Page 300«..1020..299300301302..310320..»

Category Archives: Transhuman News

Tune In: The Art of the Videogame Soundtrack – Highbrow Magazine

Posted: June 11, 2022 at 1:03 am

Soundtracks are some of the most iconic tunes in pop culture. Think of the work of Danny Elfman or John Williams. Songs like the Star Wars theme are universally known, and all it takes is that first blasting note of the orchestra for the listener to imagine the yellow text crawling down from the top of the screen.

Impressive soundtracks like this have made a massive imprint on pop culture, becoming an integral part of how some of the most famous stories have been told. However, few would consider soundtracks as casual listening music.

Franchise fans may listen to the Jurassic Park opening, but these pieces are generally enjoyed as an accompaniment to the media for which they were created. Some films have pop music as significant parts of their soundtrack, such as Top Gun, with songs like Danger Zone and Take My Breath Away.

This has become a common trend lately, with films like the Guardians of the Galaxy franchise having their soundtracks composed mostly of licensed music -- however, unlike Top Gun, these songs werent made for the film.

Videogame music has also had its own massive influence on pop culture. Think of the instantly recognizable music from the first Super Mario Brothers, and the music from Sonic the Hedgehog's first level Green Hill Zone.

Music in videogames has come a long way since the sometimes abrasive, albeit unique, sound of chiptune melodies. With the capacity for digital storage ever expanding, games now have fully produced and professionally recorded music to accompany them. Modern games often get the same treatment films do with full orchestral scores.

This has led to some phenomenal music created specifically for games, music that really transcends its ties to videogames and stands on its own as enjoyable listening even for those who have little interest in the source material.

A recent soundtrack that comes to mind are the tracks created for the radio in CD Projekt REDs 2020 game Cyberpunk 2077. Often simplified to Cyberpunk, the game was a highly anticipated project based off of a tabletop role-playing game from 1988.

Part of the games soundtrack is composed of pop songs that have been created to be heard over the radio in game. When traveling in cars or just traversing around the world, players will hear fictional radio stations broadcasting music that was created specifically for the game.

As a means of building the world, the game features music created by a wide variety of artists. While many of the real-world artists are presented under fictional band names, some notable artists who created and or performed music for Cyberpunk are: Refused, Run The Jewels, A$AP Rocky and Grimes. Grimess music is presented under the fictional popstar Lizzy Wizzy, a character she voices in the game.

There are 31 songs, three volumes, of original radio music for Cyberpunk spanning genres, creating a wide variety of interesting songs. One standout -- Resist and Disorder by The Cartesian Duelists (real world artist: Rezodrone) -- blends electronic, hard rock and a driving industrial rhythm. The song feels heavy with an insanely catchy chorus that breaks up the sound before bringing it back down to the crunchy guitar riff that serves as the songs base.

Like most of the songs on the Cyberpunk radio, the lyrics dont feel constrained simply to the world of the game. Many of the punk and anti-corporate ideals expressed in the music seemn just as relevant to the real world, as they do the fictional sci-fi dystopia.

Someone who isnt necessarily a fan of the source material, could thoroughly enjoy, and connect with, this music. Music in Cyberpunk isnt held hostage to its medium. Most songs dont refer to videogames or make allusions to fictional slang or terminology. This doesnt stop the music from characterizing and building the game world in a believable way.

Arguably the greatest music in Cyberpunk is the music of the fictional band Samurai. Samurai is a key part of the story of Cyberpunk 2077, with one of the main characters, Johnny Silverhand (portrayed by Keanu Reeves), as a guitarist and lead singer of the group.

Samurais music is performed by real-world Swedish punk band Refused, and the songs are terrific. The Ballad of Buck Ravers is a punk song about a corporate office worker being pushed over the edge by mindless work that inevitably gets him nowhere. Never Fade Away is another song exploring the idea of love lost, but not forgotten. The song features a catchy chorus almost reminiscent of 80s classic rock, contrasting but still complementing the harder tone of the rest of the song.

Chippin in is a hard rock song that plays with the double meaning of the gambling term with the transhumanist ideas of microchips and cybernetic implants, which serve as a key theme in cyberpunk.

Cyberpunks radio music was made specifically as pop music, it was further from the traditional soundtrack in that sense; however, there are other games that emulate pop music as a part of their backing tracks and to great success.

Atlus Persona series has a long history of soundtracks, with the most recent entry into the series Persona 5 having some of the best music yet. Persona 5 has what would best be described as jazzy tunes with lyrics beautifully sung by the Japanese vocalist Lyn. Her vocals combined with the incredible combination of heavy bass lines, synth and string accents make for some tracks that are unforgettable.

The songs perfectly capture the vibe of a lounge singer in a smoky jazz bar. The silky vocals and catchy melody in a song like Last Surprise and Life Will Change are enjoyable, even for people who don't like videogames.

Being a fan of punk and hard rock myself, the soundtrack for a game like Persona 5 is hardly the kind of music I would identify with my general music tastes. However, this soundtracks quality transcends genre preferences altogether. While not every track is accessible as casual listening (it still is a soundtrack after all), there are an outstanding number of terrific tracks to choose from.

The Devil May Cry series is another franchise that blends pop elements into its backing tracks.

Devil May Cry has a heavy emphasis on hard rock -- relevant to the over-the-top action and character of its main protagonist, accented with electronic elements.

The songs that really steal the show in the Devil May Cry games are the battle tracks that play during combat encounters in the game. The fifth games battle tracks stand out as they achieve unique sounds from the songs in the rest of the franchise, as well as helping to provide insight into the characters they play for.

Devil Trigger is the battle theme for one of the games three protagonists Nero. Devil Trigger stands in stark contrast to the series norm with a sound that can almost be described as EDM. The song has an explosive, energetic attitude to it that matches the chaotic action associated with Neros fighting style.

