Page 1,780«..1020..1,7791,7801,7811,782..1,7901,800..»

Category Archives: Transhuman News

Next Generation of GMOs Escapes Regulation – EcoWatch

Posted: June 1, 2017 at 10:15 pm

Twenty years ago, proponents of genetic engineering promised that GMO foods would increase yields, reduce pesticides, produce nutritious foods and help feed the world. Today, those promises have fallen far short as the majority of GMO crops are engineered to withstand sprays of Roundup herbicide, which is increasingly documented as a risk to human health.

Now, new genetic engineering technologies such as synthetic biology and gene editing are being hailed with the same promises of revolutionizing food production, medicine, fuels, textiles and other areas.

But a closer look at this next generation or "GMOs 2.0" technologies reveals possibly even greater risks than existing GMO technology with possible human health risks and negative impacts on farming communities worldwide, among other unintended consequences. And while products developed using current genetic engineering methods are regulated by the U.S. government, GMOs 2.0 products are entering the market with few or no regulations.

Synthetic Biology: Extreme Genetic Engineering

While traditional genetic engineering involves inserting genes from one species into another, GMOs 2.0 technologies like synthetic biology aim to create life from scratch with computer-synthesized DNA.

"Genetic engineering has moved on from the first generation GMO crops," said Jim Thomas, program director at the ETC Group, a non-profit advocacy group that tracks the new GMO technologies. "There are different ways to genetically engineer an organism by creating synthetic DNA or editing DNA."

The ETC Group describes synthetic biology or "extreme genetic engineering" as "the design and construction of new biological parts, devices and systems that do not exist in the natural world and also the redesigning of existing biological systems to perform specific tasks."

"Synthetic biology is about synthesizing genetic sequences, designing them increasingly from scratch as if they were parts to put together in a particular way to get a predicted outcome," Thomas said.

The synthetic biology process involves altering the DNA of microorganisms such as algae, bacteria and yeast so they produce compounds like flavors and fragrances that previously have been extracted from plants. Scientists and software engineers are altering the DNA of existing microorganisms and designing new ones.

Synthetic biology companies are producing a wide range of compounds for food, pharmaceutical, fuel and industrial use. Evolva has created a synthetic biology form of vanillin, an alternative to natural vanilla extract. Perfect Day has engineered yeast cells to produce proteins similar to those found in cow's milk with the aim of producing vegan milk. Impossible Foods engineered heme, a molecule that makes meat sizzle and look pink for the company's meatless Impossible Burger. According to the ETC Group, there are some 350 synthetic biology products on the market or in development.

The claimed benefits of synthetic biology products such as flavors and fragrances are that they can be produced in greater and more consistent quantities and at lower prices than crop-based plant materials that are subject to climate conditions, crop failures and transportation logistics.

CRISPR Gene Editing

Another GMOs 2.0 technology is a gene editing method called CRISPR. This enables scientists to edit parts of the genome by removing, adding or altering sections of the DNA. The aim is to activate or deactivate genes to produce a desired effect. Proponents say CRISPR has the potential to treat illnesses that have a genetic basis such as cancer, sickle cell anemia, hepatitis B or high cholesterol.

GMO seed companies are using CRISPR to develop new plant varieties. Cibus used the technique to develop an herbicide tolerant canola. Pioneer Hi-Bred is developing waxy corn hybrids with high starch content for food and non-food uses. Monsanto recently announced it was licensing the CRISPR technology to develop new seed varieties.

Proponents say CRISPR is "the simplest, most versatile and precise method of genetic manipulation."

"It's a lot more precise in that it targets a specific gene in the genome where it exists while genetic engineering involves inserting a gene at random in the genome, which could disrupt the functioning of other genes," said Jim Orf, professor emeritus, plant breeding and genetics at the University of Minnesota.

But Thomas said scientists are seeing unintended effects using CRISPR. In fact he said "some scientists are intentionally not using CRISPR because of off-target effects." Orf also admitted that the technology is not "100 percent foolproof." Dr. J. Keith Joung of Massachusetts General Hospital said there is growing evidence that CRISPR might alter regions of the genome other than the intended ones.

Technology Risks

Causing unintended consequences is one of the problems with current genetic engineering methods, and these could be even worse with GMOs 2.0 technologies, particularly synthetic biology.

