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Energy & environment research – Open Access Government
Posted: June 28, 2021 at 9:55 pm
Dr Sanju A. Sanjaya received a PhD in 2003 from the University of Mysore, Mysore, India, on tree improvement and biotechnology. That same year, he joined the Agricultural Biotechnology Research Center at Academia Sinica, in Taipei, Taiwan as a postdoctoral fellow working on the genetic engineering of orchids and tomatoes, for biotic and abiotic stress tolerance. He has worked at the Great Lakes Bioenergy Research Center at Michigan State University as a Senior Research Associate on a project focused on increasing energy density in vegetative tissues. His credentials include three patent applications, 20 papers in refereed journals, six published book chapters and eight published reviews.
Dr Sanjayas lab leads an active research program to design photosynthetic organisms with enhanced bioenergy and industrial compounds for higher production, profitability and sustainability. Dr Sanjayas research group uses bioinformatics, biochemical, molecular, cell biology and genetic engineering approaches to understand the primary metabolism mechanisms in plants and microalgae. Dr Sanjayas lab also aims to advance the use of photosynthetic organisms to address water quality issues and phytoremediation.
The West Virginia State University Energy and Environmental Science Institute (WVSUEESI) mission is to conduct basic and applied interdisciplinary research in energy and the environment to generate technology and knowledge.
Our goal is to partner with public and private sectors, so we can work together to address pertinent energy and environmental issues for West Virginia, says WVSUEESI Director, Dr Sanjaya. Those issues include researching the feasibility and sustainability of alternative energy sources for the Mountain State as government regulation and environmental concerns continue to cast resources such as natural gas and coal in the national spotlight.
Those new energy sources include renewable resources from plant-based biomass. Scientists at WVSU conduct ongoing projects focusing on feedstock improvement, biofuels and bioproducts; genomics; bioremediation, environment and sustainability. One project involves increasing the production of plant oils in the biomass of bioenergy crops that can be used to produce biodiesel and replanted onto formerly mined areas to determine how well crops will grow on reclaimed land.
One of the goals of the WVSUEESI is to generate technologies and provide hands-on research opportunities to students and science-based outreach opportunities for K-12 youth; Research and Teaching Graduate Assistantships in the MS Biotechnology Program; the Research Rookies Program in energy-related research; Agricultural and Environmental Science Careers for Non-Traditional Students (AESCONTS) throughout the region in the hope of generating the tomorrows scientists.
Ive always wanted to progress professionally and academically and to enrich my previous experience working with energy and environmental science, Dr Sanjaya explains. One of my biggest interests in being at WVSU is the opportunity to work in a team, with hard-working and smart students and scientific community.
Dr Sanjaya hopes the research will ultimately attract industry and academic partners to the region, enhancing economic development and workforce opportunities.
In addition to his ambitious research, Dr Sanjaya is a true leader in the classroom at WVSU who enjoys interacting with and motivating his students. He goes on to provide further detail: I often bring my students to the lab to do the real work theyre learning about in the classroom. Its a different opportunity for learning because my research is very hands-on.
Ever the visionary, Dr Sanjaya not only hopes his research will motivate West Virginians to stay in the State, but he looks forward to the day that young people will flock to West Virginia to work in science and research.
Dr Sanjaya adds: If my research is even a small piece of the puzzle that helps West Virginia, then I am happy.
As we enter an era where global food production is likely to double as the human population increases, sharing prime agricultural lands and resources for food and energy production becomes an even greater challenge. A breakthrough technology that enables the cultivation of an energy crop on a vast area of marginal lands can address these issues. Dr Sanjaya uses a gene-editing technique called CRISPR that gives him the ability to alter genes in plants, enabling them to grow on mountainous terrain, in soil with low nutrients, and even under drought conditions. This research is considered cutting edge, but has already proven viable in other parts of the world.
Dr Sanjaya then turns the discussion towards current research when it comes to improving the nutritional and energy content of crops. Dr Sanjaya considers why this is necessary for society today and how this incorporates gene technology.
Currently, the majority of the oils used in biodiesel production come from the seeds of plants, Dr Sanjaya comments. Biodiesel is a form of diesel fuel derived from plants or animals. By increasing the energy provided by plants, the land required to grow both biodiesel and food crops could be significantly reduced, he adds.
