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Detailed Cell Atlas of the Fallopian Tube Created – Technology Networks
Posted: March 27, 2022 at 10:27 pm
The fallopian tube is the site of fertilization, where once a month for the duration of a females post-pubescent, pre-menopausal life, an egg is moved from the ovary, ready for fertilization by a sperm cell.
A new study from Michigan Medicine researchers creates a detailed "atlas" of the various cell types and their gene activities within the highly specialized fallopian tube, paving the way for new research into infertility and other diseases affecting this organ, including some cancers.
Using tissue samples from four premenopausal women,Saher Sue Hammoud, Ph.D., andJun Li, Ph.D.from the Department of Human Genetics led a team at U-M to analyze almost 60,000 cells by single-cell RNA sequencing. They used the data to characterize the diversity of cells that make up the fallopian tube, including both the lining of the tube (the epithelium) and the deeper stromal layer, consisting of immune, blood, muscle, and other cells.
Hammoud and Li are joined byAriella Shikanov, Ph.D.,of the Department of Biomedical Engineering,Erica Marsh, M.D.,of the Department of Obstetrics and Gynecology, and team membersNicole Ulrich, M.D.,Yu-chi Shen, Ph.D., andQianyi Ma, Ph.D.Their project is part of the Human Cell Atlas Seed Networks, an international effort supported by the Chan-Zuckerberg Initiative to map all cells in the human body as a resource for better understanding health and disease.
Prior to their work, it was known that there are about four epithelial cell types in the fallopian tube, said Hammoud. We were able to reveal a deeper level of heterogeneity within these cells.
Specifically, they identified 10 epithelial cell subtypes, including four of the finger-like ciliated cells responsible for moving the egg through the fallopian tubes three sections before and after fertilization.
The cells within the fallopian tube are ever changing, replenishing themselves over time and varying in number depending on a womans age, hormones, menstrual cycle, and in the presence of disease. By comparing cells from women with healthy fallopian tubes to two samples from women with a fallopian tube disease known as hydrosalpinx (conventionally known as a blocked fallopian tube), the researchers were able to pinpoint which cells increased in number, and which changed characteristics, such as a high degree of inflammation.
Some of the cells are the cause of the disease state, and some others are the consequence; and now we know the patterns for individual cell types to figure out the molecular reasons for that pathology, commented Li.
The team also found that some of the cell subtypes they defined in the fallopian tube may function as precursor cells, those that can regenerate multiple cell types in response to normal tissue turnover, or for repairing a damage.
One of the most surprising findings of the study, says Hammoud, was the discovery of cells with markers for epithelial-mesenchymal transition, also known as EMT, a process not previously associated with the fallopian tube, through which a cell can, under certain circumstances, become cancerous.
Ovarian cancer, it turns out, may be a misnomer. The new study adds to accumulating evidence that the root of ovarian cancerthe fifth leading cause of cancer death in womenmay originate within the adjacent fallopian tube.
The EMT process seems to be tightly regulated in the pre-menopausal woman, she said. One possible connection to cancer is that when there is misregulation in this population of cells in some unfortunate individuals, they may develop ovarian cancer. With EMT cells in the fallopian tube, you do have the predisposition right there.
Additional insights came from the fallopian tube cells from women with hydrosalpinx, specifically, that the disease may lead to a type of scarring called fibrosis. The implication is that for women who dont want to have their tubes removed, you could think about treating them with anti-fibrotic drugs such as the ones used to treat lung fibrosis as a way to save their tubes during reproductive age, noted Hammoud.
Compared to past efforts, the study provides much more detailed information about cell types and functions in the tube for researchers interested in a host of questions about the normal female reproductive system. This really is a basecamp to launch future studies, says Li, including ones that look at the effects of age, the menstrual cycle, hormone therapy, and ancestral background on cellular diversity and disease pathology.
Reference:Ulrich ND, Shen Y chi, Ma Q, et al. Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified by scRNA-seq. Dev. Cell. 2021. doi: 10.1101/2021.09.16.460628
This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.
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Antibodies From COVID Infection Shield Kids for Up to 7 Months – HealthDay News
Posted: at 10:27 pm
TUESDAY, March 22, 2022 (HealthDay News) -- Antibodies from a COVID-19 infection linger in most children for up to seven months, even if they had no symptoms, a new study finds.
