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Category Archives: Transhuman News
Plaque Psoriasis Treatment Options – STELARA
Posted: March 27, 2016 at 12:41 am
STELARA is a prescription medicine approved to treat adults 18 years and older with moderate or severe plaque psoriasis that involves large areas or many areas of their body, who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills).
STELARA is a prescription medicine approved to treat adults 18 years and older with active psoriatic arthritis, either alone or with methotrexate.
STELARA is a 45 mg or 90 mg injection given under the skin as directed by your doctor at weeks 0, 4, and every 12 weeks thereafter. It is administered by a healthcare provider or self-injected only after proper training.
STELARA can make you more likely to get infections or make an infection that you have worse. People who have a genetic problem where the body does not make any of the proteins interleukin 12 (IL-12)Proteins that increase the growth and function of white blood cells, which are found in your immune system. and interleukin 23 (IL-23)Proteins that increase the growth and function of white blood cells, which are found in your immune system. are at a higher risk for certain serious infections that can spread throughout the body and cause death. It is not known if people who take STELARA will get any of these infections because of the effects of STELARA on these proteins.
Cancers
STELARA may decrease the activity of your immune systemA system inside the body that protects against germs and infections. and increase your risk for certain types of cancer. Tell your doctor if you have ever had any type of cancer. Some people who had risk factors for skin cancer developed certain types of skin cancers while receiving STELARA. Tell your doctor if you have any new skin growths.
Reversible posterior leukoencephalopathy syndrome (RPLS)
RPLS is a rare condition that affects the brain and can cause death. The cause of RPLS is not known. If RPLS is found early and treated, most people recover. Tell your doctor right away if you have any new or worsening medical problems including: headache, seizures, confusion, and vision problems.
Serious Allergic Reactions
Serious allergic reactions can occur. Get medical help right away if you have any symptoms such as: feeling faint, swelling of your face, eyelids, tongue, or throat, trouble breathing, throat or chest tightness, or skin rash.
Before receiving STELARA, tell your doctor if you:
When prescribed STELARA:
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the Full Prescribing Information, including the Medication Guide for STELARA, and discuss any questions you have with your doctor.
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Transhumanisten | Communicamus, – Ergo Sum..
Posted: March 23, 2016 at 10:40 pm
Was reading this fascinating article about 8 crazy.. Mega-Engineering Projects We Could Use to Rework the Earth.. , and thought.. 1. This is a good opportunity to keep this blog alive.. 2. Should I miss this golden opportunity to provoke / annoy.. my leftist / green / down-wing friends.., hell no..
Dont get me wrong: I am (partly) a socalled down-winger myself, (although predominantly an up-winger), and youd be a fool if you think Im merely out to offend.. I wrote about the up-wing / down-wing political compass here , but lets recapitulate:
DownWingers, according to social epistemologist Steve Fuller :
Some additional points, credit to Fogbanking :
UpWingers, in contrast, according to Fuller:
Additional points by Fogbanking:
With this outline in mind, lets take a look at a couple of those crazy / fascinating, according to taste, Mega-Engineering Projects , but.. be warned, gutmenschen, conspiracy theorists, foot-dragging conservationists, climate-change religionists, cultural pessimists, etc., youre in for an extropian, post-Darwinian ride..
(1) Global Weather Control
According to nanotechnology expert J. Storrs Hall, the author of Nanofuture: Whats Next for Nanotechnology, we could start to build a weather machine later this century Read more..
(2) Terraforming the Worlds Largest Deserts
Approximately one-third of Earths land surface is a desert.. Imagine then, for instance,pumping desalinated seawater from the coast to the Sahara Desert and Australian Outback, creating, instead, lush forests and making vast regions of land fertile and habitable, besides, potentially ending global warming.. Read more..
(7) Eliminating Predation (!!)
Such is the dream of British futurist David Pearce, who so happens to be my favourite transhumanist philosopher, and who imagines a future in which animals are liberated from the never-ending cycle of Darwinian processes and its attendant pain and suffering.. Read more..
