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Battle for Antarctica. Why scientists believe that the Apocalypse may break out on the white continent – The Times Hub

Posted: February 17, 2022 at 7:37 am

Antarctica has long been a bone of contention, but the real Apocalypse around it will begin in 2048. If not before.

Source: focus.ua

Last June, the Journal of The Royal Society of New Zealand published a paper by scientists from the University of Otago proving that New Zealand's original inhabitants, the Maori, discovered Antarctica at least a thousand years before Europeans arrived there in the early 19th century. For this sensational conclusion, New Zealand researchers have studied Aboriginal oral history, as well as all sorts of documents and reports published by various organizations that do not have common academic or commercial channels. It turns out that the Polynesian leader Hui Te Rangior, together with his team, swam into the waters of the Antarctic back in the 7th century and, perhaps, was the first person to set foot on the White Continent.

The discovery may seem like an ethnographic fun, an additional detail in the museum's exposition. However, it fits better into the well-known formula: History is politics thrown into the past. As the scientists themselves have stated, we are creating a platform on which to have much broader conversations about New Zealand's relationship with Antarctica. Why? Because the battle for Antarctica is something that humanity will have to endure in the not too distant future. And each of several dozen countries must find its own casus belli for this a pretext for war.

The legend of El Dorado around the South Pole has fascinated many Europeans since Sir Francis Drake. On the first day of 1739, the French captain de Lozier looked at the cloudy, foggy and ice-bound coast the one that would later be called Bouvet Island. Then he returned home with a description of majestic icebergs and black-and-white penguins that looked like large ducks, but with fins instead of wings.

Almost three decades later, in August 1769, James Cook on the barge Endeavour left England with a secret order to search for the mysterious Southern Continent and find it before the French navigators. He did not find milk rivers and jelly banks. If the Southern Continent existed, then, as Cook had to state after his round-the-world trip, he lay in harsh regions beyond the 40th parallel. But Cook did not calm down. A little later, he made another expedition. On January 30, 1774, he reached 7110, 300 miles beyond the Antarctic Circle. The ice forced him to turn back.

Antarctica holds more than 80% of the world's fresh water perhaps the most important resource in the era of climate change on Earth, which should be fought for.

The Russians and the British landed in Antarctica with a difference of 3 days. It's not hard to imagine how these differences could be used in future disputes over the rights to Antarctica

Photo: Pexels

The story of the race to the South Pole by Robert Scott and Roald Amundsen has grown into legends so that it almost turned into a legend itself. The Norwegian, having bet on dogs (as on what you can ride and what you can eat), won, having reached his cherished goal on December 14, 1911. The Briton, who decided to go on a pony, lost. Having reached the pole a month later than the rival, he, along with the members of his expedition, died on the way back from hunger, cold and physical exhaustion. In the Norwegian film Amundsen Lord George Curzon at a feast in honor of the outstanding Norwegian polar explorer, which was given at the Royal Geographical Society in London, made a toast to the real heroes of the Amundsen expedition dogs (this is how Amundsen described this episode in his scandalous memoirs & # 171; My life as an explorer & # 187 ;).

This drama is often seen as a mixture of romance and vanity. Although the trigger for it was quite economic reasons. In 1908, Great Britain put forward the first territorial claims, which later, after the death of Scott, were formalized by a corresponding royal decree. The role of the deceased researcher in this was noticeable. It was Scott, shortly before his expedition to the South Pole, who claimed that unheard-of coal reserves are hidden in Antarctica. And he was not wrong.

According to modern estimates, the depths of Antarctica contain 150 billion tons of coal. The US Geological Survey claims that the local oil fields are superior to those stored in pantries Saudi Arabia and reach 7 billion tons. Gas is also more than enough more than 4 trillion cubic meters. Uranium is more than in the Congo. There are deposits of copper ore, nickel, molybdenum, mica, lead, graphite, zinc, diamonds and gold. But perhaps the most important resource in the era of climate change on Earth is fresh water. More than 80% of its global reserves are concentrated here.

These riches are so overwhelming to the imagination that patterns of all sorts of myths are woven around them. Perhaps the most famous, passing through the department of conspiracy theory, is about & # 171; Schwabenland & # 187;, & # 171; the promised land & # 187;, created on the White Continent by order and for the needs of Adolf Hitler. In January 1939, the Fuhrer sent an expedition to Antarctica, which began research in the area of Queen Maud Land. But this modest scientific contribution, conspiracy theorists believe, is not the end of the matter. The Nazis, they believe, equipped a network of under-ice bunkers here and even conducted experiments on the production of aircraft. One of the apocrypha testifies that in October 1944, the Commander-in-Chief of the Navy of the Third Reich, Grand Admiral Karl Doenitz, speaking to the cadets of the naval school in Labe, said: & # 171; The German submarine fleet is proud that far, on the edge of the earth, it built for the Fuhrer and the Fatherland a real earthly paradise, an impregnable fortress. Mysterious Schwabenland within the framework of this theory, reeking of the myth of Valhalla allegedly became a refuge for the Fuhrer. He did not shoot himself, but died safely there in 1971 (according to another version, Hitler cruised between Antarctica, Colombia and Argentina). And yes, of course, the secret services of the two superpowers, the USSR and the USA, knew about it.

