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Category Archives: Transhuman News
Elon Musk Details His Vision For A Self-Sustaining City On Mars – Forbes
Posted: June 17, 2017 at 1:47 pm
Mashable | Elon Musk Details His Vision For A Self-Sustaining City On Mars Forbes So why Mars, rather than the Moon, which is closer and might seem more accessible as humanity's first colony? Musk makes several arguments in favor of the Red Planet. "I think it is challenging to become multi-planetary on the moon because it is much ... Making Humans a Multi-Planetary Species - Mary Ann Liebert, Inc. publishers |
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State Research Centers To Receive State Funding – Yankton Daily Press
Posted: at 1:46 pm
PIERRE South Dakotas Research and Commercialization Council (RCC) has selected four research centers to receive funding through the Governors Research Center Program.
At its meeting last month, the RCC chose the following new centers for funding:
South Dakota Center for Biologics Research & Commercialization, led by Dr. Christopher-Hennings at South Dakota State University, will receive $3,817,603 over five years to conduct translational research in nutraceuticals, probiotics, vaccines and diagnostic collaboration with industry partners, who will license and commercialize the technologies developed by the center. The centers overarching goal is to become a nationally recognized center of excellence in biologics research.
Center for Fluorinated Functional Materials, led by Dr. Sun at the University of South Dakota, will receive $2,710,969 over five years to build a self-sustaining discovery-based research center to commercialize fluorinated functional materials in the sectors of materials and advanced manufacturing, energy and environment and human health and nutrition.
Center for Genetics & Behavioral Health, led by Dr. Forster at the University of South Dakota, in collaboration with the Avera Institute for Human Genetics, will receive $3,466,300 over five years to study genetic and environmental influences that interact with other biological, psychological and behavioral factors to impact post-traumatic stress disorder (PTSD). The center aims to place South Dakota at the forefront of personalized treatment of trauma-related illness to significantly reduce the substantial health, financial and personal burden of PTSD and associated disorders.
Composite and Nanocomposite Advanced Manufacturing/Biomaterials Center, led by Dr. Salem at the South Dakota School of Mines & Technology, will receive $1,806,427 over five years to develop low-cost biopolymers from renewable sources and develop commercially-viable processes for the transformation of these materials into valuable polymers and high performance bio-composites and bio-nanocomposites.
The goal of the Governors Research Center Program is threefold: to develop focused research centers that are competitive for external research funding; to develop and license inventions; and to support existing and spin off start-up companies in South Dakota, said Nathan Lukkes, assistant vice president for research and economic development at the South Dakota Board of Regents.
Since its inception in 2005, the states investment in this program has generated more than $249 million in additional extramural research funding, in excess of 150 invention disclosures, and provided research opportunities for over 940 students, Lukkes said. Additionally, the program has spun out or attracted more than 20 startup companies, which currently employ over 185 people in South Dakota and include such companies as Alumend, SBS CyberSecurity and VRC Metal Systems, to name a few.
The RCC, which is comprised of five public members appointed by the Governor and four members serving by virtue of their position, is charged with oversight and selection of the research centers. The Governors Office of Economic Development and the Board of Regents jointly administer the Governors Research Center Program.
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London tower inferno may have destroyed DNA needed to ID 70 missing victims – Chicago Tribune
Posted: at 1:46 pm
Fifty-eight people who were in Grenfell Tower are still missing and are presumed to be dead, London police announced Saturday, raising the death toll in the horrific inferno that turned the public housing block into a charred hulk.
Public anger is mounting as residents and neighbors demand answers for how the blaze early Wednesday spread so quickly and trapped so many of the tower's 600-odd residents. British media have reported that contractors installed a cheaper, less flame-resistant type of exterior paneling on the 24-story tower in a renovation that was completed just last year.
Police Commander Stuart Cundy said the number of 58, which was based on reports from the public, may rise and includes the 30 deaths that have already been confirmed. He says it will take weeks or longer to recover and identify all the dead at the charred building.