If youve never heard of this, in my opinion, great thinker, do check him out, and learn about Paradise Engineering..
Other projects: (3) Creating Artificial Islands ; (4) Creating a New Continent ; (5) Eliminating Vast Swaths of Land ; (6) Assisted Species Migration ; (8) Mass Carbon Capture.. FULL ARTICLE..
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Transhumanisten | Communicamus, - Ergo Sum..
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New York Genome Center Jobs, Employment | Indeed.com
Posted: at 6:41 am
Jobs 1-10 of 44: Be the first to see new jobs
Biocurator, Molecular Diagnostics New York Genome Center - New York, NY 10013 7 days ago
Associate Scientist, Center for Genomics... New York Genome Center - New York, NY 10013 30+ days ago
Post Doc 1 Cold Spring Harbor Laboratory - Cold Spring Harbor, NY 17 hours ago
Post-doctoral Position in Plant Systems... New York University, Center for Genomics & Systems... - New York, NY 5 days ago
Director, Clinical Strategy & Business D... New York Genome Center - New York, NY 10013 20 days ago
Lead Bioinformatics Scientist, Cancer New York Genome Center - New York, NY 10013 30+ days ago
Cancer Biologist New York Genome Center - New York, NY 10013 30+ days ago
Postdoctoral Fellow Mount Sinai Medical Center - Manhattan, NY 30+ days ago
BIOINFORMATICIAN III Mount Sinai Health System - New York, NY 10019 30+ days ago
All Professorial Ranks & Associate Resea... Columbia University - New York, NY 30+ days ago
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Contact – Ron Paul
Posted: at 6:41 am
RonPaul.com is a grassroots-run Fan Site we have no direct contact with Ron Paul!
If youd like to send a message to Ron Paul, please contact the Campaign for Liberty, the successor organization of Ron Pauls presidential campaign, through their online form, or call them at (703) 865-7162.
This information is provided for the convenience of our fellow supporters and other interested parties. It does not imply endorsement by or association with Ron Paul and/or the Campaign for Liberty!
Would you like to contact the grassroots supporters at RonPaul.com? Please only do so for the following reasons
Do not contact us with interview requests, autograph requests, random news not related to Ron Paul, messages intended for Ron Paul personally, anything about Rand Paul, or requests to be removed from a physical mailing list (we dont have one).
Due to the massive volume of emails received each day we can respond only to a very small percentage of requests. If youd like to make a comment or ask a question about Ron Paul, posting a public message at the bottom of this page is a more effective option to make your voice heard. Other supporters will be able to see your message and respond.
Email the authors of this website:
Or complete and submit this contact form:
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Harry Potter’s World Renaissance Science, Magic, and …
Posted: at 6:40 am
The History of Science
Magic comprises the most profound contemplation of the most secret things, their nature, power, quality, substance, and virtues, as well as the knowledge of their whole nature. Heinrich Cornelius Agrippa von Nettesheim, De Occulta Philosophia, 1533
Like Harry, many Renaissance alchemists, naturalists, and physicians struggled with the responsibilities that came with their attempts to understand the world. Heinrich Cornelius Agrippa von Nettesheim, a noted 16th-century occultist, alchemist, lawyer, physician, and, in Harry Potter, a wizard trading card, wrote one of the most famous works on magic, De Occulta Philosophia. Agrippa often criticized the politics, culture, and religion of his time and felt that the ancient magic included in his writings could benefit humanity. The scholar hoped that De Occulta Philosophia would show that ancient magic could be manipulated like a practical science, though he cautioned that any use should be sacred. Agrippa believed that only those with respect for nature could successfully control it and that those who used magic for selfish or immoral reasons would risk their very souls.