Plants accumulate oils within the tissue of the seeds to help with the energy-intensive process of germination and growth of new seedlings. By harnessing the mechanism used by the plant to send and store these oils within the seeds, Dr Sanjaya and his team aim to create new breeds of plants that accumulate higher amounts of oils within the rest of the plants vegetative tissue the leaves, stems and roots.
To increase the amount of oils stored in the vegetative tissue of plants, Dr Sanjaya and his colleagues have taken a two-pronged approach. Plants can only capture a finite amount of carbon in any period, so increasing the amount of oils created and stored necessarily requires a reduction in the amount of starch being produced.
First, the researchers used advanced molecular techniques to manipulate the genes involved in producing and accumulating oils called triglycerides using the model plant Arabidopsis thaliana. This flowering plant species is related to mustard, cabbage and radishes and is ideal for testing and refining genetic techniques because of its small size and short generation times.
By increasing the activity of a gene controlling seed oil production, Dr Sanjayas team created a version of the plant that tends to store these oils within the vegetative tissue.
Following this, the team focused on a gene involved in starch production. They found that when this gene was edited to exhibit decreased activity, more carbon was left available to be routed into the production of oils. The resulting plant that possesses both edited genes divides more of the carbon captured during photosynthesis into oils than into starch.
Our long-term goal is to develop energy-dense bioenergy crops that can grow on vast areas of reclaimed coal mine lands of West Virginia and the Appalachian coal basin, Dr Sanjaya comments.
Ultimately, he says, this work could bring sustainable agriculture and sustainable energy-related industry to the State.
FUNDING: USDA NIFA and NSF RIA
Please note: This is a commercial profile
2019. This work is licensed under aCC BY 4.0 license.
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Genetic Engineering Plant Genomics Market- Investment Opportunities With Recent Trends, COVID-19 Impact And Top Players Revenue- Eurofins Scientific,…
Posted: at 9:55 pm
The report on Genetic Engineering Plant Genomics Market aims to provide introductions of the market With latest launches, recent mergers, collaboration with others for promoting the product recently launched, their market revenue and valuation in different regions.The report analyses and evaluates the important industry trends, market size, market share estimates, and sales volume with which Genetic Engineering Plant Genomics industry can speculate the strategies to increase return on investment (ROI). This business report presents comprehensive explanation of market definition, market segmentation, competitive analysis and key developments in theGenetic Engineering Plant Genomics industry.
Competitive Landscape :
The report mentions various industry leaders focusing on researches for maintaining their leading position in the market post pandemic.The report provides snapshots and briefings of key strategies of the companies, which products they offer, their dominating regional presence, their competitors, and their strategies to grow post COVID-19 due slow growth expected by experts. Furthermore, the report also mentions the key growth insights, companies market presence, years of operations, technological aspects, financial strength, geographical presence, etc. Thus, with the report, the market players and stake holders get an outlook about the developing companies for investment opportunities help build their assets.
Market Overview:
Genetic engineering plant genomics refer to the process of development of new plant lines with enhanced genotypic characteristics by crossing two or more plants with the purpose of producing an offspring that shares the required traits of the parent plants. The aim of the method is to characterize, sequence and study of genetic compositions, functions and networks of entire plant genome. The technological advancement is emerging with the increasing demand for better-quality crops.The genetic engineering plant genomics market is expected to witness market growth at a rate of approximately 7.90% in the forecast period of 2021 to 2028. Data Bridge Market Research report on genetic engineering plant genomics market provides analysis and insights regarding the various factors expected to be prevalent throughout the forecast period while providing their impacts on the markets growth. The increasing application of genomics in plant breeding across the globe is escalating the growth of genetic engineering plant genomics market.The increasing demand for improved crop varieties and high quality crop, and surge in plant genome funding fueling the adoption of innovative technologies act as the major factors driving the genetic engineering plant genomics market.
