition to the D58. The next step is the creation of a draft Environmental Impact Statement (EIS) by the USDA recommending action on the petition. The American Chestnut Foundation (TACF) estimates this could take up to a year to complete. Following this, another public comment period will be undertaken to review the draft EIS, after which the agency will develop a final EIS with a decision on the petition.

D58 Safety Studies Invalid, Warn Scientists

While American chestnut trees are known to livehundredsof years, D58 trees have only been growingsince2017, calling into question the ESFpetitionassertion that Darling 58 has been studied in detail and no plant pest or environmental risks have been observed.

In areport on the GE American chestnutshe co-wrote, Dr. Rachel Smolker from Biofuelwatch explains, Given the long lifespan of trees and varying environmental conditions they face, we cannot extrapolate from tests done on very young trees under controlled lab and field conditions. How GE trees might behave in the diverse and changing context of natural forests over long periods of time is unknown and likely to remain unknown even after they are released.

Scientists at CFS and ICTAwarn ofproblems with the D58 safety studies,writing, Given the young age of Darling 58 trees and corresponding dearth of tissue samples, conclusions from most of the animal experiments described in the Petition are too preliminary to depend upon.

In studying ESFs assessment of the impacts of inserting the blight-resistant oxalate oxidase (OxO) transgene into the chestnut genome, both CFS and ICTA furtherpoint outthat some D58 studies did not, in fact, use material from transgenic D58 trees, rendering them invalid. Petitioners did experiments to study how bumblebees might be affected by Darling 58, but did not have enough Darling 58 pollen for the experiments so used non-transgenic pollen instead, to which they added purified OxO from barley seeds. Other important initial studies on animals reported in the Petition are of limited use because they involved feeding leaves from the Darling 4 instead of Darling 58 even though Darling 4 has much lower levels of OxO in leaves again invalidating the conclusions for risk assessments. The Darling 4 was an earlier version of the American chestnut genetically engineered with the OxO transgene.

While researchers have argued that a strict regulatory process will ensure the safety of the D58 GE tree, a 2019 report by the National Academies of Sciences, Engineering, and Medicine titled, Forest Health and Biotechnology: Possibilities and Considerations, raises flags: Forest health is not accounted for in the regulations for the use of biotechnology or for other approaches to mitigating forest tree insect pests or pathogens. There are no specific regulations or policies that those agencies apply to biotech trees.

Profit Motive Trumping Morality?

Proponents argue that there can be no downside to releasing a tree engineered to resist an introduced blight. But like fire suppression, which has led to devastating wildfires due to an unnatural buildup of flammable materials in the forest, the future impacts of even a well-meaning action can become catastrophic, especially in combination with the unpredictable effects of climate change and extreme weather. Yet, researchers are engineering trees with the conviction that because they can, they should.

In her bookCan Science Make Sense of Life?, Dr. Sheila Jasanoff, Pforzheimer Professor of Science and Technology Studies at the Harvard Kennedy School, explains the implications of this arrogance. For life scientists and their enthusiastic promoters, the arc of the technologically possible, often coincident with the promise of financial gain, increasingly defines the boundaries of the morally permissible.

Researcher William Powell, whose GE American chestnut research hasreceivedboth financial and technical support from companies with a vested interest in the approval of the GE American chestnutincluding Monsanto, ArborGen andDuke Energydefendshis approach. In an article in the Conversation, Powell says, One of the key advantages of genetic engineering is that its far less disruptive to the original chestnut genomeand thus to its ecologically important characteristics. The trees remain more true to form with less chance of unforeseen and unwanted side effects. Once these genes are inserted, they become a normal part of the trees genome and are inherited just like any other gene.

However, in a briefing paper published by the Federation of German Scientists, Dr. Ricarda Steinbrecher, a molecular geneticist, and Antje Lorch, a biologist, counter that the genetic engineering process is inherently risky. Thepaperstates, It is well documented that the processes of plant transformation give rise to many mutations throughout the plant genome as well as at the insertion site of the transgene. Any robust risk assessment study needs to take several generations into account, for example to assess the stability and heritability of the transgene, unintended side effects and changes due to transformation impact.

