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Category Archives: Transhuman News
Male DNA found for first time in female brains
Posted: September 27, 2012 at 4:14 am
Male DNA has for the first time been found inside the female brain, according to new research led by a Canadian scientist.
No, the finding doesn't explain why women sometimes know what their husbands are thinking.
But it could lead to refining what "the self," biologically speaking at least, really means.
Plus, in an unexpected finding, the researchers found that women with Alzheimer's disease had less male DNA in their brains -- and in lower concentrations in the brain region's most affected by the memory-robbing disease -- than women without Alzheimer's.
Observers said the finding also raises the hypothesis that, if male DNA can infiltrate a woman's brain, it might have some "masculinizing" affect on the female brain.
And, if that's so, "what consequences does this have on how the brain functions -- in other words, thinking and behaviour?" said neuroscientist Dr. Sandra Witelson, a professor in the department of psychiatry and behavioral neurosciences at the Michael G. DeGroote School of Medicine at McMaster University in Hamilton.
Appearing in the latest edition of the journal, PLOS ONE, the study is the first to describe the presence of male "microchimerism" in women's brains.
Microchimerism is the "intermingling" of small numbers of cells or portions of DNA in a person or animal from a genetically different inpidual.
In this case, the male DNA found in women's brains most likely came from cells from a pregnancy with a baby boy.
But women can acquire male DNA without ever having a son. In women without boys, male DNA can come from sharing her mother's womb with a male twin, from a non-irradiated blood transfusion and possibly even from an older sibling.
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The Sensitive Skin Diaries: Acne, Rosacea & Eczema Explained
Posted: at 4:14 am
The Sensitive Skin Diaries: Acne, Rosacea & Eczema Explained
When it comes to sensitive skin disorders, there is three main culprits acne, rosacea and eczema (also known as dermatitis). As any sensitive skin sufferer would know, using new products or products not specifically designed for sensitive skin can result in a costly trip to the dermatologist or worse, a very severe reaction, so it's important to understand the basics about our skin, as well as what causes each skin disorder. Knowledge is power when it comes to finding some relief, so keep reading.
Acne
According to the Australasian College of Dermatologists, acne affects 85 percent of Australians at some time during their life now that's a lot of zits! Put simply, acne is caused by a blockage to the opening of the oil glands in the skin. The oil glands are called sebaceous glands, and they produce an oily sheen called sebum (stay with us), which is responsible for keeping skin healthy. Yes, oil is good! Blockages in the sebaceous glands are common in teens, but also in adults if their hormones are seeking some balance. In short: there is no known cure for acne but it is treatable both orally with antibiotics and topically with creams, lotions and gel including benzoyl peroxide and salicyclic acid.
Rosacea
Rosacea is a very common skin disorder that causes red patches, pimple-like bumps and burst capillaries on the face (think of it as a permanent flushed face). Charming, no? The condition is especially common in fair-skinned people aged in their 30s and 40s. While there is no known cause of rosacea, things like hot drinks, alcohol and spicy foods are known to aggravate it. The condition can be controlled with antibiotics, but the Australasian College of Dermatologists recommends sufferers stay away from the aggressors above, but also saunas, sitting next to open fires, harsh winds and hot baths.
Eczema
Eczema is also known as dermatitis, and is a term used to describe inflammation of the skin. Sufferers fall into two categories acute or chronic. Acute eczema consists of itchy, red, oozing patches of skin, and sometimes blisters; while chronic eczema has longer-lasting affected areas that can be thick, dry and prominently marked. This is the result of constant itching and rubbing in an effort to get some relief. There is at least six types of eczema including Varicose (on the legs) and Seborrhoeic (common on the face and scalp), and the key to treatment and management is getting a thorough diagnosis from a dermatologist.
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The Sensitive Skin Diaries: Acne, Rosacea & Eczema Explained
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Community News: Sept. 28 paper
Posted: at 4:13 am
Walk to be held for psoriasis sufferersWASHINGTON, D.C.On Sept. 30, the National Psoriasis Foundation is hosting its annual Walk to Cure Psoriasis in Washington, D.C.at the Franklin Delano Roosevelt Memorial (1850 W. Basin Dr. SW). The event aims to raise funds for the Foundations research, education and advocacy programs. Registration is at 8 a.m.; the walk is at 9 a.m. Walkers of all ages can choose between 1K and 5K routes.To register or for more information, visit walk.psoriasis.org/wdc-walk, or call (877) 825-WALK (9255).
Taste of Stafford to be held AQUIA The Aquia Evening Lions and 17 local restaurants will host an afternoon of delicious food samplings at Taste of Stafford on Oct. 7 from 2 to 4 p.m. Tickets are on sale now for $15 or $20 at door; call Bea at (540) 659-6124 or Dottie at (540) 659-2885. The event will be held at The Clubhouse Restaurant, 204 Bow Cove, Aquia Harbour in Stafford, and will raise funds for eye exams, eye glasses and hearing exams and aids for children.