"Sadly, at this time there are 58 people who we have been told were in the Grenfell Tower on the night that are missing, and therefore sadly, I have to assume that they are dead," he said.
Cundy said there may have been other people in the tower that police are not aware of, which would add to the final death toll. He asked anyone who was in the tower and survived to contact police immediately.
Police say the harrowing search for remains had been paused Friday because of safety concerns at the blacked tower but has resumed. Cundy said emergency workers have now reached the top of the tower.
Cundy said police will investigate the tower's refurbishment project, which experts believe may have left the building more vulnerable to a catastrophic blaze.
British Prime Minister Theresa May, facing criticism for the government's handling of the disaster, met Saturday with a small group of fire survivors invited to her official residence at 10 Downing Street. The meeting is unlikely to quell complaints that May has been slow to reach out to victims, despite her announcement of a $6.4 million emergency fund to help the displaced families.
The identification of the victims is proving very difficult which experts attribute to the extreme heat of the fire. British health authorities say that 19 fire survivors are still being treated at London hospitals, and 10 of them remain in critical condition.
A solemn Queen Elizabeth II marked a minute of silence for victims of the London high-rise inferno at the start of a procession Saturday to mark her official birthday. She said Britain remains "resolute in the face of adversity" after the horrendous fire and recent extremist attacks in London and Manchester.
The 91-year-old monarch said it is "difficult to escape a very somber mood" on what is normally a day of celebration.
The queen and her husband, Prince Philip, stood silently on the steps of Buckingham Palace before the start of the Trooping the Color ceremony that each year marks the queen's official birthday, which is traditionally celebrated in June when the weather is warm.
There is simmering anger in the multi-ethnic north Kensington area hit by the blaze, and public fury has been directed at senior government figures, including May, who was jeered Friday after she visited the fire community. Hundreds have been left homeless by the blaze, putting more pressure on officials in a city plagued by a chronic housing shortage.
Scuffles broke out near the Kensington and Chelsea town hall offices Friday as demonstrators chanting "We want justice!" surged toward the doors.
The government has promised a full public inquiry, but that has done little to a sense of frustration at the lack of information about how the fire moved so quickly to engulf the building.
Engineering experts and fire safety specialists believe the building's exterior cladding may have quickly fueled the blaze, overwhelming fire protection devices. British officials have ordered a review of other buildings that have had similar renovations.
The tragedy has provoked a huge response from nearby communities. More than 3 million pounds ($3.8 million) have been raised for the victims. Many of the displaced are living in churches and community centers. There is ample food and water, but very little privacy or proper bedding, and with the tower destroyed, no one knows where they will be relocated or for how long.
Two nearby Underground lines were partially shut down Saturday in the fire area to make sure that debris did not land on the tracks.
Some Grenfell residents had warned months ago fire safety issues at the tower meant that it was at risk of a "catastrophic" event. They say their complaints were ignored and fear it was because the tower was full of poor people in a hugely wealthy neighborhood.
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London tower inferno may have destroyed DNA needed to ID 70 missing victims - Chicago Tribune
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Privacy Concerns Over DNA Tests That Help Discover Your Roots … – NBC 5 Dallas-Fort Worth
Posted: at 1:46 pm
For generations, cross-referencing tombstones at the cemetery and vital records was required to unlock your lineage.
But now, you can easily uncover some of the mystery of your family tree with DNA.
Consumers like Larry Guernsey are giving the service as gifts.
"I thought it would be a good Christmas present," Guernsey said.
The $99 DNA test uses a saliva sample to trace family history.
Here's how one company that provides the service, Ancestry, says it works:
"A simple test can reveal an estimate of your ethnic mix like if you're Irish or Scandinavian, or both."
For Guernsey his curiosity twisted to suspicion once he read the fine print. To proceed, he'd have to give ancestry a "perpetual, royalty-free worldwide transferable license" to use his DNA.
