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Category Archives: Transhuman News

TIGERISS roars toward space station spot – The Source – Washington University in St. Louis – Washington University in St. Louis

Posted: August 30, 2022 at 11:04 pm

Physicists from Washington University in St. Louis are developing a new experiment envisioned for the International Space Station as part of NASAs Astrophysics Pioneers Program. The Trans-Iron Galactic Element Recorder for the International Space Station (TIGERISS) will be designed to measure the abundances of ultra-heavy galactic cosmic rays. Pioneers Program missions have a total cost cap of $20 million.

TIGERISS is an evolution of the TIGER and SuperTIGER balloon-borne instruments also created by scientists in Washington Universitys Department of Physics in Arts & Sciences over the past three decades.

TIGERISS has the unprecedented ability to measure galactic cosmic ray abundances with single-element resolution spanning the periodic table from boron to lead, said Brian Rauch, research associate professor of physics in Arts & Sciences, principal investigator for the TIGERISS program. At the end of the five-year mission, our transformational measurements will increase understanding on how the galaxy produces and distributes the elements.

TIGERISS also aims to strengthen and add to the new generation of leaders emerging in galactic cosmic ray instrumentation and analysis for future space-flight missions, said Rauch, who is a faculty fellow of the universitys McDonnell Center for the Space Sciences.

Other Washington University team members include Wolfgang Zober, a physics PhD candidate, as science principal investigator for TIGERISS, with engineering support from Richard Bose and Izabella Pastrana, all in physics.

All stars exist in a delicate balance they need to put out enough energy to counteract their own gravity. That energy comes from fusing elements together to make heavier ones, including carbon, nitrogen and oxygen, which are important for life as we know it. But once a giant star tries to fuse iron atoms, the reaction doesnt generate enough power to fight gravity, and the stars core collapses.

This triggers an explosion known as a supernova, and shock waves cast out all of those heavy elements that had been made in the stars core. The explosion itself also creates heavy elements and accelerates them to nearly the speed of light particles that scientists dub cosmic rays.

But thats not the only way heavy atoms can form. When a super-dense remnant of a supernova called a neutron star collides with another neutron star, their cataclysmic merger also creates heavy elements.

TIGERISS wont be able to point out particular supernovae or neutron star collisions, but would add context as to how these fast-moving elements are accelerated and travel through the galaxy, Rauch said.

So how much do supernovae and neutron star mergers each contribute to making heavy elements? That is the most interesting question we can hope to address, Rauch said.

TIGERISS measurements are key to understanding how our galaxy creates and distributes matter, said John Krizmanic, TIGERISSs deputy principal investigator, based at NASAs Goddard Space Flight Center in Greenbelt, Md.

Contributing institutions on TIGERISS include NASAs Goddard Space Flight Center; Howard University; Pennsylvania State University; University of Maryland, Baltimore County; and Northern Kentucky University.

Commercial engineering company KBR Inc. also joined in the proposal, which was supported by Washington Universitys Research Development Office and the McDonnell Center for the Space Sciences. Aerospace company Boeing Co. contributed a letter of support.

Snagging a spot on the International Space Station has many advantages over flying an instrument on a long-duration scientific balloon, as Rauch has done in the past.

But those grueling balloon flights from Antarctica provided compelling science results that clearly demonstrated the utility of the basic experimental approach.

Rauch credits previous research by physicists Martin H. Israel and W. Robert Binns including both balloon-borne instruments and studies with space instruments for helping to establish Washington University as a leader in the study of cosmic rays.

On the International Space Station, the TIGER instrument family would soar to new heights. Without the interference from Earths atmosphere, the TIGERISS experiment could make higher-resolution measurements and pick up heavy particles that wouldnt be possible from a scientific balloon.

A perch on the space station would also allow for a larger physical experiment 3.2 feet (1 meter) on a side than could fit on a small satellite, increasing the potential size of the detector. And the experiment could last more than a year, compared to less than two months on a balloon flight. Researchers plan to be able to measure individual elements as heavy as lead, atomic number 82.

Compared with its predecessors, TIGERISS will have a greatly improved capability to definitively identify ultra-heavy galactic cosmic ray nuclei, Rauch said. This has been demonstrated in component accelerator tests at CERN, including using silicon strip detectors in place of scintillators.

TIGERISS joins four experiments in the Pioneers Program that are at a more advanced stage of development, having passed their initial review this year. Rauch is the institutional principal investigator for Washington University on one of these other Pioneers Program experiments, the PUEO program led by the University of Chicago.

Read more about TIGERISS on the NASA webpage.

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Vein Scans, Blood Tests on Station Prolong Astronaut Health – NASA Blogs

Posted: at 11:04 pm

The seven-member Expedition 67 crew poses for a portrait inside the International Space Stations Harmony module.

Vein scans and human research samples comprised the majority of the research schedule for the Expedition 67 crew members on Tuesday. Spacesuit work is also ongoing aboard the International Space Station as the cosmonauts prepare for a spacewalk.

Three astronauts took turns on Tuesday morning using the Ultrasound 2 device to scan each others neck, shoulder, and leg veins. NASA Flight Engineers Kjell Lindgren, Bob Hines, and Jessica Watkins started the day inside the Columbus laboratory module with researchers on the ground remotely guiding the biomedical study. The ultrasound scans produce an echo that bounces off human tissue converting it to a video signal that is downlinked to Earth in real-time for analysis. Scientists view the imagery to observe how microgravity affects crew health.

