Category Archives: Transhuman News

John Sterling | 05/01/2014

The following article, reproduced in full below, was originally published at Genetic Engineering & Biotechnology News.

Its been a hot year for biotech! As G. Steven Burrill, CEO of Burrill & Co., noted in a recent report, life science firms raised $2.9 billion in new equity capital globally from public investors in February. This included $1.1 billion raised by 18 companies that completed initial public offerings and $1.8 billion raised by 23 companies that completed follow-on offerings during the month.

In the U.S., 16 life sciences companies raised $959 million through IPOs and 22 companies raised $1.75 billion through follow-on offerings on U.S. exchanges during February, making the month the biggest for IPOs in terms of the number of completed deals since February 2000!

Why the excitement? Promising new biotherapeutics are emerging from the drug pipeline. Advances in stem cell research and regenerative medicine are occurring at a rapid pace. And OMICS technologies (e.g., genomics, proteomics, metabolomics, transcriptomics, glycomics, and lipomics), originally developed and used in the lab, are now making their way into clinical medicine, truly ready to usher in an era of personalized medicine.

The 2014 BIO International Convention will be held in San Diego this June. As usual, the BIO conference committee did a superb job in putting together a first-class program that covers a wide range of topics with something to offer everyone involved in biotech R&D or commercialization. Its been a tough call this year but here are my picks for the top 10 cant miss sessions at the conference.

To learn more about the program and available registration packages for Convention, please visithere

John Sterling is editor-in-chief of Genetic Engineering & Biotechnology News (GEN).

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GENs Top 10 Session Picks for the 2014 BIO International Convention

Today virtually everything we eat is produced from seeds that have been genetically altered in some way. New methods of plant tinkering have emerged over the generations and so, too, have the fears

Today virtually everything we eat is produced from seeds that have been genetically altered in one way or another. Credit: Thinkstock

Editor's note: The following is the introduction to the May 2014 issue of Scientific American Classics: The Birth of the Great GMO Debate.

The idea of intentionally infecting a plant with a bacterium might seem strange. Just three decades ago, however, researchers discovered that they could use this infection to deliver new and potentially useful genes into crops.

What has long appeared to be simply the agent of a bothersome plant disease is likely to become a major tool for the genetic manipulation of plants: for putting new genes into plants and thereby giving rise to new varieties with desired traits, announced acclaimed scientist Mary-Dell Chilton in 1983 in a pioneering article, one of many in this collection from the archives of Scientific American. Today genes introduced this way are yielding some of the most exciting new approaches to food securityas well as a hearty amount of debate.

Despite the excitement about the potential benefits of genetic engineering 30 years ago, the broader historical perspective highlighted in this collection reveals that this is just one of many thrilling and surprising advances in the long history of plant genetic alteration, which began well before this retrospective issue could document. (Scientific American extends back only to 1845.) Consider the assessment of the new technology of cross-pollination described in 1717 by botanist Richard Bradley: A curious person may by this knowledge produce such rare kinds of plants as have not yet been heard of.

For 10,000 years, in fact, we have altered the genetic makeup of our crops. For example, the ancient ancestor of modern corn was created some 6,000 years ago by Native Americans who domesticated a wild plant called teosinte, which looks nothing like a modern corn plant. If humans still depended on this wild relative, we would need hundreds, if not thousands, of times more plantsand acresto replace corn.

Today virtually everything we eat is produced from seeds that have been genetically altered in one way or another. The old approaches were crude and have been refined over the centuries. Modern methods include grafting and forced pollination (mixing genes of distantly related species) and radiation treatments to create random mutations in seeds. The newest method is genetic engineeringa technology developed after scientists observed that the bothersome plant pathogen Agrobacterium tumefaciens habitually introduced its own genes into plants. With a little laboratory work, the bacterium can instead implant desirable genes, such as those that increase nutrients or help the plant resist pests or drought.

The planting of genetically engineered crops during the past 20 years has drastically reduced the amount of synthetic insecticides sprayed worldwide, shifted the use of herbicides to those that are less toxic, rescued the U.S. papaya industry from disease, and benefited the health and well-being of farmers and their families and consumers. Every scientific review of the crops on the market so far has concluded that the plants are safe to eat.

Just as the excitement surrounding the benefits of genetic engineering paralleled those of our predecessors, so, too, has the fear of plant tinkering technologies persisted over time. Consider the comments of Maxwell T. Masters, president of the International Conference of Hybridization, in his 1899 Scientific American article: Many worthy people objected to the production of hybrids on the ground that it was an impious interference with the laws of Nature. Today we are all too familiar with similar arguments about the application of genetic engineering in agriculture.

See more here:
Plant Engineers Sow Debate