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Category Archives: Transhuman News
DNA Samples, Background Checks Among Laws Starting Monday
Posted: July 1, 2013 at 12:01 pm
DES MOINES, Iowa - Here are some of the measures passed by the split-control Iowa General Assembly during the 2013 legislative session and signed by Gov. Terry Branstad that will take effect July 1:
DNA SAMPLES THE LAW: Iowa scofflaws could face penalties if they run afoul on new offenses for possessing or operating a radar-jamming device or removing a police communications device; also lawbreakers convicted of an aggravated misdemeanor will have to submit a DNA sample to authorities. WHAT IT DOES: Currently, offenders convicted of felonies are required to provide a DNA sample to be entered into the national databank. Law enforcement officials wanted the changes to enhance public safety, while civil libertarian and social justice advocates opposed the changes are government intrusion into Iowans personal lives and unnecessary additions to the criminal code.
REINVESTMENT DISTRICTS THE LAW: Communities will be able to establish reinvestment districts to capture shares of state sales tax and local hotel/motel fees to help fund big-ticket attractions or projects. WHAT IT DOES: The split-control Legislature achieved bipartisan support for cities and counties to designate special 25-acre development zones and use a share of sales tax and hotel-motel tax revenues to assist private projects of at least $10 million as a way to spur big ideas.
BACKGROUND CHECKS THE LAW: All school employees must undergo a background check of the sex offender registry, child abuse registry, and the dependent adult abuse registry before being hired. WHAT IT DOES: For current employees, the law change requires a school district to establish a policy which would require these employees to undergo the record check at least every five years after their date of hire. If a current employee is found to be on one of the registries, that would be grounds for suspension pending a termination hearing by the school board.
LIABILITY PROTECTION THE LAW: Land owners will have expanded liability protections for farm tours. WHAT IT DOES: The change is designed to abrogate an Iowa Supreme Court decision holding that farmers who offer educational tours are not shielded from personal injury lawsuits under Iowas recreational use law. The court ruled 5-2 last February that the owners of a dairy farm could be sued by a chaperon injured when she fell through a hole in a hayloft during a kindergarten class field trip.
OTHER LAWS OF NOTE -Students attending a state university in Iowa will not see an increase in their in-state resident tuition for the next school year. - Students attending private colleges and universities in Iowa will be eligible to receive up to $5,000 annually in Iowa tuition grants. - Iowans possessing cellphones will pay an extra 35 cents a month surcharge for E-911 service, putting them on even keel with the $1 assessed monthly per land-based telephone line. - Most Iowa drivers will be able to renew their Iowa licenses online as well as only do it every eight years rather than five. - Employees operating ice cream trucks or other mobile businesses catering to kids and school employees will be subject to background checks. - A new sex offender exclusion zone is created making it illegal for a sex offender to operate, manage, be employed by or act as a contractor or volunteer at a business that operates an ice cream truck. - Prevention and control measures are implemented for aquatic invasive species and disbursement of plants or seeds of garlic mustard, oriental bittersweet, Japanese knotweed and Japanese hop is prohibited. - Livestock producers will be allowed to mothball production facilities rather than tear them down if they downsize or temporarily suspend their operations and the change is approved by the Iowa Department of Natural Resources.
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DNA Samples, Background Checks Among Laws Starting Monday
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DNA tests provide no leads in ’77 Bucks case
Posted: at 12:01 pm
ASSOCIATED PRESS Posted: Monday, July 1, 2013, 12:18 AM
PROSECUTORS in Bucks County say long-awaited DNA tests in a murder case from 3 1/2 decades ago have shed little light on who killed the victim.
Matt Weintraub, Bucks County's chief of prosecution, told the Bucks County Courier Times that the test results were inconclusive "due to the degradation of the evidence."
Given that, Weintraub said the 1977 murder of 20-year-old Shaun Ritterson of Bristol will remain open but will no longer be an active investigation.
"Personally, I'm disappointed," he said. "But professionally, I'm satisfied that we've done all that we can do to solve this case and bring some finality to it."
Ritterson was found stabbed and disemboweled on a Buckingham hillside in June 1977. Numerous people were questioned, but no arrests were ever made.
Weintraub told relatives of the victim that he shared their disappointment and said "they have handled this with grace and dignity."
Family members said the renewed focus on the case had reopened old wounds but they had hoped it would bring a conclusion.
"You never have closure in something like this," said the victim's sister, Grace Gordon. "Each day you learn to deal with it in your own way. Whether it's sadness, anger, or recalling happy memories, or crying with my mom. Either way, it would never have brought closure. A wound like this never heals."
