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Category Archives: Transhuman News

Cancer-causing virus masters cell’s replication, immortality – Phys.Org

Posted: May 2, 2017 at 10:31 pm

May 2, 2017 by Karl Leif Bates The Epstein-Barr virus takes control of the body's immune B-cells so that it can hide in plain sight. Up to 90 percent of all adults carry the virus without consequence, but it can cause cancers of the lymph system. Credit: National Cancer Institute

Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated nine out of ten humans without causing any ill effects.

That is, until this virus causes mononucleosis in adolescents or various cancers of the lymph nodes, including Hodgkin's and non-Hodgkin's lymphomas, in immune compromised people.

In a paper appearing in the open access journal eLife, a team of researchers from Duke's School of Medicine details just how the Epstein-Barr virus manages to persist so well inside the immune system's B cells, a type of white blood cell that is normally responsible for recognizing and responding to foreign invaders.

"The challenge is that it's a really efficient pathogen," and evades the host's immune system well even when it's recognized as an invader, said Micah Luftig, an associate professor of molecular genetics and microbiology and co-author on the new study.

Luftig's team has found that with a few select chemical signals used early in the course of an infection, Epstein-Barr mimics the beginning of the B cell's normal response to an infectious agent. From within, the virus manages to ramp up the B-cell's reproduction of itself, while at the same time helping the cell resist its own self-destruct signals.

"The virus actually taps into the B cell's normal protection against apoptosis," the programmed cell death that takes B cells out of circulation, Luftig said.

Once the infection is established, Epstein-Barr prefers to hide out in what are known as "memory B cells," relatively slowly reproducing cells that circulate throughout the body. "All of this is about establishing latency," Luftig said, or the ability to hide quietly in plain sight.

Using a new technique developed elsewhere called BH3 profiling that allowed them to test the critical cellular pro- and anti-apoptosis proteins individually, the team was able to see which of these the virus was controlling and then watch the transition from an uninfected cell to the active early infection phase to the latent infection in an immortal cell. The key piece they've uncovered is a viral protein called EBNA3A which manages apoptosis resistance in infected B cells.

The risk for cancers "is largely an issue if you're immune suppressed," Luftig said. But, for example, a recent National Cancer Institute study found that children who receive organ transplants have a 200-times higher chance of getting Non-Hodgkin's Lymphoma, one of the cancers caused by Epstein-Barr.

The team thinks BH3 profiling could prove useful in guiding treatment decisions on Epstein-Barr associated cancers such as these.

Explore further: Disrupting cell's supply chain freezes cancer virus

More information: Alexander M Price et al, Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection, eLife (2017). DOI: 10.7554/eLife.22509

Journal reference: eLife

Provided by: Duke University

When the cancer-causing Epstein-Barr virus moves into a B-cell of the human immune system, it tricks the cell into rapidly making more copies of itself, each of which will carry the virus.

About 90 percent of people are infected at some time in their lives with Epstein-Barr virus (EBV), usually with no ill effects. But individuals with compromised immune systems, such as people with organ transplants or HIV ...

(HealthDay)Children given an organ transplant have a substantially higher risk of developing cancerin some cases up to 200 times higherthan the general population, a new study finds.

After an infection with the Epstein-Barr virus (EBV), the virus persists in the body throughout a person's lifetime, usually without causing any symptoms. About one third of infected teenagers and young adults nevertheless ...

Scientists at the University of Sussex, trying to uncover how the common Epstein-Barr virus causes blood cancer in adults and children, have discovered how the virus takes control of two genes involved in cancer development ...

A small, preliminary study may show promise of a new type of treatment for progressive multiple sclerosis (MS). Results from the first six people enrolled in the phase 1 study, a study designed to enroll 10 people, are being ...

Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated nine out ...

Chickens were domesticated from Asian jungle fowl around 6000 years ago. Since domestication they have acquired a number of traits that are valuable to humans, including those concerning appearance, reduced aggression and ...

Young mongooses may conceal their identityeven from their own parentsto survive.

On a research dive in 2011 off the Aegean Sea coast of the fishing village e?mealt?, Turkey, a lucky pair of graduate students bore accidental witness to a phenomenon scientists have otherwise only ever seen in the lab: ...

A hormone called FGF21 that is secreted by the liver after eating sweets may determine who has a sweet tooth and who doesn't, according to a study in Cell Metabolism published May 2. Researchers at the Novo Nordisk Foundation ...

William Shakespeare wrote with a quill, Helen Keller liked her typewriter, and the oval squid prefers to use its body, when it comes to expressing love. But unlike these famous authors, the romanticisms of Sepioteuthis lessoniana ...

