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Category Archives: Transhuman News
CCHK2014-2015D.N.A. PART 1 – Video
Posted: September 26, 2014 at 10:44 am
CCHK2014-2015D.N.A. PART 1
"-" Golden Dynamic "Taylor Swift-We Are Never Ever Getting Back Together" UMG "BIGBANG-BIGBANG 2012" YG Entertainment...
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CCHK2014-2015D.N.A. PART 1 - Video
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Change DNA – The 8 Principles of Change – Video
Posted: at 10:44 am
Change DNA - The 8 Principles of Change
Ever wonder how some organizations adapt gracefully or even thrive in a changing environment while most others crack and buckle under the same conditions? We did too. And since so many...
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Change DNA - The 8 Principles of Change - Video
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DNA/RNA Isolation Kit purifies nucleic acid.
Posted: at 10:44 am
September 26, 2014 - Used with Eppendorf epMotiona automated pipetting system and other similar automation platforms, PowerMag Airand Water DNA/RNA Isolation Kit provides automated, hands-free purification of nucleic acids from filtered air and water samples. Bead-based lysis ensures uniform representation of nucleic acid population. By completely removing PCR inhibitors found in turbid or contaminated water, Inhibitor Removal Technology eliminates false negatives in downstream applications. MO BIO Laboratories, Inc. 2746 Loker Avenue West Carlsbad, CA, 92010 USA Press release date: September 19, 2014
CARLSBAD, Calif., -- MO BIO Laboratories, Inc., the leader in soil, water and microbial nucleic acid purification, announces the launch of the PowerMag Air & Water DNA/RNA Isolation Kit, for automated, hands-free purification of nucleic acids from filtered air and water samples using the Eppendorf epMotiona automated pipetting system and other similar automation platforms.
The PowerMag Air & Water DNA/RNA Isolation Kit is the latest in the high quality nucleic acid purification tools developed using key MO BIO technologies:
-- Unique bead-based lysis for uniform representation of the nucleic acid population -- Inhibitor Removal Technology (IRT) for complete removal of PCR inhibitors commonly found in turbid or contaminated water (for example, humic substances, metals and petroleum) to eliminate false negatives in downstream applications such as qPCR -- ClearMag technology: Magnetic beads designed with a unique coating that enables hands-free purification of high yields of pure nucleic acids in a high-throughput format
The PowerMag Air & Water DNA/RNA Isolation Kit is an extension of MO BIO's PowerWater line of DNA and RNA isolation kits, which are the first choice of environmental agencies and public health departments for applications such as air and water quality monitoring. The kit is compatible with air and water samples collected on a variety of filter membrane types including mixed cellulose ester, polyethersulfone, polycarbonate and nylon.
The PowerMag Air & Water DNA/RNA Isolation Kit is available now. For more information, visit the MO BIO website (www.mobio.com/ water-dna-isolation/ powermag-air-water-dna-rna-isolation-kit-optimized-for-epmotion.html) or call 800-606-6246.
MO BIO Laboratories, Inc. (http://www.mobio.com) has developed innovative tools for researchers in molecular biology since 1993. A global leader in solutions for soil, water and microbial nucleic acid purification, MO BIO's Power kits contain patented Inhibitor Removal Technology for removal of PCR inhibiting substances during the nucleic acid purification procedure. At MO BIO Laboratories, Inc., our focus is quality products that work, save time and function for all sample types, not just the easy ones. It is MO BIO's aim to make researchers' working lives more productive and efficient, creating time to focus on what is critical, not just in work, but in life.
CONTACT: Heather Martinez, Senior Product Marketing Manager, MO BIO Laboratories, Inc., 760-929-9911
Web Site: http://www.mobio.com
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DNA/RNA Isolation Kit purifies nucleic acid.
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Prosecutors obtain warrant for fresh DNA in 83 slaying
Posted: at 10:44 am
Published: Friday, 9/26/2014
BY JENNIFER FEEHAN BLADE STAFF WRITER
When Andrew Gustafson was indicted last year for the 1983 slaying of a Whitehouse woman, the charges rested squarely on DNA evidence linking Mr. Gustafson to the crime.
