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Category Archives: Transhuman News

Governments Increase Pressure On Twitter To Censor Journalists – Forbes

Posted: July 21, 2021 at 12:31 am

Photo by Leon Neal/Getty Images

Governments are increasingly demanding the removal of journalist content from Twitter, the company's latest Transparency Report shows.

During the second half of 2020, says Twitter, it received 361 legal requests from governments to remove content from the verified accounts of 199 journalists and news outlets, up 26 per cent on the first half of the year.

Overall, the company says it received 38,524 legal demands to remove content specifying 131,933 accounts.

"Although there was a nine per cent decrease in the number of legal demands Twitter received, compared to the previous reporting period, these requests sought removal of content from the largest number of accounts ever in a single reporting period," says Twitter.

Twitter removed some or all of the content concerned in 29 per cent of cases almost all of which came from Japan, India, Russia, Turkey and South Korea.

Meanwhile, India has overtaken the US as the country making the most legal requests for information about accounts, representing a quarter of the total global volume and 15 per cent of the total number of accounts.

India has recently introduced new legislation aimed at regulating social media companies more tightly, and requiring them to appoint India-based chief compliance officers, nodal officers and grievance officers. The government has also stripped Twitter of its safe harbor immunity, meaning it is no longer protected from legal proceedings in the event of unlawful content posted by users.

The US, meanwhile, accounted for 22 per cent of information requests, and more than a third of emergency requests.

Twitter has also introduced a metric for tweets that violate its policies, and says that impressions on these tweets accounted for less than 0.1 per cent of all impressions for all tweets globally.

Of the 3.8 million tweets it removed for violating rules, more than three quarters received fewer than 100 impressions before they were pulled, with only six per cent getting more than 1,000 hits.

Enforcement of rule violation was up in several categories by 142 per cent in the case of abuse and harassment, 194 per cent for non-consensual nudity, 77 per cent for hateful conduct and 175 per cent for civic integrity violations such as the sharing of misleading election information.

Meanwhile, the number of accounts targeted for promoting suicide and self-harm nearly tripled.

There was only a six per cent rise in the number of accounts suspended for violations of Twitter's child sexual exploitation policy, and a 35 per cent fall in suspensions for terrorism and violent extremism.

However, says Twitter, "Varying country-specific Covid-19 restrictions and adjustments within our teams affected the efficiency of our content moderation work and the speed with which we enforced our policies."

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Tucker Carlson: Your private conversations will be controlled by the DNC – Fox News

Posted: at 12:31 am

NEWYou can now listen to Fox News articles!

Last March, as the first big clusters of coronavirus cases started to appear in this country, media executives in Silicon Valley coordinated with officials in Washington to determine how much the public was allowed to know about the growing epidemic that was killing them.

Mark Zuckerberg of Facebook emailed Tony Fauci at NIH, to assure him that Facebook users would see only Tony Faucis approved guidance on COVID-19. Twitter and Google effectively did the same.

Twitter and Google eliminated any post that deviated from Washingtons official line. In many cases, they censored information from front-line physicians that was both medically sound it was the science and potentially lifesaving. Posts about treatments for example were downplayed. They have never apologized for this, they probably never will.

Historians will assess it. They will likely record the early days of COVID-19 as a turning point in our society an unprecedented assault on our most basic civil liberties, that somehow very few people seemed to notice when it first started happening. The usual stooges and think tank libertarians assured us at the time none of it was a big deal. Soulless multinational media monopolies censoring essential medical information? No problem. Thats how the free market works. Build your own Google if you dont like it. Start your own NIH. And anyway, in private you can still say what you want. Youre still free. Its not like this is North Korea. So calm down, conspiracy nut. Youre starting to sound like Alex Jones. Most of us obeyed, we dutifully calmed down, and went back to Netflix.

We shouldnt have. Today we learned the Biden administration considers censorship is applicable to private speech as well. What you say in private, when youre alone with your phone, you wont be able to say or read what you want because the DNC plans to control and apparently have the ability to control the flow the information you receive on your phone. Nothing that questions official regime policy will reach you. According to a report in Politico and believe it or not, we're quoting here directly:

"Biden allied groups, including the Democratic National Committee, are planning to engage fact-checkers more aggressively, and work with SMS carriers to dispel misinformation about vaccines that is sent over social media and text messages."

We'll say that again because its a sentence we never thought wed see written in English: The DNC is planning to censor any quote, "misinformation about vaccines" that you receive privately over text message. What does "misinformation" mean? Its not the same as false information, as factually inaccurate information. Misinformation can be factually true. In fact, it very often is factually true. Thats why theyre angry about it.

Misinformation is anything the Biden administration doesnt want you to know including, for example, how effective the COVID vaccines actually are, and what the potential side effects from them might be from taking them.

Lets say youre interested in finding out that information and looked it up from the administrations own official websites, starting with the VAERS database. Youre no longer allowed to text what you find on their database to other people in this country the country you were born in. Your private conversations will be controlled by the DNC. Is that the picture of a free country?

Looks like we should have worried about civil liberties last year when all this started. "Its a global health emergency. We have no choice. Things will go back to normal when it ends." But will they go back to normal? If the government can ban discussion of the drug theyre making you take, what cant they do? And by the way, are they doing this now, expanding censorship on the conversation about the pandemic as the pandemic recedes? The COVID vaccines have been around for more than seven months. Pretty much everyone who wants a shot has had one. You can get the shot very easily theyre free.