National Public Lands Day to be held LORTON On Sept. 29, volunteers around the nation will visit their favorite parks, beaches, wildlife preserves, or forests and chip in to help improve these treasured places. Theyll be taking part in National Public Lands Day, the largest, single-day volunteer event for public lands in the country. Bureau of Land Management employees will participate, with volunteers to repair fences, control vegetation and provide boundary surveying. The event will be held Sept. 29 at 10 a.m. at Mustang Trail Head, 10702 Harley Road, Lorton. Call (202) 912-7715 for information.
RAA to hold plant sale FREDERICKSBURG Rappahannock Adult Activities is now hosting a fall plant sale with pansies and chrysanthemums. The sale started Sept. 24 and runs through Oct. 5 at their750 Kings Highway,Fredericksburg location (approximately 3 miles East of theChathamBridge).Sale hours are Monday through Saturday 10 a.m. to 4 p.m.
Wax center, therapy center open this week FREDERICKSBURG The grand opening of the European Wax Center took place Wednesday. The center is located at1935 Carl D. Silver Pkwy, inFredericksburg. The same day, the Physical Therapy of Central Virginia celebrated its grand opening. The physical therapy center is located at10524 Spotsylvania Ave., Suite 102, inFredericksburg.
September is Action Hunger MonthGAITHERSBURG, Md. September is Hunger Action Month. Its no secret that for many families food has become the greatest household expense, and often, there simply isnt enough food. Local elementary school students considered at risk of hunger, however, have come to depend on the weekend Smart Sacks packed by residents with memory loss at the Wilson Health Care Center at Asbury Methodist Village, a Gaithersburg continuing care retirement community.
Working in partnership with the Manna Food Center in Gaithersburg, the Smart Sack program provides the children with backpacks full of food every Friday to ensure they have food on the weekends when there are no school meals to sustain them. According the USDAs most recent statistics, approximately 15 percent ofUnited States households experienced some food insecurity during 2011.
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Community News: Sept. 28 paper
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Johnson: Paul write-in 'meaningless'
Posted: at 4:13 am
Former New Mexico Gov. Gary Johnson, the Libertarian presidential candidate, said Wednesday that writing in Rep. Ron Pauls name on the November ballot will effectively be meaningless.
But that didnt stop Johnson from using his second Reddit Ask Me Anything, an online Q&A, to champion many of the foreign policy doctrines that have made Paul, the Texas Republican and former presidential nominee, a star among libertarian-minded voters.
As much as I support Ron Paul, I think writing in his name will effectively be meaningless, Johnson wrote.
(Also on POLITICO: Johnson has best haul ever)
He also took a hard line against U.S.-led military interventions and said it would be very problematic if Israel bombed nuclear sites in Iran without American backing.
I think that with out U.S. support, that bombing by Israel becomes very problematic, he wrote, adding elsewhere, I would use the bully pulpit of the presidency to point out that bombing Iran would result in another 100 million enemies to the country, that otherwise would not have existed. STOP MILITARY INTERVENTIONS!
Johnson, a two-term former governor, dropped his bid for the GOP presidential nomination after he was shut out of the nationally televised primary debates earlier this year. He later decided to pursue the Libertarian Partys nomination, which he won in May. He will appear on the November ballots in 47 states, including Washington, D.C., and the party is litigating in Michigan, Oklahoma and Pennsylvania to appear on ballots there.
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Computer glitch delays space station undocking
Posted: September 26, 2012 at 1:12 pm
An unmanned European cargo ship as large as a double-decker bus inside will have to wait a bit longer before leaving the International Space Station due to computer problems, NASA officials say.
The robotic Automated Transfer Vehicle 3 (ATV-3) spacecraft was slated to undock from the space station Tuesday evening, but a technical glitch with a laptop computer inside the station prevented to orbital departure. The two spacecraft were scheduled to part ways at 6:35 p.m. EDT (2235 GMT).
"We're not undocking today, that's been canceled," a flight controller in Mission Control told the station's three-person crew.
Space news from NBCNews.com
Science editor Alan Boyle's blog: A new comet superstar named C/2012 S1 (ISON) is heading for the spotlight starting in November 2013 but will it perform as some hope it will, or will it be a dud of cosmic proportions?
The computer glitch apparently interrupted signals from a laptop computer inside the station that serves as a command panel for the departing ATV-3 spacecraft. The computer is inside the Russian-built Zvezda module, the rear-most module that serves as the docking port for ATV spacecraft and visiting Russian spacecraft. [ Photos: Europe's Robotic ATV Spaceships ]
Station commander Sunita Williams of NASA told Mission Control that commands sent from the laptop apparently were not reaching the ATV spacecraft. Engineers are expected to meet early Wednesday to discuss the malfunction and determine when the next undocking attempt can be made, NASA officials said.