This week, prosecutors sought to clear up any possible legal problems with the DNA sample obtained from Mr. Gustafson in 2007. The sample was taken without a search warrant in connection with an unrelated sexual assault investigation and stored for more than three years in the desk drawer of now-retired Lucas County sheriffs Detective Cathy Stooksbury.
On Monday, prosecutors sought and obtained a search warrant to get a new DNA swab from Mr. Gustafson, 57, of Birch Run, Mich., who is being held in the Lucas County jail on a $1 million bond. He is charged with alternate counts of aggravated murder and one count of murder in the death of Janean Brown, 19, whose body was found Nov. 19, 1983, in a ditch near Mr. Gustafsons home. Her throat had been cut.
We wanted to take any question about what [former Detective] Stooksbury did out of play, said J. Christopher Anderson, an assistant prosecutor assigned to Mr. Gustafsons case. We still think what she did was right and proper, but we dont want the defense to raise doubts about, Are you sure its his DNA?
Ms. Stooksbury testified at a hearing last month on Mr. Gustafsons motion to suppress the DNA evidence, saying she knew he had been a suspect in the Brown case even though he was never charged. She told the court she obtained, but never tested, his DNA in connection with a sexual assault complaint she was investigating, then kept his DNA sample in her locked desk drawer because she didnt want it to disappear.
According to an affidavit filed with Mondays search warrant application, the DNA swab collected by Ms. Stooksbury in 2007 was given to the cold-case unit in 2011 when the unit reopened the Janean Brown investigation. The 2007 DNA swab was tested as a precaution in avoidance of alerting Mr. Gustafson that the case had been reopened, the affidavit states.
The Ohio Bureau of Criminal Investigation conducted the DNA testing, concluding that DNA from a vaginal swab taken from Ms. Brown was consistent with Mr. Gustafsons DNA. Testing also revealed that a Merit cigarette butt found in the ash tray of Mr. Gustafsons van in 1983 contained DNA consistent with Ms. Browns.
In two subsequent interviews with Mr. Gustafson by cold-case detectives, he still maintains he did not know Janean Brown, she was never in his van, and he has never had sexual relations with her, the affidavit states.
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Prosecutors obtain warrant for fresh DNA in 83 slaying
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Researchers engineer 'Cas9' animal models to study disease, inform drug discovery
Posted: at 10:44 am
Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments. The researchers successfully used the new "Cas9 mouse" model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers. The mouse has already been made available to the scientific community and is being used by researchers at more than a dozen institutions. A paper describing this new model and its initial applications in oncology appears this week in Cell.
In recent years, genetic studies have found thousands of links between genes and various diseases. But in order to prove that a specific gene is playing a role in the development of the disease, researchers need a way to perturb it -- that is, turn the gene off, turn it on, or otherwise alter it -- and study the effects.
The CRISPR-Cas9 genome-editing system is one of the most convenient methods available for making these alterations in the genome. While the tool is already being used to test the effects of mutations in vitro -- in cultured cell lines, for instance -- it is now possible to use this tool to study gene functions using intact biological systems.
The CRISPR-Cas9 system relies on two key features to edit the genome: Cas9, a "cleaving" enzyme capable of cutting DNA; and guide RNA, a sequence that directs Cas9 to the DNA target of interest in the genome. However, the Cas9 enzyme presents some delivery challenges for in vivo applications.
"By equipping the mouse with Cas9, we relieved the burden of delivery. This frees up space for the delivery of additional elements -- whether by viruses or nanoparticles -- making it possible to simultaneously mutate multiple genes and even make precise changes in DNA sequences," said Randall Platt, a graduate student at MIT working at the Broad Institute in the lab of Feng Zhang, an assistant professor at the McGovern Institute for Brain Research at MIT, and a core member of the Broad Institute. Platt and Sidi Chen, a postdoctoral fellow at MIT's Koch Institute for Integrative Cancer Research working in the lab of Institute Professor Phillip Sharp, were co-first authors of the paper.
This ability to perturb multiple genes at the same time may be particularly useful in studying complex diseases, such as cancer, where mutations in more than one gene may be driving the disease. To demonstrate a potential application for cancer research, the authors used the "Cas9 mouse" to model lung adenocarcinoma. Previously, scientists working with animal models have had to knock out one gene at a time, or cross animal models to produce one with the needed genetic modifications, processes that are challenging and time consuming.