Download Free PDF Sample Report (Including COVID-19 effect Analysis) @https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-genetic-engineering-plant-genomics-market
Key Insight of The Report:
Top Players In Genetic Engineering Plant Genomics Industry :
The major players covered in the genetic engineering plant genomics market report are Eurofins Scientific, Illumina Inc, NRGene, Neogen Corporation, Agilent, LC Sciences.LLC, Traitgenetics GmbH, Keygene, Novogene Co.Ltd, GeneWiz, BGI, Genotypic Technology, ADAMA, Bayer AG, UPL, Corteva, Zhejiang Xinan Chemical Industrial Group Co., Ltd, Nufarm, DuPont, Syngenta AG, VILMORIN & CIE, Corteva, SUNTORY HOLDINGS LIMITED among other domestic and global players. Market share data is available for global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.
KeyQuestions Answered By Report:
Get More Insight Before Buying @https://www.databridgemarketresearch.com/inquire-before-buying/?dbmr=global-genetic-engineering-plant-genomics-market
Table of Contents of Genetic Engineering Plant Genomics Market Report:
Executive Summary
Market Landscape
Five Forces Analysis
Market Segmentation by Product
Geographic Landscape
Vendor Analysis
Appendix
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Mapped: Happiness Levels Around the World in 2021 – Visual Capitalist
Posted: at 9:55 pm
Are you happy? is a deceptively complex question to both ask and answer.
Its generally understood that having enough money to cover your needs and wants can help you live a relatively happy, comfortable lifeand recent research shows this relationship may increase linearly as income levels grow, as well.
However, theres much more to it than that. Happiness levels depend not just on financial security, but also broader perceptions of ones social support, personal freedom, and more.
This series of map pulls data from the World Happiness Report to uncover the average scores of 149 countries between 2018-2020, and which ones emerged the happiest or unhappiest. We also look at the most and least improved countries in every region.
First, lets look at the factors used to calculate world happiness levels. Some clear indicators are health and wealth, both metrics that have been steadily on the rise worldwide. The report takes these into account, weighting GDP per capita and life expectancy at birth into the scores.
The report also looks at more intangible aspects, collecting survey responses around:
This year, there was a natural focus on the negative affect measure of the COVID-19 pandemic on happiness levels, such as exacerbating mental health risks. In addition, such measurements varied depending on each countrys response to the crisis.
Worldwide happiness comes in at an average score of 5.5, a marginal improvement since our previous coverage of this report in 2019. Lets dive into regional outlooks for happiness levels.
Current Mood: Happy (6.1)
Canada retains its spot as the happiest country in North America, although its overall global ranking has dropped over the years. In 2019, it was ranked in ninth place globally, dropping to 11th in the 2020 edition, and declining further to 14th place in this years report.
Haiti continues to fare poorly as the unhappiest in the region, with an average annual GDP growth of only 1.3% over 20 years. Its weak economy and political instability have been worsened by the pandemicsetting back efforts to reduce poverty and widening inequality.
Current Mood: Content (5.9)
With the largest middle class in the Americas60% of its populationand a miniscule 0.1% extreme poverty rate, Uruguay is the happiest South American country. The nation has also achieved equitable access to basic services, from education to electricity.
The trio of Colombia, Ecuador, and Venezuela are experiencing different stages of progress in happiness levels, but their relationship is very much interdependent.
Venezuela and Ecuador face similar economic challenges and sharp declines in oil prices. Venezuela is additionally acutely affected by socio-political unrest, triggering a mass exodus of citizens to Ecuador and Colombia alike. The silver lining is that the influx of highly-educated Venezuelan migrants may provide a 2% boost to Ecuadors GDP.
Colombia, the most improved country, has halved its poverty rate in the last decade. In addition, it has welcomed almost 2 million Venezuelan migrants as of Dec 2020and plans to provide them up to 10 years of protective status.
Current Mood: Happy (6.4)
Finland remains at the top of the leaderboard as the worlds happiest country. This years ranking was also influenced by high levels of trust in the way the COVID-19 pandemic was handled.
Meanwhile, the shock of the COVID-19 crisis is expected to be short-lived in Croatia, which is the most improved country. This is partly due to its steady pre-pandemic economic gains, although risks remain.
In the unhappiest country of Ukraine, conflicts continue to cause stress on its politics, security, and economy. In particular, government corruption remains a big public issue.