The space station's current Expedition 34 crew includes Williams, Japanese astronaut Akihiko Hoshide and Russian cosmonaut Yuri Malenchenko.
The ATV-3 spacecraft, which is also known as Edoardo Almadi in honor of the late Italian physicist of the same name, is the third unmanned cargo ship built by the European Space Agency to send food, water, science gear and other supplies to the International Space Station. The spacecraft launched to the station in late March and delivered 7.2 tons of food to the orbiting lab.
The cylindrical ATV spacecraft are 32 feet long (10 meters) and nearly 15 feet wide (4.5 m). They are disposable spacecraft designed to fly themselves to the space station, and then be jettisoned at mission's end to burn up in Earth's atmosphere somewhere over the Pacific Ocean. The European Space Agency commands the spacecraft from a mission control center in Toulouse, France.
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Computer glitch delays space station undocking
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FBI makes headway on DNA testing backlog, report says
Posted: at 1:12 pm
By Carol Cratty, CNN Senior Producer
updated 5:24 PM EDT, Tue September 25, 2012
STORY HIGHLIGHTS
Washington (CNN) -- The FBI lab has made strides in cutting down its backlog of forensic DNA cases, according to a report released Tuesday by the Justice Department's Office of Inspector General.
As of March 2012 the backlog stood at 403 cases compared to 3,211 cases two years prior.
The report attributed the improvement to increased use of automation, more staff and a focus on using DNA analysis in situations in which it's most likely to yield useful results.
The FBI lab tests biological evidence found at crime scenes and items like envelopes, drinking glasses and articles of clothing. The lab does the work for not just the FBI but also for local police departments that don't have forensic labs.
The report found the biggest reduction in cases came in the area of nuclear DNA, in which biological fluids like blood and semen are analyzed. There was not as large a drop in the backlog of cases involving mitochondrial DNA, which looks at such things as teeth, hair and highly degraded fragments of bones.
According to the inspector general, the FBI decided not to examine samples in 300 of the backlogged mitochondrial DNA cases that came from the FBI's Terrorist Explosive Device Analytical Center. The report said it had been policy to submit all hairs found on improvised explosive devices. "The FBI told us that there have been no documented instances for which probative results were generated from these mitochondrial DNA examinations," said the report. The FBI changed its policy on analyzing samples from all such cases.
The inspector general said a previous report found the FBI lab doesn't have a system to electronically manage lab information and that was still the case as of June. The report said the FBI spent at least $14 million since 2003 on two failed attempts to come up with such a system. The inspector general said the FBI is trying to develop a new system.
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DNA recovered during Rayney probe
Posted: at 1:12 pm
Up to two male DNA profiles were recovered during the investigation into Corryn Rayney's murder that could not be matched to people in a national database, the trial of her estranged husband Lloyd Rayney has heard.
Forensic scientist Laurance Webb told the WA Supreme Court trial on Wednesday that the DNA profiles, one of which was only partial, were found but could not be matched.
Mr Webb said the DNA profile was weak and there was only a 'low level' indication of a second person.
The court heard Rayney, a prominent Perth barrister, could not be 'included or excluded' as a potential source of the DNA found on a handkerchief at Ms Rayney's grave site.
Under cross-examination, Mr Webb agreed that DNA results from a street directory inside Ms Rayney's car indicated at least three people, although it was unclear if Rayney was one of them.
He also agreed that DNA recovered from the CD button in Ms Rayney's car and from her debit card indicated a male who was not Rayney.
Mr Webb also gave evidence about a cigarette butt found outside the Rayney's home, which the court previously heard was DNA matched to a person 'well known to police'.
A full DNA profile was recovered from the butt, indicating that it had not been there for a long time, Mr Webb said.
The cigarette butt was among items found on a footpath during a police search on August 22, 2007.
The prosecution alleges Rayney murdered his estranged wife at their home in August 7, 2007 and then dragged her across the front yard to her car before burying her body head-first in a bush grave at Kings Park.
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DNA recovered during Rayney probe
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DNA in 1980 Maine murder case shown to match defendant
Posted: September 25, 2012 at 11:14 pm
Posted: September 24 Updated: Today at 12:44 AM Samples from the body of Rita St. Peter match the DNA profile of Jay Mercier, an expert says.
By DOUG HARLOW/Morning Sentinel
SKOWHEGAN DNA samples taken from the body of Rita St. Peter in 1980 match the DNA profile of Jay Mercier of Industry, the man who is charged with sexually assaulting and killing her, a state witness said in court Monday.
click image to enlarge
Murder defendant Jay Mercier looks around the courtroom on Thursday, Sept. 20, 2012 during his trial in Somerset County Superior Court for the death of Rita St. Peter 32 years ago..
click image to enlarge
Rita St. Peter in an undated file photo. She was 20 at the time of her death when her body was found off the Campground Road in Anson on July 5, 1980.