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An Important Voice Dr. Roland Pattillo’s Work Led to Henrietta Lacks’ Immortality – The Milwaukee Community Journal

Posted: at 10:31 pm


The Milwaukee Community Journal
An Important Voice Dr. Roland Pattillo's Work Led to Henrietta Lacks' Immortality
The Milwaukee Community Journal
After medical school, Dr. Pattillo completed his fellowship training at Johns Hopkins University School of Medicine and Harvard Medical School. At Johns Hopkins, Dr. Pattillo trained with George Gey, MD, who in 1951 cultured the first immortalized cell ...

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Steve Hansen: What do escort services and universities have in common? – Lodi News-Sentinel

Posted: at 10:31 pm

Question: What do shady escort services and universities have in common?

Answer: Theyll both love you if you give them enough money.

No kidding. Schools of higher education have been known to name benches, buildings, hospitals even entire schools after their generous donors. Solicitations just seem to come with the academic territory.

Take my old alma mater, for example. I used to get letters from the alumni association on a regular basis. But one day, a note arrived saying they were sick of me ignoring requests for panhandled funds. It included a threat that if I slighted the association one more time, I would never hear from them again.

These guys werent fooling around. Its been years, and theyve kept their word.

For all I know, failing to pay my fair share in donations may cause the school to deny they ever knew me. Its good I dont need proof of a degree to write for a living just a good seventh grade home-schooled education.

You dont see too many things at colleges and universities named after newspaper columnists these days. Besides, based on what we get paid, we couldnt donate enough to get a paper plaque on a well-used fire hydrant frequented by a roving Rottweiler.

But thats OK. We work for the love of writing and readily reject frivolous fame not that I wouldnt mind buying a medical or law school someday. At least I could count on free advice from the deans. That could come in quite handily in todays era of insurance capitation and litigious lunacy.

It wasnt always this way. There were times in the past when schools named their halls and laboratories (not to be confused with lavatories) after people who had actually contributed something to the betterment of humanity. I dont consider making a killing in real estate foreclosures or an instant dotcom millionaire necessarily fits that category.

Theres the Albert Einstein College of Medicine (he didnt make enough money to buy a haircut), the Thurgood Marshall School of Law, and Lincoln University.

As of this date, no one has been able to remove these names and replace them with his or (rarely) her own, using an eight-figure cashiers check. But there is still opportunity, and schools are always looking for ways to fill their coffers. Its just a matter of time until the price is right.

Now Im not trying to be critical here. Lord knows we all have to make a buck, and academia is no exception.

Perhaps Im just envious, but I have used other options to try and keep my name in play for posterity.

For example, a few years ago, my wife and I donated a good sum of money to a public zoo in order to build a mountain lion exhibit.

But our quest for perpetuity was not to be. The mountain lions have gone to kitty heaven, the exhibit has become overgrown with native grasses and our bronze plaque is nowhere to be found (probably oxidizing under those native grasses somewhere).

We also are regular contributors to an automobile museum and sponsor a 1937 Cord. But the last time we were there, our plaque was gone, our car was gone and soon, so were we.

But before we left, I asked the management: What happened to our Cord?

Oh, was the reply. We loaned it to a museum in Indiana. It should be back in a couple of years. Hope you dont mind.

As you can see, buying fame and immortality for us little guys is not an easy task. Without a big checkbook, we just fade into the sunset with the rest of the rubes.

But there is always optimism. Ill keep writing my column and hope that someday, my genius will be discovered, and a multimillion-dollar book contract will be in my high-five hardened little hands.

Then I can look forward to that glorious day when my everlasting name will shine in splendor over the entrance of a prominent university washroom too!

Steve Hansen is a Lodi writer.

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The Techno-Libertarians Praying for Dystopia – Yahoo Tech

Posted: at 10:30 pm

If you believed that the necessary next step in our species evolution was to merge with artificial superintelligence, and to thereby transcend our animal condition and become immortal, what effect might that have on your politics?

This is not an entirely abstract question. There are people who believe that the future of our species involves shedding our humanity in a marriage with AI; this is known as transhumanism, and it has not unreasonably been called a new tech religion. Though the movement has no explicit political affiliations, it tends, for reasons that are probably self-explanatory, to draw a disproportionate number of Silicon Valley libertarians. And the cluster of ideas at its center that the progress of technology will inevitably render good ol Homo sapiens obsolete; that intelligence, pure computational power, is to be pursued above all other values has exerted a powerful attraction on a small group of futurists whose extreme investment in techno-libertarianism has pushed them over an event horizon into a form of right-wing authoritarianism it might be useful to regard as Dark Transhumanism.

