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Category Archives: Transhuman News

Referee charged in husband's death gives DNA sample

Posted: October 4, 2012 at 11:21 am

Lois Ann Goodman, 70, is charged with beating her husband to death with a coffee cup.

Andrew Burton/Reuters

LOS ANGELES (AP) -- A nationally known professional tennis referee charged with the coffee-cup killing of her husband gave police a DNA sample Wednesday after dropping her opposition to the procedure.

Lois Ann Goodman, 70, who is charged with beating her husband to death with the cup last April, was accompanied by about 25 supporters, including friends and relatives, when she appeared briefly in court for a pretrial hearing.

A judge scheduled Goodman's next hearing for Nov. 8.

In the meantime, defense attorneys say they have a huge amount of evidence and court documents provided by prosecutors to review before a trial is scheduled. They also demanded to see original notes taken at Goodman's home by police officers who initially ruled the case an accidental death. In addition, they are seeking notes and recordings from coroner's investigators and the mortician who examined the body.

Goodman was arrested in August just before she was to referee at match at the U.S. Open.

Her attorneys say her 80-year-old husband was the victim of a freak accident.

Authorities initially believed Alan Goodman fell down stairs at home while she was away but later decided it was homicide. Prosecutors now believe he was struck 10 times on the head and stabbed with the broken cup.

The couple was married nearly 50 years with three grown children.

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Fast genome test could help sick newborns

Posted: at 11:20 am

From the day she was born, the baby girl had seizure after seizure as doctors at Children's Mercy Hospital in Kansas City, Mo., frantically tried to keep her alive. Finally, her family decided to let their baby go, and the medical devices were withdrawn. She was 5 weeks old.

Her doctors suspected a genetic disorder, and as it happened, the hospital had just begun a study of a new technique for quickly analyzing the DNA of newborns, zeroing in on mutations that can cause disease.

This new method, published Wednesday in the magazine Science Translational Medicine, is a proof of concept a demonstration that it is possible to quickly scan a baby's entire DNA and pinpoint a disease-causing mutation in a couple of days instead of the more typical weeks or months.

For the study, researchers at Children's Mercy Hospital mapped the DNA of five children. The study's investigators said the test could be one of the first practical fruits of the revolution in sequencing an individual's entire DNA.

For the baby with seizures, her doctors provided a sample of her blood. The analysis took only 50 hours and provided an answer: The baby had a mortal gene mutation so rare that it had only been reported once before.

If only the test could have been done within days of the baby's birth, said Dr. Joshua Petrikin, one of the baby's doctors.

"There was no treatment, there was not anything that could have changed the outcome," Petrikin said. "But we could have more appropriately counseled the family and bypassed what had to have been intense suffering."

The idea behind the test is to take advantage of what is known about disease symptoms to narrow the search for genetic aberrations. And that, said Dr. Joe Gray, an expert in genome analysis at Oregon Health and Science University, "is a good step in the right direction."

"It's a big genome," said Gray, who was not involved with the study. "How do you know what part of it to search?"

The method is expensive, costing about $13,500. It is not yet covered by insurance.

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Fast genome test could help sick newborns

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The Genome — a Pandora's Box?

Posted: at 11:20 am

In its fourth and last segment of its '$1,000 Genome' series, NPR's health blog, Shots, asks what people can expect to learn from their own genome sequence, and why they might not want to learn everything.

Beau Gunderson, a Silicon Valley startup employee, recently had his exome sequenced and found out that he did not inherit an Alzheimer's gene variants and shares some genes with Olympic sprinters, NPR's Rob Stein reports. But Gunderson still wonders what his genome could tell him about diseases he might get.

Others think that sequencing could open a Pandora's Box. "There are also people walking around out there who carry mutations that create an extraordinarily high probability that they will develop a horrendous, untreatable, unpreventable disease by age 50, 60 years old," says James Evans of the University of North Carolina, Chapel Hill. "That isn't necessarily information that everybody wants."

Furthermore, there could be genetic discrimination for life and disability insurance, and in the future, thugs might plant someone's DNA at a crime scene.

But proponents argue the potential benefits of sequencing "far outweigh" any risks, and that people "just have a right to have their genome," Stein writes.

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Information Nation: Digital Social Experiment to Put a Human Face on Big Data

Posted: at 11:20 am

Imagine seeing life through one eyeball but then being given the ability to view the world through two or even three eyeballs at once. You would be greeted with not just more data about your surroundings but a better perspective of how all of that data fit together.

This is the explanation that photographer Rick Smolan gave to his 10-year-old son when asked the meaning of "big data," according to a story he recounted Tuesday at an event he organized in New York City to announce his latest social experiment: The Human Face of Big Data.