The female vocalist gives the piece an overall pop feel; however, under the surface, a solid hard rock base accompanied with hard rock backup vocals is reminiscent of songs from earlier games in the franchise.

The best song from Devil May Cry 5 is Bury The Light, which is the battle track for longtime series antagonist Vergil, who was released as a playable character in conjunction with the special edition of the game in 2020. The song topped the Apple music soundtrack chart in september 2020 and ranked #7 of all September 2020 when it was released.

Bury the Light is an epic orchestral metal song. The song accents its heavy metal core with electronic and orchestral elements, such as its electric violin opening. The lyrics are sung by Victor Borba, and capture the character of Vergil, a man (half demon) on a quest for power that has gone too far to be stopped.

Narratives and themes aside, a lot of videogame music is all about fun. While theres an almost infinite supply of music that deserves to be recognized, that's an ambitious task for this article. However, I think the point stands that there is a lot of terrific art created around the world, much of it overlooked in the mainstream. If nothing else, I compel you to listen to something you normally wouldnt, videogame or not -- maybe youll find something new worth appreciating.

Author Bio:

Garrett Hartman is a contributing writer at Highbrow Magazine.

For Highbrow Magazine

Image Sources:

--Super Mario Bros. (Wikipedia, Creative Commons)

--Anna Hanks (Wikimedia, Creative Commons)

--Rice Digital (Wikipedia, Creative Commons)

The rest is here:
Tune In: The Art of the Videogame Soundtrack - Highbrow Magazine

Posted in Transhumanist | Comments Off on Tune In: The Art of the Videogame Soundtrack – Highbrow Magazine

It’s been 10 years since Prometheus, what can the reboot teach the Alien TV show? – TechRadar

Posted: at 1:03 am

It's now been five years since we had a new Alien movie, and precisely 10 years, to this day, since Prometheus teased a soft reboot of the franchise. Not a prequel by name, hence the Alien-less title to encourage newbies, it was where a film where director Ridley Scott, who returned to the franchise for the first time since the 1979 original, Scott set out to reclaim the series and dabble with the creature's beginnings.

For a while, it looked like it might be Scott's final act in the series, with District 9 creator Neill Blomkamp attached to make a new sequel (opens in new tab), but he eventually returned to the franchise and made 2017's Alien Covenant (opens in new tab), which is where the xenomorph story was left hanging. For now.

Disney's buyout of 20th Century Fox raised the question of whether we'd seen the last of the acid-blooded beastie. The answer arrived in the shape of two new Alien properties on the horizon. A movie from Don't Breathe director Fede Alvarez recently entered development along with an upcoming TV series from Fargo showrunner Noah Hawley. (opens in new tab)

With scripts for the latter currently being written, and the show set to drop next year on FX, where might this series go next? Taking inspiration from Scott's first rekindling of the epic saga, we dive into five ways Prometheus can inspire the Alien TV series, what it needs to take on board and how it can avoid death at the hands of a facehugger...

Love it or hate it, Prometheus makes it easier for newcomers to jump right into the franchise. As an Alien prequel with no explicit connections to the 1979 original film, it's simple enough to enjoy the story without having to ingest an entire Wikipedia.

The series could stand to model a little of its structure around this concept; not to get bogged down in dense mythology, but to borrow familiar visuals from the franchise. Fingers crossed this is the idea behind it, as FX chief John Landgraf has already dubbed it (opens in new tab): "an extension and reinvention of the franchise."

With Prometheus, Ridley Scott jumped to a time before Sigourney Weaver's Ellen Ripley to tell a new story. A fresh cast of characters living within the Alien world makes sense, especially as serialized episodic storytelling requires a different kind of structure. If the show were to do this, it would enable Hawley to craft an original tale instead of feeling beholden to existing characters.

Based on what's revealed so far it sounds as though this is likely to be the case. We already know it won't include Ripley or any of her contemporaries, a decision made by locating the show "70-odd years from now" in roughly the year 2090. It's interesting to note the approximate time frame Landgraf suggests, as it is right around the time Prometheus takes place in 2089-2093.

This hints at the fact we'll likely be introduced to a new leading cast with the potential to name-drop Prometheus, Covenant or Alien characters. Fingers crossed it's Jonesy the cat.

Prometheus offered us fleeting glances at Guy Pearce's Peter Weyland and his relationships with his android offspring David and his daughter, Meredith Vickers played by a pre-flattened Charlize Theron. We learn only a little of Weyland's desire to confront his maker. For the most part, we're with the crew of the Prometheus. Like the majority of the movies in the franchise, the cast we grow to know and love are regular people.

But the show could include more of the leadership angle, the faces behind the decisions that directly impact the people sent to the frontline and how the megacorporation came to do what it does. Aliens includes a boardroom of unsympathetic suits with little interest in Ripley's story, and in Alien 3 we meet the reprehensible Michael Weyland.

This disparity between Weyland-Yutani workers and the Corporation leadership will likely be explored. In [my show], youre also going to see the people who are sending them [to space], Hawley told Vanity Fair. So you will see what happens when the inequality were struggling with now isnt resolved. If we as a society cant figure out how to prop each other up and spread the wealth, then whats going to happen to us?"

Bearing in mind the series won't take place on spaceships in the far reaches of the universe, it sounds as if the leadership might be forced to confront the beasts they've desperately wished to weaponize for the entire franchise.

The notion of yet another Alien story throwing a crew into peril in the far reaches of space feels predictable, so why not relocate somewhere else?

An Alien 3 teaser prematurely promised an Alien film on Earth, but it wasn't until Alien vs. Predator: Requiem butchered the concept that the idea fizzled out. Prometheus shows brief moments on Earth before the bulk of the movie relocates to the moon LV-223. The show should commit to a new setting as a way to freshen up the mythology.