To come to that reassuring conclusion, researchers analyzed data from 218 children in Texas, ages 5 to 19, who were enrolled in an ongoing survey launched in October 2020 to track COVID-19 antibody status in children and adults over time.
Blood samples were collected from participants before vaccines became available and during the surges of the Delta and Omicron variants.
While 96% of children who were infected with COVID-19 still had antibodies at least six months later, 58% did not have infection-triggered antibodies at their third and final blood test.
The report, published March 18 in the journal Pediatrics, did not assess the impact of vaccination.
"This is the first study from the Texas CARES survey that includes data from all three time points in the survey," said corresponding author Sarah Messiah. She is a professor of epidemiology, human genetics and environmental sciences at the University of Texas Health Science Center at Houston.
"These findings are important because the information we collected from children infected with COVID-19 didn't differ at all by whether a child was asymptomatic, severity of symptoms, when they had the virus, were at a healthy weight or had obesity, or by gender," she added in a university news release. "It was the same for everyone."
To date, 14 million children in the United States have tested positive for the virus, and these findings help improve understanding of how it affects children, according to Messiah.
"Adult literature shows us that natural infection, plus the vaccine-induced protection, gives you the best defense against COVID-19. There has been a misunderstanding from some parents who think just because their child has had COVID-19, they are now protected and don't need to get the vaccine," Messiah said.
"While our study is encouraging in that some amount [of] natural antibodies last at least six months in children, we still don't know the absolute protection threshold," she added. "We have a great tool available to give children additional protection by getting their vaccine, so if your child is eligible, take advantage of it."
More information
For more on children and COVID-19, go to the American Academy of Pediatrics.
SOURCE: University of Texas Health Science Center at Houston, news release, March 18, 2022
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The Save Women’s Sports Act The Edgefield Advertiser – Edgefieldadvertiser
Posted: at 10:27 pm
All writers in Op Ed are here to inform and acknowledge issues of importance to our communities, however these writings represent the views and opinions of the authors and not necessarily of The Advertiser.
Robert Scott
Back in January,I wrote an OpEd about gender prejudice, and howone office holder expressed suchprejudice against transgender women in general and, specifically, prejudice regarding thethen-current Jeopardy champion,Amy Schneider.A discussion following that OpEdindicated thisprejudicewasbased ona generaldisbelief thatbeingtransgenderwas a medical and physical condition rather than a hoax or a so-called woke perception of something that was in fact not real.
We live in a complex world, and as our knowledge of human genetics and psychology increases,that complexity manifests itself ina number ofways. The validity of the transgender condition among some of our fellow human beings is one such complexity that is widely misunderstood,and thereforeit isnot yet accepted by many Americans. Our country has expanded its initial announced basis of liberty and freedom from All men are created equal as stated in the Declaration of Independence to include not just white men (as it wasgenerallyunderstood to mean in 1776) butallmenregardless of race, creed, or national origin;then, after generations of discussion,all men and women. We are struggling now to expand this to include all people, as evolving Science brings us into the knowledge that genderdoes not entirely fall into the binary categories we once thought. All people, we should now acknowledge, are not only created equal but are entitled to equal treatment as part of their inherent right to the pursuit of happiness.
SomeAmericans, including unfortunately some who represent us not only in Congress but in our State Legislature, continue to reject that notion. The latest manifestation of the gender prejudice inherent in such a rejection is a bill currently before the South Carolina Legislature entitled the Save Womens Sports Act.It should be voted down again (itfailed to be enacted last session), and here is why.The announced premise sounds reasonable enough: to require student athletes between grades 6 and 12 to compete in team sports based on the sex they were assigned at birth. Gender prejudice hides in the word assigned. The vast majority ofthefellow members ofourspecies are, indeed, fully male or fully female. But science is learning that for some small number, this is not the case. Some of them are inherently transgender havingimportantphysical and/or psychological traits appropriate to the gender opposite to that initial assignment, which really means assignment by our society based on an initialexternalassessment of just their plumbing.