"You're not just adding one gene with all the implications of that. Here you are dealing with stretches of DNA that are invented on a computer. The level of novelty and the depth of intervention are much more significant."

Synthetic biology techniques could create secondary metabolites or molecules or different levels of compounds that could have negative impacts.

An underlying problem with the techniques is that they are based on an outdated premise of how biology and nature function.

"One of the dangers with synthetic biology is that it pretends that life is a linear, predictable system that you can engineer as if you can re-engineer a car or computer and that DNA is just a code," Thomas said, "But all those metaphors are falling apart in the biological sciences."

There are also social concerns. Companies like Evolva that make synthetic biology flavors like vanillin are hurting the market for natural vanilla produced by farming communities in Madagascar.

"These companies are trying to disrupt those markets and take that value," Thomas said. "If you can produce vanillin, then you will start affecting the supply chains and livelihoods of vanilla farmers."

Natural and Non-GMO Claims

Another problem is that some synthetic biology and gene editing companies are claiming that their products are natural or even non-GMO. Cibus calls its gene-edited canola "non-transgenic." Synthetic biology companies say that even though the production organism they create is a GMO, they claim the final ingredient is non-GMO.

"They'll argue that the (GMO) production organism is a just a processing aid," Thomas said. "That's a bit like saying a cow is a processing aid for making milk."

The Non-GMO Project also disagrees.

"There is a growing attempt on the part of biotechnology companies to claim that new types of genetic engineering, such as gene editing and synthetic biology, are not actually genetic engineering," said Megan Westgate, executive director of The Non-GMO Project. "To bring clarity in the face of this misleading trend, the Non-GMO Project has explicitly included these technologies in our Standard and cannot be used in a Non-GMO Project Verified product."

On the organic side, the National Organic Standards Board has proposed redefining genetic engineering in the National Organic Program to include GMOs 2.0 technologies, but the new definition hasn't yet been formally adopted.

No Regulation

There is virtually no regulation of GMOs 2.0 techniques in the U.S. The U.S. Department of Agriculture doesn't consider gene-edited crops such as Cibus's canola and Pioneer's waxy corn as falling under the agency's regulations for genetically engineered crops.

But Orf said the U.S. Department of Agriculture is deciding how GMOs 2.0 crops should be regulated. "They're reviewing their process to see if these crops should be regulated on a case-by-case basis or in a general way. These are different technologies doing things in a different way than transgenics."

Synthetic biology manufacturers are claiming their products such as vanillin are the same as the natural compounds and consider them to be "generally recognized as safe" or GRAS.

"Some companies are going to the Food and Drug Administration and saying 'we would like this to be GRAS' and the FDA is doing that," Thomas said.

Can GMOs 2.0 products be tested to detect their presence as current GMOs are?

"At this point, they are not developed, but they are developable," Thomas said.

"The companies will say their products can't be tested because they are the same as natural compounds. But if you talk with testing labs, they say they could develop a test. It is inevitable that tests will be developed because you have certifiers like the Non-GMO Project saying you can't use synthetic biology products."

See the rest here:
Next Generation of GMOs Escapes Regulation - EcoWatch

Posted in Genetic Engineering | Comments Off on Next Generation of GMOs Escapes Regulation – EcoWatch

Researchers find genetic link to female urinary incontinence – The Pharmaceutical Journal

Posted: at 10:14 pm

The first genetic variants to be associated with female urinary incontinence have been identified.

Researchers based in the UK and Poland carried out a genome-wide association study using data from 8,997 people and then confirmed their findings in a cohort of 4,069.

The team detected five genetic loci associated with stress and urgency incontinence, including two that were replicated in the second cohort.

One of these was located near the gene encoding endothelin 1, which is involved in muscle contraction in the bladder. This genetic variant was strongly associated with urgency urinary incontinence, a sudden and uncontrollable need to urinate that affects around 5% of women.

Another genetic variant linked to urinary incontinence in both cohorts was identified near a gene called MARCO, which is involved in immune function.

Although stress and urinary incontinence have been shown to be heritable, no genetic variants had previously been associated with the conditions.

The findings indicate that drugs targeting the endothelin pathway could be effective in urgency incontinence, such as those already used for treating pulmonary hypertension and Raynauds syndrome, the researchers say.

The identification of genetic variants could also lead to screening women for risk of developing the condition to help improve the advice given to them during pregnancy and inform the choice of delivery, the team suggests.

