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Category Archives: Transhuman News

Century Therapeutics to Host Virtual Research and Development Day on June 13, 2022 – GlobeNewswire

Posted: June 11, 2022 at 2:05 am

PHILADELPHIA, June 06, 2022 (GLOBE NEWSWIRE) -- Century Therapeutics (NASDAQ: IPSC), an innovative biotechnology company developing induced pluripotent stem cell (iPSC)-derived cell therapies in immuno-oncology, today announced that it will host a virtual Research and Development (R&D) Day on Monday, June 13, 2022, from 4:30 PM to 6:00 PM ET.

The R&D Day will feature presentations from the Companys management team and Sheila Singh, M.D., Ph.D., Professor of Surgery and Biochemistry, Chief Pediatric Neurosurgeon at McMaster Childrens Hospital, the Division Head of Neurosurgery at Hamilton Health Sciences, and the inaugural Director of McMaster's new Cancer Research Centre. The event will focus on the Companys next-generation iPSC-based cell therapy platform technologies and includes a discussion on its strategy in GBM with CNTY-103.

For additional information on how to access the event, please visit the Events & Presentations section of Centurys website.

About Century TherapeuticsCentury Therapeutics (NASDAQ: IPSC) is harnessing the power of adult stem cells to develop curative cell therapy products for cancer that we believe will allow us to overcome the limitations of first-generation cell therapies. Our genetically engineered, iPSC-derived iNK and iT cell product candidates are designed to specifically target hematologic and solid tumor cancers. We are leveraging our expertise in cellular reprogramming, genetic engineering, and manufacturing to develop therapies with the potential to overcome many of the challenges inherent to cell therapy and provide a significant advantage over existing cell therapy technologies. We believe our commitment to developing off-the-shelf cell therapies will expand patient access and provide an unparalleled opportunity to advance the course of cancer care. For more information on Century Therapeutics please visit http://www.centurytx.com.

Century Therapeutics Forward-Looking StatementThis press release contains forward-looking statements within the meaning of, and made pursuant to the safe harbor provisions of, The Private Securities Litigation Reform Act of 1995. In some cases, you can identify forward-looking statements by terms such as may, might, will, should, expect, plan, aim, seek, anticipate, could, intend, target, project, contemplate, believe, estimate, predict, forecast, potential or continue or the negative of these terms or other similar expressions. These statements are not guarantees of future performance These risks and uncertainties are described more fully in the Risk Factors section of our most recent filings with the Securities and Exchange Commission and available at http://www.sec.gov. You should not rely on these forward-looking statements as predictions of future events. The events and circumstances reflected in our forward-looking statements may not be achieved or occur, and actual results could differ materially from those projected in the forward-looking statements. Except as required by applicable law, we do not plan to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise.

For More Information: Company: Elizabeth Krutoholow investor.relations@centurytx.comInvestors: Melissa Forst/Maghan Meyers century@argotpartners.comMedia: Joshua R. Mansbach century@argotpartners.com

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Tune Out and Drop In! The Brain Focuses on What Matters through Data Compression – Genetic Engineering & Biotechnology News

Posted: at 2:05 am

Our senses are constantly inundating the brain with multifarious information. The brain must therefore continuously tune out distractions to focus on what matters. Understanding how organisms represent the external world internally is a key question for neuroscientists, psychologists, and computer scientists, but the strategies and efficiencies of representing the world in the brain remains understudied.

A paper published on June 6, 2022, reports a study conducted on mice that claims sensory systems compress representations of the external world in the brain while preserving information. Through modeling dopamine neuron activity and behavior during a time-restricted decision-making task, the scientists demonstrate cognitive systems in the brain compress representations if overall rewards are preserved.

The study, published in the Nature Neuroscience article titled, Efficient coding of cognitive variables underlies dopamine responses and choice behavior resulted from a collaboration of scientists from the neuroscience program at the Champalimaud Foundation in Lisbon, Portugal, the department of electrical and computer engineering at the Carnegie Mellon University, and the Harvard Medical School, Boston.

Joe Paton, PhD, director of the Champalimaud Neuroscience Research Program, is a senior author of the study [Alexandre Azinheira]Our goal was to try and understand the form of internal of cognitive representations in the brain. The world as you see it is a construction that your brain actively creates. We were trying to understand what this construction looks like and whether its form could help us to derive general principles by which the brain constructs our internal sense of the world, said co-senior author of the study, Joe Paton, PhD, director of the Champalimaud Neuroscience Research Program.

Christian Machens, PhD, head of the theoretical neuroscience lab at the Champalimaud Foundation, is a co-senior author of the study [Alexandre Azinheira].Another co-senior author of the study, Christian Machens, PhD, head of the theoretical neuroscience lab at the Champalimaud Foundation said, Compressing the representations of the external world is akin to eliminating all irrelevant information and adopting temporary tunnel vision of the situation.

