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Category Archives: Transhuman News

BGI Tech and Hebei Agricultural University complete the genome sequencing of the jujube tree

Posted: October 30, 2014 at 2:44 pm

PUBLIC RELEASE DATE:

29-Oct-2014

Contact: Press Office huwen@genomics.cn BGI Shenzhen

October 27, 2014 Cambridge, MA and Hebei, China BGI Tech and Hebei Agricultural University jointly announced the complete, high quality sequencing of the Jujube genome. Jujube is the most economically important member of the Rhamnaceae family, and the Jujube genome is particularly difficult to sequence due the high level of heterozygosity and other complicating factors. It is the first time that a genome in the Rhamnaceae (Buckthorn) family has been sequenced. This study has been recently published in Nature Communications.

Jujube is a major commercial fruit with up to 30 million acres under cultivation close to that of apple and citrus and China accounts for 99% of the 6 million tons of dried fruit produced annually. Jujube has a much higher vitamin C content than other well-known vitamin C-rich fruits such as orange and kiwi fruit, and also high levels of nucleotides, polysaccharides and other important functional components. Furthermore, the jujube tree is highly resistant to salinity and drought, and grows well in sandy, alkaline and arid areas. Therefor, decoding the genome of the jujube tree will have great implications to exploit those important traits.

The Jujube genome has the highest degree of heterozygosity (1.9%) of plants sequenced to date using next generation sequencing (NGS). In addition, the very high density of simple sequence repeats and low GC content make the Jujube genome particularly challenging for whole genome sequencing and assembly. By using a combination of BAC-to-BAC sequencing and PCR-free whole genome sequencing, the researchers were able to successfully complete the high quality de novo sequencing of 98.6% of the estimated Jujube genome, identifying 32,808 genes.

"This study has accelerated the functional genomics research of the Jujube tree, and will facilitate the genetic improvement and selective breeding of Buckthorn fruit trees", said Professor Mengjun Liu, head of the research team, for Hebei Agricultural Unviersity. "This research not only shows the expertise of the team and the power of sequencing technology, but we also expect its future applications in bring more value and benefits in healthy food production."

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About Agricultural University of Hebei

Founded in 1902, Agricultural University of Hebei (AUH) is one of the main universities of Hebei province. Its five campuses are located in the cities of Baoding, Qinhuangdao, Huanghua and Dingzhou, covering the areas of more than 1.9 million square meters. Since 1989, the university has won 6 national awards and 163 provincial awards for its excellence in teaching and research, making it the top ranked university among all Chinese provincial universities, for ten years in a row. AUH has also ranked among the top 10 agricultural universities in China for decades.

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BGI Tech and Hebei Agricultural University complete the genome sequencing of the jujube tree

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Einstein-Montefiore investigators present aging research at Gerontological Society of America's Annual Scientific …

Posted: at 2:43 pm

PUBLIC RELEASE DATE:

30-Oct-2014

Contact: Kim Newman sciencenews@einstein.yu.edu 718-430-3101 Albert Einstein College of Medicine @EinsteinMed

October 30, 2014(BRONX, NY)Investigators at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center will present their latest aging research at the Gerontological Society of America's (GSA) 67th Annual Scientific Meeting. Topics include the identification of a genotype that can predict survival, risk factors for cognitive impairment and the cellular biology of aging. GSA 2014 will take place November 5-9, 2014 in Washington, D.C.

"Einstein-Montefiore has distinguished itself in a range of aging fields from basic biology to clinical diagnosis and treatment," said Joe Verghese, M.D., chief, division of geriatrics, department of medicine, and director of the Center for the Aging Brain and the division of cognitive and motor aging, department of neurology, at Einstein and Montefiore. "Our ongoing longitudinal studies, in particular the Einstein Aging Study and LonGenity, also link the bench and the bedside, improving our understanding of the aging process and driving discoveries that may potentially slow it."

Dr. Verghese will attend GSA 2014 and is available for interviews.

Einstein-Montefiore symposia presentations are:

1. High-density Lipoprotein Cholesterol Phenotype and Genotype Predict Survival in Individuals with Exceptional Longevity This study of 326 older women and 106 older men found that those who survived longest had both higher levels of "good" (HDL) cholesterol and a variant of the gene CETP that increase blood levels of HDL. Presented by Sofiya Milman, M.D. assistant professor of medicine, Einstein, and attending physician, endocrinology, Montefiore.

2. Hearing Impairment and Incident Frailty in Older Adults 2,000 individuals age 70 and older were analyzed to evaluate if hearing impairment is linked with frailty. Findings demonstrated that those with moderate or greater hearing impairment had a 61.3% increased risk of frailty compared with normal hearing individuals, indicating that hearing impairment is independently associated with frailty. Presented by Rebecca Kamil, Einstein medical student.

3. Alterations in Body Composition with Aging and Connections to Diseases and Mortality

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BEST BABY ECZEMA PRODUCTS – Video

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Adult eczema may be unrecognized risk factor for fracture, other injuries

Posted: at 2:43 pm

PUBLIC RELEASE DATE:

29-Oct-2014

Contact: Erin Elizabeth White ewhite@northwestern.edu 847-491-4888 The JAMA Network Journals @JAMA_current

Adults with eczema had a higher prevalence of fracture and bone or joint injury (FBJI), as well as other types of injury-causing limitations, in a nationally representative sample of patients with a history of the chronic inflammatory disorder that can cause skin itching and result in sleep disturbance, according to a study published online by JAMA Dermatology.

Patients with eczema have multiple risk factors for injury that can include sleep impairment, the use of sedating antihistamines and coexisting psychological illnesses. However, the risk of fracture and other injury-causing limitations in adults with eczema has been largely unexplored. Fractures are a public health issue and that burden is expected to increase in the coming decades as the population ages, according to background information in the study.