Current Mood: Its Complicated (5.3)
Saudi Arabia is the most improved country in the region, as it continues to reduce its oil dependence, diversify its economy, and bolster its public services. It has also been making some progress towards gender equality.
The tourism and hospitality industries contribute nearly 20% of Jordans GDPand COVID-19 has caused a prolonged economic decline in the country along with the headwinds of these industries.
Although Afghanistan has seen improvements in access to basic services and its agricultural economy, challenges remain with prolonged conflict and violence. A post-pandemic recovery in the worlds unhappiest country might take several years.
Current Mood: Neutral (5.5)
Both New Zealand and Taiwan saw a successful COVID-19 response and recovery boosting their positions in the global happiness rankings. In fact, New Zealand was the only non-European country to make it into the top 10 on the global happiness list.
Note: As the report only covers 149 countries, Oceania only refers to Australia and New Zealand in this instance.
Although India remains the unhappiest country in the region, it also showed the most improvement overall, possibly due to its increased access to basic services. Notably though, the pandemic caused a sharp economic contraction in real GDP by 23.9% year-over-year in Q12021.
Current Mood: Unhappy (4.5)
In July 2020, the island nation of Mauritius joined Seychelles to become the second high-income country in Africa, helping cement its status as the happiest in the region.
Zambia, the most improved African country, has one of the worlds youngest populations by median agewhich presents long-term opportunities for labor force participation.
On the flip side, agriculturally-reliant Benin struggles with high poverty, with close to 40% of the population living below $1.90 per day.
Zimbabwe, the unhappiest country, has been through not just natural disasters but financial disasters too. It experienced hyperinflation of 786% in May 2020, accompanied by an equally sharp rise in food prices.
Although each country has been uniquely impacted by the pandemic, its clear that on the whole, happiness levels take into account so much more. How will future rankings look like in a post-pandemic world?
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Passing on the good beetle genes – Cosmos Magazine
Posted: at 9:55 pm
Turns out, males do have a purpose and yes, it is about sex.
According to a new study, published in Evolution Letters, the male seed beetle helps purge bad mutations and retain good genes through strict competition and sexual selection, increasing the long-term genetic health of a population.
The researchers, led by Karl Greishop of the University of Toronto, Canada, studied 16 genetic strains of the seed beetle (Callosobruchus maculatus) in an intensive breeding program to see how deleterious mutations ones that wont kill you, but might affect health and ability to reproduce affected both males and females.
They found that deleterious mutations affected males more than females, but that this actually increased the genetic population as a whole.
Our study shows that production of males, which may engage in intense competition for the chance to mate, enables faster purging of deleterious mutations from the population, which could thereby enable a healthier set of genes and higher reproductive capacity relative to asexual reproduction, says David Berger of Uppsala University, Sweden.
Read more: The long-term effects of sexual competition
In essence, male beetles with stronger genes outcompeted the males with bad mutations, which were unable to have as many babies and couldnt pass on bad beetle genes that well. The same effect wasnt seen in females, which had just as many babies and were able to pass on deleterious mutations.
This indicates that although these mutations do have a detrimental effect on females reproduction, they are more effectively removed from the population by selection acting on male carriers rather than female carriers, says Grieshop.
Previous research from our group and others has succeeded in showing this effect by artificially inducing mutations, but this is the first direct evidence that it ensues for naturally occurring variants of genes.
That meant that male beetles were responsible for purging bad genes from the mutations, purely because they couldnt pass them on, and the genetically stronger male beetles ended up impregnating more female on their behalf, without the population diminishing.
Read more: Water beetles mate to an evolutionary standstill
When deleterious mutations are purged from a population through rigorous selection in males, resulting in fewer males reproducing, the process can take place with little or no effect on population growth, says Greishop.
This is because relatively few males suffice to fertilise all the females in a population, hence whether those females are fertilised by few males or many males makes little or no difference to the number of offspring those females can produce, especially in species where the male doesnt look after its own offspring.
By contrast, such rigorous selection in females would result in fewer females reproducing, hence fewer offspring produced, which could lead to a massive population decline or even extinction.
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Meacham: Oklahoma has long exhibited the DNA of entrepreneurship – Oklahoman.com
Posted: at 9:50 pm
By Scott Meacham| Oklahoman
Of the nearly 3 billion base pairs in the human genome, about 99% are the same in every human being however, it is the sequence of these DNA pairs that makes each of us who we are genetically.