The crew members also regularly collect their own blood, saliva, and urine samples, stowing the specimens in science freezers for later analysis. Shortly after Lindgren woke up on Tuesday, he spun his blood samples in a centrifuge for the Phospho-aging study to understand space-caused accelerated bone loss and muscle atrophy. ESA (European Space Agency) Flight Engineer Samantha Cristoforetti collected her blood and urine samples during the afternoon for future examination. Earlier, she documented her meals for a nutrition study then swapped material samples inside the Electrostatic Levitation Furnace, a high-temperature research facility.

Cristoforetti and Watkins also spent time inside the U.S. Quest airlock servicing a U.S. spacesuit. The duo split their day on a variety of suit activities including swapping components and cleaning cooling loops. Hines spent his afternoon charging computer tablets and downloading security updates for the devices.

Commander Oleg Artemyev and Flight Engineer Denis Matveev spent the day activating and inspecting a pair of Orlan spacesuits, testing their communication systems, and performing leak checks. The two cosmonauts have been busy this week preparing for an upcoming spacewalk to prepare the European robotic arm for payload operations on the stations Russian segment. Flight Engineer Sergey Korsakov worked throughout Tuesday maintaining electronics systems and life support hardware inside the orbiting labs Russian modules.

Learn more about station activities by following thespace station blog,@space_stationand@ISS_Researchon Twitter, as well as theISS FacebookandISS Instagramaccounts.

Get weekly video highlights at:http://jscfeatures.jsc.nasa.gov/videoupdate/

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The International Space Station will deorbit in glory. How’s your legacy tech doing? – The Register

Posted: at 11:04 pm

Opinion The International Space Station is showing its age. It's older than a third of the population, over two and a half billion people who have never known a time without humans in orbit.

Bits and pieces of it keep going wrong, most recently the EVA spacesuits; Russia may or may not be about to bail; and it's more Red Dwarf than the Enterprise when it comes to space germs.

You thought it was difficult getting a cleaner to come to your apartment in the city? From one point of view, it's worn out, super-expensive to run, and is not contributing much to space exploration any more, and is soaking up far too much of space engineers' brain time.

Does that apply to any legacy technology you're familiar with? IT legacies don't make cool videos of the Earth from space or astronauts tumbling in microgravity, so they lose out heavily to the ISS on the public relations front. They won't be consuming 15 percent of a $22 billion budget [PDF] either.

The most important difference between the ISS and your line-of-business app still working gamely away in a virtualized Windows XP (which still has over 0.3 percent market share for heaven's sake) is that the ISS is a project designed to die. NASA is planning its demise in the next five to eight years [PDF].

Along with the headline stuff like scientific research and technology testing there are many thousands of results that are ours to enjoy the world also honors the work of the ISS because it benefits from the experience of long-term crewed missions. On the roadmap of space, the ISS bridges the misguided missile of the Shuttle and the return to the Moon and beyond.

When we next leave orbit outwards instead of inwards (the ISS will come crashing down into the Pacific Ocean, apparently), it'll be because of the legacy of the ISS.

Legacy IT could play a similarly honorable role in organizational long-term planning. It doesn't. Nobody thinks in those terms. If you're very, very lucky, the solitary nod to posterity may be some documentation that's been kept a bit up-to-date (you won't be very, very lucky).

Project lifecycles become more myth than management after the work's been done. If anyone asks at the start of a project: "What do we expect to learn by building and running this, and how do we migrate that knowledge onwards?" it's not part of tradition or general practice.

But the fact that such ideas seem more alien than 'Oumuamua is in part due to the chronic amnesia that afflicts corporates so desperate to reinvent that they forget biological evolution is nothing but refactored legacy.

It's also your fault, IT practitioners, and your determination to keep the science in computer science science-fiction. Take the agile methodology of software development.

The idea first took rigorous shape with rules and reasoning in 2000, the same year that the first crew boarded the ISS.

It recognized the problems of the strictly sequential project plan, it had good results that made agile a jargon term outside software, and it fed into DevOps and the cloud. You can easily find many discussions of how well it did these things, whether its time has passed, and what strengths and weaknesses have been exposed over two decades. What you cannot find is an attempt to systematically analyze what agile has taught us about software engineering and project management, in its own terms or in the context of the total history of software.

Our skills in science and technology don't progress linearly, with each step an incremental good. Many fashionable ideas look good but are rarely mentioned in polite society after they fail to match the hype. But do we learn from these failures through a shared narrative?

Software, too, has its fashion failures: Java everywhere, anyone? And the unfashionable can also rise (JavaScript, yo). But what does this mean for the future?

It's not that there's any lack of discussion about every aspect of the fabric of our digital world; it's that there's no sense of coherent intellectual analysis. It's like Anglophone politics, where any tradition of intellectual analysis has been abandoned in favor of the hot take.

Even something as fascinating and profound as the co-dependent rise of open source and the internet has received less academic attention than the prehistory of ant parasitology. Yet there's no part of commerce or culture untouched by the former.

That the ISS could be built and run with a probable life of 30 years is because the science, technology, and engineering live up to their identity as disciplines. That's how a legacy of enrichment and progress happens.

That the term legacy in IT is a mark of shame and technical debt is because we've shirked the brainwork of making it a proper discipline. As we move deeper into the 21st century with all the problems that bad digital can bring, it's our responsibility to make it one of the great human endeavors. Serious intent is no crime. Fiery death from above is not an option.

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Educational space center to launch by 2023 in Reston – FFXnow

Posted: at 11:04 pm

The space center is expected to open by 2023 (courtesy Interstellar Dreams)

In the near-future, Reston will have an educational space center to call its own.

Interstellar Dreams, a project through The Pearl Project Institute for Innovation in STEM literacy, is actively scouting for a 40,000-square-foot space center in Reston. The center, which is expected to open by next year, will include training and simulations in real-world and virtual learning environments.

