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Category Archives: Transhuman News

Gene may predict if further cancer treatments are needed

Posted: March 29, 2014 at 12:42 am

UT Southwestern Medical Center researchers are developing a new predictive tool that could help patients with breast cancer and certain lung cancers decide whether follow-up treatments are likely to help.

Dr. Jerry Shay, Vice Chairman and Professor of Cell Biology at UT Southwestern, led a three-year study on the effects of irradiation in a lung cancer-susceptible mouse model. When his team looked at gene expression changes in the mice, then applied them to humans with early stage cancer, the results revealed a breakdown of which patients have a high or low chance of survival.

The findings, published online in Clinical Cancer Research, offer insight into helping patients assess treatment risk. Radiation therapy and chemotherapy that can destroy tumors also can damage surrounding healthy tissue. So with an appropriate test, patients could avoid getting additional radiation or chemotherapy treatment they may not need, Dr. Shay said.

"This finding could be relevant to the many thousands of individuals affected by these cancers and could prevent unnecessary therapy," said Dr. Shay, Associate Director for Education and Training for the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern. "We're trying to find better prognostic indicators of outcomes so that only patients who will benefit from additional therapy receive it."

Dr. Shay's study closely monitored lung cancer development in mice after irradiation. His group found some types of irradiation resulted in an increase in invasive, more malignant tumors. He examined the gene expression changes in mice well before some of them developed advanced cancers. The genes in the mouse that correlated with poor outcomes were then matched with human genes. When Dr. Shay's team compared the predictive signatures from the mice with more than 700 human cancer patient signatures, the overall survivability of the patients correlated with his predictive signature in the mice. Thus, the classifier that predicted invasive cancer in mice also predicted poor outcomes in humans.

His study looked at adenocarcinoma, a type of lung cancer in the air sacks that afflicts both smokers and non-smokers. The findings also predicted overall survival in patients with early-stage breast cancer and thus offer the same helpful information to breast cancer patients; however the genes were not predictive of another type of lung cancer, called squamous cell carcinoma. Other types of cancers have yet to be tested.

The American Cancer Society estimates the risk of developing lung cancer to be 1 in 13 for men and 1 in 16 for women, including both smokers and non-smokers. Lung cancer is the second most common cancer in both men and women, accounting for about 13 percent of all new cancers, and about 27 percent of cancer deaths. The American Cancer Society estimates more than 224,210 new cases of lung cancer and nearly 160,000 deaths from lung cancer will occur in 2014. Survival statistics vary depending on the stage of the cancer and when it is diagnosed.

Dr. Shay's research is paid for in part by a five-year grant from NASA, which helps fund cancer research due to cancer risks faced by astronauts during space missions. The findings could lead to more individualized care and pave the way to better, more science-based care and decision making, he said.

"Personalized medicine is coming," Dr. Shay said. "I think this is the future -- patients looking at their risks of cancer recurrence and deciding what to do next. We can better tailor the treatment to fit the individual. That's the goal."

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Gene may predict if further cancer treatments are needed

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Mad Man Manson: Politically Incorrect As Always – Video

Posted: at 12:42 am


Mad Man Manson: Politically Incorrect As Always
For more information on PCW - Preston City Wrestling and forthcoming events please check out the Facebook page: http://www.facebook.com/PrestonCityWrestling ...

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Stephen Colbert's Politically Incorrect Joke Sparks Outrage On Twitter

Posted: at 12:42 am

Though Stephen Colbert intentionally plays an ignorant character on his TV show, some argue his satirical Ching-Chong Ding-Dong Foundation for Sensitivity to Orientals or Whatever went too far.

During Wednesdays show, Colbert made fun of Redskins owner Dan Snyder, who announced a charity organization for Native Americans.

Assuming a simple charity could clear up any politically incorrect hiccups, Colberts character decided to found the Foundation for Sensitivity to Orientals or Whatever. His highly stereotypical character, Ching-Chong Ding-Dong, he then assumed would be acceptable.

I am willing to show [the] Asian community I care by introducing the Ching-Chong Ding-Dong Foundation for Sensitivity to Orientals or Whatever, he tweeted.

