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Category Archives: Transhuman News

Great Branding Is Invisible

Posted: April 21, 2014 at 5:43 pm

The devil is in the detail is a clich that happens to be true, but lets turn it around: The magic is in the detail. What constitutes quality in a product, besides the raw materials you choose? The attention paid to detail.

Look at a knock-off Gucci handbag and consider its original counterpart: The difference, besides the leather chosen, is in the stitching, the inside lining, the zippers, and so on. In short, quality resides in the hidden details that aren't obvious to most--until you touch the product and look at it up close. It's craftsmanship that gives luxury fashion brands longevity and which lets them weather trends.

Brands are no different from the products and services that they represent. Frantically searching for the one Unique Positioning Statement (UPS) or logo design that is going to simultaneously sum up precisely what your company stands for and differentiate it from the rest of the pack is in some ways a meaningless battle. Taglines may be catchy, but they don't, in the end, make people buy products. What determines whether a woman buys Chanel No. 5 or Issey Miyake's L'Eau d'Issey Florale? Not taglines but how either smells on her skin.

What makes you so special?

What makes your brand unique and better than the competition is the compounded totality of many little things. That means you cant just consider the attention given to producing an outstanding service or product--you also have to think about how the sales force and support team treats its customers and how the receptionist answers the phone.

The Jawbone UP24 fitness tracking device is a good example. After diligently tracking my sleep, workout regime, and diet, I became properly addicted to the wristband and to its accompanying iOS app. When the band suddenly stopped working, after three months, I flew into a minor panic. All my data (and exercise momentum) would be lost, I worried. But Jawbone turned out to have an excellent support system. They troubleshot the problem with me seamlessly, on email and over the phone. They used human beings, not robots. I followed the progress of my issue via a concise thread on their support ticketing system. After they quickly exhausted all possible solutions and saw that the device was still malfunctioning, they shipped me a replacement band immediately. I became loyal to the brand thanks to the humane and efficient treatment I received. The extra attention taken by Jawbone to make sure that their staff was professional and courteous--while making sure that I never got lost in a maze of telephone drones or automated emails--made a huge difference.

Keep the details invisible.

Its the combination of myriad details that shapes brand image in the minds of customers. These details may be transmitted subconsciously. Not everyone recognizes that hand stitching makes a serious difference. Expertly executed details, imperceptible to most, should create a sense of magic and wonder. Think of an upmarket German car, such as an Audi, BMW or Mercedes. When you are at the BMW showroom and you step into, say, a 5 Series model, the satisfyingly clean thumpf sound that the door makes as you shut it signifies quality. Theres no rattling, no sound of sheet metal being slammed, just that confidence-inspiring, compact sound. Its the sound of outside noise and discomfort being sealed off while you enter a safe, comfortable place. Behind the steering wheel are carefully wrought details, too: the smell, the way the seat feels, the feel of your hands on the steering wheel, the way the dashboard buttons have a certain resistance, and so on.

For those who remember, think about the perfect resistance and muted click of the Hewlett-Packard scientific calculator buttons, compared to their competitors Casio and Texas Instruments. The latter two companies clearly hadnt spent a lot of energy thinking about what it would feel like to press down the keys. And it made a difference.

Advertising and branding should be thought of in the same way. Yes, the big idea is important, but success hinges on its execution, consistency, and attention to each and every word. Do define the brand with succinct messaging, but also trust that consumers will recognize the collective positive attributes of the brand rather than just its tagline. Make sure your communications are well crafted and recognizable. All touch points need to be carefully considered, down to every HTML email campaign.

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Great Branding Is Invisible

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Will Your Eczema Nummular Skin Spread? 4 Quick Fixes to Stop That Happening Today – Video

Posted: at 5:42 pm


Will Your Eczema Nummular Skin Spread? 4 Quick Fixes to Stop That Happening Today
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Will Your Eczema Nummular Skin Spread? 4 Quick Fixes to Stop That Happening Today - Video

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How To Cure Eczema In Babies (The Final Piece Of Puzzle) – Video

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How To Cure Eczema In Babies (The Final Piece Of Puzzle)
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How To Cure Eczema In Babies (The Final Piece Of Puzzle) - Video

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Natural Eczema Treatments – Video

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Natural Eczema Treatments
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Psoriasis Eczema Dry Skin Your Story #38 – Video

Posted: at 5:42 pm


Psoriasis Eczema Dry Skin Your Story #38
Your story is similar to my story I tell in this video.

