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Category Archives: Transhuman News
Musicians pay the price for playing politics – The Zimbabwe Standard
Posted: July 2, 2017 at 8:44 am
The song, The Blair That I Know Is a Toilet by forgotten musician Last Chiyangwa aka Tambaoga was at some point a hit and the musician was the darling of many, among Zanu PF supporters.
By Kennedy Nyavaya
Tambaoga
There was no Zanu PF gathering that Tambaoga would not perform from national galas to rallies and he was a regular feature on national radio and television which then were championing the 75% local content policy.
However, a few years down the line, Tambaoga found himself falling into the abyss because of his widely-perceived political alignment to Zanu PF. He even tried to resuscitate his career in 2009 when he released an album titled Hakata, but there were no takers.
He pleaded with music followers to accept him as an artist, not a politician but no one listened to him and that marked the demise of his transitory music career.
However, it appears local musicians did not learn anything from his experience.
Last month Zimdancehall chanter Soul Jah Love was dressed down by a Zanu PF party official at a rally in Mutare, an incident that attracted an uproar from different social circles with people airing disgust at the way their superstar had been treated.
Social media went ablaze with different memes and comments alluding to the brief incident when Soul Jah Love was addressed like a nonentity.
Indeed the words used by the politician towards the chanter were harsh and unsolicited, but the response from the public appeared more politically-inclined than anything.
Yet, instead of vindicating the politician the new question is whether or not Soul Jah Love and other artists billed to perform on that day should have been at the event in the first place?
Looking at the history of politics in post-colonial Zimbabwe after year 2000 it has always been suicidal to mix music with politics, said a veteran musician who refused to be named fearing reprisals.
As soon as the countrys political landscape changed around year 2000 it became suicidal to do political music, no matter which side you are.
He singled out musicians such as the late Simon Chimbetu, Andy Brown, Marko Sibanda and Tambaoga as some of the artists who became unpopular after dining with Zanu PF.
The musicians penned songs that were pro-Zanu PF and enjoyed a lot of airplay and slots to perform at national events while their fan bases shrank.
According to the veteran musician singing against the Zanu PF government may not be so much of a good idea as well because it damages other aspects of an artists reputation.
Being denied airplay and good media coverage from State media weakens brands as seen by Raymond Majongwe, Paul Madzore and Leonard Zhakata among many others, he said.
During the colonial era singing against the Rhodesian government could get one arrested or their music could be blacklisted and not played on radio but it did not affect ones followership as the majority were the oppressed black people.
With divergent political views the reality has changed and choosing particular political inclination may create hatred from some sections of the music fraternity.
However, as the 2018 elections beacon, the country is slowly getting into the polling mode and politicians are giving it all for political expediency.
One of the effective drawcards political parties are using is free entertainment through music, especially at rallies.
There is no doubt that politics and entertainment are intertwined in Zimbabwe dating back to the colonial era as musicians played an integral part in the liberation war.
But, for musicians direct engagement with modern politics has proven to have negative repercussions.
Even youthful music groups like Born Free Crew are testimony that political alignment compromises ones relevance off politics.
Last year Oliver Mtukudzi found himself in the middle of a political storm after he performed at the ruling partys One million Man March.
Tuku is a musician and ekes a living through singing. If he performed because of that I dont see anything wrong, but he could have performed out of fear, veteran musician Hosiah Chipanga defended him then.
Chipanga, who is also a victim of political seclusion, went on to suggest that the jazz icon could have performed under duress fearing the wrath of the fist had he not agreed.
Being a Zimbabwean, he knows how to deal with Zanu PF. He knew what could have been done to him if he had turned them down. Saka unongotamba iyoyo iri kurira. [You dance according to the tune], he told The Standard Style.
When asked if he would have performed at a Zanu PF event, had he been invited, Chipanga who used to perform at galas said his presence back in the day was influenced by money.
He also explained how he fell out of favour when he started singing politically incorrect lyrics.
The same trend characterised the South African scene earlier this year with the ANC party giving musicians who professed their support time at their events but the local situation has proven special as it has other underlying influencing factors apart from personal conviction.
In a difficult economic situation the arts like any other sector has suffered as a result of diminished funding and reducing buying power among citizens and that has presumably encouraged artistes to jump at all opportunities.
While the events present opportunities for a quick buck for musicians, they have assisted in dividing fan bases in some cases and ultimately it is the artiste who faces the sour consequences while the cunning politicians occupy positions of influence.