According to the administration, the vaccine works perfectly, so vaccinated people are protected from COVID. Theyre bulletproof. They cant get sick. Thats why they took the vaccine in the first place. So why is official Washington so angry at the people who wont get vaccinated? How precisely do they propose a threat? It makes you think that maybe none of this is really about COVID. Maybe its about social control. Tony Fauci all but admitted that the other day. Heres what he said:

Jake Tapper: I know you have been very clear that the government isn't mandating vaccines, but do you think it's generally a good idea for businesses or schools to require vaccinations? Anthony Fauci: Right. I have been of this opinion, and I remain of that opinion, that I do believe, at the local level, Jake, there should be more mandates.

"There should be more mandates." Actually, they didnt tell us that. Do you remember hearing that when they first rolled out the vaccine, that were for mandates? No, they said theyre not for mandates actually but now they are. These drugs will be mandatory, in many places they already are. If you want to get an education, for example, you need to take one. Many questions arise from this deep questions about civil liberties and what it means to be a free country. But even on a medical level, questions arise for example: Do we know enough to make these drugs mandatory?

Just today, The Washington Post reported that the FDA is preparing to announce a new warning for the Johnson and Johnson coronavirus vaccine, saying it's been linked to a nerve DISORDER called GBS, which can cause paralysis and has. Millions of people in this country alone have taken the Johnson and Johnson shot, but other vaccines could be implicated, too. According to the government's own VAERS database, which tracks vaccine side effects, GBS has been reported as a potential symptom for every other COVID vaccine too. Thats not a small thing. If that sounds familiar, you must be over 40 and have a decent memory.

You may recall that in 1976, the federal government ended its mass vaccination program for influenza after several hundred people came down with GBS. People started asking questions, and very quickly, the Ford administration determined the vaccine wasn't worth the risk. But that's not happening now. People are not asking those questions because they cant theyre not allowed to in public. This is one of the only platforms in all of American media that can operate outside the control of tech monopolies and ask obvious questions. Its not because we're against vaccines we certainly are not but because you have a right to know a lot before you take a medicine. But Tony Fauci isn't stopping the vaccines in the United States. Instead, he's accusing anyone who has questions about the vaccine of having a sinister political motivation. They must be QAnon:

Anthony Fauci: You know, Jake, it's an inexplicable pushing back on the part of some people about getting vaccinated. // I mean, we have got to put aside this ideological difference or differences thinking that somebody is forcing you to do something.//I really don't have a good explanation, Jake, about why this is happening. I mean, it's ideological rigidity, I think. There's no reason not to get vaccinated. Why are we having red states and places in the South that are very highly ideological in one way not wanting to get vaccinations?

So Fauci on the one hand says this should be mandatory and then moments later says for some reason people think we are forcing this on them and thats "inexplicable." They must be right-wingers. You think if you were interviewing them youd say, "Wait a second, didnt you just say it should be mandated? Maybe thats why they think its mandated because you said it was."

But Faucis claim the resistance to the vaccine is somehow political is a bad-faith attack posing as science. In fact, it has been the Democratic Party, very much Anthony Faucis party, that has engaged in partisan discussion about the vaccine from the very first day. Less than a year ago, in September 2020, Kamala Harris announced that the coronavirus vaccine might be dangerous. Why? Because Donald Trump oversaw its development, she said, "is going to be an issue for all of us." Really? No longer an issue because Kamala Harris is in charge. So now that shes in charge anyone asking obvious questions, even nonpartisan questions, must be a White supremacist. Heres Dick Durbin of Illinois doing his best today to divide the country further along partisan lines, because that helps him, and tar anyone who wants more information about a specific drug as a lunatic who is against all vaccines:

Dick Durbin: There are two hosts of programs on Fox Primetime that can only be characterized as anti-vax quacks. Im referring of course to Tucker Carlson and Laura Ingraham. They have been spreading what I consider to be irresponsible information about vaccines across America and about effort of this nation to deal with them.

Spreading irresponsible information. Notice Durbin doesnt accuse us of spreading false information. He did not accuse us of being factually wrong. We havent been. Nor are we against vaccines. Few Americans are against vaccines. Virtually every American has had a ton of vaccines and was expecting to take this one. But when you refuse to answer basic questions about the vaccine and when you dodge them with partisan talking points like that, you make people nervous, Americans have the right to have basic questions answered before taking a medicine, that is their right. But Durbin, and hacks like Fauci, persist in pretending that any resistance to mass vaccination is somehow partisan. That's a lie its a provable lie. Take a look at numbers from the government's own accounting. It turns out that it's African-Americans the Democratic Partys most faithful voters who are still the most hesitant to getting vaccinated. Its not an attack, just an observation.

According to the CDC, from the period of Dec. 14, 2020, to July 12, 2021, a total of 26.2% of African Americans have gotten one dose of a COVID vaccine. Only 23.7% of African Americans are "fully vaccinated."