The English critical theorist turned far-right cult thinker Nick Land is usefully representative of this intellectual tendency. Although he has never identified as a transhumanist, his ideas are infused with the movements delirious faith in the coming merger of humans and machines. His current political vision, which he has given the flamboyantly portentous title the Dark Enlightenment, is one in which the programmer elite and their ingenious technologies rule the world. Increasingly, he wrote in 2014, there are only two basic human types populating this planet. There are autistic nerds, who alone are capable of participating effectively in the advanced technological processes that characterize the emerging economy, and there is everybody else. Many transhumanists would be inclined to reject the political implications of Lands futurism, but his vision is only really a darker, more explicitly fascistic rendering of the kind of thinking you find in the work of the futurist Ray Kurzweil, or for that matter Wired founder Kevin Kelly, who believes that we humans are the reproductive organs of technology.

For Dark Transhumanists, as for the neo-reactionaries from whom they take their cues, egalitarianism is inherently incompatible with any posthuman future. Take Peter Thiel, the Facebook investor who in a 2009 essay for the libertarian journal Cato Unbound announced, I no longer believe that freedom and democracy are compatible. Asked in a 2011 New Yorker profile whether the kinds of life extension technologies he was investing in might exacerbate already grotesque levels of social inequality, Thiels response offered a glimpse into the ethical simple-mindedness of his techno-libertarianism: Probably the most extreme form of inequality, he said, is between people who are alive and people who are dead.

Or theres Michael Anissimov, a former media director at the Machine Intelligence Research Institute a think tank in Berkeley devoted to preventing superhuman AI from destroying humanity who has in recent years basically cornered the white-supremacySingularity crossover market.

Anissimov, with his weird synthesis of 19th-century racist pseudoscience and fantastical futurism, is a Dark Transhumanist par excellence. In a 2013 interview, he outlined how the cultural ingraining of the notion that were all created equal left us unprepared for a future of technologically enhanced beings. There are, he insists, already significant disparities in intelligence between existing races. Transhuman technologies, he says, would mean situations in which people could be lording over one another in a way that was never possible before in history. Its pretty clear that Anissimov sees nothing to fear in such a future, confident as he is that it will be people like him doing the lording. Despite being approvingly quoted in Kurzweils The Singularity Is Near, Anissimov is these days something of a pariah from the transhumanist movement. But it is worth asking whether his specific mutation of transhumanist thinking is troubling not just because of its extremist right-wing implications, but because it magnifies illiberal, radically elitist tendencies that are inherent in transhumanism itself. Although its intellectual and spiritual roots can be traced back as far as the gnostics, transhumanism is a fever dream of contemporary technocapitalism, and it is nave to suppose that the technological enhancements it conjures would do anything but exacerbate already existing social inequalities.

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There is, in transhumanism itself, a strain of old-timey historical romanticism: a sense of history as an inexorable progress toward a teleological vanishing point, where all human meaning is subsumed and obliterated by a godlike technology. This belief that flesh is a dead format, and that our future or that, at least, of a technological elect involves a final merger with machines is one that interlocks in sinister ways with the view of democracy as a failed and outmoded institution. Transhumanists view the human body as a system in need of technological disruption and ultimate transcendence, and neo-reaction views the state, the body politic, in much the same manner. Seen in a certain way, this is a mind-set a reductionist understanding of the world as a hackable system inherent in the culture of computer science. The flesh is weak, and democracy is entropic; both are subject to forces of decay, to human inefficiencies and failings. As eccentric and fringe a phenomenon as Dark Transhumanism may be, its usefully viewed in this sense as an extrapolation of tendencies inherent in the mainstream techno-capitalism of Silicon Valley.

*A version of this article appears in the May 1, 2017, issue of New York Magazine.

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Trump keeps praising international strongmen, alarming human rights advocates – Washington Post

Posted: at 10:30 pm

Its no longer just Vladimir Putin.

As he settles into office, President Trumps affection for totalitarian leaders has grown beyond Russias president to include strongmen around the globe.

Egyptian President Abdel Fatah al-Sissi has had his opponents gunned down, but Trump praised him for doing a fantastic job. Thailands prime minister, Prayuth Chan-ocha, is a junta chief whose military jailed dissidents after taking power in a coup, yet Trump offered to meet with him at the White House. Turkish President Recep Tayyip Erdogan has eroded basic freedoms, but after a recent political victory, he got a congratulatory call from Trump.

Then theres the case of Philippine President Rodrigo Duterte. He is accused of presiding over the extrajudicial killing of thousands of drug dealers and users. And in response to U.S. criticism of his human rights record last year, he said President Barack Obama can go to hell.

Yet on Sunday, in what the White House characterized as a very friendly conversation, Trump invited Duterte to Washington for an official visit.

(Sarah Parnass/The Washington Post)

In an undeniable shift in American foreign policy, Trump is cultivating authoritarian leaders, one after another, in an effort to reset relations following an era of ostracism and public shaming by Obama and his predecessors.

For instance, it has become an almost daily occurrence for Trump to gush about Chinese President Xi Jinping since their Mar-a-Lago summit last month. Trump has called Xi a very good man, highly respected and a gentleman, as he tries to persuade Xi to convince North Korea that it should scale back or give up its pursuit of nuclear weapons.