According to Landgraf, the show plans to breathe new life into the idea: "Setting it on Earth is really interesting. We have to think forward about the future of the planet in terms of the environment, governance, technology and create and design a version of the planet in the future.

Prometheus dabbled with creation. Human creation at the hands of the Engineers and the Xenomorph's creation at the hands of Michael Fassbender's corrupt android, David. Both instances confront concepts of identity through technology. So what further steps might the Weyland-Yutani Corporation take?

It's easy to assume nefarious schemes could be in the works. Alongside their weapons division whose pursuit of the creature fueled the entire cinematic franchise, their artificial intelligence division is another area

Hawley sounds like he's planning to include this, but in a different way than previously seen: "In the movies, we have this Weyland-Yutani Corporation, which is clearly also developing artificial intelligencebut what if there are other companies trying to look at immortality in a different way, with cyborg enhancements or transhuman downloads? Which of those technologies is going to win?"

Throw in that competitive element and the world of Alien expands considerably. Weyland-Yutani's rivals could force the series in a new direction, with the race to engineer a new technology and master eternal life almost certain to include some horrific scenarios.

The parting shot of Prometheus reveals the birth of a xenomorph ancestor, dubbed the deacon. Not exactly the same creature, it shares familiar traits with the iconic beast but we see it so briefly it left die-hard Alien fans desperate for more.

Ridley Scott deliberately chose not to include the xenomorph in Prometheus but immediately did an about face when audiences responded unfavorably. "We discovered from it that [the fans] were really frustrated," he said shortly before the release of Covenant. "They wanted to see more of the original [monster] and I thought he was definitely cooked. So I thought: Wow, OK, Im wrong."

We know the TV series will include the alien apparently it's the only recognisable character we can expect to see but in what capacity? Each movie to date has pushed the creature design, added a new twist to the life cycle and mythology. In addition to the deacon, Prometheus also birthed the trilobite, the octopus-like squid which Shaw extracts from her body.

With the Earth setting, an angle on Weyland-Yutani's leadership operations, a fresh take on technology, all signs point toward a new era for the franchise and fingers crossed? An even more terrifying iteration of the alien.

Read the rest here:
It's been 10 years since Prometheus, what can the reboot teach the Alien TV show? - TechRadar

Posted in Transhumanist | Comments Off on It’s been 10 years since Prometheus, what can the reboot teach the Alien TV show? – TechRadar

Wow! International Space Station and Boeing Starliner captured in the same incredible image – Space.com

Posted: at 1:01 am

Set phasers to stunned: A photographer on the ground spotted a spacecraft 250 miles (400 kilometers) overhead, just about to meet up with the International Space Station (ISS).

Szabolcs Nagy, a space station tracker and photographerin London, captured Boeing's Starliner just 650 feet (200 meters) from the orbiting complex as the uncrewed Orbital Flight Test 2 (OFT-2) made a historic docking on May 20.

"I was listening to the conversation between Mission Control and ISS crew whilst taking photos with my telescope in the garden," Nagy, who also created SpaceStationGuys.com (opens in new tab), told Space.com.

In photos: Boeing's Starliner OFT-2 mission in picturesLive updates: Starliner's OFT-2 mission

"It felt like no other ISS imaging session before," added Nagy, who enhanced his camera's view using a 14-inch Dobsonian telescope with manual tracking, along with a 3x Barlow lens to increase the system's focal length.

OFT-2 successfully met all major objectives as Starliner is seeking to ship astronauts to the space station on future flights. While the spacecraft's mission results are still being judged against metrics with NASA officials, indications so far point to a crew going aboard Starliner later in the year.

Nagy described his photography session as "a totally surreal experience, really." In the moment, he wasn't sure if the two vehicles could fit in a single field of view, but everything was bright enough and close enough to capture a few thousand frames of the encounter, he said.

As you can see below, this image wasn't the only one he produced during the mission. And in between photography sessions, he was uploading Starliner mission content on his YouTube channel (opens in new tab).

Geraint Jones, a professor and head of the Planetary Science Group at University College London, photographed the spacecraft and station during docking procedures from his location in Guildford, Surrey. Jones snapped his image (opens in new tab) with a handheld camera only an hour's drive southwest from where Nagy stood.

As for Nagy, he was back at his camera during the reentry of Starliner five days later, as the Boeing spacecraft zoomed through the atmosphere en route to a safe parachute landing atWhite Sands Space Harbor in New Mexico.

"Check out the full video of the event; it was spectacular," Nagy said on Twitter (opens in new tab) May 25, adding, "As I tweet, Starliner is deploying the heat shield. Sooo cool."

Follow Elizabeth Howell on Twitter@howellspace (opens in new tab). Follow uson Twitter@Spacedotcom (opens in new tab)and onFacebook (opens in new tab).

Originally posted here:
Wow! International Space Station and Boeing Starliner captured in the same incredible image - Space.com

Posted in Space Station | Comments Off on Wow! International Space Station and Boeing Starliner captured in the same incredible image – Space.com

Immerse yourself in life aboard the International Space Station at ‘The Infinite’ VR experience – GeekWire

Posted: at 1:01 am

Visitors to The Infinite walk around an exhibit space at the Tacoma Armory that contains a full-scale VR version of the International Space Station. In the foreground, Lesley Kilp and Kyle Byram are sitting down to watch a VR spacewalk. (GeekWire Photo / Alan Boyle)

TACOMA, Wash. One tour of the International Space Station is not enough, even if you do the tour in virtual reality.

I found that out when I explored The Infinite, a cleverly conceived VR presentation that draws upon more than 250 hours worth of 3-D video shot aboard (and outside) the space station over the course of nearly three years.