If we recognize transgender youth as being who theyreallyare, even when they areonlyin grades 6 through 12, would that not compromise team sports, in particular by allowing some girls who were initially (and wrongly) assigned as males to play?Wouldnt suchchildrenhave an unfair advantage? The short answer isadvantage perhaps yes,but unfair advantageno not anymore than allowing exceptionally tall girls (or boys) toplay basketball despite being taller than anybody else, particularly anybody else in their school grade. If their pursuit of happiness includes trying out for a team and, if they are good enough, making that team, then we need to recognize and honor that. To do otherwise does not Save anybodys sports. It sets up a fundamental fairness issue thatis even more important to teach our children: in the United States of America, we assure to all people the unalienable rights to life, to liberty, and to the pursuit of happiness.Even transgender people.
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Ax-1 private mission to space station: Live updates – Space.com
Posted: at 10:21 pm
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In a press conference this evening, NASA officials said Axiom Space's private Ax-1 space mission is ready to launch to the International Space Station as early as April 3 at 1:13 p.m. EDT (1713 GMT), but only if NASA completes a critical fueling test of its new Space Launch System megarocket.
The Ax-1 mission, which will launch four private spaceflyers to the station on a 10-day trip, eight of them on the ISS, on a SpaceX rocket. SpaceX uses Pad 39A at NASA's Kennedy Space Center in Florida. NASA's Artemis 1 Space Launch System megarocket is standing atop the nearby Pad39B for a vital "wet dress rehearsal" which is scheduled for April 1 to April 3.
It is possible that NASA will complete the Artemis 1 fueling test early enough on April 3 for Ax-1 to fly. If not, the private mission's launch window extends through at least April 7, NASA said.
NASA, SpaceX and Axiom Space have completed a day-long flight readiness review meeting today, March 25, for the planned Axiom Mission (Ax-1) to the International Space Station set to launch no earlier than April 3, 2022.
The mission, which will launch on a SpaceX Falcon 9 rocket and Crew Dragon spacecraft, will carry four private astronauts to the space station for the first time. It is the first all-private mission to the station in its over 20-year history.
Ax-1 will launch former NASA astronaut Michael Lpez-Alegra and paying passengers Larry Connor, Mark Pathy and Eytan Stibbe. Lpez-Alegra will command the flight. The space travelers will spend 10 days in space and plan to perform a series of science experiments and studies on the space station while also enjoying the commercial spaceflight experience.
"During the 10-day mission, the crew will spend eight days on the International Space Station conducting scientific research, outreach, and commercial activities," NASA officials said in a statement.
NASA will hold a press teleconference tonight at 6 p.m. EDT (2200 GMT) to discuss plans for the Ax-1 mission. You can listen in on the mission live here.
Speaking during tonight's press conference will be:
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This Week @NASA: Landing Artemis Astronauts on the Moon, Space Station Upgrade Work – SciTechDaily
Posted: at 10:21 pm
Illustration of an Artemis astronaut on the Moon. Credit: NASA
Upgrade work continues outside the space station
An updated strategy for landing Artemis astronauts on the Moon
And unsealing pieces of the past a few of the stories to tell you about This Week at NASA!
On March 23, the crew onboard the International Space Station conducted the second spacewalk this month to continue upgrades to the orbiting laboratory. During the outing, NASA astronaut Raja Chari and European Space Agency astronaut Matthias Maurer worked to install new thermal system and electronics components on the stations U.S. segment. They also worked to install a power and data cable on the Columbus modules Bartolomeo science platform, replace an external camera on the stations truss, and conduct other upgrades to station hardware.
Updated Strategy for Landing Artemis Astronauts on the Moon
Also on March 23, we announced plans to create additional opportunities for commercial companies to develop an astronaut Moon lander that can transport humans between our lunar orbiting space station known as Gateway and the lunar surface, for missions beyond Artemis III, which will be the first mission to land astronauts on the Moon in more than 50 years. The announcement is part of a strategy by the agency to pursue two parallel paths for continuing lunar lander development and demonstration, one that calls for additional work under an existing contract with commercial partner, SpaceX, and another open to all other U.S. companies. This effort is meant to maximize NASAs support for competition and provides redundancy in services to help ensure NASAs ability to transport astronauts to the lunar surface.