Polar Silk Road. Chinese workers drain meltwater as part of the opening of the Comandante Ferraz station in Antarctica

They started talking about such a parallel world after the 1946 American Highjump expedition (High jump) led by Admiral Richard Byrd, which included 13 warships and more than 4 thousand people, of which only a few dozen really were scientists, ended without much triumph. Its purpose was to teach military personnel and test materials for a possible war in Antarctica in extreme cold conditions. It took eight months, but it ended almost twice as fast and with the loss of three people. And when Byrd returned home, word spread that Americans were attacked by some unknown aircraft like flying saucers. They had to retreat, although the moment to make Antarctica theirs was, as they say, right for this.

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There were also statements that the USSR prevented the success of the case. The corresponding statement was made by George Kennan, whom the Los Angeles Times later called the architect of the Cold War. Kennan called for the speedy organization of a rebuff to the exorbitantly growing ambitions of the Soviets, who, after the successful end of the war with Germany and Japan, are in a hurry to use their military and political victories to plant the harmful ideas of communism not only in Eastern Europe and China!.

The curtain of secrecy over Operation High Jump still exists. But the basis of all conflicts around the White Continent is still not high-tech surviving Nazis, and his wealth.

One had to go through several clashes in these harsh places (for example, the Argentines with the British in 1952, after which lawsuits began) to understand that a legal settlement here is an urgent need. In December 1959, the Antarctic Treaty was concluded in Washington, which entered into force in 1961 after it was signed by 12 states; during the International Geophysical Year (IGY) 1957-1958, the following countries operated in Antarctica: France, Japan, New Zealand, Norway, South Africa, Soviet Union, UK and USA. These countries have established 55 Antarctic stations.

According to the latest data, 54 states have acceded to the treaty. 29 of them, including all original signatories, have the right to vote. Ukraine, which has the station Akademik Vernadsky in Antarctica, is one of them.

The Argentines have come up with a recipe for how to prove their right to Antarctica. At the end of 1977, they brought a pregnant woman there, who gave birth to a baby there the first on the continent.

The treaty itself did not deny or support national claims to territorial sovereignty in Antarctica, but it did prohibit all parties from establishing military bases, conducting military maneuvers, testing any weapon (including nuclear), or disposing of radioactive waste in the area. He encouraged freedom of scientific research and the exchange of scientific information and personnel in Antarctica. In 1991, in addition to the treaty, the Madrid Protocol was signed, which entered into force in 1998. The agreement, providing comprehensive protection for the Antarctic environment and dependent and associated ecosystems, banned mineral and oil exploration for 50 years and included rules for protecting the Antarctic environment.

The main Achilles' heel of the protocol is the period after which everything in Antarctica can change. That time will come in 2048. All participating countries are preparing for it and it is unlikely that it will do without a fight. At least diplomatically. Methods in order to claim their rights to some of the Antarctic delicacies after the specified period are chosen differently.

Tourist liner in Antarctica

Photo: Pexels

Belay Lounge not everyone's history is as long as that of the New Zealand Maori. Or at least like Russia and Great Britain. Therefore, sometimes you have to turn on other mechanisms to prove birthright. Perhaps the best recipe was invented in Argentina, precisely when, after the death of Juan Peron, a military dictatorship ruled the country.

At the end of 1977, a citizen of this country, who was seven months pregnant, was taken by plane to the Esperanza Antarctic base, where on January 7 of the following year a baby named Emilio Marcos Palma was born, who immediately became a hero in his homeland. Of course, he was immediately granted Argentine citizenship, and he himself was entered into the Guinness Book of Records as the first person in history born on the continent of Antarctica (although there was already a Norwegian Solveig Jacobsen before him, she was born in 1913 on the island of South Georgia, however this area, which contains the ashes of the polar explorer Sir Ernest Shackleton, is not always included in the Antarctic).

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Emilio has become a trump card for future negotiations on the ownership of that sector of the White Continent, which Buenos Aires continues to claim.

Emilio Marcos was not the last Argentine born in Esperanza, as the very program launched by the then government went beyond this isolated case. During the reign of the junta, a dozen families were brought to the base with the same biblical goal: Be fruitful and multiply. And they didn't disappoint either. Moreover, the experience of Argentina prompted Santiago, an obvious competitor of Buenos Aires in this segment of Antarctica, to take similar actions.