The Reston center will be preceded by a smaller prototype set to open Sept. 10 at George Mason Universitys College of Science Research Hall in Fairfax, according to a press release.

We are looking for stars to get us to the stars, said Robin McDougal, founder and CEO of Interstellar Dreams, a nonprofit focused on nurturing future STEM professionals. Building a Space Center is a needed tool to help inspire, educate, and train emerging and current workersthat are reflective of our whole population to ensure we are ready to explore the universe. We plan to start here in Northern Virginia where this industry is booming.

The company is raising $5 million to build a mission command, space station and planetary habitat. These features will have floor to ceiling LED screens and equipments. Visitors can come for an hour or a day to be in the environment, and mission commanders will lead groups in exercised and simulations.

The project will primarily be funded by donations, sponsorships and memberships.

McDougal is a former Fairfax County Public Schools advanced academic educator and describes herself as a STEM literary advocate.

The announcement was made yesterday (Monday) in the backdrop of NASAs moon launch of Artemis I. The launch was delayed that day.

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What is ISRU, and How Will it Help Human Space Exploration? – Universe Today

Posted: at 11:04 pm

As Artemis 1 prepares for its maiden launch with the goal of putting astronauts back on the Moons surface within the next few years, the next question is how will astronauts live and survive its surface? Will we constantly ferry all the necessary supplies such as water and food from Earth, or could astronauts learn to survive on their own? These are questions that a discipline known as ISRU hopes to answer both now and in the years to come. But what is ISRU, and how will it help advance human space exploration as we begin to slowly venture farther away from the only home weve ever known?

ISRU stands for in situ resource utilization where in situ basically means in place or from the original place, said Bailey Burns, a System Engineer with Paragon Space Development Corporation, who also received a Master of Science in Space Resources from the Colorado School of Mines. This basically is talking about using the resources that are there. This is a really big topic as we talk about space exploration because we cant bring everything with us from Earth when we go to space. One of the largest reasons for this is the gravity well of Earth. To escape Earths gravity takes a lot of rocket power. They are estimating that it takes about $10,000 to put 1 kg into space. The short answer is ISRU is about living off of whats in space to provide a permanent and sustainable human presence in space.

Dr. Norman Wagner, who is the Unidel Robert L. Pigford Chair in Chemical Engineering at the University of Delaware, believes that both landing pads and habitats are the two most important aspects the Artemis crewed missions should focus on when they first get to the Moon. He says this is due to rocket exhaust being able to create projectiles, while radiation and thermal shielding also being necessary or we will be living underground.

As stated, the Artemis astronauts will require both food and water to survive on the Moon, but how will they get both without constant resupply from Earth? A recent study explored how Moon dust can be turned into cement to build structures such as landing pads, but what about water and food? One possible avenue is growing it in the lunar regolith itself, which a recent study attempted with lunar regolith returned from the Apollo missions with marginal success. For water, the south pole of the Moon has been designated as a possible landing site for Artemis 3 astronauts due to its water ice content deep within some of its craters, specifically Shackleton Crater.

While the Moon lacks an atmosphere, it is currently hypothesized that pockets of water ice might exist within the depths of these craters due to the lack of sunlight reaching it. This is because the Moons axial tilt is only about 5 degrees relative to its orbit, meaning there are places at both poles that either receive constant sunlight, or none at all. Water is by far the most important need for humans, and water ice found on the Moon can not only be used for drinking and bathing, but can also be electrolyzed to make oxygen, as they currently do in the International Space Station.

In terms of Artemis, I do believe what were doing right now is the best approach, said Burns. We really need to figure out how to utilize water best. After all, we are talking about having a human space presence and humans can only go three days without water. This makes this one of the largest concerns for humans in space. I think the next big areas will be figuring out how to use lunar regolith as a building material such as concrete here on Earth and utilizing helium 3 as a clean energy source.

While Artemis astronauts will only be a few days from Earth in case something goes wrong, future astronauts going to Mars wont be so lucky. Its a six-month journey each way depending on the alignment of Earth and Mars, so ISRU will play an even bigger role there than on the Moon.

ISRU is going to be really beneficial to the Moon and Mars, said Burns. Weve already talked about a few of the resources we can find there. Another one for Mars specifically is the abundance of carbon dioxide in the atmosphere. Now. It would be better if it had oxygen for us like Earth but having tons of CO2 is the next best thing. That means we dont have to transport oxygen from Earth to Mars, which is really expensive, we just need to work on technology such as MOXIE which turns CO2 back into oxygen for us to breathe. Of course, with a carbon byproduct as well. The reason all of this is super beneficial, as I mentioned, its because it means we dont have to bring these things from Earth, and we can have truly sustainable space civilizations on the Moon and Mars.

As always, keep doing science & keep looking up!

Lead Image: Artist concept of Artemis astronauts on the Moon. (Credit: NASA)

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Rapamycin Drug Used in Cancer Therapy Found to Increase Human Lifespan [Study] – Nature World News

Posted: at 10:57 pm

Aging has been one of the mysteries amongst members of the scientific community for many years; although some living organisms are biologically immortal, a number of animals like humans are not.

Defined as the as the process of cellular or molecular damaging over time, biological aging is an imminent evolutionary process. It has been a subject of research pertaining to human health and its related diseases.

While human lifespan extension is possible, the notion of reaching beyond the projected age limit of a person is still theoretically unclear.

Such boundary is the case since evidence showed that a particular variable could still be hard to attribute if a prolonged lifespan is potentially achieved.

However, scientists are focusing on slowing aging, which can address its associated health conditions and diseases.

In a new study, scientists from Germany are claiming that a brief exposure to rapamycin, a drug typically used in cancer therapy, can increase human lifespan at an unspecified rate.