"That entire phrase: 'perpetual royalty-free worldwide transferable,' it sounds like they have left it open to do anything they want with it," Guernsey said.
He was concerned the "transferable license" could put his family's DNA in the hands of an insurance company that could later deny coverage.
"That's not a crazy worry," said Stanford University law professor Hank Greely.
Greely teaches and writes books about the intersection of bio-tech and the law. Greely says medical researchers and pharmaceutical companies routinely need DNA data to develop new products, and companies that have big DNA databases, like Ancestry, sell it to them.
"Some of them get a fair amount of their revenue by selling the analysis of your DNA," Greely said.
NBC 5 Responds asked Ancestry for an interview, but it declined.
In a statement the company said:
"The decisions we make are guided by the basic belief that our customers' data belongs to them."
They went on to say, "We provide every customer options to choose how we may use their DNA data when they sign up .. .We will not share DNA data with third party marketers, employers or insurance companies."
Ancestry's website currently tells users they have a choice to later "delete your DNA test results" or "destroy your physical DNA saliva sample."
Ancestry also says it stores your "DNA sample without your name."
Those statements are posted to its privacy page.
However, they're not in the contract you sign.
"If it bothers you, if it offends, if you're worried about what might be in there, then you shouldn't sign this contract," Greeley said.
Guernsey didn't, and he canceled his order.
So now, the steps to tracing the Guernsey family tree might include an old-fashioned graveyard walk.
Greely noted that DNA tests for genealogy are fairly cheap, perhaps, for a reason the fact that the data is really being sold again down the line.
Published at 10:02 PM CDT on Jun 16, 2017 | Updated at 10:59 PM CDT on Jun 16, 2017
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New York OK’s family-DNA searches for suspects, amid debate – The Seattle Times
Posted: at 1:46 pm
NEW YORK (AP) New York is becoming the latest U.S. state to let police hunt for suspects by identifying their relatives through DNA, after officials voted Friday to allow a practice that authorities call a crime-solver but civil libertarians consider a DNA dragnet.
The technique, known as familial DNA searching, is now expected to be available this fall in New York. The state Commission on Forensic Science voted 9-2 to allow it in murder, rape and some other cases, including times when it could help exonerate someone already convicted.
Spokeswoman Janine Kava says the new policy will provide law enforcement with a proven scientific tool to help investigate and solve serious crimes.
Authorities have for decades found suspects by matching crime scene evidence to convicted offenders DNA. Familial DNA testing comes into play when theres no match. It looks instead for people similar enough to be closely related to whoever left the crime scene DNA. From there, investigators can look for family members who fit as suspects and, if they find one, pursue enough other evidence to bring charges.
At least 10 other states and some other countries use familial searching. It has borne fruit in such high-profile cases as Los Angeles Grim Sleeper serial killings and the 1976 killing of the ex-wife of Righteous Brothers singer Bill Medley, also in Los Angeles.
Proponents see familial searching as a potent source of leads that can be done precisely and fairly.
The process also helps exclude the innocent, and safeguards are in place so that the searching is done prudently and the information is used discreetly, said state district attorneys association president Thomas Zugibe, whos the DA in suburban Rockland County. Under New Yorks new policy, the state criminal justice services commissioner would review every familial DNA searching request, and investigators couldnt see the results without training on how to evaluate them.
While authorities praise the technique, defense lawyers and civil liberties advocates decry it for entangling law-abiding people in investigations because of their family ties. At least two jurisdictions, Maryland and Washington, D.C., have prohibited the practice, and the Legal Aid Society said Friday it was considering legal action or a legislative campaign to stop it in New York.
Civil rights and privacy lost with todays vote, said Tina Luongo, an attorney with the society.
The commission began considering the issue last fall, when prosecutors wanted to use familial DNA searching in the case of Karina Vetrano, a 30-year-old killed while out running in New York City last August. Ultimately, police zeroed in on suspect Chanel Lewis through other means and then got a DNA sample from him that matched material under Vetranos nails and at the crime scene, they said. Lewis has pleaded not guilty to charges including murder.