Those are the lowest number of any racial or ethnic group that the CDC tracks, by a significant margin. We dont judge anybody for taking or refusing to take the vaccine. Medical choices are by definition personal choices. They are not choices that politicians get to make for you. You should never be forced to take medicine you dont want, period. That used to be a common observation. In fact, many people like Dick Durbin, who are attacking anyone who has questions as partisan or racist, are the very same people who told us for decades that they were very upset about the Tuskegee syphilis experiments and they were right to be upset about those experiments, Now theyre telling you that anyone who resists mandatory vaccination is a White supremacist this is the talking point of the moment. You know that because it was on MSNBC from their in-house doctor:

Dr. Chris Pernell: I dont have any tolerance for the anti-vaxxer movement. And I dont have any tolerance for politicians who befriend, who cozy up to, or become allies of that movement. I actually see that as another example of the proliferation of White supremacy. Because in particular, they are targeting communities of color, and they are targeting the historical injustices, the atrocities, that communities of color have experienced, as a way to play on their vulnerabilities.

Imagine someone who would say something so provably untrue, factually untrue, so irresponsible and so divisive having a medical license in this country. That person does. Something is very wrong with our system. Shes claiming African Americans aren't taking the vaccine because White supremacists have asked questions about the vaccine. That's lunacy, of course. A reporter at CNN recently spoke to someone else who offered another explanation for it. It turns out there are people out there maybe because of doctors you just saw who no longer believe the medical experts on cable news anymore:

Amara Walker, CNN correspondent: Do you plan to get vaccinated? Destiny Britt: No time soon. WALKER (voice-over): Twenty-one-year-old Destiny Britt says she's given the COVID-19 vaccine a lot of thought. BRITT: Don't take it as being rebellious. Listen to and understand and be compassionate and sympathize of the history of black people, black and brown people, and the medical industry. WALKER (voice-over): The Atlanta native is skeptical of the vaccines thanks in large part due to the legacy of the unethical Tuskegee study in which Black men with syphilis were deliberately not treated // BRITT: And the more that it's a push for me to go get vaccinated, it makes me not want it even more.

"The more that it's a push for me to go get vaccinated, it makes me not want it even more." And of course, that makes sense. If the vaccine is so great wouldnt it sell itself? There would be no reason to force people to take it.

But people are being forced to take it. The people who are trying to force us are the ones who lectured of for decades about "my body my choice"they are leading the way. The levels of irony here are exhaustible.

The former head of Planned Parenthood, who is a truly irresponsible person called Lena Wen, just went on television to explain how to force millions of Americans to take the drug. It's easy, she said. Just make their lives as miserable as possible until they comply:

CNN Medical Analyst Dr. Lena Wen: It needs to be hard for people to remain unvaccinated. Right now, its kind of the opposite. Its fine. Its easy if youre unvaccinated. You can do anything you want to do anyway. At some point, these mandates by workplaces, by schools, I think it will be important to say, hey, if you want to opt out, but if you have to sign these forms, get twice-weekly testing. Basically, we want to make getting vaccinated the easy choice. That is what its going to take for us to actually end the pandemic.

You wonder the damage this is doing to the credibility of the medical establishment. Most Americans grew up believing in science, believing their doctors, they had every reason to, we led the world in science. Our health care was the best in the world expensive, granted but very effective and the outcomes were remarkable compared to any other place on the planet. That was a system like all systems that worked on trust. You trusted what the medical authorities said. But when they start talking like that, when they start making claims that have no logic, no clear medical justification, theyre just transparently political in that case clearly illegal when they start talking about punishing Americans who dont want to do their will, follow instructions they refuse to explain, policies that will not account for using data, instead they throw talking points at you and bumper stickers and attacking you as immoral whos going to believe them ever again? The damage they are doing to our system is profound. And you think people on the other side would stand up for Americans the Republican Party anyone? Some are, most arent.

And mediocrities like Asa Hutchinson, who pretends to be governor of Arkansas, are in fact joining in and promoting it. Adam Kinzinger, a Republican congressman from Illinois, just demanded that every American take the coronavirus vaccine on national television:

Adam Kinzinger: This is outrage politics thats being played by my party and its going to get Americans killed. Our party has been hijacked, my party has been hijacked. It is on its way to the ground and for some people its a fun ride but this plane is going to crash into the ground. (edit) I call on Leader McCarthy. I call on every leader in the Republican party to stand up, say 'get vaccinated,' and to call out these garbage politicians, these absolute clown politicians playing on your vaccine fears for their own selfish gain.

Adam Kinzinger, in his defense, has a low IQ and cannot be held fully responsible for most of the things he said. But neither he nor anyone else who is making that case has answered a very simple question: why should people whove recovered from COVID-19, and there are millions in this country who are immune to the virus, why should they be forced to get the vaccine? Whats the answer? Whats the harm rate from the vaccine? Why cant we ask? Whats the answer? When you attack people rather than answer their questions they dont trust you anymore and they dont trust the drugs you say they must take and thats a shame. Were not attacking the vaccine, never have. We dont judge anyone who takes it and we never will. We judge people like that.

And where are the Republicans when they learned the Biden administration decided they can police your text messages? That the DNC is in charge of what you text to other Americans? There is almost no resistance to it in Washington. That means it's likely going to get worse.

And for people who are working in the United States military, who must obey, its going to get much worse. It's clear now that the military is going to expel anyone who doesnt get the shot.

The Department of the Army headquarters just announced an executive order to make the vaccine mandatory by Sept. 1. It's the first time since the Army forced soldiers to take a vaccine since the anthrax vaccine a decision that killed and injured several soldiers. One naval officer explained how he's being coerced.