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DNA tests provide no leads in '77 Bucks case
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DNA particles in the blood may help speed detection of coronary artery disease
Posted: at 12:01 pm
Public release date: 1-Jul-2013 [ | E-mail | Share ]
Contact: Maggie Francis maggie.francis@heart.org 214-706-1382 American Heart Association
DALLAS, July 1, 2013 DNA fragments in your blood may someday help doctors quickly learn if chest pain means you have narrowed heart arteries, according to a new study published in the American Heart Association journal Arteriosclerosis, Thrombosis, and Vascular Biology.
The study involved 282 patients, ages 34 to 83, who reported chest pain and were suspected of having coronary artery disease. Researchers used computed tomography imaging to look for hardened, or calcified, buildup in the blood vessels that supply the heart. Blood samples also were tested for bits of genetic material. Release of small DNA particles in the blood occurs during chronic inflammatory conditions such as coronary artery disease.
Higher levels of DNA particles in the blood were linked to high levels of coronary artery calcium deposits. These particles are potentially markers of disease, and may eventually help identify patients with severely narrowed coronary arteries, predict how many coronary vessels were affected, and even whether a patient is likely to suffer a serious heart problem or heart-related death.
"If those markers are proven to be effective specific and sensitive they may improve medical care in terms of identifying patients at risk sooner," said Julian Borissoff, M.D., Ph.D., lead author of the study and postdoctoral research fellow at Boston Children's Hospital and Harvard Medical School. "And so the patients may go on treatment sooner."
The scientists noted that larger studies, following more patients for longer periods, are needed to see how precisely these markers might identify patients at risk for developing coronary artery disease. Almost half of the patients studied were followed for a year and a half or longer.
If the markers do pan out, they have the potential to help doctors efficiently pinpoint which patients with chest pain are likely to have coronary artery disease rather than some other problem causing the discomfort, Borissoff said. Currently, a time-consuming and costly battery of tests is used to determine whether the heart is at risk, he said.
It is plausible to think that the DNA particles themselves might contribute to the progression of atherosclerosis and the risk of dangerous blood vessel blockages, the study's authors wrote. "The more the ongoing cell death, which is normal with inflammation, the more DNA enters the circulation and more plaque builds up," Borissoff said. "Cells get damaged, and the products released from the damaged cells can cause even more damage and inflammatory responses."
The researchers are testing the DNA particle components further, he said, to see which ones are most sensitive and to understand more about how their levels might vary for instance, during different stages of progression of atherosclerosis, or during a treadmill test, or after treatment for a heart attack.
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DNA particles in the blood may help speed detection of coronary artery disease
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Genome BC and BC Cancer Foundation: Changing the Face of Cancer Treatment; Genomic Research into Lymphoid Cancer …
Posted: at 12:00 pm
VANCOUVER, BRITISH COLUMBIA--(Marketwired - Jun 26, 2013) -
Note to editors: B-roll video and still photographs are available for download at http://bccancerfoundation.com/media-resources
Researchers at the BC Cancer Agency will receive $10 million investment to further their work in finding a cost-effective, genomic approach to treat lymphoid cancer patients. The substantial support from Genome British Columbia, the BC Cancer Foundation, Genome Canada and the Canadian Institutes of Health Research (CIHR) will dramatically advance therapies for patients diagnosed with the disease: lymphoid cancers are the fourth most common cancer in BC.
"This funding allows BC to become a real world laboratory to show how we can use genomic analysis cost-effectively to treat more cancer patients in a way that can readily be duplicated elsewhere around the world," says Dr. Joseph Connors, project leader and clinical director at the BC Cancer Agency's Centre for Lymphoid Cancer. "It brings together a culmination of decades of meticulous record-keeping with cutting-edge technology to maximize our knowledge about lymphoid cancers."
Dr. Connors adds that recent research has shown that genomic sequencing can recognize specific lymphoid cancers that are often untreatable with current technology. These cancers could be treated more effectively using personally designed treatments - and Dr. Connors and his team intend to provide this type of treatment in the near future.
Each patient's cancer is distinct; therefore treating them with a one-size-all approach is not efficient or cost effective and can put patients through unnecessary treatments that will not be of benefit to them. Personalized cancer treatment means determining the specific genetic characteristics of a patient's cancer and prescribing therapies that are customized for the unique molecular makeup of their cancer. Genomic sequencing is now able to accurately and quickly decode the entire genetic instructions in malignant and normal cells. This opens the possibility that doctors will be able to use this information to choose treatments that are specifically designed for that individual patient's cancer.