Despite the jokes intent, it has since sparked outrage and is trending on Twitter under the hash tag #CancelColbert.

When satire becomes as offensive and hurtful as the thing satirized it is no longer satire, one user tweeted. It is simply more injustice.

Watch the segment here.

Sources: MediaITE, The Blaze

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Movie Review: Youngistaan

Posted: at 12:42 am

Cast: Jackky Bhagnani, Neha Sharma and Farooque Sheikh Director: Syde Ahmad Afzal

Wish it was so easy to become the Prime Minister of India from a pub-hopping youngster. Wish it was so easy to even romance your girlfriend in between official duties and sing songs against the backdrop of the Tajmahal even as the security paid vigil. Wish it was so easy to scuttle opposition within the party and outside it. Wish it was so easy to enjoy a sweeping victory at the polls just by youthful rhetoric and platitudes

Well, debutant director Syed Ahmad Afzal ends up doing just that in Vashu Bhagnanis Youngistaan. Abhminayu Kaul (Jackky Bhagnani), a games developer living in Japan, gives up his well-paying job and freedom to don the Prime Ministers cap just to honour the promise he gave to his terminally ill father (Boman Irani plays the dying PM). Then on the takeover of the nation is as smooth for him as taking over a well-established family business. The only distraction comes in the form of his relentlessly demanding girlfriend Anvita (Neha Sharma), whod rather romance on the streets than become a princess in a castle.

The film seems topical and could have cut across audiences given the current election scenario but lacks the gravitas of a political drama, which particularly associates itself with the highest seat of power. While there are a million problems that a country faces, the acting PMs problem in the film is only dealing with an immature girlfriend who yearns to have matka kulfi at 4 am! And while she loves him enough to accompany him from Japan and even bear his child, for some reason, shes reluctant to marry him, thereby inviting ire of a conservative public.

Performance wise Jackky Bhagnani is earnest though he lacks the lan that is intrinsic to a character of such power. Neha Sharma is confident and pretty and has the potential to etch her way in showbiz. But the most endearing part of the film is the late Farooque Sheikh (plays the PMs assistant Akbar). Natural, unassuming and flawless, hes gone beyond his penned character. Interestingly, the beginning of the film pays a tribute to the late actor by showing clippings of him on the set where he even happens to tell Jackky, Mera last day tumhare last day se pehle hoga!

The films highlight is the Sufi qawwali Daata di diwaani composed by Shiraz Uppal, composed by Shakeel Sohail and sung by Shiraz Uppal and Rafaqat Ali Khan. The number is the soulful oasis in the simplistic film.

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Movie Review: Youngistaan

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FIFA 14 UNNECESASSARY CENSORSHIP FEAT @ITSFANGS @NEPENTHEZ @ZWEBACKHD – Video

Posted: at 12:42 am


FIFA 14 UNNECESASSARY CENSORSHIP FEAT @ITSFANGS @NEPENTHEZ @ZWEBACKHD
FIFA 14 UNNECESASSARY CENSORSHIP FEAT @ITSFANGS @NEPENTHEZ @ZWEBACKHD FIRST ATTEMPT AT A NEW SERIES. LET ME KNOW WHAT YOU THINK. LIKE, SUB, COMMENT Lets get ...

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FIFA 14 UNNECESASSARY CENSORSHIP FEAT @ITSFANGS @NEPENTHEZ @ZWEBACKHD - Video

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Youtube censorship of paedophile playlist warning people of a powerful paedophile network – Video

Posted: at 12:42 am


Youtube censorship of paedophile playlist warning people of a powerful paedophile network
This is the playlist mentioned in the video https://www.youtube.com/playlist?list=PLhRkj0VWgkd0-iY5xB13I_5R8f12pIa2S Article 19. Everyone has the right to fr...

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Youtube censorship of paedophile playlist warning people of a powerful paedophile network - Video

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You Tube Censorship – Video

Posted: at 12:42 am


You Tube Censorship
police state https://www.youtube.com/playlist?list=PLCA0916F44B723C4F feature=mh_lolz experimentalvaccines https://www.youtube.com/watch?v=z-0thf9p1LM.