Quote: "I'm a naval officer who's spent the last 15 years on active duty. I'm now potentially facing forcible discharge if I won't submit to taking the COVID vaccine. ... I've spoken to two command chaplains regarding religious exemption (I'm a Christian abortion abolitionist and cells from aborted children were used in the vaccines' development), and am told exemptions won't likely be granted. So, my choices are vaccination and forcible discharge."

There's no scientific basis for this. In the thread, the naval officer lays out the data to prove how unnecessary this is. The numbers are straight from the Department of Defense's website.

Quote: "202,567 active duty service members have had COVID, of whom 26 have died. [That's] better than a 99.987 percent survival rate."

Those are the numbers, no ones disputing them. Not Adam Kinzinger or Dick Durbin. No one disputes the number so whats the answer? There is no answer. The government is purging the military, and spying on its own citizens, because of a virus that isn't killing very many people anymore. And keep in mind: vaccination isnt like voting. They dont trust you to do it yourself at home and mail in the results. Theyre keeping track. How East German is this country becoming? The FBI just announced in a tweet that it's encouraging Americans to snitch on family members who exhibit signs of "extremism." The federal government the Biden administration is encouraging your family to snitch on each other. Does extremism apply to people who have questions about the vaccine? Of course, it does.

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In March, the FBI put out an official bulletin announcing they'd be cracking down on fake vaccine cards. Since then, undercover agents all over the country have been arresting people for distributing unapproved vaccine documents bearing an official government logo. They just conducted a sting operation that nabbed the owner of the Old Corner Saloon in the small town of Clements, California, for example. What's interesting is that the FBI hasn't put out any bulletin on illegal immigrants using fake driver's licenses or Social Security cards lately thats endemic, thats everywhere. They haven't shut down any businesses or harassed any California bar owners for hiring illegal immigrants at a time of mass unemployment. Why havent they done that?

You know the answer. The people running the government have one standard for enforcing the law for people who agree with them, and a different one for those who don't agree with them. That is third world. Now those same people just gave themselves the power to read and censor your text messages. We got to resist this, you cant let this continue. Or else youre going to wake up in a very different place from the place you were born.

This article is adapted from Tucker Carlson's opening commentary on the July 12, 2021, edition of "Tucker Carlson Tonight."

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Social Media Drags WWE for Censoring Charlotte Flair at Money in the Bank – PopCulture.com

Posted: at 12:31 am

Charlotte Flair is back on top as she defeated Rhea Ripley to win WWE's Raw Women's Champion at Money in the Bank on Sunday night. And while some fans were happy Flair won another title, the majority of fans watching on Peacock were upset with what they did with "The Queen." At the start of the match, Flair gave a middle finger to the crowd, which was censored by the streaming service and WWE. This led to an uproar on social media, but the question is why did Flair do it?

Last year, Flair went on Raw Talk and sent a message to her haters. "It's not about who gets under my skin, it's about why they get under my skin, she said, per Sportskeeda. "I see, I hear, and I read what people say about me that I'm entitled that I'm always in the title picture. Here's the thing, I am the only person that shows up to work 365 days a year. I'm never sick, I'm never hurt, I'm the hardest working person in this company. I'm on RAW, I'm on SmackDown, hell, I do media for FOX and I'm not even on FOX and then they sent me to NXT. I do anything and everything they ask because I love this business and I strive for greatness." Here's a look at social media going after WWE and Peacock for censoring Flair.

One fan wrote: "First Peacock tries censoring a middle finger and now they're trying to censor the entire show.

Another fan wrote: "Screen went black at #MITB I thought The Fiend was about to get in the match. But it was just Peacock trying to sensor Charlottes middle finger."

Another fan thought a big return was happening during the match. The person wrote: "I thought someone was making a return. Nope just the network blocking Charlotte's middle finger to the crowd."

One social media user wrote: "Half the WWE universe thought The Undertaker was going to appear. The other half were waiting for Alexa. Nope, just a middle finger."

"Nice editing by peacock by going to black then coming back as Flair had a middle finger up, cant wait to watch all the censored Austin stuff," another fan noted.

One WWE fan said: Its kinda disappointing on Twitter when a 30-second return, crowds and a middle finger are a bigger topic of conversation than any of the matches themselves. You can say this was the greatest ppv but that does say a lot."

"Charlotte lost it at the 'we want Becky' chants. HAHAHHAHAA & they tried to cut the crotch chop & middle finger. Im weak!" a fan wrote.

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Hawley hammers Facebook and Twitter on collusion with Biden administration to censor speech – kttn

Posted: at 12:31 am

Senator Josh Hawley (R-Mo.) sent letters to Facebook CEO Mark Zuckerberg and Twitter CEO Jack Dorsey demanding answers on their collusion with the Biden administration to suppress free speech. Senator Hawley said the revelations raise questions as to whether the platforms are operating as arms of the federal government.

Senator Hawley writes,This casual admission of collusionbetween the state and corporations that have monopolized the flow of information and therefore dictate the terms of service for the public squareis shocking. The First Amendment is sacrosanct, and it is unconscionable that the federal government has evidently enlisted private actors to police speech in ways that they are unable.

Senator Hawley requested the CEOs provide a full account of social media content flagged by the Biden administration, what content they have been asked to remove, and what content has been removed following the requests.

