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Category Archives: Transhuman News

Manned commercial flights to space station on track for 2017

Posted: January 27, 2015 at 10:49 am

A Boeing CST-100 crew ferry craft blasts off atop an Atlas 5 rocket in this artist's concept. Boeing and SpaceX both expect to be ready for initial piloted test flights in 2017. NASA

Last Updated Jan 26, 2015 9:30 PM EST

NASA expects to spend some $5 billion underwriting development of commercial spacecraft built by Boeing and SpaceX to carry astronauts to and from the International Space Station, officials said Monday, ending sole reliance on the Russians for crew ferry flights and eventually lowering the average cost per seat to around $58 million.

Gwynne Shotwell, president and chief operating officer of Space Exploration Technologies, or SpaceX, said her company's upgraded Dragon V2 ferry craft should be ready for an initial unpiloted flight to the space station in late 2016 with the first crewed flight, likely carrying a SpaceX test pilot and a NASA astronaut, in early 2017.

John Elbon, vice president and general manager of Boeing Space Exploration, said his company's CST-100 spacecraft is expected to be ready for an uncrewed test flight in April 2017, followed by a crewed flight, with a Boeing pilot and a NASA astronaut, in the July 2017 timeframe.

Both companies must complete the crewed and uncrewed test flights before NASA certification, which will pave the way for the start of operational crew rotation and cargo delivery flights to the International Space Station later in 2017. Until then, NASA will continue to rely on Russia's Soyuz spacecraft to carry U.S. and partner crew members to the lab complex.

"Commercial crew is incredibly important to the space station, it's important to reduce the cost of transportation to low-Earth orbit so that NASA has within its budget the capability to develop means to explore beyond low-Earth orbit," Elbon said during a news conference at the Johnson Space Center in Houston. "And importantly, I think, it's beginning a whole new industry. ... We're making great progress on the program."

Said Shotwell: "Our crew Dragon leverages the cargo capability that we've been flying successfully to the International Space Station. However, we understand, and we've been told, that crew is clearly different. So there are a number of upgrades that we've been working for the past few years to assure that this crew version of Dragon is as reliable as it can possibly be. Ultimately, we plan for it to be the most reliable spaceship flying crew ever."

In the wake of the space shuttle's retirement, NASA started a competition to build a commercial crewed spacecraft, with the first in a series of contracts intended to encourage innovative designs for reliable, affordable transportation to and from low-Earth orbit.

Last September, NASA announced that Boeing had won a $4.2 billion Commercial Crew Transportation Capability (CCtCAP) contract to continue development of the company's CST-100 capsule while SpaceX would receive $2.6 billion to press ahead with work to perfect its futuristic Dragon crew craft.

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Manned commercial flights to space station on track for 2017

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SpaceX, Boeing on Track to Get Astronauts into Space by 2017

Posted: at 10:49 am

TIME Science space SpaceX, Boeing on Track to Get Astronauts into Space by 2017 The unmanned Falcon 9 rocket launched by SpaceX on a cargo resupply service mission to the International Space Station lifts off from the Cape Canaveral Air Force Station in Cape Canaveral, Fla. on Jan. 10, 2015. Mike BrownReuters Boeing's first unmanned test flight is scheduled for 2016

Boeing and SpaceX expect to be in a position to launch astronauts into space by 2017, NASA announced Monday.

At a press conference at Johnson Space Center in Houston, NASA said the two companies were on track to fly U.S. astronauts to the ISS within two years. Boeing and SpaceX have already completed some of the preliminary testing necessary to get vessels in orbit.

Its an incredible testament to American ingenuity and know-how, and an extraordinary validation of the vision we laid out just a few years ago as we prepared for the long-planned retirement of the space shuttle, said Charlie Bolden, NASA administrator, according to a press release.

The two companies were selected to build vessels under NASAs Commercial Crew Program, which will help the U.S. launch astronauts into low-earth orbit and get them to the International Space Station.

NASA retired its space shuttle program in 2011 and has been relying on Roscosmos, Russias space agency, to get astronauts into space ever sinceat a cost of $71 million per seat.

I dont ever want to write another check to Roscosmos after 2017, Bolden said Monday, according to NBC News. If we can make that date, Ill be a happy camper.