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Musicians pay the price for playing politics - The Zimbabwe Standard
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Let’s get the band back together for Chicago trip – Dothan Eagle
Posted: at 8:44 am
With the disappearance of freedom of speech and fun, the recent rash of alleged, politically-incorrect, insensitive comments, and subsequent apologies, retractions and job losses, the pre-Independence Day column written for today has ceased to be.
Instead of reading this spaces usual drivel, youre on your own until further notice.
As the late Edward R. Murrow signed off newscasts, Good Night and Good Luck.
Dont know how Murrow and the CBS newsmen he assembled during/after World War II, including Troys Douglas Edwards, would handle social media, Instagram, Internet, YouTube, cell phones, lovers, truckers and thieves, ad nauseum, while ever-increasing coveys of moronic-aspiring twitters, from almost every walk of life, seemingly cant wait for their tweeters to leap into their cash registers.
Its sorta like Archie Campbells 1964 song, RinderCella, the youngest, prettiest sister who slopped her dripper.
Hard to believe, some of us baby bloomers(!) have long revisited the Summer of Love, aka 1967, while others continued happily motoring along, without looking back, attending class reunions and/or regretting mistakes made 50 summers ago.
Comedian Charlie Fleischer is credited by many for saying, If you can remember the 60s, you really werent there.
Maybe thats right for some; others of us with memories are extremely thankful for six magical words concerning the 60s: The statute of limitations has expired.
Whether and how well celebrate this July 4 aint decided, but on July 4, 1967, some 64 members of Enterprise High Schools Wildcat Marching Band celebrated involvement in the Summer of Love, in Chicago, where we represented Alabama at the 50th anniversary Lions International Convention.
Summer of Love seeds were sown in and around San Francisco in early January 67, and by summertime, more than 100,000 hippies, many festooned in vibrant paisleys, rallied at the Haight/Ashbury confluence, near where, in musically-magic 62, pre-Lady Gaga Tony Bennett had left his heart.
Long before 67s summers solstice, as it turned out, wed over-prepared afore boarding two chartered Greyhound buses for the 23.5-hour trip to Chicago; our contribution to the four-hour parade would be short and sweet.
Kris Holzapfel had provided, arguably, the highlight of our trip north when, unbeknownst to others, he sneaked a candy bar, Sessions Co. had given us, into the buss bathroom, where he stayed and stayed.
When Kris emerged, wed already noticed hed daubed chocolate specks all over his face before he suspiciously complained, ahem, about rough roads as we sped across rural Indiana and its historic Wabash River.
Simultaneously, some 50,000 Lions Club members from everywhere (thats the International part, Neal) had begun arriving in Chicago July 3, ready for numerous festivities, including the parade, which began on Michigan Avenue at Wacker Drive, and headed south some 14 blocks, ending at 9th Street.
Itd take this entire newspaper to rehash that unforgettable trip, but for 12 of us our leader, the late Bob McMillan, dubbed the Dixie Dozen, one day we played 17 venues, as the crow flies, throughout the Palmer House, Pick Congress and Conrad Hilton hotel convention venues.
Played Dixie every set and while strolling Michigan Avenue.
Since the 67 Lions gathering was the 50th, must mean thisuns the 100th and its in Chicago.
Wish now wed done what Ellwood and Jake Blues did, you know, get the band back together.
The convention runs through Tuesday.
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US finances wars through inflation: Ron Paul – Press TV
Posted: at 8:42 am
The United States finances wars through inflation and that most wars are fought on inflated money, according to former US Congressman and political analyst Ron Paul.
Dr. Paul, a three-time American presidential candidate and the founder of the Ron Paul Institute for Peace and Prosperity,made the remarks in an interview on Friday while discussing US monetary policy and the need for a better system centered on sound money.
The senior American statesman said that from diluting gold in coins and clipping coins in the old days to using a computer to create new US dollars today, financing war through inflation is traditional.
If the people had to pay for the war as we went along, it wouldnt happen. You dont get enough taxes, you dont get enough borrowing to fight these wars, he stated.
And we have the license to steal because we issue the reserve currency of the world. And most of the countries still accept our dollar, even though were currently witnessing, in the last few days, a pretty steady attack on the dollar which I think is going to continue, and of course might get much worse, Dr. Paul said.
The money issue is a freedom issue, because if you dont like the welfare state you have to understand about money, if you dont like the warfare state, you have to understand that about money, he added.
If you care about individual, personal liberty you would have to be a supporter of a commodity...currency, of course, the history shows has always been gold along with silver -- the most preferable type of money, he observed.
The Fed, the source of trouble
Dr. Paulhas maintained strong positions against the military-industrial complex and the Federal Reserve, each of which he considers responsible for many of the ills afflicting the United States.