The Chileans organized in 1984, the birth of Juan Pablo Camocho at his Frei Montalva base in the South Shetland Islands of Antarctica. The civilian settlement was later named Villa las Estrellas. Simon Romero, a New York Times reporter who has been there, described in January 2016 such sights as a school, sports facilities, and a cemetery. He noted: Fewer than 200 people live in this outpost, founded in 1984 during the dictatorship of General Augusto Pinochet, when Chile sought to support its territorial claims in Antarctica. Since then, this tiny village has been at the center of one of Antarctica's most remarkable experiments: subjecting entire families to isolation and extreme conditions in an attempt to achieve a semblance of normal life at the bottom of the planet.

Whether the experiment succeeded or not, the context makes us think more about its legal aspects.

Today, states that want to bite off as much of the delicious snow cake as possible, like sprinters, are frozen at a low start. No one perceives 2048 as something infinitely far away. On the contrary, everyone reasonably believes that the battle has already begun. And the winner is the one who will not lag behind the requirements of the times.

In August 2011, the Lowy Institute of International Policy of Australia published a paper entitled Antarctica: Assessing and Protecting Australia's National Interest, urging Canberra to start preparing for the 2048 conversation. After all, Australia is the player with the largest share in Antarctica, claiming 42% of the continent. Its claim to the continental shelf in Antarctica is equal to the size of the entire Arctic Ocean.

It seems inevitable that the issue of mineral resources will be raised again in 2048, the document says. This will likely lead to a resurgence of previous arguments from India and Malaysia that Antarctica should be preserved as the common heritage of mankind and its resources should be shared fairly. It would therefore be prudent for Australia to initiate diplomatic consultations with other claimant states in order to develop a common position in response to expected future pressure to withdraw.

Doaa Abdel-Motaal, an environmental expert, says human migration to Antarctica is something to seriously consider

Such views are not exceptional. Everyone understands that the Antarctic Treaty is nothing more than suspension. He, as BBC journalist Matthew Teller, who visited the White Continent, wrote, has no teeth. Faced with increasing competition for surplus natural resources, and unpredictable intelligence gathering opportunities, all he can do like my penguin is scream and slap his feet in the snow.

The main question is not whether the invasion of Antarctica will occur in 2048, but whether it is possible to find an algorithm that would direct it to a civilized channel. Doaa Abdel-Motaal, an environmental expert who traveled to the Arctic and Antarctic, in her book Battle for the Seventh Continent (2016) argues that factors such as global armament, the rise in climate refugees that the world is about to witness, and an increasingly critical search for energy resources will make Antarctica and Antarctica in general a highly sought-after target. The harsh climate will soon cease to be a safety certificate for this region (it was he, and not the Treaty, she believes, that protected the White Continent from a massive invasion).

Is there any good news? There is. Its name is Svalbard. It is the model that guides the Norwegian Arctic outpost, Abdel-Motaal believes, should be taken as the basis for a legal settlement.

By establishing sovereignty without exclusive ownership of economic resources, this model has created a new approach to territorial governance, she writes. It could solve many of Antarctica's problems, allowing territorial claimants to realize their claims while allowing the rest of the international community to share in the benefits of wealth.

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Abdel-Motaal's formula that politicians need to start actively including Antarctica in the climate refugee equation is a little scary. Especially when you remember that some Norwegian politicians have already tried to start a conversation about housing for refugees in Svalbard, albeit without success. However, Abdel-Motaal believes that migration to Antarctica is something that should be considered in all seriousness.

While this idea may seem inhumane, perhaps even politically incorrect due to unfavorable conditions on the continent, this will change, she writes. The harshness of the Antarctic climate can be overcome in the same way as in Greenland, and even this harshness may not seem so bad compared to the alternatives that refugees have.

Such perspectives give off surrealism. 2048 year. There is no war. There are two streams going towards each other. To Antarctica ships with refugees. From there ships towing icebergs to dry shores.

The idea of such transportation was first discussed about two hundred years ago. But in 1970-1980, two French scientists Paul-Emile Victor and Georges Mougin took it seriously with the approval and support of Saudi Arabia. In 2009 they resumed their work using computer simulations. According to their calculations, an iceberg weighing 7 million tons can be delivered from the shores of Newfoundland to the Canary Islands in 141 days, and it will be able to drink 35 thousand people with healing moisture all year round. It is not clear why no one in Hollywood has yet made a new dystopia with thriller elements on this topic. He could finally become a prophet.

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Battle for Antarctica. Why scientists believe that the Apocalypse may break out on the white continent - The Times Hub

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Use of rape-kit DNA to probe other crimes shocks prosecutors – Bay to Bay News

Posted: at 7:31 am

By OLGA R. RODRIGUEZ and STEFANIE DAZIO

SAN FRANCISCO (AP) The San Francisco district attorney's stunning claim that California crime labs are using DNA from sexual assault survivors to investigate unrelated crimes shocked prosecutors nationwide, and advocates said the practice could affect victims' willingness to come forward.