Why the American Chestnut?

The D58 American chestnut is the culmination of decades of effort to open the doors to GE trees in the U.S. by biotechnology and timber companies. In 1999, Monsanto joined with timber companies from the U.S. and New Zealand to form a forestry biotechnology joint venture, which later became ArborGen, one of the worlds leaders in GE tree research and development. GE tree research was originally focused on trees and traits valued by the forest products industry; trees like poplar, pine and eucalyptus, and traits like insect resistance, herbicide tolerance, faster growth or altered wood composition.

Other early associationsincluding theTree Genetic Engineering Research Cooperativeat Oregon State University, launched in 1994brought together university researchers with timber and biotechnology giants as well as the U.S. Forest Service to develop genetically engineered trees for industrial timber plantations.

These efforts were met with widespread opposition and sabotage, leading the industry to conclude that they needed a charismatic test tree to try to win over the public opinion relating to GE trees.

A 2007published paperexplains, There is opposition to commercial application of trees, engineered specifically for fast growth and increased yields, by those whose stance is that the value accrues only to big companies. It will remain for traits that have broad societal benefits, such as conservation for acceptance to be gained.

The D58 is seen as a positive example for the beleaguered biotechnology industry of the benefits of biotechnology for conservation. Duke Energy also sees the American chestnut for its value as a greenwashing tool. Duke Energy invested millions into the GE American chestnut through theForest Health Initiative. Its hope was to use the American chestnut to help green its devastated mountaintop removal mining lands.

Naturalist and author Bernd Heinrich has one such grove growing on his land in Maine. In aNew York Times op-edin 2013, he wrote, I have been enjoying American chestnuts for several years now, harvested from some trees that are now part of my forest of 600 acres in western Maine. I planted four seedlings in the spring of 1982. Beyond all my expectations, the trees thrived, and some are now 35 feet tall. In my small corner of western Maine, the American chestnut is now promising to again become a significant component of the ecosystem.

Once dominant in Eastern U.S. forests, the American chestnut was highly valued for its beautiful and rot-resistant wood, and abundant nuts. While few actually remember the tree, which largelydisappearedfrom the landscape by the 1920s, a public relations effort was launched in the early 2010s with articles appearing in numerousmajor publicationsheralding the return of this mighty giant through the wonders of genetic engineering.Millions of American chestnut stumps, meanwhile, continue to send up shoots that occasionally grow into trees large enough to produce nuts, and in some locations, wild American chestnuts are spreading on their own, showing at least some evolving blight tolerance.

Another decades-long program by theAmerican Chestnut Cooperators Foundationis successfully breeding pure wild American chestnuts that are naturally blight-resistant.

In spite of examples like this, GE chestnut proponents have declared the American chestnut functionally extinct, and insist that itssurvivalhinges on the release of unproven and risky genetic engineered American chestnut trees into forests. But Lois Breault-Melican, a former board member of the American Chestnut Foundation whopublicly resigned from the TACFover the organizations support for the GE American chestnut, points out that this argument ignores the risks posed to organic and other chestnut growers: These growers are concerned about the potential GMO contamination of their orchards caused by the unregulated and unmonitored planting of genetically engineered American chestnut trees. If theUSDA approves these GE American chestnuts, the integrity of chestnut orchards would be forever compromised.

Indigenous Sovereignty Concerns

Indigenous peoples in the regions of proposed D58 releases have expressed concern that unregulated distribution of a GE tree would violate their sovereign right to keep their territories free from GMOs. They insist that Indigenous peoples be consulted in theprocessof reviewing the D58 American chestnut.

