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Category Archives: Transhuman News

DNA tests solve 23-year-old Fla. murder case

Posted: February 25, 2014 at 8:45 pm

Authorities in Florida say they have solved the 23-year-old mystery of a woman's strangulation death in Broward County and linked the crime to a convicted killer who was executed in 2011 for a triple murder.

DNA evidence identified Oba Chandler as the suspect in the murder of Ivelisse Berrios-Beguerisse, who was found dead in a quiet Coral Springs neighborhood on Nov. 27, 1990, police said Monday.

Dan Cucchi, a cold case detective with the Coral Springs Police Department, told the Sun-Sentinel that the original investigators on the case had gathered and processed DNA samples without much success because the technology was less sophisticated and a database with criminals' DNA did not exist at the time.

"Mr. Chandler, when he was convicted in 1994, that's when his DNA profile would have been entered into the national database, so it was in there in that time period," Cucchi told the newspaper. "It's just that we didn't have a profile from our victim's rape kit at that time."

Chandler was convicted in the rape, strangulation and killing of a St. Petersburg woman and her two daughters. He was executed by lethal injection in 2011 at the age of 65, the Sun-Sentinel reported.

Berrios-Beguerisse was last seen leaving work at the Sawgrass Mills mall. Her husband went to the mall and called police after finding her 1985 Ford Tempo with two slashed tires, the report said.

Her body was found three hours later with ligature marks on both wrists and ankles and brown packing tape stuck in her hair, Cucchi said.

"Back in 1990, rape kits and the DNA collection process were not the same but now it's way more advanced," Cucchi told the newspaper. "You can actually take a smaller sample and through the new technology they can develop potential profiles and suspect DNA, where in the past they could not."

Cucchi andfellow detective Brian Koenig were assigned the cold case last August and asked the Broward Sheriff's Office Crime Lab to perform tests on the DNA samples again.

If Chandler were still alive, he would be charged with the strangulation death of Berrios-Beguerisse, police told the Sun-Sentinel.

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DNA tests solve 23-year-old Fla. murder case

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Better DNA technology helps Florida police solve 23-year-old murder

Posted: at 8:45 pm

CORAL SPRINGTS, Fla., Feb. 25 (UPI) -- The murder of a 20-year-old south Florida woman 23 years ago has finally been solved because of improvements in DNA technology and procedures, police say.

However, the suspected killer was executed in 2011 for a 1989 triple murder, the South Florida Sun-Sentinel reported Tuesday.

Ivelisse Berrios-Beguerisse was found naked and asphyxiated in November 1990 in a Coral Springs neighborhood three hours after she left work at a Broward County mall. Investigators gathered genetic evidence, said cold-case investigator Dan Cucchi, but the technology at the time was less sophisticated than today. Additionally, there was no database of DNA from convicted criminals with which to compare it.

Cucchi and his partner, Brian Koenig, were assigned the case in August. They asked for DNA evidence collected more than two decades to be retested.

The DNA matched Oba Chandler, convicted in 1994 in the rape, strangulation and killing of Joan Rogers and her two teenage daughters in St. Petersburg.

He was executed by lethal injection three years ago.

Chandler's DNA was collected when he was convicted, four years after the death of Berrios-Beguerisse, but "it's just that we didn't have a profile from our victim's rape kit at that time," Cucchi said.

In the interim, forensic technology also changed.

"Back in 1990, rape kits and the DNA collection process were not the same but now it's way more advanced," the detective said. "You can actually take a smaller sample and through the new technology they can develop potential profiles and suspect DNA, where in the past they could not."

Koenig said he and Cucchi are also examining other cold cases that might have similar evidence.

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Better DNA technology helps Florida police solve 23-year-old murder

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DNA expert takes the stand in triple murder trial

Posted: at 8:45 pm

CHARLOTTE, NC (WBTV) -

A DNA analyst took the stand in the trial of a man police said killed three people in Mecklenburg County.

Justin Hurd is accused of killing Kevin Young, Kinshasa Wagstaff and Jasmine Hines in 2008. Detectives said Hurd and another man tried to cover up the triple murder by burning down the home where the victims lived.

On Monday a jailhouse snitch testified Hurd confessed.Justin Hurd has been in jail since 2009 when he was arrested in Ohio and accused of the triple murder In North Carolina.Two jailhouse mates testified.The second one was still on the stand Tuesday as defense lawyers attacked his credibility.

"You started out your interaction with Mr. Hurd by saying I'm facing life in jail but nonetheless he picked you as a confident," asked defense lawyer Alan Bowman of Louis Misenheimer.

"No we started out playing basketball together," said Misenheimer.

Misenheimer also said that he was hoping to have his sentence reduced in connection with his testimony that Hurd told him he was involved in the killings.

Prosecutors transitioned the focus back to hard evidence and prepared to introduce DNA collected by the lead investigator, detective Phillip Rainwater, who went to Ohio and described to the jury the man he met.