The basic source of the economic trouble is Americas central banking system, known as the Federal Reserve or the Fed, which cannot function in a real market economy, he once said.
In a true free market economy you have to have people work, use what they need to live on and then save money, and that dictates interest rates and tells businessmen what they should do. Well, that isnt the way it works anymore, the veteran former politician said in an interview in 2015, and warned that the biggest economic crash ever would hit the American economy.
The so-called capital comes from the Fed and they create it out of thin air. So everything is a mistake and everything is going to be volatile, he observed.
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Living to 125 and beyond: Scientists dispute there’s a limit to – KMOV.com – KMOV.com
Posted: at 8:42 am
(CNN) -- Don't mess with our collective dreams of immortality. A flurry of new research vigorously opposes a study from last year that dared to suggest there might be a ceiling to the human lifespan.
In onenew paper, Dutch scientists predict that, by 2070, our lifespan may increase to 125 years while beyond that, the sky may be the limit. Their analysis was published Wednesday in the journal Nature.
The debate over hisoriginal paper, published last October in Nature andwidely reported by CNNand other media outlets, took Jan Vijg, senior author, by surprise.
For a biologist, a natural limit to the lifespan "makes a lot of sense, so that's why I never imagined the paper would stir up so much comment," said Vijg, a professor at Albert Einstein College of Medicine in New York.
To prove a 125-year lifespan is possible, researchers from the Netherlands Interdisciplinary Demographic Institute team began their study by refuting the relationship between age and immortality posed byBenjamin Gompertz.
This 19th-century mathematician pored over mortality data and noticed that young people have a very low chance of dying. Yet, in middle age, the chance of dying increases and then rises again dramatically in old age.
This exponential increase in the rate of human mortality has long been accepted wisdom, yet the Dutch researchers decided to challenge it. Instead of basing their work on data derived from the general population, they used data from a group of people noted for their long lives -- Japanese women.
Using mathematical models, they claim mortality goes down in old age and projected an astounding new human lifespan -- 125 years -- will be achieved by 2070.
Along with this theory, an additional four separate papers poke holes in Vijg's work. ACanadian teamof scientists claims Vijg's original paper is based on statistically "noisy" (or meaningless) data. Meanwhile, a research team from theUniversity of Copenhagenargues that any inferences about lifespan potential are premature; a team from theMax Planck Instituteclaims there's simply no evidence of a "looming limit;" and a team from theUniversity of Groningenoffers four cohesive arguments contesting the conclusions drawn by Vijg's team.
What inspired this heated debate?
In their paper, Vijg and his graduate students, Xiao Dong and Brandon Milholland, analyzed aging trends in the United States, the United Kingdom, France and Japan.
Vijg explained that their analysis was based not on some mathematical model that projected future data, but on "actual data" of real human lives. They examined not one but two different data sets, and what they observed was that, despite life expectancy being dramatically higher than it was 100 years ago, the probability of anyone living for more than 125 years was unlikely.
"Initially, you see this increase every year and you see this oldest record holder until the 1990s, and then it stops," said Vijg. "Think about it, how strange it is."
The number of healthy centenarians increased dramatically every year. That being the case, Vijg theorized "the supply is certainly there" to create more record-breakers, every year, yet there were none.
Vijg wondered, "How is that possible?" A decades-long plateau following years of new old-age records must mean humans have reached the lifespan limit, he and his colleagues concluded.
It is a rather logical conclusion for biologists, who have long seen that individual animal species each have a particular span of time in which they are born, develop into maturity, and then die, Vijg explained.
"WhenJeanne Calmentdied, I really thought that this was the beginning of something very dramatic," said Vijg. Jeanne Calment died in 1997 at age 122, which remains "the greatest fully authenticated age to which any human has ever lived," according toGuinness World Records.
Hearing about Calment's long life, Vijg rebelled against the accepted wisdom that lifespan "must be fixed, it must be like a ceiling."
Yet, testing the theory, Vijg and his co-authors found no fresh old-age record breakers. Sure, the Canadian scientists who created a mathematical model found random plateaus, some seven years long -- but still their research fails to explain a plateau of decades, said Vijg.
The Canadian scientists may believe their research disproves his, but instead, it "is a beautiful confirmation of what we found," he said.
"They want us to be wrong," said Vijg, who with his colleagues published arebuttalto all the criticism. "I can see that it's very depressing when you find out that we can never get older than 115 years on average."
Vijg, though, is not a depressed man.
He says he's seen the tremendous strides made in all scientific fields as well as technology and hopes that someday the aging process might be halted.
