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Category Archives: Transhuman News
US Personalized Cancer Genome Sequencing Market
Posted: September 18, 2012 at 9:10 pm
NEW YORK, Sept. 17, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
US Personalized Cancer Genome Sequencing Market
The US personalized cancer Whole-Genome Sequencing market is primarily classified into targeted genome sequencing and Whole-Genome Sequencing. Our report entitled "US Personalized Cancer Genome Sequencing Market" takes into account the Whole-Genome Sequencing services, i.e. one of the most attractive sectors due to its inherent capability of high revenue generation and efficiency in terms of personalized treatment. The US, which is the frontrunner in the provision of such high-end service, is on the focus by market players because of favorable demographics and rising awareness among the industry participants.
In order to properly analyze the virtues and significance of the US personalized cancer Whole-Genome Sequencing market, our report has effectively studied the current and future status of cancer in the whole country as well as states. In view of the fact that cancer affects some age groups in a significant manner, we have also investigated the age wise statistics of the disease. To get proper insight into the market, an in-depth analysis into the high-income group population is provided so that players can have a clear picture about their potential customer base and market to be tapped.
An in-depth study of the regulatory environment governing the US personalized cancer Whole-Genome Sequencing market has also been provided. It has been found that regulations related to personalized cancer sequencing are primarily governed with the accreditation of the laboratories performing the sequencing services and analysis and also the usage of FDA approved tests for conducting these tests. Further we have also discussed the various constraints faced by the industry players with suitable suggestions for overcoming them.
The report analyzes the competitive landscape in the market through properly analyzing the business, services and activities of the companies. It also provides the competitive benchmarking taking into account the strengths and weaknesses of each player. Overall, the report is a complete source of knowledge and statistics for the clients who want to get an in-depth understanding of the market.
1. Analyst View
2. Research Methodology
3. Cancer Statistics by Demographics
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US Personalized Cancer Genome Sequencing Market
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Yale maps “uncharted” genome regions
Posted: at 9:10 pm
Non-coding regions of the human genome play a larger role in cell function than previously thought, scientists from Yale and other schools have shown.
Scientists from Yale and an international research consortium recently published the discovery of information identifying functional regions of the human genome.
Whereas the human genome, sequenced under the worldwide Human Genome Project in 2003, defines the overall structure of human DNA, the new project, titled Encode (ENCyclopedia Of DNA Elements), investigated how many of the elements of DNA work to control activity within the body. The results of Encode, published in over two dozen scientific journals, annotated the human genome by identifying regions previously considered junk as essential for determining cell function. Knowledge gained by the project will help scientists better understand the role of genes in human development and disease, said Sherman Weissman, professor of genetics at the Yale School of Medicine and a member of the project.
The Yale division of Encode was led by Michael Snyder, former chairman of the Yale Department of Molecular, Cellular and Developmental Biology, and launched worldwide in 2003 with a grant from the National Human Genome Research Institute.
John Rinn GRD 04, an assistant professor of stem cell and regenerative biology at Harvard University who was not part of Encode, said that the Human Genome Project left scientists with enormous quantities of unanalyzed information. The purpose of Encode, he said, was to decode those uncharted territor[ies].
Like Magellan navigating the ocean, [Encode] set out to make maps of the genome, Rinn said.
Every cell contains the entire genome, but only reads certain parts for example, a liver cell reads only the section describing the liver, and disposes of the remainder of the genome, Rinn said.
Encode mapped the presence of certain regions containing noncoding RNA, which organizes and determines the activities of various cells by deciding which section of the genome is read for each cell. Scientists were surprised to discover that noncoding RNA exists in equal quantities as messenger RNA (mRNA) that plays a role in protein building.
Weissman said that the results will facilitate other genetic research.
If you want to study an unknown gene, now you can look at [Encode] and see what kind of proteins bind to the DNA near it, or the control sites of nearby DNA, Weissman said. It saves individual laboratories from doing studies on single genes.
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Research and Markets: Global Psoriasis Drug Pipeline Capsule – 2012 Update
Posted: at 9:10 pm
DUBLIN--(BUSINESS WIRE)--
Research and Markets (http://www.researchandmarkets.com/research/t8mv4n/global_psoriasis) has announced the addition of the "Global Psoriasis Drug Pipeline Capsule - 2012 Update" report to their offering.
