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Category Archives: Transhuman News

Gene variant associated with better aging, cognitive function, study finds

Posted: January 28, 2015 at 4:43 am

People who carry a gene variation associated with longevity have better brain cognition and are more resilient to aging, new research has found, paving the way for future treatments for brain aging and disease.

Using whole-brain analysis of healthy older adults, researchers at the University of California, San Francisco (UCSF) found that those who had the gene variation, a single copy of the KLOTHO allele, called KL-VS, had larger volumes in the right dorsolateral prefrontal cortex (rDLPFC) of their brains and therefore slightly better cognitive function.

KL-VS codes for a protein, called klotho, that circulates in the body and is present throughout the animal kingdom. Its long been known that klotho, which is produced in the kidneys and brain, regulates aging.

The rDLPFC region, which interacts with many other brain regions, is most known for its role in executive function, higher-level cognitive skills used to control and coordinate cognitive abilities and behaviors, such as attention, working memory, and decision-making.

This type of cognition is really important in sophisticated and very simple types of thinking, first author Jennifer Yokoyama, an assistant professor of neurology at UCSF told FoxNews.com.

The rDLPFC is very vulnerable to aging and tends to get smaller, leading to lower cognition, Yokoyama added.

What our data means in the bigger picture is that people who carry the genetic code, one in five people, that confers a decade of resilience against expected decline in executive function and size of that region, senior author Dr. Dena Dubal, an assistant professor of neurology at UCSF, told FoxNews.com.

The team also found that two copies of KL-VS, about three percent of people, was associated with a shorter lifespan, increased cardiovascular risk, worsened cognitive function, and a smaller rDLPFC.

The findings are one of the first showing the positive effect of a genetic variant on brain aging, researchers said, adding to their previously published research that found that boosting the level of KL-VS in mice lead to longer lifespan and increased brain function. With this understanding, scientists are one step closer to predicting healthy brain aging and treatment for diseases affecting rDLPFC, such as Alzheimers and Parkinsons.

The question we are answering next is what does this mean for [brain] disease and how can this be translated into some kind of therapeutic to help people suffering? Dubal said.

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Gene variant associated with better aging, cognitive function, study finds

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The Market for Personalized Gene Therapy Treatments for Cancer

Posted: at 4:43 am

DUBLIN, January 27, 2015 /PRNewswire/ --

Research and Markets (http://www.researchandmarkets.com/research/p54ckt/the_market_for) has announced the addition of the "The Market for Personalized Gene Therapy Treatments for Cancer" report to their offering.

(Logo: http://photos.prnewswire.com/prnh/20130307/600769 )

The Market for Personalized Gene Therapy Treatments for Cancer

This report, The Market for Personalized Gene Therapy Treatments For Cancer provides an exhaustive review of the market potential for relatively new approach in cancer research. It involves modification of genes instead of using a surgical method or chemical drug product. Essentially, gene therapies replace an abnormal gene with a normal gene, or changes the response of a gene (turn on or off). Not all of the approaches to gene therapy are the same, and different cancers appear to respond better to different therapies.

Several gene therapy technologies have the ability to work in combination with other treatment options to enhance the effectiveness of a therapeutic regimen. Gene therapy is also designed to target specific cells making treatment much less damaging to healthy cells.

This report discusses those treatments and estimates market size and market potential for personalized medicine using gene therapy. As part of its data offering, the report provides disease incidence, gene therapy product developments and market forecasts for the following types of cancer:

In addition the report provides:

Historically, cancer treatments have been very invasive and detrimental process to the body. However, there are numerous new techniques available for those with cancer that are not as invasive and detrimental to the body as a whole. These treatments range from the severely alternative to the more traditional. Newer alternative treatments are more precise and much less invasive as some of the traditional methods. Gene therapy is the most prominent new form of these alternative treatments. It is being studied as a way to change how a cell functions, for example, by stimulating the cells of the immune system to attack cancer cells.

Companies discussed in this report include those which have registered trials in Phase I through Phase III development and have promising development activities.

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The Market for Personalized Gene Therapy Treatments for Cancer

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Censorship///CLIMAX SEX DANCE – Video

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Censorship///CLIMAX SEX DANCE
Censorship. https://m.facebook.com/profile.php?id=1511359092424129.

By: analu78

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Censorship///CLIMAX SEX DANCE - Video

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Censorship/// YOU ARE LOVED BY ME – Video

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Censorship/// YOU ARE LOVED BY ME
https://m.facebook.com/profile.php?id=1511359092424129.

By: analu78

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Censorship/// YOU ARE LOVED BY ME - Video

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Art Censorship – Adult Beginner and Intermediate Tap – Spring 2014 – Video

Posted: at 4:43 am


Art Censorship - Adult Beginner and Intermediate Tap - Spring 2014
Music: "Patterns" by Danny Elfman Show Theme: Music Icons Fun Fact: This dance is about art censorship. The rhythm tappers represent artist, and the broadway tapper censorship. Fun Fact:...

By: Daria Marie

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Art Censorship - Adult Beginner and Intermediate Tap - Spring 2014 - Video

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China crackdown makes it harder to get around the Great Firewall

Posted: at 4:43 am

China is boosting internet censorship to keep people from accessing sites like Google.

HONG KONG (CNNMoney)

The action, confirmed by state media, has affected VPN providers including Astrill, Strong VPN and Golden Frog, which have all reported trouble with connectivity in China, particularly on mobile devices.