Boeing expects to conduct a crewless test flight in April 2017 and one with a test pilot by that July. SpaceX said Monday they will conduct a crewless flight in late 2016, and get a pilot in the air by early 2017. Eventually, the program is also expected to open a pathway to getting private citizens into space.

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SpaceX, Boeing on Track to Get Astronauts into Space by 2017

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Moon Colonization | Ray Jay Perreault

Posted: at 10:48 am

Moon Colonization

http://www.space.com/21588-how-moon-base-lunar-colony-works-infographic.html

This is a great article on moon colonization. It covers the reasons why a moon base can make sense and it is technically feasible. Surprisingly the moon provides most of the necessities to support life; except of course food. Surprisingly the soil is 42% oxygen.

Aside from materials to make rocket fuel the moon has a high concentration of Helium-3 which is a good source of fuel for nuclear fusion. H-3 is a non-radioactive fuel which could be a great long term reactor fuel source.

The materials mined on the moon would be sent into orbit using a dual rail system which fires the materials off a track a couple of mile long. Instead of rockets, electrical energy is used to accelerate the mass.

Im pointing this out, because this is precisely how my moon base is described in my SIMPOC series. The only major different is, my moon colony named Desert Beach has to be abandoned because 99.9997 % of the people on Earth are wiped out by a suspicious virus and the astronauts on the moon have to use their lifeboats to get home.

Incidentally the first book in the series is FREE.

Ray Jay Perreault

http://rayjayperreault.wordpress.com

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Nanoparticles that deliver oligonucleotide drugs into cells described in Nucleic Acid Therapeutics

Posted: at 10:48 am

IMAGE:Nucleic Acid Therapeutics is an authoritative, peer-reviewed journal published bimonthly in print and online that focuses on cutting-edge basic research, therapeutic applications, and drug development using nucleic acids... view more

Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, January 27, 2015--Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their effectiveness has been limited due to difficulty crossing the cell membrane. A new delivery approach based on cell-penetrating peptide nanoparticles can efficiently transport charge-neutral oligonucleotide analogs into cells, as reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Nucleic Acid Therapeutics website.

In the article, "Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides," Peter Jrver and coauthors, Cambridge Biomedical Campus (U.K.), Karolinska University Hospital (Huddinge, Sweden), Stockholm University (Sweden), Alexandria University (Egypt), and University of Oxford (U.K.), note that while delivery systems exist to facilitate cell entry of negatively charged oligonucleotide drugs, these approaches are not effective for charge-neutral oligonucleotide analogs. The authors describe lipid-functionalized peptides that form a complex with charge-neutral morpholino oligonucleotides, enabling them to cross into cells and retain their biological activity.

"The exploitation of phosphorodiamidate morpholinos represents an exciting approach to treating a number of therapeutic targets," says Executive Editor Graham C. Parker, PhD, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Children's Hospital of Michigan, Detroit, MI. "This paper suggests an intriguing but practical approach to solving the lack of a convenient non-covalent delivery system."

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Nucleic Acid Therapeutics is under the editorial leadership of Editor-in-Chief Bruce A. Sullenger, PhD, Duke Translational Research Institute, Duke University Medical Center, Durham, NC, and Executive Editor Graham C. Parker, PhD.

About the Journal

Nucleic Acid Therapeutics is an authoritative, peer-reviewed journal published bimonthly in print and online that focuses on cutting-edge basic research, therapeutic applications, and drug development using nucleic acids or related compounds to alter gene expression. Nucleic Acid Therapeutics is the official journal of the Oligonucleotide Therapeutics Society. Complete tables of content and a sample issue may be viewed on the Nucleic Acid Therapeutics website.

About the Society

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Nanoparticles that deliver oligonucleotide drugs into cells described in Nucleic Acid Therapeutics

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Modern languages show no trace of our African origins

Posted: at 10:48 am

The evolution of human culture is often compared to biological evolution, and its easy to see why: both involve variation across a population, transmission of units from one generation to the next, and factors that ensure the survival of some variants and the death of others. However, sometimes this comparison fails. Culture, for instance, can be transmitted horizontally between members of the same generation, but genes cant.

Little is known about whether human demographic history generates patterns in linguistic data that are similar to those found in genetic data, write the authors of a recent paper in PNAS. Both linguistic and geneticdata can be used to draw conclusions about human history, but it's vital to understand how the forces affecting them differ in order to be sure that the conclusions we're drawing are accurate.