The authors claim, these finding have broad implications in neuroscience and artificial intelligence (AI). Paton said, While the brain has clearly evolved to process information efficiently, AI algorithms often solve problems by brute force, using lots of data and parameters. Our work provides a set of principles to guide future studies on how internal representations of the world may support intelligent behavior in the context of biology and AI.

Lead author of the study, Asma Motiwala, PhD, said, By modelling dopamine neuron activity and behavior in a time-based decision making task, we reveal signatures of a core principle that may shape internal representations for behavior and cognition.

The researchers used a task where mice had to determine whether two tones were separated by an interval longer or shorter than 1.5 seconds to receive a reward, while the activity of their dopamine neurons were recorded. Machens said, Its well known that dopamine neurons play a key role in learning the value of actions. If the animal wrongly estimated the duration of the interval on a given trial, then the activity of these neurons would produce a prediction error that should help improve performance on future trials.

Midbrain dopamine neurons act like teaching signals in AI algorithms. Studying dopamine activity therefore offers a route to uncovering principles of information representation in neural circuits.

Paton explains, Imagine you wanted to know the formation of a football team on the field, but you only had access to a video of the crowd at the stadium. Because you know that the crowd tends to look at the ball, if you track where the crowd is looking, you can infer where the players are, and thus the teams formation. Now imagine you want to know the principles that coaches use to choose formations. You might be able to show that the formations used tend to maximize goals scored in relation to goals suffered, while at the same time minimizing the distance that players need to run.

Motiwala built different computational reinforcement learning models to test which model best captured both neuronal activity and animal behavior. The models shared common principles but differed in how they represented the information. The researchers found only models that compressed task representation could account for the data.

Machens said, The brain seems to eliminate all irrelevant information. Curiously, it also apparently gets rid of some relevant information, but not enough to take a real hit on how much reward the animal collects overall. It clearly knows how to succeed in this game.

The information represented captured variables of the task and the animals actions. Previous research has focused on the features of the environment independent of the individuals behavior. But we found that only compressed representations that depended on the animals actions fully explained the data, said Motiwala. Our study is the first to show that the way representations of the external world are learnt, especially taxing ones, may be dependent on and interact in unusual ways with how animals choose to act.

The team also found that a key behavioral signature of this interaction in their model and rats wasprocrastinationof a subset of challenging decisions.Paton said, When the mice were most uncertain about the correct choice, they tended to procrastinate in making their decision, until their limited representation of the task fooled them into thinking they were more likely to get the correct answer.

Paton believes, this work that helps clarify how the brain transforms the external world into internal representations, also provides a set of principles by which AI algorithms might profitably do the same.

Motiwala said, Our work shows an important set of interactions between actions and representations that may come about only during end-to-end trainingreward-based signals. This is likely to shed light not only on understanding how these networks operate, but open new perspectives with which we understand how neural representations may be learnt by different interacting brainsystems.

In their future studies, the scientists intend to investigate the representations of cognitive variables in other areas of the brain that drive dopamine neuron activity in this timing task, and extend the computational model to incorporate additional factors.

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Eczema on black skin: Pictures, symptoms, and treatment

Posted: at 2:03 am

Eczema causes patches of dry, inflamed skin. On skin of color, these patches may appear darker than the surrounding area, or have a grey, purple, pink or red hue.

Eczema is a common condition and can appear anywhere on the body. It can cause swelling, dryness, and skin discoloration. This skin discoloration will appear differently on different skin tones.

This article covers what eczema looks like on skin of color, as well as how to diagnose and treat it.

Eczema is an umbrella term that describes several common skin conditions.

These conditions include:

All forms of eczema can cause skin inflammation, dryness, and itchiness. People may have more than one type of eczema simultaneously.

Eczema tends to follow a relapsing-remitting pattern. This means that people can have periods where they experience no symptoms, followed by periods where the symptoms flare up.

Globally, atopic dermatitis is most common in Africa and Oceania.

In the United States, the prevalence of atopic dermatitis is 19.3% among African American children compared with 16.6% among European American children and 7.8% among children of Hispanic heritage.

The prevalence of eczema decreases with age. In the U.S., 7.3% of the adult population has a form of eczema that initially began under 2 years of age.

African American and Hispanic children are more likely to develop severe or persistent eczema. While genetics play a part in the formation of eczema, environmental factors also have an effect.

A 2018 review found that structural racial inequality in the U.S. is likely to affect atopic dermatitis severity in African American children.