After months-long runs in Montreal and Houston, the show or exhibit or whatever you want to call it landed at the Tacoma Armory late last month and is open to visitors through July 31.

The best way to describe The Infinite is to call it an immersive experience an entertainment genre of relatively recent vintage that would also include the immersive Van Gogh exhibits that are making their way around the world. (One such exhibit recently wrapped up its Tacoma run, and another is still playing in Seattle.)

Even by the standards of immersive experience, The Infinite is in a class by itself.

People dont necessarily realize that this is the largest virtual-reality experience that has ever been created, in terms of size and in terms of capacity of people, Felix Lajeunesse, co-founder of Felix & Paul Studios and chief creative officer for The Infinite, told me after my first encounter with the experience. We can have up to 150 people sharing that collective experience at the same time, walking inside a 7,000-square-foot open space.

So what do they experience?

Imagine putting on a VR headset, walking through outer space with the Northern Lights above you, and floating right through the hull of the ISS to peek in on what the astronauts are doing. You might be gathering with the crew around their makeshift dinner table for a birthday party, or watching them get ready for a spacewalk, or looking over their shoulders as they gaze through the stations giant picture window while the Earth spins below.

Youre not just watching a movie. Its as if youre in the movie.

The VR system tracks your movements as you walk around a full-scale skeletal model of the space station thats peppered with glowing virtual spheres. When you push your hand through one of the spheres, the view morphs into a 3-D video scene. You can hear the dialogue between the astronauts, or off-camera commentary from an astronaut.

Its a bit like walking into a movie set, NASA astronaut Christina Koch says in one of the mini-scenes. She was talking about what its like to arrive at the International Space Station, but she just as well could have been talking about The Infinite.

The experience is organized into four chapters, focusing on adapting to the space environment, doing the work of space exploration, cooperating with international partners and looking ahead to the future. You have only about 35 minutes in all to explore the station, so theres no way you can plow through more than 60 3-D scenes during a single tour.

At the end of Chapter 4, a sparkly path directs you through the VR space to a lounge chair where you can sit down and watch the presentationspice de rsistance: a spacewalk filmed in 3-D last September by a camera mounted on the space stations robotic arm.

Jonathan Woods, executive producer at Time Studios, said the VR spacewalk fulfilled a years-long dream of his.

To watch those astronauts working in front of you, I have to say, was a moment that on at least two or three occasions moved me to tears, he told me. One, because of the magnitude of having played some small part in creating that. But also [because of] the power that this has to transform people and allow them to experience the Overview Effect without the tremendous cost of leaving the planet on a rocket.

The Infinite came about because Time Studios (the multimedia arm of Time magazine) and Felix & Paul Studios (a Montreal-based production company specializing in immersive entertainment) were both exploring the possibilities for doing VR on the space station.

Felix & Paul Studios had already been following astronauts through their on-the-ground training for a documentary series, while Time Studios had produced an Emmy-winning digital video series about NASA astronaut Scott Kellys record-setting year in space. In 2017, the two teams decided to join forces with NASA and PHI Studio to boldly go where no media project had gone before.

The project involved building a specialized kind of 360-degree camera that could withstand the rigors of spaceflight, persuading NASA to set aside a significant chunk of the stations precious crew time, and training the astronauts to serve as cinematographers, producers and actors in orbit.

The thing that makes me the most excited to this day is the fact that the astronauts brought a lot of their own creative contributions to the project, Lajeunesse said. For instance, in many circumstances, while we were filming inside the space station with them, they would let the camera roll after they finished recording what was scheduled to be recorded. A lot of the content that you see there was captured that way, in those completely genuine moments.

In one classic 3-D moment, Canadian astronaut David Saint-Jacques lets his running shoes float in zero-G toward the camera. (Try to catch a shoe and see what happens.) In another scene, NASA astronaut Anne McClain shows Christina Koch around her new quarters and gives a piece of zero-G advice: If you happen to kick something, I would say, turn around and see what you kicked.

The VR environment for The Infinite is structured in such a way that you should be able to avoid kicking something or someone. When strangers come within a range of about 12 feet, they materialize in your virtual space station as sparkly, Star Trek-like avatars with a glowing blue light in their chests. And you can always spot people in your own group as avatars with a golden light, no matter how far away they are.

If youre worried about your kid, you will always see your kid, Lajeunesse said.

Here are some tips to maximize your Infinite experience, based on my tours:

Woods said The Infinite came together at a fortunate moment in time, with the International Space Station at its peak. Its an open question whether a project like The Infinite could get done if its creators had to start from square one today.

With the experiences that Ive had working with the Russian space program, I do not believe that it would be tenable to begin a partnership right now, given the tensions between the two countries, Woods said.

At the same time, NASA is ramping up its Artemis program to send astronauts to the moon. Will that be the next frontier for immersive experiences? Are people already thinking about doing virtual-reality moonshots?

I can neither confirm nor deny, Woods said with a laugh.

Timed-entry reservations for The Infinite at the Tacoma Armory (presented by Tacoma Arts Live) can be made via the Fever online ticketing service. Ticket prices range from $15 to $48. Age requirement: 8 or older. The experience is wheelchair-accessible, and lasts about 60 minutes.

Want to bring the virtual space station into your home? The 3-D VR scenes from the station can be seen not only in The Infinite, but also in Space Explorers: The ISS Experience, an immersive series available for Oculus headsets.

See more here:
Immerse yourself in life aboard the International Space Station at 'The Infinite' VR experience - GeekWire

Posted in Space Station | Comments Off on Immerse yourself in life aboard the International Space Station at ‘The Infinite’ VR experience – GeekWire

Airbus sending 3D printer to space station next year to pave way for off-Earth factories – Space.com

Posted: at 1:01 am

European aerospace company Airbus will send a metal-crafting 3D printer to the International Space Station next year as a first step in its plans to set up an orbital satellite factory.

