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Category Archives: Transhuman News

All kinds of dna repair mechanism-animation – Video

Posted: October 6, 2014 at 3:43 pm


All kinds of dna repair mechanism-animation

By: SAHIL SANGHVI

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All kinds of dna repair mechanism-animation - Video

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MB lecture 10-16 making DNA copies – Video

Posted: at 3:43 pm


MB lecture 10-16 making DNA copies

By: Vicky Shemer

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MB lecture 10-16 making DNA copies - Video

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DNA ties 2004 rape to Arlington man who told victim, 'Don't let this affect your life'

Posted: at 3:43 pm

An Arlington man has been sentenced to 50 years in prison for kidnapping and raping a 19-year-old woman at gunpoint a decade ago.

The case went cold for years until DNA evidence tied 56-year-old Charles Green to the crime, according to the Tarrant County district attorney's office.

"This defendant walked the same streets as his victim for 10 years," prosecutor Kim D'Avignon said. "Now, thanks to DNA, the hard work of the Pantego Police Department, and this Judge's sentence, he will never walk the streets again."

Green was convicted by a jury in April and sentenced Friday evening by Judge Charles Bleil. He must serve 25 years in prison before he is eligible for parole.

The crime occurred in 2004 when Green grabbed the woman as she left an auto parts store in Pantego. He then forced her into her car, shoved a gun to her side and got behind the wheel.

The woman offered Green her car and purse, but he said he "just wanted a ride." Instead he drove her around and asked her personal information before covering her eyes with a wool cap. He then pulled over and raped her at gunpoint.

Green released the woman in East Fort Worth, telling her, "Don't let this affect your life," and she drove herself to an Arlington hospital.

Eight years after the rape, Pantego police identified Green as the assailant based on DNA evidence collected from the victim the day she was raped. She then picked Green out of a photo lineup.

At trial, prosecutors presented evidence that Green committed other sex offenses, including the molestation of a child under the age of 13, which he confessed to.

Green testified in his own defense and denied committing other offenses. He blamed the 2004 rape on his heavy drug use at the time.

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DNA ties 2004 rape to Arlington man who told victim, 'Don't let this affect your life'

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Liquid DNA behind virus attacks

Posted: at 3:43 pm

PUBLIC RELEASE DATE:

6-Oct-2014

Contact: Alex Evilevitch alex.evilevitch@biochemistry.lu.se 412-482-2301 Lund University @lunduniversity

Viruses can convert their DNA from solid to fluid form, which explains how viruses manage to eject DNA into the cells of their victims. This has been shown in two new studies carried out by Lund University in Sweden.

Both research studies are about the same discovery made for two different viruses, namely that viruses can convert their DNA to liquid form at the moment of infection. Thanks to this conversion, the virus can more easily transfer its DNA into the cells of its victim, which thus become infected. One of the studies investigated the herpes virus, which infects humans.

"Our results explain the mechanism behind herpes infection by showing how the DNA of the virus enters the cell", said Alex Evilevitch, a researcher in biochemistry and biophysics at Lund University and Carnegie Mellon University.

Evilevitch stated that the discovery was surprising. No one was previously aware of the 'phase transition' from solid to fluid form in virus DNA. The phase transition for the studied herpes virus is temperature-dependent and takes place at 37C, which is a direct adaptation to human body temperature. Evilevitch hopes that the research findings will lead to a new type of medicine that targets the phase transition for virus DNA, which could then reduce the infection capability and limit the spread of the virus.

"A drug of this type affects the physical properties of the virus's DNA, which means that the drug can resist the virus's mutations", said Alex Evilevitch.

The second study that Evilevitch and his colleagues have published recently is about bacteriophages, i.e. viruses that infect bacteria, in this case E coli bacteria in the human gastrointestinal tract. The results show that this virus also has the ability to convert its DNA from solid to fluid form. As with the herpes virus, the phase transition takes place at 37C, i.e. adapted to human body temperature.

These two virus types, bacteriophages and the herpes virus, separated at an early stage in evolution, several billion years ago. The fact that they both demonstrate the same ability to convert their DNA in order to facilitate infection indicates that this could be a general mechanism found in many types of virus.

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Accused Murderer's DNA Found In Slain West Hartford Bank Teller's Car

Posted: at 3:43 pm

HARTFORD -- DNA from accused murderer Carl "Hood" Small was found in the SUV of slain bank teller Christopher Donato, a forensic scientist testified Monday.

