Category Archives: Transhuman News

SALEM, Mass. A forensic scientist testified Thursday that DNA matching both accused murderer Joel Monegro and his deceased wife, Yesenia, were found on bloody knives seized as evidence from their Lawrence apartment.

Amy Joy, who was previously employed by the Massachusetts State Police Crime Lab, defined DNA for jurors as the blueprint that makes us who we are.

Joy was another prosecution witness who testified to testify in Salem Superior Court. Thursday was the third day of the criminal trial.

Monegro, 35, is charged with murdering Yesenia, 28, on May 28, 2018, in their Doyle Street apartment.

Answering questions posed by Assistant District Attorney Kate MacDougall, Joy said DNA taken from blood samples on two knives and fingernails found in the apartment belonged to both Joel and Yesenia.

MacDougall, in her opening statement Tuesday, said Yesenia suffered 30 stab wounds to her face, neck, torso, arms and back. Despite the slash wounds, she was able to tell a Lawrence police officer it was Monegro, her high school sweetheart and husband, who stabbed her.

Yesenia was pronounced dead a short time later at a Boston hospital.

The attack occurred after Yesenia learned Joel was having a second child with Toni Marie Eaton, a woman hed been having an affair with, she said.

Eaton was about four months pregnant when Yesenia was killed. Eatons first child with Monegro was born in September of 2016, she testified on Wednesday.

However, defense attorney Kevin Mitchell, in his opening statement, said Monegro acted in self defense.

He said Monegro, who carries a knife for work purposes, went to the apartment that day to meet Yesenia and give her some money.

If convicted of first degree murder, Monegro faces life in prison without the possibility of parole.

In addition to Joy, State Police Lt. Michael Perry also testified Thursday. He worked in crime scene services in May 2018.

MacDougall removed two knives from evidence boxes and Perry identified them as the weapons collected from the Doyle Street apartment and tested.

The trial is expected to stretch into early next week.

Follow staff reporter Jill Harmacinski on Twitter @EagleTribJill.

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Forensic scientist testifies husband and wife's DNA found on knives - Eagle-Tribune

Dublin, March 24, 2022 (GLOBE NEWSWIRE) -- The "Viral Vectors And Plasmid DNA Global Market Report 2022: By Product, By Application, By Disease, By End-User" report has been added to ResearchAndMarkets.com's offering.

The global viral vectors & plasmid DNA market is expected to grow from $0.69 billion in 2021 to $0.80 billion in 2022 at a compound annual growth rate (CAGR) of 14.8%. The growth is mainly due to the outbreak of COVID-19 and requires targeted delivery of the drug to treat affected patients, resulting in a surge in demand for viral vectors & plasmid DNA. The market is expected to reach $1.38 billion in 2026 at a CAGR of 14.8%.

The main types of products in viral vectors & plasmid DNA are plasmid DNA and viral vectors. A plasmid is a single-stranded, circular DNA molecule which is different from the chromosomal DNA of a cell. Plasmids are found organically in bacterial cells as well as in certain eukaryotes. Plasmid genes frequently confer genetic benefits to bacteria, such as antibiotic resistance. The different diseases include infectious diseases, genetic disorders, cancer, others and is used in gene and cancer therapies, viral infections, immunotherapy, formulation development, others. The several sectors include research institutes, biopharmaceutical and pharmaceutical companies.

North America was the largest region in the viral vectors & plasmid DNA market in 2021. Middle East is expected to be the fastest growing region. The regions covered in this report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The rise in the global incidence of cancer is driving the viral vector & plasmid DNA market. The major causes for most cancers include obesity, smoking, alcohol, improper eating habits. According to American cancer society 2020, an estimated 1.8 million new cancer cases diagnosed and 606,520 cancer deaths in the United States. Furthermore, according to the American Cancer Society, in 2019, around 606,880 deaths were caused in USA due to prevalence of the cancer. Cancer Research UK predicts that there will be 27.5 million new cases of cancer each year by 2040. The rise in the global incidence of cancer is expected to boost the demand for the viral vectors and plasmid DNA market over the coming years.

