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Category Archives: Transhuman News

"Heredity is Not Destiny": Breastfeeding, Birth Control Pills May Reduce Ovarian Cancer Risk Among Women with BRCA …

Posted: May 15, 2014 at 12:42 am

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Newswise PHILADELPHIA Breastfeeding, tubal ligation also known as having ones tubes tied and oral contraceptives may lower the risk of ovarian cancer for some women with BRCA gene mutations, according to a comprehensive analysis from a team at the University of Pennsylvania's Basser Research Center for BRCA and the Abramson Cancer Center. The findings, a meta-analysis of 44 existing peer-reviewed studies, are published in the Journal of the National Cancer Institute.

The researchers, from Penn's Perelman School of Medicine, found that breastfeeding and tubal ligation are associated with reduced rates of ovarian cancer in BRCA1 mutation carriers, and the use of oral contraceptives is associated with a reduced risk of ovarian cancer in patients with BRCA1 or BRCA 2 mutations. The analysis also helped better define factors that may increase risk among this population: Smoking, for instance, may raise the risk of breast cancer for patients with a BRCA2 mutation. Though the team cautions that more data are required before definitive conclusions about these variables can be made, the findings help to shed light on non-surgical risk reduction options for women who may not be ready to undergo prophylactic removal of their ovaries to cut their cancer risk.

Our analysis reveals that heredity is not destiny, and that working with their physicians and counselors, women with BRCA mutations can take proactive steps that may reduce their risk of being diagnosed with ovarian cancer, says lead author Timothy R. Rebbeck, PhD, professor of Epidemiology and Cancer Epidemiology and Risk Reduction Program Leader at Penn Medicine's Abramson Cancer Center. The results of the analysis show that there is already sufficient information indicating how some variables might affect the risk of cancer for these patients."

BRCA1 and BRCA2 are human genes that produce tumor-suppressing proteins. A woman's risk of developing breast or ovarian cancer is notably increased if she inherits a harmful mutation in either the BRCA1 gene or the BRCA2 gene from either parent. Fifty-five to 65 percent of women who inherit a harmful BRCA1 mutation, and about 45 percent of women who inherit a harmful BRCA2 mutation will develop breast cancer by age 70, compared to approximately 12 percent of women in the general population. Thirty-nine percent of women who inherit a harmful BRCA1 mutation and up to 17 percent of women who inherit a harmful BRCA2 mutation will develop ovarian cancer by age 70, compared to only 1.4 percent of women in the general population. Both BRCA mutations have also been associated with increased risks of several other types of cancer.

Though the study's findings point to a helpful role for birth control pills in cutting ovarian cancer risk, the relationship between oral contraceptives and breast cancer risk was ambiguous. The authors say women and their health care providers should weigh the potential benefits of oral contraceptives (reduction in ovarian cancer risk, avoidance of unintended pregnancy, and regulation of menstrual cycles, for instance) against the potential risks (such as blood clots or the possible increased risk of breast cancer). There was also insufficient evidence to draw conclusions about the relationships between breastfeeding and tubal ligation, respectively, and breast cancer. Future research aims to examine these issues as well as how other variables, such as alcohol consumption, affect the risk of breast and ovarian cancer for BRCA mutation carriers. Since BRCA testing is relatively new, researchers have struggled to conduct large studies to examine these trends due to limited availability of large numbers of prospectively identified BRCA1/2 mutation carriers.

Patients deserve better cancer-risk reduction options than surgically removing their healthy breasts and ovaries, said Susan Domchek, MD, executive director of the Basser Research Center for BRCA and co-author on the new paper. Its imperative that we continue examining and building upon past research in this area so that we can provide BRCA mutation carriers with options at every age, and at every stage of their lives.

Penn's Tara M. Friebel, MPH, is also an author of the paper.

Funding for the study was supported by the National Institutes of Health (R01-CA102776 and P50-CA083638) and the Basser Research Center for BRCA, the nation's first and only comprehensive center focused on prevention and treatment of BRCA-related cancers. In 2012, University of Pennsylvania alumni Mindy and Jon Gray gave a $25 million gift to establish the Basser Center in honor of Mindys sister, Faith Basser, who passed away at the age of 44 of ovarian cancer. Recently, the Grays committed an additional $5 million gift to support BRCA-related pancreatic cancer research as well as launch an external grants program to help advance science around the globe focused on BRCA-related research.

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"Heredity is Not Destiny": Breastfeeding, Birth Control Pills May Reduce Ovarian Cancer Risk Among Women with BRCA ...

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Unnecessary Censorship – Avatar: The Last Airbender – Video

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Unnecessary Censorship - Avatar: The Last Airbender
Well, I felt like doing it so I did it. Here you go! I unnecessarily censored my favourite cartoon show of all time, I give you; "Unnecessary Censorship - Avatar: The Last Airbender". Avatar...

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Censorship BANS ‘The Xpose’ from EXPOSING – Video

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Censorship BANS #39;The Xpose #39; from EXPOSING
Yo Yo Honey Singh Himesh Reshamiya #39;s The Xpose under censorship scruntiny for BOLD Content -- Sonali Raut #39;s transparent Saree Subscribe now to watch more of Bollywood Hangover Videos http://www....