It can also have the same anti-aging effects of a lifelong treatment.

This can be achieved under a brief exposure to the anti-aging drug or there will be side effects, as previously found in some cancer patients.

In the past, cancer patients have reportedly experienced health complications from rapamycin when they take it as a lifelong anti-aging treatment.

However, the new research found that even a brief or short-term usage of the drug can have a dramatic impact on longevity, while decreasing the side effects.

(Photo : Photo by STRINGER/AFP via Getty Images)

In the new paper published in the journal Nature Agingon Monday, August 29, researchers from the Max Planck Institute for Biology of Ageing explored the long-lasting geroprotection from brief rapamycin treatment during early adulthood.

According to a news release on Monday, the Max Planck Institute for Biology of Ageingsaid this is made possible due to persistent increase intestinal autophagy.

This means that young adults who will be briefly exposed to the cancer drug can be spared or protected from the age-related health hazards in the intestine, which eventually extended their lives.

The assertion of an anti-aging remedy had its roots from previous experiments on laboratory animals.

Also Read:Aging Mystery: Crocodiles, Salamanders and Turtles Could Hold the Key Behind Aging and Longevity, Scientists Say

The World Health Organization (WHO)explains that aging leads to gradual decrease in mental and physical capacity since cells are damaged at a biological level.

In addition, they also yield in the increased risk of disease and ultimately death.

However, the WHO claims that such changes are neither linear nor consistent since they are dependent in a person's age in years.

Compared to ancient times, the international health body states that people are living longer worldwide.

This is due to associated technological advancements, primarily in the field of medicine, which has developed vaccines and various treatments for ailments and diseases.

Between 2015 and 2050, the ratio of the world's population aged more than 60 years will increase from 12% to 22%, according to the WHO.

Related Article:Scientists Reverse Aging and Extend Lifespan of Mice in a New Study

2022 NatureWorldNews.com All rights reserved. Do not reproduce without permission.

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Eating Healthy: Why Eating Grapes Would Increase Lifespan | The Guardian Nigeria News – Nigeria and World News Guardian Life The Guardian Nigeria…

Posted: at 10:57 pm

By Chinelo Eze

30 August 2022 | 2:05 pm

Doctor John Pezzuto and his Western New England University team have published research that demonstrates the amazing effects of grape consumption as well as its longevity effects on lifespans. The journal Foods published one paper and it showed that adding grapes to a high-fat diet, which is generally eaten, in an equivalent amount to slightly

Doctor John Pezzuto and his Western New England University team have published research that demonstrates the amazing effects of grape consumption as well as its longevity effects on lifespans.

The journal Foods published one paper and it showed that adding grapes to a high-fat diet, which is generally eaten, in an equivalent amount to slightly under two cups per day, resulted in a decrease in fatty liver and an increase in lifespan.

According to Pezzuto and his team, these investigations give the proverb affirmation to what is said about being what you eat, elevating the phrase with a new meaning. He claimed that the research with grapes demonstrated real alterations in genetic expression. He has produced approximately 600 scholarly articles.

Grapes boosted overall antioxidant genes and postponed natural death in conjunction with a high-fat diet. Pezzuto recognised that extrapolating a mouses lifespan to a human beings is not an exact science. The shift seen in the study, according to his best guess, would add an additional 4-5 years to a persons lifespan, he said.

In the journal Antioxidants, Dr. Pezzuto and his group of researchers published yet another study. It stated that eating grapes improved behaviour and cognition, which were negatively impacted by a high-fat diet and altered gene expression in the brain.

In a third study, a group under the direction of Dr. Jeffrey Idle showed that grapes alter not only the expression of genes but also the metabolism.

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Beauty Bets on Longevity WWD – WWD

Posted: at 10:57 pm

PARIS The beauty industrys lexicon and focus keep expanding. Health, then well-being, were buzzwords in the recent past. Now, with their convergence and scientific advances, longevity is becoming a key talking point and industry shape-shifter.

Its influence is expected to be widespread, on everything from product creation to services, as peoples lifespan and mind-set keep stretching.

Our life expectancy has been considerably extended, thanks to recent advances in the medical field, said Virginie Couturaud, scientific communications director at Parfums Christian Dior. Today, enabling the human body to remain in good health as long as possible is a major research challenge.

In this quest for good health, aging, defined by the scientific community as a continuous process of alteration of the different functions of the body, seems to be a hindrance, she continued. Recent discoveries have shown that this process is not inevitable, and that it is possible to slow it down and even partially reverse it. This awareness has led to the development of a new research area, whose objective is to explore the different ways to reverse the aging process, offering new perspectives for human health.

In the long term, this work will make it possible to significantly extend the human health span rather than the life span, so that people can get older in a healthier way, Couturaud said.

Industry experts describe the growing emphasis on longevity as more of an evolution than a revolution.

The wellness trend is not new, said Charles Rosier, chief executive officer of Augustinus Bader. But that wellness trend is evolving with the fact that we have more information and research being made on the topic of longevity and how to measure longevity.

A few years ago, the main pillar was the length of the telomere, he continued, referring to the natural end of a eukaryotic chromosome. Now, other criteria have come into play and other discoveries on the topic.

A confluence of phenomena contributes to this growing focus on managing aging.

Youve got the consumerism of health care being powered by artificial intelligence, technology and stem cell research so people taking more proactive approaches to their health care, and seeing that in holistic inside and outside ways, said Lucie Greene, founder and CEO of trend forecasting consultancy Light Years.

Also, as the oldest Millennials turn 40 or 41, age-related concepts and services are starting to skew toward them design- and discourse-wise.

