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Category Archives: Transhuman News

Intrexon Integrates Leading Adenoviral Gene Delivery Technology with Completion of GenVec Acquisition – PR Newswire (press release)

Posted: June 16, 2017 at 2:44 pm

Additionally Intrexon's RheoSwitch Therapeutic Systemplatform combined with GenVec's AdV-based technology is projected to accelerate its ability to develop cutting-edge gene therapies that regulatein vivoexpression of one or several therapeutic effectors. GenVec's selection of vector origins and serotypes as well as know-how in specifying cellular and tissue targets is expected to expedite the design and production of vectors that complement Intrexon's multigene programming and keen focus on safety with limited off-target effect.

"GenVec's AdenoVerse platform is highly adaptable and can be customized to develop applications for regenerative and cell therapeutics as well as gene and antigen delivery strategies," commented Thomas D. Reed, Ph.D., Intrexon's Chief Science Officer. "The breadth of GenVec's natural and engineered adenovector serotypes displaying valuable targeted tissue specificity, when combined with our RheoSwitch Therapeutic System gene switch offer significant potential for cutting-edge in vivo multi-gene therapies."

Douglas E. Brough, Ph.D., GenVec's Chief Scientific Officer stated, "We look forward to combining our research and drug development team with Intrexon to advance groundbreaking in vivo therapeutics. Together we expect to develop a next-generation delivery platform capable of increasing payload capacity far beyond that of other viral methods for application to Intrexon's current and future health programs."

About Intrexon Corporation Intrexon Corporation (NYSE: XON) is Powering the Bioindustrial Revolution with Better DNA to create biologically-based products that improve the quality of life and the health of the planet. The Company's integrated technology suite provides its partners across diverse markets with industrial-scale design and development of complex biological systems delivering unprecedented control, quality, function, and performance of living cells. We call our synthetic biology approach Better DNA, and we invite you to discover more at http://www.dna.com or follow us on Twitter at @Intrexon, on Facebook, and LinkedIn.

Trademarks Intrexon, RheoSwitch Therapeutic System, Powering the Bioindustrial Revolution with Better DNA, and Better DNA are trademarks of Intrexon and/or its affiliates. Other names may be trademarks of their respective owners.

Safe Harbor Statement Some of the statements made in this press release are forward-looking statements. These forward-looking statements are based upon our current expectations and projections about future events and generally relate to our plans, objectives and expectations for the development of our business. Although management believes that the plans and objectives reflected in or suggested by these forward-looking statements are reasonable, all forward-looking statements involve risks and uncertainties and actual future results may be materially different from the plans, objectives and expectations expressed in this press release.

For more information regarding Intrexon Corporation, contact: Investor Contact:Christopher Basta Vice President, Investor Relations Tel: +1 (561) 410-7052 investors@intrexon.com

Corporate Contact:Marie Rossi, Ph.D. Director, Technical Communications Tel: +1 (301) 556-9850 publicrelations@intrexon.com

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/intrexon-integrates-leading-adenoviral-gene-delivery-technology-with-completion-of-genvec-acquisition-300475225.html

SOURCE Intrexon Corporation

http://www.dna.com

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Intrexon Integrates Leading Adenoviral Gene Delivery Technology with Completion of GenVec Acquisition - PR Newswire (press release)

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What If (Almost) Every Gene Affects (Almost) Everything? – The Atlantic

Posted: at 2:44 pm

In 1999, a group of scientists scoured the genomes of around 150 pairs of siblings in an attempt to find genes that are involved in autism. They came up empty. They reasoned that this was because the risk of autism is not governed by a small number of powerful genes, which their study would have uncovered. Instead, its likely affected by a large number of genes that each have a small effect. Perhaps, they wrote, there might be 15 such genes or more.

Two decades later, that figure seems absurdly and naively low. If you told a modern geneticist that a complex traitwhether a physical characteristic like height or weight, or the risk of a disease like cancer or schizophreniawas the work of just 15 genes, theyd probably laugh. Its now thought that such traits are the work of thousands of genetic variants, working in concert. The vast majority of them have only tiny effects, but together, they can dramatically shape our bodies and our health. Theyre weak individually, but powerful en masse.

But Evan Boyle, Yang Li, and Jonathan Pritchard from Stanford University think that this framework doesnt go far enough.