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Mindjammer The Roleplaying Game Mindjammer Press
Posted: March 21, 2016 at 8:40 pm
Transhuman Science-Fiction Roleplaying in the Far Future
It is the Second Age of Space. The light of human civilisation, which had flickered and threatened to die, burns bright again with contact with the thousand worlds of space. Humankind laughs, filled with the joys and power of a new-found youth, and strides forth to bring its message of hope and regeneration to the stars The Songs of Old Earth, Book I
The ENnie Award-winning transhuman science-fiction RPG setting returns, in a new edition updated and completely rewritten for the Fate Core rules. Containing all the rules needed to play, including:
Mindjammer The Roleplaying Game can be used to play in the New Commonality of Humankind, or as a complete and detailed transhuman space opera rules set for any science-fiction setting.
Never has there been a greater time of opportunity. Old certainties are dying; the universe is in flux, and for the first time in ten thousand years no one knows what the future will bring. So charge your blaster, thoughtcast your orders to the starship sentience, and fire up the planing engines come and defend the light of humanitys greatest civilisation as it spreads to the stars!
A complete standalone roleplaying game. This book is all you need to play.
Mindjammer The Roleplaying Game is the core rulebook in the Mindjammer line of transhuman science-fiction roleplaying adventure and novels. Join us as we travel through the New Commonality of Humankind, Old Earths greatest civilisation, and rediscover the lost colonies of the distant past.
Transhumanism is a major theme in Mindjammer. Everywhere hyperadvanced technology and synthetic intelligence are transforming humankind, changing individuals into something more than human something other. Play characters caught up in the turmoil of a transformative civilisation: humans, divergent hominids, uplifted animals, synthetic beings. You can even play a sentient starship character!
Characters who survive and thrive grow to be more capable and powerful. More than that, however, your Mindjammer characters can begin to push the very boundaries of what it means to be human. Mindjammer provides detailed rules for how your character can transcend human limitations: acquire multiple bodies, become the sentience embodied in an entire city or even world; step beyond the boundaries of time, language, and individuality. Choose the direction the evolution of the human species will take!
Mindjammer takes place in the far future. Its default setting, the New Commonality of Humankind, is over ten thousand years old, until recently an ancient and stagnant slower-than-light civilisation centred in Manhome, the solar system of Old Earth, and a handful of surrounding star systems. 200 years ago, the Commonality discovered faster-than-light travel, and has been expanding out into the galaxy, discovering lost colonies it settled by slower-than-light generation and stasis ship many thousands of years before.
The Commonality is at once strange and familiar. A vast interstellar shared consciousness called the Mindscape links all Commonality citizens by neural implant, tying the overstretched civilisation together. The Core Worlds around Old Earth are complex and highly advanced, as far from our 21st century and as incomprehensible as we are from the Stone Age. On the ever-expanding Frontier there are civilisations more like our own and just as many far stranger. Everywhere there is turmoil and conflict.
Human Space the theoretical limit of human colonisation by the Diaspora slower-than-light generation and stasis ships extends to a possible 10,000 light years from Old Earth, a sizable proportion of the galactic disk. Commonality Space the limit of current Commonality contact and integration over the past two centuries is much smaller, perhaps 3000 light years in diameter. The schematic below shows the hearts of the 27 Commonality sectors, including the Core Worlds.
Mindjammer is a Fate Core game. Its also standalone, meaning it contains all the rules you need to play. That includes the essentials from the Fate Core SRD, customised and dials set for this action-packed science-fiction setting. It also provides new rules derived from the Fate Core, many of which are released as Open Content under the Open Gaming License.
Mindjammers new rules include rules for creating and playing constructs such as starships, space stations, cities, installations, and vehicles; rules for organisations such as corporacies, governments, and armies and space navies, and for running conflicts between them; and rules for describing and even playing whole cultures. Derived from the Mindjammer 1st edition culture conflict rules but fully consistent with the Fate Core system, the culture rules allow you to run teams of culture agents manipulating entire cultures in the turmoil of Rediscovery.
One of the major features of the Mindjammer game is its emphasis on generating and playing in a science-fiction setting which feels deep and realistic. The rules for planets, star systems, and alien life have been developed with that in mind drawing on the current state of play in cosmology, planetology, and xenoscience, they provide a programmatic way to generate and describe encounters and encounter locations in a way which supports rich science-fiction adventure.