Read the full letter to Facebookhereand the full letter to Twitterhere.

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This Company Raised $100 Million To Bring Gene Therapy To The Masses – Forbes

Posted: at 12:28 am

Kriya Therapeutics cofounder and CEO Shankar Ramaswamy.

Over the past several years, breakthroughs in gene therapy have led to treatments for rare diseases that were deadly just a decade ago. Take Zolgensmain 2019, it was the first gene therapy approved by the FDA to treat spinal muscular atrophy, a rare genetic disease that affects the mobility of infants and children. But gene therapies have historically had two drawbacks: They are only used for rare diseases, and they carry a hefty price tag (treatment with Zolgensma costs $2.1 million).

Kriya Therapeutics is trying to overcome these obstacles by creating gene therapies for the massesand manufacturing them at a lower cost. On Wednesday, the startup announced that it had raised a $100 million Series B funding round to get it closer to this goal. The round was led by investors from Patient Square Capital and also involved investors from QVT, Dexcel Pharma, Foresite Capital, Bluebird Ventures, Transhuman Capital, Narya Capital, Amplo and the Juvenile Diabetes Research Foundation T1D Fund.

We think this is going to be an extraordinarily important therapeutic class that will revolutionize the treatment of many diseases, says Jim Momtazee, managing partner at Patient Square Capital.

The Silicon Valley-based company was founded in late 2019 by three pharmaceutical industry alums, including a former cofounder of Spark Therapeutics and the former president of United Therapeutics Corp. Shankar Ramaswamy, Kriyas CEO, was part of the foundational team at Roivant Sciences. The new round brings the companys total funding to $180 million; the company declined to reveal its valuation.

Kriyas main focus is its uniquely designed Adeno-associated virusesviruses that are harmless when they enter the body, but deliver instructions to cells that then pump out genes that are missing in some people with genetic diseases. Though the company still plans to develop treatments for rare diseases, what sets it apart is its focus on more common genetic diseases, like some forms of diabetes and obesity. So far, gene therapy has been really constrained in many respects from achieving its full potential, Ramaswamy says. We are believers in gene therapy being applied to rare diseases as well as prevalent diseases.

Ramaswamys goal is to build a company that can go from genetic target discovery to manufacturing and then full commercialization of new therapies, unlike a typical biotech startup that might partner with a large pharmaceutical company for the later stages of development (Ramaswamy says the company will be open to partnerships, but can bring a drug to commercialization on its own). Once the company discovers and develops new gene therapies, its 51,000-square-foot manufacturing facility in North Carolina can produce Adeno-associated viruses at scale to deliver the genes to patients in need. Ramaswamy says that capability will bring down the cost, with savings passed along to patients. I think the innovations that were delivering will make gene therapies much more affordable and accessible to patients, he says. We are very committed to not being a burden on the healthcare system.

The companys current pipeline of products are all preclinical, though Ramaswamy says that they plan to submit Investigational New Drug applications to the FDA for several products in late 2022 and early 2023. So far the company is developing gene therapies for type 1 diabetes, solid tumors and two eye conditions: geographic atrophy and uveitis. In the U.S., more than 3 million people combined have at least one of these conditions, meaning Kriya has a huge pool of potential customers. By comparison, there are fewer than 25,000 children and adults with spinal muscular atrophy in the country.

Ramaswamy says that the new capital will go toward continuing the companys explosive growthit now has 80 full-time employeesas well as refining its vector delivery platforms and manufacturing capabilities. In the future, the money will allow the company to continue to develop new gene therapies for diseases both common and rare. Were taking a very new approach, which is to think more broadly, Ramaswamy says.

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Five minutes with Rafe Johnson – 2021 – Articles – Transform magazine

Posted: at 12:28 am

How did you begin working on the development and ideation of a bionic heart?

I was approached by The Science Museum of Minnesota to design and develop experiences for an upcoming exhibition based around transhumanism, the process of humans merging with technology. One of these projects was to create a 3D hologram animation that presents a series of futuristic bionic organs using the peppers ghost concept which presents the hologram. What I found particularly interesting, and challenging was conceptualising a bionic heart through digital design. I was tasked with designing something that was both visually compelling and yet believable, the design concept had to be to be physiologically so that if it was used to design the physical product it could be implanted into someone, connecting the tubing to their arteries.

The goal of this exhibition, which runs parallel with my own goals, is to introduce the public to the world of human enhancement in an exciting and informative way, and what is more engaging than a holographic image of futuristic implants? There is plenty of science fiction that considers bionic bodies, but they tend to paint a dystopian world that makes us fear technological progress rather than welcome it; I believe its essential we paint an exciting picture of the future in which the capabilities of humans are vastly expanded, and I feel this exhibition portrays that perfectly.

What will designing in AR look like ten years away?