Indigenous and Latinx children may also be at a higher risk of developing severe or recurrent eczema due to structural racial inequality.

Researchers have found that social inequalities mean that these children are more likely to be from lower-income households and disproportionately live in areas with higher pollution levels. These are risk factors for developing severe atopic dermatitis.

Racial inequality in healthcare is also a contributing factor.

Since eczema may be more difficult for some physicians to diagnose in darker skin types, some doctors may underdiagnose the severity of eczema in people of color.

This means that people of color can be more likely to develop more severe eczema than people with lighter skin.

Learn more about why eczema is more common among Black people.

On darker skin, eczema can cause darker brown, purple, or gray patches. The affected areas may be swollen, warm, itchy, dry, or scaly. After a flare-up, the affected skin may look darker or lighter than the surrounding area.

Eczema can appear anywhere on the body. However, Black people can be more prone to papular lesions, which look like small bumps on the torso, arms, and legs.

This is papular eczema, and it may resemble permanent goosebumps. Black people are also more likely to develop lesions on the extensor surfaces.

Extensor surfaces are the skin areas on and around a persons joints.

These bumps can develop around hair follicles, which is called follicular accentuation.

People of color may often experience extensive dryness and dark circles around their eyes due to eczema.

A dermatologist, a doctor who specializes in skin conditions, can diagnose eczema. However, eczema symptoms on darker skin can be different than on lighter skin. This can often lead to an underdiagnosis of eczema severity or misdiagnosis.

To diagnose eczema, a dermatologist will first examine physical symptoms and assess a persons medical history. They will also ask about any family history of eczema or associated conditions, such as asthma. They can help diagnose the type of eczema and recommend a treatment method.

Eczema is a chronic condition. However, it is possible to prevent or minimize flare-ups with the right management.

The Skin of Color Society offers the following advice to help manage eczema:

Many people find that certain things or situations can trigger a flare-up. Common triggers include:

Learn more about the causes of eczema flares.

Eczema refers to a group of common skin conditions that present differently in people of different skin tones.

The condition is most common in Africa and Oceania. In the U.S., eczema is most prevalent among African American children.

Systemic racial inequality means that African, Hispanic, and Indigenous Americans are more likely to have misdiagnosed, severe, or persistent eczema due to socioeconomic risk factors.

On darker skin, eczema patches may look dark brown, purple, or gray. In some cases, the condition presents small, firm, raised bumps.

Treatment and management are similar for all skin tones. Anyone experiencing the symptoms of eczema should see a doctor for diagnosis and treatment.

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Eczema on the Ears or Eyebrows: How to Cope – Everyday Health

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Gail Porter had recently gotten into the habit of leaving a pair of tiny costume jewelry earrings in her ears while she slept at night. They were flat, circular, and gold in color and the Los Angelesbased entertainment lawyer believed they were gold-filled, not gold-plated.

That distinction was important to her because she knew that gold-plated jewelry (which has only a thin layer of gold on the exterior that can flake off easily, exposing the base metal underneath) might irritate her skin.

When Porters earlobes became red, swollen, itchy, and hot to the touch, she decided that the earrings were probably gold-plated after all and that she was having an allergic reaction to the metal inside, possibly nickel or cobalt.

The outer parts of her ears broke out into an itchy, scaly rash, too, as did the creases behind her ears signs of the inflammatory skin condition atopic dermatitis.

Based on prior experience, Porter believes her allergic reaction to the earrings triggered the outbreak.

The most common form of eczema, atopic dermatitis is caused by an overactiveimmune systemthat produces inflammation and causes the skin barrier to become dried out and irritated, according to the National Eczema Association (NEA). The noncontagious condition is typically associated with dry, rash-like, itchy symptoms on the face, neck, arms, hands, feet, ankles, insides of the elbows, and backs of the knees.

But any area of the skin can develop atopic dermatitis, including the ears, says JiaDe Jeff Yu, MD, a dermatologist and the director of the Contact and Occupational Dermatology Clinic at Massachusetts General Hospital in Boston.

Indeed, he adds, the outside ear can be especially vulnerable to atopic dermatitis because it dries out easily, unlike some areas of the body where there are more oil and sweat glands, including the armpits, groin, and scalp.

Symptoms are similar to what would occur elsewhere on the body: Itching, scaling, and redness are by far the most common, says Dr. Yu. The rash can look purple, dark brown, or an ashy gray or white color on darker skin tones, according to the Asthma and Allergy Foundation of America.

The rash may hurt, says Yu, especially if scratching has led to open sores and a bacterial infection.

As Porter learned, atopic dermatitis can be triggered by allergic contact dermatitis when your skin has an allergic reaction to substances it touches. The metal in costume jewelry is a common cause, Yu says.

