Category Archives: Transhuman News

SOBREVIVIR AL INSTITUTO | John DNA
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SOBREVIVIR AL INSTITUTO | John DNA - Video

DNA: #39;Sinful Thoughts #39; of the Former Pak President, Pervez Musharraf
Former Pakistani President Pervez Musharraf might himself be mired in a slew of legal cases in Islamabad, but this doesn #39;t stop him from commenting on India and Kashmir.

By: Zee News

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DNA: 'Sinful Thoughts' of the Former Pak President, Pervez Musharraf - Video

DNA N00b l 1st Daytage
Hey guys what is going on its N00b here presenting my first ever Daytage, hope you guys enjoy the vid, make sure to like and comment and if your feeling AWESOME! make sure to hit that sub...

By: DNA N00b

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DNA N00b l 1st Daytage - Video

DNA evidence links an Oak Lawn man with a lengthy criminal history to the sexual abuse of a woman who was riding on a CTA Red Line train in 2012, Cook County prosecutors said Thursday.

Michael Robinson, 31, of the 4300 block of West 95th Place, was also charged in a similar incident with a woman on a Blue Line train last May, prosecutors charged.

Judge Maria Kuriakos Ciesil ordered Robinson held in lieu of $400,000 bail on 11 felony counts including aggravated criminal sexual abuse, aggravated battery in a public place and attempted robbery.

Semen recovered from the coat and backpack of the 2012 victim matched Robinson's DNA, said Assistant State's Attorney Colleen Rogers. That victim, 28, was riding the Red Line home from nursing school in January 2012 about 7:30 p.m. when Robinson, the only other passenger in that car, boxed her in so she couldn't move. He exposed himself and sexually abused her, Rogers said. He also allegedly demanded her cellphone and cash.

The woman immediately reported the incident, and police took her coat and backpack as evidence.

Prosecutors did not say why it took so long for the Illinois State Police crime lab to complete its testing, but the lab has a backlog of DNA cases.

In the May incident, the 26-year-old woman was riding a Blue Line train at 3:30 p.m. when Robinson, again the only other passenger on the car, exposed himself and sexually abused her, Rogers said.

The woman called 911 and reported what happened, she said, and the incident was captured on a CTA surveillance camera.

Robinson was held Tuesday by CTA security after he was identified from CTA fliers, police said. He was arrested in the 500 block of South Pulaski Road.

He has eight felony convictions for attempted aggravated robbery, retail theft, burglary and possession of a controlled substance, Rogers said. He was also convicted of four misdemeanor charges including public indecency in 2010, she said.

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Prosecutors: DNA links man to CTA train sex abuse in 2012

The proteins that drive DNA replication -- the force behind cellular growth and reproduction -- are some of the most complex machines on Earth. The multistep replication process involves hundreds of atomic-scale moving parts that rapidly interact and transform. Mapping that dense molecular machinery is one of the most promising and challenging frontiers in medicine and biology.

Now, scientists have pinpointed crucial steps in the beginning of the replication process, including surprising structural details about the enzyme that "unzips" and splits the DNA double helix so the two halves can serve as templates for DNA duplication.

The research combined electron microscopy, perfectly distilled proteins, and a method of chemical freezing to isolate specific moments at the start of replication. The study -- authored by scientists from the U.S. Department of Energy's Brookhaven National Laboratory, Stony Brook University, Cold Spring Harbor Laboratory, and Imperial College, London -- published on Oct. 15, 2014, in the journal Genes and Development.

"The genesis of the DNA-unwinding machinery is wonderfully complex and surprising," said study coauthor Huilin Li, a biologist at Brookhaven Lab and Stony Brook University. "Seeing this helicase enzyme prepare to surround and unwind the DNA at the molecular level helps us understand the most fundamental process of life and how that process might go wrong. Errors in copying DNA are found in certain cancers, and this work could one day help develop new treatment methods that stall or break dangerous runaway machinery."

The research picks up where two previous studies by Li and colleagues left off. They first determined the structure of the "Origin Recognition Complex" (ORC), a protein that identifies and attaches to specific DNA sites to initiate the entire replication process. The second study revealed how the ORC recruits, cracks open, and installs a crucial ring-shaped protein structure (Mcm2-7) that lies at the core of the helicase enzyme.

But DNA replication is a bi-directional process with two helicases moving in opposite directions. The key question, then, was how does a second helicase core get recruited and loaded onto the DNA in the opposite orientation of the first?

"To our surprise, we found an intermediate structure with one ORC binding two rings," said Brookhaven Lab biologist and lead author Jingchuan Sun. "This discovery suggests that a single ORC, rather than the commonly believed two-ORC system, loads both helicase rings."

One step further along, the researchers also determined the molecular architecture of the final double-ring structure left behind after the ORC leaves the system, offering a number of key biological insights.

"We now have clues to how that double-ring structure stably lingers until the cell enters the DNA-synthesis phase much later on in replication," said study coauthor Christian Speck of Imperial College, London. "This study revealed key regulatory principles that explain how the helicase activity is initially suppressed and then becomes reactivated to begin its work splitting the DNA."

Precision methods, close collaboration

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Key moment mapped in assembly of DNA-splitting molecular machine