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Category Archives: Transhuman News
MIT DNA Wizard Predicts How to Make Pyramids, Cubes, and More Out of DNA
Posted: December 7, 2014 at 5:44 pm
Technology doesn't exist yet to make his predicted 3D DNA wireframes, but he's validated his model on exotic 2D structures
When you're a super-intellect at the Massachusetts Institute of Technology (MIT) sometimes you don't really worry about what practical uses of your science experiment. Sometimes you just want to make something that looks cool.
I. Spicing Up the Double Helix
That seems to be the story with MIT's new DNA (deoxyribonucleic acid) "coasters". They're beautifully patterned, outlandish polymeric constructs. Oh there's the usual justification about potentially using the technology to create custom DNA scaffolds for novel drug targeting. But mostly they just look really incredibly awesome.
In nature, of course, DNA is most commonly found in the familiar double helix. Chromosomes are formed of incredibly long strands of DNA coiled around polarized proteins, which then further assemble into a tightly compacted, information dense structure. The genome is selectively uncoiled for processing.
In the past two decades scientists have toyed with the idea of more exotic DNA structures. Some of the early efforts have gone towards creating so-called "DNAzymes" (aka deoxyribozymes). While not thought to occur naturally, these synthetic enzymes can mimic the action of ribozymes and have potential in targeted killing of cancer cells. There's also been investigation into using different interesting DNA structures such as hairpin loops to create DNA computers.
To move beyond such simple tinkering, MIT Biological Engineering Professor Mark Bathe devised algorithms that take into account the associative behaviors of certain DNA microstructures and molecular weights of the chain. The algorithms start by predicting small ordered patterns that typically looked like squares, rhombuses, or other simple shapes. These shapes are then used to form the basis of larger molecules.
II. From 2D to 3D in No Time Flat
His model can predict a variety of coaster-like exotic cylindrical relatively flat DNA patterns, some of which can be validated with experiment.
The principal innovation was in recognizing that we can virtually cut these junctions apart only to reassemble them in silico to predict their 3-D structure. Predicting their 3-D structure in silico is central to diverse functional applications were pursuing, since ultimately it is 3-D structure that gives rise to function, not DNA sequence alone.
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MIT DNA Wizard Predicts How to Make Pyramids, Cubes, and More Out of DNA
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Viewing A Genome On A BlackBerry Passport – Video
Posted: at 5:43 pm
Viewing A Genome On A BlackBerry Passport
NantHealth CEO Patrick Soon-Shiong says his new app will let doctors view genomes on a secure phone. Subscribe to FORBES: http://www.youtube.com/forbes Check...
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Viewing A Genome On A BlackBerry Passport - Video
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Download Owning the Genome A Moral Analysis of DNA Patenting PDF – Video
Posted: at 5:43 pm
Download Owning the Genome A Moral Analysis of DNA Patenting PDF
Click to Download PDF Here: http://bit.ly/1yZxnF5.
By: Lewis Egan
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Download Owning the Genome A Moral Analysis of DNA Patenting PDF - Video
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Dr Francis Collins Human Genome Project videos DNA National Institute of Health Brent Holland Show – Video
Posted: at 5:43 pm
Dr Francis Collins Human Genome Project videos DNA National Institute of Health Brent Holland Show
http://www.stitcher.com/podcast/brent-holland-show Our guests inspire and educate through their own real life stories in their own words; many are true legendary historical figures in their...
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Dr Francis Collins Human Genome Project videos DNA National Institute of Health Brent Holland Show - Video
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December 5th – Brenna Hassett – Cosmic Genome Science Advent Calendar – Video
Posted: at 5:43 pm
December 5th - Brenna Hassett - Cosmic Genome Science Advent Calendar
Brenna Hassett tells you how new, actual science suggests The Paleo Diet is not a brilliant idea after all... Every day a new free science clip from the good people at Cosmic Genome. Head...
By: The Incomplete Map of the Cosmic Genome
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December 5th - Brenna Hassett - Cosmic Genome Science Advent Calendar - Video
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osu Tsunamaru – Daidai Genome Insane – Video
Posted: at 5:43 pm
osu Tsunamaru - Daidai Genome Insane
MOD:DT HD.
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osu Tsunamaru - Daidai Genome Insane - Video
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December 6th – Baba Brinkman & Dr Heather Berlin – Cosmic Genome Science Advent Calendar – Video
Posted: at 5:43 pm
December 6th - Baba Brinkman Dr Heather Berlin - Cosmic Genome Science Advent Calendar
As Baba Brinkman freestyle raps on the mean streets of Edinburgh, Dr Heather Berlin breaks down his brain function. Every day a new free science clip from the good people at Cosmic Genome....
By: The Incomplete Map of the Cosmic Genome
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December 6th - Baba Brinkman & Dr Heather Berlin - Cosmic Genome Science Advent Calendar - Video
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African Genome Project Highlights Migration History
Posted: at 5:43 pm
Scientists have been making rapid advances in studies of genetic variations in European and East Asian populations. Now, populations in Africa, the cradle of the human race, are getting the same treatment. The African Genome Variation Project set out to discover more about how variations in DNA can help in understanding patterns of disease, ultimately leading to better treatments. Working with other institutions, including partners throughout Africa, the Genome Variation Project has collected and analyzed genetic information from nearly 3,000 individuals representing the diversity of the African experience over many millennia.
Manjinder S. Sandhu of Britains Wellcome Trust Sanger Institute, senior author of an article on the project in the journal Nature, said in a telephone interview that DNA reveals traces of the movement of people who originated in Africa, migrated elsewhere, and returned. Its a mass population movement from out of Africa," Sandhu said. "Populations have returned over thousands of years and mixed with population groups. And you see vestiges of those signals in the human genomes of modern Africans today. For example, genetic characteristics of Eurasian people were found in todays West Africans. Sandhu said the Genome Variation Project might help explain why certain genetic variations make some people more likely than others to develop specific diseases. And ultimately, if we understand the biological processes underlying those diseases, we can start thinking about how we can develop new medicines, or use existing medicines, to help combat and control those diseases, he said. In a commentary also published in Nature, Raj Ramesar of the University of Cape Town said analyses of more African genomes would open a larger window into human diversity, evolution ... and disease susceptibility.
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Hair analysis program can help improve eczema – Video
Posted: at 5:43 pm
Hair analysis program can help improve eczema
http://www.kwangwellness.com Inner Light.mp3 Kevin MacLeod (incompetech.com) Sunshine ver 2.mp3 Kevin MacLeod (incompetech.com)
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Hair analysis program can help improve eczema - Video
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How to get rid of eczema (skin and scalp) part 1 pt 1 of 2 Natural Hair #naturalhair – Video
Posted: at 5:43 pm
How to get rid of eczema (skin and scalp) part 1 pt 1 of 2 Natural Hair #naturalhair
Growing my natural hair and embarking on body building has presented some problems... http://www.youtube.com/subscription_center?add_user=ThePlatinumrose My other channel: #39;Platinum Life #39;...
By: Platinum Rose
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How to get rid of eczema (skin and scalp) part 1 pt 1 of 2 Natural Hair #naturalhair - Video
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