Although familial searching didnt factor in Vetranos case, her father applauded Fridays vote.
Many families will benefit, and many criminals will suffer, Phil Vetrano wrote on an online reward-fund page. We will always be grateful to Karina for this.
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Researchers send DNA on sequential building mission – Phys.org – Phys.Org
Posted: at 1:46 pm
June 16, 2017 by James Devitt A team of scientists has developed a method to create structures whose building blocks are a millionth of a meter in size by encoding DNA with assembly instructions. In a series of experiments, the researchers mixed four "flavors" of droplets (yellow, orange, green, and blue), each coated with different DNA, but which do not bind. They then added a new droplet (red), which specifically binds to the orange droplet and activates it for the next step in the assembly. This process spurs the creation of a droplet chain in a pre-determined order (red-orange-yellow-green-blue). Credit: Yin Zhang
A team of scientists has developed a method to create structures whose building blocks are a millionth of a meter in size by encoding DNA with assembly instructions.
The work, described in the journal Nature Communications, manipulates the sequencing of DNA to offer an intricate and innovative approach to synthesize materials at the most fundamental level.
"Sequential programmability is a powerful addition to the self-assembly toolbox that will prove useful in creating the tiniest of materials," explains Yin Zhang, the paper's lead author and a graduate student at New York University's Center for Soft Matter Research. "It brings some of the advantages of the biological use of controlled sequential assembly using molecules, nucleic acids, and proteins to a new design scale."
NYU physics professors Paul Chaikin and Jasna Brujic as well as Nadrian Seeman, an NYU professor of chemistry, co-directed the research.
Both natural and human-made structures are built sequentiallyfrom cells to skyscrapers. Like Russian nesting dolls, assembly takes place on the inside before commencing on the outside.
However, when making materials on a micrometer scale, or about one hundredth of the width of a strand of human hair, scientists face challenges unfamiliar to engineers and manufacturers.
While many methods have been adopted to manipulate such tiny particles, these approaches all have notable shortcomings in assembling structures.
The NYU team sought to overcome these hurdles with a new approach: encode the instructions of assembly within the building blocks and let these building blocks self-organize into a prescribed structure in a pre-determined sequence.
To do so, it deployed different strands of DNA, each coated on a droplet of oil in water, where they then "talked" to each other through DNA-mediated interactions. Specifically, the scientists placed four "flavors" of dropletslabeled B, C, D, and Einto water. They then added an "initiator" droplet, A, which began the sequencing process. Here, the DNA strand on A initiates a chain of events in which it displaces one of the paired strands on B, whose released strand moves to activate C, the next droplet in the sequence, and so on. The process results in a droplet chain, ABCDE.
Explore further: Chemists color world of 3-D crystals with advances in self-assembly
The wide reach of corrosion, a multitrillion-dollar global problem, may someday be narrowed considerably thanks to a new, better approach to predict how metals react with water.
A team of scientists has developed a method to create structures whose building blocks are a millionth of a meter in size by encoding DNA with assembly instructions.
A team of researchers at Sungkyunkwan University in South Korea has developed a type of adhesive patch that works under a variety of conditions including underwater. In their paper published in the journal Nature, the team ...
Javier Vela, scientist at the U.S. Department of Energy's Ames Laboratory, believes improvements in computer processors, TV displays and solar cells will come from scientific advancements in the synthesis of low-dimensional ...
A team of researchers at the University of Pennsylvania is gaining new insight into the smart materials used in ultrasound technology. While forming the most thorough model to date of how these materials work, they have found ...
Researchers have developed a solar paint that can absorb water vapour and split it to generate hydrogen - the cleanest source of energy.
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DNA leads to burglary arrest – Times Daily
Posted: at 1:46 pm
FLORENCE A Tennessee man has been arrested on burglary charges after his DNA was found at a business that was broken into last year.