Today, there remain large areas of traditional and treaty lands on which much is forested and managed as sovereign territory of many different Native American Peoples,explainsBJ McManama of the Indigenous Environmental Network. These forests are not only a source of economic self-determination but hold great cultural significance to include sacred sites where trees are an element of sustenance, knowledge and familial identity. Every living being within the forests [is] related in some form and nothing within these lands lives in isolation; therefore, changing or altering the original instructions of any one or any part of these elements threatens the natural order established over millennia.

The Eastern Band of Cherokee, members of the Lumbee Tribe of central North Carolina and Seminole Peoples from unceded Florida territory joined the Campaign to STOP GE Trees foran October 2014 gatheringin the mountains of North Carolina to protest GE trees as a form of colonization. Their concerns were focused on the GE American chestnut trees.

Lisa Montelongo, a member of the Eastern Band of the Cherokee,explained, Im very concerned that GE trees would impact our future generations and their traditional uses of trees. Our basket makers, people that use wood for the natural colors of our clay workthere would be no natural life, no cycle of life in GE tree plantations.

Following the camp, the Bands Tribal Council passed a unanimous resolution prohibiting GE trees from their lands: Eastern Band of the Cherokee Indians (EBCI) Tribal Council Resolution No. 31 (2015): We commit to rejecting biomass, genetically engineering the natural world, carbon trading, carbon offsets and carbon sequestration schemes as they are false solutions to the climate change. Concerns were focused on the inability of the tribe to keep the GE American chestnut tree off of their lands if it were released into surrounding forests, which they describe as a violation of the Free, Prior and Informed Consent mandate under theUNs Declaration on the Rights of Indigenous Peoples.

Global Impact of the Genetically Engineered D58 American Chestnut Tree

In the end, the potential deregulation of the D58 is not about restoring a mighty giant to Eastern U.S. forests. Its approval is about paving the way for the deregulation of all GE trees, toward the creation of an oxymoronic future bioeconomy where biodiverse forests are replaced with specially engineered trees for the manufacture of fuels, chemicals, textiles, plastics and other goods in a green version of business as usual. Implicit in this scheme is a massive increase in the consumption of wood. This in turn will drive accelerated conversion of carbon-rich native forests, critical for climate regulation, and other ecosystems for conversion to fast-growing plantations that include GE trees with traits to expedite their use as feedstocks. Existing non-native plantations of eucalyptus, the most common plantation tree, are already notorious for their devastating social, ecological and climate change impacts. Butnew researchout of Oregon State University is attempting to green these plantations with claims that eucalyptus trees can be genetically engineered to be infertile, through a process to knock out LEAFY, the gene believed to control flower formation. The research claims this would prevent eucalyptus trees from invading native ecosystems, though it does nothing to address the ability of eucalyptus to spread asexually through vegetative propagation.

This new technology also does nothing to address the serious problems caused by industrial plantations of eucalyptus. These impacts,outlined in detail by the World Rainforest Movement, include depletion of fresh water; forced displacement of Indigenous groups, rural communities and subsistence farmers; and catastrophic wildfires. In fact, the addition of GE trees to these plantations could exacerbate known impacts and/or lead to new, unknown and potentially irreversible problems.

Another attempt to green GE trees for the bioeconomy involves the development of treesspecially engineered to store extra carbonas a supposed climate change mitigation tool. But anew article in Yale Environment 360challenges schemes like this that focus on tree planting for climate mitigation. Echoing the findings of the World Rainforest Movement and others, the article reports a growing number of scientists and environmentalists are challenging this narrative on tree-planting. They say that planting programs, especially those based on large numerical targets, can wreck natural ecosystems, dry up water supplies, damage agriculture, push people off their landand even make global warming worse. In addition, they say, Tree planting can distract from the greater priorities of protecting existing forests and reducing fossil fuel use.

The attempts to greenwash genetically engineered trees with their unpredictable and irreversible impacts are beingopposed globally by a broad coalitionof scientists, Indigenous peoples, agronomists, peasant farmers, foresters, teachers and others, as well as organizations focused on protecting forests, human rights and climate justice. GE trees have no place in an ecologically and socially just future.