They note that researchers often assume that those thousands of weakly-acting genetic variants will all cluster together in relevant genes. For example, you might expect that height-associated variants will affect genes that control the growth of bones. Similarly, schizophrenia-associated variants might affect genes that are involved in the nervous system. Theres been this notion that for every gene thats involved in a trait, thered be a story connecting that gene to the trait, says Pritchard. And he thinks thats only partly true.

Yes, he says, there will be core genes that follow this pattern. They will affect traits in ways that make biological sense. But genes dont work in isolation. They influence each other in large networks, so that if a variant changes any one gene, it could change an entire gene network, says Boyle. He believes that these networks are so thoroughly interconnected that every gene is just a few degrees of separation away from every other. Which means that changes in basically any gene will ripple inwards to affect the core genes for a particular trait.

The Stanford trio call this the omnigenic model. In the simplest terms, theyre saying that most genes matter for most things.

More specifically, it means that all the genes that are switched on in a particular type of cellsay, a neuron or a heart muscle cellare probably involved in almost every complex trait that involves those cells. So, for example, nearly every gene thats switched on in neurons would play some role in defining a persons intelligence, or risk of dementia, or propensity to learn. Some of these roles may be starring parts. Others might be mere cameos. But few genes would be left out of the production altogether.

This might explain why the search for genetic variants behind complex traits has been so arduous. For example, a giant study called er GIANT looked at the genomes of 250,000 people and identified 700 variants that affect our height. As predicted, each has a tiny effect, raising a persons stature by just a millimeter. And collectively, they explain just 16 percent of the variation in heights that you see in people of European ancestry. Thats not very much, especially when scientists estimate that some 80 percent of all human height variation can be explained by genetic factors. Wheres that missing fraction?

Pritchards team re-analyzed the GIANT data and calculated that there are probably more than 100,000 variants that affect our height, and most of these shift it by just a seventh of a millimeter. Theyre so minuscule in their effects that its hard to tell them apart from statistical noise, which is why geneticists typically ignore them. And yet, Pritchards team noted that many of these weak signals cropped up consistently across different studies, which suggests that they are real results. And since these variants are spread evenly across the entire genome, they implicate a substantial fraction of all genes, Pritchard says.

The team found more evidence for their omnigenic model by analyzing other large genetic studies of rheumatoid arthritis, schizophrenia, and Crohns disease. Many of the variants identified by these studies seem relevant to the disease in question. For example, some of the schizophrenia variants affect genes involved in the nervous system. But mostly, the variants affect genes that dont make for compelling stories, and that do pretty generic things. According to the omnigenic model, theyre only contributing to the risk of disease in incidental ways, by rippling across to the more relevant core genes. Its the only model I can come up with that make all the data fit, Pritchard says.

Pritchards a very perceptive investigator, who looks beyond what most people do, says Aravinda Chakravarti, a geneticist at John Hopkins Medicine. Do I believe this all correct? No, but its very compelling. Its a serious hypothesis that weve got to prove or disprove.

If Pritchard is right, it has big implications for genetics as a field. Geneticists are running ever-bigger and more expensive searches to identify the variants behind all kinds of traits and diseases, in the specific hope that their results will tell them something biologically interesting. They could show us more about how our bodies develop, for example, or point to new approaches for treating disease. But if Pritchard is right, then most variants will not provide such leads because they exert their influence in incidental ways.

Put it this way: The Atlantic is produced by all of us who work here, but our lives are also affected by all the people we encounterfriends, roommates, partners, taxi drivers, passers-by etc. If you listed everyone who influences what happens at The Atlantic, even in small ways, all of those peripheral people would show up on the list. But almost none of them would tell you much about how we do journalism. They're important, but also not actually that relevant. Pritchard thinks the same is true for our genes. And if thats the case, he says, its not clear to me that increasing your study size is going to help very much.

The alternative, he says, is to map the networks of genes that operate within different cells. Once we know those, well be better placed to understand the results from the forthcoming mega-studies. It is a really hard problem, says Boyle. Historically, even understanding the role of one gene in one disease has been considered a major success. Now we have to somehow understand how combinations of seemingly hundreds or thousands of genes work together in very complicated ways. Its beyond our current ability.

There are, however, projects that are trying to do exactly that. Im very excited about trying to understand whether these network ideas are correct, says Pritchard. I think its telling us something profound about how our cells work.