District Attorney Chesa Boudin said he became aware of the opaque practice last week after prosecutors found a report among hundreds of pages of evidence in the case against a woman recently charged with a felony property crime. The papers referred to a DNA sample collected from the woman during a 2016 rape investigation.

Boudin read from the report Tuesday at a news conference and said he could not share it because of privacy concerns, but his office allowed the San Francisco Chronicle to review the documents. The newspaper said the woman was tied to a burglary in late 2021 during a routine search of a San Francisco Police Department crime lab database. The match came from DNA gathered from the same laboratory listed in a report on the sexual assault, The Chronicle reported.

Boudin said someone at the crime lab told him the practice was a standard procedure, according to Rachel Marshall, Boudin's spokeswoman. Crime lab Director Mark Powell did not immediately respond Wednesday to an email from The Associated Press seeking comment.

San Francisco Police Chief Bill Scott said his department is investigating. If he finds his department is using victims DNA to investigate other crimes, he is committed to ending the practice.

A spokesman declined to comment Wednesday on when the results of the investigation can be expected. He said Scott would likely address the allegations later Wednesday during a Police Commission meeting.

There are strict government regulations surrounding DNA collection and analysis on the state and federal level, yet dozens of local police departments around the U.S. have amassed their own DNA databases to track criminals, AP found in 2017.

Its not clear whether that's what occurred in the San Francisco crime lab, or if its what Boudin was referring to as a common practice.

These databases work in the background with very little regulation and very little light, said Jason Kreag, a law professor at the University of Arizona who has studied forensic DNA issues. It doesnt surprise me, and I wouldnt think this is the only instance where it actually happened.

California law allows local law enforcement crime labs to operate their own forensic databases that are separate from federal and state databases. The law also lets municipal labs perform forensic analysis, including DNA profiling, using those databases without regulation by the state or others.

Kreag said there could be other instances where someones DNA is collected for a specific purpose and then run through a database. For example, homeowners could submit their DNA in a burglary case to exclude them, but later that DNA could be linked to another crime.

Would the district attorney have come out so forcefully in a case like that? Kreag asked. He said he has not heard of such a case involving a sexual assault victims DNA.

Several other law enforcement agencies in California and elsewhere around the U.S. pushed back against Boudins assertion that it was a common practice.

New York Police Department Detective Sophia Mason said the agency does not enter victims DNA profiles into databases or use them in unrelated investigations.

Los Angeles Police Chief Michel Moore said: Certainly the department does not do that.

District attorneys in San Mateo, Santa Clara and Sacramento counties also swatted down the suggestion, as did representatives from San Diego police, the Los Angeles County Sheriffs Department crime lab and others.

In Oakland, law enforcement uses sexual assault victim DNA only "in the context of the case for which the evidence was submitted, not to investigate other cases.

As far as I know, its not a widespread practice, said Ilse Knecht, director of policy and advocacy at the Joyful Heart Foundation, which assists survivors of sexual assault, domestic violence and child abuse.

Knecht and others fear the effect on sexual assault victims, many of whom are already reluctant to report their experiences to law enforcement. Experts say only a third of sexual assaults are reported to authorities.

The possibility however remote that an accuser's DNA could be used against them could throw up additional barriers.

I think anybody can understand how survivors would be fearful of reporting after hearing this story, Knecht said.

Nelson Bunn, executive director of the National District Attorneys Association, said he did not personally know of crime labs using DNA in such a manner. Rape-kit DNA should only be used in sexual assault investigations, he said.

Otherwise, trust would be eroded," he said, citing a detrimental effect on justice for victims of sexual assault.

Boudins news conferences did not occur in a political vacuum. The progressive prosecutor faces a recall election in June and has been publicly feuding with local law enforcement.

The clash between his office and the police department intensified this month after the start of a trial against Terrance Stangel, a former police officer facing battery and assault charges for beating a man with a baton in 2019. Its the first excessive-force case against an on-duty San Francisco police officer to go to trial.

Earlier this month, Scott ended an agreement to cooperate in the district attorney's investigations of police shootings, in-custody deaths and uses of force resulting in serious injury because of concerns over the offices impartiality.

Boudin has denied violating the agreement, and the two have since pledged to renegotiate it with help of the state attorney general and San Franciscos mayor and city attorney.

___

Dazio reported from Los Angeles. Associated Press Writer Michael Balsamo in New York contributed to this report.

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Use of rape-kit DNA to probe other crimes shocks prosecutors - Bay to Bay News

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DNA leads to suspects in attempted vending machine robbery – MLive.com

Posted: at 7:31 am

GRAYLING TOWNSHIP, MI DNA found on a pair of eyeglasses led Michigan State Police to suspects who allegedly attempted to steal money from a vending machine that benefits legally blind people, authorities said.