"The 'Cas9 mouse' allows researchers to more easily perturb multiple genes in vivo," said Zhang, who, along with Sharp, served as co-senior author of the Cell paper. "The goal in developing the mouse was to empower researchers so that they can more rapidly screen through the long list of genes that have been implicated in disease and normal biological processes."
Researchers contributing to the paper also found that cells derived from the "Cas9 mouse" could be extracted for use in lab experiments and were able to leverage the Cas9-expressing cells to edit immune dendritic cells even after the cells had been removed from the mouse, allowing the researchers to experiment with cells that aren't easily accessible and often lack the shelf life to conduct such experiments.
"As we demonstrated with immune cells, the mouse allows us to experiment with cells that only remain viable for a few days ex vivo by leveraging the fact that they already express Cas9. Absent the expression of Cas9, we would not have sufficient time for the CRISPR system to work its magic," said Broad core member and paper co-author Aviv Regev, who is an associate professor of biology at MIT. Regev's lab, along with the lab of Broad senior associate member Nir Hacohen (a faculty member at Massachusetts General Hospital and Harvard Medical School), used the mouse to investigate dendritic cells, as reported in the Cell study.
"Genetic manipulation is one of the most critical tools we have for investigating complex circuits, and the 'Cas9 mouse' will help us do it more effectively," said Regev.
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Hainan declared as "World Longevity Island"
Posted: at 10:43 am
The southern tourist resort of Hainan now has another attraction to woo global tourists - the chance to live longer.
The island province has been declared as a World Longevity Island by the International Expert Committee on Population Aging and Longevity (ISCPAL), according to a press conference held by the provincial government on Thursday.
Alongside South Korea's Jeju Island, Hainan was named one of the world's two longevity islands thanks to its outstanding natural environment and social welfare system. The committee decided to honor the province after conducting field research in 17 towns and counties in 2013.
Hainan trumpets a record of more than 1,900 centenarians, and about 1.2 million residents above the age of 60 by the end of 2013, amounting for about 13.36 percent of its total population, according to the the provincial committee on aging. By 2015, the number of octogenarians is expected to reach 170,000.
The tropical island is bestowed with high-quality air and water. A study by the ISCPAL showed that the hair of Hainan's centenarians has ample trace elements, which are beneficial to human health. For instance, the soil and produce in Chengmai county in western Hainan are rich in selenium.
A couple of localities in Hainan had already been branded as "Longevity Cities" before the island was honored, including Chengmai and the forest-rich Wanning. Wenchang City is also famed as one of the country's top longevity spots.
The latest certification is likely to give Hainan extra firepower in the tourism market and stir a new round of health tourists, as has been the case for other places known for longevity in the country.
Last year, media in China reported a huge number of tourists traveling to the famous Bama County, south China's Guangxi Zhuang Autonomous Region to seek the recipe for a long life. The county's "longevity pilgrims" can be seen crawling around on four-legs and are even known to drink urine, believing the practices help keep illness at bay.
The reputation of the remote county is so widespread that it has even attracted a number of people who travel from far away to live in Bama.
This group is nicknamed "houniaoren," or "migratory people," with lives like those of migratory birds -- flying south in winter and staying in Bama for several months.
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Hainan declared as "World Longevity Island"
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What Can Help Psoriasis – Video
Posted: at 10:43 am
What Can Help Psoriasis
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What Can Help Psoriasis - Video
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Dermarest Psoriasis Medicated Moisturizer Review – Video
Posted: at 10:43 am
Dermarest Psoriasis Medicated Moisturizer Review
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Dermarest Psoriasis Medicated Moisturizer Review - Video
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Dry Skin Treatment New Treatment For Psoriasis – Video
Posted: at 10:43 am
Dry Skin Treatment New Treatment For Psoriasis
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Dry Skin Treatment New Treatment For Psoriasis - Video
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How To Treat Psoriasis Get Rid of Psoriasis in Less Than Two Weeks – Video
Posted: at 10:43 am
How To Treat Psoriasis Get Rid of Psoriasis in Less Than Two Weeks
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How To Treat Psoriasis Get Rid of Psoriasis in Less Than Two Weeks - Video
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