For years researchers and technology companies have talked up the notion that extracting meaning from massive amounts of sensor dataproduced everywhere from the oceans' depths to city streets to satellites circling the planetwill have a profound impact on the quality of our lives. Smolan's projectlaunched through his production company Against All Odds and sponsored primarily by EMC Corp.seeks to highlight big data's potential by culling information directly from mobile gadget users worldwide.

For the next two months The Human Face of Big Data is inviting Google Android and Apple iOS mobile device users to answer 60 questions made available in eight languages. The queries touch on a wide variety of users' beliefs, rituals and hopes. One question, for example, hypothetically asks, "If you could enhance your unborn child's DNA in only one way, would you choose: Immunity, Life Span/Longevity, Intelligence, Appearance or Nothing?" Based on the more than 1.5 million answers received through Tuesday morning, it's already clear that respondents who believe in a supreme being are less likely than other participants to want to alter an unborn child's DNA in any way.

Other questions ask respondents where they feel safest in the world, how they cope with stress, what rituals they perform for good luck and one thing they hope to accomplish before they die.

Data collected thus far has come from Android users. Whereas that mobile app launched on September 26, the iOS version currently is languishing in Apple's app vetting process. Project organizers hope to release it soon.

The free mobile apps also automatically gather usage and location data from participants' mobile devices throughout the survey period, which ends November 20. When enough data is collected, participants will be able to access anonymous information about their "data doppelganger"the age, location, gender, percentage of questions answered and other stats of another participant whose profile most closely matches their own.

Smolan and his team plan to make all project data public, but identifying data will not even be collected. The Human Face of Big Data Web site states that the information gathered through the mobile apps will be used for "noncommercial, educational purposes and is intended to provide a fun look at how each user's answers compare with those of other users around the world." The apps do not solicit users' names, e-mail addresses or other contact information, and users need not create a username or password to participate. "Big data is not Big Brother," Smolan said.

The project launch event in Manhattansimilar events were hosted in London and Singaporefeatured a number of speakers elucidating the potential impact of big data. Juan Enriquez, managing director of Excel Venture Management, posited that a person's presence online via blogs, social networks and photos can be thought of as digital tattoos, and that the availability of this information via search engines grants people a kind of immortality. Aside from any permanence that can be achieved, Esther Dyson, a venture capitalist and former journalist, pointed out that improvements in the collection and analysis of diet, exercise and sleep data can also help people on a more prosaic level by enabling healthier lifestyles.

A key component of big data is its dissemination, something that charity: water, a nonprofit organization, is leveraging in its effort to make clean drinking water available in developing nations. Founder and CEO Scott Harrison pointed out at Tuesday's event that people are more willing to donate to a cause when they think their money will be used to solve a problem, rather than to pay for administrative costs and employee salaries.

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Quicker gene test may help babies – Thu, 04 Oct 2012 PST

Posted: at 11:20 am

October 4, 2012 in Nation/World

Lauran Neergaard Associated Press

WASHINGTON Too often, newborns die of genetic diseases before doctors even know whats to blame. Now scientists have found a way to decode those babies DNA in just days instead of weeks, moving gene-mapping closer to routine medicalcare.

The idea: Combine faster gene-analyzing machinery with new computer software that, at the push of a few buttons, uses a babys symptoms to zero in on the most suspicious mutations. The hope would be to start treatment earlier, or avoid futile care for lethalillnesses.

Wednesdays study is a tentative first step: Researchers at Childrens Mercy Hospital in Kansas City, Mo., mapped the DNA of just five children, and the study wasnt done in time to help most ofthem.

But the hospital finds the results promising enough that by years end, it plans to begin routine gene-mapping in its neonatal intensive care unit and may offer testing for babies elsewhere, too while further studies continue, said Dr. Stephen Kingsmore, director of the pediatric genome center at ChildrensMercy.

For the first time, we can actually deliver genome information in time to make a difference, predicted Kingsmore, whose team reported the method in the journal Science TranslationalMedicine.

Even if the diagnosis is a lethal disease, the family will at least have an answer. They wont have false hope, headded.

More than 20 percent of infant deaths are due to a birth defect or genetic diseases, the kind caused by a problem with a single gene. While there are thousands of such diseases from Tay-Sachs to the lesser known Pompe disease, standard newborn screening tests detect only a few of them. And once a baby shows symptoms, fast diagnosis becomescrucial.

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Quicker gene test may help babies - Thu, 04 Oct 2012 PST

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Gene diseases in newborns unveiled quicker

Posted: at 11:20 am

WASHINGTON (AP) -- Too often, newborns die of genetic diseases before doctors even know what's to blame. Now scientists have found a way to decode those babies' DNA in just days instead of weeks, moving gene-mapping closer to routine medical care.