The unaffordable cost of gene therapies is a major challenge in the viral vectors & plasmid DNA market. The prices of gene therapies range between $0.2 million to $2.1 million. The high price is due to various factors like government regulations, production costs, and so on. Therefore, the unaffordable cost of gene therapies is limiting the viral vector & plasmid DNA market growth.

The report focuses on viral vectors & plasmid DNA market which is experiencing strong growth. The report gives a guide to the viral vectors & plasmid DNA market which will be shaping and changing our lives over the next ten years and beyond, including the markets response to the challenge of the global pandemic.

Report Scope

Markets Covered:

By Product: Plasmid DNA; Viral VectorsBy Application: Gene And Cancer Therapies; Viral Infections; Immunotherapy; Formulation Development; OthersBy Disease: Infectious Diseases; Genetic Disorders; Cancer; OthersBy End User: Research Institutes; Biopharmaceutical And Pharmaceutical Companies

Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA

Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa

Time series: Five years historic and ten years forecast

Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,

Data segmentations: country and regional historic and forecast data, market share of competitors, market segments

Companies Mentioned

For more information about this report visit https://www.researchandmarkets.com/r/vk8zew

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Viral Vectors and Plasmid DNA Global Market (2021 to 2026) - Featuring FUJIFILM Diosynth Biotechnologies, Thermo Fisher Scientific, Renova...

Nobody should want to play the Bucks in the playoffs. It's been a bit of an up and down season for the defending champs, but they're starting to round out into form and get healthy with the regular season drawing to a close.

Few teams, if any, can match Milwaukee's trio of stars.

Giannis Antetokounmpo is playing at an MVP level once again, posting 30-12-6 on a nightly basis while flirting with the scoring title and the greatest PER in NBA history. Khris Middleton got off to a slow start by his standards but is now playing his best basketball of the season. And while Jrue Holiday was the only one of the three to not be named an All-Star this season, he had a legitimate reason to feel as though he was snubbed.

They already proved they can win it all together. This season, they're even more in sync, especially in crunch time. Not that Antetokounmpo, Middleton and Holiday need a whole lot of help to get going, but there is one particular way the Bucks weaponize their three stars at the same time at the end of games.

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The play itself is pretty simple: Holiday brings the ball up the court while Antetokounmpo and Middleton make their way to the elbow. The two other Bucks park themselves on the perimeter to maximize spacing.

From there, Antetokounmpo sets a screen for Middleton...

...and that is where the fun begins.

Middleton is Milwaukee's most versatile shooter. He's at his best when he's breaking defenders down and raining in silky smooth midrange jumpers, but he's equally capable of stepping out to the 3-point line. So if his defender gets caught up in Antetokounmpo's screen, he can do his best Klay Thompson impression bypopping out to the perimeter, like so:

If Middleton doesn't get open, he usually clears out to the 3-point line, paving the way for the Bucks to flow into a pick-and-roll with Holiday as the ball handler and Antetokounmpo as the screener.

Holiday has quietly been one of the league's most efficient pick-and-roll scorers this season. Nobody is going to confuse him with Stephen Curry, but Holiday is a legitimate threat to score from all three levels.

According to NBA.com, Holiday has connected on 40.7 percent of his pull-up 3-point attempts this season. Ducking underneath screens against him isn't really a safe option. That's a scary development for an already proven championship point guard.

He's also been dynamite from midrange, canning well over half of his looks from that distance.

And Holiday is one of the better finishers at his position around the basket. Just ignore him, uhh, blowing this layup:

If Holiday isn't in a position to score, Antetokounmpo or one of Milwaukee's shooters probably are. Antetokounmpo has become one of the league's most feared rollers and the Bucks have several floor-spacers to choose from on their roster in Wesley Matthews, Grayson Allen, Pat Connaughton, Jordan Nwora, Bobby Portis and Brook Lopez.

Then there's option No. 3, which is by far the scariest: Antetokounmpo gets the ball at the elbow.

Everyone in the world knows that Antetokounmpo wants to get to the basket only Nikola Jokic and Ja Morant have outscored himin the paint so far this season and yet there's little anyone can do to stop him. He's too quick and shifty for most centers and far too strong for most forwards.