He adds that in-ear headphones, foam earplugs, and ear drops are other culprits, and the reaction can affect the ear canal.

Picking at or rubbing the skin in and around the ears can also trigger a flare-up. It is best to avoid scratching and rubbing these areas, says Peter Lio, MD, a Chicago-based dermatologist who is on the board and clinical advisory council of the NEA.

Like Yu, Dr. Lio points to dry skin as a possible cause. Very few people moisturize around the ears, and this may also help explain why eczema is more likely, he notes.

To minimize eczema flare-ups, Yu, who is also affiliated with the NEA, recommends the following:

Doctors can perform a so-called patch test on an area of skin to see if a particular substance might cause an allergic reaction that could trigger an atopic dermatitis flare-up.

Physicians can also treat atopic dermatitis involving the ears with topical medications that suppress the immune response, such as the following:

Treating atopic dermatitis in the ear area can be a challenge because the skin is delicate and sometimes hard to access, says Lio.

If [the eczema] is just below and behind the ear, usually creams or ointments can work well in those areas, Lio says. If there are cuts or fissures, it can be better to use a greasy ointment that is less likely to sting than a cream or gel or liquid. Things get more difficult if the ear canal itself has eczema: Then we often use oil-based [steroid] ear drops to help get a bit inside and cool the inflammation and itch.

As for nonprescription remedies, Gail Porter found that moisturizing her ears and face with an over-the-counter lotion that contained colloidal oatmeal brought relief. I just started rubbing it on my ears, behind them, and on my face. The eczemas pretty much almost gone now, she says.

Her advice to others who are prone to atopic dermatitis: Take your jewelry off every night. Dont shower in it. Dont sleep in it.

If you are experiencing itching, scaling, and color changes on or in your ears, the problem may not be atopic dermatitis. You may be dealing with seborrheic dermatitis, also known as scalp eczema because it is most commonly found on the skin atop the head.

Seborrheic dermatitis is a fancy term for dandruff. It can occur anywhere the skin is oil-rich, such as inside the ears and the ear canal. It less often involves the external ear, says Yu. The crease behind the ears and even the eyebrows can be affected.

Heat, sweating, and the trapping of sweat and oils can all be factors in a seborrheic dermatitis outbreak, Yu adds.

The underlying cause of seborrheic dermatitis may be a genus of yeast-like fungi on the skin known as Malassezia. It may be that theMalasseziaeats the increased sebum and then the immune system reacts to the overgrowth of the yeast on the skin, Lio says.

Yu uses several types of medication to treat seborrheic dermatitis. Generally, I try to reduce the Malassezia yeast with an [antifungal] cleanser of some sort, such as ketoconazole or ciclopirox. Then, I have patients use an anti-inflammatory topical preparation such as a corticosteroid, or a nonsteroidal agent such as a topical calcineurin inhibitor, Yu says.

Antifungal creams are a treatment option as well, according to Yu.

You can head off seborrheic dermatitis flare-ups by avoiding in-ear headphones in the summer and prophylactically [preventively] washing the skin with antidandruff shampoos, Yu advises.

Following a regular skincare routine can help keep seborrheic dermatitis symptoms at bay, according to the NEA, which recommends washing affected areas each day with a gentle, 2 percent zinc pyrithione cleanser (Head & Shoulders and Selsun Blue are over-the-counter examples), followed by a moisturizer.

Daily shampooing is acceptable for people with seborrheic dermatitis who have naturally straight hair, according to an article published by Brownskin.net, a website founded by the Penn Medicine dermatologist Susan C. Taylor, MD. Individuals who have curly, tightly coiled, or straightened hair that is more fragile, dry, and prone to breakage particularly Black women should wash once or twice weekly, as directed by a doctor.

Gail Porter, who is Black and also has occasional bouts of seborrheic dermatitis on the scalp and behind her ears, says keeping her hair washed once or more a week has helped eliminate flakes and itchiness in both areas.

To avoid problems in the creases behind her ears, she is careful to dry that area thoroughly after each shampoo. Dont allow it to stay damp, she cautions.

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What People With Eczema Need to Know About Self-Screening for Skin Cancer – National Eczema Association

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Articles

By Angela Ballard, RN

Published On: Jun 6, 2022

Last Updated On: Jun 6, 2022

According to the American Academy of Dermatology (AAD), rates of skin cancer are on the rise in the United States. The good news is that having eczema does not necessarily make you more likely to develop skin cancer. However, severe eczema especially when its actively flaring can sometimes make it harder to recognize the early warning signs of certain types of skin cancer. This means that if you have eczema, getting to know your own skin, doing regular screenings and following up with your dermatologist if you see anything unusual is particularly important.