The printer, called Metal3D, can work with metals that melt at temperatures of up to 2,100 degrees Fahrenheit (1,200 degrees Celsius). It will be the first metal 3D printer on the space station, Airbus said in a statement (opens in new tab), and will enable astronauts to print parts such as radiation shields and various tools. (American company Made In Space, now a subsidiary of Redwire, has sent several 3D printers to the space station, but none of them can print metal.)

Future versions of the 3D printer, the company added, will be able to make objects using lunar soil and also recycle parts from old satellites.

Related: 3D printed satellite antennas can be made in space with help of sunlight

The Metal3D printer is only one component in a range of technologies developed by Airbus with the goal of setting up a space factory. In a series of videos, Airbus showed off a robotic manipulator designed to assemble spacecraft.

"Airbus' solution is to launch kit parts that will be assembled in space by the robotic arms from our space factory," the company said in the statement.

The robotic arms will be able to build each other in orbit, Airbus said, but could also be used to repair and refuel spacecraft.

The company said it would like to be able to manufacture entire satellites in space in the "next three to four years."

"Since there is enough space in space, it will be possible to build bigger structures such as huge reflectors, allowing telecom satellites to cover the entire planet," Airbus said in the statement.

Moreover, producing satellites in space will also be kinder to the environment, the company said, as fewer polluting rocket launches will be needed.

"The material for production can be sourced from the space debris floating around," Airbus said. "So with the space factory, Airbus is also helping to clean up space and ensure a sustainable future for the industry."

When it comes to the Metal3D printer, the space station is only its first destination. By the end of this decade, Airbus said, a similar device might be churning out parts of lunar rovers and habitats directly on the surface of the moon.

Follow Tereza Pultarova on Twitter @TerezaPultarova. Follow us on Twitter @Spacedotcom and on Facebook.

Excerpt from:
Airbus sending 3D printer to space station next year to pave way for off-Earth factories - Space.com

Posted in Space Station | Comments Off on Airbus sending 3D printer to space station next year to pave way for off-Earth factories – Space.com

Moon bricks, space sutures and more: Meet the science SpaceX is flying to the space station this week – Space.com

Posted: at 1:01 am

A lot of science gear will go up to the International Space Station this week on SpaceX's 25th cargo resupply service mission to the orbital lab.

The uncrewed flight, known as CRS-25, will kick off on Friday (June 10), when a Falcon 9 rocket launches a Dragon capsule from Florida's Cape Canaveral Space Force Station. The Dragon is packed with a variety of cargo and supplies, including a trove of science experiments.

Ranging broadly in their focus, the science headed to the International Space Station (ISS) includes investigations into immune system aging and recovery, global dust composition and its effect on the climate, how communities of microorganisms in soil are affected by microgravity, and more.

Related: Building the International Space Station (photos)

In a call with reporters on Thursday (June 2), NASA officials voiced excitement about the number of experiments headed to the orbital laboratory, as well as the increased ability of astronauts to conduct them.

For nearly a decade after the 2011 retirement of NASA's space shuttle fleet, the agency was dependent on Russian Soyuz spacecraft to carry its astronauts to and from the ISS. The three-person Soyuz is always commanded by a cosmonaut and therefore can carry a maximum of two spaceflyers to the U.S. section of the station.

But more people NASA, European and Japanese astronauts can get to and from the U.S. section now, thanks to the success of SpaceX's astronaut missions for NASA. The crewed version of Dragon is outfitted to carry four astronauts at a time, and SpaceX has now launched four operational crewed missions to the ISS.

And that boost in crew numbers has allowed greater research opportunities, NASA officials said.

"Since we've had four crew, and not too long ago five crew onboard ISS we've been flush with crew time," Kirt Costello, NASA's chief scientist for the ISS program, said during Thursday's briefing. "We've seen our ISS researcher sponsors respond and utilize all the time that's available."

Here's a rundown of some of the experiments headed to orbit next week. You can learn more about them and other research flying on CRS-25 via NASA here (opens in new tab).

The Earth Surface Mineral Dust Source Investigation, known as EMIT, will spend the next year measuring mineral composition of dust in Earth's driest landscapes. During Thursday's briefing, Robert Green, EMIT's principal investigator, explained what he referred to as the planet's "mineral dust cycle."

Dust blown into Earth's atmosphere by high desert winds travels thousands of miles. The mineral content of this atmospheric dust affects the interconnected global climate system, and the composition of these minerals is key to discovering how. Depending on the minerals present, for example, atmospheric dust will absorb and reflect sunlight in different ways, heating or cooling areas, affecting cloud formation and atmospheric chemistry. This type of dust can also serve as a rich nutrient deposit when it settles in the ocean or on land.

Right now, according to Green, there are only a total of 5,000 mineral samples from Earth's global dust cycle in scientists' hands. EMIT aims to leave that number in the dust. The EMIT module is loaded in Dragon's trunk on CRS-25, and it's the mission's largest payload. Once Dragon reaches the ISS, EMIT will be attached to the station's External Logistics Module 1, where it will spend the next year spectroscopically analyzing over a billion dust samples from across the planet. Scientists hope to use this data to update global systems models for things like weather prediction and climate research.

Climate change: causes and effects

NASA's Artemis program aims to establish a permanent human presence on and around the moon. However, the question of how to best build sustainable habitats from locally sourced resources remains unanswered. Building materials like steel and concrete are heavy and extremely cost-ineffective to launch to orbit, let alone the moon.

Students at Stanford University are investigating how microgravity affects the formation of a concrete alternative that mixes an organic compound with water and "in situ" resources, like lunar regolith or Martian dust, to create a biopolymer soil composite (BPC). Rather than utilizing a chemical reaction, heat or pressure, the compounds used in BPCs allow the mixture to dry with "about half the strength of Portland cement," according to Stanford student Jocelyn Huang Thai, one of the team leads for the Biopolymer Research for In-Situ Capabilities investigation.