The attempted theft caused an estimated $5,000-worth of damage to the vending machine. As money had recently been collected, there was about $30 in the machine at the time.

All vending machines at State of Michigan Rest Areas and Welcome Centers are owned by the Bureau of Services for Blind Persons; the proceeds benefit legally blind people in Michigan.

During the early hours of Aug. 3, troopers from the MSP Houghton Lake Post were called to the rest area on I-75 near mile marker 252 in Grayling Township. The complainant reported that two people were attempting to break into a vending machine. The suspects fled before troopers arrived.

Troopers reviewed surveillance footage and observed two people attempting to break into the vending machine for an hour. Each person would take turns as a lookout while the other would continue to attempt to break in.

Around 2:15 a.m., another vehicle entered the rest area and the suspects fled. They left behind several items including bolt cutters and eyeglasses. Troopers collected the items and processed the crime scene. Latent prints were lifted, footwear impressions were photographed and evidence was sent to the MSP Crime Lab for analysis.

The MSP Crime Lab obtained a DNA sample from the eyeglasses. The DNA profile was entered into the Combined DNA Index System (CODIS) and a match was found: 46-year-old Heather Jean Briseno, of Ishpeming. Troopers examined a Michigan Secretary of State image of Briseno and compared it to the person in the surveillance footage; it appeared to be the same person.

A report was turned over to the Crawford County Prosecutors Office and an arrest warrant was authorized. Briseno was arrested on Dec. 11 and lodged at Crawford County Jail.

Police continued to investigate to identify the second suspect. Body cam footage from an interaction with Gaylord City Police on the same night as the attempted theft implicated 43-year-old Abby Lorraine Nardi, of Ishpeming, as the other person involved.

A few hours after the vending machine crime, Gaylord police officers were called to a gas station for two people passed out in a vehicle. Officers found Briseno and Nardi asleep. Nardi was arrested for a separate incident. Briseno was transported to a local hospital for evaluation. Body came footage from the officer showed Nardi wearing the same clothing as the suspect in the surveillance video from the rest area.

A second report was sent to the prosecutors office and an arrest warrant was authorized for Nardi. Nardi was arrested in Marquette County in January and transported to Crawford County Jail.

Nardi was arraigned on Tuesday, Feb. 15, in the 46th District Court in Crawford County for one count of malicious destruction of property over $1,000 but less than $20,000, and one count of breaking and entering a coin-operated device.

Briseno was arraigned on Dec. 13 in the 46th District Court in Crawford County for one count of malicious destruction of property over $1,000 but less than $20,000, and one count of breaking and entering a coin-operated device.

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DNA leads to suspects in attempted vending machine robbery - MLive.com

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Psoriasis Drugs Market is predicted to progress at a CAGR of 6.5% to reach a valuation of US$ 21.48 Bn by 2031 – PR Newswire UK

Posted: February 15, 2022 at 6:21 am

An array of agents exist for the symptomatic treatment of psoriasis. Patients with mild-to-moderate psoriasis typically receive topical treatments that modulate gene transcription, promote keratinocyte differentiation, and inhibit cell proliferation.

A number of innovative and advanced therapies for the treatment and management of psoriasis are under development, many of which have novel targets and mechanisms of action. Psoriasis is linked with a number of medical conditions inclusive of psoriatic arthritis, depression, and cardio metabolic syndrome. The most commonly occurring form of psoriasis is chronic plaque.

Common treatment methods of psoriasis include topical administration of vitamin D analogues, glucocorticoids, and phototherapy. Moderate to severe psoriasis often calls for systemic treatment.

Prevalence of psoriasis has displayed a growing trend over the past decade. Rising awareness initiatives regarding psoriasis disease and its management & treatment options, increasing reimbursement support, and growing research & development with the adoption of biologics and biosimilars are some of the factors responsible for impacting the psoriasis drugs market and aiding sales growth.

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Key Takeaways from Market Study

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"Growing adoption of combination therapy and favourable reimbursement support for psoriasis to drive market growth," says an analyst of Persistence Market Research.

Market Competition

Companies such as Amgen and Sun Pharma have been strongly working toward the development of an extensive clinical pipeline and manufacturing of new product lines for the treatment of psoriasis.

Similarly, other psoriasis drug manufacturers are also trying to maintain and strengthen their portfolios through collaborations with local players or distribution partners. All such recent developments related to companies manufacturing psoriasis drugs have been tracked by the team at Persistence Market Research, which are available in the full report.

Key companies operating in the psoriasis drugs market include Janssen Biotech Inc, Novartis International Ltd., Amgen Inc, Pfizer Inc., Takeda Pharmaceutical Company Ltd. Merck & Co, Inc., Abb Vie Inc., Eli Lilly and Company, Boehringer Ingelheim GmbH, and Sun Pharmaceutical Industries Ltd.