The research project will study four specific lymphoid cancers of which there are more than 500 cases each year in our province. In more than half of these cases primary treatment fails, and associated costs of secondary treatment run over $60,000 and this amount is often exceeded in just the cost of anti-cancer drugs alone. Personalized medical care employing sophisticated genomic techniques may dramatically reduce this cost: in the last few decades a number of new drugs have come on the market to improve patient outcomes but a drastically new approach is now required in order to apply the genomic information now available. Core components of the project will include careful analysis of all the costs that result from personalized lymphoid cancer care and development of economic analytic tools that enable healthcare planners to assess the economic impact of applying similar techniques to treating other cancers and other diseases.
"Genome BC's investment into this work is farsighted-analysis of this cancer will provide a revised lymphoma treatment model for our province and analytical tools that can be applied to other types of the disease," says Dr. Alan Winter, President & CEO of Genome BC. "This funding closes a gap between novel research and real-time clinical application."
"The BC Cancer Foundation is proud to support this initiative as the BC Cancer Agency's Centre for Lymphoid Cancer is on a trajectory to establish a world-leading model of advanced care, which will truly benefit patients diagnosed with lymphoid cancer," says Douglas Nelson, President & CEO, BC Cancer Foundation.
The research project Personalized treatment of Lymphoid Cancer: British Columbia as a Model Province is funded through Genome Canada's 2012 Large-Scale Applied Research Project Competition.
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Cellectis Has Successfully Engineered the Genome of Photosynthetic Algae with a View to Biofuel Production
Posted: at 12:00 pm
PARIS--(BUSINESS WIRE)--
Regulatory News:
Cellectis (ALCLS.PA), the genome engineering specialist, announced today that it has successfully used engineered nucleases to genetically reprogram diatoms with a view to producing biofuels. This technological breakthrough was revealed by Dr. Fayza Daboussi, the Cellectis Groups VP of Synthetic Biology and Technology of Cellectis Group on June 26 at the Molecular Life of Diatoms meeting in Paris, France.
The results presented at the Molecular Life of Diatoms meeting by Dr. Fayza Daboussi, who led the study, demonstrate the strength of Cellectis engineered nucleases for efficient gene inactivation and/or gene insertion in diatoms. Cellectis has generated a lipid-rich diatom which highlights the significance of this breakthrough. This work will lead to new opportunities in synthetic biology and especially biofuel production from photosynthesis and CO2.
Cellectis develops and produces engineered site-specific endonucleases such as meganucleases and TALENTM which have recently emerged as the most powerful approach in genome engineering1. By targeting specific sequences within diatoms genome, these nucleases can be used to accurately insert, correct, or inactivate specific genes. This first step offers a new opportunity for synthetic biology in microorganisms previously inaccessible to rational genome engineering.
With the recent whole genome sequencing of several diatom species such as Thalassiosira pseudonana and Phaeodactylum tricornutum, a new era of post-genomics research has begun. Full sequencing provides fresh opportunities to improve our fundamental understanding of the biology of diatoms, and to build a molecular foundation for new industrial applications. However the tools available for generating industrial strains are still based on non-targeted over-expression or gene repression using RNA interference (2&3). This is where Cellectis innovations and technologies can offer new perspectives.
About Cellectis
Founded in France in 1999, the Cellectis Group bases its work on highly specific DNA engineering technologies. Its application sectors are human health, agriculture and bio-energies. Cellectis was co-founded by Andr Choulika, its Chairman and CEO, and is now one of the worlds top companies in the field of genome engineering, with revenue of $27million in 2012. Leading the field of pluripotent stem cells, Cellectis has developed expertise in drug discovery, toxicity testing, and regenerative medicine. Cellectis has a solid background in the large-scale handling of stem cells up until their maturation and differentiation into functional cell types. We employ a workforce of 230 people at 5 sites worldwide: New Brighton (Minnesota) & Cambridge (Massachusetts) in the United States, Gothenburg in Sweden, and Paris & Evry in France.
The Group has signed more than 100 industry agreements with pharmaceutical, agrochemical, and biotechnology companies. Our clients and partners include University College London (UCL), the National Institutes of Health (NIH), Novo Nordisk, the Center for iPS Cell Research and Application (CiRA) of Kyoto University, AFM, Novartis, BASF, Bayer, and Limagrain. Since 2007, Cellectis has been listed on the NYSE Euronext Alternext market (ALCLS.PA) in Paris.
For more information, visit our website: http://www.cellectis.com.