One of the last unopened Apollo-era lunar samples collected 50 years ago during Apollo 17 has been opened at our Johnson Space Center in Houston. Sample 73001 had been kept vacuum sealed and in pristine condition in anticipation of the day that scientists equipped with advanced technology could examine it. The Apollo Next Generation Sample Analysis Program is studying the sample and others like it, as we prepare to send astronauts back to the Moon for more samples on upcoming Artemis missions.
On March 21, the number of confirmed exoplanets, or planets outside of our solar system, ticked past the 5,000 mark. The milestone was reached when the latest batch of 65 exoplanets was added to the NASA Exoplanet Archive. This stream of exoplanet discoveries that began 30 years ago, includes contributions from NASAs TESS, Kepler, and Spitzer space telescopes, with more discoveries possible in the future from our James Webb and Nancy Grace Roman space telescopes.
On March 22, the newest U.S.-European sea level satellite, named Sentinel-6 Michael Freilich, became the official reference satellite for global sea level measurements. This means that sea surface height data collected by other satellites will be compared to the information produced by Sentinel-6 Michael Freilich to ensure accuracy. The satellite, which is named after NASAs former Earth Science Division Director, the late Dr. Michael Freilich, was launched in November 2020.
Thats whats up this week @NASA
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From Ukrainians to astronauts on the ISS, Jos Andrs is feeding anyone in needand well – Fast Company
Posted: at 10:21 pm
There will always be somebody ready to do whatever it takes to feed their fellow citizens, says Spanish chef Jos Andrs. Thats been his mission since 2010, when he launched his nonprofit organization World Central Kitchen (WCK) to cook hot meals for victims of the Haitian earthquake. He later brought the organization to storm-ravaged Houston and Puerto Rico. Over the past couple of years, WCK also served more than 40 million meals to people whose lives and livelihoods were affected by the pandemic.
[Photo: courtesy ThinkFoodGroup]One day after the Russian invasion of Ukraine, WCK mobilized to address the war, setting up in eight locations along the Polish border with Ukraine. Within weeks, the nonprofit had established partnerships with restaurants and food trucks to distribute meals to people at border crossings, shelters, train stations, and other locations across the region, including Ukraine, Poland, Hungary, Moldova, and Romania. Its also focused on getting bulk produce and supplies to partner restaurants inside Ukraine to alleviate strained supply chains. The organization is now serving some 180,000 daily meals to people displaced by the war. It has also mobilized restaurants and chefs outside the region to support its efforts in Ukraine by hosting #ChefsForUkraine fundraising dinners.
At the same time, Andrs has been working to bring his food into space. In early April, two dishes designed by his company, ThinkFoodGroup, will launch with a multinational crew headed to the International Space Station, on a mission put together by commercial space company Axiom Space. Andrs, who got involved through his friendship with veteran astronaut Michael Lpez-Alegra, commander for the upcoming mission, says that he has long dreamed of making meals for astronautsand even going to space himself.
Fast Company talked with him about working in a war zone, designing meals for astronauts, and the power of paella.
Fast Company: How is your work in Ukraine different from what youve done in other crisis zones?
Jos Andrs: Were a young NGO. Weve never been in an active war zone. Weve been in situations of instability, like Venezuela or Haiti, but this is a true war scenario. We began working in the countries surrounding Ukraine, except for Russia. We began in Poland, but very quickly we sent teams to Hungary and Romania. I think were doing 180,000 meals a day, mainly because more and more refugees keep leaving Ukraine. We see that the need inside [Ukraine also] keeps increasing.
Everybody talks about the three million refugees, but nobody talks about the other two to three million, if not more, that are displaced inside Ukraine. So there are at least six million people whose lives have been destroyed. Plus the other millions who are in cities where theres bombing and shelling. So we are talking about probably 10-, 12-, 13 million people whose lives are not the same anymore. This is a major event.
FC: Whats the security situation for an NGO like World Central Kitchen?