Though skin cancer typically looks similar for people with and without eczema, said Dr. Benjamin Ungar, assistant professor of dermatology at Mount Sinai Medical Center, active eczema may hide skin cancers to some extent, obscuring the ability to detect them. This is particularly true for sun-exposed areas such as the face, neck and forearms.

Susan Tofte, assistant professor of dermatology at Oregon Health & Science University, added that skin cancers can sometimes be scaly, tender, ulcerate and bleed, much like severe eczema, so its important to relieve eczema-related inflammation as much as possible in order to effectively screen for skin cancer. But everyone, she says, should look for skin cancer regardless of whether they have eczema.

To help yourself screen for any irregularities, examine your skin regularly (monthly, as per the Skin Cancer Foundation) and look for anything thats different or suspicious. Self exams are the most practical way to find skin cancer early, says the American Academy of Dermatology, when its still highly treatable.

The challenge? You might need a couple mirrors and a loved one to help you. And, of course, if you notice anything thats new or changing, youll want to contact your care provider right away.

As a best practice, the Skin Cancer Foundation recommends you check everywhere for signs of skin cancer: under the hair on your scalp, toenails and fingernails, on both sides of your hands, on the tops and bottoms of your feet, and even around your anus and genitals.

Look for anything out of the ordinary to you, or thats evolved since your last self-check. If you see something that fits this profile, talk to a knowledgeable healthcare provider as soon as possible.

This is what to watch for:

Although skin cancer can often look similar regardless of skin tone, Dr. Ungar noted that individuals with darker skin are more likely to develop skin cancer on the palms of the hands and soles of the feet, as well as under toenails and fingernails, as opposed to on sun-exposed areas where skin cancer tends to appear on lighter skinned people (i.e. on the scalp, ears, face, neck, chest, shoulders, forearms, or lower legs.)

To help prevent skin cancer, Tofte reminds us to use sunscreen or sun protective clothing and hats, saying: Its just good practice for preventing damage from the sun which may lead to skin cancer. If you are at particular risk, such as if theres a history of skin cancer in your family member or you have naturally pale skin that burns easily (particularly with red hair and blue or green eyes), she recommends a professional skin cancer screening yearly. Want to learn more about what skin cancer can look like? The Skin Cancer Foundation and American Cancer Foundation have useful pictures. But remember, everyones skin looks different, if you see something concerning or atypical, even if it doesnt match skin cancer photos, get it checked by a professional. Finding and treating skin cancer early can save your life.

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How to protect children with eczema from scratching until they bleed – Channel NewsAsia

Posted: at 2:03 am

She tried seeing many doctors, including dermatologists, and when the solutions didnt work, Yong turned to alternative practices such as naturopathy, and Traditional Chinese Medicine (TCM). Shan Min got prescribed TCM herbs which were boiled and mixed into her meals.

When Shan Min started solids, all her meals were cooked from scratch and Yong made records of all the ingredients and everything her child ate.

At 11 months old, when Shan Min weaned off breast milk, Yong found milk alternatives and made healthy wholesome meals daily.

At night, I would sit down with an A4 folder and pore over the daily records what she ate and her skin condition each day. This way I could identify trends and spot potential allergens. Our goal was to formulate a list of safe foods that we knew for certain wouldnt cause her to itch, while meeting her nutritional needs.

LITTLE WARRIORS AN IDEA BORNOF DESPERATION

The only thing which stopped her daughter from scratching herself bloody was protective garments with mittens that did not have any embellishments, Velcro, zippers or buttons.

At wits end, Yong asked her husband to source for garments that could protect Shan Mins skin while keeping her comfortable in Singapores heat. The garments also needed to include padded mittens to stave off scratches from the babys nails.

Yongs mental health was hanging by a thread. At that time, I was struggling mentally and crying every night for the pain my children were going through.

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Autism, allergies and other diseases and disorders afflicted baby boomers, too – PolitiFact

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We accepted a challenge put forth by a recent Facebook post suggesting that children today suffer from more diseases than baby boomers did when they were kids.

"Baby boomers had measles, mumps and chicken pox," said a post shared in a group advocating for "vaccine rights." "Todays kids have SIDs, autism, seizures, allergies, diabetes, cancer, speech delay, colic, ear tubes, HFMD, eczema and RSV. Time to start researching why"

This post was flagged as part of Facebooks efforts to combat false news and misinformation on its News Feed. (Read more about our partnership with Facebook.)

Lets get to it.

Measles, mumps and chickenpox

Before measles vaccines became available in the United States in 1963, an estimated 3 to 4 million people caught the virus each year, according to the Centers for Disease Control and Prevention. Widespread use of a vaccine protecting against the measles virus has led to a greater than 99% reduction in cases compared with the pre-vaccine era, the CDC says.