Its like that with entrepreneurial DNA every state has it.
Our country was built by entrepreneurs. Its just that from state to state, our DNA is sequenced differently.
In Oklahoma, our entrepreneurial DNA isnt channeled from one dominant industry or from a particular type of entrepreneur. Our state heroes of innovation have impacted industries across the board from human flight to rock and roll. From changing the way that people drive to changing the way the way people exercise. From making it easier to shop to making it easier to park. From digging ditches to accessing the Internet.
Wiley Post, the aviator with the vision of moving people and freight faster over greater distances, envisioned space travel and, in 1934, invented the pressure suit and advanced innovation in airplane design and fuel forever linking our state to the moon and Mars.
While Wiley Post was pushing the limitations of flight, Oklahoma musician and electric guitar pioneer Bob Dunn was doing some soaring of his own. Dunn carved a place in the history of country swing, during a two-day recording session of 30 one-take cuts, making the first recording of music on an electric guitar, which was his self-engineered electric instrument.
Tulsa state patrol officer Clinton Riggs invented a funny-shaped sign with just the word yield that, without changing laws or the construction of intersections and access ramps, reduced accidents and saved lives.
Nautilus inventor Arthur A. Jones built his first exercise machine while living at the Tulsa YMCA.
Grocer Sylvan Goldman created the shopping cart so that his Oklahoma City customers could buy more on each trip to the grocery store the icon in the upper corner of your Amazon page is the icon of Sylvans legacy.
Another icon invention, Carl Magees parking meter, improved traffic flow and access to parking in Oklahoma City and in all other 49 states.
The Malzahn family, of Ditch Witch fame, gave the world a whole new way to install underground utilities safely and efficiently from gas, electric, and plumbing in the 1950s to telecommunications, CATV, and fiber options today.
Edward Roberts in 1974 invented the first personal computer that attractedPaul Allen and Bill Gates, who then wrote Altair BASIC, the first high-level coding language which became the first product of Microsoft, and the foundation upon which Gates and Allen eventually built the largest software company in the world.
DNA was discovered in 1869 when Swiss biologist Friedrich Miescher found an odd substance that didnt match the proteins he expected in his research of white blood cells. It took another 100+ years, extensive Nobel-caliber research, and groundbreaking advances in computer technology and nuclear medicine to gain the understanding we have today of DNA.
Just as human development is built on the hereditary material of DNA, so is Oklahomas path of innovation and construction of the entrepreneurial DNA of our state. With pride and determination, we need to continue to build on our amazing history of commercializing great ideas that happen here.
Scott Meachamis president and CEO of i2E Inc., a nonprofit corporation that mentors many of the states technology-based startup companies. i2E receives state support from the Oklahoma Center for the Advancement of Science and Technology and is an integral part of Oklahomas Innovation Model. Contact Meacham at i2E_Comments@i2E.org.
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Meacham: Oklahoma has long exhibited the DNA of entrepreneurship - Oklahoman.com
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How Drones And DNA Can Drill Down To The Past – WVXU
Posted: at 9:50 pm
Earlham College researchers have returned to Iceland with a variety of tech tools to help Icelanders learn more about their Nordic past.
Computer scientist Charlie Peck and biologist Emmett Smith have spent a month at the end of a long peninsula on the east coast of Iceland. Peck explains if you were to drop a stick in the ocean in Norway, the currents would likely bring that stick near the sites where they are working with Icelandic archaeologists.
Peck and Smith are doing what they call 21st century science. Examining the past not only requires archaeologists, but computer scientists using drones to locate where to dig and biologists to identify DNA found in the environment, particularly soil.
The National Geographic Society is funding the project looking at some of the earliest Viking settlements in Iceland in the year 875.
Peck, Smith and the archaeologists want to know what was there and what the people were doing there.
According to Smith, "If I take a soil sample, extract DNA, are we going to find things like particular whole species or fish species that we know they would be consuming? Are we going to see sheep we know they were husbanding? Do we have dogs, horses and cattle which are not in Iceland natively?"