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You Tube Censorship - Video

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Media freedom: In good health or under threat — how do the US and EU compare? – Video

Posted: at 12:42 am


Media freedom: In good health or under threat -- how do the US and EU compare?
Over a year after the Leveson report came out, regulation of the British press is still a question of intense debate. Meanwhile, the NSA/Snowden revelations ...

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US judge rules Baidu's censorship is protected as free speech

Posted: at 12:42 am

A U.S. judge has ruled that the Chinese search engine Baidu has the right to block pro-democracy works from its query results, dismissing a lawsuit that sought to punish the company for Internet censorship.

The lawsuit against Baidu, originally filed in 2011 by eight activists in New York, claimed that the Chinese search engine had violated U.S. laws on free speech. This was because Baidu had been censoring pro-democracy works on its search engine for not only its users in China, but also for those accessing the site from New York.

The lawsuit demanded Baidu pay US$16 million in damages. But on Thursday, U.S. District Judge Jesse Furman of the U.S. District Court for the Southern District of New York ruled against the activists, and said requiring Baidu to include pro-democracy works in its search results would "run afoul" of the U.S.'s free speech laws.

In his ruling, Furman compared Baidu's blocking of pro-democracy works to a newspaper's right to exercise "editorial control" to publish what it wants. In Baidu's case, the company has created a search engine that favors certain political speech.

"The First Amendment protects Baidu's right to advocate for systems of government other than democracy [in China or elsewhere] just as surely as it protects Plaintiffs' rights to advocate for democracy," wrote Furman.

Baidu is also not stopping U.S. users from accessing the pro-democracy works through other search engines such as Google or Bing, the judge added.

On Friday, the Chinese search company did not immediately respond to a request for comment. But the law firm representing Baidu in the case said the ruling was a victory for the free speech rights of Internet search engines.

"It shows that our courts protect the right of all media to choose what they publish," said attorney Carey Ramos in a statement. "That right extends to Internet media as well as print media. And it protects Chinese media as much as American media."

The activists who filed the lawsuit against Baidu could not be reached for comment.

Last year in March, Furman had initially dismissed the lawsuit because Baidu was not properly served court papers, but later the case was allowed to proceed.

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US judge rules Baidu's censorship is protected as free speech

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U.S. judge rules Baidu's censorship is protected as free speech

Posted: at 12:42 am

A U.S. judge has ruled that the Chinese search engine Baidu has the right to block pro-democracy works from its query results, dismissing a lawsuit that sought to punish the company for Internet censorship.

The lawsuit against Baidu, originally filed in 2011 by eight activists in New York, claimed that the Chinese search engine had violated U.S. laws on free speech. This was because Baidu had been censoring pro-democracy works on its search engine for not only its users in China, but also for those accessing the site from New York.

The lawsuit demanded Baidu pay US$16 million in damages. But on Thursday, U.S. District Judge Jesse Furman of the U.S. District Court for the Southern District of New York ruled against the activists, and said requiring Baidu to include pro-democracy works in its search results would run afoul of the U.S.s free speech laws.

In his ruling, Furman compared Baidus blocking of pro-democracy works to a newspapers right to exercise editorial control to publish what it wants. In Baidus case, the company has created a search engine that favors certain political speech.

The First Amendment protects Baidus right to advocate for systems of government other than democracy [in China or elsewhere] just as surely as it protects Plaintiffs rights to advocate for democracy, wrote Furman.

Baidu is also not stopping U.S. users from accessing the pro-democracy works through other search engines such as Google or Bing, the judge added.

On Friday, the Chinese search company did not immediately respond to a request for comment. But the law firm representing Baidu in the case said the ruling was a victory for the free speech rights of Internet search engines.

It shows that our courts protect the right of all media to choose what they publish, said attorney Carey Ramos in a statement. That right extends to Internet media as well as print media. And it protects Chinese media as much as American media.

The activists who filed the lawsuit against Baidu could not be reached for comment.

Last year in March, Furman had initially dismissed the lawsuit because Baidu was not properly served court papers, but later the case was allowed to proceed.

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U.S. judge rules Baidu's censorship is protected as free speech

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