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Category Archives: Transhuman News

Cosmonauts Take Spacewalk Outside Space Station

Posted: April 20, 2013 at 9:46 pm

The six-hour spacewalk involves upgrading the orbiting lab with new experiments to measure charged particle interactions and the effects of microbes on spacecraft materials

By Megan Gannon and SPACE.com

Russian cosmonauts Roman Romanenko (bottom) and Pavel Vinogradov flout outside the International Space Station on April 19, 2013, during the first spacewalk of their Expedition 35 mission. The two men will spend six hours upgrading the station' Image: NASA TV

Two Russian cosmonauts ventured outside the International Space Station Friday (April 19) to begin a six-hour spacewalk to upgrade the orbiting lab with new experiments.

Clad in their bulky Orlan spacesuits, veteran cosmonauts Pavel Vinogradov and Roman Romanenko began their spacewalk just after 10 a.m. EDT (1400 GMT) to install a space weather experiment to the space station's hull and prepare the outpost for the arrival of a robotic cargo ship later this year. You can watch the spacewalk live on SPACE.com, courtesy of NASA TV.

"It's dark outside," one of the cosmonauts said after they opened the hatch of the Pirs docking module, which doubles as a spacewalk airlock and spacecraft parking spot at the station. [Space Station's Expedition 35 Mission in Photos]

The spacewalk's first task is the installation of a new Russian experiment called Obstanovka, which will measure charged particles interact with a variety of materials kept outside of the space station. Obstanovka could offer scientists new insights about how space weather affects the ionosphere, an active region of the Earth's atmosphere, NASA officials explained in a spacewalk description.

Vinogradov and Romanenko also plan to retrieve a Biorisk canister, an experiment that measures the effects of bacteria and fungus on spacecraft materials, as well as part of a materials exposure experiment called Vinoslivost.

"All this is hard work," Romanenko said of the spacewalk in a NASA interview before launching to the station in December. "Also I'm supposed to collect information from other experiments that were installed outside the station."

Vinogradov and Romanenko are also expected to replace a faulty retro-reflector device needed to guide the upcoming arrival of the European Space Agency's Automated Transfer Vehicle 4 an unmanned cargo ship named "Albert Einstein." That robotic spacecraft will launch toward the space station in Juneand park itself at the orbiting laboratory's Russian-built Zvezda service module.

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Cosmonauts Take Spacewalk Outside Space Station

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During space station fix-up, Russian becomes world's oldest spacewalker

Posted: at 9:46 pm

NASA TV

Russian cosmonauts Roman Romanenko (bottom) and Pavel Vinogradov float outside the International Space Station on Friday during a spacewalk.

By Marcia Dunn, The Associated Press

CAPE CANAVERAL, Fla. A 59-year-old Russian cosmonaut became the world's oldest spacewalker Friday, joining a much younger cosmonaut's son for a little maintenance work outside the International Space Station.

Pavel Vinogradov, a cosmonaut for two decades, claimed the honor as he emerged from the hatch with Roman Romanenko. But he inadvertently added to the booming population of space junk when he lost his grip on an experiment tray that he was retrieving toward the end of the 6-hour spacewalk.

The lost aluminum panel 18 inches by 12 inches (45 by 30 centimeters) and about 6 pounds (3 kilograms) contained metal samples. Scientists wanted to see how the samples had fared after a year out in the vacuum of space.

Otherwise, the spacewalk went well, with the spacewalkers installing new science equipment and replacing a navigation device needed for the June arrival of a European cargo ship.

Collecting the experiment tray was Vinogradov's last task outside.

The tray drifted toward the solar panels of the main Russian space station compartment, called Zvezda, Russian for Star. Flight controllers did not believe it struck anything, and the object was not thought to pose a safety hazard in the hours and days ahead.

"That's unfortunate," someone radioed in Russian.

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Cosmonauts tackle equipment installation outside space station

Posted: at 9:46 pm

By Irene Klotz

CAPE CANAVERAL, Florida (Reuters) - A pair of Russian cosmonauts wrapped up a 6-1/2 hour spacewalk outside the International Space Station on Friday, the first of up to eight outings this year to install experiments and prepare the orbital outpost for a new module, officials said.