The idea: Combine faster gene-analyzing machinery with new computer software that, at the push of a few buttons, uses a baby's symptoms to zero in on the most suspicious mutations. The hope would be to start treatment earlier, or avoid futile care for lethal illnesses.

Wednesday's study is a tentative first step: Researchers at Children's Mercy Hospital in Kansas City, Mo., mapped the DNA of just five children, and the study wasn't done in time to help most of them.

But the hospital finds the results promising enough that by year's end, it plans to begin routine gene-mapping in its neonatal intensive care unit -- and may offer testing for babies elsewhere, too -- while further studies continue, said Dr. Stephen Kingsmore, director of the pediatric genome center at Children's Mercy.

"For the first time, we can actually deliver genome information in time to make a difference," predicted Kingsmore, whose team reported the method in the journal Science Translational Medicine.

Even if the diagnosis is a lethal disease, "the family will at least have an answer. They won't have false hope," he added.

More than 20 percent of infant deaths are due to a birth defect or genetic diseases, the kind caused by a problem

Sequencing whole genomes -- all of a person's DNA -- can help when it's not clear what gene to suspect. But so far it has been used mainly for research, in part because it takes four to six weeks to complete and is very expensive.

On Wednesday, researchers reported that the new process for whole-genome sequencing can take just 50 hours -- half that time to perform the decoding from a drop of the baby's blood, and the rest to analyze which of the DNA variations uncovered can explain the child's condition.

That's an estimate: The study counted only the time the blood was being decoded or analyzed, not the days needed to ship the blood to Essex, England, home of a speedy new DNA decoding machine made by Illumina, Inc. -- or to ship back the results for Children's Mercy's computer program to analyze. Kingsmore said the hospital is awaiting arrival of its own decoder, when 50 hours should become the true start-to-finish time.

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Media watchdog accuses Iran of intimidating journalists

Posted: at 11:19 am

LONDON (Reuters) - A leading media watchdog has accused Iran of trying to cow journalists into silence and self-censorship, adding to international pressure on Tehran over its treatment of activists and the press.

The New York-based Committee to Protect Journalists (CPJ)said Tehran, which is facing tough international economic sanctions over its nuclear program, was also trying to restrict internet access.

"The situation for independent journalists is Iran is worsening by the day," CPJ Deputy Director Rob Mahoney said in a statement on Wednesday.

"High-profile persecutions and imprisonments are an attempt by the authorities to intimidate the media into silence and self-censorship. The international community must speak out against such actions."

The United Nations human rights office called on Tuesday for the immediate release of prominent activists and journalists arrested or intimidated in what it called an apparent clampdown on critical voices ahead of next year's presidential election.

The CPJ expressed concern about Ali Akbar Javanfekr, press adviser to President Mahmoud Ahmadinejad and head of the state-run IRNA news agency, who was jailed for six months for insulting the Supreme Leader and Reuters Bureau Chief Parisa Hafezi on trial on charges of spreading lies and propaganda.

In citing a series of arrests of print journalists, it said Iranian authorities had maintained a 'revolving-door' policy, freeing some temporarily as they took others into custody.

In March, the Iranian government suspended the press accreditation of all Reuters staff in Tehran after publication of a video script on women's martial arts training that erroneously referred to the athletes as "assassins". Since then, Reuters has been unable to report from Iran.

Reuters, the news arm of Thomson Reuters, the global news and information group, corrected the script after the martial arts club complained and apologized for the error.

Reuters' Bureau Chief in Iran, Iranian national Parisa Hafezi, was subsequently charged on several counts including spreading lies and propaganda against the establishment. Hafezi had not been involved in drafting the video script.

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Kent Free Library brings attention to censorship with participation in Banned Books Week

Posted: at 11:19 am

KENT: The Kent Free Library is celebrating Banned Books Week, which runs from Sept. 30 through Saturday. Banned Books Week is an annual national event sponsored by the American Library Association with the dual purpose of promoting reading and generating attention to the issues surrounding censorship.

"We've been participating for over 5 years now, each year we try to create an interesting display of challenged and banned titles," said Melissa Ziminsky, Adult Services Manager at the library.

The ALA's Office for Intellectual Freedom receives reports from communities around the country where certain books are being challenged or are in danger of being banned and compiles lists, including "Banned/Challenged Classics," "Frequently Challenged Books of the 21st Century," "100 Most Frequently Challenged Books by Decade" and "Most Frequently Challenged Authors pages of the 21st Century."

The ALA's official position is condemning censorship and advocating for free access to information.

According to the association's website, for every book that is reported as challenged by libraries, schools or community groups nationwide, an estimated four books that are challenged go unreported. The ALA's compiles its lists using two sources: newspapers and reports submitted by individuals.

Decisions on banned books are specific to the organization or entity banning them, such as a school district or local library. When a book is banned, it is then unavailable in the library that banned it or not taught in the school district that made the decision.