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Trump yearbook censorship: Wall teacher is a registered Democrat – Asbury Park Press

Posted: at 2:43 pm

Grant Berardo, a Wall High School junior, saw his image digitally altered with a plain black T-shirt in his yearbook. Mike Davis

Wall Township High School junior Grant Berardo's T-shirt was digitally altered in the school's yearbook. He wore a Donald Trump campaign shirt for his portrait.(Photo: Courtesy of Joseph Berardo, Jr.)

WALL -The teacher at the center of a censorship scandal in the Wall High School yearbook is a registered Democrat, according to public records.

Susan Parsons, 62, was suspended from her position as a digital media teacher and yearbook adviser on Monday after two students reported their school pictures were altered in the yearbook to remove references to President Donald Trump.

According to the Monmouth County election board, Parsons is a registered Democrat. She voted in the November 2016 general election but public records do not indicate which candidate she voted for.

ICYMI: Wall High teacher suspended over alleged Trump yearbook censorship

MORE INFO: Wall teen's Trump shirt censored in yearbook

But the young Trump supporters believe they were slighted specifically.

Grant Berardo, a junior at the school, took his school pictures wearing a navy blue "Make America Great Again" shirt from the campaign. But in the yearbook, his photo had been digitally altered so it resembled a nondescript black T-shirt, which you can see in the video at the top of the story.

It was Photoshopped," Grant said in an interview on Friday. "I sent it to my mom and dad, just like You wont believe this. I was just overall disappointed.

"I like Trump, but its history too. Wearing that shirt memorializes the time," he said.

Wall High School(Photo: File photo)

According to CNN, Wyatt and Montana Dobrovich-Fago also alleged censorship. The Trump logo on Wyatt's sweater vest in his picture was seemingly cropped out. And a quote attributed to Trump was inexplicably left out of a section dedicated to Montana's role as freshman class president.

Traditionally, class presidents pick a quote to accompany their picture.

DISAFFECTED:Trump supporters at the Shore 'want their country back'

TRUMP BUDGET:A guide for the Shore

"I like thinking big. If you are going to be thinking anything, you might as well think big," Trump's quote read.

Though none of the students were able to vote in last year's election, they certainly aren't alone in their support of Trump.

Wall is a strongly Republicantown in a strongly Republican county. All five Township Committee members and Monmouth County freeholders are Republican, andthe town is represented by Republicans in the state Senate, Assembly and House of Representatives.

ELSEWHERE: Bleeding liberal blue in red Jackson

Last year, the number of Trump voters nearly doubledthe 5,000 who voted for Democratic candidate Hillary Clinton. About 61 percent, just over 9,400 voters,in Wall supported Trump.

In Parsons'voting district, 434 people voted for Trump. Just 172 voted for Clinton.

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According to her LinkedIn page, Parsons has worked in the district for 15 years.

On her yearbook class'website within the district homepage, Parsonsincludes "photo editing" as one of the "real world skills" that students learn during yearbook production.

An office manager at the Wall Township Education Association, the district's teacher union, said there was no one there who could comment. Union officials did not immediately respond to requests for comment.

Parsons has not returned multiple calls to her home seeking comment. Nobody answered the door at her listed address in Wall.

In an interview with the New York Post, Parsons said we have never made any action against any political party.

But when asked if she knew who altered the photos, Parsons simply said, Im going to hang up.

Mike Davis: 732-643-4223; mdavis@gannettnj.com

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Wikileaks Documentary Makers Accuse Assange of Censorship – Newsweek

Posted: at 2:43 pm

We are the producers of Risk , a documentary film about Julian Assange and WikiLeaks.

We unequivocally defend WikiLeaks journalistic right to publish true and newsworthy information.

The Trump administrations threats against WikiLeaks and attacks on press freedom are chilling. As Margaret Sullivan recently argued in the Washington Post, prosecuting WikiLeaks under the Espionage Act would set a dangerous precedent for all journalists.

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We were disturbed, however, to learn that Julian Assange and WikiLeaks sent cease and desist letters to our distributors demanding they stop the release of Risk: We therefore demand that you immediately cease the use and distribution of all images of the Named Participants and that you desist from this or any other infringement of the rights of the Named Participants in the future.

In WikiLeaks efforts to prevent the distribution of Risk , they are using the very tactics often used against them legal threats, false security claims, underhanded personal attacks, misdirection and with the same intentions: to suppress information and silence speech.