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What Does the Report Cover?

Persistence Market Research offers a unique perspective and actionable insights on the psoriasis drugs market in its latest study, presenting historical demand assessment of 2016 2021 and projections for 2022 2031.

The research study is based on the product (topical, oral, and injectable), drug class (interleukin inhibitors, corticosteroids, anti-inflammatory, and tumor necrosis factor inhibitor), distribution channel (hospital pharmacies, retail pharmacies, and e-Commerce), and indication (guttate psoriasis, inverse psoriasis, pustular psoriasis, erythrodermic psoriasis, and plaque psoriasis), across seven key regions of the world.

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Psoriasis Drugs Market is predicted to progress at a CAGR of 6.5% to reach a valuation of US$ 21.48 Bn by 2031 - PR Newswire UK

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Is It Psoriasis or Ringworm? – Health Essentials from Cleveland Clinic

Posted: at 6:21 am

While there are a number of skin conditions that can cause inflamed, itchy and painful patches, two, in particular, stand out thanks to their similarities: ringworm and psoriasis. With overlapping symptoms, it can be hard to tell which is which.

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But if you know what to look for, there are a few differences, including how each condition is treated. To get a better understanding of both psoriasis and ringworm, and how to tell them apart, we spoke to dermatologist Sean McGregor, DO.

The biggest difference between psoriasis and ringworm, says Dr. McGregor, is the origins of each. Psoriasis is an autoimmune condition, while ringworm is a fungal infection. While a persons autoimmune issues trigger psoriasis, you can acquire the ringworm fungus in a number of different ways, he adds, from soil, other humans or even pets.

Additionally, psoriasis is a chronic condition, meaning it never goes away. Ringworm, conversely, will go away with treatment since its simply an infection.

For treatment purposes, of course, its important to differentiate between the two conditions and know which one you have. No matter which you think you have, though, its always important to contact your healthcare provider so you can get proper treatment.

Ringworm and psoriasis have several overlapping symptoms, which is where confusion can sometimes set in, including:

But there are signs that can help you figure out which condition you may be dealing with.

Dr. McGregor says theres one symptom in particular that can help you figure it out. Ringworm gets its name from a worm-like shape around the edges of the rashes, he says.

One other thing to look for, he advises, is a bit of clearing in the middle of a rash. Ringworm tends to have a little clearing in the center of the rash with more of the inflammation or irritation around that border.

While psoriasis doesnt have symptoms that are as clear cut as those of ringworm, there are a few other ways you might be able to tell that its psoriasis and not something else.

First, if the symptoms are recurring and lack that ring-like feature, it may be psoriasis. Since psoriasis is a chronic condition, it doesnt really go away over a few days with treatment like ringworm will.

Second, about 30% of people with psoriasis develop psoriatic arthritis, a type of arthritis closely associated with psoriasis.

As mentioned, the big difference in treatment is that ringworm can be cured, while the chronic condition of psoriasis is managed. No matter which condition you may have, its best to start by talking to your healthcare provider.

For treating ringworm, Dr. McGregor says, The antifungal cream terbinafine 1% is the best over-the-counter treatment available. Lamisil is the most prominent version of this medicine. If you wind up with ringworm on your scalp, though, your doctor will prescribe you an oral version instead of the topical cream.

There are many home remedies you can try for temporary relief for psoriasis, including:

When it comes to more long-term treatment, though, Dr. McGregor says your doctor will recommend topical steroids or Vitamin D ointment.

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Is It Psoriasis or Ringworm? - Health Essentials from Cleveland Clinic

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Early Response to Biologics Linked With Stable Long-term Efficacy in Psoriasis – AJMC.com Managed Markets Network

Posted: at 6:21 am

More patients with moderate-to-severe psoriasis were found to be early responders to ixekizumab vs ustekinumab; all those who achieved early response were associated with stable skin clearance long-term.

Early response to the biologics ixekizumab and ustekinumab was associated with positive long-term efficacy outcomes in the treatment of moderate-to-severe psoriasis, according to study findings published in the Journal of Drugs in Dermatology.

In the management of patients with psoriasis presenting with more severe disease, researchers noted that defining and predicting high levels of clinical response, as well as identifying which patients are at risk of not having such levels, is key in tailoring treatment plans.

Although baseline Psoriasis Area Severity Index (PASI) and body mass index scores have served as modifiable predictors of response, use of these metrics has not consistently determined response to biologic therapies.

Preliminary data have shown early response to treatment is predictive of subsequent clinical improvement in patients with psoriasis, they said.

During ixekizumab treatment, patients who achieve at least a 40% improvement in PASI score (PASI 40) to at least a 50% improvement in PASI score (PASI 50) at weeks 4 and 6 often reach at least a 75% improvement in PASI score (PASI 75) at week 12 with a 90% predictability.