Mumps is a similar case. Once a common childhood disease, caes decreased more than 99% after its vaccine program started in 1967.

Chickenpox was also once common in the United States. In the early 1990s, about 4 million people in the U.S. caught it each year. Now, fewer than 350,000 people get it annually. Thats because a chickenpox vaccine became available in the United States in 1995, drastically cutting the number of cases, hospitalizations and deaths.

Sudden Infant Death Syndrome (SIDS)

The term "sudden infant death syndrome" was first proposed in 1969, but its not a modern phenomenon, according to a book by a neuroscientist and a forensic pathologist about the past, present and future of SIDS. Today, SIDS refers to the death of a seemingly healthy infant younger than 1 who dies under inexplicable circumstances, even after an investigation and autopsy. Cases of sudden death of healthy infants have been recorded for thousands of years, the book says. Some academics cite as the example of an Old Testament story about an argument between two mothers, one of whom discovered her baby dead in the night.

Autism

Autism has been a diagnosis for decades, though its definition has changed over time, and it didnt feature in the Diagnostic and Statistical Manual of Mental Disorders, or DSM, a handbook used by clinicians to diagnose illnesses and disorders, until 1980.

Donald Triplett, born in 1933, was the first person diagnosed with autism, appearing in child psychiatrist Leo Kanners 1943 paper "Autistic Disturbances of Affective Contact" as "Case 1, Donald T."

Hans Asperger, a pediatrician at the University of Vienna, described numerous children he observed as "autistic" in 1938. Other cases elsewhere in the world went undetected. The Smithsonian describes a man from the mid-1800s who was considered an "idiot" in the parlance of the time but who today would likely be diagnosed with autism.

Autism is being diagnosed more today than in previous generations, but it wasnt foreign to the baby boomers.

Seizures

Anti-epiletic drugs, used to combat seizures, have been around since the early 1940s, when baby boomers (born between 1946 and 1964) started to come on the scene. But children were having seizures well before that. In England, for example, children were first admitted to a colony for people with epilepsy starting in 1909.

Child neurology is a relatively new medical specialty, according to a 2003 article in the journal Pediatric Research, but it "traces its origins to the Hippocratic descriptions of seizures and other neurologic conditions in children. Its true beginnings can be traced to the 1600s and 1700s with classical descriptions of chorea, hydrocephalus, spina bifida, and polio."

Allergies

In 1859, a doctor in England who suffered from what were then called "summer colds" seasonal sneezing, runny nose experimented on himself and discovered his symptoms were caused by pollen, according to a 2018 National Geographic article on the history of allergies.

Our understanding of allergies has changed over time, particularly in the early 1950s with the discovery of mast cells that are packed with different chemicals, such as histamine, which produce symptoms of an allergic reaction. But "allergies are not new," the article says. "Such reactions have been described in historical documents with asthma symptoms recorded in ancient China, Rome, Egypt and Greece."

Still, food allergy rates among children have risen in recent decades, the BBC reported, and some researchers suspect this is because of diet and pollution, among other factors.

Diabetes

Diabetes dates back to 1500 B.C., though instances of childhood Type 1 diabetes started increasing in multiple countries around the late 1950s. Type 2 diabetes, meanwhile, was previously unheard of in children and teenagers, according to Johns Hopkins Medicine but is increasingly being diagnosed in young people. Many public health experts say childhood obesity is the culprit.

Cancer

Cancer did not skip the baby boomer generation when they were children. There are well-documented accounts of cases in the 1940s.

According to the National Cancer Institute, incidence of childhood cancer has been rising slightly in recent decades. (Survival rates have also increased by 18 to 27%, depending on the age of affected children and teens, from the mid-1970s to the 2010s.)

Speech delay

Speech pathology as a field has grown over the years, but language delay is not a new condition. Before 1940, according to a 1990 dissertation on the development of speech pathology in the United States, nine states recognized speech delays legislatively, and in 1925, four universities had awarded 20 degrees to graduate students with theses focusing on the scientific aspects of speech.

"Speech and its defects have been treated or mistreated for centuries by a variety of professions," the paper says. "Records describing defective speech and its treatment have been traced back to the fifth century B.C."

Colic

Colic, or intense and frequent fussiness in infants, also isnt new. Opium was once used to treat excessive crying, and in the 1800s, it was an ingredient in a syrup used to quiet babies.

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Ear Tubes

Ear tubes, developed to relieve infection in the middle ear, were first used in the late 1890s and reinvented in the 1950s, the Virginian-Pilot reported.