James Bullock, an investigator with the Lauderdale County Sheriffs Office, said Marcus Orlandus Brown, 31, Covington, Tennessee, is charged with third-degree burglary, first-degree theft of property, first-degree criminal mischief and first-degree receiving stolen property.
Bullock said Brown is charged in connection with the Jan. 25, 2016, burglary of Haddocks Quick Start on Alabama 20 in the Central Heights community.
Bullock said Brown was arrested in Memphis and transported back to Florence.
He said DNA, left at the scene, was recovered along with other evidence during the course of the investigation.
The DNA sample was sent to the Alabama Department of Forensics to be analyzed and it got a positive hit.
And they determined the DNA at the business belonged to Marcus Brown, Bullock said.
Brown is out of jail on bail of $11,000.
Bullock said the case remains under investigation as authorities search for two other suspects.
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Genome pioneer John Sulston enters elite club – BBC News – BBC News
Posted: at 1:46 pm
BBC News | Genome pioneer John Sulston enters elite club - BBC News BBC News Sir John Sulston is elevated to the Companion of Honour in the Queen's birthday list. Birthday Honours: gongs for Cambridge genome scientist John ... Cambridge scientists among those honoured by Queen | Anglia ... |
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Are genome-wide association studies fundamentally flawed? – MedCity News
Posted: at 1:46 pm
MedCity News | Are genome-wide association studies fundamentally flawed? MedCity News From 5,000 to 10,000 to one million and beyond. The scale of so-called genome-wide association studies (GWAS) has grown at a voracious pace over the last decade. And there's no sign the initiatives are slowing down. As sequencing and data analysis ... |
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This Study is Forcing Scientists to Rethink the Human Genome – Gizmodo
Posted: at 1:46 pm
The more data, the better, right? When it comes to genetics, it turns out that might not be the case.
As both genetic sequencing has gotten cheaper and computerized data analysis has gotten better, more and more researchers have turned to what are known as genome-wide association studies in hopes of sussing out which individual genes are associated with particular disorders. The logic here is simple: If you have a whole lot of people with a disease, you should be able to tell what genetic traits those people have in common that might be responsible. This thinking has resulted in an entire catalogue of hundreds of research studies that has shed light on the genetic origins of diseases such as type 2 diabetes, Parkinsons disease, Crohns disease, and prostate cancer, while helping fuel the rise of personalized medicine.
Now, though, a new analysis calls the entire approach into question.
Writing in the journal Cell, a group of Stanford University geneticists write that such large studies are likely to produce genetic variants with little bearing on the disease in questionessentially false positives that confuse the results.
Intuitively, one might expect disease-causing variants to cluster into key pathways that drive disease etiology [the causes of disease], they write. But for complex traits, association signals tend to be spread across most of the genomeincluding near many genes without an obvious connection to disease.
Their analysis suggests an intriguing new way of viewing the genome in which nearly every gene impacts every other gene. Instead of a system in which you can plug and play different variables to affect different results, its a complex, inter-related network. They call this the omnigenic model.
Their work has broad, sweeping implications for the entire field of genetics. First off, that all those big, expensive genome-wide association studies may wind up being little more than a waste of time because they turn up genetic variants that, while perhaps interconnected to the disease, may not actually point to a viable target for things like drug therapy.
Indeed, genes that often seem related to diseases have stumped researchers in terms of the role they actually play in the condition. In the paper, for example, the Stanford researchers re-analysed a 2014 study of 250,000 people which found nearly 700 DNA variants linked to heightbut only 16 percent of these variants had anything to do with a persons height. In the paper, the Stanford researchers suggest that the impact of each variant has a teeny impact on height.
Far from solving a problem though, this new research merely opens up an entirely new line of questioningand shows us once again, that we may not know nearly as much as we thought we did.
[Cell]
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This Study is Forcing Scientists to Rethink the Human Genome - Gizmodo
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