Seeking to further assess how early response rates to biologic therapy may predict long-term response, researchers conducted a post-hoc analysis of the IXORA-S study that compared the safety and efficacy of the interleukin (IL)-17A inhibitor ixekizumab with the IL-12/23 inhibitor ustekinumab in patients with moderate-to-severe psoriasis.

In the analysis, early treatment response rates to ixekizumab and ustekinumab were evaluated by the percentage of patients treated who achieved PASI 50 at week 2 or 4. Early response rates to these therapies were then examined for stable long-term response, as measured by associations with maintaining complete (PASI 100) or almost complete (PASI 90) skin clearance at 80% of monthly visits during weeks 16-52 of treatment.

Nonresponder imputation was used for missing PASI response status, added the study authors.

In their findings, a numerically greater number of patients given ixekizumab achieved early response vs those treated with ustekinumab; these patients were significantly more likely to achieve a stable PASI 90 response (P < .0001) or PASI 100 response (P < .0001) than the ustekinumab group.

Moreover, all patients treated with either ixekizumab or ustekinumab who were identified as early responders were more likely to achieve a stable response of PASI 90 or 100 (Odds Ratio > 1).

In patients with moderate-to-severe psoriasis treated with ixekizumab or ustekinumab, early response was a significant factor in maintaining stable complete or almost complete skin clearance, concluded the study authors. Therefore, rapid response is a clinically relevant factor to consider when optimizing individual therapeutic strategies.

Reference

Augustin M, Gallo G, See K, et al. Early response is associated with stable long-term response in psoriasis patients receiving ixekizumab or ustekinumab. J Drugs Dermatol. 2022;21(2):122-126. doi: 10.36849/jdd.6063

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Early Response to Biologics Linked With Stable Long-term Efficacy in Psoriasis - AJMC.com Managed Markets Network

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Vibeke Strand, MD, on the Success of Secukinumab for Psoriatic Arthritis – MD Magazine

Posted: at 6:20 am

In an interview with HCPLive, Vibeke Strand, MD, MACR, FACP, Division of Immunology and Rheumatology, Stanford University, discussed her study on the effect of secukinumab in patients with active psoriatic arthritis (PsA).

The Phase 3 data displayed clinical and radiographical efficacy. Patients reported significantly sustained improvements across all dose levels compared with placebo.

This study included patients who were naive to tumor necrosis factor (TNF) inhibitor, as well as patients who were TNF-inadequate or TNF-incomplete responders.

Strand explained that patients who have been heavily treated, who are TNF-incomplete responders, might appear less improved because their scores were lower at baseline compared to patients who were TNF-naive. However, they actually reported very similar amounts of improvement.

"If you account for the fact that they're starting with lower scores because they've had the disease for longer, and they've had more failed treatments, what you can see is that actually, they're able to respond as well as a naive population," Strand said. "It's just that the baseline scores are lower."

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Research Report and Overview on Psoriatic Arthritis Therapeutics Market, 2021-2026 – Get News Alert

Posted: at 6:20 am

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Secukinumab in the treatment of psoriatic arthritis or ankylosing spondyloarthritis with multiple sclerosis: a case series with literature review -…

Posted: at 6:20 am

This article was originally published here

Immunotherapy. 2022 Feb 14. doi: 10.2217/imt-2021-0128. Online ahead of print.

ABSTRACT

Background/aim: Multiple sclerosis (MS) is a demyelinating central nervous system disorder with few cases reported to have concomitant spondyloarthritis (SpA) spectrum disorders such as ankylosing spondylitis and psoriatic arthritis. The aim of this study is to evaluate the effectiveness of secukinumab in the treatment of MS and accompanying ankylosing spondylitis or psoriatic arthritis. Materials & methods: In addition to four cases of their own, the authors conducted a systematic literature search. Demographics, comorbidities, symptoms of MS and SpA, medical treatments and changes in clinical and laboratory findings with treatment were recorded. Results & conclusions: After secukinumab therapy, all patients were found to have treatment response regarding axial involvement, without any progression of MS observed. For both SpA spectrum diseases and MS, secukinumab may be an appropriate choice.

PMID:35152720 | DOI:10.2217/imt-2021-0128

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GP fined S$1500 for negligence after giving medication to patient without pre-prescription tests – TODAY

Posted: at 6:20 am

SINGAPORE A retired general practitioner was fined S$1,500 on Thursday (Feb 10) for his negligence in prescribing medication for a construction worker's psoriasis without running pre-prescription tests on the patient first.

Haridass Ramdass, 77, pleaded guilty to a single charge of endangering Savarimuthu Arul Xaviers personal safety by a negligent act. He was handed the maximum fine.

Savarimuthu died in 2014 aged 28. Haridass was originally charged with causing Savarimuthus death by a rash act, but the charge was later reduced by the prosecution.