Trumps praise is not limited to potential U.S. allies. Even as North Korean leader Kim Jong Un ratchets up his provocations, Trump called Kim a smart cookie in a CBS News interview over the weekend. On Monday, Trump told Bloomberg News he would be honored to personally meet with Kim under the right circumstances.

[Trump takes a selective approach to the promotion of human rights]

Every American president since at least the 1970s has used his office at least occasionally to champion human rights and democratic values around the world. Yet, so far at least, Trump has willingly turned a blind eye to dictators records of brutality and oppression in hopes that those leaders might become his partners in isolating North Korea or fighting terrorism.

Indeed, in his first 102 days in office, Trump has neither delivered substantive remarks nor taken action supporting democracy movements or condemning human rights abuses, other than the missile strike he authorized on Syria after President Bashar al-Assad allegedly used chemical weapons against his own people.

He doesnt even pretend to utter the words, said Michael McFaul, a U.S. ambassador to Russia under Obama. Small-d democrats all over the world are incredibly despondent right now about Donald Trump and thats true in China, in Iran, in Egypt, in Russia. They feel like the leader of the free world is absent.

A tipping point for many Trump critics was his invitation to Duterte to visit the White House. Sen. Benjamin L. Cardin (Md.), the ranking Democrat on the Senate Foreign Relations Committee, said he was deeply disturbed by Trumps cavalier invitation and called on him to rescind it.

This is a man who has boasted publicly about killing his own citizens, Cardin said of Duterte in a statement. The United States is unique in the world because our values respect for human rights, respect for the rule of law are our interests. Ignoring human rights will not advance U.S. interests in the Philippines or any place else. Just the opposite.

Yet Trumps advisers said the presidents silence on human rights matters is purposeful, part of a grand strategy to rebuild alliances or create new ones. Trumps outreach is designed to isolate North Korea in the Asia-Pacific region and to build coalitions to defeat the Islamic State in the Middle East and North Africa, senior administration officials said.

Inside the Trump White House, the thinking goes that if mending bridges with a country such as the Philippines historically a treaty ally whose relationship with the United States deteriorated as Duterte gravitated toward China means covering up or even ignoring concerns like human rights, then so be it.

The United States has a limited ability to direct things, said Michael Anton, the National Security Councils director of strategic communications. We cant force these countries to behave certain ways. We can apply pressure, but if the alternative is not talking, how effective would it be if we had no relationships? If you walk away from relationships, you cant make any progress.

Anton explained that Trump is trying to balance interests. He said the decision to invite Duterte to the White House a symbolic gesture that gives credibility to the autocrats rule was agreed to by most of Trumps advisers.

Its not binary, he said. Its not that you care about human rights so you cant have a relationship with the Philippines, or if you have a relationship with the Philippines you dont care about human rights.

Senate Foreign Relations Committee Chairman Bob Corker (R-Tenn.) described the Trump strategy as establishing commonality with offending nations before publicly chastising them for offenses.

Their approach is to obviously continue to hold up the values that we have here in America, Corker said in a recent interview. But their approach is to build some commonality never let go of that as an American cause, but to work on it in ways where they achieve a result, and to not go in on the front end.

White House officials cite the release last month of Aya Hijazi an Egyptian American charity worker who had been imprisoned in Cairo for three years amid Sissis brutal crackdown on civil society as evidence that their strategy is paying dividends.

Trump and his aides worked for several weeks with Sissi and his government to secure Hijazis freedom. The Obama administration had pressed unsuccessfully for her release, but once Trump moved to reset U.S. relations with Egypt by embracing Sissi at the White House, Egypts posture changed.

[Freed Egyptian American prisoner returns home following Trumps intervention]

Tom Malinowski, assistant secretary of state for human rights and democracy under Obama, said Trump appears to be living up to his campaign promise.

The whole idea of America First is that were not trying to make the world better, Malinowski said. Were trying to protect the homeland and the domestic economy, and the rest is all cutting deals with whoever is willing to cut deals with us. Theres not much room in that equation for standing up for the rights, freedoms and well-being of other people.

Human rights activists are concerned that Trump is condoning the actions of dictators when he is warm to them or extends invitations to visit.

Inviting these men to the White House in effect places the United States seal of approval on their heinous actions, said Rob Berschinski, senior vice president at Human Rights First. He went on to say, Nothing excuses President Trumps clear inclination to reward mass murderers and torturers with undeserved honors.

Asked at the daily White House press briefing whether Trump had a thing for totalitarian leaders, press secretary Sean Spicer suggested he was cultivating such leaders with the explicit aim of weakening North Korea.

The president clearly, as I said, understands the threat that North Korea poses, Spicer said. Having someone with the potential nuclear capability to strike another country and potentially our country at some point in the future is something that the president takes very seriously.