Clearly this will need further debate and an analysis, not just of the cost to healthcare systems, but also of the benefit to women who may be spared the distress of urinary incontinence, says researcher Rufus Cartwright at Imperial College London, who presented the findings[1] at the European Society of Human Genetics Annual Conference in Copenhagen.

Citation: The Pharmaceutical Journal, PJ May 2017 online, online | DOI: 10.1211/PJ.2017.20202869

Original post:
Researchers find genetic link to female urinary incontinence - The Pharmaceutical Journal

Posted in Human Genetics | Comments Off on Researchers find genetic link to female urinary incontinence – The Pharmaceutical Journal

Yale study finds cause of and cure for genetic skin disorder – Yale News

Posted: at 10:14 pm

About one in 200,000 people are affected by a severe group of skin disorders known as the ichthyoses (ik-thee-oh-sees), which feature dry, scaly, or thickened skin. Although treatment with topical medications can help, there is no cure. To better understand the cause of such skin disorders, a Yale-led research team studies the genes of individuals affected by the conditions.

Mutations underlying most types of ichthyosis have been identified, but roughly 15% of cases have unexplained origins, said associate professor of dermatology and senior author Dr. Keith Choate. To uncover potential new causes, the research team initially sequenced patients exomes (the protein-coding portions of the genome). They identified mutations in the gene KDSR that prevent the skin from producing ceramides fat molecules that seal the skin and protect it from water loss. Ceramides are naturally generated by the body, and are also a component of many commonly used moisturizers and cosmetics.

Interestingly, each of the study subjects has a KDSR mutation that might have been missed by standard analysis methods. Three of them have a silent substitution that usually would be considered harmless, but this particular mutation was demonstrated by the team to disrupt splicing the assembly of gene copies that are translated into proteins.

Additionally, while some subjects had observable mutations in both copies of the gene (one inherited from each parent), two subjects initially seemed to show only one mutation, said Dr. Lynn Boyden of the Yale Department of Genetics. This led us to look more closely, said Boyden, the lead author on the study.

The researchers noticed that both subjects shared a common benign variation in the KDSR gene. It appeared too frequently in the population to be disease-causing, but too rare to be a coincidental observation, and was a clue that these individuals likely also shared another KDSR mutation, one that contributed to disease but wasnt revealed by exome sequencing.

Sequencing of the entire genome of one of the subjects validated this hypothesis, exposing a large inversion that swapped the beginning of the KDSR gene with an unrelated sequence, and thereby disrupted the genes expression. Researchers often save money by sequencing only exomes, which are ~1% the size of genomes, but this is an example of the kinds of mutations that can be missed. This underscores the importance of comprehensively investigating unsolved genetic diseases, Boyden said.

The researchers also found that a commonly used acne medication, isotretinoin (Accutane), counteracts the effect of the mutations, allowing the skin to employ a different biological pathway to produce ceramides and to prevent the skin condition. In both patients whove utilized it, the medication has cured the disease, Choate said.

In addition to identifying effective treatment of a rare and disfiguring condition with an existing medication, the study results also highlight the central role of ceramides in skin health, and their value as common ingredients in many moisturizers and other cosmetic products, said the researchers.

Read the full paper, Mutations in KDSR cause recessive progressive symmetric erythrokeratoderma, in the American Journal of Human Genetics.

See the article here:
Yale study finds cause of and cure for genetic skin disorder - Yale News

Posted in Human Genetics | Comments Off on Yale study finds cause of and cure for genetic skin disorder – Yale News

How a Galpagos Bird Lost the Ability to Fly – New York Times

Posted: at 10:14 pm


New York Times
How a Galpagos Bird Lost the Ability to Fly
New York Times
Alejandro Burga, who analyzed the DNA of these and other cormorants with his colleagues, is a researcher in the lab of Leonid Kruglyak, the chairman of human genetics at U.C.L.A.'s medical school. He said he and Dr. Kruglyak were discussing how they ...
How the Galapagos cormorant lost its ability to flyUCLA Newsroom
Galapagos bird's evolution could aid study of bone diseaseTimes LIVE

all 6 news articles »

See the rest here:
How a Galpagos Bird Lost the Ability to Fly - New York Times

Posted in Human Genetics | Comments Off on How a Galpagos Bird Lost the Ability to Fly – New York Times

Man charged after DNA shows he fathered young relative’s child: Prosecutors – Chicago Tribune

Posted: at 10:14 pm

A 42-year-old man was ordered held on $750,000 bail Thursday after DNA testing showed he was the father of a young relative's child, officials said.