Filmmaker Laura Poitras speaks as former National Security Agency (NSA) contractor turned whistleblower Edward Snowden is seen on a video conference screen during an award ceremony for the Carl von Ossietzky journalism prize on December 14, 2014 in Berlin, Germany. Adam Berry/Getty

Since 2016, Assange and his lawyers have repeatedly demanded that we remove scenes from the film in which Assange speaks about the two women who made sexual assault allegations against him in 2010 and Swedens investigation which has since been discontinued.

In response to our refusal to remove these scenes, Assange and his lawyers are now claiming that Risk threatens the safety of the staff who consented to being filmed, and furthermore, that we are being sexist by including Assanges own comments about women in the film.

These arguments are not only false, they are a deliberate effort at misdirection.

Risk was filmed over the course of many years, beginning in 2011. Assange and WikiLeaks freely consented to participating in the film, knowing we were making an independent documentary. Neither WikiLeaks nor Assange have any editorial control of Risk. There were individuals who requested from the beginning not to appear in the film, and those requests were respected.

Wikileaks and their lawyers were shown the film before each public screening, most recently inside the Ecuadorian embassy in London on April 1, 2017. Each time, we invited their responses.

WikiLeaks comments have consistently been about image management, including: demands to remove scenes from the film where Assange discusses sexual assault allegations against him; requests to remove images of alcohol bottles in the embassy because Ecuador is a Catholic country and it looks bad; requests to include mentions of WikiLeaks in the 2016 U.S. presidential debates; and, requests to add more scenes with attorney Amal Clooney because she makes WikiLeaks look good.

It is only after we declined to make the changes they tried to impose that WikiLeaks raised objections to Risk . Their attempts to censor the content of the film are an effort to prevent reporting on Assanges own words. They also constitute a saddening break with WikiLeaks own ideals.

Last month, WikiLeaks lawyers published an op-ed saying they object to our editing in the United States. However, Assange has known since 2015 that we were editing in the U.S. In 2016, he signed an agreement to license WikiLeaks own footage to us and raised no objection to mailing a hard drive with footage directly to our editing room in New York City.

WikiLeaks has also repeatedly publicized their participation in Risk , most recently re-tweeting a link to the films trailer on April 10, 2017 (a tweet that has since been deleted), without raising any concerns.

In their cease and desist letter, lawyers for WikiLeaks and Assange state: The unauthorized release of the Film has caused our clients to suffer ongoing irreparable harm, and exponentially increasing damages every time a new viewer sees the Film.

All the participants in Risk agreed for years to be in the film. We have no obligation to seek WikiLeaks or Assanges authorization to release the film. In fact, our rights under the First Amendment are protected precisely because we are engaging in independent journalism. Assange himself has criticized the media for seeking permission from public figures before releasing stories.

Like WikiLeaks, our journalism has been the target of U.S. government investigation, secret grand jury, and threats by elected officials. We fully understand and empathize with the dangers WikiLeaks is facing, and we stand in solidarity with all journalists and publishers around the world currently under attack.

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Who Is Ron Paul?

Posted: at 2:43 pm

Ron Paul is Americas leading voice for liberty, prosperity and peace. As a former member of the U.S. House of Representatives and three-time presidential candidate, Ron Paul tirelessly works for limited, constitutional government, low taxes, free markets, and a return to sound monetary policies. Ron Paul never voted for legislation unless the proposed measure was expressly authorized by the Constitution.

Ron Paul was born and raised in Pittsburgh, Pennsylvania. He graduated from Gettysburg College and the Duke University School of Medicine, before proudly serving as a flight surgeon in the U.S. Air Force during the 1960s. He and his wife Carol moved to Texas in 1968, where he began his medical practice in Brazoria County. As a specialist in obstetrics/gynecology, Dr. Paul has delivered more than 4,000 babies. He and Carol, who reside in Lake Jackson, Texas, are the proud parents of five children and have 17 grandchildren.

While serving in Congress during the late 1970s and early 1980s, Dr. Pauls limited-government ideals were not popular in Washington. In 1976, he was one of only four Republican congressmen to endorse Ronald Reagan for president. During that time, Congressman Paul served on the House Banking committee, where he was a strong advocate for sound monetary policy and an outspoken critic of the Federal Reserves inflationary measures. He was an unwavering advocate of pro-life and pro-family values. Dr. Paul consistently voted to lower or abolish federal taxes, spending and regulation, and used his House seat to actively promote the return of government to its proper constitutional levels. In 1984, he returned to his medical practice.