Greene spotlighted concepts such as Millennial med-spa Ever/Body, for instance, which was launched by former Clinique executive Kate Twist as an alternative to traditional cosmetic dermatology offices. The chain, which raised $38 million in Series B funding last year, offers laser facials, Botox, HydraFacial, fillers and laser hair removal.

The VSpot medi spa, another example, is for vaginal rejuvenation and has on its menu treatments such as non-surgical breast lift, intimate lightning and hormone replacement therapy.

Modern Age, a wellness clinic officially opened a New York City location in April. Its tag line: Feel good. Age well.

The clinic takes a holistic approach to take control of your aging journey, combining things like IV drips for skin and hair health, energy and stress; micro-needling and hormone therapies.

Modern Age delves into clients subjective age how old one feels and claims lowering that can lead to a longer, healthier life.

Female biohackers Lauren Berlingeri and Katie Kaps teamed to open Instagram-friendly infrared outposts, called HigherDose, also in New York. It has a location at the 11 Howard hotel and another in the Williamsburg section of Brooklyn, N.Y. The brand became famous for users sweaty, sexy sauna selfies.

Eventually, the duo decided to build out a product line for infrared enthusiasts to take home. There is the Infrared Sauna Blanket for $599, the Infrared PEMF Mat for $1,095 and the Red Light Face Mask for $299. The technologies are meant to be stacked and build on one another for additional wellness benefits.

The sauna blanket provides an at-home sauna experience, while the PEMF mat is said to have electromagnetic frequency that is similar to the earths core, for calming, grounding [and] relaxing, Berlingeri said during WWDs Beauty CEO Summit in May.

The red light technology featured in the face mask is well-known for skin benefits, but the founders also purport that red light feeds the mitochondria of every single cell to produce something called ATP, which is energy, which means that every single one of your cells in your body is functioning better.

The tech is said to be a mood booster, too.

During a separate interview, Berlingeri called the face mask her and Kaps Trojan Horse into the beauty space.

What were focused on is longevity and vitality, Berlingeri said. It just so happens that red light is an amazing antiaging beauty tool, as well. But here we are trying to educate people [that] its beyond decreasing wrinkles.

Its been exciting to be in this beauty space as two female biohackers, she continued. [In addition to] wanting to feel our best, looking our best is something that is top of mind for us, too. But weve always felt [that] when you focus on wellness, then beauty comes effortlessly. Its from the inside out.

We do feel like theres so much untapped upside around this whole idea of longevity, vitality and optimization, [with] men still dominating that space more than women are, Berlingeri said. Which is kind of an interesting concept, because we feel like women are the original biohackers.

She and Kapps believe theres no brand in the wellness space owning longevity.

We really plan to do that, Berlingeri said. Biohacking is the ultimate way to achieve vitality, longevity and just looking and feeling your best.

The pair seeks to revolutionize topicals and ingestibles that can help people achieve beauty. HigherDose recently launched High-Dration Powder, based on the whole fruit of watermelon and coconut, mixed with electrolyte and Himalayan salt.

Clinique La Prairie, of Montreux, Switzerland, offers among its treatments a protocol using peoples own stem cells that are clinically harvested and reinjected in order to revitalize skin using the bodys natural resources for regeneration, according to Simone Gibertoni, the clinics CEO and cofounder of Holistic Health.

The race is on for beauty companies to tap into longevity.

Dior Science and its parent company LVMH Mot Hennessy Louis Vuitton have for decades worked with external scientific specialists, and the brand has been pioneering in skin antiaging discoveries.

In early July, Dior said it had entered into a research collaboration with Vadim N. Gladyshev, a professor of medicine at Brigham and Womens Hospital, in Boston, with the aim of reversing cellular aging.

With this three-year partnership, our ambition is to decipher the biomolecular mechanism of skin aging in order to remodel the skin in a more youthful state, Couturaud explained.

She added part of the tie-in will include the development of active ingredients to help with age reverse.

Age reverse discoveries are part of a holistic approach to beauty, which involves healthy skin above all, Couturaud said.

For Augustinus Bader, the focus has always been on the convergence of beauty, health and longevity. The doctors discovery is a communication mechanism to awaken dormant stem cells that can then trigger self-healing in skin.

Rosier described Augustinus Baders creams as epigenetic, which involves changes of gene functioning but not alterations in DNA sequencing.

Our cream is all about empowering, nourishing the skin cell environments, so [they] work at their best, he said. On the biotech as well as the consumer goods side, we are working on topics about epigenetics and longevity. It could be topicals, ingestibles different things.

The audience for such products treatments is expected to expand.

In terms of luxury buying, some people are switching from objects to experience, Rosier said. Therefore, in that field of premium experience, all the topics favoring longevity or doing something that has a net-positive epigenetic impact, is a focus that we grow, because the demand for that will grow, as well. Once you have everything, what is the thing that you want? You want to age gracefully and be in as good health for as long as possible.

However, not all beauty brands will have the capability to tap into longevity, since that requires vast scientific backing.

We could try to see what discoveries in the field of longevity can be scaled into a consumer goods product, Rosier said.

Silicon Valley has been funding a lot of research in the field of longevity.

Start-ups such as Altos Labs, a biotech company focused on cellular rejuvenation programming to restore cell health and resilience, and Calico, a research and technology company delving into the biology that controls aging and life span, are helping pave the way in this nascent sector.

The segment is growing on that tech side, and this is a bleed over into beauty, Greene said.

Some skin care brands have already put longevity into their product monikers. Theres Guerlains Le Concentr de Longevit Orchide serum and Mary Cohrs Longevity and Tonicity Body Care line, both launched in 2019.