Frank Acevedo, of the West Lawn neighborhood, began touching the girl sexually not long after she turned 8, prosecutors said at a bond hearing Thursday.

As the girl grew older, the sexual assaults escalated, prosecutors said. The girl became pregnant at 15, giving birth in 2013. Months after giving birth she told another relative that Acevedo was the father, prosecutors said.

A search warrant was issued against him and required Acevedo to submit to a DNA swab in August 2016. The victim and her childalso were tested. Lab results dated in April came back with a 99.999 percent possibility of Acevedo being the father, prosecutors said.

Acevedo was arrested May 30, and charged with predatory criminal sexual assault and aggravated criminal criminal sexual assault. In his hearing Thursday, he wasordered held in lieu of $750,000 bail.

Read more from the original source:
Man charged after DNA shows he fathered young relative's child: Prosecutors - Chicago Tribune

Posted in DNA | Comments Off on Man charged after DNA shows he fathered young relative’s child: Prosecutors – Chicago Tribune

Microsoft Plans to Have a DNA-Based Computer by 2020 – Big Think

Posted: at 10:14 pm

Moores Law will run out soon. This is the idea that computer processing power doubles every 18 months. Some scientists say they can even see our progress beginning to slow. The microchip can only get so small. At a certain point, the silicon will be too small and thin for the heat itll endure and itll fry itself. Thats troubling. A lack of progress on this front could bring the swift velocity at which technology is progressing to a screeching halt.

So what will replace the microchip? How about DNA? Researchers have already saved a movie, a computer virus, an Amazon gift card, and more, on the building blocks of life. Currently, China has the worlds fastest supercomputer, known as the 93 petaflop Sunway TaihuLight. It can make 93,000 trillion calculations per second. The TaihuLight has 64 kilobytes of memory (64,000 bytes). Meanwhile, the human brain, arguably the most advanced computer ever, is estimated at one terabyte (1 trillion bytes) of memory.

The TaihuLight contains 41,000 chips, each with 260 processor cores, for a total of 10.65 million cores. The design isnt practical for mass market use. What about DNA, how does it measure up? In 2012, researchers at Harvards Wyss Institute stuck 700 terabytes of data into one single gram (0.03 oz.) of DNA.

A Chinese supercomputer. Wikipedia Commons.

Scientists estimate that DNA could hold 455 exabytes of data in all. An exabyte equals a quintillion bytes or 1 billion gigabytes. Since DNA is so densely packed, you could fit all of the worlds information on four grams (0.14 oz.) of DNA, a mere teaspoon full.

DNA allows nature to jam-pack a lot of information into a tiny space. Its fortunate that the nucleotide bases that make up DNA can easily be converted into binary code. Here, A (adenine) and C (cytosine) represent 0, and G (guanine) and T (thymine) represent 1.

Just four nucleotides are mere atoms wide. So you get the sense of how much you can pack in at this scale. We should be able to get one zettabyte, or a trillion gigabytes of storage, out of DNA in all, a mind-boggling figure.

If fossils have proven anything its that, DNA is incredibly durable, lasting millennia. Kept at subzero temperatures, it could last millions of years. Say we wipe out the human race and an intelligent extraterrestrial race came along at some point in the future. They might be able to decipher all of the information left behind by our species, in a package theyd likely recognize.

If kept at subzero temperatures, data saved on DNA could last millions of years. Getty Images.

So how does DNA computing work? Researchers using advanced algorithms translate data from computer language into DNA. Then to read it, the computer sequences the DNA.

Last year, Swiss researchers found a way to preserve DNA in silicon, much like a fossil, in order to protect it. While scientists at the University of Manchester, led by Prof. Ross D. King, created self-replicating DNA computers which grow as they go, to allow for tons more processing power, while using far less electricity. Scientists can easily build redundancies into the system too, making it more stable.

Now, Microsoft Research has announced that it will usher in an operational DNA-based computer by 2020. The plan is, according to partner architect Doug Carmean, a proto-commercial system in three years storing some amount of data on DNA in one of our data centers, for at least a boutique application. So you may be storing your information in a DNA-based cloud in the beginning of the next decade.