JA: Obviously, there is a lot of security advice. Sometimes it sounds more [like something] from a James Bond movie than real life, but you take them seriously. Some foreign Russian assets try to distort facts to create mayhem, but you still have to take all security advice seriously. Because of the security risk, we have to send food to different cities using different protocols and systems. Were figuring out how to navigate checkpoints: Its quicker to get through when security recognizes that you are feeding people.
FC: How are you actually getting food to people?
JA: Ive found that there will always be somebody ready to do whatever it takes to feed their fellow citizens. Weve been supporting people [in local food businesses] with money, with assets, with equipment, and with food. We are supporting bakeries and distributors. We have been serving venison that people have huntedand lots of soups because its so cold and people need warmth.
[Photo: courtesy ThinkFoodGroup]FC: Youre also trying to feed people in space. How did your collaboration with Axiom Space come about?
JA: Ive been talking to NASA now for a long time. I had NASA people come to my main office meet with me and my team a few times in the last 10 or 12 years. At Axiom, we ended up working with a lot of people from the NASA team we used to talk to. I am friends with [astronaut] Michael Lpez-Alegrahe is also Spanishwho is leading the group to the [International Space Station] with Axiom. When I created WCK, I always said, We send doctors and nurses to help the sick, so why dont we send cooks to feed people who need it? I always wanted to push those boundaries. The truth is that we will be on Mars or Jupiter or whatever one day. We have all this technology to go to another planet but we dont have the will on earth to make our planet better.
FC: How did you decide what dishes to serve on the ISS?
I mean: Spanish chef, Spanish astronaut. For me, we had to do one of the most iconic Spanish dishes, paella. Its a rice dishwe made one with chicken and mushrooms and there are rice dishes around the world. In India you have biryani, in Brazil and China you have rice dishes, too. So, it felt kind of international. We also made secreto de cerdo con pisto, an ibrico pork dish with tomatoes, onions, eggplant, and peppers, because I wanted to showcase another Spanish dish. But I now realize that one of the astronauts cant eat pork! The most important one to me is the paella.
[Photo: courtesy ThinkFoodGroup]FC: What were the R&D challenges of designing a dish that can travel into space?
JA: Well, first of all, we did this all in the middle of a pandemic. A lot of it was less science and more trial and error. I had my team members helping me with this one, and they tested over 100 iterations of the paella. We had to create a meal where all of the ingredients could be put in an opaque bag, and put on a metal shelf to get warmed up for half an hour before being consumed. We had to figure out how liquid would reduce in the bag to make sure the paella wasnt too soft or too hard and the moisture level was perfect. We had to figure out the quantities of each raw ingredient, how and how they would cook under pressure. We tested it in Houston and then in our offices and in our homes trying to recreate the conditions.
FC: Theres now a rift between the ISSs two main partners, the United States and Russia. Russias space chief even raised the idea of Russia leading the ISS into an uncontrolled deorbit in a series of tweets criticizing U.S. sanctions against Russia. Has this affected your work?
JA: This meal will be shared by all Axiom Mission 1 astronauts. Paella is a communal dish, and everybody in the Ax-1 crew will share it. I dont know that this is the beginning of the peace process, but its good for people to eat together and see each other across a table.
FC: Do you plan on making more dishes to be consumed in space down the line?
JA: I hope so. Critics will say that with so much hunger on this planet, why spend money to go to space? I say we can do both. More and more people are going to be going to space. Its important to have good people working on these things.
FC: Do you plan on going to space?
JA: Youre going to laugh at me, but Ive been getting into shape over the last two or three years. Somebody told me everybody has a 1% chance of going up there. I mean, Ive been down in a submarine into the deep sea. Im a cook who barely graduated [from high school]. Anything is possible. I started cooking rice dishes with my father when I was a kid, and now I am making the same dish for a crew going to the International Space Station.
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NASA funds University of Utah Health project on biological impacts of space travel – Salt Lake Tribune
Posted: at 10:21 pm
(NASA/Roscosmos via AP) In this photo provided by NASA/Roscosmos, the International Space Station continues its orbit around the Earth as seen from a Soyuz spacecraft departing with NASA astronauts Andrew Feustel and Ricky Arnold and Roscosmos cosmonaut Oleg Artemyev, who had spent 197 days in space. The University of Utah Health received funding to study how space travel affects the health of astronauts.
| March 26, 2022, 1:00 p.m.