Clinique La Prairie has just introduced a range of longevity supplements, called Holistic Health, that boost the natural antiaging process from the cells up, Gibertoni said. They feature high-diversity plant-based compounds that even the healthiest of diets cant offer.

The ranges core product is Age-Defy Regeneressence and Immunity supplements, which Gibertoni said contains the next-generation longevity formulation, including antioxidant actives and vitamins.

Shiseidos highest-end line, named Future Solution LX, is touted as having an exclusive youth-prolonging ingredient.

We were more focused at the beginning of our research into the longevity of plants, said Nathalie Broussard, scientific communications director at Shiseido EMEA. This was our source of inspiration.

In 2017, the group introduced a complex of ingredients named SkinGeneCell Enmei, which helps promote skin cell longevity, into Future Solution LX products. Those are meant to boost well-balanced, global beauty, such as general radiance.

We have deep research into genes, continued Broussard, who explained Shiseido researchers had honed in on the surtuin 1 gene, which revitalizes cells and extends their life span. So the idea was to figure out how to improve its functioning to increase skin cells longevity.

The Future Solution LX line keeps evolving. Most recently, Infinite Treatment Primer SPF 30 was added to it. At yearend, the Legendary Enmei Ultimate Luminance Serum and Ultimate Renewal Cream are being updated with the Japanese herb Enmei thats cultivated in a more sustainable way.

We have demonstrated another scientific action of the extract on another longevity gene, called surtuin 2, continued Broussard.

Next, the LX Beauty Longevity Set is due to be introduced in March 2023.

As longevity becomes increasingly top of consumers minds, addressing changing psychographics is key.

As you look forward, if youd like to live longer, a lot of anxiety comes into play, said Fernando Acosta, CEO of Roc Skincare.

Some of that angst is beauty-related. According to a Roc Skincare study, with more than 600 participants from around the world, but a focus on the U.S. and France, 90 percent of women feel anxious about aging, the primary driver being appearance-related.

In China, people who are 20 years old are anxious about getting older, Acosta said.

The overall study showed 60 percent are concerned about how they look as they get older, versus just 43 percent being worried about amassing enough money to retire.

Ninety-three percent of women told us that optimism can change their life and expressed the desire to learn more about how to do this effectively, Acosta said.

Roc executives went to a team of experts, including Daisy Robinton, who holds a Ph.D. in human biology and translational medicine.

She helped us to put together this research between mental health and physical health, Acosta said.

Another expert was Deepika Chopra. She makes a link between optimism and longevity, he said, adding Michelle Henry found the relationship between optimism and skin health.

They looked at people who have radiated optimism through their careers to amplify Rocs message, and in July, the brand announced a partnership with Sarah Jessica Parker for the #LookForwardProject that is meant to change societal attitudes on aging.

The headline for me about this is that its trying to have a conversation about not covering things up, or not being apologetic about the passing of time, Parker told WWD in July.

So our mantra is to change the conversation from being anxious about aging into [one] about the joy of living, said Acosta, who explained the experts help with practical insights and other advice, found on Rocskincare.com, to anchor the project.

This is just beginning, he said. A great conversation started around the world.

Such discussions and deep-dives into longevity are just starting for the beauty industry at large.

As time goes by, the topics of health spans, epigenetics and longevity will become more and more a concern, Rosier said.

We dont know everything about longevity, added Broussard. There are a lot of mechanisms we are still trying to decipher, so of course it will open the door to new targets in cosmetics, too.

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Beauty Bets on Longevity WWD - WWD

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Analysis of the impact of success on three dimensions of sustainability in 173 countries | Scientific Reports – Nature.com

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Our study method includes the following stages: (1) framing the investigation problem, (2) examining the literature, (3) developing and verifying two hypotheses, (4) collecting data, (5) the multiple criteria examination of 173 countries by means of the Degree of Project Utility and Investment Value Assessments (INVAR) method, (6) calculating correlations between 33 indicators and the success of 173 countries, (7) building 12 regression models, (8) compiling eight Maps (of which seven are CSS Maps) visualizing national success and sustainability, (9) spatial perspective analysis, and (10) performing integrated linear regression, multi-variant design and multiple criteria analysis of national policy alternatives, in order to identify rational decisions.

This research is a quantitative study to examine the way national success affects 12 indicators of the three dimensions of sustainability in 173 countries, and uses the data from 2020, or the latest available.

As investigation methods, our CSS Maps and Models can make it easier to study interdependencies between country success and sustainability. Supplementary Section1, 4, and 5 presents our literature analysis which is carried out to gain deeper insights into our CSS Maps and Models, and to better understand their components in the worldwide research context.

The following two core hypotheses have been proposed and verified for this research:

Hypothesis 1The increasing success of a country is generally accompanied by increasing values for the three dimensions of sustainability indicators, and declines in these indicators lead to decreases in the countrys success. Improving some sustainability indicators tends to improve other sustainability indicators.

Hypothesis 2Changes in the number of countries and their traditional key indicators system do not make a very significant difference to the relative national sustainability and success values. Likewise, the boundaries of the seven country clusters discussed in this research do not excessively depend on specific traditional key systems of indicators used in their analysis.

Along with different sets of national 17 success (Supplementary Table S1) and 12 sustainability (Supplementary Table S2) indicators, the INVAR method46 (Supplementary Section2 and Fig. S1) was used to measure and map the success of the 173 countries selected as the focus for this research. The traditional statistical indicator systems defining country success and the three dimensions of sustainability are based on studies from various countries analyzed and combined. The INVAR method calculates an integrated criterion characterizing the overall success of the countries. This integrated criterion is directly proportional to the relative effect the values and weights of the given criteria make on the countrys success. The multiple-criteria INVAR analysis method has been applied to various countries, including Asian nations47, ex-Soviet states48, and a group of 169 countries49.