Fore Pharma's latest report 'Global Psoriasis Drug Pipeline Capsule - 2012 Update' provides most up-to-date information on key Research and Development activities (R&D) in the global Psoriasis market. It covers active Psoriasis pipeline molecules in various stages of clinical trials, preclinical research, and drug discovery.
This report helps executives track competitors pipeline molecules. The information presented in this report can be used for identifying partners, evaluating opportunities, formulating business development strategies, executing in-licensing and out-licensing deals.
The report provides information on pipeline molecules by company and mechanism of action across the R&D stages. It also provides information on pipeline molecules developed in leading geographies (North America and Europe). Licensing activities are thoroughly captured in this report.
Key Topics Covered:
1. Psoriasis - Disease Overview
2. Psoriasis Pipeline Overview
3. Psoriasis Phase 3 Clinical Trial Pipeline Insights
4. Psoriasis Phase 2 Clinical Trial Pipeline Insights
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New gene offers hope for preventive medicine against fractures
Posted: at 9:10 pm
Public release date: 18-Sep-2012 [ | E-mail | Share ]
Contact: Mattias Lorentzon, University of Gothenburg mattias.lorentzon@medic.gu.se 46-031-342-4929 University of Gothenburg
A big international study has identified a special gene that regulates bone density and bone strength. The gene can be used as a risk marker for fractures and opens up opportunities for preventive medicine against fractures. The study, led by the Sahlgrenska Academy, University of Gothenburg, Sweden, was published in the journal PLoS Genetics.
The international study, which involved more than 50 researchers from Europe, North America and Australia and was led by Associate Professor Mattias Lorentzon and Professor Claes Ohlsson at the Sahlgrenska Academy, University of Gothenburg, is based on extensive genetic analyses of the genetic material of 10,000 patients and experimental studies in mice.
Through the combined studies, researchers have succeeded in identifying a special gene, Wnt16, with a strong link to bone density and so-called cortical bone thickness, which is decisive to bone strength.
The genetic variation studied by the international research network could predict, for example, the risk of a forearm fracture in a large patient group of older women.
"In the experimental study, we could then establish that the gene had a crucial effect on the thickness and density of the femur. In mice without the Wnt16 gene, the strength of the femur was up to 61 per cent lower," according to Mattias Lorentzon at the Institute of Medicine, the Sahlgrenska Academy, University of Gothenburg.
The discovery opens up opportunities to develop new medicines to prevent the most common fractures.
"Low cortical bone mass is a decisive factor in, for example, hip and forearm fractures. Unfortunately, the treatments currently used for brittleness of the bones have very little effect on the cortical bone mass," says Mattias Lorentzon.
"If we can learn to stimulate the signaling routes of the Wnt16 gene, we could strengthen the skeleton in these parts too, thereby preventing the most common and serious fractures. The discovery of Wnt16 and its regulation of cortical bone mass is therefore very important," according to Mattias Lorentzon.
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Dan Morain: Promise of youth vote fails to produce at polling places
Posted: at 9:10 pm
The headline was true enough, though it was politically incorrect by today's standards: "Pretty Teen Coed Is First Vote Caster." The Sacramento Bee detailed how Joanne Durbin, that "pretty blonde college student," and a half-dozen other newly minted young voters might change the face of democracy.
At 19, Durbin stepped into the voting booth and cast her ballot in a local El Dorado County election, apparently becoming the first Californian to exercise her right under the 26th Amendment, which took effect July 1, 1971, and lowered the voting age from 21 to 18. Before hurrying off to class at Sacramento State, Durbin surveyed the polling place and noted that no one lined up behind her.
"I guess they are just lazy, like the adults," Durbin, smart kid that she was, told the reporter.
Forty-one years later, Joanne Durbin Testerman is a nurse and a grandmother living in Arizona, where she helps care for her aging parents. She has missed only one election since, though she had a good excuse: She was giving birth to twins. But the youth vote has never materialized.
A product of the Vietnam War era, the 26th Amendment was in place for the 1972 presidential election. We know how that turned out. George McGovern, the peace candidate who sought to mobilize young people outraged by the Vietnam War and draft, won Massachusetts and the District of Columbia, and nothing else.