"The second subject from the left side at that table wearing black jacket, striped silver black tie, white shirt, beard, glasses," said Rainwater pointing at Justin Hurd.

For a long time the defense and prosecution argued about whether Rainwater could tell the jury Nate Sanders, the man prosecutors said worked with Hurd to kill the three people, was dead and was murdered. Defense lawyers said if the information is openly shared they want the jury to be aware another man is accused of the killing and indicted.

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DNA expert takes the stand in triple murder trial

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Making baby with DNA of 3 people: FDA weighs new technique

Posted: at 8:45 pm

Originally published February 24, 2014 at 12:43 PM | Page modified February 25, 2014 at 5:43 AM

Federal health regulators will consider this week whether to green light a provocative new fertilization technique that could eventually create babies from the DNA of three people, with the goal of preventing mothers from passing on debilitating genetic diseases to their children.

The Food and Drug Administration has framed its two-day meeting as a "scientific, technologic and clinical" discussion about how to test the approach in humans. But the technique itself raises a number of ethical questions, including whether the government should sanction the creation of genetically modified humans.

The FDA panel will hear from several prominent critics who oppose any human testing of the approach, arguing that it could be a slippery slope toward "designer babies," -- in which parents customize traits like eye color, height and intelligence.

But the field's leading U.S. researcher will be on hand to explain and defend his work, which he describes as "gene correction," rather than "gene modification."

"We want to replace these mutated genes, which by nature have become pathogenic to humans," says Dr. Shoukhrat Mitalipov, who will present on Tuesday. "We're reversing them back to normal, so I don't understand why you would be opposing that."

The FDA meeting was prompted by Mitalipov's research at Oregon Health & Science University in Portland, where he and his staff have produced five healthy monkeys using the DNA-replacement technique. He is seeking FDA approval to begin testing in a handful of women who carry defective genes that can lead to devastating diseases in children, including blindness, organ failure and epilepsy.

An estimated 1 in 5,000 U.S. children inherit such conditions because of defective DNA in their mitochondria, small energy-producing organs found in the cell. Unlike most DNA -- located in the nucleus of the cell -- mitochondrial DNA is passed along only by the mother, not the father.

The experimental technique, if approved for use, would allow a woman to give birth to a baby who inherits her normal nucleus DNA but not her defective mitochondrial DNA.

To accomplish this, researchers would remove the nucleus DNA from a healthy female donor's eggs and replace it with the nucleus DNA of the prospective mother. After fertilization, the resulting child would inherit the mother's nucleus DNA -- which contains most inherited traits like eye color and height -- but the donor's healthy mitochondrial DNA.

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Making baby with DNA of 3 people: FDA weighs new technique

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Genome Sequencing : Anu Acharya at TEDxPune – Video

Posted: at 8:44 pm


Genome Sequencing : Anu Acharya at TEDxPune
Ms. Anu Acharya is the CEO of Mapmygenome India Limited, an Indian genomics company providing a range of prognostics, diagnostics, and brain wellness solutions. She is the Founder of Ocimum...

By: TEDxTalks

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Genome Sequencing : Anu Acharya at TEDxPune - Video

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CSHL Professor W. Richard McCombie speaks at the CSHLA Genome Education Presentation – Video

Posted: at 8:44 pm


CSHL Professor W. Richard McCombie speaks at the CSHLA Genome Education Presentation
Professor McCombie gives a lecture to the CSHL Association. CSHL at the Crossroads of Genome Science. January 23, 2014.

By: ColdSpringHarborLab

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CSHL Professor W. Richard McCombie speaks at the CSHLA Genome Education Presentation - Video

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GSK Extends Offer for Human Genome Again – Video

Posted: at 8:44 pm


GSK Extends Offer for Human Genome Again
GlaxoSmithKline is relentless when it comes to this acquisition. The company again extended its $2.6 billion offer to buy Human Genome Sciences till July 20t...

By: FinancialOnlineNET

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GSK Extends Offer for Human Genome Again - Video

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Neanderthal Genes Found in Modern Humans New Studies Confirmed – Video

Posted: at 8:44 pm


Neanderthal Genes Found in Modern Humans New Studies Confirmed
Neanderthal genes lurk among us. Small traces of Neanderthal DNA have been confirmed in the areas of the genome that affect skin and hair of modern humans, a...

By: Idle times

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Neanderthal Genes Found in Modern Humans New Studies Confirmed - Video

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New tumor suppressor gene will facilitate detection of people susceptible to skin cancer

Posted: at 8:44 pm

The human genome contains approximately 20,000 protein coding genes which are responsible for the formation, development and functioning of the human body. A similar number of genes exists in the mouse genome. In this pool only some genes -- called tumor suppressors -- can initiate the production of proteins having anti-cancer properties. Polish-Australian team of researchers from the Nencki Institute of Experimental Biology of the Polish Academy of Sciences in Warsaw .and Monash University Central Clinical School in Melbourne showed that one of the genes, known as GRHL1, displays anti-cancer effects which is protective against skin cancer of non-melanoma type.