This story is part of The Salt Lake Tribunes ongoing commitment to identify solutions to Utahs biggest challenges through the work of the Innovation Lab.
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Dr. Hans Schwertz always dreamt of the stars. As a kid back home in Germany, he found himself gazing at the sky after reading a book about space. One of his prized possessions growing up was a print of the picture Earthrise snapped by Apollo 8 astronaut Bill Anders.
I always told my kids I would love to stand on the moon and see the earth rise, Schwertz, an adjunct professor of family and preventive medicine at the University of Utah Health who practices medicine in Montana said. That would be so cool.
Schwertz realized hed probably never fly to the moon, so he searched for a different way to get a taste of space. As an occupational doctor, he started researching the impacts space travel has on astronauts.
Schwertz and Dr. Matthew Rondina, a professor of internal medicine and pathology at the U., pitched a grant proposal to NASA that would examine how astronauts physically adapt and acclimate to space by looking at bone marrow cells and blood platelets during space travel. Such cells help protect against infectious disease and inflammation and can weaken outside of Earths environment.
(Hans Schwertz) Dr. Hans Schwertz, adjunct professor of family and preventive medicine at the University of Utah Health, working on a research project examining how astronauts' cells react and adapt to space travel. The research is one of ten biology projects funded by NASA in 2021.
NASA passed on their proposal twice, but their third attempt ended in success. Schwertz and Rondina were awarded one of ten biology grants offered by NASA in 2021, U. Health announced Wednesday.
I was in actual tears, as cheesy as that sounds, Schwartz said when he found out NASA accepted their proposal. I guess the third time was the lucky charm.
Its been nearly 60 years since America began space exploration. Research indicates astronauts experience a stressful environment in space and are exposed to cosmic radiation, confinement, lower gravitational pulls, different kinds of bacteria, lowered immunity and a loss of muscle and bone mass. These conditions have been linked to an increased risk of hemorrhages, blood clots and slower recovery times.
Schwertz says as NASA plans to explore Mars or establish a space station on the moon, the U. Healths research could prove invaluable, especially since the long-term effects of space travel on astronauts remain largely unknown.
We are talking about long time spans [in space] and about areas that are not protected by the Earths magnetic field, he noted. So cosmic radiation and stuff like that will be much more pronounced and that needs to be explored, and there needs to be research on what risks we put on those astronauts.
Through a voluntary process, blood samples of astronauts will be drawn before they go to space, during space travel, and examined in real-time, then researchers will compare the two culture samples. Once the astronauts return to Earth, another blood sample will be taken. The team of five will also simulate cosmic radiation in a lab to see how the cells react to exposure.
(Hans Schwertz) Dr. Hans Schwertz, adjunct professor of family and preventive medicine at the University of Utah Health, working on a research project examining how astronauts' cells react and adapt to space travel. The research is one of ten biology projects funded by NASA in 2021. This photo was taken prior to the COVID-19 pandemic when masks inside U. Health facilities were not mandated.
Additionally, Rondina highlights this research could advance medicine on Earth by broadening the understanding of how bone marrow cells and platelets contribute to inflammation, immunity and wound healing.
This knowledge could potentially lead to new treatments for a host of autoimmune diseases and other disorders, Rondina said in the U. Health statement.
If everything goes as planned, Schwertz and Rondinas research could board the International Space Station and blast off into space within the next year.
I cannot tell you how much I will enjoy that moment when I stand at the Kennedy Space Center with my family, kids in hand and watch the experiment really fly, Schwertz said proudly. Its going to be so rewarding to show them this is possible.
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Humans could live up to 150 years will you make it beyond a century?… – The US Sun
Posted: at 10:18 pm
HUMANS could live until the ripe old age of 150 years according to recent research and scientists are racing to work out how.
Harvard geniuses, biohackers and internet billionaires are all looking for ways that humans can crack the code on aging.
3
WaitButWhy blogger Tim Urban writes the human body seems programmed to shut itself down somewhere around the century mark, if it hasnt already".
And Urban is right! There are no verified cases of a person living to be older than 122, though the oldest living person is on their way at age 119.