The medication that Haridass prescribed, methotrexate, is often used in the treatment of cancer and severe psoriasis a skin disease that causes itchy and scaly patches. Methotrexate can also lead to serious and life-threatening toxic reactions.

Haridass ran Tekka Clinic Surgery on his own in the Little India area at the time, the court heard.

Around Oct 20 in 2014, Savarimuthu developed rashes over his body, face and upper and lower limbs. This prompted him to visit three different doctors to seek treatment.

At Healthway Medical Clinic in Chua Chu Kang, he was prescribed an antiseptic solution, some antihistamines and steroid cream. He went back about two weeks when he noticed his skin rashes had worsened.

He was diagnosed with psoriasis and was prescribed largely the same medication.

He then visited Bless Medical Centre in Boon Lay five days later with skin lesions on his body and limbs, which he said he had been having for months with no improvement.

He was again diagnosed with psoriasis and prescribed medication such as psoriasis oil.

On Nov 24 in 2014, he went to Haridass clinic. The doctor noted that he had extensive reddish and round lesions all over his body, including his scalp.

Savarimuthu said that his skin condition had persisted for 20 days, after which Haridass diagnosed him with psoriasis and administered an injection of Dexamethasone, which is an anti-inflammatory steroid.

Haridass also prescribed 10 tablets of methotrexate, 10 tablets of prednisolone similarly used to treat inflammation and 10 tablets of chlorpheniramine, an antihistamine.

The court heard that Haridass was negligent in failing to arrange for or ensure that Savarimuthu underwent the relevant pre-prescription tests for renal function, liver function and full blood count.

As a result, Haridass failed to discover the patients pre-existing renal impairment and was not conscious of the potentially increased toxic side effects of methotrexate.

Past court documents stated thatSavarimuthu later developed neutropenia and mucositis, leading to a fatal invasive fungal infection.

Neutropenia occurs when a person lacks a certain type of white blood cell, which helps to fight infections.Mucositis happens when a persons mouth or gut becomes sore and inflamed a common side effect of chemotherapy for cancer.

Deputy Public Prosecutors (DPPs) Timotheus Koh and Grace Chua said that methotrexate use in patients with impaired renal function should be undertaken with extreme caution as the impairment will decrease the bodys ability to eliminate the drug.

While the prosecutors noted that deaths have been reported following the use of methotrexate in the treatment of psoriasis, they also agreed with the defence not to make reference on whether Savarimuthu had suffered any adverse effect resulting from its consumption.

'GENUINELY REMORSEFUL'The prosecution sought the maximum fine, noting that the sentence must adequately deter negligence by medical professionals.

Doctors are vested with enormous responsibility and influence by their patients who, in entrusting their health and well-being to them, often accept their professional judgements unquestioningly.

This dynamic is even more pronounced in the case of foreign workers like the patient, who lack the knowledge and language ability to effectively interrogate their doctors recommendations, the prosecution added.

The risk to Savarimuthu was also of significant danger, the DPPs said. Methotrexate toxicity has been reported to cause fatal opportunistic infections, such as by fungi, which can be aggravated in patients with impaired renal function such as Savarimuthu.

In mitigation, Haridass lawyer, Senior Counsel Davinder Singh from Davinder Singh Chambers, said that there was no risk of the doctor committing the offence again as he has retired and not renewed his practising certificate.

Haridass is genuinely remorseful and accepts he was wrong, Mr Singh added in agreeing for a fine of S$1,500 to be imposed.

District Judge Eddy Tham noted that the doctor had been charged only with endangering Savarimuthus personal safety.

I will assume that none of the grave consequences (mentioned in court) had come to pass If any significant harm had resulted to the patient, in fact, I would have had no hesitation in imposing a custodial sentence, he told the court.

Those convicted can be jailed for up to three months or fined up to S$1,500, or punished with both.

CORRECTION: An earlier version of the headline implied that the patient had died because of the medication prescribed to him by the doctor. However, the prosecution and defence had agreed his death was not directly linked to the doctor's prescription. We are sorry for the error.

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Category Archives: Transhuman News

Battle for Antarctica. Why scientists believe that the Apocalypse may break out on the white continent – The Times Hub

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Is It Psoriasis or Ringworm? – Health Essentials from Cleveland Clinic

Early Response to Biologics Linked With Stable Long-term Efficacy in Psoriasis – AJMC.com Managed Markets Network

Vibeke Strand, MD, on the Success of Secukinumab for Psoriatic Arthritis – MD Magazine

Research Report and Overview on Psoriatic Arthritis Therapeutics Market, 2021-2026 – Get News Alert

Secukinumab in the treatment of psoriatic arthritis or ankylosing spondyloarthritis with multiple sclerosis: a case series with literature review -…

GP fined S$1500 for negligence after giving medication to patient without pre-prescription tests – TODAY

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