Flight engineers Pavel Vinogradov, 59, a veteran of seven spacewalks and Roman Romanenko, 41, a second-generation cosmonaut on his debut spacewalk, floated outside the station's airlock at 10:03 a.m. EDT/1403 GMT as the station soared 262 miles over the southern Pacific Ocean.

The primary purpose of the 6-1/2 hour excursion was to set up an experiment that monitors plasma waves in Earth's ionosphere, the outer layer of the planet's atmosphere that extends to about 370 miles into space.

Instruments on two boxes attached to handrails on the forward portion of the station's Zvezda module will measure low-frequency electromagnetic radiation, which, among other triggers, has been tied to earthquakes.

At the other end of the Zvezda module, Vinogradov and Romanenko replaced a faulty laser retroreflector that is part of an automated docking system used by the European Space Agency's cargo transports. The next ship is due to launch in June.

Before heading back into the station, the cosmonauts retrieved another experiment designed to study how microbes affect spacecraft structures and whether microbes are affected by solar activity.

The day's only glitch occurred just before the men wrapped up their six-hour, 38-minute spacewalk. Vinogradov lost his grip on a science experiment that was slated to be returned to Earth. It floated away in the gravity-free world of space.

The lost aluminum panel, which measured about 18 inches by 12 inches and weighed about 6.5 pounds (3 kg), had been anchored outside the station to test how various metals wear in the harsh space environment.

It floated off in the direction of the Zvezda module's solar arrays, but engineers determined it did not hit or threaten the station, NASA mission commentator Rob Navias said.

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'Hard work': Russian spacewalkers swap experiments on space station

Posted: at 9:46 pm

NASA TV

Russian cosmonauts Roman Romanenko (bottom) and Pavel Vinogradov float outside the International Space Station on Friday during a spacewalk.

By Marcia Dunn, The Associated Press

CAPE CANAVERAL, Fla. A 59-year-old Russian cosmonaut became the world's oldest spacewalker Friday, joining a much younger cosmonaut's son for a little maintenance work outside the International Space Station.

Pavel Vinogradov, a cosmonaut for two decades, claimed the honor as he emerged from the hatch with Roman Romanenko. But he inadvertently added to the booming population of space junk when he lost his grip on an experiment tray that he was retrieving toward the end of the 6-hour spacewalk.

The lost aluminum panel 18 inches by 12 inches (45 by 30 centimeters) and about 6 pounds (3 kilograms) contained metal samples. Scientists wanted to see how the samples had fared after a year out in the vacuum of space.

Otherwise, the spacewalk went well, with the spacewalkers installing new science equipment and replacing a navigation device needed for the June arrival of a European cargo ship.

Collecting the experiment tray was Vinogradov's last task outside.

The tray drifted toward the solar panels of the main Russian space station compartment, called Zvezda, Russian for Star. Flight controllers did not believe it struck anything, and the object was not thought to pose a safety hazard in the hours and days ahead.

"That's unfortunate," someone radioed in Russian.

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'Hard work': Russian spacewalkers swap experiments on space station

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DNA isolation – Micro AX Blood Gravity kit A

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Latest World News – Top US court hears DNA rights case – Video

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Random walks on DNA: Bacterial enzyme has evolved an energy-efficient method to move long distances along DNA

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Apr. 19, 2013 Scientists have revealed how a bacterial enzyme has evolved an energy-efficient method to move long distances along DNA. The findings, published in Science, present further insight into the coupling of chemical and mechanical energy by a class of enzymes called helicases, a widely-distributed group of proteins, which in human cells are implicated in some cancers.

The new helicase mechanism discovered in this study, led by researchers from the University of Bristol and the Technische Universitt Dresden in Germany, may help resolve some of the unexplained roles for helicases in human biology, and in turn help researchers to develop future technological or medical applications.

A commonly held view of DNA helicases is that they move along DNA and "unzip" the double helix to produce single strands of DNA for repair or copying. This process requires mechanical work, so enzyme movement must be coupled to consumption of the chemical fuel ATP. These enzymes are thus often considered as molecular motors.

In the new work, Ralf Seidel and his team at the Technische Universitt Dresden developed a microscope that can stretch single DNA molecules whilst at the same time observe the movement of single fluorescently-labelled helicases. In parallel, the Bristol researchers in the DNA-Protein Interactions Unit used millisecond-resolution fluorescence spectroscopy to reveal dynamic changes in protein conformation and the kinetics of ATP consumption.