Building a wall has become most teams' only hope of even having a shot at slowing him down, but with four perimeter players surrounding him, keeping him out of the paint is much easier said than done. And preemptively building that wall before he touches the ball opens up the aforementioned Middleton and Holiday to get to work.

There's more where all that came from as well.

As you may have noticed in some of the examples above, Middleton will sometimes screen for Holiday before he clears out to the perimeter, giving Holiday's defender yet another obstacle to fight through. Antetokounmpo is going to look to score more often than not when he gets the ball at the elbow, but he can easily dribble the ball out to Holiday or Middleton for a handoff if teams pack the paint. Holiday can even get involved as a screener to get Antetokounmpo a more favorable mismatch.

Basically, the options are almost endless, and they always put one of Antetokounmpo, Middleton and Holiday in position to do what they do best.

It's no wonder why it's become Milwaukee's go-to play in the clutch. Best of luck to anyone trying to stop it.

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Championship DNA: This Bucks' go-to play in the clutch could lead to another NBA Finals - Sporting News

Organisations that constantly evolve benefit from creativity, ingenuity, and collaboration, experts from TAFEP note.

This article on continuous evolution is the third installment of the five-part series on the building blocks to develop the DNA of a progressive employer. Read parts one and two here.

Change is not just a management buzzword; it is a necessity for business survival in a world of disruptions. Keeping pace with change requires organisations to continuously evolve, and this is identified as one of the five building blocks to develop the DNA of a progressive employer in a study commissioned by the Tripartite Alliance for Fair and Progressive Employment Practices (TAFEP).

Organisations that embrace continuous evolution continually improve their processes, programmes, and practices to achieve superior business outcomes. They experiment with new ways of working to improve the status quo, and use data to track and measure effectiveness. More importantly, they bring their people along the change journey.

Examples of organisations that have been actively changing their business processes or products are, as expected, some of Silicon Valleys big tech players. But in what may come as a sweet surprise, Singapores oldest sugar manufacturer is also transforming.

Founded in 1947, Singapores Cheng Yew Heng Candy Factorys family business has evolved in the last seven decades from producing sweet snacks like sour plum candies to manufacturing rock, red and black sugars for global export.

It modernises the business with automation to increase productivity and instils in employees a culture of learning and innovation. This accelerated when third-generation leader John Cheng joined the business in 2008.

For instance, he sent employees for courses to upgrade their skills, created new product lines to provide jobs for staff whose work have been replaced by machinery, and introduced a system of employee benefits.

On the other side of the world, US tech companies also charted new frontiers. For example, Netflix evolved from a DVD rental company to a giant subscription streaming service and production company with over 200mn subscribers.

Netflixs success could be attributed to its culture, where employees are trusted to take smart risks, make and own decisions based on what they think is best for the organisation, and have candid exchange of constructive feedback at all levels to embrace different perspectives, make better decisions, and understand how one can improve, learn, and adapt more quickly.

How can you develop a company culture of continuous evolution? Here are some tips to get started:

#1 Encourage experimentation, learning, and discovery

Both employers and employees must be curious to challenge norms and assumptions, without fear of failure and view setbacks as opportunities to learn.

This can be achieved with leaders who do not play the blame game, and instead find out what went well to identify areas for refinement. To further encourage employees to test new ideas, leaders should recognise employees efforts by rewarding the innovative spirit that resulted in both achievements and those with less than sterling results.

Leaders also ought to instil a growth mindset and ensure that there are fair and relevant training opportunities for employees to acquire new skillsets to keep up with changes.

#2 Ensure all employees contribute

Giving employees a voice in initiating change helps build ownership and makes them more likely to support change and champion it.

Empower your employees creativity by fostering collective participation, where everyone feels responsible to contribute and proactively identify areas for change.

This can be done by giving them outlets to pinpoint areas where they can improve and ideas to do so. More importantly, listen to them and develop line managers to become your change-makers for better engagement and business growth.

#3 Put in place a clear process to facilitate change

Clear processes and guidelines help reduce uncertainty, enabling employees to act with greater confidence.

For example, periodic reviews to track progress and analyse results, especially during the experimentation phase or when a pilot initiative is launched will help promote agility in making adjustments and improvements along the way, and ramping up internal communications to employees provide clarity and ensure that they feel more involved in the process.