And thats not all. Although these rules are couched in the Fate Core context, theyre also very modular, and can be used in any science-fiction game. Do you want your science-fiction environments to include black holes, molecular clouds, protoplanetary disks, exotic biospheres, and rich and consistent ecosystems? Look no further.
Mindjammer The Roleplaying Game is the first in an extensive line of Mindjammer RPG products. Although the core book contains all the rules you need to play, we have a product pipeline of adventures, campaign packs, atlases, and sourcebooks detailing the New Commonality of Humankind and the Mindjammer universe. Coming soon:
Future products include the Commonality Atlas 1: The Darradine Restoration, The Black Zone, Twilight, Commonality Atlas 2: The Successor States, Solenine, The Comsentience Sourcebook, and much more!
This website itself is a content resource for your Mindjammer games.
Mindjammer is also the name of the first novel in the Mindjammer series, available now from Mindjammer Press! By ENnie award-winning RPG author Sarah Newton, its an action-packed tale of mind-bending technologies in the unimaginably far future, as the human race struggles to fulfil its transhuman destiny.
In the seventeenth millennium, the New Commonality of Humankind is expanding, using newly-discovered faster-than-light travel to rediscover lost worlds colonised in the distant past. Its a time of turmoil, of clashing cultures, as civilizations shudder and collapse before the might of a benevolent empire ten millennia old.
In the Solenine Cluster, things are going from bad to worse, as hyper-advanced technologies destabilise a society in chaos. Thaddeus Clay and his special ops team from the Security and Cultural Integrity Instrumentality are on the trail of the Transmigration Heresy. But what they find is something beyond even their imagining and something which could tear the whole Commonality apart!
Available now from DriveThru, Amazon.com (trade paperback / ebook) and Amazon.co.uk (trade paperback / ebook), and hobby and game stores everywhere!
Complex, gripping, and the most original sci-fi youre likely to get G*M*S Magazine A very exciting and intelligently-written novel that should be on the reading list of every SF fan! Stargazers World William Gibson-like in the intensity of the ideas it introduce a heady mixture of action, crunchy science fiction elements and that perennial cyberpunk or transhuman question: what does human mean? Science-fiction may have a new star forming in its firmament. Shores of Night Thrilling adventure and mystery wrapped up with an inventive, mind-bending look at mankinds future. Howard Andrew Jones, author of The Desert of Souls
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Eczema – Medical Disability Guidelines
Posted: March 20, 2016 at 7:41 am
History: The most common complaint of eczema is itchiness (pruritus), redness, and tiny bumps or blisters. If untreated, the skin can become thick, scaly, and dry, with areas of hair loss and color changes. The individual may relate a history of work or recreational activities in which the skin is exposed to water, moisture, sun, or new personal care products.
Physical exam: In general, eczema presents with redness, warmth, swelling (edema), tenderness, weeping, crusting, scratches and cracks (excoriations), and thickened and scaling skin with a diffuse border.
Skin changes associated with atopic dermatitis are variable and include excoriations; wet, raised bumps (papules); thickened, red, gray, or scaly skin (lichenification); red, fluid-filled bumps (vesicles); and crusted lesions.
Contact dermatitis presents as areas of reddened (erythematous) and swollen (edematous) skin that later develop small and large blisters (vesicles and bullae, respectively). The pattern, shape, and location of the contact dermatitis rash help identify the causative substance. Hand eczema may present with dryness and cracking of the skin, with some redness and swelling. A variation of this condition, dyshidrotic eczema, has small, very itchy bumps along the fleshy parts of the palms and sides of the fingers. Nummular eczema has round scaly patches that look similar to ringworm and are found on the trunk, the back of the arms and hands, and the shins. Stasis dermatitis often exhibits dark red discoloration and swelling of the skin on the lower leg, ankle, and top of the foot. Stasis dermatitis lesions can become irritated and inflamed and in many cases can result in skin ulcers.