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Jetsetter: Australia, censorship, and the banning of ‘Saints Row IV’
Posted: at 12:00 pm
Great artists will tell you on the regular that the key to making great art is to make it for yourself first, but thats not always a realistic end point for people creating art for a living especially when youve got to think about the audience. Do you make something for everyone globally, or do you make something for a small group? How do you actually make something that speaks to everyone?
Jetsetter, Digital Trends weekly column devoted to import gaming and game development outside the US, exists because its impossible to make art that truly speaks to everyone. Even if a game doesnt directly speak to you, even if it wasnt made with you in mind, that doesnt mean it isnt worth experiencing. Broaden those horizons!
Forget figuring out how to navigate the murky waters of finding your audience when youre designing a game, its hard enough just making sure your game can even legally get released around the world. Just because the ESRB in the US says a game is rated M for Mature audiences, that doesnt mean everyone agrees. Australia has long had a reputation for ferocious censorship of video games. It was only in 2012 thatthe country started rating games for audiences 18-years-old and up. Before that, games like Grand Theft Auto 4 were simply barred classification in the country and never legally released. Even with R18+ classification, though, Australia is still stopping games from release. Volitions Saints Row IV was refused just this past week due to implied sexual violence and illicit or proscribed drug use related to incentives or rewards.
It is baffling what Australias ratings board does and does not consider appropriate. Drug use? Thats right out. A game like Ninja Gaiden 3: Razors Edge, a game where gutting human beings is the whole point, is just fine.
Russia loves its MMOs, just look at the crazy following for World of Tanks in the country. Last December, 600,000 Russian citizens were playing that gameat the same time. Russian developer Allods Team recognizes a good thing when it sees it, hence why its developing Skyforge, a new fantasy MMO that actually looks pretty swell. In a market glutted with World of Warcraft knock offs, generic Korean fantasy MMOs, and dwindling online populations, a polished but familiar game like Skyforge actually stands out.
As reported by Eurogamer, Skyforge has some help in the form of Obsidian Entertainment, the famed RPG developer behind games like Star Wars: Knights of the Old Republic II. Obsidian is busy cracking away on games like Project Eternity, but its taking time out to help advise Allods on how to bring Skyforge to the rest of the world. Its a good example of what needs to be done to rethink games for the world stage.
We love Atlus here at Jetsetter. A lot. So, so much. And not just because of its recent hits like Persona 4 and Catherine. We love Atlus from way back, like when they were pumping out import-only Sega Saturn games like Purikura Daisakusen. So the news that Atlus parent company Index is not only under investigation for fraud, but may also have to declare bankruptcy was distressing. What will happen to Persona 5?! Since Atlus is one of the healthiest parts of Indexs business, with a host of popular IPs with global appeal, its likely that the studio will be acquired by another company rather than shuttering alongside the parent should it come to that.
Seriously, go play Purikura Daisakusen! And Super Valis IV for Super Nintendo! And all the other amazing stuff Atlus has been pumping out for the past few decades.
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Jetsetter: Australia, censorship, and the banning of ‘Saints Row IV’
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transhuman nature (29.06 Saarbrücken Kitu Klub) – Video
Posted: at 11:59 am
transhuman nature (29.06 Saarbrcken Kitu Klub)
https://www.facebook.com/transhumannature.music ** http://www.whywelikeyou.de.
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Crysis 3 – Mission 1 – Post Human – Part 1 – Free Prophet – HD Let’s Play Gameplay Walkthrough – Video
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Crysis 3 - Mission 1 - Post Human - Part 1 - Free Prophet - HD Let #39;s Play Gameplay Walkthrough
Follow me on Facebook or Twitter for news about gaming, technology and updates of my Youtube channel. Welcome to the new walkthorugh of Crysis 3. Mission 1: ...
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Crysis 3 – Mission 1 – Post Human – Part 2 – Escape – HD Let’s Play Gameplay Walkthrough – Video
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Crysis 3 - Mission 1 - Post Human - Part 2 - Escape - HD Let #39;s Play Gameplay Walkthrough
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Crysis 3 - Mission 1 - Post Human - Part 2 - Escape - HD Let's Play Gameplay Walkthrough - Video
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Crysis 3 – Mission 1 – Post Human – Part 4 – Randevouz – HD Let’s Play Gameplay Walkthrough – Video
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Crysis 3 - Mission 1 - Post Human - Part 4 - Randevouz - HD Let #39;s Play Gameplay Walkthrough
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Crysis 3 - Mission 1 - Post Human - Part 4 - Randevouz - HD Let's Play Gameplay Walkthrough - Video
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