Authors note:Following the initial publication of this article, Reutersreportedthat a Memorandum of Understanding (MOU) was signed on April 21 between the Eastern Band of the Cherokee Indians (EBCI) and the American Chestnut Foundation. The MOU, described by EBCI members as highly controversial, would allow the planting of GE American chestnuts on Cherokee land.

Anne Petermann is the executive director ofGlobal Justice Ecology Project. She has been working on issues related to protecting forests and defending the rights of Indigenous peoples since 1990 and co-founded the first global campaign against genetically engineered trees in 2000. In the years since, she has presented the social and ecological dangers of genetically engineered trees at conferences, with community groups, and at the United Nations and other international fora on five continents. She currently coordinates theCampaign to STOP GE Trees, which she co-founded in 2014. Follow her on Twitter:@AnneGJEP.

This article first appeared onTruthoutand was produced in partnership withEarth | Food | Life, a project of the Independent Media Institute.

Continued here:
USDA May Allow Genetically Modified Trees to Be Released Into the Wild - NewsClick

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Will USDA Allow Genetically Modified Trees to Be Released Into the Wild? – LA Progressive

Posted: at 11:48 am

On August 18, 2020, the U.S. Department of Agriculture (USDA) published apetitionby researchers at the State University of New York College of Environmental Science and Forestry (ESF) seeking federal approval to release their genetically engineered (GE)Darling 58 (D58) American chestnut treeinto U.S. forests. Researchers claim the transgenic D58 tree will resist thefungal blightthat, coupled with rampant overlogging, decimated the American chestnut population in the early 20th century. In fact, the GE American chestnut is aTrojan horsemeant to open the doors to commercial GE trees designed for industrial plantations.

The D58 would be the first GE forest tree approved in the U.S. and the first GMO intended to spread in the wild. (GE canola plants werediscoveredin the wild in 2010 but that was unplanned.) This is a project to rapidly domesticate a wild species through genetic engineering and accelerated breeding, and then to put it back into ecosystems to form self-perpetuating populationsan intentional evolutionary intervention that has never been attempted before with any species,explainscientists at the Center for Food Safety (CFS) and International Center for Technology Assessment (ICTA), which are nonprofits based in Washington, D.C.

The Southern U.S. is global ground zero for the forest products industry and we see genetically engineered chestnut trees as this industrys sneaky way of opening the floodgates for frankentrees that will harm forests, biodiversity and local communities across the region,explainsScot Quaranda of Dogwood Alliance, a nonprofit based in North Carolina that works to protect Southern U.S. forests. Our natural forests that support wildlife and the economic sovereignty of rural communities will rapidly be replaced with tree plantations for wood pellets, paper and more, leaving environmental and climate injustice in their wake.

A genetically engineered chestnut tree may be the first to spread into forests, setting dangerous global precedents.

The GE American chestnut faces an uphill battle due to decades of opposition to GE trees by Indigenous peoples, scientists, students, activists, foresters and others, including aGE tree ban by the Forest Stewardship Counciland a United Nationsdecisionthat warns countries of the dangers of GE trees and urges use of theprecautionary principlewhile addressing the issue.

By October 19, 2020, the close of the public comment period on the petition,109 organizations, representing millions of members, plus an additional 123,426 individualshad registered their opposition to the D58. The next step is the creation of a draft Environmental Impact Statement (EIS) by the USDA recommending action on the petition. The American Chestnut Foundation (TACF) estimates this could take up to a year to complete. Following this, another public comment period will be undertaken to review the draft EIS, after which the agency will develop a final EIS with a decision on the petition.

While American chestnut trees are known to livehundredsof years, D58 trees have only been growingsince2017, calling into question the ESFpetitionassertion that Darling 58 has been studied in detail and no plant pest or environmental risks have been observed.