In 2007, NPR warned that while about 500,000 children have ear tubes implanted surgically every year, experts think about one-third dont need them.

Hand, Foot and Mouth Disease (HFMD)

HFMD was first reported in New Zealand in 1957, and the first recognized outbreak happened in Singapore in 1970. Its a common and usually mild childhood illness.

Eczema

The term atopic dermatitis better known as eczema dates back to 1933, but "despite its recent introduction into our medical lexicon, historical precursors of atopic dermatitis date back to at least as early as 69-140 CE," according to a 2017 paper on its history. That was during the Roman Empire, well before baby boomers were born.

A 2003 study found that the rate of children who suffer eczema had tripled since the 1970s, though the reason was unclear, according to the Guardian. "Improvements in hygiene may mean that there are fewer chances for babies to develop immunity to the condition, and genetics, environment and diet may also be factors," the paper said.

Respiratory Syncytial Virus (RSV)

RSV, a common respiratory virus that can be dangerous for infants and older adults, was first discovered in 1956 "and has since been recognized as one of the most common causes of childhood illness," the CDC says. In the United States, hospitalization rates have risen during previous decades, according to a 2016 history of the disease.

Our ruling

This post wrongly suggests that baby boomers only suffered measles, mumps and chickenpox while children today endure a slew of new ailments. While cases of some of these diseases and disorders are more prevalent now than they were in children born in the 1940s to the mid-1960s, these are not new illnesses.

Some people commenting on the post also connected the supposed new medical problems to vaccines, but theres no credible evidence to support that. Meanwhile, vaccines have reduced cases of measles, mumps and chickenpox among children today.

We rate this post Mostly False.

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Is saltwater good for the skin? What to know Beaufort South Carolina The Island News – The Island News

Posted: at 2:03 am

Saltwater may benefit the skin, although there is little scientific evidence to support its use in skin care.

Seawater may contain beneficial nutrients, such as magnesium, potassium, and zinc, and have antibacterial properties. Soaking in mineral salt water may help relieve some skin conditions, such as psoriasis.

Epsom salts are also high in magnesium, although it is unclear how much of this the skin absorbs.

According to a 2016 review, water from deep in the sea may benefit certain skin conditions, such as eczema.

The review defines deep sea water as coming from a depth of more than 200 meters (m). Water from this depth may have greater benefits than other types of water due to its purity and high nutrient content.

People with atopic eczema dermatitis syndrome (AEDS) may have mineral imbalances that include some toxic materials, such as mercury or lead. Deep sea water may help to restore the balance of essential minerals and reduce toxic minerals. Deep sea water does not get much light from the sun and contains little to no bacteria and less plant plankton, which means it retains many nutrients.

The same research found that treating people who had AEDS with deep seawater helped improve symptoms.

Research has found that deep sea water may help reduce allergic responses in the skin. Deep sea water reduced antibodies called immunoglobulin E (IgE) that cause an allergic reaction.

People should note that manufacturers remove salt to make it safe for consumption. This means that other properties in seawater are responsible for these benefits rather than salt.

Balneotherapy is a therapy that aims to treat certain medical conditions by bathing in thermal mineral waters. Balneotherapy includes bathing in natural saltwater sites such as the Dead Sea or adding sea salts to a bath.

Balneotherapy may help treat plaque psoriasis and provide benefits for people with psoriatic arthritis.

Saltwater may work as a mechanical exfoliant on the skin. Exfoliating the skin removes dead skin cells from the top layer of the skin. This may help prevent a buildup of dead skin cells, which can cause some types of acne. If people have blackheads, it is best they avoid scrubbing the skin.

Salt scrubs may not be suitable for every skin type or more delicate areas of skin, such as the face. If people are unsure about using a salt scrub, they can talk with a dermatologist.

Magnesium is an essential mineral for overall health. Magnesium may also help to benefit the skin, as it supports cell function and cell repair and helps activate vitamin D. Some reports indicate that topical magnesium may help to relieve inflammatory skin conditions.

According to a 2017 review, prolonged soaking in Epsom salts may increase magnesium levels. The review discussed a study in which 19 participants took 2-hour long Epsom salt baths for 7 days. The results found an increase in magnesium levels in the blood.

The review concluded that overall, the skin does not appear to absorb magnesium easily absorb through the skin and that oral supplementation may prove more effective.

However, the study has never appeared in a peer-reviewed journal.

There is little scientific research about incorporating saltwater into a skin care routine. If people are unsure whether saltwater will benefit their skin, they can consult with a dermatologist.

Anecdotal evidence suggests the following methods for using saltwater in skin care:

To make a saltwater solution, try the following:

Alternatively, people can look for skin care products that contain sea salt.