This experiment will use a compound called bovine serum albumin (BSA) to create six bricks aboard the space station, each about 0.3 inches (7 millimeters) long. On Earth, BSA forms protein bridges connecting dirt particles during the drying process. Researchers hope to compare bricks mixed in space with counterparts made on Earth to determine the influence of microgravity on the drying process and protein bridge formation, and how that affects the density and strength of the bricks.

The European Space Agency (ESA) and the University of Florence in Italy are sending skin samples to the space station on CRS-25. But these aren't just small flakes in a test tube. A set of tissue chips, containers designed to store human cells for study in microgravity, will hold samples of human skin and blood vessels, ethically derived, which have been wounded and then sutured to study the mechanical forces of stitches on the healing process in microgravity.

It stands to reason that, as the pace of human spaceflight increases, someone at some point will be inadvertently injured. Monica Monici of the University of Florence, principal investigator of the Suture in Space study, highlighted the benefits of studying sutures in space during Thursday's call.

"Previous experiments on cell cultures and animal models have shown that wound closure is delayed in microgravity conditions," Monici explained. "Since evacuation time from space to Earth [on future missions] might be very long, the need for implementing trauma care and surgeries increases Wound healing should be regarded as a major problem for investigation since it is critical for crew survival."

Immunosenescence, the aging of immune cells, occurs at a higher rate in microgravity, and that aging can inhibit cells' ability to repair tissues. Like the sutures experiment, the Immunosenescence investigation also uses tissue chips, but this time to study immunocellular aging.

You know the phrase, "You're only as old as you feel?" Well, according to Sonja Schrepfer, principal investigator for the project, you're only as old as your immune system. "An aged immune system is not necessarily correlating with the age of the patient but rather with the status of the immune system," Schrepfer, a professor of surgery at the University of California San Francisco, said during Thursday's call.

Researchers for the project will get to observe these cells in flight and back on the ground, too. A similar experiment flew on a cargo mission in December of 2018, but its mission parameters did not plan for a return. Scientists will get to observe the immune tissue's reaction post-flight, after Immunosenescence samples are returned to Earth in September.

Follow us on Twitter @Spacedotcom (opens in new tab) or on Facebook (opens in new tab).

See more here:
Moon bricks, space sutures and more: Meet the science SpaceX is flying to the space station this week - Space.com

Posted in Space Station | Comments Off on Moon bricks, space sutures and more: Meet the science SpaceX is flying to the space station this week – Space.com

Russia Warns of Potentially Pathogenic Space Germs on ISS – Newsweek

Posted: at 1:01 am

A Russian scientist has expressed concerns that the country's planned space station could end up being contaminated with germs already on the International Space Station (ISS).

Russia's plans for its Russian Orbital Space Station (ROSS) are ongoing amid the country's continued invasion of Ukraine, which has been internationally condemned. One possible option for the creation of the ROSS station would be to use existing Russian modules attached to the ISS. These modules could be detached and then operated independently.

However, Oleg Orlov, director of the Institute of Biomedical Problems of the Russian Academy of Sciences (RAS), has reportedly said that creating the ROSS station in this way could lead to "potentially pathogenic bacteria" spreading through and destroying parts of the station, according to Russia's state-run TASS news agency.

During a Russian space council meeting, Orlov was cited by the RAS as saying: "The option of creating the ROSS using the ISS modules will lead to the transfer of the microbiota to the new modules [and] will accelerate the process of their biocontamination which will result in potentially pathogenic bacteria and technophiles participating in the process of the biodestruction of materials emerging at the ROSS."

Orlov added that germ contamination had interfered with space tech once before when equipment was damaged by microorganisms during a mission on Russia's former Mir space station.

"Cumulative results show that microorganisms in numbers exceeding normative requirements were detected in 65 [percent] of samples," Orlov added according to TASS, noting that the amount had been increasing. Germs reportedly included those from the staphylococcus and streptococcus groups.

Space agencies have measures in place to prevent microbial contamination in spaceNASA uses clean rooms that thoroughly clean payloads destined for the ISSbut research has shown that space stations can host bacteria and fungi that could harm astronauts and equipment.

It's unclear what Orlov's comments will mean for Russia's ROSS plans. Experts have told Newsweek in the past that they doubt Russia will be able to get its space station operational in the foreseeable future due in part to financial issues, suggesting that microbes could be the least of their concerns.

Still, Russia's space industry chief Dmitry Rogozin has repeatedly threatened that the country could stop participating in the ISS project in which it has been a major partner for decades, working alongside the U.S. and several other countries.

Amid an international backlash against the war in Ukraine, Rogozin said in April that a decision on whether or not to pull out of the ISS had already been made and that partners would be informed of that decision with a year's notice. The Russian government has committed to continue working on the ISS until 2024.

Continue reading here:
Russia Warns of Potentially Pathogenic Space Germs on ISS - Newsweek

Posted in Space Station | Comments Off on Russia Warns of Potentially Pathogenic Space Germs on ISS – Newsweek

Fungi Protein Heading to Space Station Aboard SpaceX to Test Viability as Astronaut Food – The Spoon

Posted: at 1:01 am

Back in 2012, researchers exploring the thermal springs of Yellowstone National Park happened upon a hearty new microbe called Fusarium strain flavolapis. Having survived the acidic volcano springs of Yellowstone meant the microbe, a fungus, might just survive in a challenging environment like outer space.

That was the theory, but researchers will soon know how Fusarium flavolapis performs 254 miles above earth as the fungi heads to the International Space Station aboard SpaceXs 25th cargo mission for NASA on Friday, June 10th. The fungi will go to space as part of NASAs EPSCoR (Established Program to Stimulate Competitive Research), under a project where Montana State University, BioServe Space Technologies,and a startup called Natures Fynd will test how it performs and see if it could be used as a source of food for astronauts.

