Category Archives: Transhuman News

Designer Baby
Designer Baby. . . . .Children to Order: The Ethics of #39;Designer Babies #39; http://www.livescience.com/44087-designer-babies-ethics.html Mar 13, 2014 - Creating designer babies who are free from disease...

By: my touch Net

See more here:
Designer Baby - Video

IMAGE:The Journal of Interferon & Cytokine Research (JICR), led by Co-Editors-in-Chief Ganes C. Sen, PhD, Chairman, Department of Molecular Genetics, Cleveland Clinic Foundation, and Thomas A. Hamilton, PhD, Chairman, Department... view more

Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, January 13, 2015--Emerging data on the role of inflammation and the immune system in the development, growth, and spread of breast tumors have focused increased attention on the role cytokines such as interleukin and transforming growth factor- play in breast cancer initiation, protection, and metastasis. A comprehensive overview of this new knowledge and its potential to lead to novel therapeutic approaches is presented in a Review article in Journal of Interferon & Cytokine Research (JICR) from Mary Ann Liebert, Inc., publishers . The article is available free on the JICR website until February 13, 2015.

"The Role of Cytokines in Breast Cancer Development and Progression", coauthored by Marcella Esquivel-Velzquez and colleagues from Universidad Nacional Autnoma de Mxico (Mxico City) and Instituto Nacional de Salud Pblica (Morelos, Mexico), reviews the latest evidence to support a regulatory role for cytokines (proteins that mediate communication between cells of the immune system) in breast cancer and other cancer-related disorders. The article explores the link between cytokines, inflammation, and obesity, which is a significant risk factor for breast cancer. Other topics include the association between cytokines and blood vessel formation, breast cancer metastasis, immunosuppression and the ability of breast cancer cells to evade the immune system, and the potential role of cytokines as prognostic factors.

"This article provides a thorough discussion of the impact of inflammation and cytokine biology on many aspects of breast cancer and can serve as a helpful resource to find specific details regarding mechanisms and therapeutic potential," says Journal of Interferon & Cytokine Research Co-Editor-in-Chief Thomas A. Hamilton, PhD, Chairman, Department of Immunology, Cleveland Clinic Foundation.

###

About the Journal

Journal of Interferon & Cytokine Research (JICR) , led by Co-Editors-in-Chief Ganes C. Sen, PhD, Chairman, Department of Molecular Genetics, Cleveland Clinic Foundation, and Thomas A. Hamilton, PhD, Chairman, Department of Immunology, Cleveland Clinic Foundation, is an authoritative peer-reviewed journal published monthly online with Open Access options and in print that covers all aspects of interferons and cytokines from basic science to clinical applications. Journal of Interferon & Cytokine Research is an official journal of the International Cytokine & Interferon Society. Complete tables of content and a sample issue may be viewed on the JICR website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Viral Immunology, AIDS Research and Human Retroviruses, and DNA and Cell Biology. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

Read more here:
Do cytokines have a role in the initiation and progression of breast cancer?

IMAGE:AIDS Research and Human Retroviruses, published monthly in print and online, presents papers, reviews, and case studies documenting the latest developments and research advances in the molecular biology of HIV... view more

Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, January 13, 2014--A cure for HIV/AIDS is the ultimate goal of rapidly advancing research involving diverse and innovative approaches. A comprehensive collection of articles describing the broad scope and current status of this global effort is published in a special issue of AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers . The Special Issue on HIV Cure Research is available free on the AIDS Research and Human Retroviruses website.

In the Commentary "How to Cure AIDS: Feeling the Elephant", Guest Editor David Margolis, MD, University of North Carolina at Chapel Hill, states, "The breadth and diversity of reports found in the issue reflect the many domains of investigation that must be brought to bear to solve challenges of persistent HIV infection, and provide one of the critical missing tools needed to end the worldwide AIDS pandemic."

HIV latency, in which reservoirs of virus persist despite effective antiretroviral therapy and are able to hide from existing anti-HIV drugs and the body's immune defenses, is one of the greatest remaining challenges to achieving a cure. Guochun Jiang and Satya Dandekar, University of California, Davis, discuss the potential of one emerging "shock-and-kill" strategy to eradicate latent viral reservoirs in the Review article "Targeting NF-B Signaling with Protein Kinase C Agonists As an Emerging Strategy for Combating HIV Latency".

Zelda Euler and Galit Alter, Ragon Institute of Massachusetts General Hospital, MIT, and Harvard University (Cambridge, MA), present another latency reversal approach that uses "killer" monoclonal antibody-based drugs that can seek out and eliminate replication-competent HIV in combination with agents able to flush the virus out of its hiding places. The authors describe this novel strategy in the Review article "Exploring the Potential of Monoclonal Antibody Therapeutics for HIV-1 Eradication".

"The HIV research community is turning its attention to a goal that seemed unimaginable not so long ago, the development of a cure for HIV/AIDS," says Thomas Hope, PhD, Editor-in-Chief of AIDS Research and Human Retroviruses and Professor of Cell and Molecular Biology at Northwestern University, Feinberg School of Medicine, Chicago, IL. "To support that effort, we are focusing the first issue of 2015 on HIV cure related research and making the work available free to researchers and the public alike."

###

About the Journal

AIDS Research and Human Retroviruses , published monthly in print and online, presents papers, reviews, and case studies documenting the latest developments and research advances in the molecular biology of HIV and SIV and innovative approaches to HIV vaccine and therapeutic drug research, including the development of antiretroviral agents and immune-restorative therapies. The content also explores the molecular and cellular basis of HIV pathogenesis and HIV/HTLV epidemiology. The Journal features rapid publication of emerging sequence information and reports on clinical trials of emerging HIV therapies. Tables of content and a sample issue may be viewed on the AIDS Research and Human Retroviruses website.

Read more from the original source:
Progress toward an HIV cure highlighted in special issue of AIDS Research and Human Retroviruses