To generate awareness for the cause of freedom of information, the ALA hosts Banned Books Week each fall, typically during the last week of September. As part of the event, the association encourages book retailers, librarians, publishers, teachers and readers to get involved in the effort to advocate for freedom of information.

Also, for the second straight year, the ALA is co-sponsoring the Banned Books Virtual Read-Out, which invites readers to upload videos of themselves reading from their favorite banned or challenged books.

Books are banned for any number of reasons, as illustrated by the ALA's list of the most-banned books for 2011. The No. 1 book on the list, "ttyl" by author Lauren Myracle, has been banned in some communities for offensive language, religious viewpoints, sexually explicit content and being deemed inappropriate for its target age group.

Sexually explicit content is a common reason for books being banned, as are religious issues and racism. Not all of the books are recent, as the 1960 Harper Lee classic "To Kill a Mockingbird" was tenth on the list. The list is heavy on fiction, but there are non-fiction entries as well.

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Cantor revisits 1937 degeneracy, censorship

Posted: at 11:19 am

With increasingly complicated issues of censorship and freedom of expression reverberating around the globe - from the suppression of artist Ai Weiwei to the protests against "Innocence of Muslims" in the Arab world - a glance back toward "Degenerate Art," the notorious 1937 Munich exhibition presented by the Nazis, seems as on point as ever.

"A War on Modern Art: The 75th Anniversary of the Degenerate Art Exhibition" at Cantor Arts Center at Stanford University may not include any of the exact pieces displayed at the original show, artworks that were attacked as "un-German," immoral and undesirable by Adolf Hitler and Joseph Goebbels. Instead, it presents a small, focused selection of 19 prints, watercolors and books by modernists included in the 1937 exhibition of 650 works, drawing mainly on the Cantor Center's permanent collection.

"It's kind of strange, I think, to quote, unquote commemorate something as horrible as this exhibition," says curator Hilarie Faberman by phone from Stanford. "But on the other hand, there were very much issues of censorship and degeneracy in art, continuing through the '80s and '90s."

The sensation created by the photographs of Robert Mapplethorpe came quickly to mind. "In other words, censorship is very much an issue that's alive in our society."

"A War on Modern Art" includes watercolors by Wassily Kandinsky and Conrad Felixmuller, as well as a 1921 self-portrait by Oskar Kokoschka, two lithographs depicting the poor from Otto Dix's 1924 "Hunger!" portfolio, a linoleum cut of a young woman by Christian Rohlfs and two inward-looking prints by Lovis Corinth. The visually dense "Madhouse," "The Yawners" and "Lovers II" by Max Beckmann are part of the same portfolio of prints, some of which were shown in the 1937 exhibition.

"The ideas the artists are working with here are similar," Faberman says. "I think what offended the Nazis about those were the style of the prints and the way space is condensed. You've got all the mentally ill people in the print, which were considered disgusting and dissolute, like anyone who wasn't a part of this pure Aryan ideal - Jews, Gypsies, homosexuals, the physically challenged. Hitler used the show as a tool to show what they thought was sickness in society and how the culture needed to be purified."

Abstract art was considered the offensive purview of the elite, while some more-realistic artists, such as Dix and George Grosz, were attacked by the Nazis for their leftist leanings and unidealized, ugly imagery.

Working off the idea for "A War on Modern Art" from one of her assistants, Mariko Chang, and looking into the Los Angeles County Museum of Art's noted 1991 restaging of the original exhibition, Faberman never before had a chance to sit down and read about the 1937 show.

"It is astounding to see what was in the original exhibit," she says now. "Almost everything we consider important to understanding modern art was labeled as degenerate."

Through Feb. 24. 11 a.m.-5 p.m. Wednesday-Sunday; until 8 p.m. Thursday. Free. Marie Stauffer Sigall Gallery, Lomita Drive at Museum Way, Stanford. museum.stanford.edu.

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Cantor revisits 1937 degeneracy, censorship

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Ron Paul: Why Governments Hate Gold and Love Fiat Money – Video

Posted: at 11:19 am

03-10-2012 20:11 -Please like, share, subscribe & comment! Facebook Backup YouTube channel: Email updates: 10 Ron Paul is America's leading voice for limited, constitutional government, low taxes, free markets, sound money, and a pro-America foreign policy. To spread the message, visit and promote the following websites: (grassroots website) http (official campaign) (Ron Paul in Congress) (grassroots site) http (discussion forum) (latest Ron Paul videos) Disclaimer This video is not-for-profit clip that is uploaded for the purpose of education, teaching, and research, which falls under fair use according to the Copyright Act of 1976 and tips the balance in favor of fair use; all intellectual content within the video remains property of its respective owners.

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