The first model is expected to be the size of one of a 1970s Xerox machine. Carmean told MIT Technology Review, We hope to get it branded as Your Storage with DNA. At first, the system is expected to only store really important information, such as medical records or police body-cam videos. Microsoft set a record last July, when it saved 200 megabytes of data directly onto DNA, a record.

1970s Xerox Machine. Getty Images.

One problem the company will need to overcome is the speed at which the system processes data. In this last experiment, the rate of converting data into DNA was 400 bytes per second. To make it commercially viable, itll need to reach 100 bytes per second.

Another obstacle, its incredibly expensive. Microsofts experiment used 13,448,372 individual pieces of DNA, which on the open market would cost $800,000. But getting it isnt enough. Encoding just one megabyte of data costs another $12,500.

Thats to say nothing of retrieving information. Sequencing costs about the same as encoding. One thing is, the price has dropped dramatically in recent years, and is likely to continue. But its still not enough to make the process practical. Microsoft hasnt announced any progress on the price front, but it may have something up its sleeve.

Though DNA-based computers are on the horizon, experts agree that the ultimate development would be quantum computing. This system would operate by holding quantum particles in superposition, or in two states at once, allowing for them to represent both 0 and 1 simultaneously. This would increase the calculation speed of certain operations exponentially.

The drawback is one cannot save anything on a quantum computer, due to whats known as the no cloning theorem. A DNA-quantum hybrid may be the answer.

To learn more about DNA-based computers, click here:

Read more:
Microsoft Plans to Have a DNA-Based Computer by 2020 - Big Think

Posted in DNA | Comments Off on Microsoft Plans to Have a DNA-Based Computer by 2020 – Big Think

Queens jogger’s dad lauds LAPD for using controversial DNA test – New York Daily News

Posted: at 10:14 pm


New York Daily News
Queens jogger's dad lauds LAPD for using controversial DNA test
New York Daily News
The father of slain Queens jogger Karina Vetrano is praising Los Angeles cops for using a controversial familial DNA analysis to arrest a man for the rape and murder of two young women. It's excellent news, Phil Vetrano told the Daily News Wednesday, ...
DNA Leads to Arrest Six Years After 2 Women Were Raped, Killed and Dumped on FreewaysInside Edition
How a rare DNA match cracked open a cold case of two young women dumped on LA freewaysLos Angeles Times
Police: Family Member's DNA Led To Man Suspected In KillingsCBS Los Angeles
New York's PIX11 / WPIX-TV -FOX 11 Los Angeles -Oxygen (blog) -Los Angeles Times
all 68 news articles »

Link:
Queens jogger's dad lauds LAPD for using controversial DNA test - New York Daily News

Posted in DNA | Comments Off on Queens jogger’s dad lauds LAPD for using controversial DNA test – New York Daily News

Scientists try to unwrap the secrets of Egyptian mummy DNA – Popular Science

Posted: at 10:14 pm

The Ancient Egyptians were famously fantastic at preserving their dead. But while their mummification methods helped protect soft tissues like skin from the ravages of time, the dry, hot climes that kept the deceased so pristine didn't do their genetic material any favors. Heat might help desiccate a corpse before rot sets in, but it also speeds up the degradation of DNA. So while scientists have been able to stare into the faces of countless Ancient Egyptians, they've had a lot of trouble deciphering any of the secrets of their genetic legacyuntil now.

Researchers publishing in Nature Communications believe they've conducted the first comprehensive genetic study on Egyptian mummies to avoid contamination. Their results suggest that modern-day Egyptians don't have much in common, genetically, with those entombed in their homeland.

Archeologists looked at 151 mummified remains from all walks of life, from lavish priestly burials to simple interments, all found at the Abusir el-Maleq archaeological site some 70 miles south of Cairo. In particular, the researchers zeroed in on mitochondrial DNA of these mummies. The DNA we usually talk about lives in the nucleus of each of our cells, and it comes from each of our parents. Mitochondrial DNA lives in the mitochondria, often called the powerhouse of the cell, and we only get it from our mothers. While it can't tell your entire genetic story, mitochondrial DNA is great for showing genetic changes over timehow different related lineages moved and met around the globe throughout the ages. In this case, they were able to get a clear read on mitochondrial DNA from 90 mummies, while only 3 mummies yielded reliable nuclear DNA sequences.