Ron Paul went back to Congress in 1997 to represent the 14th congressional district of Texas. He served on the House Committee on Financial Services and the House Committee on Foreign Affairs, and eventually became Chairman of the Subcommittee on Domestic Monetary Policy and Technology. After retiring from Congress in early 2013, Ron Paul continued to advocate a dramatic reduction in the size of the federal government and a return to constitutional principles.

On the Issues: Audit the Federal Reserve, Our Money, Taxes, National Defense, Border Security, Civil Liberties, Health Care, Abortion, Education, War on Drugs, Global Warming

Learn more about this grassroots-run website.

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Comics and Liberty: How Basic Libertarian Principles Parallel Comic … – The Libertarian Republic

Posted: at 2:42 pm

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By Chris Massari

There is a largely missed connection between the comic medium, particularly the superhero genre and stories from the two big publishers Marvel and DC, and the philosophies associated with libertarianism. Everything from the non-aggression principle (NAP), individualism, civil liberty, voluntary action and in some cases/stories to individuals versus the State. In fact, one could say that the parallels between the two are almost too spot on.

Anyone with a basic understanding of pop culture can easily identify the very nature of volunteer action and connect that with superheroes. Id be surprised if youve never heard the phrase With great power, comes great responsibility and not instantly know what its from and what that quote is presenting. You dont even have to just use Spider-Man to present the idea of voluntary action. Use Batman, use Superman, use Wonder Woman, The Flash or Daredevil, and really any of the majority of comic heroes can easily be substituted in and out as examples for voluntary philosophies. Voluntary action is in the very nature of the mediums stories and individuals using their unique abilities towards a public good, doing a service voluntary of the state through individual actions.

To take it one step further withcomics and libertarian ideals, one could explore the vast history of Superman following a non-interventionist foreign policy when it comes to handling situations outside of the United States, not including Frank Millers The Dark Knight Returns. This one example doesnt even include the deeper and more complex philosophical parallels in major or even minor story lines. This is just one character that consistently follows a particular ideological stance that falls right in line with the libertarian model.

Now, if you were trying to best convey libertarian philosophies in a comic, I think the perfect introductory look would be Marvels Civil War arc in 2006 by Mark Millar. This story was even repackaged recently to fit Marvels cinematic universe in Captain America: Civil War. While the film is much less complex than the comic version, the core principles remain the same. Individual versus State, where comic heroes are being forced by the government into mandatory registration of their abilities and identities. If they dont register, they cannot legally be heroes or engage in hero related activities. It kind of reminds me of that meme going around on the internet where someone feeds the homeless, only to be arrested for feeding the homeless, only to be forced into doing mandatory community service. Here, its acts of heroism being condemned by the State.

In both the comic and film, the ideological battle of Individual versus State is represented by Captain America, the individualist and Iron Man, the State advocate. Anyone familiar with the film will recognize this dialogue:

Tony Stark: Oh, thats Charles Spencer by the way. Hes a great kid. Computer engineering degree. 3.6 GPA. Had a floor-level gig at Intel planned for the fall. But first, he wanted to put a few miles on his soul, before he parked it behind a desk. See the world, maybe be of service. Charlie didnt want to go to Vegas or Fort Lauderdale, which is what I would do. He didnt go to Paris or Amsterdam. Sounds fun. He decided to spend his summer, building sustainable housing for the poor. Guess where Sokovia. He wanted to make a difference, I suppose. I mean, we wont know because we dropped a building on him while we were kicking ass. Theres no decision-making process here. We need to be put in check. Whatever form that takes, Im game. If we cant accept limitations, were boundaryless, were no better than the bad guys.

Steve Rogers: Tony, someone dies on your watch, you dont give up.

Tony: Who said were giving up?

Steve: We are if were not taking responsibility for our actions. This document just shifts the blame.

Col. James Rhodes: Sorry. Steve, that, that is dangerously arrogant. This is the United Nations were talking about. Its not the World Security Council, its not SHIELD, its not HYDRA.

Steve: No, but its run by people with agendas and agendas change.

Tony: Thats good. Thats why Im here. When I realized what my weapons were capable of in the wrong hands, I shut it down and stop manufacturing them.

Steve: Tony. You chose to do that. If we sign these, we surrender our right to choose. What if this panel sends us somewhere we dont think we should go? What if its somewhere we need to go, and they dont let us? We may not be perfect, but the safest hands are still our own.