Asteatotic eczema (winter itch) presents with fine cracks over the front surface of the thighs and shins and possibly a dry, shiny appearance. Scabies presents with the classic eczematous lesions found primarily on the ankles, webs of fingers and toes, scalp, wrists, bellybutton (umbilicus), genitals, or the nipples. Seborrheic dermatitis presents as red, itchy, scaly areas, primarily on the face, scalp, groin, anogenital region, and/or below the breasts. Lichen simplex chronicus is a late stage of eczema and consists of thickened, scaly skin due to chronic rubbing or scratching. Common areas for lichen simplex chronicus are the back of the neck, tops of the feet, and ankles.
Tests: Though most eczemas are diagnosed through the history and physical exam, a scraping of the lesion should be examined under the microscope to rule out certain other skin disorders. Skin biopsy is done when persistent eczema does not respond to treatment. Skin patch tests, provocative challenges, and some immunological testing may be required. Elevated total IgE denotes an underlying allergy.
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Eczema / Exzema – Information and treatment
Posted: at 7:41 am
What is Eczema? Eczema (pronounced as 'EK-zeh-ma') comes from two Greek words, 'ek' meaning out and 'zema' meaning boils. Basically eczema, which is also called dermatitis, is a medical condition wherein the skin swells. The discomfort and pain arising from the small blisters of the skin makes it feel as if it is boiling. Both children and adults may contract eczema, but it usually occurs in infants. The cause of eczema is not yet known, but it often affects those having a family history of allergies. A lot of people suffering from eczema have asthma or allergic rhinitis, or have relatives who do. According to the National Institute of Health, approximately 15 million people have eczema in the United States alone. Around 10 to 20 percent of babies have eczema, but the condition will greatly improve by the time they are 5 and 15 years old in nearly have of them. Others will continue to have the said condition for the rest of their lives. Common Types of Eczema There are many types of eczema, each having different symptoms and causes. The most common are the following:
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Eczema / Exzema - Information and treatment
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Eczema – Skin Problems
Posted: at 7:41 am
Eczema is a common skin problem in individuals with brown skin including those of Asian, Latino and African descent. It is felt to be the second most common skin disease in African-Americans. Although it is unknown if the incidence of eczema is increased in Latinos, one study found a significantly higher percent of Mexican American adolescents with eczema than white and African American adolescents. A study of Chinese, Vietnamese and white infants found a higher incidence in the Chinese and Vietnamese infants. Eczema can be a difficult and embarrassing challenge for anyone, but for a person of color with eczema, there are multiple concerns including disfiguring discoloration of the skin (hyperpigmentation or hypopigmentation). Also, in brown skin, eczema may appear differently than in white skin thus making the correct diagnosis more difficult.
In cases in which eczema is inherited along with the conditions, asthma and hay fever, it is termed, atopic dermatitis. Eczema usually appears in childhood or adolescence and frequently continues throughout adulthood. The course of eczema varies with intermittent flares which are precipitated by the following factors:
Eczema is a diverse disease that can range from mild skin irritation to severe rashes. In skin of color, eczema may not have the typical appearance of red, flaky patches. Instead, it may appear as dry ashen, brown or gray patches. In addition, in black skin, eczema may appear as rough, brown papules (bumps) near follicles which is termed, follicular papules.
There are three stages of eczema: acute, subacute and chronic. An individual with eczema may have only one stage or the stages may progress from one to another.
Acute Eczema
A major symptom of eczema is very intense itching. Scratching is a natural response to the itching. However, melanin in brown skin makes it more reactive to itching, irritation and inflammation. When scratched or rubbed, the inflamed skin can become hyperpigmented, thickened and crusted. It is important to break the itch-scratch cycle to prevent further hyperpigmentation.
Treatment Once eczema flares in brown skin, treating it promptly is key to not only eliminating the itch, but also avoiding hyperpigmentation or hypopigmentation. While there is no cure for eczema, the condition can be kept under control by modifying certain daily routines and receiving prompt treatment.