Peck pulls up a picture during our Zoom interview that shows very dark soil. That's the fire pit his drone, guided by computer software, picked up in a giant field.
"You'll fly and pick out features through the change in surface plants that tells you to dig here," he says.
They are also creating a 3D map in a river valley to measure erosion. Climate change is more pronounced in Iceland than in the Midwest and the scientists, when comparing their map to a British-made one in 1942, can determine how nature moves in as the glacier recedes. Microbes in the soil are also useful in determining this.
Smith has dozens of soil samples but moving them across international borders isn't easy. They will use a series of techniques and specialized tools to extract the DNA from the soil samples and store it in tubes. "Then we just come back with a hundred 1.5 ml tubes on frozen vegetables - to keep them cold - and bring those back to Indiana to do the sequencing and the analysis on."
What Have They Found?
Archaeologists discovered a Roman coin which could mean the site was once a trading post.
Smith focuses on the DNA found in soil.
"The henbane and the cranberry in particular indicate that we are seeing ancient DNA that was brought to this location in the form of plant material by the settlers. We've not yet found any human DNA. That was our goal. But every year the technology (and) the analysis tools get better."
Yujeong Lee is telling Earlham's story on the Earlham Field Science Instagram account.
Blog:https://fieldscience.cs.earlham.edu/andhttps://fieldscience.cs.earlham.edu/index.php/blog-2021/
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Man charged with sexual battery in 14-year-old cold case after entering his DNA into ancestry website – WRAL.com
Posted: at 9:50 pm
By Maggie Brown, WRAL multiplatform producer
Tampa, Fla. A Florida man was charged with sexual battery in relation to a cold case that happened in 2007. Police used genetic genealogy testing to find Jared Vaughn, 44, after he submitted his DNA to the genealogy website, FamilyTreeDNA.
In 2007, a woman was assaulted after a man offered to drive her home. At that time, a sexual assault kit was done to try and identify the woman's attacker, officials said.
A crime lab used GEDmatch and FamilyTree's DNA databases to identify Vaughn as a possible suspect, according to authorities. A warrant was obtained and officials gathered a swab from Vaughn, to confirm that his DNA matched what was in the kit.
Police have used DNA from online genealogy sites to solve dozens of cold cases, according to Pew Research.
According to a survey from June, 48% of people said they were OK with DNA testing companies sharing data with police. A third said it was unacceptable, and 18% were unsure.
The website officials say Vaughn used, FamilyTree, only allows law enforcement to use its site to solve homicides, sexual assault or abduction cases.
Experts say that even if someone did not use a genealogy website, their DNA could still be retrieved. Someone's third cousin's DNA profile on FamilyTree could be used by law enforcement in an investigation, according to Nia Bala, a senior attorney at the Policing Project at New York University Law School.
"I click the box and say, yes, law enforcement can use my information. That feels above board," she told Slate. "But what about my third cousin? Do they know that their information essentially is out there as well, because my DNA and their DNA are linked?
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Sex, lies and DNA: why many ‘Bothas’ in South Africa have the wrong surname – The Conversation CA
Posted: at 9:50 pm
Headlines about molecular genetics being used to shed new light on old mysteries or even put criminals behind bars have become increasingly more common.
In South Africa DNA is being used to answer important questions about everything from a group of peoples origins to the biological paternity of a child.
But paternity tests arent just applicable to modern cases. Fellow researcher Christoff Erasmus and I considered DNA evidence to understand a divorce case dating back 321 years. The events before and after the divorce case of Maria Kickers had long-term consequences for a family with a surname that, for decades, appeared often among the countrys white leaders. That name is Botha.
The first prime minister of the Union of South Africa, established in 1910, was Louis Botha. There was also PW Botha, the last prime minister to hold that title, and the first to become executive state president of the Republic of South Africa.
Our research shows that Kickers lied in her 1700 divorce case at the Cape of Good Hope. Her lie about the paternity of her children led to a chain of events that affected the Botha lineage, resulting in 38 000 people carrying that name when in fact they were descendants of Ferdinandus Appel.
The genetic evidence, which we gathered using a DNA-based paternity test kit, in combination with the documented testimonies, suggests that Ferdinandus Appel was likely the father of Kickers first son and Frederik Botha the father of the other boys. When we genotyped a random sample of Botha males. We found that almost half of them have the Appel rather than the Botha Y chromosome.