Researchers at GERO.AI concluded the "absolute limit" of the human lifespan to be between 100 and 150 - they came to this conclusion by analyzing 70,000 participants up to age 85 based on their ability to fight disease, risk of heart conditions and cognitive impairment.
The Conversation reported that not a single participant showed the biological resiliency to live to 150 - but notes the study is limited by today's medical standards.
Will improvements in medicine, environment and technology to drastically lengthen the average lifespan and make 150 a reality?
The human body is made up of about 30trillion cells. Cells are constantly dying and being replaced by replicants.
Within the cell body there are chromosomes - these are DNA strands with the code written for humans within them.
At the end of a DNA strand is a microscopic bundle of non-crucial DNA, so that none of the important stuff gets snipped off when the cell divides.
A cell can divide itself about 50 times before it's lost its ability to replicate.
As more and more cells become ineffective and die, the signs of aging start to show in gray hair, weaker bones and vision loss.
Some theorize this process can be stopped or reversed.
Researchers at Harvards Sinclair Lab write: If DNA is the digital information on a compact disc, then aging is due to scratches. We are searching for the polish.
Dr David Sinclair, the founder of the lab and one of the foremost scientists working on anti-aging technologies, led an experiment that restored the vision of elderly mice.
The team injected the mice with a serum of genes that affected the DNA of the cells in the eye.
Our study demonstrates that its possible to safely reverse the age of complex tissues such as the retina and restore its youthful biological function,Sinclair said.
Some people are fighting age not with tests on mice, but on themselves.
Dave Asprey is an author and entrepreneur who predicts hell live to 180 based on his method of biohacking.
Asprey, 49, has invested over $2million in technologies he believes will alter his biology including stem cell injections and cryotherapy chambers.
Asprey was quoted as saying The things I am working to pioneer, some of them are expensive, some of them are free like fasting. This will be like cell phones, everyone has cell phones - everyone will have anti-ageing. Change can happen rapidly in society.
But even visionaries like Elon Musk are wary of immortality, and the billionaire theorizes it could lead to an elderly population with stagnated ideas.
Although the body shuts down, there is a line of thinking that if just our consciousnesses could be preserved, maybe humans could live longer not just 150 years but forever.
Our capacity to get the brain to interface with a computer is currently low weve applied chips that communicate with just a few hundred of the 86billion neurons but a Russian billionaire is aiming to duplicate our entire consciousness and upload it onto a computer where it can live forever as a robot or hologram.
In the 2045 Initiatives manifesto, Dmitry Itskov writes People will make independent decisions about the extension of their lives and the possibilities for personal development in a new body after the resources of the biological body have been exhausted.
Of course, if this idea were to be achieved, you would have to exit your current body in favor of your "new body".
Is that, on some level, a form of death? Do you restart at age zero once your consciousness has been duplicated? Do you age at all while living inside a computer?
These are biomedical ethics questions that are sure to be debated as the search for a prolonged lifespan carries on both in the hospital and the computer lab.
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Humans could live up to 150 years will you make it beyond a century?... - The US Sun
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The Brian Jonestown Massacre reveal new album is on the way | Gigwise – Gigwise
Posted: at 10:16 pm
The Brian Jonestown Massacre are returning with their 19th studio album Fire Doesnt Grow On Trees, out 24 June on Anton Newcombes label A Recordings. Theyve also shared a new single, The Real, to celebrate the news. The announcement comes on the 30th anniversary of their very first single.
The Real is five minutes of great rock n roll, tinged with psychedelic elements that we can expect to hear throughout the album. Its a lyrically heavy track, which frontman Anton Newcombe describes as being a call to arms for the difficult times that we have ahead:
I'm trying to give comfort and support to the listener in a very matter of fact kind of way, it's a call to arms, the beast can be this overwhelming darkness, the dragon, dickheads telling you that you need to be trans-human, modified to be whole and survive A.I. it's absolute madness... we are in for a tough ride, have no illusions.
Fire Doesnt Grow On Trees Tracklist:
Fire Doesnt Grow On Trees arrives 24 June on A Recordings.
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MICHAEL REAGAN: Welcome home to America the angry – The Albany Herald
Posted: at 10:15 pm
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