The fungi, now better known by its commercial name of Fy, was initially isolated by Dr. Mark Kozubal under a research program funded by NASA and the National Science Foundation. Kozubal would go on to found Natures Fynd as part of an effort to commercialize Fy as a complete protein that could be used in plant-based meat and dairy substitutes. Earlier this year, Fy made its way to market as part of a series of consumer products that includes meatless breakfast sausage and dairy-free cream cheese

As Natures Fynd worked to develop Fy into new consumer-facing products, the company continued to work with NASA under their Small Business Technology Transfer (STTR) program, which had opened a call for microbial biomanufacturing technologies in space. Natures Fynd worked with researchers from Montana State University to build a bioreactor prototype that could grow FY in microgravity environments like the International Space Station (ISS). And earlier this year, Natures Fynd, MSU, and Bioserve Space Technology, a Center within the University of Colorado Bouldertechnologies, received a grant under NASAs EPSCoR to test the bioreactor in space.

One of the reasons Fy is so attractive as a potential food source for astronauts is its a source of complete protein, meaning it has all nine of the necessary amino acids humans need as part of their diet. Its also a source of net new protein, meaning unlike pea or animal protein it isnt simply a protein thats been converted from one source to another. In space, efficiency is the name of the game, and Fys ability to create protein without an intermediary makes it a promising new candidate to feed long-term space travelers. Starting this Friday, researchers will soon know whether Fy will live up to that promise.

This project is one of many being funded by NASA as part of its effort to develop sources of food for long-term space travel. Earlier this year, the space agency announced $1 million in prize money for Phase 2 of its Deep Space Food Challenge, a NASA Centennial challenge that aims to foster innovation around sustainable food production technologies or systems that require minimal resources and produce minimal waste. The space agency has also experimented with baking cookies and printing pizzas in microgravity environments.

Related

Read more:
Fungi Protein Heading to Space Station Aboard SpaceX to Test Viability as Astronaut Food - The Spoon

Posted in Space Station | Comments Off on Fungi Protein Heading to Space Station Aboard SpaceX to Test Viability as Astronaut Food – The Spoon

Take the leap: A conversation with UC alumna and NASA astronaut Jessica Meir – University of California

Posted: at 1:01 am

Jessica Meir had dreamed for decades about what it would be like to sail among the stars. And when she got her chance in 2019, the experience surpassed all of her expectations. This weekend, the UC San Diego alumna will return to the university to share the wonders of her journey to space as a NASA astronaut and offer words of wisdom to the Class of 2022 at All Campus Commencement on June 11.

Portrait of NASA Astronaut Jessica Meir in an Extravehicular Mobility Unit (spacesuit). Photo by Josh Valcarcel/NASA, September 2018.

In advance of her visit, we spoke with Meir about the potential for scientific breakthroughs without the influence of gravity; how her love for our planet exponentially grew after seeing the magnificent landscapes from above; her belief in the power of getting out of your comfort zone to achieve great heightsliterally; and how even astronaut training could not prepare her for the pandemic when she returned home in 2020.

Q. You believe in taking risks to achieve great things, even if it means facing failure along the way. Have there been moments of disappointment on your journey to becoming an astronaut?

A.I absolutely believe that it is necessary to take risks and push yourself slightly outside your comfort zonethat's when the great things happen. Perhaps my biggest failure was in trying to become an astronaut. I had first applied in 2009 when I was completing my doctoral studies at Scripps Institution of Oceanography. I made it all the way to the final round of about 40-50 people, but when I arrived for the interview, I saw I was surrounded by incredible people with remarkable resumes and extraordinary accomplishments. I thought, okay, I'm never going to get selected. When the calls went out that year, I was not among them. Knowing that I had come that close and it hadnt worked out really hurt.

It would have been quite easy at that point to just give up because I had my other career as a scientist that I loved. When the chance came four years later to apply again, I thought, maybe I shouldnt take that risk and put myself through the mental anguish. But if I hadn't put myself out there again and applied, I wouldn't be here today. I hope that I can show that you have to take risks and fail on the way to making your dreams come true.

Q. You embrace challenges with zeal. Is there anything that you fear?

A.As astronauts, we train for years in advance of space missions, so we are incredibly prepared for everything that comes our way. Even though I haven't had to respond to a real emergency scenario in the space environment, I have been through simulations so many times that it's almost like I have muscle memory. We also have thousands of people working in mission control who have designed all of these systems and help maintain them to keep us safe. That's the top priority of everything that we do here at NASA:safety.

The only thing that I've ever feared as an astronautand I've heard this from many other astronauts as wellis the fear of making a mistake. You are so fortunate to be the one in space, and there are so many people that are depending on you and have been involved in this whole process. You feel this huge responsibility because you don't want to let anyone down.

Meir observes a floating sphere of water formed by microgravity inside the International Space Station's Kibo laboratory module. Photo by NASA, February 9, 2020.

Q. What is something you learned about yourself while working at the International Space Station that you didnt expect?

A.Ive wanted to go to space since I was 5 years old. I thought I was prepared for what that might be like because I had contemplated it so much. What surprised me was that it was even more incredible than I ever imagined. When you're anticipating something, you often build it up and sometimes it becomes a disappointment later. Yet being in space surpassed all of my expectations. Just being up there, weightless and floating 24 hours a day, having the privilege of looking down at the earth below, it changes you as a person.

Q. Youve conducted thousands of experiments throughout your career. What is the most exciting part about conducting science in space?