But McFaul posited that the Trump administration may be naive in calculating that personal outreach and warm praise will persuade authoritarian leaders to support U.S. interests.

The converse of that is that these leaders are taking him for a ride, McFaul said. He tends to over-personalize relationships between states. He says Chinas raping us, then he meets President Xi and suddenly hes this wise man with whom he has a good chemistry. I hope this will produce outcomes that are good for us, but right now its producing outcomes that are good for China.

Karen DeYoung contributed to this report.

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Transhumanism Is Not an Alt-Right Conspiracy! – Reason (blog)

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Wavebreakmedia/DreamstimeAs part of its special issue on the so-called alt-right, New York Magazine has published an especially dim-witted article attacking transhumanism entitled, "Techno-Libertarians Praying for Dystopia." The author Mark O'Connell begins by going after Silicon Valley venture capitalist and wrong-headed Trump-supporter Peter Thiel who also happens to have some interest in how the technological Singularity may unfold. Thiel has made no secret about the fact that he has long had "this really strong sense that death was a terrible, terrible thing." Thus he finances researchers who hope to develop anti-aging technologies and think tanks that try to foresee the consequences of succeeding at that goal. Fine.

To illustrate Thiel's evil intentions, O'Connell points to his 2009 assertion, "I no longer believe that freedom and democracy are compatible." As further evidence of political depravity, he cites Thiel's 2011 observation, "Probably the most extreme form of inequality is between people who are alive and people who are dead." Based on these statements, O'Connell accuses Thiel of "ethical simple-mindedness." Really? Is it not more ethically simple-minded to believe that democratic authoritarianism cannot run roughshod over minority rights or that ensuring that everybody is equally diseased, disabled, and dead is somehow the height of moral probity.

O'Connell then notes that other Silicon Valley "libertarians" share Thiel's interest in human enhancement (and not only those who reside in purlieus of Palo Alto do too). Apparently, for O'Connell, the desire for ageless bodies and enhanced minds necessarily amounts to a rightwing conspiracy. As evidence for his claim that transhumanism is a manifestation of the alt-right, O'Connell digs up a couple of oddballs who've hung around the fringes of transhumanism who now call themselves neo-reactionaries. Of course, anybody can apply the labels libertarian and transhumanist to themselves with malice aforethought. Remember how progressives stole the term "liberal" back in the day. Once O'Connell has made the old guilt-by-association rhetorical move, he does admit that one of his two exemplars of supposedly alt-right transhumanism is "these days something of a pariah from the transhumanist movement." Indeed.

Transhumanism is a big tent. For example, my sometime intellectual sparring partner James Hughes, who is former executive director of the World Transhumanist Association, is a fierce social democrat and author of Citizen Cyborg: Why Democratic Societies Must Respond to the Redesigned Human of the Future (2005). In his Transhumanist Values manifesto, Oxford philosopher Nick Bostrom argues for wide access to enhancement technologies:

The full realization of the core transhumanist value requires that, ideally, everybody should have the opportunity to become posthuman. It would be sub-optimal if the opportunity to become posthuman were restricted to a tiny elite.

There are many reasons for supporting wide access: to reduce inequality; because it would be a fairer arrangement; to express solidarity and respect for fellow humans; to help gain support for the transhumanist project; to increase the chances that you will get the opportunity to become posthuman; to increase the chances that those you care about can become posthuman; because it might increase the range of the posthuman realm that gets explored; and to alleviate human suffering on as wide a scale as possible.

The wide access requirement underlies the moral urgency of the transhumanist vision. Wide access does not argue for holding back. On the contrary, other things being equal, it is an argument for moving forward as quickly as possible. 150,000 human beings on our planet die every day, without having had any access to the anticipated enhancement technologies that will make it possible to become posthuman. The sooner this technology develops, the fewer people will have died without access.

Is transhumanism some kind of ultimate threat to humanity? Not all. Last year I explained in the Washington Post:

One crowning achievement of Enlightenment humanism is the principle of tolerance, of putting up with people who look different, talk differently, worship differently and live differently than we do. In the future, our descendants may not all be unenhanced Homo sapiens, but they will still be moral beings who can be held accountable for their actions. There is no a priori reason to think that the same liberal political and moral principles that apply to diverse human beings today would not apply to relations among future humans and transhumans.

The highest expression of human nature and dignity is to strive to overcome the limitations imposed on us by our genes, our evolution and our environment. Future generations will look back at the beginning of the 21st century and be astonished that some well-meaning and intelligent people actually wanted to stop bio-nano-infotech research and deployment just to protect their cramped and limited vision of human nature. If transhumanism is allowed to progress, I predict that our descendants will look back and thank us for making their world of longer, healthier and abler lives possible.

Does that sound like anyone is praying for a dystopia?