People described in the newspaper article are now in their 60s. I found a few of them with help from The Sacramento Bee's researcher, Pete Basofin. They all had become regular voters and drilled into their kids' heads the need to vote.
"Politics governs the air you breathe," said Melanie Connors, 61, who spent a career as a child protective services worker. "You need to stay informed and involved."
"I have my two cents. I might as well put it in there. I fought for it," added Tony Kessler. A Navy veteran living in San Luis Obispo, he has voted every time since, except for a few years when he was living in Japan. "I thought things were going to start changing. But nothing happened."
Indeed, four decades later, the vast majority of young people still don't vote. The Public Policy Institute of California estimates that 19 percent of people 25 or younger are likely voters in this state, compared with 74 percent of voters who are 65 and older.
They can't vote if they aren't registered, and they aren't. UC Davis researcher Mindy Romero, project director of the California Civic Engagement Project, has found that a paltry 49.43 percent of eligible voters between 18 and 24 are registered, compared to 77.5 percent in the general population.
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Dan Morain: Promise of youth vote fails to produce at polling places
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Meet the world's first transhumanist politician
Posted: at 9:10 pm
It's not necessarily a negative thing for us to become less human, says transhumanist politician Giuseppe Vatinno
What is transhumanism? Transhumanism is a philosophical doctrine that aims to continuously improve humanity. It promotes science and technology but with people at its centre. Ultimately, it aims to free humanity from its biological limitations, overcoming natural evolution to make us more than human.
How does transhumanism improve humanity? It does this through the development of technologies that boost health and fight ageing and disease, by replacing lost or defective body parts and by improving the internet, communication technologies and artificial intelligence.
Is there a danger that transhumanism could actually make us less human? Becoming less human is not necessarily a negative thing, because it could mean we are less subject to the whims of nature, such as illness or climate extremes. A beautiful sunset is positive, but the black death that struck Europe in the 14th century was not. We want to retain the positive aspects of nature and reduce the negative ones.
But could we become cyborgs? This is more the realm of science fiction. But we are already taking steps in that direction. Look at Oscar Pistorius, the sprinter with two prosthetic limbs. He is able to beat able-bodied competitors.
Why do you think it is important to have a transhumanist politician? Politics is the motor of society, so to bring the battle forward it is important to have a political dimension. I have opposed Italy's "Law 40" that places limits on assisted procreation and have been pushing for more nanotechnology in energy and environmental technology.
Is transhumanism more allied with left- or right-wing politics? In the UK and the US recently, it has been closer to the left, probably because left-wing themes such as bioethics are important to transhumanists at the moment. But economically, the movement probably leans slightly more to the right. Freedom is very important in transhumanism, leading to a focus on individuals and free enterprise.
Is there a conflict with religion? In my opinion, no. Transhumanism does tend to avoid recourse to an external deity and, in fact, most adherents are materialists. But there are also quite a few Hindu and Buddhist transhumanists, and even some Mormons.
Isn't transhumanism, in fact, a religion of science and technology? Yes, in the sense that it could provide ethical principles. The scientific method implies an absolute honesty in producing data and searching for the truth. It could be a model of correctness. A philosopher might argue that a flower is blue rather than red, but science tells you unambiguously what colour it is.
Giuseppe Vatinno trained as a physicist at the Sapienza University of Rome in Italy. In July, the centrist Alleanza per l'Italia politician became the world's first transhumanist to be elected as a member of a parliament
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These 9 startups belong in a futurist’s guide to health technology (infographic)
Posted: at 9:10 pm
A futurist map of disruptive healthcare technology of the future offers a stunning projection of what will be possible. Whats interesting is that much of it is already beginning to take shape in some form or another.
Developed by trend forecasting studio Envision Technologys futurist Michell Zappa with Patrick Schlafer and Colin Popell of Prokalkeo, and featured in FastCompany, the themes focus on developments in telemedicine, augmentation, diagnostics, regeneration and biogerontology over the next 30 years.
Here are nine startups that embody some of the disruptive healthcare technology included in Zappas awesome innovation orb. Wed also like to get your thoughts on other startup companies you think belong in this guide. Post them in the comment space below and tell us what theyre doing to disrupt healthcare.