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THOR: THE DARK WORLD | Unnecessary Censorship Recap | Censored Marvel Funniest / Best Moments – Video

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THOR: THE DARK WORLD | Unnecessary Censorship Recap | Censored Marvel Funniest / Best Moments
In anticipation of the Guardians of the Galaxy and the Avengers 2: Age of Ultron by Disney... I mean Marvel... let #39;s take a look back at a recap / synopsis of the 2013 Thor: the Dark World...

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THOR: THE DARK WORLD | Unnecessary Censorship Recap | Censored Marvel Funniest / Best Moments - Video

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Gang of 4: Wolfgang Halbig and the Sandy Hook Circus! Youtube Censorship! – Video

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Gang of 4: Wolfgang Halbig and the Sandy Hook Circus! Youtube Censorship!
Another lively Go4 discussion featuring +kateslate11 +freeagentmedia +redpillrevolution +freeradiorevolution Join the discussion below!

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Lisle museum exhibit to explore film censorship in Chicago

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LISLE A Lisle native, museum curator and 22-year-old college student has joined forces with his North Central College professor to create an exhibit exploring the history of Chicago film censorship.

Brian Failing, a senior at North Central, cowrote an upcoming exhibit at the Lisle Station Museum with associate professor of speech communication and coordinator for the college's urban and suburban studies program, Steve Macek, called, "Banned in Chicago: Eight Decades of Film Censorship in the Windy City."

The exhibit is the result of research the two conducted for a book Macek is working on. Failing was Macek's research assistant over the course of two summers.

"He was very excited about the research we were doing on the history of film censorship in Chicago," Macek said. "He thought it would make a compelling exhibit."

Failing has worked at the museum since he was 15 years old, and took over as curator his senior year of high school.

"I thought (film censorship) was a topic that's really important and really interesting that I think a lot of people will like, because everyone likes stuff that has to do with films, movies and Hollywood," Failing said.

In 1907, Chicago became the first city in the country to create a local film censorship authority, Macek said. The city also had the longest-lasting such authority in the country it was dissolved in 1984 after funding for the agency stopped.

"When it was first created, the police chief the head of Chicago police was responsible for reviewing and licensing films," Macek said. "Any films that were amoral or obscene could be banned."

About a decade after the agency was created, Macek said the authority was delegated to a civilian board, which was usually chaired by a police officer. The other members of the board were often women.

"The thinking was that women had a stronger moral sense than men and were better able to determine what was suitable," Macek said.

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Wikipedia's Jimmy Wales blasts ruling forcing Google to erase search results

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Wikipedia founder Jimmy Wales has hit out at a European ruling on the "right to be forgotten." Joi Ito/Wikimedia Commons

Wikipedia founder Jimmy Wales has hit out at a new European ruling forcing Google to edit or erase search results, calling it "wide-sweeping censorship."

Speaking to the BBC, Wales described the European Union Court of Justice's decision on Tuesday as "one of the most wide-sweeping internet censorship rulings that I've ever seen."

The ruling enshrines the "right to be forgotten", which allows individuals to request the removal of links to irrelevant or incorrect information about themselves. The ruling means that instead of trying to get an offending article, photo or online posting removed by whoever published it, the subject of that article or posting can contact Google and ask for the posting to be removed from search results.

But Wales is sceptical about the practicality of the ruling. "If you really dig into it, it doesn't make a lot of sense," he said. Users of the Internet can "complain about something and just say it's irrelevant, and Google has to make some kind of a determination about that. That's a very hard and difficult thing for Google to do, particularly if Google is at risk of being held legally liable if it gets it wrong in some way."

"If they have to start coping with everybody who whines about a picture they posted last week, it's going to be very difficult for Google," he added.

The ruling is designed to protect the privacy of the individual. The case came to the top European court following hundreds of cases regarding the right to be forgotten in Spain, including a complaint by a man claiming his privacy was infringed by a notice related to the repossession of his house.

The right to be forgotten is meant to protect, for example, an individual wrongly accused of a crime. Reports of the allegations are posted online and stay there, hanging around accusingly even if the person is later acquitted. Under the new laws, the person could ask Google to edit or remove links to the allegations.

But the decision could also be abused by people who want to cover up their misdeeds or indiscretions -- especially if they're in a position to afford lawyers.

Google said the European Court's decision was "disappointing", and is now taking time to "analyse the implications." But Jimmy Wales doesn't see much of a future for the ruling: "I suspect this isn't going to stand for very long," he said.

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Ron Paul House Financial Subcmte Hearing Federal Reserve Disclosure Pt 8 of 13webm – Video

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Ron Paul House Financial Subcmte Hearing Federal Reserve Disclosure Pt 8 of 13webm

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Ron Paul House Financial Subcmte Hearing Federal Reserve Disclosure Pt 4 of 13webm – Video

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Ron Paul House Financial Subcmte Hearing Federal Reserve Disclosure Pt 4 of 13webm

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Ron Paul House Financial Subcmte Hearing Federal Reserve Disclosure Pt 12 of 13webm – Video

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Ron Paul House Financial Subcmte Hearing Federal Reserve Disclosure Pt 12 of 13webm

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