The false paternity claim means that tens of thousands of Bothas more than 76 000 South Africans had this surname in 2013 should in fact be called Appel, a very uncommon name in the country.
If the Kickers divorce case was heard today, DNA evidence would have refuted the lie about paternity outright and the Botha family may well have shattered. Our findings provide another reminder that DNA evidence can clarify events that happened centuries ago, deepening and improving our understanding of history.
One of our sources was a set of records presented by Richard Ball, who is linked to the families at the heart of the divorce case. We also drew information from published genealogical records.
From these we pieced together the following events.
Kickers married Jan Cornelitz in 1683 at the Cape. They had seven children four boys and three girls. Christening records for six of these children have been located; all named Cornelitz as the father. In 1700 Jan filed for divorce, claiming that Maria cheated on him with Ferdinandus Appel as well as a tenant who farmed alongside him, Frederik Botha.
Maria denied any involvement with Ferdinandus Appel, but confessed that Frederik Botha was the biological father of all her children.
In her own defence, she claimed that Jan, her husband, encouraged her relationship with Frederik Botha because Jan was onbequaamd a Dutch word meaning incompetent.
Frederik Botha confirmed before the court Marias claim that all her children were his. While the court did not find Maria to be licentious, they did not give her permission to remarry. As a result, Maria and Frederik Botha had to wait until Jan died, 14 years later, before they could marry. The children then took on the name Botha.
Y chromosomes are inherited like surnames. So, any of Marias sons descendants along an unbroken line of males should carry identical Y chromosomes, bar a few mutations.
With the help of a genealogist we managed to contact and obtain DNA samples from all four of Marias sons along unbroken male lines. In three cases, more than one descendent was found. We genotyped these Bothas Y chromosomes with a kit that is used for paternity tests. The Y chromosomes clearly separated into two groups distinguished by too many mutations to have stemmed from the same Botha ancestor. Within each group, there were a few mutations between individuals, as one would expect for two Y chromosomes with 11 to 19 ancestors between them.
Interestingly, the one group linked to Marias first-born son, whereas the other sons descendants all shared virtually identical genetic profiles. This pattern piqued our curiosity as it suggested that the first sons profile may have stemmed from Ferdinandus Appel.
To test this idea, we genotyped two Appel men: one was a clear match to the first sons descendants. It is 130 times more likely that Marias first son was fathered by Ferdinandus Appel than by a random male that just happened to have the same Y chromosome profile
When we genotyped a random sample of Bothas we found that almost half of them have the Appel rather than the Botha profile. To understand why the first son seems to account for more than a quarter of modern Bothas, we looked at the male descendants as listed in the genealogical records published by the now-closed Genealogical Institute of South Africa.
Just counting the 62 males that were 30 years old or younger in 1780, 45% descended from the first brother while the other three Botha brothers accounted for the remaining 55%. The high number of the first brothers descendants in 1780 could thus explain why so many of our random sample grouped with the Appel profile.
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Sex, lies and DNA: why many 'Bothas' in South Africa have the wrong surname - The Conversation CA
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Breakthrough allows scientists to determine the age of endangered native fish using DNA – The Conversation AU
Posted: at 9:50 pm
Identifying the age of animals is fundamental to wildlife management. It helps scientists know if a species is at risk of extinction and the rate at which it reproduces, as well as determining what level of fishing is sustainable.
Determining the age of fish has been difficult in the past primarily involving extracting the inner ear bone, also known as the otolith. Layers of growth in the otolith are counted like rings on a tree to reveal an individuals age. Unless a dead specimen is available, this method requires killing a fish, making it unsuitable for use on endangered populations.
However a non-lethal DNA test developed by the CSIRO enables researchers to determine fish age for three iconic and threatened Australian freshwater species: the Australian lungfish, the Murray cod and the Mary River cod. We outline the technological breakthrough in our research just published.
Our fast, accurate and cost-effective test can be adapted for other fish species. We now hope to share this method to improve the protection of wild fish populations and help promote sustainable fisheries around the world.
Human activity has led to the population declines of the three Australian fish species at the centre of our research.