Organisations that embrace a culture of continuous evolution enable creativity, ingenuity, and collaboration to flourish, and are agile in responding to organisational changes. This will lead to business longevity and sustained success.

[View part two of the series:Decoding the DNA of progressive employers: How to value employee voice]

Learn more about instilling a culture of continuous evolution at your workplace by downloadingTAFEP'sBeyond 20/20: DNA of Progressive Employers.

Image / 123RF

Follow us onTelegramand onInstagram@humanresourcesonlinefor all the latest HR and manpower news from around the region!

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Decoding the DNA of progressive employers: How to continuously evolve for superior business outcomes - Human Resources Online

Getting a DNA test is exciting, to say the least. But its an excitement that can be interpreted in several ways.

For instance, do you want to learn about your heritage and where you come from? Nice, go get it. Do you, however, accept that there is a non-zero chance that you will also learn something you wish you have never learned at all? You know, a dark family secret like your dad isnt really your dad, or that you were adopted, or the fact that you have married your first cousin?

Speaking of which, a Redditor recently shared a story of how he ended up figuring the latter out by simply gifting his wife a DNA test kit.

More info: Reddit

Image credits: Vivian Evans (not the actual photo)

Reddit user u/PM_MeMyPassword recently went to the TIFU, or Today I Effed Up, subreddit with quite a unique story.

So, both OP and his wife grew up in a small town in the South. Both of their families have been living there for quite some time now. Both of these lovely individuals also had previous marriages and 3 kids each from those marriages, and there are no plans for any more now that they are together.

Last year OP got his wife an Ancestry DNA kit as a gift. Apparently, she wanted to know more about her European roots, and her sister decided to do the same.

Image credits: u/PM_MeMyPassword

As you might have guessed by this point, the results came in and the test began making connections they didnt quite expect. Apparently, OPs wife was genetically related to his mother, oldest son, his uncle this is where most people in this situation would get a sense of impending doom.

So, they asked the wifes mother about the relations here, and she started crying and explains that when she was younger, she once overheard someone claim that her father is not who she always thought her dad was. She simply put it out of her mind, convinced herself it was a mere rumor. Turns out, not quite.

Image credits: u/PM_MeMyPassword

OP calls his mom, asks if she ever heard such a rumor, and mom goes quiet. After a brief moment, she confirms that she has heard rumors, and her mother actually thought it was true. His grandpa was known to be a womanizer back then.

So, they follow up the information on 23&Me, a genomics and biotechnology company who do DNA tests, and again they get confirmation that the wife shares a great grandparent with his oldest son.

More of us are now getting tests on the same platform but it appears a WW2-era secret has come to light, concluded OP with a joke.

Image credits: u/PM_MeMyPassword

He also gave some updates to the post, like pointing out that his wife was laughing at first, but the reality of it all caught up to her, and that neither he, nor his wife are thinking of changing anythingthey are in love and they want to stay that way.

In under a day, the post got 38,000 upvotes and over 30 Reddit awards, including the subreddits exclusive TIFU award, and generated over 2,700 comments.

Image credits: u/PM_MeMyPassword

In the comments, people shared their own Surprise! Were related! stories, while others explained that they dont see anything wrong hereits not like they couldve known. Besides that, one Redditor estimated that if they are first half-cousins, they share around 6 percent of DNA, which is not all that significant if they end up wanting to have kids. If anything, who cares, its their decision.

Yet others pointed out that this isnt all that uncommon, with one person saying that this happens around the world, not just in the South. In other countries, marrying cousins and other relatives was and still is culturally and religiously justified.

Image credits: u/PM_MeMyPassword

Whatever the case, you can check it all out in the original post here, and wed also love to hear what you think on the topic in the comment section below.

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Married Couple Takes DNA Test, Discovers They're First Cousins, Confront Family Who Kept It A Secret - Bored Panda

In the making of Adrian Lynes Deep Water, both of its stars had specific anxieties that they faced while developing their performances. For Ana de Armas, it was a concern about how audiences would receive her character the actor playing a selfish and vicious viper of a woman in the aftermath of her star-making, charismatic turn in Rian Johnsons Knives Out.