"We may be able to do that at some point, as I say, by the way, at the end of my paper," said Vijg. "But if we are not able to do that because aging turns out to be still very mysterious, or a process that we cannot really intervene with, then we are stuck with a real maximum lifespan that fluctuates around 115."
"Accept it," he says.
The-CNN-Wire & 2017 Cable News Network, Inc., a Time Warner Company. All rights reserved.
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Transhumanism just another ‘religion’ in which man seeks to become God – WND.com
Posted: at 8:41 am
An intelligence so capable it can perceive every cause and effect. The promise of eternal life. The dawn of a new age in whichsuffering will be eliminated, every need will be met and the individual will find fulfillment by subordinating himself to something far greater than himself.
These are the promises of most great faiths. The capacityto understand and predict everything thatcould possibly occur is a characteristic most would ascribe toGod.
But today, thisrhetoric surrounds an ostensibly scientific and secular movement. Transhumanism, the attempt to overcome the bodys limitations through technology, and the hunt for artificial intelligence are promoted with evangelistic language.
Around the world, heavily funded by billionaire philanthropists, researchers are probing whether aging can be curbed or even prevented, just like any other disease.
Indeed, scientist Aubrey de Grey, chief science officer of the SENS Research Foundation, argues the biggest obstacle to immortality is simply a lack of funding to fuel research.
Even dissident and Wikileaks head Julian Assange confidently predicted de facto immortality would soon exist because people would upload their consciousness to an artificial intelligence and live forever as part of a simulation.
Its like a religion for atheists, Assange said.
Assange is not alone in identifying the fundamentally religious impulse behind the movement. In a recent piece at Aeon a digital magazine on science, philosophy, society and the arts Beth Singler of the Faraday Institute for Science and Religion pointed out how despite itsscorn for religion, the AI community often sounds like a group of believers in a coming god.
[B]elievers in a transhuman future in which AI will allow us to transcend the human condition once and for all draw constantly on prophetic and end-of-days narratives to understand what theyre striving for, she writes.
The community has also generated thought experiments in which the singularity, the creation of artificial intelligence thatwill spark runaway growth, is framed as something akin to the formation of a god. For example, Rokos Basilisk posits an AI which, because it would conceive of itself being able to provide the greatest good for the greatest number, would actually punish humans, even after death, who do not labor to bring it into existence.
Joseph Farah, founder of WND and author of The Restitution of All Things, argues secularists and scientists who seek to escape the need for God ultimately and inevitably find themselves groping back towards the divine.
Theres an old saying, If you dont believe in something, youll believe in anything,' he said. Theres an absolute, fundamental need for human beings to believe in something.
If its not the God, it will be a god. Transhumanists offer an alternative god. You can be like God, the old lie the serpent told Eve in the Garden. You can still have eternal life apart from serving God and obeying His commandments. Its as simple as that. Transhumanists are peddling that kind of lie, again, so naturally they would have their own doctrines, gospel story, creation story, etc.
Ultimately, Farah maintains transhumanism and the quest for immortality, despite its supposedly secular orientation, leads to anti-Christian spiritual and even demonic connotations.
Absolutely, I think thats implied in the way this plays out, he said. Its about living forever. We all know these bodies wear out over time. But you can conquer death. Thats a spiritual idea and it comes from Gods consistent message to us. Its hardwired into our fallen genetic material. And, I believe it is at least inspired by the father of lies.
Its the book that gives you tomorrows news today! Get your autographed copy of The Restitution of All Things: Israel, Christians and the End of the Age.
Mark Biltz, the discoverer of the Blood Moons phenomenon and the author of Gods Day Timer, pointed out the term transhuman ultimately came out of religious literature.
He pointed to an article in the London Guardian profiling how a former Christian fell into transhumanism.The very word first appeared not in a work of science or technology but in Henry Francis Careys 1814 translation of Dantes Paradiso, the final book of the Divine Comedy, Biltz noted.
Dante, in this passage, is dramatizing the resurrection, the moment when, according to Christian prophecies, the dead will rise from their graves and the living will be granted immortal flesh, he said.
The vast majority of Christians throughout the ages have believed that these prophecies would happen supernaturally God would bring them about, when the time came. But since the medieval period, there has also persisted a tradition of Christians who believed that humanity could enact the resurrection through science and technology.
Whats amazing to me is how transhumanists are not just made up of atheists exclusively but Christian involvement has been growing exponentially, he said.
It is hard to believe how this is coming into mainstream Christianity! Indeed, there is even a Christian Transhumanist Association, headed by a preachers kid who was saturated in the Bible and Christian thought but has identified as a transhumanist since the mid-90s. He states in an article in Vice that we may see the next wave of Christians embrace transhumanist technologies as part of a sacred duty to participate with God in the redemption of the world.'