Nicholas Yang, a forensic science examiner at the state police crime lab, said Small is a contributor to the DNA found in blood on the SUV's steering wheel and driver's side door. The SUV was missing when Donato was found fatally stabbed in his Prospect Street apartment on June 18, 2012. It was later found near a Vine Street apartment where Small, of Bloomfield, used to stay.

Monday was the fourth day of testimony. Young was one of a long line of forensic scientists to testify in Superior Court about evidence found in Donato's apartment, the SUV and in the Vine Street apartment.

Yang also testified that Small cannot be eliminated as a possible contributor to DNA found on the handle of a mop that police said was used in an attempt to clean up the bloody scene.

But Yang said there was insufficient information to conclude that Small's DNA was on other items gathered during the investigation, such as the knife that police believe is the murder weapon.

Check back for more information about the Monday's testimony.

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Accused Murderer's DNA Found In Slain West Hartford Bank Teller's Car

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Videos of Sasquatch Released By The Genome Project – Video

Posted: at 3:43 pm


Videos of Sasquatch Released By The Genome Project
These videos are property of Adrian Erickson, never before seen prior to this news broadcast.

By: The Bigfoot Project

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Number of genes linked to height revealed by study

Posted: at 3:43 pm

The largest genome-wide association study (GWAS) to date, involving more than 300 institutions and more than 250,000 subjects, roughly doubles the number of known gene regions influencing height to more than 400. The study, from the international Genetic Investigation of Anthropometric Traits (GIANT) Consortium, provides a better glimpse at the biology of height and offers a model for investigating traits and diseases caused by many common gene changes acting together.

Findings were published online October 5 by Nature Genetics.

"Height is almost completely determined by genetics, but our earlier studies were only able to explain about 10 percent of this genetic influence," says Joel Hirschhorn, MD, PhD, of Boston Children's Hospital and the Broad Institute of MIT and Harvard, leader of the GIANT Consortium and co-senior investigator on the study. "Now, by doubling the number of people in our study, we have a much more complete picture of how common genetic variants affect height -- how many of them there are and how much they contribute."

The GIANT investigators, numbering in the hundreds, shared and analyzed data from the genomes of 253,288 people. They checked about two million common genetic variants (those that showed up in at least 5 percent of their subjects). From this pool, they pinned down 697 (in 424 gene regions) as being related to height, the largest number to date associated with any trait or disease.

"We can now explain about 20 percent of the heritability of height, up from about 12 percent where we were before," says co-first author Tonu Esko, PhD, of Boston Children's Hospital, the Broad Institute and the University of Tartu (Estonia).

"The study also narrows down the genomic regions that contain a substantial proportion of remaining variation -- to be discovered with even larger sample sizes," adds co-senior investigator Peter Visscher, PhD, of the University of Queensland, Australia.

Greater size, greater power

Height is a model trait for understanding how human genetics works -- especially for traits produced by not one gene, but many. Height is easy to measure, and an estimated 80 percent of variation in height is genetic.

Previous large-scale genome-wide association studies (GWAS) have indicated that a large number of genes influence height, and suggested that the majority of heritability comes from common genetic variants, not rare ones. Because sample sizes have not been large enough to draw definitive conclusions, the GIANT team built the largest sample to date.

"When you double the sample size and increase your statistical power, you can make new discoveries," says Hirschhorn. "Our results prioritize many genes and pathways as important in skeletal growth during childhood. Without a highly collaborative model, there's no way we could get this work done."

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Number of genes linked to height revealed by study

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Moisturizing newborns may help to prevent allergies later in life: study

Posted: at 3:43 pm

Applying moisturizer to a newborn babys skin could help prevent eczema and even food allergies later in life, possibly offering an inexpensive and easy way to combat a growing global problem, according to a recent study by a Japanese institute.

The small-scale study carried out by researchers at the Tokyo-based National Center for Child Health and Development suggests that regular lotion in the first few weeks of life helps keep a babys immune system intact.

The scientists divided 118 newborns into two groups of 59 each, applying an emollient a glycerine-based over-the-counter moisturizer to one group of babies for 32 weeks and no treatment to the other group.

As a result, 19 in the intervention group developed atopic dermatitis, also known as eczema, against 28 in the control group.

The study, which the researchers said was the first of its kind anywhere in the world, could show that moisturizing reduces the risk of developing eczema by 30 percent.

The institute said in a press release that emollient prevents skin from drying out and cracking, which exposes immune cells and allows irritants to get in.