This research used data from the framework of variables taken from various databases and websites, including Transparency International, Global Data, Eurostat-OECD, the World Bank, Knoema, the World Health Organization, Global Finance, Freedom House, Heritage, the Global Footprint Network, Socioeconomic Data and Applications Center, Our World in Data, Climate Change Knowledge Portal (World Bank Group), and The Institute for Economics and Peace, as well as global and national statistics and publications. All 173 countries analyzed in this article are listed in matrices, along with their 17 detailed success (Supplementary Table S1) and 12 sustainability (Supplementary Table S2) indicators (systems of indicators, their numbering, values, and weights). The INVAR method46 was applied to perform multiple criteria analysis of the 173 countries, and the results are presented in Supplementary Table S1 and Figs. 2, 3, 4 and 5. We use equal and different weights of 17 indicators to calculate the deviation of priorities for the 173 countries, which stands at 5.34% (Supplementary Section2 and Fig. S2).

Along with different sets of 12 national sustainability and 17 success indicators, the INVAR method46 was used to measure and map the success of the 173 countries selected as the focus of this research. The traditional statistical indicator systems defining country success and the three dimensions of sustainability are based on studies from various countries analyzed and combined. The INVAR method calculates an integrated criterion characterizing the overall success of the countries. This integrated criterion is directly proportional to the relative effect the values and weights of the given criteria make on the countrys success.

Supplementary Table S3 shows the correlations between all measures determined by analyzing 173 countries. Supplementary Table S4 reveals the correlation coefficient matrix of the 17 success criteria for each of the 173 countries analyzed in this survey.

Along the vertical axis y we analyze seven sustainability indicators, and along the horizontal axis x we analyze the success and priority indicators (9 CSS Map dimensions). The median correlation between the survival versus self-expression values and the nine CSS Map dimensions (the x-axis and y-axis) is moderate, whereas the median correlation between the traditional versus secularrational values and the nine CSS Map dimensions is strong (Fig.1).

Tables S5-S8 show the descriptive statistics of 12 CSS Models (Supplementary Section3). Supplementary Table S8 shows the extent to which a 1% increase or decrease in success of countrys features can push sustainability indicators up or down, expressed as a percentage. Supplementary Table S8 also shows the degree to which the percentage changes of success or the values of countrys features explain or fail to explain the dispersion of sustainability indicators. These CSS Models (Supplementary Section3) show that when a countrys success increases by 1%, its 12 indicators related to the three dimensions of sustainability improve by on average 0.85% (Supplementary Table S8). Furthermore, the 17 variables of country success used in the CSS Models explain 80.8% on average of the dispersion of the three dimensions of sustainability and 98.2% of the dispersion of the country success variable (Supplementary Table S8).

An increase of 1% in a countrys success is accompanied by a 0.39%average increase in its social and environmental (0.84% on average) sustainability indicators (Supplementary Table S8). On average, the CSS Sustainability Models explain 76.3% of the dispersions among the environmental sustainability indicators, 83.4%of the dispersions among the social sustainability indicators, and 94.5% of the dispersion among economic (i.e. the gross national income per capita) sustainability indicators (Supplementary Table S8).

The study produced the eight Maps (of which seven are CSS Maps) of the World based on an analysis of 99150 countries (the 2020 InglehartWelzel Cultural Map of the World focused on 103 analogical CSS Maps countries). The two dimensions of country success on the CSS Maps are represented in a system of 17 variables (Supplementary Table S1). When a countrys success grows, its performance related to the three dimensions of sustainable development increases as well, and the eight Maps (of which seven are CSS Maps) clearly illustrate this relationship (Figs. 2, 3, 4 and 5). The CSS Maps of the World developed as part of this study are described in Supplementary Section5.

Studies from various countries and our research suggest that country success and their features (x-axis) and sustainability indicators (y-axis) are generally strongly interrelated, and move in the same direction over time. This means that successful countries also perform better on sustainability dimensions.

Stage 9 involved analysis of the spatial perspective research in place for explaining and predicting globally recognised physical, spatial, and human patterns in multiple ways. We apply 12 CSS Models, alternative design and multi-criteria analysis methods for spatial perspective analysis (Supplementary Section4).

The following additional two research objectives were set: (1) to determine the impact of a countrys success factors on sustainability metrics, and (2) to offer stakeholders recommendations regarding the strategies for improving sustainability indicators. The ways to improve sustainability indicators are determined by analysing 17 dependent variables (the main paper section Practical applications and implications, Table S9). As previously mentioned, in stage 10, national policy options have been examined by means of integrated linear regression, multi-variant design and multiple criteria analysis to identify rational decisions. Analysis of multiple alternative options and their detailed indicators, with a consideration of the existing state of the micro, meso, and macro environment, can ensure rational country success and sustainability. Below, a brief analysis of several best global practice examples of ways to identify rational policy, activities, and strategy follows. The examples presented below suggest that multiple possible alternatives must be designed, assessed against a system of micro, meso and macro indicators, and the most effective options selected to make countries more sustainable. In Isham and Jacksons14 opinion, materialistic lifestyles and values have been associated with adverse effects on human health as well as having detrimental effects on our planet. Therefore, activities and lifestyles should be identified that promote human well-being, yet which at the same time protect ecological security. Isham and Jackson14 identify optimal activities (arts and crafts, reading, sports, meditating) with high levels of human well-being and low environmental costs. It is important to estimate pollution impacts on health in order to come up with the right policies for better health outcomes. Yet, the task is challenging because economic activity can lead to worse pollution, but can also improve health outcomes in its own right37. Humidity, temperature, dispersal by the wind, and other environmental factors contribute to pollution levels. Certain fine particulates can stay in the atmosphere for days, and travel long distances to be inhaled in places far away from the source, even in other continents. Local conditions must be reflected in emissions-control policies, and the global flows of air pollutants must be taken into account6. The explanation for the phenomenon of demographic transition could be improved public health in developed countries which results in a move toward a slower life strategy38. Studies show that children from wealthier backgrounds undergo puberty later than those from poor socio-economic backgrounds. Early puberty can lead to a variety of health problems and a shorter life. By the early adult years, the effects of exposure to trauma, post-traumatic stress disorder, and other conditions can become apparent in the form of diseases related to aging9. Education is a very important factor in economic growth, and is also strongly related to health. In addition to health benefits, substantial increases in education, especially of women, and shrinking gender gaps have an important effect on the roles and status of women in society36.