In areport on the GE American chestnutshe co-wrote, Dr. Rachel Smolker from Biofuelwatch explains, Given the long lifespan of trees and varying environmental conditions they face, we cannot extrapolate from tests done on very young trees under controlled lab and field conditions. How GE trees might behave in the diverse and changing context of natural forests over long periods of time is unknown and likely to remain unknown even after they are released.

Scientists at CFS and ICTAwarn ofproblems with the D58 safety studies,writing, Given the young age of Darling 58 trees and corresponding dearth of tissue samples, conclusions from most of the animal experiments described in the Petition are too preliminary to depend upon.

In studying ESFs assessment of the impacts of inserting the blight-resistant oxalate oxidase (OxO) transgene into the chestnut genome, both CFS and ICTA furtherpoint outthat some D58 studies did not, in fact, use material from transgenic D58 trees, rendering them invalid. Petitioners did experiments to study how bumblebees might be affected by Darling 58, but did not have enough Darling 58 pollen for the experiments so used non-transgenic pollen instead, to which they added purified OxO from barley seeds. Other important initial studies on animals reported in the Petition are of limited use because they involved feeding leaves from the Darling 4 instead of Darling 58 even though Darling 4 has much lower levels of OxO in leaves again invalidating the conclusions for risk assessments. The Darling 4 was an earlier version of the American chestnut genetically engineered with the OxO transgene.

While researchers have argued that a strict regulatory process will ensure the safety of the D58 GE tree, a 2019 report by the National Academies of Sciences, Engineering, and Medicine titled, Forest Health and Biotechnology: Possibilities and Considerations, raises flags: Forest health is not accounted for in the regulations for the use of biotechnology or for other approaches to mitigating forest tree insect pests or pathogens. There are no specific regulations or policies that those agencies apply to biotech trees.

Proponents argue that there can be no downside to releasing a tree engineered to resist an introduced blight. But like fire suppression, which has led to devastating wildfires due to an unnatural buildup of flammable materials in the forest, the future impacts of even a well-meaning action can become catastrophic, especially in combination with the unpredictable effects of climate change and extreme weather. Yet, researchers are engineering trees with the conviction that because they can, they should.

In her bookCan Science Make Sense of Life?, Dr. Sheila Jasanoff, Pforzheimer Professor of Science and Technology Studies at the Harvard Kennedy School, explains the implications of this arrogance. For life scientists and their enthusiastic promoters, the arc of the technologically possible, often coincident with the promise of financial gain, increasingly defines the boundaries of the morally permissible.

Researcher William Powell, whose GE American chestnut research hasreceivedboth financial and technical support from companies with a vested interest in the approval of the GE American chestnutincluding Monsanto, ArborGen andDuke Energydefendshis approach. In an article in the Conversation, Powell says, One of the key advantages of genetic engineering is that its far less disruptive to the original chestnut genomeand thus to its ecologically important characteristics. The trees remain more true to form with less chance of unforeseen and unwanted side effects. Once these genes are inserted, they become a normal part of the trees genome and are inherited just like any other gene.

However, in a briefing paper published by the Federation of German Scientists, Dr. Ricarda Steinbrecher, a molecular geneticist, and Antje Lorch, a biologist, counter that the genetic engineering process is inherently risky. Thepaperstates, It is well documented that the processes of plant transformation give rise to many mutations throughout the plant genome as well as at the insertion site of the transgene. Any robust risk assessment study needs to take several generations into account, for example to assess the stability and heritability of the transgene, unintended side effects and changes due to transformation impact.

The D58 American chestnut is the culmination of decades of effort to open the doors to GE trees in the U.S. by biotechnology and timber companies. In 1999, Monsanto joined with timber companies from the U.S. and New Zealand to form a forestry biotechnology joint venture, which later became ArborGen, one of the worlds leaders in GE tree research and development. GE tree research was originally focused on trees and traits valued by the forest products industry; trees like poplar, pine and eucalyptus, and traits like insect resistance, herbicide tolerance, faster growth or altered wood composition.