Tony: If we dont do this now, its gonna be done to us later. Thats a fact. That wont be pretty.

This conversation highlights the crux of the ideological argument presented in the story and can be perfectly applied to the libertarian platform as a palatable and understandable representation of what the party values to a mainstream audience.

I say this because its no secret that entertainment generally leans Left and recently, leaning to a Regressive rather than Progressive atmosphere. People gravitate towards entertaining things and if a particular ideology can be presented in a fun, easy to digest fashion, its not difficult to push your narrative whatever it is. Now, I need to add this isnt a Down with the Liberal Media statement but, more an observation of presenting ideas to a wide stream audience, something I, unfortunately, feel the Libertarian party hasnt quite gotten right just yet.

What I do find interesting is that when certain ideas, like the Libertarian philosophies presented in Civil War, are shown in entertainment, people agree with them and can even become passionate about it. Do a little google research and you can see how adamantly people argued over who was right in the original Civil War comic run. Fighting vehemently over who was right, Captain America or Iron Man. However, when applied to real life actions and politics, the Libertarian Party can be viewed as a three-headed monster or laughing stock depending on who you ask. There are obvious reasons for that from lack of education in the mainstream, the various factions within the Party, the two-party system and of course, the saying that getting Libertarians in order is like leading cats to water.

That said, I think if the Libertarian Party can learn to take these easy and palatable parallels in comics or other entertainment mediums, it can help to better present these ideas, principles, values, and philosophies in a manner that people like, enjoy and might even take part in down the road. I believe exploring the vast amounts of stories in comics that directly present Libertarian values so often and easy to understand, could be a great way to present the values of Liberty and individualism to a wider audience.

So, read a comic and support Liberty and the individual or something like that.

Captain AmericaCaptain America Winter SoldierCaptain America: Civil Warcomic bookComic Book Moviescomic bookscomicsdc comicsMarvelmarvel comicsMarvel Studiosopinionphilosophypolitical opinionpolitical philosophy

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Peter Espeut | Libertarianism or the common good? – Jamaica Gleaner

Posted: at 2:42 pm

The LGBT lobby has its allies in the pro-abortion, pro-prostitution, pro-euthanasia, pro-drug-use advocacy groups, and its members have joined together in common cause to assert their 'rights', and they call upon the government to decriminalise, legalise, and normalise their favourite pastimes.

Philosophically, they are all in the same camp: they are libertarians, promoting the idea that consenting individuals should be free to do whatever they choose as long as it does no harm and does not infringe upon the 'rights' of others, but these 'others' and their 'rights', and any possible harm involved, are usually defined in a very narrow and often perverse way.

For abortion to be defensible, the existence of a human being in the womb has to be denied (despite scientific evidence to the contrary), otherwise their right to life would have to be defended. For prostitution to be defensible, sexual intercourse has to be defined as a commodity to be repeatedly bought and sold, implying no emotional involvement and causing no emotional harm. For euthanasia to be defensible, human life itself has to be devalued, especially the lives of the disabled and the terminally ill.

Libertarianism glorifies the freedom of the individual to choose what is good (and pleasurable) and convenient for himself or herself without any regard to the common good.

It suits the libertarian lobbyists to posit that libertarianism and the philosophy that underpins it are the most logical and sensible way to organise modern society, and that organised religion, whose principles, based on scriptures dating back several millennia (which are in profound conflict with libertarianism), are outdated and are holding back progress. Fundamentalist Christians play into their hands by thumping their Bibles even harder! Asserting the authority of a text Libertarians reject can advance the argument no further, and I wish fundamentalists would stop it.

It does no disrespect to the Bible or the Holy Qu'ran to use well-authenticated, wholly secular philosophical arguments to refute and discredit libertarian philosophy as being pathologically individualistic and selfish, and operating contrary to the common good, which is the end towards which society is to be organised and governed.

To speak about ethics is not automatically to speak of religion. Secular Greek philosopher Aristotle wrote his book, titled Ethics, around 350 years before Christ was born. Aristotle argued that political constitutions were right if they were in the common interest and wrong if they were in the interest of the rulers.

These ancient ideas were developed over the centuries by other secular political philosophers. John Locke declared that "the peace, safety, and public good of the people" are the ends of political society. David Hume contended that social conventions are adopted and given moral support by virtue of the fact that they serve the public or common interest. Jean-Jacques Rousseau understood the common good to be the object of a society's general will and the highest end pursued by government.