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James Scully’s radical idea for the fashion industry: Treat models like human beings – Washington Post

Posted: at 10:30 pm

James Scully did not intend to become the public scold of a global fashion industry one that views models as interchangeable widgets, that strong-arms them into unhealthy weight-loss regimens and insists on referring to them as girls. Nonetheless the veteran casting director has emerged as one of the most vocal agitators for change. He wants the fashion industry to treat models like human beings rather than commodities.

In February, several models came to him complaining about their treatment at an audition for the fall 2017 Balenciaga runway show the kind of prestigious booking that could pave a young models way in the business. Not only had some 150 hopefuls waited hours for the chance to be one of 47 chosen to walk in the show, they also had been left languishing for hours in an unlit stairwell while the casting directors went out for lunch.

Incensed, Scully took to Instagram to call out the Balenciaga team. But he wasnt done yet. In that same post, Scully claimed that representatives of the French fashion house Lanvin told model agencies not to send black women to its auditions. Finally, he voiced his suspicions that underage models were being booked in Paris, where 16 is the standard minimum.

I made the post out of personal outrage, Scully says a month later.

His alert led to apologies from Balenciaga, as well as denials and explanations from Lanvin and the casting directors accused of wrongdoing. But more than anything, Scullys words a rather modest call to arms, on the face of it managed to add fuel to an ongoing conversation about the often unprofessional, disorganized and offensive treatment of models by their own industry.

The frock trade has always been far grittier and seamier than its glossy trappings would suggest. There have been dramatic examples of drug abuse, deaths from eating disorders and sexual misconduct. But there are far more stories of mistreatment by omission or disregard. Models are expected to wait hours at an audition. They have fittings that last until the wee hours of the morning for which they receive no overtime pay. Sometimes they are paid for their services in clothes, not currency. They can wind up as nearly indentured servants working to pay off debts to their agencies.

And often designers and their staffs even fail to recognize that models need water as became clear during Kanye Wests presentation on Roosevelt Island last summer, when unpaid models collapsed in the September heat.

Im trying to make people realize the human cost of this behavior, Scully says. We have normalized it and become desensitized to it.

The Council of Fashion Designers of America offers some guidance all of it optional about providing food and water backstage and at long fittings, about not booking unhealthily thin models, about striving for diversity. The New York legislature passed a law in 2013 giving models younger than 18 protections similar to those that govern child actors, such as limits on work hours and regulations regarding pay.

But there are loopholes. And models 18 and older are essentially on their own, says Sara Ziff, who in 2012 founded the Model Alliance, an advocacy organization for models working in the United States.

I make sure parents understand that their child might be pressured to miss school, says Ziff, a former model. There are a lot of adult pressures that come with working in the industry at a young age.

In the past, models were typically in their 20s, with a sense of how the industry worked, by the time their careers gained traction. Now its all accelerated, Scully says. Todays models are being asked to do a womans job, and theyre kids.

The potential for abuse has grown with practices such as street casting, in which designers invite everyone from friends to their favorite bartender to participate in a show. The philosophy suggests that almost anyone can be a model at least for a few hours. The churn of fast fashion means that not just clothes are disposable; people are, too.

Girls are seeing this big dream world through social media. They think they can be a model and dont realize what theyre getting into. The turnaround now is so fast; its almost like trafficking, says Scully, who sits on the Model Alliance advisory board. Theyre pulled in and traumatized and then spit back out.

Scully, 52, is tall and slim with neatly trimmed salt-and-pepper hair, a jutting jaw, and a resting expression that is pleasantly somber supporting-actor handsome. His Manhattan apartment is filled with calming earth tones and nubby textures. He is the picture of earthy serenity by way of Architectural Digest.

But when he speaks, its at full gallop, his voice filled with the agita of someone whose childhood fantasy-come-true has gone bad.

One of 10 children in a working-class family, he spent his early childhood in South Amboy, N.J., a small city about an hour outside Manhattan that was almost all white and largely Catholic. It was the smallest town with the most bars, he says. Id never been around an Asian person. I didnt know what a Jewish person was.

He was transfixed by acting after an aunt took him to see Pippin on Broadway, but he loved fashion, too, thanks to an older sister with a stash of Cosmopolitan magazines. He enrolled at the Laboratory Institute of Merchandising (LIM), where he took a class taught by Audrey Smaltz, a former host of Ebony Fashion Fair and founder of the team of backstage dressers and assistants called the Ground Crew. Scully became her intern.

His freelance work with her helped pay his way through school until he was distracted by jobs in retail and nightlife. His grades fell, he lost his scholarship and dropped out. He got a job at the influential fashion boutique Charivari, later worked for the production company Kevin Krier & Associates, and then Harpers Bazaar. Scullys career helped him see the fashion industry from virtually every angle.