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Gene link found in colorectal cancer risk from processed meats

Posted: at 5:42 pm

Love your regular ham sandwich or grilled sausages? Experts say those who consume too much processed meat risk a higher chance of colorectal cancer if they possess a common gene variant identified as GATA3.

According to Dr. Jane Figueiredo, of the Keck School of Medicine at the University of Southern California, the new study published in PLOS Genetics is the first to understand whether some individuals are at higher or lower risk based on their genomic profile.

"This information can help us better understand the biology and maybe in the future lead to targeted prevention strategies" said Dr Figueiredo.

Pointing out that"diet is a modifiable risk factor for colorectal cancer",Dr Figueiredo andthe research team expanded on earlier studies ondiet, especially one that's high in red or processed meat and colorectal cancer risk.

The team looked at more than 9,000 colorectal cancer cases and a similar number of controls and the interaction between red meat, processed meat, fiber, fruit and vegetables, and colorectal cancer risk.

They founda significant interaction between the genetic variant "rs4143094"linked to a gene called GATA3and processed meat.

"The possibility that genetic variants may modify an individual's risk for disease based on diet has not been thoroughly investigated but represents an important new insight into disease development," concludes Dr. Li Hsu, the lead statistician on the study.

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Gene link found in colorectal cancer risk from processed meats

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A gene within a gene contributes to the aggressiveness of acute myeloid leukemia

Posted: at 5:42 pm

PUBLIC RELEASE DATE:

21-Apr-2014

Contact: Darrell E. Ward Darrell.Ward@osumc.edu 614-293-3737 Ohio State University Wexner Medical Center

COLUMBUS, Ohio A small gene that is embedded in a larger, well-known gene is the true leukemia-promoting force usually attributed to the larger gene, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC James).

The findings are published in the journal Science Signaling.

The larger host gene is called BAALC (pronounced "Ball C"). The smaller embedded gene is called microRNA-3151 (miR-3151). The study investigated the degree to which each of the genes contributes to the development of acute myeloid leukemia (AML).

"We discovered that the smaller microRNA gene, and not the larger host gene, is the major oncogenic driver of the two molecules in AML," says principal investigator Albert de la Chapelle, MD, PhD, professor of Medicine and the Leonard J. Immke Jr. and Charlotte L. Immke Chair in Cancer Research.

"When both genes are highly expressed, it means a bad prognosis for patients, but our experiments indicate that it is high expression of miR-3151 that really matters. Overexpression of BAALC alone had only limited cancer-causing activity," he says.

The researchers discovered that miR-3151 promotes the development of leukemia by blocking a gene called TP53. Normally, TP53 is a central "tumor-suppressor" gene that protects against cancer by causing a cell with serious gene damage to self-destruct. "When miR-3151 blocks TP53 in the tumor cells, it enables the cells to survive, divide and grow faster," says co-senior author Clara D. Bloomfield, MD, Distinguished University Professor and Ohio State University Cancer Scholar.

"We also show that miR-3151 promotes growth in malignant melanoma cells in the same way, suggesting that the molecule might play a role in solid-tumor development," says Bloomfield, who is also senior adviser to the OSUCCC James and holds the William Greenville Pace III Endowed Chair in Cancer Research.

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A gene within a gene contributes to the aggressiveness of acute myeloid leukemia

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The Politically Incorrect Truth About the French Revolution Part III – Video

Posted: at 5:42 pm


The Politically Incorrect Truth About the French Revolution Part III
The politically incorrect truth about the French Revolution, focusing on the revolution itself which the facts show was not necessary, not productive and not...

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Staff Bundy Ranch LDS Mormon Jake Harris Censorship – Video

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Staff Bundy Ranch LDS Mormon Jake Harris Censorship
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Staff Bundy Ranch LDS Mormon Jake Harris Censorship - Video

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Unreasonable Censorship Ep.2 – Fun on Galaxy! – Video

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Unreasonable Censorship Ep.2 - Fun on Galaxy!
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