"In humans, we know more than 700 tumor suppressor genes, but only a few of them prevent the development of skin cancer. We have identified yet another tumor suppressor gene, whose damage certainly increases the risk of skin cancer, at least in a mouse model," says Dr. Tomasz Wilanowski from the Nencki Institute.

Cancer is currently one of the deadliest and most common diseases. According to statistical data from the World Health Organization, annually more than 8 million people die of cancer worldwide. Therefore understanding the causes of this disease and development of effective methods of prevention and therapy of cancer are of great social importance.

In 1998, Dr. Wilanowski identified, cloned and described a new human gene. GRHL1 (Grainyhead-like 1) proved to be a factor co-responsible for the formation of the largest human organ: the skin. This allowed the Polish-Australian research team to carry out experiments on the influence of this gene on the incidence of skin cancer.

"The tests that we conducted recently in our laboratory, leave no doubt. In the control mice, severe skin cancers developed in 7% of the population. In knockout mice, that is, in mice lacking the functional GRHL1 gene, such tumors appeared in as many as 33% of cases," says PhD student Michal Mlacki of the Nencki Institute, lead author of the paper that was just published in a well-known scientific journal PLOS ONE.

Researchers from the Nencki Institute emphasize that these numbers cannot be automatically applied to the human population. "Although mouse and human are very similar in terms of genetics and physiology, they are still different organisms. Mice are only research models of human disorders and facilitate better understanding of disease processes," says Michal Mlacki.

"Today we cannot yet unequivocally answer the question whether people with a defective GRHL1 gene will be five times more likely to develop non-melanoma skin cancer, as it happens in mice, or whether the risk of this disease will increase fourfold, or sixfold. Studies on the determination of the scale of the increased risk in human population have only just begun," notes Dr. Wilanowski.

Finding of a new tumor suppressor gene is the first step towards the development of tests to detect defective GRHL1 gene in children and adults. In the future, people aware of their genetic defect could take preventive measures to reduce the risk of skin cancer, for example, by avoiding tanning salons, suitably dressing on a sunny day or using creams effectively blocking ultraviolet radiation.

"Gene itself is only the vehicle of information. It is the encoded protein that is responsible for anti-cancer effect of the GRHL1 gene. Now that we know the functions of this protein, we would like to find a way to stimulate its activity in the human body. And this is the way not only to prevention, but also to future drugs that can be administered to patients," says Dr. Wilanowski.

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New tumor suppressor gene will facilitate detection of people susceptible to skin cancer

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Feet, fork and fingers: clue to health, longevity, national medical expert says

Posted: at 8:44 pm

COLLEGE STATION If a new medication came on the market to help one lose weight, increase exercise, stop smoking and prevent heart disease, cancer, stroke, respiratory illness and diabetes, people would flock to physicians for a prescription and buy stock in the company, one expert believes.

But thats not likely, according to Dr. David Katz, a physician and director of the Yale Prevention Research Center, who spoke at Texas A&M University today.

Yet, the knowledge already exists to prevent those ailments and few are taking advantage, Katz told about 200 people at the Produce for Health seminar conducted by Texas A&Ms Vegetable and Fruit Improvement Center.

Its about lifestyle factors and a plant-based diet, Katz said. Weve seen it in repetitive scientific studies.

The Vegetable and Fruit Improvement Center hosted Katz as part of the 20th anniversary of its collaborations among plant production scientists, medical researchers, farmers and food industry experts. The center was created in 1993 as researchers worldwide began to realize the connection between food consumption, food production and human health, according to Dr. Bhimu Patil, director.

Weve known for a long time the top five causes of premature death in humans heart disease, cancer, stroke, respiratory ailments and diabetes, Katz said. What changed in 1993 was a scientific study that encouraged researchers to realize that these are effects not causes. Thats when we began to look for the causes and found that virtually all premature deaths are attributable to diet, exercise and tobacco.

He calls them the feet, fork and fingers: failure to exercise, improper eating and smoking.

In a study that compared people who eat poorly, have out-of-control weight and smoke to people who eat well, have their weight in control and do not smoke, we learned that reversing any one of those would increase ones lifespan by 50 percent. Reversing all three would increase lifespan by 80 percent, Katz said.

The U.S. fight over health care, he added, was about money not health.

The whole thing (mandatory health care) is moot if we dont solve this problem with obesity and the projection about what it will do to our future, Katz said, pointing out that obesity in U.S. children may be linked to the recent 35 percent increase in strokes for children 5-14 years old.

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Feet, fork and fingers: clue to health, longevity, national medical expert says

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