Hes been a part of fashion shows since the early 90s, and hes seen a lot in that time, Smaltz says. Hes seen all thats happened and how its changed. Its not nice.

Smaltz recalls when a runway show featured 10 to 15 professional models, and each would make three or four changes in a single show. Today, a show hires 50 women. Mostly, anonymous. No clothing changes.

How can you pay all those models? They try to pay the models in clothes. Smaltz says. You dont need anyone with experience. Theyre like robots. ... Some directors tell the girls: Do not smile. Do not clap. Its one model after another. Its a human conveyor belt.

Scullys foray into activism began in the mid-2000s, but the seeds had been planted earlier. As a teenager, his vision of fashion was shaped by images of the multicultural aesthetic of Saint Laurent and Halston in the 1970s an ideal he continued to carry into his career.

He went on to work on some of the most influential runway shows of the late 1990s, including those mounted by Tom Ford for Gucci and Yves Saint Laurent, whose casting was particularly diverse. Fords shows helped turn the Ethiopian-born model Liya Kebede into a star. In 2003, she became one of the faces of Estee Lauder the first black model to represent the beauty brand.

But the prejudices Kebede faced along the way exasperated Scully. A few years later, after taking time away from the industry, he joined activist Bethann Hardison and models Naomi Campbell and Iman in industry town halls, panel discussions and a media blitz to highlight the lack of black and brown models on the runway. Hardison, a former model and agent, worked to mentor more women of color, and men. Scully pushed to cast more of them in shows.

[Once Again, White Is the New White]

He speaks his mind. Thats who he is, Smaltz says. I just thought, Good for you, Scully. Take care of these young girls.

In May, he will be honored by the Black Alumni of Pratt Institute for his efforts.

In the winter of 2016, Scully delivered an impassioned talk at a Business of Fashion conference in Europe about labor practices that include bullying young women and treating puberty like a career-killer.

His February Instagram post, with more than 9,700 likes, received overwhelmingly positive feedback. Change is on the way thanks to you, wrote model Karolina Wallace.

It gives me a lot of hope to know that there is someone like you fighting for better treatment of models, wrote Gwen Van Meir, a young model. I once [was] in Milan, waited at a casting for almost four hours in the hot sun, with no water available. ... It seemed like a lot of the models were afraid to say anything.

Over the years, the very nature of what it means to be a model has shifted, from one of performer and experienced professional to that of an anonymous, prepubescent-looking mannequin. Only a few savvy young women of this era Gigi Hadid, Karlie Kloss, Kendall Jenner have successfully positioned themselves as full-fledged personalities with the potential for professional longevity. Thats largely thanks to their diligent off-the-clock efforts on social media.

But models have few work protections. Theyre not unionized. Financial agreements with agencies can be opaque. Pressure to lose weight is not just a medical concern but also a labor issue, says Ziff of the Model Alliance.

I think that many of the problems James called out models waiting an inordinate amount of time, working through the night, not having breaks all of that is a symptom of a bigger problem, Ziff says. And thats a power imbalance.

Modeling has always been unregulated. And a models career was always relatively short and reliant on a certain amount of good timing and genetics. But there was a code of ethics and on some human level, you did care about models, Scully says.

I sit and I have to do massive castings with 600 girls a season, Scully says. Im bleary-eyed. I have no idea who I saw.

Now its really about being clothes hangers, he says. Theyre disposable and replaceable.

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Elon Musk Just Unveiled His Plans for the Future in a Ted Talk – Futurism

Posted: at 10:29 pm

In Brief

This past weekend, the tech world was abuzz with the most recent developments discussed by mega-CEO Elon Musk at the annual TED conference in Vancouver.

During his talk, Musk updated the crowd on some of his most anticipated projects, including his future vision for The Boring Company, the all-electric semi-truck from Tesla, as well as developments regarding the Gigafactory. This progress was already covered over the weekend, but now we have a video of his entire talk.

Musk dazzled audiences with a video presentationthat displayed a network of underground tunnels. Vehicles were skirted through the tunnels at high speeds on proprietary platforms, dubbed skates. During the talk, Musk stated that Theres no real limit to how many levels of tunnels you can have. The deepest mines are much deeper than the tallest buildings are tall, suggesting that his plans for the company are titanic in scale.

Musk also gave the audience a glimpse into Teslas new heavy-duty electric truck. The all-electric vehicle is said to be capable of rivaling or surpassing sports cars in terms of performance.

He also, of course, discussed SpaceX and his vision of putting humans on Mars.

To the uninitiated, Musk can look a lot like a Wizard of Oz type figure. However, unlike the wizard, Musks magic is being backed up by both action andverifiable science.