China has long blocked access to what it deems as sensitive Internet content -- political commentary, foreign news outlets and sites like Google. Access to Twitter, Facebook and YouTube are also blocked in China.

Taken together, the restrictions constitute the world's largest -- and most effective -- state-sponsored censorship program. The effort, officially called "Golden Shield," is more than a decade old.

Using a VPN allows Chinese and foreigners alike to circumvent the Great Firewall. For around $10 a month, users are able to access blocked websites, Gmail and even Netflix.

Chinese state media described the crackdown as a "healthy development" for the Internet, and one needed to shore up cybersecurity. It follows a move to tighten access to Google's email service that began late last year.

Should the VPN blackout persist -- or expand -- it would be a real headache for companies that rely on the workaround to conduct business.

Related: The Great Firewall of China is nearly complete

Winger Chen, who owns a food and beverage consulting company in China, has always "felt some frustration with [spotty connectivity]," but considers it to be "just part of doing business in China."

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China crackdown makes it harder to get around the Great Firewall

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China adds another brick to Great Firewall

Posted: at 4:43 am

China is boosting internet censorship to keep people from accessing sites like Google.

HONG KONG (CNNMoney)

The action, confirmed by state media, has affected VPN providers including Astrill, Strong VPN and Golden Frog, which have all reported trouble with connectivity in China, particularly on mobile devices.

China has long blocked access to what it deems as sensitive Internet content -- political commentary, foreign news outlets and sites like Google. Access to Twitter, Facebook and YouTube are also blocked in China.

Taken together, the restrictions constitute the world's largest -- and most effective -- state-sponsored censorship program. The effort, officially called "Golden Shield," is more than a decade old.

Using a VPN allows Chinese and foreigners alike to circumvent the Great Firewall. For around $10 a month, users are able to access blocked websites, Gmail and even Netflix.

Chinese state media described the crackdown as a "healthy development" for the Internet, and one needed to shore up cybersecurity. It follows a move to tighten access to Google's email service that began late last year.

Should the VPN blackout persist -- or expand -- it would be a real headache for companies that rely on the workaround to conduct business.

Related: The Great Firewall of China is nearly complete

Winger Chen, who owns a food and beverage consulting company in China, has always "felt some frustration with [spotty connectivity]," but considers it to be "just part of doing business in China."

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China adds another brick to Great Firewall

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Digital bills a 'new level of censorship'

Posted: at 4:43 am

Arthit Suriyawongkul, a researcher at Thai Netizen Network - a civil society group, said the controversial bills appeared to focus more on national cyber security than economic policy.

Arthit pointed out that some key details inside the bills were linked to the National Council for Peace and Order's declarations related to media censorship. If the bills came into effect, the result would be another form of state censorship through cyber and broadcasting services.

He expressed and shared this opinion in an academic seminar called "The digital economy policy and media reform", organised yesterday by Chulalongkorn University's Communications Arts faculty.

Arthit offered the cyber-security bill as an example. Under this draft law, the authorities would be allowed to set up committees able to access and survey the personal data of people across all forms and formats - without court orders.

A similar point between the NCPO's announcement and the new bills was that the Ministry of Information and Communication Technology would be placed under state sovereignty for national security reasons.

Also, panellist Prasong Lertratanawisute, director of the Isra Institute, suggested that to get access and collect personal data, the state authority should be permitted only by the court to ensure and guarantee people's rights were protected, plus freedom of information.

"Any bills involved with this issue must place more concern on privacy and rights of the people," Prasong suggested.

Pirongrong Ramasoota, a lecturer at Chulalongkorn University, said such bills would send the media reform process back to the past. She said another problem was the potential for abuse of power. So, the new bills should be amended to protect people's rights. "Under the bills, it seems the government needs to address public notification if they want to access personal data. This is not enough," she stressed and added that many developed countries in Europe emphasised consent in data collection and fair information practices. This was the point on which the Thai government must be concerned.

Apart from the public surveillance issue, media experts and scholars also expressed anxiety over media development once the laws were in place.

The panellists pointed to the NBTC's fund which is reserved for public research and development, disabled and disadvantaged people, benefits for the elderly and media development for public and community service. It would soon be used to fund government interests once the bills received endorsement by the National Legislative Assembly, they said.

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Digital bills a 'new level of censorship'

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The Alex Jones Show(VIDEO Commercial Free) Tuesday September 30 2014: Ron Paul, Jesse Vent – Video

Posted: at 4:42 am


The Alex Jones Show(VIDEO Commercial Free) Tuesday September 30 2014: Ron Paul, Jesse Vent
Obama Skips Intelligence Briefings -- Date: 09/30/2014 -- --SUBSCRIBE TO PRISONPLANET.TV-- -Today - On this jam-packed Tuesday, September 30 edition of the Alex Jones Show, Alex breaks ...

By: Juliann Melillo

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The Alex Jones Show(VIDEO Commercial Free) Tuesday September 30 2014: Ron Paul, Jesse Vent - Video

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Politicking Ron Paul Blasts ‘Deeply Flawed’ U S Foreign Policy 2015 – Video

Posted: at 4:42 am


Politicking Ron Paul Blasts #39;Deeply Flawed #39; U S Foreign Policy 2015

By: Alan Grubb

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Politicking Ron Paul Blasts 'Deeply Flawed' U S Foreign Policy 2015 - Video

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