Category Archives: Transhuman News

Hannibal For King Team DNA - [Featuring: Prophecy Workout] - (15 Degrees Fahrenheit)
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Hannibal For King

Lobotomic Garden - Mutant DNA
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Lobotomic Garden - Mutant DNA - Video

Little Mix - DNA Italian special event (20 april 2013) Milan (FULL)
The Girls live show at Magazzini Generali / Milano / Italy songs: Wings, DNA, Change Your Life How Ya Doin #39;?

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Little Mix - DNA Italian special event (20 april 2013) Milan (FULL) - Video

MASS DNA sampling led to the jailing yesterday of a father-of-two for the shocking rape and murder of a teenaged girl in a rural part of the Netherlands 14 years ago.

A court in the northern city of Leeuwarden jailed farmer Jasper Steringa for 18 years for the 1999 murder of 16-year-old Marianne Vaatstra. The crime had initially been blamed on asylum seekers.

Steringa, 45, lived for 13 years less than 2 kilometers from the field where Vaatstra's body was found, raped, strangled and with her throat cut.

She disappeared during the night of April 30 as she returned home by bicycle from celebrating the Dutch national day.

The investigation went cold and was only reopened after changes in Dutch law last year allowed police to identify a suspect by comparing DNA found on a crime scene with genetic material indicating a family relation.

Around 7,300 men turned up voluntarily in September to specially set-up DNA-testing stations in the area to have the inside of their cheeks swabbed. One of those men was Steringa, who reportedly knew the game was up because, thanks to the change in the law, a DNA test of one of his relatives would also have identified him. Steringa confessed to the crime.

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Eastday-DNA sampling snares rapist-murderer

Public release date: 22-Apr-2013 [ | E-mail | Share ]

Contact: Amy Molnar sciencenewsroom@wiley.com Wiley

A new analysis has found that the loss or amplification of particular DNA regions contributes to the development of prostate cancer, and that patients with two of these DNA changes have a high likelihood of dying from the disease. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study provides valuable information on the genetics of prostate cancer and offers insights into which patients should be treated aggressively.

Cells can become cancerous when they lose or amplify pieces of DNA containing important genes. Using a method that can detect these genetic changes in cells from prostate tumors from 125 patients, Jianfeng Xu, MD, DrPh, Director of the Center for Cancer Genomics at the Wake Forest School of Medicine in Winston-Salem, and his colleagues at Wake Forest, Brady Urological Institute of Johns Hopkins Medical Institutions, and Karolinska Institute of Sweden found that changes in 20 gene regions likely contribute to prostate cancer development. Four of these regions had not been reported before. Importantly, changes in seven of the 20 regions were linked with early death from prostate cancer. Also, patients whose cancer cells had a loss of the PTEN gene and an amplification of the MYC gene were more than 50 times as likely to die from prostate cancer than other patients who had similarly staged tumors and prostate-specific antigen levels at the time of diagnosis. Analyses of 333 tumors from additional patients confirmed the link between PTEN and MYC and prostate cancer lethality.

In addition to providing new information about the genetic changes involved in the development and progression of prostate cancer, the findings may help guide doctors as they weigh different treatment options for patients with the disease. "For example, prostate cancer patients who have DNA copy number alterations at PTEN and MYC may not be appropriate candidates for active surveillance and should be treated intensively," explained Dr. Xu.

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URL Upon publication: http://doi.wiley.com/10.1002/cncr.27954

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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Particular DNA changes linked with prostate cancer development and lethality

One of the most momentous discoveries of the 20th century will be remembered this week 60 years after scientists revealed the structure of DNA.

On Thursday a memorial to British biologist Francis Crick will be unveiled by American James Watson at the university where they worked six decades ago.

Together they described the double-helix structure of DNA in a seminal paper published in the journal Nature on April 25, 1953. Their work set the stage for a molecular revolution, opening up vast new avenues of understanding about the genetic code, or "Book of Life".

Dr Watson, now retired, went on to direct the US arm of the Human Genome Project from 1988 to 1992. In 2000 the HGP published a first draft of the complete human genetic code, marking another historic turning point.

Friends, former colleagues and admirers of Professor Crick, who died in 2004, will gather at his former Cambridge University college, Gonville and Caius, to view the unveiling. The event will be followed by a series of talks and tributes by leading experts and colleagues, including Dr Watson.

Dr Watson and Prof Crick's work on the structure of DNA earned them the Nobel Prize for Medicine in 1962, which they shared with colleague Maurice Wilkins from King's College London.

The two men showed showed how DNA stored information using a four-letter molecular alphabet consisting of the letters A, T, C and G arranged in a double-helix. Three billion copies of these letters make up the entire human genome. Some are sorted into sequences called genes that provide the software instructions for making proteins and allow parental traits to be inherited.

Before the structure of DNA was unscrambled no one had a clear idea how genetic replication - one of the cornerstones of life - worked.

The discovery acted as a springboard that scientists have been jumping off ever since. Genetic research has transformed our understanding of the causes of cancer and other diseases and led to a multiplicity of new targeted treatments.

Dr Ted Bianco, acting director of the Wellcome Trust, which provided much of the funding for the Human Genome Project, said: "The discovery of the double helix is one of many great British breakthroughs in science. And we continue to be world leaders in the fields of genetics and genomics as these disciplines have grown and matured."

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DNA structure anniversary marked