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Researchers Have Started a Trial to Refreeze the Arctic – Futurism – Futurism

Posted: at 10:29 pm

In BriefA spin-off of an ambitious idea to refreeze the Arctic usingmachines is about to get a trial run in Switzerland where a team ofresearchers plan to add ice to a glacier in the Alps using snowmachines. Snow Machines

One of the strongest and most obvious indications of global warming is the receding polar ice caps, most specifically, the Arctic sheets. In February of this year, scientists brought up a peculiar solutionfor combating melting ice caps: refreezing them. Now, this seemingly outlandish idea is about to get a test run in Switzerland.

The pilot Swiss plan is similar to the proposed Arctic solution, except instead of entire ice caps, the target would be a small, artificial glacierat the foot of the Diavolezzafirn glacier. Whilethe Arctic plan proposed the use of wind-powered pumpsto spew water on top of ice, this mini-version of the project willuse snow machines to preserve the glacier over the summer by covering it with artificially created snow.

We have to carry the glacier through the summer, Utrecht University researcher Johannes Oerlemans explained toNew Scientist.

This ambitious plan is one of several ideas to combat global warming, which range from decreasing fossil fuel dependence to even geoengineering the planet.

If it works, the next step would be to try it out on the larger Morteratsch glacier in the eastern Swiss Alps, a plan Oerlemans recently presented at an annual meeting of the European Geosciences Union in Vienna, Austria. Rising temperatures due to global warming have caused this vast valley glacier to recede at an alarming rate of 30 to 40 meters (98 to 131 feet) each year, according to a New Scientist report.

Oerlemans and his colleagues, however, dont just plan to keep the Swiss glaciers from receding. They want to grow them back, and 4,000 snow machines might just do the trick. In principle, even the snout could grow back, said Oerlemans. Within 20 years, he concluded, the glacier might be able to grow by 800 meters (2,625 feet) if researchers blow just a few centimeters of artificial snow over a 0.5 square kilometer (.19 sqaure mile) plateau each summer to give it cover.

In the case of the Arctic, however, it wouldnt be that simple. The area is huge, roughly 107square kilometers(3.8 million square miles), and the plan to refreeze it with water pump would require a hugeinvestment. If it worked, however, an extra meter of sea ice could be added in just one year, according to the Arctic plan, winding the ice cap clock back by 17 years.

Buying that sort of time might just be worth the effort required to put seemingly impossible ideas to fight climate change into action, and this smaller project in Switzerland could providethe confidence needed to give them a shot.

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A World First Fusion Reactor Just Created Its First Plasma – Futurism

Posted: at 10:29 pm

Achieving First Plasma

After being turned on for the first time, the UKs newest fusion reactor has achieved first plasma. This simply means that the reactor was able to successfully generate a molten mass of electrically-charged gas plasma inside its core.

Called the ST40, the reactor was constructed by Tokamak Energy, one of the leading private fusion energy companies in the world. The company was founded in 2009 with the express purpose of designing and developing small fusion reactors to introduce fusion power into the grid by 2030.

Now that the ST40 is running, the company will commission and install the complete set of magnetic coils needed to reach fusion temperatures. The ST40 should be creating a plasma temperature as hot as the center of the Sun 15 million degrees Celsius (27 million degrees Fahrenheit) by Autumn 2017.

By 2018, the ST40 will produce plasma temperatures of 100 million degrees Celsius (180 million degrees Fahrenheit), another record-breaker for a privately owned and funded fusion reactor. That temperature threshold is important, as it is the minimum temperature for inducing the controlled fusion reaction. Assuming the ST40 succeeds, it will prove that its novel designcan produce commercially viable fusion power.

Tokamak Energy CEO David Kingham commented in a press release: Today is an important day for fusion energy development in the UK, and the world. We are unveiling the first world-class controlled fusion device to have been designed, built, and operated by a private venture. The ST40 is a machine that will show fusion temperatures 100 million degrees are possible in compact, cost-effective reactors. This will allow fusion power to be achieved in years, not decades.

Nuclear fusion is a potentially revolutionary power source. It is the same process that fuels stars like our Sun, and could produce a potentially limitless supply of clean energy without producing dirty waste or any significant amount of carbon emissions. In contrast to nuclear fission, the atom splitting that todays nuclear reactors engage in, nuclear fusion requires salt and water, and involves fusing atoms together. Its primary waste product is helium. Its easy to see why scientists have tried to figure out how to achieve this here on Earth, but thus far its been elusive.

The journey toward fusion energy undertaken by Tokamak Energy is planned in the short-term and moving quickly; the company has already achieved its half-way goal for fusion power delivery. Their ultimate targets include producing the first electricity using the ST40 by 2025 and producing commercially viable fusion power by 2030.

Kingham remarked in the press release: We will still need significant investment, many academic and industrial collaborations, dedicated and creative engineers and scientists, and an excellent supply chain. Our approach continues to be to break the journey down into a series of engineering challenges, raising additional investment on reaching each new milestone.

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