The fundamental building block of the society is the family. This is not a religious principle, but a socio-political one. Weak families lead to improperly socialised children, lowering their potential to benefit from education and increasing their potential for dysfunctional behaviour and the development of an unbalanced personality. Anything that strengthens the family strengthens society as a whole; and anything that undermines the family, undermines the integrity of society.

The common good is the good of all people and of the whole person. No group within society is to be excluded from its benefits, and integral human development includes the intellectual, physical, artistic and emotional facets of the human person. The task of the State is to work for the development of the whole person, and of all the people, and in doing so, the virtues of temperance, honesty, fairness, openness, and justice are brought into play.

The fundamental question we need to answer is, which of these two moral philosophies should we employ to govern Jamaican society? Libertarianism, which is directed towards satisfying the cravings of individuals or the philosophy of the common good?

If we choose libertarianism, how can we blame politicians for taking decisions that line their pockets? They would, after all, be taking decisions that are in their best interests rather than the common good.

The arguments being put forward by libertarians to legalise buggery, prostitution, and abortion should be rejected, not because they run against religious norms, but because they do not serve the common good.

- Peter Espeut is a sociologist and Roman Catholic deacon. Email feedback to columns@gleanerjm.com.

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Study: Daily Dose of THC Can Reverse Aging of Brain – Green Rush Daily

Posted: at 2:42 pm

Its fair to say that U.S. culture obsesses over youthfulness. But its certainly not the only one. Dreams of immortality and everlasting youth have been a part of the popular imagination for millennia, and the quest continues today. Yet while most anti-aging products out there target the signs of aging that affect your body, a new cannabis study suggests a daily dose of THC can actually reverse the aging of the brain.

Teams from the University of Bonn and the Hebrew University of Jerusalem, a leader in medical cannabis research, came together to study how daily micro-doses of THC effected the aging process of brain cells.

Their subjects were mice, not humans. But the results were remarkable. Of course, mice dont live nearly as long as we do and their brains are much simpler. But they do live long enough and are complex enough that researchers can observe the effects of aging.

When the brain ages, it slows down. Older people literally get slower. The nerve impulses and transmissions take longer to reach their destinations. As a result, as we age our brains begin to lose cognitive functions like memory, the ability to learn new things, and motor coordination.

But with a little help from a daily dose of THC, the psychoactive cannabinoid found in cannabis, researchers found that many of those functions can be temporarily and significantly restored.

In short, THC helped turn old brains into young brains again. Or in the words of Professor Andreas Zimmer, The treatment completely reversed the loss of performance in the old animals.

In the study, researchers used mice of different age groups. The mice performed memory, recognition, and navigation tasks.

The younger mice completed the tasks with no problems when they were sober, not under the influence of THC. Presumably, this is because their younger brains were sharper. However, when researchers began giving the young mice adaily dose of THC, they began to significantly struggle with the puzzles.

The story was the complete opposite with the older mice. They struggled with the challenges without THC. But a daily dose of THC soon began to dramatically increase their brain performance, up to the same level as the younger mice.

Specifically, the study said that in terms of memory and learning, the older mice were able to regress to the state of atwo-month-old mouse.

These findings, while still at the level of animal testing, show significant promise for aging humans.

Co-authors Zimmer and Svenja Schulze believe a THC daily dose could be an effective alternative for treating problems like dementia. They hope to begin trials on humans later this year.

One thing that remains to be seen is whether the psychoactive effects of cannabis will produce different results in humans than in mice. According to the researchers, THC did not appear to influence the mice in the same way as humans.

In other words, the daily dose of THC didnt make the mice get high. However, there could be other negative side-effects for human brains. The research is of course still in the very early phases.

Restrictions on the legal research of medical cannabis in the United States and the UK have slowed the teams progress. So its unlikely that doctors will be prescribed THC for older folks memory problems anytime soon.

Nevertheless, the findings are extremely promising. As researchers discovered, brain health is very closely linked to the endocannabinoid system. Comprised of the neural pathways and receptors specially designed for cannabinoids, that system is essential in preventing brain deterioration. Its what makes cannabis such an effective medicine for neurological diseases like Alzheimers and epilepsy.