Whilst the fundamental process of designing is unlikely to change, the tools we use during the process certainly will. Augmented reality (AR) is one of the most interesting and exciting tools that can be used for this. As computers continue to reduce in size and increase in power we will see AR devices like the Microsoft Hololens reduce in size from bulky headsets to glasses to contact lenses and eventually brain implants. All aspects of the design process from research to prototyping will become faster, more streamlined and more connected, with areas of design most affected being concepting/prototyping and collaboration. We will be able to design, prototype, package and release our creations on one single platform, just as we often do with computers now. Our freedom to design where and when will be improved, despite your location; and our ability to collaborate will greatly increase as you'll be able to sync with collaborators anywhere in the world and instantly feel like you are in the same room as them. Discussing changes to your car design that's represented digitally in front of you, quickly making tweaks to the cars surfacing or perhaps the paint finish. At Seymourpowell we are already utilizing this technology, for example, when we were building the interior of Virgin Galactic's spaceship, I could be in my home in VR taking in feedback from a 3D avatar representation of my colleagues as we analyzed the inside of the ship. This allowed me to test and identify issues far more closely and talk to top designers around the UK.

What role does extended reality (XR) play in the world of transhumanism?

XR will play a very prominent role in the world of transhumanism, perhaps one of the most important roles. It's worth asking what reality is at this point. Reality in its simplest form is the sum or aggregate of all that is real or existent within a system. Our experience of reality is largely defined by our senses. If our sensory organs and brains can be adjusted, then so can our reality. In decades to come we may be able to experience things we cant yet comprehend. Neuroscientist David Eagleman is already exploring sensory substitution, creating a vest that converts audio data to vibrations, allowing users to feel sounds. His findings show that after some time users who have lost their hearing can start to understand what others are saying through these vibrations. As AR becomes more integrated into our lives, the more we will rely on extended reality technologies, just as we rely so heavily on our mobile phones now. Elon Musk argues that our attachment to mobile phones already makes us a form of early cyborg, imagine trying to go about your daily life without using a mobile phone. Whilst some voice understandable concern about having technologies so closely connected to our bodies, there are huge benefits, especially in the medical world. We will develop a much closer understanding and level of control of our own bodies and XR will be our primary way of interfacing with this.

What is the future of neural implants and how is the design process defining this?

A neural implant is a piece of technology implanted into the brain. Currently they're in the very early stages, however, many neuroscientists and tech leaders are working on prototypes and testing. It's likely the first brain implants will be used for medical purposes like repairing eyesight or reversing effects of other neural based diseases. The technology will inevitably move into the world of brain enhancement, for example a brain computer interface (BCI), which does exactly what youd think, connects your brain directly to a computer. Once we step into the world of altering and enhancing our brains, we really begin to consider the reality of turning ourselves into super humans, science fiction no more! Imagine a world in which brain enhanced humans can learn languages overnight or perhaps communicate telepathically. It will eventually become as easy as closing your eyes and plugging into the virtual world. As with all technologies and inventions, neural implants are driven and developed by the design process. It's the designers job to plan and direct the development of these technologies and ensure the best possible outcome. As with any design project, the prototyping phase is critical in testing and understanding which paths to take, and to help avoid any possible detrimental outcomes.

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Kriya Therapeutics Lands $100 Million to Revolutionize Gene Therapy – Grit Daily

Posted: at 12:28 am

Biotech Startup Kriya Therapeutics has raised $100 million in a Series B funding round to boost its efforts to revolutionize gene therapy for severe diseases like diabetes and morbid obesity.

The Durham-based startup, which also has offices in Palo Alto, had already raised $80.5 million last year. This brings the total funding received by the company to over $180.5 million, as the seed investment received from Transhuman capital was not disclosed.

The Series B funding round was led by Patient Square Capital and counted with the participation of new and existing investors such as Transhuman Capital, QVT Financial, Dexcel Pharma, Narya Capital, JDRF T1D Fund, and more.

The proceeds will be used to further develop the startups core technology platforms, as well as expand its therapeutic pipeline and current programs for metabolic disease, ophthalmology, and oncology.

Shankar Ramaswamy, M.D., Co-Founder and Chief Executive Officer of Kriya Therapeutics, referred to the role the startup will play in the increasingly relevant gene therapy field by stating,

In recent years we have seen the promise of gene therapy become a reality for the treatment of a number of devastating diseases.

However, the field has been constrained by critical limitations in manufacturing technology, vector design capabilities, and cost.

Kriya was formed with the mission of revolutionizing how gene therapies are designed, developed and produced by fully integrating advanced manufacturing technologies, computational tools and development capabilities within a single company.

Jim Momtazee, Managing Partner of Patient Square Capital, will join Kriyas Board of Directors, which will provide the startup with over 31 years of experience in the health industry, being part of important institutions. He referred to the startup he will help direct by stating:

We believe that gene therapy will have a transformative impact on medicine over time, and companies that are able to integrate platform capabilities delivering better treatments, lower cost and broader applications of the technology are going to drive that innovation

The biotech startup is part of an industry that has seen a spike in interest from investors as a result of the failures revealed by the Covid19 pandemic and other health crises in recent years.

The team expects the technology they are developing will prove successful to improve disease-fighting efforts around the globe by providing a more effective and cheaper alternative to traditional therapeutic approaches.

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Durham startup’s $100M fundraiser could help lead to revolution in gene therapies – WRAL Tech Wire

Posted: at 12:28 am

RESEARCH TRIANGLE PARK Kriya Therapeuticsis poised to revolutionize gene therapies for highly serious diseases like diabetes and severe obesity after landing a whopping $100 million in capital.

Thats on top of $80.5 million raised last year.

The biotech startup, with headquarters in Durham and Palo Alto, secured the Series B financing from Patient Square Capital.