If using salt as an exfoliating scrub, the American Academy of Dermatology Association (AAD) recommends the following precautions:

SIDEBAR:

Sources: https://www.medicalnewstoday.com/articles/is-salt-water-good-for-your-skin?

How to safely exfoliate at home. (n.d.).https://www.aad.org/public/everyday-care/skin-care-secrets/routine/safely-exfoliate-at-home

How to treat different types of acne. (n.d.).https://www.aad.org/public/diseases/acne/diy/types-breakouts

Nani, S. Z., et al. (2016). Potential health benefits of deep sea water: A review.https://www.hindawi.com/journals/ecam/2016/6520475/

Grber, U., et al. (2017). Myth or reality transdermal magnesium?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579607/

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What’s trending? The most-read stories on APAC beauty market and consumer insights – CosmeticsDesign-Asia.com

Posted: at 2:02 am

Beauty category will play key role in driving APACs travel retail recovery

The beauty category is set to be one of the major growth drivers of Asia Pacifics travel retail industry as people once again undertake cross-border trips.

Travel retail, which has been a major sales channel for the beauty industry, was among the most severely impacted by the COVID-19 pandemic in the past two years.

For Delhi Duty Free Services (DDFS), perfume and cosmetics (P&C) surpassed all other categories in terms of growth for the month of April.

Demand is rising across Asia Pacific for health-focused products including silicone-free hair shampoo, but BASF believes their vast potential in silicone-free conditioners too.

The silicone-free hair care trend demand is driven by the emphasis on products that are good for health.

While silicone-free shampoos are becoming a dime a dozen, there is a lack of silicone-free hair conditioners in the market.

Singapore-based livestreaming outfit, MyBKKShop, believes live commerce holds abundant potential for South East Asias (SEA) beauty sector.

However, live commerce space in the region was still in its nascent stage and lacked many advancements that could potentially hinder its growth in the region.

For instance, there is a lack of an integrated system to help on the backend as a major hindrance as well as the lack of a sense of community which makes for a more vibrant landscape.

Renovatio Bioscience believes skin care innovation is moving towards the development of therapeutic treatments for serious skin conditions such as eczema or psoriasis.

While its products are marketed as anti-ageing solutions, they can also be used by people suffering from conditions such as eczema or psoriasis.

Moving forward, the firm will continue its therapeutic skin care research and treatments for skin conditions like dermatitis, eczema, psoriasis and acne.

Singaporean beauty company Porcelain has launched Ukyo Beauty, its first make-up line to tap into the post-pandemic clean and minimalist colour cosmetics trends.

The launch has been timely as consumers beauty routines have changed drastically over the COVID-19 pandemic, and there have been more demand formake-up that goes beyond skin deep.

Additionally, Ukyo taps into the clean beauty movement, which till now mostly focused on skin care products.

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What's trending? The most-read stories on APAC beauty market and consumer insights - CosmeticsDesign-Asia.com

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Canada to require a warning be printed on every cigarette – Coventry Live

Posted: at 2:02 am

Canada is poised to become the first country in the world to require that a warning be printed on every cigarette. The move builds on Canadas mandate to include graphic photo warnings on tobacco products packaging a policy that started an international trend when it was introduced two decades ago.

We need to address the concern that these messages may have lost their novelty, and to an extent we worry that they may have lost their impact as well, minister of mental health and addictions Carolyn Bennett said at a news conference on Friday. Adding health warnings on individual tobacco products will help ensure that these essential messages reach people, including the youth who often access cigarettes one at a time in social situations, sidestepping the information printed on a package.

A consultation period for the proposed change is set to begin on Saturday, and the government anticipates the changes coming into force in the latter half of 2023. While the exact messaging printed on cigarettes could change, Ms Bennett said the current proposal is: Poison in every puff.

She also revealed expanded warnings for cigarette packages that include a longer list of smokings health effects, including stomach cancer, colorectal cancer, diabetes, and peripheral vascular disease. Canada has required the photo warnings since the turn of the millennium, but the images have not been updated in a decade.

Rob Cunningham, senior policy analyst with the Canadian Cancer Society, said he hopes the warnings printed directly on cigarettes become popular internationally, just like the package warnings did.

This is going to set a world precedent, Mr Cunningham said, adding no other country has implemented such regulations. He is hopeful that the warning will make a real difference. Its a warning that you simply cannot ignore. Its going to reach every smoker, with every puff.

Smoking rates have been steadily falling over the years. The latest data from Statistics Canada (StatCan), released last month, shows 10% of Canadians reported smoking regularly. The government is seeking to cut that rate in half by 2035. StatCan noted that roughly 11% of Canadians 20 and older reported being current smokers, compared to just 4% of people aged 15 to 19.

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