A.If you think about it, we have one variable here on Earth that is always with us in any scientific system: gravity. It affects us all and everything around us. You can only imagine what might happen to those systems if you remove this omnipresent variable. That's what makes the science we do on the space station so exciting. From physiology and medical experiments to combustion experiments and cell biologyyou name it and we're doing it up there. With this variable removed, who knows what's going to happen? There are so many areas of potential for extraordinary findings that we can unravel when we're doing experiments in space.

Q. We are experiencing an echo pandemic right now with many impacted by mental health struggles. How do you maintain wellness when you face challenges?

A.Psychological wellbeing is a very important part of our job as astronauts and plays a big role in our selection as well. We have a number of teams working to support our mental health, especially when were on long-duration missions in an isolated environment that contains a lot of stressors. During space missions we receive care packages and have the chance to do regular video chats with family members once a week.

There are many parallels to what we go through as astronauts and what the whole world has experienced with the COVID-19 pandemic. I launched to the International Space Station in September2019 before the pandemic began, and I landed April2020. Coming back to a completely different planet was much more difficult for me to deal with than the isolation and confinement on the space station. We tried to share some of the lessons we learned while living in space, such as maintaining a consistent schedule, exercising regularly and making time to communicate with family members.

Meir conducts an experiment inside the Life Science Glovebox that compares the microgravity-exposed samples to magnetically levitated samples on Earth for insights into bone ailments such as osteoporosis. Photo by NASA, March 3, 2020.

Q. Youve explored the deep ocean and the edges of the universe. What are the connections, and what draws you to these environments?

A.There are absolutely connections between ocean sciences and space sciences. A key similarity is the need for a life support system. In the ocean, this may mean scuba diving or using a robotic submersible to carry us into the water. In space, we may do a space walk or use a robotic spacecraft to complete our explorations.

What draws me toward both pursuits is the spirit of explorationgoing a little bit further, taking a look around the corner to see what places we haven't gone before. I've always been drawn toward extreme physiology; my expertise is the physiology of animals living in extreme environments. That's easily connected to what we're doing here in space, except now I am the animal in the most extreme of environments.

Q. Did your worldview change after returning to Earth?

A.Ive always been an environmentalist, but I can say it now resonates even more loudly. Seeing Earth from above, you realize how special it is and how we need to protect it. I remember watching the gradient blues of the thin, tenuous band of the atmosphere. You can see it change from a darker blue at the surface, then it gets thinner and thinner with altitude. In no time at all, it has disappeared into the void and blackness of space. When you see that with your own eyes, this extraordinary palette of beauty and how connected all the landforms are, it is so utterly gorgeous and breathtaking.

Being in space also made me realize just how interconnected everything is. Looking down at the earth from the space station, you see contiguous land masses with no borders. And you realize that we're all in this together, from addressing the COVID-19 pandemic to taking care of our planet. Its a view that I really hope I can share with more people.

I also noticed it's really an innate characteristic of humans to focus on small, trivial matters right in front of us. Sometimes, we need to be reminded to take a step back and not focus so much attention on those little things. Space does that for you. I feel so incredibly fortunate to have gained that kind of perspective.

Originally posted here:
Take the leap: A conversation with UC alumna and NASA astronaut Jessica Meir - University of California

Posted in Space Station | Comments Off on Take the leap: A conversation with UC alumna and NASA astronaut Jessica Meir – University of California

Immatics and Editas join up to bring CRISPR to ‘gamma delta’ cell therapy – BioPharma Dive

Posted: June 9, 2022 at 4:55 am

Dive Brief:

Though small in scope, Immatics and Editas deal adds to a flurry of recent activity involving treatments that harness gamma delta T cells, rare white blood cells with unique tumor-fighting capabilities.

Unlike the T cells used in Novartis, Gilead and Bristol Myers Squibbs treatments, gamma delta cells have elements of both innate and adaptive immunity, which could enable them to generate a broader response against cancers. These cells also have key differences that make them less likely to trigger graft-versus-host disease, give them the potential to persist in the body for years, and to recognize a range of targets.

Those traits have already prompted drugmakers including Takeda, Johnson & Johnson, Bristol Myers and Regeneron to make investments. Clinical data presented at the American Society of Clinical Oncology has further elevated the profile of gamma delta cell therapy, as a treatment from Adicet Bio has shown early promise against non-Hodgkins lymphoma.

Immatics has already capitalized on the momentum, turning its alliance with Bristol Myers into a new, lucrative deal. Now Immatics is bringing gene editing tools in as well.

Genetic engineering is already part of many cell therapies, as CAR-T treatments involve modifications that help T cells recognize cancer. But CRISPR and other gene editing approaches could help do more. Allogene Therapeutics, for example, uses gene editing to make changes aimed at reducing the risk of graft-versus-host disease. Nkarta and CRISPR Therapeutics plan to give treatments involving natural killer cells, which share some similarities with gamma delta T cells, more tumor-killing punch.

Immatics and Editas appear to share a similar goal, saying in a statement that they want to make gamma delta cells with enhanced tumor recognition and destruction. Those potential benefits do come with added risk, however. U.S. regulators halted testing of Allogenes programs last year to investigate whether the gene editing involved in its treatment led to a chromosomal abnormality in a treated patient. Follow-up investigation exonerated Allogenes treatment, but the setback led to a lengthy delay.

For Editas, the deal adds to multiple other partnerships involving cell therapy. The company is already working with Bayer's Bluerock Therapeutics subsidiary on natural killer cell therapies for solid tumors, and with Bristol Myers on so-called alpha-beta T cell treatments.

See more here:
Immatics and Editas join up to bring CRISPR to 'gamma delta' cell therapy - BioPharma Dive

Posted in Genetic Engineering | Comments Off on Immatics and Editas join up to bring CRISPR to ‘gamma delta’ cell therapy – BioPharma Dive

Page 300«..1020..299300301302..310320..»