Existing institutional investors also participated in this round, including QVT, Dexcel Pharma, Foresite Capital, Bluebird Ventures, Transhuman Capital, Narya Capital, Amplo and JDRF T1D Fund. New investors included Woodline Partners LP, CAM Capital, Hongkou, Alumni Ventures and others.

The company said proceeds from the financing would be used to further develop Kriyas core technology platforms, expand its therapeutic pipeline and advance its current programs in metabolic disease, ophthalmology and oncology.

Gene therapy startup in Triangle lands $100 million in new funding

Meanwhile, Jim Momtazee, managing partner of Patient Square Capital, will join Kriyas board of directors.

In recent years, we have seen the promise of gene therapy become a reality for the treatment of a number of devastating diseases, said Shankar Ramaswamy, M.D., Kriya co-founder and chief executive officer.

However, the field has been constrained by critical limitations in manufacturing technology, vector design capabilities and cost. Kriya was formed with the mission of revolutionizing how gene therapies are designed, developed and produced by fully integrating advanced manufacturing technologies, computational tools and development capabilities within a single company.

Founded in 2019, Kriya is the brainchild of Ramaswamy, former chief business officer for Axovant Gene Therapies; Fraser Wright, co-founder of Sparks Therapeutics; and Roger Jeffs, the former United Therapeutics CEO who has deep rootsinNorth Carolina.

At present, the company is developing its SIRVE (System for Intelligent Rational Vector Engineering) platform for de novo vector design, sequence modification and data analysis.

It is also developing STRIPE (System to Realize Improved Production Efficiency), a proprietary high-efficiency manufacturing platform integrating advances in cell line technology and upstream and downstream process to achieve exponential reductions in production costs at scale.

STRIPE is being developed at Kriyas 51,000-square-foot manufacturing facility in Research Triangle Park.

The companys full cGMP manufacturing infrastructure is expected to be online this year.

(C) N.C. Biotech Center

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Artificial intelligence: governments see huge business potential, but ignore the downsides – The Conversation UK

Posted: at 12:28 am

Many governments are increasingly approaching artificial intelligence with an almost religious zeal. By 2018 at least 22 countries around the world, and also the EU, had launched grand national strategies for making AI part of their business development, while many more had announced ethical frameworks for how it should be allowed to develop. The EU documents more than 290 AI policy initiatives in individual EU member states between 2016 and 2020.

The latest is Ireland, which has just announced its national AI strategy, AI Here for Good. It aims to become an international leader in using AI to benefit our economy and society, through a people-centred, ethical approach to its development, adoption and use.

This is to be obtained via eight policy commandments, including increasing trust in and understanding of AI by using an AI ambassador - a veritable AI high priest to spread the message around the country. Another aspect is to promote AI adoption by Irish businesses and the government within a special moral and ethical framework. There are several shortcomings in this strategy, which it shares with similar efforts by other countries (leaving aside more obviously bad AI strategies, such as that underlying Chinas surveillance state).

Such strategies uncritically share the hype and hysteria surrounding AI. A typical example would be the chief executive of Googles owner Alphabet, Sundar Pichai, claiming in 2016 that AI is one of the most important things humanity is working on. It is more profound than, I dunno, electricity or fire.

He would say this, as his companys business model critically depends on AI, and on people trusting the technology. Irelands strategy goes precisely along with such hype by repeating the claim that AI could double Irish economic growth by 2035. It doesnt detail whose growth, or how.

The strategy lauds various useful existing AI-based apps which, for instance, improve cycling infrastructure in Dublin, provide Irish language tools, save energy, and comfort dementia suffers but it is hard to see how more of these could double economic growth.

Most notably, AI is central to a few digital platform firms such as Google, Apple, Facebook, Amazon and Alibaba - GAFAA for short. They enjoy winner-takes-most benefits due to the fact that current AI requires large amounts of data. As more people use your platform, the profitability of the data grows exponentially.

This has given a huge first-mover advantage to those companies that got it right, turning them into monopolists and gatekeepers. Digital platform firms disrupt existing businesses by out-competing them every time - a good example being how Google, basically an online search-engine, disrupted the advertisement-driven business model of newspapers, or how Apple is selling more watches than the centuries-old Swiss watch industry.

These platforms also depress the start-up of new firms, for instance by buying up all potential new competitors. This stifles innovation.

And increasingly, entrepreneurs have to compete on these platforms for example, Amazon Marketplace. They can be at the mercy of abuses such as fake product reviews by competitors; rulings on such issues by the gatekeepers that are unpredictable and opaque; and sudden algorithm changes that can affect their business by making them, for example, less visible to potential customers. Then there is the phenomenon of digital subsistence entrepreneurs online sellers who barely earn a living wage.

This radically different (anti-) competition landscape sometimes labelled platform capitalism has caused regulators and antitrust authorities substantial headaches. The EU recently adopted proposals for a Digital Markets Act (DMA) and a Digital Services Act (DSA), which try to rein in the actual and potential abuses on large AI-based digital platforms.

If AI and automation had been a force to reckon with, we would have seen skyrocketing labour-productivity growth and rising unemployment. Instead, we see stagnating productivity growth for example, the UKs is the lowest in 200 years - and some of the lowest unemployment rates in western economies in decades.