The threatened Australian lungfish is found in rivers and lakes in southeast Queensland. Its often referred to as a living fossil because its extraordinary evolutionary history stretches back more than 100 million years, before all land animals including dinosaurs.
Man-made barriers in rivers reduce the movement of water, which lowers lungfish breeding rates.
Older lungfish do not have hard otolith structures, which makes determining their age difficult. Bomb radiocarbon, which analyses carbon levels in organic matter, has been used to age Australian lungfish, but this method is too expensive to be widely used.
The threatened Murray cod is Australias largest freshwater fish. The Mary River cod is one of Australias most endangered fish, found in less than 30% of its former range in Queenslands Mary River.
Habitat destruction and overfishing are major threats to Murray cod and Mary River cod populations.
Otoliths can be used to determine age for both these cod species, however this has only been done on a population-wide scale for the more prevalent Murray cod.
Read more: Australia's smallest fish among 22 at risk of extinction within two decades
When cells divide to make new cells, DNA is replicated. This can lead to DNA methylation, which involves the addition or the loss of a methyl group molecule at places along the DNA strand.
Research has found the level of DNA methylation is a reliable predictor of age, particularly in mammals, including humans.
To develop our test, we first worked with zebrafish. This species is useful when studying fish biology because it has a short lifespan and high reproductive rates. We took zebrafish whose ages were known, then removed a tiny clip of their fin. We then examined DNA methylation levels in the fin sample to identify the fishs age.
Following this successful step, we transferred the method to Australian lungfish, Murray cod and Mary River cod. Again, we used fish of known ages, as well as bomb radiocarbon dating of scales and ages determined from otoliths.
We found despite the zebrafish and the study fish species being separated by millions of years of evolution, our method worked in all four species. This suggests the test can be used to predict age in many other fish species.
Read more: Good news from the River Murray: these 2 fish species have bounced back from the Millennium Drought in record numbers
In the same way human population demographers use census data to understand and model human populations, we now have the tools to do this with animals.
We are looking to expand this DNA-based method to determine the age of the endangered eastern freshwater cod and trout cod. We will also continue to test the method across other species including reptiles and crustaceans.
This work is part of CSIROs ongoing efforts to use DNA to measure and monitor the environment. This includes estimating the lifespan of vertebrate species such as long-lived fish and surveying biodiversity in seawater using DNA extracted from the environment.
We envisage that in the not too distant future, these methods may be used by other researchers to better understand and manage wild animal populations.
Read more: A new study shows an animal's lifespan is written in the DNA. For humans, it's 38 years
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Breakthrough allows scientists to determine the age of endangered native fish using DNA - The Conversation AU
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Classic Trail-Themed Colorways Appear On The adidas UltraBOOST 5.0 DNA – Sneaker News
Posted: at 9:50 pm
The term DNA at least in the Ultra Boosts case encompasses much more than the design of the shoe itself. And as it joins the 5.0 iteration, the moniker brings along an array of classic, trail-inspired colorways.
We can expect at least three iterations to surface in the next few days, each vivid as it mimics some of the best outdoors gear. The first, which is arguably the most bold of the trio, renders its knits in a dual-tone of light and dark blue; brighter red fixtures dress the branding adjacent, while the sole features a familiar speckling. Opposite, the Wonder White pair is far more muted as it joins alongside cream threads and a warm and cool color combo. Finally, the last rounds us out with a mix replete with Grey Three, Sonic Ink, and Solar Gold pops.
For a closer look at the range, see the official images below. A release, according to adidas AU, is due for June 30th; expect an adidas.com drop in the US to follow.
In other news, the adidas Trae Young 1 is coming soon.
Where to Buy
Make sure to follow @kicksfinder for live tweets during the release date.
Classic Trail-Themed Colorways Appear On The adidas UltraBOOST 5.0 DNA
Mens: $180Style Code: GV7714
Where to Buy
Make sure to follow @kicksfinder for live tweets during the release date.
Mens: $180Style Code: GV7713
Where to Buy
Make sure to follow @kicksfinder for live tweets during the release date.
Mens: $180Style Code: GV7715
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Classic Trail-Themed Colorways Appear On The adidas UltraBOOST 5.0 DNA - Sneaker News
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