The team studied a helicase found in bacteria that moves along viral (bacteriophage) DNA. The work demonstrated that, surprisingly, the enzyme only consumed ATP at the start of the reaction in order to change conformation. Thereafter long-range movement along the DNA was driven by thermal motion; in other words by collisions with the surrounding water molecules. This produces a characteristic one-dimensional "random walk" (see picture), where the protein is just as likely to move backwards as forwards.

Mark Szczelkun, Professor of Biochemistry from the University's School of Biochemistry and one of the senior authors of the study, said: "This enzyme uses the energy from ATP to force a change in protein conformation rather than to unwind DNA. The movement on DNA thereafter doesn't require an energy input from ATP. Although movement is random, it occurs very rapidly and the enzyme can cover long distances on DNA faster than many ATP-driven motors. This can be thought of as a more energy-efficient way to move along DNA and we suggest that this mechanism may be used in other genetic processes, such as DNA repair."

The work in Bristol has been funded by the Wellcome Trust through a programme grant to Professor Mark Szczelkun from the School of Biochemistry.

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DNA study suggests human immunity to disease has ethnicity basis

Posted: at 9:45 pm

BURNABY, British Columbia, April 19 (UPI) -- Immunity to disease may vary depending on ethnicity so designing treatments that will work for everybody may be impossible, U.S. and Canadian researchers say.

DNA sequencing suggests human antibody genes and how well they operate -- and what they can fight off -- can vary from person to person, and ethnicity may influence immunity, a release from Simon Fraser University in British Columbia reported.

The researchers say the finding is based on sequencing the immensely repetitive DNA in the human genome's 1 million nucleotide-long immunoglobulin heavy (IGH)-chain locus -- long known as the most prolific producer of the 50-plus varied and diverse antibody-encoding genes that cells use to fight off infections and diseases.

"Time will confirm the extent to which this is true. But we've found that sections of the IGH-chain locus' DNA sequence are either missing or inserted into a person's genome, and this could vary depending on ethnicity," Corey Watson, a postdoctoral researcher at the Mount Sinai School of Medicine in New York, said.

That may affect the effectiveness of drugs, treatments and vaccinations usually designed to treat whole populations. The researchers said the link between antibody makeup and ethnicity surfaced when they screened the chromosomes of 425 people of Asian, African and European descent for several DNA insertions and deletions.

The findings "could mean that past environmental exposures to certain pathogens caused DNA insertions or deletions in different ethnic groups, which could impact disease risk," Watson said. "Our results demonstrate that antibody studies need to take into account the ethnicity of DNA samples used."

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DNA sampling nabs Dutchman for murder

Posted: at 9:45 pm

Mass DNA sampling has led to the jailing of a father-of-two for the shocking rape and murder of a teenaged girl in a rural part of The Netherlands 14 years ago.

A court in northern city Leeuwarden on Friday jailed farmer Jasper Steringa for 18 years for the 1999 murder of 16-year-old Marianne Vaatstra. The crime had initially been blamed on asylum seekers.

Steringa, 45, lived for 13 years less than two kilometres from the field where Vaatstra's body was found, raped, strangled and with her throat cut.

She disappeared during the night of April 30 as she returned home by bicycle from celebrating the Dutch national day, Koninginnedag.

The investigation went cold and was only reopened after changes in Dutch law last year allowed police to identify a suspect by comparing DNA found on a crime scene with genetic material indicating a family relation.

Around 7300 men turned up voluntarily in September to specially set-up DNA-testing stations in the area to have the inside of their cheeks swabbed.

One of those men was Steringa, who reportedly knew the game was up because, thanks to the change in the law, a DNA test of one of his relatives would also have identified him.

Steringa confessed to the crime and said that he hadn't handed himself in before because he wanted to see his children grow up.

'The probability of a man chosen at random having the same DNA is around one in 1,500 billion. That effectively means that the suspect's DNA is the same of Jasper S.,' the court said in a statement.

At the time of the murder, fingers were pointed at two men from Iraq and Afghanistan who had shortly before left a nearby centre for asylum seekers.

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