"Unless you have an identical twin, there is no one else in the world with your DNA," Kathy MacMillan, a forensic DNA analyst with the state police crime lab, told the jury in Somerset County Superior Court.
MacMillan said the possibility that DNA samples taken from St. Peter's body didn't come from Mercier is one in a trillion.
MacMillan's testimony came on the third day of the murder trial for Mercier, who was 25 when St. Peter's body was found off Campground Road in Anson on July 5, 1980.
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DNA in 1980 Maine murder case shown to match defendant
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DNA Microarray 2012: A Focus on Sales Growth
Posted: at 11:13 pm
NEW YORK, Sept. 25, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
DNA Microarray 2012: A Focus on Sales Growth
Background
From the early use of miniaturised microarrays for the analysis of gene expression in the mid 1990s, this technique has established markets that are expected to reach $3 billion by 2015. However markets are also changing as new applications are developed and new instruments and competitive technologies such as PCR, are launched. Today, more than ever, developers and vendors in the microarray field are targeting their resources in those areas that best support their own sales and growth strategies.
Purpose
This report, based on an analysis of prevailing and emerging market conditions in the DNA microarray field, has been produced to assist marketing and sales, and the identification of new opportunities. It is the outcome of an extensive global study involving more than 200 experienced DNA microarray users. It's findings provide a "focus on sales growth" to developers and vendors in the microarray field, and the changes that are driving these developments.
Analysis
As part of this report, market areas outlined below have been analysed to provide information relevant to marketing and sales, new market opportunities, qualified sales leads, customer needs and future plans, competitive position, new and emerging applications, growing and declining areas and threats.
Market Areas
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By Simply Sharing, Doctors Could Unlock the Genome's Potential
Posted: at 11:13 pm
Software that enables collaboration between labs could make it easier for doctors to translate genome information.
DNA sequencing is increasingly being used in medicine, but doctors can have trouble making sense of the data. Now sequencing machine manufacturer Illumina has announced that it will integrate software into its desktop sequencing platform to assist physicians with that task. The most interesting aspect of the analysis tool may be its ability to share, which could be key to unlocking the real promise of genomics in medicine.
Every person's genome is full of variationsresearch estimates that the genomes of any two people differ at around three million positionsbut most of these differences, called variants, are harmless. But some variants cause disease, and others contribute to the likelihood of disease. When a variant is suspected to affect health, doctors can turn to the scientific literature for clues, but they may not find any useful information there, or they may find data on entire populations that may not apply to an individual patient.
"They want to be able to say, 'We found this variant in an important gene, it may be causing this effect, and we'd love to see if someone has seen this before,' " says Brad Ozenberger of the National Human Genome Research Initiative. But there's currently no centralized collection of medically relevant variants for doctors to use. Some National Institutes of Health-run databases include genetic variants linked to disease and drug response, but they are more suited for researchers than doctors. To address this issue, the National Human Genome Research Initiative announced this summer that it will fund such a centralized database.
"The grand vision is that whenever any patient gets their genome sequenced and analyzed, doctors will be able to tap those data," says Ozenberger.
The commercial answer to the question may come from Illumina's new collaboration with Partners HealthCare, a consortium of hospitals in the Boston area. Partners developed the interpretation software, and has already used it to support its own clinical interpretation of some 24,000 disease cases, says Heidi Rehm, who directs the hospitals' Laboratory for Molecular Medicine.
The software generates a report that might include information such as how a patient's variant will affect the behavior of the gene where it's located and whether one or two copies are needed to see an effect. If a lab has seen the variant before, the report may describe its impact on health. "This notion of a share and share alike network will be very powerful for interpretation of this data," says Rehm.
In the case of Illumina, some of that initial sharing may happen not with whole genome sequencing, but with disease-focused selective sequencing. Last week, the company began taking orders for its tests for autism, cancer, cardiomyopathy, and a broad range of inherited diseases. By sequencing only targeted genes, clinicians and researchers can increase the speed and reduce the cost of the analysis. Illumina's customers can use the Partners Healthcare software to generate reports from this data, and that could help strengthen the power of the technique.
"If I found a variant that's come through my lab that I've never seen, I can go out on my network and see if any other labs have seen it before and see the evidence they used to classify it," says Tim McDaniel, director of Scientific Research in Translational and Consumer Genomics at Illumina. "The dream here is that every lab would be on the network, so that it's not just, 'Has my lab seen it before?' but 'Has any lab seen it previously?' "
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By Simply Sharing, Doctors Could Unlock the Genome's Potential
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