Diagnostics
UE Lifesciences is a breast cancer diagnostics startup that uses fingertip sensors to detect tumors. Its Intelligent Breast Exam can distinguish between normal breast tissue and a tumor. Breast cancers are stiffer and less mobile than the surrounding tissue, according to a paper documenting the device. It provides a non-invasive, radiation-free alternative to mammograms.
Regeneration
What could be more futuristic than growing skin from plants? Invasion of the Body Snatchers, anyone? Not quite. Eqalix is working with three Philadelphia institutions to grow synthetic skin from soybean protein. CEO Joseph P. Connell sees applications for diabetic foot ulcers, bed sores, trauma and burns. Connell said the synthetic skin addresses the biggest problem in wound healing closing a large wound surface. Also, by using synthetic grafts, there wont be a need to track down and harvest donor arteries in the patients body or from another person. The technologies were developed by researchers and clinicians from Drexel University, the University of Pennsylvania and The Childrens Hospital of Philadelphia.
Augmentation
Ekso Bionics makes exoskeletons for people who have been paralyzed from spinal cord injuries. Heres how it works: electrical motors move the frames joints, mimicking the actions of muscles. The technology has been licensed to Lockheed Martin for soldiers returning from Iraq and Afghanistan.
Telemedicine
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International Space Station: Formal handover of power – Video
Posted: September 17, 2012 at 12:14 pm
16-09-2012 10:33 Expedition 32 Commander Gennady Padalka ceremonially hands over control of the International Space Station to Expedition 33's Suni Williams. . Report by Sophie Foster. Like us on Facebook at and follow us on Twitter at . Subscribe to ITN News!
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Space Station 'nauts touch down on Kazakh steppe
Posted: at 12:14 pm
Three International Space Station crew have made it safely back home, landing early this morning in Kazakhstan in the Soyuz TMA-04M.
Cosmonauts commander Gennady Padalka, flight engineer Sergei Revin and NASA astronaut and flight engineer Joe Acaba touched down just before 4am BST (8:53 local time), after decoupling from the International Space Station's Poisk module five hours earlier.
The 'nauts spent 123 days aboard the station to finish Expedition 32, which featured multiple spacewalks to prep the Pirs module for its replacement and attach a new power-switching unit.
Flicking that switch proved to be harder than the expedition expected when a bolt kept sticking, forcing the crew to take a second run at it.
Japanese 'naut Akihiko Hoshide and NASA 'naut Sunita Williams took those two walks, before lining up to take control of the station and move into Expedition 33 after the Soyuz left.
Williams takes over as commander, while flight engineers Hoshide and Yuri Malenchenko make up the rest of the crew until 12 November.
The station will get a bit more crowded up when flight engineers Kevin Ford, Oleg Novitskiy and Evgeny Tarelkin launch on 15 October for a rendezvous with the ISS on 17 October.
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International Space Station Astronauts Land Safely in Kazakhstan
Posted: at 12:14 pm
Three members of the Expedition 32 crew undocked from the International Space Station and returned safely to Earth on Sunday, wrapping up a mission lasting more than four months.
Flight Engineer Joe Acaba of NASA, and Commander Gennady Padalka and Flight Engineer Sergei Revin of the Russian Federal Space Agency, undocked their Soyuz TMA-04M spacecraft from the space station at 7:09 p.m. EDT and landed north of Arkalyk, Kazakhstan, at 10:53 p.m. (8:53 a.m., Sept. 17, Kazakhstan time). The trio arrived at the station May 17 and spent 125 days in space, 123 of which were aboard the orbiting laboratory.
After the Soyuz spacecraft separated from the space station, NASA astronaut Sunita Williams took command of Expedition 33. Williams is the second woman to command the station. She and her crewmates, Russian cosmonaut Yuri Malenchenko and Akihiko Hoshide of the Japan Aerospace Exploration Agency, will work aboard the station as a three-person crew until the arrival of three new crew members, including NASA astronaut Kevin Ford, in mid-October.
Acaba, Padalka and Revin orbited Earth 2,000 times and traveled 52,906,428 miles. Padalka now ranks fourth for the most days spent in space -- a total of 711 days during four flights.
To follow Twitter updates from NASA's Expedition 33 astronauts, visit: http://twitter.com/Astro_Suni and https://twitter.com/Aki_Hoshide
For more information about the International Space Station and its crew, visit: http://www.nasa.gov/station
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International Space Station Astronauts Land Safely in Kazakhstan
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