By conducting a large-scale analysis on global genetic and linguistic data, the researchers found that languages sometimes behave in ways very unlike genetics. For instance, isolated languages have more, not less, diversity, and languages don't retain the echo of a migration out of Africaunlike our genomes.

To conduct the analysis, the researchers focused on phonemes, which are the smallest linguistic units of sound that can distinguish meaning. For instance, English uses p and b to distinguish between the words pat and bat, which meansp and b act as phonemes. Other languages may not use these particular sounds to distinguish wordsor they may make finer distinctions, basing meaning differences on subtle changes like whether or not a puff of air follows the p.

Every language has a certain number of phonemes, and these phoneme inventories differ in size from language to language. The researchers compared information on global phoneme inventories with data on global genetics and geographic location in order to isolate how phonemic and genetic units track each other.

Some of their results were intuitive. They found that populations with greater geographical distance between them also had larger genetic and phonemic differences. Languages that come from the same family (like French and Italian) could be expected to have similar phoneme inventories, but the finding held true even for geographically close but historically unrelated languages.

However, some of their results were not quite as intuitive. When populations migrate, genetic diversity goes down, because thegroup thatmoves takes alongonly a portion of the gene pool of their originalpopulation. Isolated groups of people, who have no opportunity to mingle with other groups, therefore have limited genetic diversity. Language, on the other hand, shows the opposite pattern: languages with lots of close neighbors seem to be influenced by these neighbors, leading to less phonemic diversity over time. Isolated languages, on the other hand, change over the generations to become more diverse.

The most surprising finding was that, unlike genetic data, the human migration out of Africa has not left traces on modern linguistic data. This contradicts previous work in the field suggesting that, as with genetics, language diversity declines with distance from Africa, as a result of populations breaking off and moving farther away. The authors of the newpaper suggest that language changes faster than genetics, and it's less determined by the size and characteristics of a migrating population, leading to markedly different patterns in phonemic and genetic data.

This is a very interesting and important addition to the field, not only because it uses such a large database and introduces (relatively) new methods to the field, but also because of its findings, says Dr. Dan Dediu, who researches linguistics and genetics at the Max Planck Institute for Psycholinguistics in Nijmegen, The Netherlands.If its main finding survives replication with other databases and methods, then its a very powerful confirmation of the idea that demographic processes are one of the main driving forces behind both linguistic and genetic diversity."

It also highlights the fact that language and genes have different properties, especially when it comes to small, isolated communities and contact between populations, he adds.

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Modern languages show no trace of our African origins

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5-2 DNA Replication – Video

Posted: at 10:47 am


5-2 DNA Replication

By: Patrick Murphy

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5-2 DNA Replication - Video

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AW | DNA musical 68 KS sur Solar – Video

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AW | DNA musical 68 KS sur Solar
DNA posey avec l #39;asm1 speakeasy (the best). Chane Youtube GFX RaGe Zippo : https://www.youtube.com/channel/UCsy135gh0VL-C52mfG8Zx7Q 1ere musique ...

By: RaGe Freddy

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AW | DNA musical 68 KS sur Solar - Video

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DNA sur AW – Video

Posted: at 10:47 am


DNA sur AW

By: gabriel ferraz

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DNA sur AW - Video

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Burning DNA Outro – Power Director 13 – Video

Posted: at 10:47 am


Burning DNA Outro - Power Director 13
Just a little outro with "Thanks For Watching" message and Hoopsno1 logo. Music from Kill Bill and scrolling Pure gaming DNA message also accompany this short outro. Hope you enjoy and please...

By: HOOPSNO1 PURE GAMING DNA

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Burning DNA Outro - Power Director 13 - Video

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Se que Activission devrais faire (DNA BOMB et 79-0) – Video

Posted: at 10:47 am


Se que Activission devrais faire (DNA BOMB et 79-0)
Salut tout le monde !!! Ont se retrouvent aujaurd #39;hui pour une DNA , ainsi q #39;un flawless de 79 killstreaks. Aimer commenter partage et surtout abonne-toi.

By: marco 1109

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Se que Activission devrais faire (DNA BOMB et 79-0) - Video

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