Irelands AI strategy ignores the above problems with platform capitalism. The name Google appears only once in the entire document, and Amazon and Facebook not at all. There is no reference to digital platforms, platform capitalism, the DMA, DSA or the EUs many antitrust actions against Google. The omission is like Hamlet without the Prince.

Irelands AI strategy should have specified how and when AI will achieve the economic benefits it mentions and who will reap them. It also should have offered a vision of how to make sure that the nation does not suffer from the GAFAAs or become a mere agent of them.

The strategy also assumes that a lack of trust in AI is due to people not understanding the technology well enough. So voil, teaching people data science and having an AI ambassador, like a modern-day prophet, is the answer. One may expect precisely the opposite outcome: the better people understand AI, the less they will trust it.

This would actually be desirable, of course. In the US, where understanding of AI is fairly advanced, adoption rates of AI are in fact meagre. A recent US Census Bureau survey of more than 800,000 US firms found that only 2.9% were using machine learning as recently as 2018. A 2020 survey by the European Commission also pointed to very low adoption levels.

Many other surveys confirm the low adoption rate of AI. Firms do not adopt it, not because they dont trust it, but because it makes little business sense. It is too expensive, usually with paltry returns, and comes with an exorbitant environmental price tag and all that before you factor in the domination of the incumbents.

Irelands AI - Here for Good, like many similar national strategies, seems to believe in miracles, for instance that various circles can be squared. These include enabling access to large volumes of relevant data for all firms while protecting everyones privacy, and turning the country into a powerhouse for training sizeable deep-learning models and massive data centres while cutting CO emissions. It admits no trade-offs.

The implied message is that Ireland can pluck wonderful fruits from a thicket of thorns, just so long as it trusts in AI and adheres to its particular ethical commandments. Transhumanists, GAFAA, and other winners-takes-all in the digital economy will approve wholeheartedly.

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The critical question you need to ask someone if they express a desire to take their own life – NEWS.com.au

Posted: at 12:28 am

CONTENT WARNING: This story contains details that might be triggering to some readers.

Six words could hold the key to guiding someone out of the irrational, impulsive mental state that puts them at dangerously high risk of taking their own life.

People considering suicide generally lose their ability to rationalise, and see the act as a short sharp solution to their pain, clinical psychologist and clinical neuropsychologist Dr Roy Sugarman told news.com.au.

To help pull them away from such a state, asking one specific question could be critical, particularly if the person has expressed feeling as though nothing they do makes a difference.

Asking someone, what is important to you now? could be crucial to their survival, Dr Sugarman said.

Its saying, whatever is going to make a difference, where you feel that what you do does make a difference, Ill do it with you and Ill help you, he said.

The biggest driver is going to be this avoidance of thinking nothing I do makes a difference so I might as well avoid the pain by creating a very short sharp solution to the pain.

People in the grips of such a dire mental state have got there most likely as a result of a collapse in their values and meaningful aspects of their life, Dr Sugarman said.

So when youre asking the question, its in the here and now, and finding out who or what is critical to them at that moment in time, he said.

What to do after asking the question

After getting an answer, Dr Sugarman recommended staying with the person and beginning the process of helping them problem solve, step by step.

Make it manageable and give them a sense that what they do now makes a difference, he said.

Stay with them and help them plan. Help them solve problems.

If we can get people to not look at the big picture, and instead look at things that make a big difference like smaller micro goals, you start to get some movement and progress.

Dr Sugarman stressed that while posing the question may help, it was more important that a warm relationship was maintained over an extended period of time.

Its like anything else, to avoid a terrible event, youve got to maintain your relationship with a person. Its not about weaving some amazing web of speech. Your best chance of keeping someone alive is a warm relationship, he said.

The thing about suicide is that you cant use a rational speech to help a person who has got there by being irrational. The inspiring speech is not going to address the fact that at this stage, there is cognitive depletion. Theyre not going to respond to rationalisation.

Phone app to prevent suicide

Dr Sugarman is the co-founder of suicide prevention app Be A Looper developed alongside Transhuman Inc CEO Amanda Johnstone.

The app, released in 2017, allows users to rate areas of their mental health daily and share their score with four other people they trust.

Ms Johnstone worked closely with RUOK? in the development of the app, and used the same framework, called ALEC, in digitising is at an efficient and practical support tool.

The concept of Be A Looper was largely an extension of Ms Johnstones previous efforts to support her friends. For years she set alarms on their phones and requested they send her an emoji indicating their mental health every day at 4pm.

Ms Johnstone, who was named CEO magazines 2020 Start-up Executive of the Year, independently supported dozens of people for about 12 years before adapting her idea into an app.

I knew that system worked really well and that people would do it, she told news.com.au.

Were all on our phones so often with Instagram and everything, if theres one swipe each day that will make us more connected, it can save lives.

Countless users have contacted Ms Johnstone sharing instances of how an alert from the app which notifies others if someone records a low rating has saved theirs or a loved ones life.

Dr Sugarman said it was no surprise the app had been so effective in preventing suicide, given it harnessed already familiar concepts of swiping and using the 1-10 rating system.

It works because you establish as a routine the sharing of how you feel, so if you are a person who needs to use it, it gets you into the habit of expressing yourself as a number to four other people, he said.

Its very simple, concrete and non verbal, and you will be able to express how you feel when your logic has escaped you and youre a bundle of hot mess an emotions.

The app can be downloaded for free via the Apple app store.

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