For Ben Affleck, however, the concern went deeper. According to the films director, Affleck expressed fear that his performance as the vulnerable and cuckolded Vic Van Allen in Deep Water was not something he felt was in his DNA. Lyne, however, knew differently.

I interviewed Adrian Lyne virtually last week prior to the release of Deep Water on Hulu, and during our conversation we spent time talking about his experience working with Ben Affleck and Ana de Armas both individually, and as an on-screen couple. The filmmaker told me that he expressly wanted a turn from Affleck that he had never seen before, and apparently it was a challenge that the star wasnt wholly sure he could overcome. Said Lyne,

I was very excited to see Ben Affleck in a different way. I didn't want him to be outgoing and sort of ebullient, which I'd seen before. In this movie, I wanted him to be sort of vulnerable, almost childlike. I wanted you to believe that he was obsessed with these snails. And so, a vulnerable man. And he would say at times during the movie, he would say, 'This isn't in my DNA,' but it was in his DNA because he did it for me!

In Deep Water, based on the novel of the same name by Patricia Highsmith, Ben Afflecks Vic is a wealthy, retired tech designer who is married to Ana de Armas Melinda Van Allen though they have an unconventional relationship. Wanting to maintain a stable family life for their daughter, Trixie (Grace Jenkins), he permits his wife to carry on extramarital affairs. While she is regularly off drinking and seducing young bachelors, he stays at home minding his snail farm.

It objectively is a very different kind of character and performance than we typically get to see from Ben Affleck, and Adrian Lyne shared how he helped evoke the turn from the actor. The filmmaker said that the chemistry tests with Affleck and Ana de Armas were not conducted in a cold, empty soundstage, but instead at his own home so that he could see the potential co-stars in a real domestic environment. Lyne explained,

What was interesting was that I tested them my house in Beverly Hills. They came around and it was good working there we were doing a test there, because I'd use the bathroom, I'd use the bedroom, I'd use the terrace or whatever, so it wasn't a sort of an antiseptic thing in a studio. And so it was very interesting just watching the chemistry between them, me the fly on the wall.

Continuing, Adrian Lyne recounted a specific moment from the test one that began with Ana de Armas interacting with Ben Affleck while he was off camera. But that didnt remain the case through the read, as Affleck found himself drawn in to join her in the scene:

There was a scene I remember, when she's sitting on the edge of the bed and she's putting lotion on her legs, and she's pissed off at him. And he's kind of wry and sort of dealing with it. And she's sort of semi-flirtatious. It's a nice mix between them. And so at one stage, after three or four takes... He was off camera, and he was intrigued with what she was doing, and he said, 'I'm going in.' Because he wanted to be part of working with her, for me to see that, you know? And so that was exciting, just seeing the start of the chemistry between them.

Should Deep Water ever get a home video release, one hopes that the recorded chemistry tests would be made available as a special feature. For now, audiences can enjoy their on-screen chemistry by watching the actual film, which is streaming exclusively on Hulu as of this past Friday (if you dont have a subscription its extremely easy to get one).

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Deep Water's Ben Affleck Feared His Performance Wasn't 'In His DNA,' But The Director Knew Otherwise - CinemaBlend

STONY BROOK, N.Y., March 23, 2022--(BUSINESS WIRE)--Applied DNA Sciences, Inc. (NASDAQ: APDN), a leader in cell-free, enzymatic DNA production, today announced that CEO Dr. James A. Hayward is invited to present at the 2022 Virtual Growth Conference presented by Maxim Group LLC and hosted by M-Vest, on March 28th - 30th from 9:00 a.m. - 5:00 p.m. EDT. Dr. Haywards presentation will be available on-demand for the duration of the conference via the sign-up link: Sign up here to access the presentation

During the virtual conference, investors will hear from executives from a wide range of sectors, including Biotech, Clean Energy, Electric Vehicles, Financial Services, Fintech & REITs, Gaming & Entertainment, Healthcare, Healthcare IT, Infrastructure, Shipping and Technology/Media/Telecom. The conference will feature company presentations, fireside chats, roundtable discussions, and live Q&A with CEOs moderated by Maxim Research Analysts.