According to their findings, Egyptian demographics didn't change very much during the time range in which the various mummies livedbetween 1400 BC and 400 AD.

"There was no detectable change for those 1,800 years of Egyptian history," lead study author Johannes Krause of the Max Planck Institute for the Science of Human History in Germany told Reuters. "The big change happened between then and now."

Back then, it seems that the mummified Egyptians were most closely related to folks from the Levant, a region of the Eastern Mediterranean including modern-day Turkey, Israel, and Palestine. Today, Egyptians have more sub-Saharan African DNAsome eight percent more of their ancestry comes from this region.

The homogeny throughout the mummies studied is a bit surprising, as Egypt served as quite a cultural crossroads during this time. The results suggest that foreign invaders and bustling trade routes did little to rock the genetic continuity of Ancient Egyptiansat least in Abusir el-Meleq. Other researchersand the study authors themselvespoint out that the results can't be applied wholesale to the entire Ancient Egyptian culture. It's possible that more genetic mixing, including the addition of more sub-Saharan African genes, might have occurred on other shores of the Nile. If sub-Saharan genes did flood in starting just 1,500 years ago, it's likely that the growing slave trade in the area had something to do with it. Hopefully, future studies will help confirm the findings on these fragile remnants of DNAand uncover more secrets wrapped up on other mummies across the region.

This is the first glimpse of the genetic history of Egypt, Krause told Nature. But its really just the start.

Read more:
Scientists try to unwrap the secrets of Egyptian mummy DNA - Popular Science

Posted in DNA | Comments Off on Scientists try to unwrap the secrets of Egyptian mummy DNA – Popular Science

Obama Foundation Names Director For Presidential Center In Jackson Park – DNAinfo

Posted: at 10:14 pm

Louise Bernard has been named the first museum director for the Obama Presidential Center. View Full Caption

Obama Foundation, LinkedIn

HYDE PARK The Obama Foundation has picked Louise Bernard, the former director of exhibitions at the New York Public Library, to be the Obama Presidential Centers first museum director.

Bernard will be in charge of developing the museum into a place that tells the story of Barack Obamas life and presidency and also inspires civic engagement.

RELATED: OBAMA IS GOING DIGITAL FOR HIS PRESIDENTIAL CENTER

David Simas, CEO of the Obama Foundation, said the museum will need to inspire people to take on the worlds biggest challenges.

We are excited for Louise to join our team and help us develop a museum that is active and engaging, Simas said in an announcement Wednesday. Louises impeccable credentials and passion for her work will make her a valuable member of the Obama Foundation team.

Bernard will join some former colleagues on the project. She previously worked at Ralph Appelbaum Associates on the firms exhibition designs for the Smithsonians National Museum of African-American History and Culture. Appelbaum has been tapped by the Obama Foundation to also design the exhibitions for the presidential center in Jackson Park.

Im honored to work alongside such a talented team at the Obama Foundationand to have the opportunity to help guide and shape a museum that is a truly innovative social and cultural institution, Bernard said.

I look forward in bringing president and Mrs. Obamas remarkable story to the broadest possible audienceand to highlighting the crucial role of civic engagement in a way that is meaningful and inspiring to local South Side residentsand to people across the country and around the world, she said

Bernard is also a scholarly adviser to the International African American Museum in Charleston, S.C.

Read the rest here:
Obama Foundation Names Director For Presidential Center In Jackson Park - DNAinfo

Posted in DNA | Comments Off on Obama Foundation Names Director For Presidential Center In Jackson Park – DNAinfo

Bryan Habana: Rugby star’s surprise DNA discovery – CNN

Posted: at 10:14 pm

"Now I sort of understand why I might need to go to the toilet a bit more or why I'm a little bit more gassier than a normal person when I drink milk," he says.

"It hasn't meant I've stopped dairy, but I've changed the way I consume it."

Habana, the Springboks' all-time leading try scorer, was also surprised to find he has greater potential for increasing the endurance side of his training than past experience indicated.

"I was like, anything more than 100 meters is not my game training program. Maybe I could've responded better in terms of mentally pushing myself a bit harder. My body would've benefited a little bit more from that."

Along with power/endurance response -- which indicates what type of training intensity suits you best -- the DNAFit fitness test also provides guidelines for V02 max aerobic potential, post-exercise recovery, recovery nutrition and injury risk.