The INVAR method, statistical analysis, and the CSS Maps and Models can help generate multiple policy recommendations for various stakeholders. The possibilities are as follows:

To create alternatives for ways to develop country success and sustainability, by performing countries multiple criteria and statistical analysis and identifying decisions that would be rational;

to perform quantitative and qualitative analysis of the existing data and to interpret it. The results obtained this way would prompt automatic recommendations designed for different stakeholders on ways to improve country sustainability.

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You might have glowing skin in no time by making few easy changes to your skincare routine – TDPel Media

Posted: at 10:57 pm

Skin-Friendly Life TipsThe skin is the bodys largest organ. Its layers work hard to keep us safe while it is healthy. When it is compromised, however, the skins ability to operate as an effective barrier is impaired. As a consequence, weve identified the best strategies for restoring skin health and assisting it in maintaining its protective role.You might have glowing skin in no time by making a few easy changes to your skincare routine. Your skin is a window into your body that reflects the events of your life. From acne breakouts in youth to the glowing glow of pregnancy and the sunspots of aging, your skin reflects your age as well as your health.The skin performs several jobs, making it the human bodys ultimate multitasker. Its most crucial duty is to serve as the first barrier of protection between our bodies and the outside world, shielding us from germs, viruses, pollutants, and chemical compounds that we may encounter at work or home. You can even try hydro facials. In order to understand what is a hydrafacial, you can read more. The skin regulates body temperature, fluid balance, and moisture loss. It also serves as a barrier and shock absorber, detects pain sensations to warn us of impending danger, and shields us from the suns damaging ultraviolet (UV) rays.A number of factors influence your skin. Internal factors influencing the skin include heredity, age, hormones, and diseases such as diabetes. Some are beyond your control, but there are countless external forces over which you have power.External factors such as unprotected sun exposure and washing too frequently or with too hot water can harm the skin. An unhealthy diet, stress, a lack of sleep, insufficient exercise, dehydration, smoking, and specific drugs can all influence the skins capacity to function as an efficient protective barrier.Here are some skin care recommendations from Medical News Today to help you get rid of wrinkles, have a beautiful glow, and keep your skin supple and smooth all year.

Maintain a healthy dietThere is a multibillion-dollar market dedicated to goods that claim to battle symptoms of aging and keep your skin looking its best. However, moisturizers merely penetrate the epidermis, but aging occurs at a deeper, cellular level.What you consume is just as essential as what you put on your skin. Your diet may enhance your skins health from the inside out, thus eating a healthy diet is the first step toward a clean complexion.Skin-friendly foodsHere are some foods that have been shown in studies to be skin-healthy.Antioxidant substances can be found in mangoes. These chemicals aid in the protection of skin components such as collagen. Research in mice found that eating tomatoes regularly reduced the formation of skin cancer tumors by 50% following UV radiation exposure.According to research, integrating tomato paste into your meals may help prevent sunburn. People who took 40 grams of tomato paste per day had 40% less sunburn than the control group after 10 weeks. Lycopene, the pigment that gives tomatoes their rich red color, is considered to have a role in tomato protection against UV damage.Dark chocolate contains cocoa flavanols, which may enhance the structure and function of the skin. Scientists discovered that cocoa flavanols reduced skin roughness and scaling, increased skin hydration, and supported the skins defenses against UV ray damage.Many skin advantages have been linked to green tea. Polyphenols, which are contained in green tea, have been shown to renew dying skin cells, implying that they may be effective for mending wounds or treating some skin disorders.White tea has anti-cancer and anti-aging compounds. According to one study, certain white tea components may protect the skin from oxidative stress and immune cell damage.Kale is high in lutein and zeaxanthin. Lutein and zeaxanthin may protect the skin from UV radiation and other forms of light-induced damage.Omega-3 fatty acids found in oily fish, walnuts, and pumpkin seeds, as well as oils like linseed oil and maize oil, may help reduce skin dryness and scaling. Soy may assist menopausal women with crows feet skin wrinkles at the outer corner of their eyes.You should never rely on food to protect you from the sun. Always apply sunscreen with an SPF of at least 15, seek shade between 10 a.m. and 2 p.m., and wear clothes that cover your skin and a wide-brimmed hat to protect yourself from sun exposure.

Dietary calorie restrictionReduced calorie intake slows the cellular aging process in mice, according to research. This discovery might lead to the development of an anti-aging method for human testing in the future.Scientists discovered that cutting the number of calories ingested by 35% affects cellular aging. Cutting calories slowed the cells protein manufacturers, known as ribosomes, as well as the aging process.This slower rate not only reduced ribosome creation but also provided them time to repair themselves and maintain the body working properly. has revealed that allantoin Unfortunately, this research has only been done in worms thus far. It may, however, pave the way for novel human longevity paths to be explored in the future.

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You might have glowing skin in no time by making few easy changes to your skincare routine - TDPel Media

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