Other early associationsincluding theTree Genetic Engineering Research Cooperativeat Oregon State University, launched in 1994brought together university researchers with timber and biotechnology giants as well as the U.S. Forest Service to develop genetically engineered trees for industrial timber plantations.

These efforts were met with widespread opposition and sabotage, leading the industry to conclude that they needed a charismatic test tree to try to win over the public opinion relating to GE trees.

A 2007published paperexplains, There is opposition to commercial application of trees, engineered specifically for fast growth and increased yields, by those whose stance is that the value accrues only to big companies. It will remain for traits that have broad societal benefits, such as conservation for acceptance to be gained.

The D58 is seen as a positive example for the beleaguered biotechnology industry of the benefits of biotechnology for conservation. Duke Energy also sees the American chestnut for its value as a greenwashing tool. Duke Energy invested millions into the GE American chestnut through theForest Health Initiative. Its hope was to use the American chestnut to help green its devastated mountaintop removal mining lands.

Naturalist and author Bernd Heinrich has one such grove growing on his land in Maine. In aNew York Times op-edin 2013, he wrote, I have been enjoying American chestnuts for several years now, harvested from some trees that are now part of my forest of 600 acres in western Maine. I planted four seedlings in the spring of 1982. Beyond all my expectations, the trees thrived, and some are now 35 feet tall. In my small corner of western Maine, the American chestnut is now promising to again become a significant component of the ecosystem.

Once dominant in Eastern U.S. forests, the American chestnut was highly valued for its beautiful and rot-resistant wood, and abundant nuts. While few actually remember the tree, which largelydisappearedfrom the landscape by the 1920s, a public relations effort was launched in the early 2010s with articles appearing in numerousmajor publicationsheralding the return of this mighty giant through the wonders of genetic engineering.Millions of American chestnut stumps, meanwhile, continue to send up shoots that occasionally grow into trees large enough to produce nuts, and in some locations, wild American chestnuts are spreading on their own, showing at least some evolving blight tolerance.

Another decades-long program by theAmerican Chestnut Cooperators Foundationis successfully breeding pure wild American chestnuts that are naturally blight-resistant.

In spite of examples like this, GE chestnut proponents have declared the American chestnut functionally extinct, and insist that itssurvivalhinges on the release of unproven and risky genetic engineered American chestnut trees into forests. But Lois Breault-Melican, a former board member of the American Chestnut Foundation whopublicly resigned from the TACFover the organizations support for the GE American chestnut, points out that this argument ignores the risks posed to organic and other chestnut growers: These growers are concerned about the potential GMO contamination of their orchards caused by the unregulated and unmonitored planting of genetically engineered American chestnut trees. If theUSDA approves these GE American chestnuts, the integrity of chestnut orchards would be forever compromised.

Indigenous peoples in the regions of proposed D58 releases have expressed concern that unregulated distribution of a GE tree would violate their sovereign right to keep their territories free from GMOs. They insist that Indigenous peoples be consulted in theprocessof reviewing the D58 American chestnut.

Today, there remain large areas of traditional and treaty lands on which much is forested and managed as sovereign territory of many different Native American Peoples,explainsBJ McManama of the Indigenous Environmental Network. These forests are not only a source of economic self-determination but hold great cultural significance to include sacred sites where trees are an element of sustenance, knowledge and familial identity. Every living being within the forests [is] related in some form and nothing within these lands lives in isolation; therefore, changing or altering the original instructions of any one or any part of these elements threatens the natural order established over millennia.

The Eastern Band of Cherokee, members of the Lumbee Tribe of central North Carolina and Seminole Peoples from unceded Florida territory joined the Campaign to STOP GE Trees foran October 2014 gatheringin the mountains of North Carolina to protest GE trees as a form of colonization. Their concerns were focused on the GE American chestnut trees.