This conference will be live on M-Vest. To attend, sign up to become an M-Vest member: Click Here to Reserve your seat

About Applied DNA Sciences

Applied DNA is commercializing LinearDNA, its proprietary, large-scale polymerase chain reaction ("PCR")-based manufacturing platform that allows for the large-scale cell-free production of specific DNA sequences.

The LinearDNA platform has utility in the nucleic acid-based in vitro diagnostics and preclinical nucleic acid-based drug development and manufacturing market. The platform is used to manufacture DNA for customers as components of in vitro diagnostic tests and for preclinical nucleic acid-based drug development in the fields of adoptive cell therapies (CAR T and TCR T therapies), DNA vaccines (anti-viral and cancer), RNA therapies, clustered regularly interspaced short palindromic repeats (CRISPR) based therapies, and gene therapies.

The LinearDNA platform also has non-biologic applications, such as supply chain security, anti-counterfeiting and anti-theft technology. Key end-markets include textiles, pharmaceuticals and nutraceuticals, and cannabis, among others.

Story continues

Leveraging its deep expertise in nucleic acid-based technologies, the Company has also established safeCircle, a high-turnkey solution for population-scale COVID-19 testing. safeCircle is designed to look for infection within defined populations or communities utilizing high throughput testing methodologies that increase testing efficiencies and provide for rapid turn-around-times.

Visit adnas.com for more information. Follow us on Twitter and LinkedIn. Join our mailing list.

The Company's common stock is listed on NASDAQ under the ticker symbol 'APDN,' and its publicly traded warrant is listed on OTC under the ticker symbol 'APPDW.'

Applied DNA is a member of the Russell Microcap Index.

View source version on businesswire.com: https://www.businesswire.com/news/home/20220323005721/en/

Contacts

Investor Relations: Sanjay M. Hurry, 917-733-5573, sanjay.hurry@adnas.com Web: http://www.adnas.com Twitter: @APDN

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Applied DNA to Participate in the 2022 Virtual Growth Conference Presented by Maxim Group LLC and Hosted by M-Vest on March 28th 30th from 9:00 a.m....

In today's DNA Special we analyse that news where there is a hidden lesson for others to learn.The world's number one female tennis player Ashleigh Barty from Australiahas announced retirement at the age of just 25 years.For the last 114 weeks, that is, for almost two years, she has remained the number one player in the world. She is also theAustralian Open title holder.

How big this success was, you can guess from the fact that in the last 44 years, no tennis player of Australia could win this Grand Slam. But Ashleigh Barty fulfilled this dream. At the time when she was at the peak of her career, she surprised everyone by suddenly announcing her retirement from the sport. So today a big question arises is that whether a person can get tired of his success?

Ashleigh Bartysays that she has fulfilled all the dreams she had for herself in the game of tennis and that is why she now wants to move away from tennis and fulfill her new dreams.It is not that Ashleigh Barty became successful overnight and then one day she suddenly decided to retire from this sport.

Read |Ashleigh Barty retirement: World no.1 breaks down, REVEALS why she's quitting tennis at age 25

When she first participated in an international tennis tournament, she was only 14 years old. The world first came to know about her when she won the Junior Wimbledon title in the year 2011. After this she also reached the doubles final of three Grand Slams.

In the year 2014, she became the number one female tennis player in the doubles category. She was then only 17 years old. And everyone felt that she could become a great tennis player. But at that time she suddenly announced to quit tennis and gave the reason behind it that she is suffering from mental stress due to her past successes.

To overcome this, he also decided to leave tennis and play cricket. And on the cricket field too, she won the match of life by defeating all the challenges. She played 10 matches in a cricket league named Big Bash and was associated with it for 17 months. However, after that she realised that she wanted to return to the tennis court.

And this comeback happened in the year 2016. After this she won the French Open in 2019, Wimbledon in 2021 and Australian Open Grand Slam in the same year. She managed to win 15 Singles and 12 Doubles category titles in her short career. During this tenure she won a prize money of 23.8 Million Dollar which is about Rs 180 crore as prize money.

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DNA Special: Here's why Ashleigh Barty bid goodbye to tennis at the age of 25 years - DNA India