This, in turn, boosts the bodys production of antibodies to combat the irritant, resulting in over-production.

It is this over-production of antibodies that produces the symptoms of an allergy.

The institute said babies suffering from eczema tend to display strong reactions to egg white, and thus can go on to be allergic to eggs in later life or develop other problems, such as asthma or sinus infections.

It was known before that dry skin would cause eczema. One of the achievements of this study is that we came up with clear figures for the probability of developing eczema, the centers spokesman, Toru Sato, said Friday.

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Eczema expert defended by parents

Posted: at 3:43 pm

Albie was so itchy, he wasnt sleeping, says Milli. I spent each night lying beside him, holding his little arms by his sides to stop him scratching and waking himself up. I was awake most of the night. I was covered in his pus. I was physically and emotionally exhausted. The family my partner, George, our daughters Bess, six, and Ursula, four was suffering.

Respite came thanks to Dr Richard Aron, a 74-year-old consultant dermatologist who practises in north London and South Africa. His therapeutic approach differs only slightly from conventional eczema treatment yet appears dramatically effective. Hes hardly a maverick, but has received a cool reception from the medical establishment.

Milli, whose home is in the Somerset village of Kingsbury Episcopi, says: Most NHS professionals said Albie might grow out of it, and to apply for disability allowance. I didnt want money. I wanted someone to fix my son.

Her GP referred her to a paediatrician, but the oral antibiotics, steroid cream and moisturisers prescribed had little effect. Milli, who was breastfeeding, cut allergens such as wheat and dairy from her diet and household irritants such as laundry softeners. Nothing helped.

It was then she discovered a Facebook community, Dr Aron Eczema Treatment Discussion Group, where parents were comparing joyful notes. Dr Aron, she learnt, specialised in treating atopic eczema. Hed helped 4,000 sufferers. Many parents posted photographs of their children before and during therapy: it looks as if those children have emerged, fresh, smooth, silky and new.

Desperation overcame her initial scepticism. An online consultation cost 80 (the only fee charged, notes Milli). She sent Dr Aron photographs and information; he sent a treatment plan. She paid 35 to a London chemist to make up his prescription.

I remember the day the postman brought that tub of cream, she says. We put it on at lunchtime. Dr Aron advised five applications daily at first. By bedtime, you could see it getting better. On day two, Albies face looked glowing. Now, seven months later, hes pretty much eczema-free.

And yet, says Milli: Every single NHS professional Ive told about it has reacted either with disinterest or scorn.

One expects toads blood at least, but Dr Arons approach uses only components that are conventionally prescribed for childhood eczema steroids, antibiotics and moisturiser. But his method of delivery is different, with all three ingredients contained in one topical mixture, and with the ratio individually tailored, according to the patients age, body mass and the severity of their condition.

Antibiotics are normally prescribed as a short course of tablets by the NHS, for cases where eczema is infected. Even if prescribed topically, it will rarely be for long periods because of fears over antibiotic resistance.

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Eczema expert defended by parents

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109.6 /$ (2 p.m.)

Posted: at 3:43 pm

Applying moisturizer to a newborn babys skin could help prevent eczema and even food allergies later in life, possibly offering an inexpensive and easy way to combat a growing global problem, according to a recent study by a Japanese institute.

The small-scale study carried out by researchers at the Tokyo-based National Center for Child Health and Development suggests that regular lotion in the first few weeks of life helps keep a babys immune system intact.

The scientists divided 118 newborns into two groups of 59 each, applying an emollient a glycerine-based over-the-counter moisturizer to one group of babies for 32 weeks and no treatment to the other group.

As a result, 19 in the intervention group developed atopic dermatitis, also known as eczema, against 28 in the control group.

The study, which the researchers said was the first of its kind anywhere in the world, could show that moisturizing reduces the risk of developing eczema by 30 percent.

The institute said in a press release that emollient prevents skin from drying out and cracking, which exposes immune cells and allows irritants to get in.

This, in turn, boosts the bodys production of antibodies to combat the irritant, resulting in over-production.

It is this over-production of antibodies that produces the symptoms of an allergy.

The institute said babies suffering from eczema tend to display strong reactions to egg white, and thus can go on to be allergic to eggs in later life or develop other problems, such as asthma or sinus infections.

It was known before that dry skin would cause eczema. One of the achievements of this study is that we came up with clear figures for the probability of developing eczema, the centers spokesman, Toru Sato, said Friday.

See more here:
109.6 /$ (2 p.m.)

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