Weve written elsewhere about how cannabis can help save the United States medicare and medicaid programs. Thats because medical cannabis is a safe and cheap alternative to costly prescription drugs.

But if cannabis can help reduce the number of seniors needing care, it can help reduce the countrys healthcare costs even further. One of the studys co-authors, Dr. Andras Bilkei-Gorzo, is very optimistic in this regard. She told the Guardian, If we can rejuvenate the brain so that everybody gets five to ten more years without needed extra care, then that is more than we could have imagined.

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Study: Daily Dose of THC Can Reverse Aging of Brain - Green Rush Daily

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New iOS Games and Apps of the Week: PS4 PlayLink and more – The iPad Guide

Posted: at 2:41 pm

Sony announced PlayLink for the PlayStation 4 at E3 this week. The new app allows users to play games on their console by using the touchscreen of their iOS device. Sony previewed a few upcoming PlayLink titles that will be availble at launch. Check out the descriptions and trailers below.

PlayLink will be available for free on both the App Store and Google Play on July 4th.

That's You! - An audacious comedy quiz which challenges you and up to five friends to get personal and find out what you really think about each other. Featuring over 1,000 varied questions, reveal your daring side by taking part in doodle challenges and snapping selfies.

Hidden Agenda - This narrative-driven adventure drops you into a detective thriller rife with chilling moral dilemmas that may determine life or death. Up to six of you can join in to make tough decisions about how the story unfolds, but not all of you will be working towards the same objective

Knowledge is Power - Answer a variety of trivia questions and outsmart up to five opponents, with power plays and challenges thrown in to keep you on your toes. This game is all about speed and accuracy in the face of some wickedly crafted distractions from your opponents are you up to the task?

Frantics - Arcade-style fun and manic mini-games are all the rage in Frantics, where you and up to three friends have to face off in a variety of challenges. Bluff, battle, negotiate and co-operate your way to victory, but beware mischievous host The Fox is also on hand to stir things up.

SingStar Celebration - Hit the high notes with upbeat tracks, massive hits and your favorite party classics. Whether its your birthday, Christmas, New Years Eve or even just a Saturday night SingStar Celebration is the perfect playlist to any party, with up to eight players able to join in the fun. Use your SingStar mic or combine your smartphone with the SingStar Mic App, and get ready for your big moment.

Players who pre-register for Pocket Knights 2 at http://www.pocketknights2.com will receive exclusive rewards. The sequel to the hit RPG is set to launch worldwide on the App Store after soft launching on Google Play. You can visit the mini site link posted above or Facebook for more details about the game.

Feral Interactive announced that Hitman: The Complete First Season is coming to macOS on June 20th. The Mac version will include all six international missions and three bonus missions from the Linux version of the game.

Here are this week's noteworthy App Store releases:

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New iOS Games and Apps of the Week: PS4 PlayLink and more - The iPad Guide

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Grab one of 2000 Post Human WAR beta keys and start playing right now! – PCGamesN

Posted: at 2:41 pm

Humanity has died out and all that's left on Earth are the mutated animals and household robots we left behind. This is how you're introduced to the world of Post Human W.A.R, a turn-based strategy game that pits sentient vacuum cleaners against tracksuit monkeys against each other in warfare.

There are, in fact, three different factions - or groups - to choose from in Post Human W.A.R. They're all battling to decide the fate of the world now that humans have been wiped out. The mutated animals are hoping to destroy everything - they're pretty angry about the state they've been left in - the robots are hoping to protect humanity's heritage, and finally the monkeys are hoping to pick back up where the humans left off, becoming the new dominant species.

Once you've picked which side you'll serve, you then enter battle with the others, which requires you to pick units and spread them across a honeycomb grid - positioning your fighters to be the most effective is crucial. While fighting, either in single-player or online against strangers, you'll also need to make use of the environment, as well as react to the enemy's bluffs - adding a psychological level to the game's tactics.

If you want to get involved in the beta of Post Human W.A.R right now, you can. Just enter via our widget below and unlock your key.

When you've grabbed your code redeem via Steam. Simply click the Add a Game button at the bottom left of the Steam client window, and Activate a Product on Steam. Follow the instructions, download the game, and get playing!

If you like our giveaways and want to be kept in the loop about them, head over and give thePCGamesN Facebook page a likeorfollow us on Twitter.

Post Human W.A.R giveaway

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Grab one of 2000 Post Human WAR beta keys and start playing right now! - PCGamesN

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