Prevention of eczema is as important as prescription medication. Understanding the causes of eczema, trigger factors and proper skin care techniques are the first step to treating eczema. Some individuals with eczema will need to avoid certain foods, allergens or medicines.
Avoiding skin irritants, including chemicals and clothing, is an important preventative measure for individuals with eczema.
All individuals with eczema will need to modify bathing habits, skin care products and other chemicals that come into contact with the skin. The following patient education tips are commonly recommended by dermatologists.
Corticosteroids topical, oral and injected are the mainstay of treatment of eczema. The selection of the formulation depends upon the severity of the eczema. For mild to moderate eczema, topical corticosteroids, formulated as creams, ointments, lotions, foams or oils are commonly prescribed. These agents, which come in many different strengths from class 1 (superpotent) to class 7 (low potency), are usually prescribed twice daily for a two to three week period. Low potentcy corticosteroids are commonly used to treat the face, body folds (groin, axillary) and in the diaper area. More potent steroids are applied on other parts of the body. For lichenified plaques and regions such as the palms and soles superpotent steroids are often prescribed. Although topical steroids treat the inflammation that is characteristic of eczema, serious complications can develop from overuse or prolonged use, especially those that are superpotent.
Complications of topical steroidsThinning of the skin
For severe eczema, oral steroids (Prednisone) or injected steroids (Kenalog, Aristocort) may be necessary. They are prescribed for a limited period of time only and are reserved for the most severe cases.
TIMS or Topical Immunomodulators are topical agents (calcineurin inhibitors) that are used for the treatment of eczema. They do not contain steroids and therefore do not carry the risks associated with that medications. There are two types of immunomodulator creams: Tacrolimus (0.03% and 0.1% Protopic) and pimecrolimus (1% Elidel). Immunomodulators are applied twice daily until the eczema clears. Itching, burning and irritation are possible side effects. There has been concern raised regarding cancers in laboratory animals fed immunomodulators orally. Further long-term human studies are needed to completely understand the side effects with topical immunomodulator therapy.
Non-TIMS are non-steroid, non-tims topical creams that have been recently developed for the treatment of eczema. One of the most recently approved is Mimyx. It is not only a good emollient, but treats eczema and can be used for chronic cases or eczema.
Phototherapy or light treatment is an effective treatment for eczema. With phototherapy, various wavelengths of sunlight (UVB, UVA, combined UVA/UVB, UVA1, or narrow-band) are administered in a unit that is similar to a telephone booth but which is lined by fluorescent appearing light bulbs. The type of phototherapy that you will receive will be determined by your dermatologist. It is usually administered twice weekly. Possible side effects of phototherapy are redness, sunburn, or dryness. Long-term side effects, which are more likely with white skin, are possible skin cancers and enhanced aging.
Antihistamine pills relieve itching associated with eczema. There are three classes of antihistamines (H1, H2, H3). Type H1 antihistamines (e.g. hydroxyzine, diphenhydramine) are helpful in breaking the itch-scratch cycle. Since they may cause drowsiness, they should be given at bedtime. Type H2 and H3 antihistamines are generally non-sedating and are also helpful in treating eczema. Your doctor will select the antihistamine that is most appropriate for your eczema.
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Dermatitis (eczema). DermNet NZ
Posted: at 7:41 am
Facts about the skin from DermNet New Zealand Trust. Topic index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Dermatitis affects about one in every five people at some time in their lives. It results from a variety of different causes and has various patterns.
The terms dermatitis and eczema are often used interchangeably. In some cases the term eczematous dermatitis is used. Dermatitis can be acute or chronic or both.
An in-between state is known as subacute eczema.
Psychological stresses can provoke or aggravate dermatitis, presumably by suppressing normal immune mechanisms.
An important aspect of treatment is to identify and tackle any contributing factors (see above).
Dermatitis is often a long-term problem. When you notice your skin getting dry, moisturise your skin again and carefully avoid the use of soap. If the itchy rash returns, use both the moisturiser and the steroid cream or ointment. If it fails to improve within two weeks, see your doctor for further advice.
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