Lisa Montelongo, a member of the Eastern Band of the Cherokee,explained, Im very concerned that GE trees would impact our future generations and their traditional uses of trees. Our basket makers, people that use wood for the natural colors of our clay workthere would be no natural life, no cycle of life in GE tree plantations.

Following the camp, the Bands Tribal Council passed a unanimous resolution prohibiting GE trees from their lands: Eastern Band of the Cherokee Indians (EBCI) Tribal Council Resolution No. 31 (2015): We commit to rejecting biomass, genetically engineering the natural world, carbon trading, carbon offsets and carbon sequestration schemes as they are false solutions to the climate change. Concerns were focused on the inability of the tribe to keep the GE American chestnut tree off of their lands if it were released into surrounding forests, which they describe as a violation of the Free, Prior and Informed Consent mandate under theUNs Declaration on the Rights of Indigenous Peoples.

In the end, the potential deregulation of the D58 is not about restoring a mighty giant to Eastern U.S. forests. Its approval is about paving the way for the deregulation of all GE trees, toward the creation of an oxymoronic future bioeconomy where biodiverse forests are replaced with specially engineered trees for the manufacture of fuels, chemicals, textiles, plastics and other goods in a green version of business as usual. Implicit in this scheme is a massive increase in the consumption of wood. This in turn will drive accelerated conversion of carbon-rich native forests, critical for climate regulation, and other ecosystems for conversion to fast-growing plantations that include GE trees with traits to expedite their use as feedstocks. Existing non-native plantations of eucalyptus, the most common plantation tree, are already notorious for their devastating social, ecological and climate change impacts. Butnew researchout of Oregon State University is attempting to green these plantations with claims that eucalyptus trees can be genetically engineered to be infertile, through a process to knock out LEAFY, the gene believed to control flower formation. The research claims this would prevent eucalyptus trees from invading native ecosystems, though it does nothing to address the ability of eucalyptus to spread asexually through vegetative propagation.

This new technology also does nothing to address the serious problems caused by industrial plantations of eucalyptus. These impacts,outlined in detail by the World Rainforest Movement, include depletion of fresh water; forced displacement of Indigenous groups, rural communities and subsistence farmers; and catastrophic wildfires. In fact, the addition of GE trees to these plantations could exacerbate known impacts and/or lead to new, unknown and potentially irreversible problems.

Another attempt to green GE trees for the bioeconomy involves the development of treesspecially engineered to store extra carbonas a supposed climate change mitigation tool. But anew article in Yale Environment 360challenges schemes like this that focus on tree planting for climate mitigation. Echoing the findings of the World Rainforest Movement and others, the article reports a growing number of scientists and environmentalists are challenging this narrative on tree-planting. They say that planting programs, especially those based on large numerical targets, can wreck natural ecosystems, dry up water supplies, damage agriculture, push people off their landand even make global warming worse. In addition, they say, Tree planting can distract from the greater priorities of protecting existing forests and reducing fossil fuel use.

The attempts to greenwash genetically engineered trees with their unpredictable and irreversible impacts are beingopposed globally by a broad coalitionof scientists, Indigenous peoples, agronomists, peasant farmers, foresters, teachers and others, as well as organizations focused on protecting forests, human rights and climate justice. GE trees have no place in an ecologically and socially just future.

Anne PetermannIndependent Media Institute

This article first appeared onTruthoutand was produced in partnership withEarth | Food | Life, a project of the Independent Media Institute.

Authors note:Following the initial publication of this article, Reutersreportedthat a Memorandum of Understanding (MOU) was signed on April 21 between the Eastern Band of the Cherokee Indians (EBCI) and the American Chestnut Foundation. The MOU, described by EBCI members as highly controversial, would allow the planting of GE American chestnuts on Cherokee land

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Will USDA Allow Genetically Modified Trees to Be Released Into the Wild? - LA Progressive

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