Nitin Garg, M.D., and Jonathan I. Silverberg, M.D., Ph.D., M.P.H., of Northwestern University, Chicago, examined the association of eczema with increased risk of injury in a nationally representative sample of 34,500 adults (ages 18 to 85 years) with a history of eczema over the past 12 months.

The prevalence of eczema was 7.2 percent and the prevalence of any injury-causing limitation was 2 percent. An FBJI was reported by 1.5 percent of adults, while other injury-causing limitation occurred in 0.6 percent of adults. In adults with eczema, the prevalence of injuries increased initially, peaked at ages 50 to 69 years, and then decreased substantially in patients 70 years or older.

Researchers found that adults with eczema and fatigue, daytime sleepiness or insomnia had higher rates of FBJI compared to adults with sleep symptoms and no eczema. Adults with both eczema and psychiatric and behavioral disorders (PBDs) also had higher rates of FBJI compared to those with eczema or PBDs alone.

"In conclusion, adult eczema is associated with an increased risk of injury, particularly FBJI, which is only partially related to the presence of sleep symptoms and PBDs. Taken together, these data suggest that adult eczema is a previously unrecognized risk factor for fracture and other injury, emphasizing the importance of developing safer and more effective clinical interventions for itch and sleep problems in eczema, as well as preventive measures for injury risk reduction in eczema. Future studies providing better measures of fracture risk are needed to confirm these associations," the study concludes.

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Adult eczema may be unrecognized risk factor for fracture, other injuries

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Eczema linked to bone fractures, injuries in new Northwestern study

Posted: at 2:43 pm

CHICAGO (WLS) --

Between seven and 10 percent of adults in the US have atopic dermatitis, more commonly known as eczema. And many of them have a moderate to severe form of the skin disorder.

"The chronic itch, similar to patients that have chronic pain, interferes with every aspect of their life," said Dr. Jonathan Silverberg, a Northwestern Medicine dermatologist.

Silverberg says when moisturizers and emollients don't soothe the skin, more aggressive treatment is prescribed, like topical or oral steroids, or sedating antihistamines.

"Many patients report this phenomenon that they're distracted because of their itch or because they're sleep deprived," Silverberg said.

But Silverberg says he's noticed a troubling trend and set out a year ago to study it more closely.

He says adults with eczema are at a greater risk of accidental injury, and it could be directly related to the side effects of their medications. Silverberg says sedatives cause fatigue, and steroids can lead to bone density problems.

"More and more as we see these patterns, I'm almost never using sedating antihistamines anymore," Silverberg said.

Silverberg says until better options are developed to treat eczema and itch, doctors need to advise patients to think about strategies to minimize falls and to avoid driving while using sedating antihistamines.

"If your eczema is not well-controlled and you're not sleeping well, that's a problem and we need to get better treatment for that," he said.

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Eczema linked to bone fractures, injuries in new Northwestern study

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Accident prone eczema patients

Posted: at 2:43 pm

PUBLIC RELEASE DATE:

29-Oct-2014

Contact: Erin White ewhite@northwestern.edu 847-491-4888 Northwestern University @northwesternu

CHICAGO --- Intense itching and dry, irritable skin aren't the only problems adults with eczema face. They are at greater risk of accidental bone fractures and other injuries, a new Northwestern Medicine study has found.

This is the first study to find adult eczema is a risk factor for fractures and other injuries.

The increased odds of accidental injury could be directly related to the side effects of steroids and sedating antihistamines commonly prescribed to treat the skin disorder or the under-treatment of severe cases, study authors suggest.

"Many eczema patients who are prescribed medication for itch are often given sedating antihistamines or steroids, but those medications may come at a price," said Jonathan I. Silverberg, M.D., senior author of the study. "Sedatives cause fatigue, and steroids can lead to bone density problems and osteoporosis."

Silverberg is an assistant professor of dermatology at Northwestern University Feinberg School of Medicine and an attending physician at Northwestern Memorial Hospital.

The study, published Oct. 29 in the journal JAMA Dermatology, validates what Silverberg sees regularly at the Northwestern Multidisciplinary Eczema Center.

"Last month three of my patients with eczema cancelled at the last minute because of injuries," Silverberg said. "One fell and almost got hit by a bus, another was hit by a car and then another missed her appointment because she was in a car accident. You can't make this stuff up."

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How SELFIES can help cure skin conditions

Posted: at 2:43 pm

Sending selfies to a dermatologist may be as good as visiting them in person Study compared people who sent selfies to their doctor with face-to-face care Little difference in the percentage of people whose problem cleared over a year Experts said an online system for treating skin problems may work just as well

By Madlen Davies for MailOnline

Published: 08:35 EST, 29 October 2014 | Updated: 09:19 EST, 29 October 2014

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Sending doctors a 'skin selfie' may help treat eczema just as well as going to a clinic in person

Selfies are often associated with self-obsessed celebrities and people who are just a little bit vain.

But they could help cure eczema and save visiting the clinic, according to new research.

Sending a doctor a 'skin selfie' may help clear the problem just as well as going in person, the study found.

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Psoriasis: my introduction – Video

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Psoriasis: my introduction
For the past 18 months, I #39;ve been living with psoriasis. But it #39;s not as scary as it sounds. I wanted to share my experiences with the online community to gi...

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Psoriasis en 4 a las 4 reto abrazopsoriasis – Video

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Psoriasis en 4 a las 4 reto abrazopsoriasis

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Da mundial de la Psoriasis: Posibles tratamientos – Video

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Da mundial de la Psoriasis: Posibles tratamientos

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