Habana teamed up with the company last year, and aims to build a DNA database of 1,000 professional rugby players by 2019.

However, he believes the test results can be just as beneficial for non-athletes as those at the elite level.

"It was very exciting to be part of a pioneering process where we're collecting as much data as possible, to be able to lay bases, to be able to find out more about the science," Habana says.

"Hopefully it'll have a big impact in making a difference in the sport, whether it be 1% for those at the elite level or 50-60% for those who are starting out in their careers and wanting to get to know their bodies better.

"What we'd like is for people to not only compare themselves to the likes of myself and hopefully a lot of other leading players in world rugby, but also to the normal person in the streets."

Like the other tests, it requires a simple saliva swab, which you send back to the lab. Then you receive a detailed report breaking down the results and making recommendations.

Kits cost from 99-249 ($120-$310).

This is what makes your body unique 01:26

DNAFit says its Peak Performance Algorithm is based on "validated genetic variant scoring methods."

"There are genome-wide association studies," the company's special projects manager Sebastian Corpe told CNN.

"They look at elite performers in particular sports -- for example elite power athletes, elite sprinters -- and they look for gene variations that appear in them more than the average population.

"Everything about who we are is the result of an interaction between how we were born and the things that we do. Genetics just shines a light on the static part of that equation, your DNA, so you can tailor your nutrition and training strategies to what will work for you."

Corpe says DNAFit has a rugby training plan specific to players' positions on the field -- front-five forwards, back-row forwards, inside backs and outside backs.

However, the company started out testing athletes such as sprinter Craig Pickering, and employs his fellow British Olympian Tom Lancashire among its consultants.

"We want to roll out those sorts of improvements into as many sports as possible to drive research not just in sports science but also in exercise genomics," he says.

Bryan Habana: The excitement of sevens 01:35

Now aged 33, he admits he is reaching the twilight of his career -- though he has prolonged it for at least another season after signing a contract extension with French club Toulon, where he has played since 2013.

He hopes the knowledge he has gained from DNA testing will help him manage his body, in an era where players are getting bigger, faster and stronger.

"Now I might be a little bit smarter in terms of how I train, in terms of my recovery process," Habana says. "I'm not going to change my whole training regime. Adding those elements that could help me train better and smarter could definitely help me over the next year or so of rugby that I have left.

"Getting that knowledge is so more useful now in terms of how I manage my career going forward and making sure that I train smarter to be able to stay at that highest level for as long as possible."

Habana, who is friends with DNAFit's founder, South African entrepreneur Avi Lasarow, says he hopes the company's approach can help take rugby to another level.

"Rugby has given me a huge amount over my career. In a small way, this is me helping to give something back, making a difference and pioneering a way where the next generation can be better, and the next generation after them can keep continually improving," he says.

"Playing a 1-2% part in making the sport grow to levels that it's never seen, I'd really love to do that. It's exciting, it's truly unique and I can't wait for it to start happening."

CNN's World Rugby show co-host Christina Macfarlane had her DNA tested, and compared her results with Habana's.

Both have the genetic ability to quickly recover between training sessions, meaning they can potentially do hard workouts within 24 hours of the previous one.

They have a low/normal risk of soft-tissue injury -- based on genetic markers for resilience of ligaments, tendons and joints.

However, Macfarlane had a greater response to power training -- a 60/40 split -- meaning she gets more benefit from heavier weights and high intensity levels than volume-based endurance exercise, though both should be included in any program.

On the diet side, Macfarlane has a medium-high sensitivity to carbohydrates, meaning she is more efficient at absorbing calories from such food sources. If weight management was a problem, this would be a key area to address. Her fat sensitivity is low, so this may be a better source of calories.

Her antioxidant and omega-3 requirements are normal, but she needs to increase her vitamin D and calcium intake for bone health.

She is a fast metabolizer of alcohol, meaning it leaves the blood quicker, and can get an increased performance boost from a small caffeine intake prior to training -- but has a gene which means elevated consumption can deplete bone mineral density.

See the article here:
Bryan Habana: Rugby star's surprise DNA discovery - CNN

Posted in DNA | Comments Off on Bryan Habana: Rugby star’s surprise DNA discovery – CNN

Page 1,780«..1020..1,7791,7801,7811,782..1,7901,800..»