Biltz says he is troubled by such theological innovations.
When I read this I see how the deception of Christians in these last days will be so persuasive, he said. Christians are like the proverbial frogs in the boiling water. Believers need to get on Gods calendar so they realize we are at the time in history were we really need to be looking up, for our redemption draws nigh. Man has always wanted to become god or at least create a god in their own image. This just demonstrates how close we are to the coming of the Messiah.
The Bible story is more miraculous and astounding than you could have imagined. See the incredible proof of the unchanging nature of God and the exciting clues to what awaits at the end of days in Gods Day Timer by Mark Biltz, available as a book or documentary now in the WND Superstore.
Joel Richardson, the New York Times bestselling author of The Islamic Antichrist and Mystery Babylon, believes what is occurring is part of an old pattern in human behavior.
Mankind is essentially religious, whether they will admit it or not, he explained. If someone claims to deny the one, true God of the Bible, and every other god, they will inevitably find another created object to worship, most often themselves.
Richard said the Silicon Valley techno-gods of our time are among the most arrogant and most overt of the self-worshippers.
Perhaps understandably so. Never before in human history has technology and particularly the kinds of technology that is just on the horizon, so deeply challenge not only the essence of what it means to be human, but also our very perception of what it means to be God, he said.
Because of technology, mankind is entering a very dangerous spiritual phase of its existence. The tower of Babel is once again being erected. Those who are at the vanguard of these technologies, though denying true religion, understand the fundamentally religious nature of their work. This is why you will find so much of their work enshrouded in such religious language.
Richardson argues all of this was foretold in the Bible.
As always, it is mankinds arrogance that is his undoing, he said. Ultimately, these are those who the apostle Paul spoke of long ago when he said, that though they self-profess to be wise, they become fools, darkened in their understanding. After all, we all know how the story of the Tower of Babel ends. There is only one true God. He is the one who once warned, Though you say you are gods, you will die like mere men.'
One of the greatest mysteries in Scripture solved at last! Discover the terrifying truth behind the shadowy identity of one of the greatest horrors of the end times. New York Times bestselling author Joel Richardson reveals the secret of Mystery Babylon, available now in the WND Superstore.
Jan Markell of Olive Tree Ministries suggests transhumanism is comparable to the theory of evolution in how it assertsknowledge will evolve to a higher level likely without God.
Man just has to play God or at least be godlike, she said. This advancement comes through cloning and genetic manipulation. Transhumanists look to the future and believe the human condition will see improvement in physical ability, lifespan, mental acuity and health. In addition, the world conditions can also be improved. Such technological advancements, some have said, would even redefine what it means to be human.
It says in the Bible that knowledge will increase. It doesnt suggest this knowledge will be used to good or evil, but I believe, like everything else today, man is trying to be like God. Man will abuse this increase in knowledge and understanding. Thus, transhumanism is almost a religion in itself.
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Pastor Carl Gallups, who examines current headlines in the light of end times prophecy in his book When The Lion Roars, argues the reason transhumanism so closely resembles a religion is because it was predicted in the Bible itself.
From the Garden of Eden to the book of Revelation we watch the story unfold, and the prediction that humankind would eventually, near the return of Jesus Christ, accept the very same lies that started in the Garden, the pastor explained.
Those lies can be summarized as: Man can be God-like, man can live forever without obeying Gods morality code, and therefore man can create God, life and morality in his own image, rather than the other way around. This is exactly what the transhumanists imagine themselves doing. Thus they are in a constant dilemma of trying to explain exactly what it is they are up to without falling into biblical language and imagery. If this scenario wasnt so clearly predicted thousands of years ago, complete with the somber results that are soon to come, it would almost be comical.
Gallups warned transhumanists are pursuing something the Bible warned about in the last days.
Even the transhumanist prophets predict an ultimate and soon-coming intelligence that will surpass any human capability perhaps even leading to unthinkable brutality, the pastor said. They even admit that what they are up to is, ultimately, rebellion against human existence as it has been given. Again, exactly what the Bible predicted. Demonically, that intelligence, rebellious spirit and brutality will manifest itself in the personage of the Antichrist. Transhumanists are not only saying basically the same thing as the Bible but are actually working feverishly to usher in the same biblical predictions they mock.
Gallups said ultimately Christians have a choice: whether they will place their faith in the promises of technology or the prophecies of Scripture thatseem to be predicting exactly whats happening today.
Which came first, the Word of God and the lies of the Garden of Eden or the modern transhumanists pursuit that matches the Bibles description of the last days? The answer is so obvious that apparently even some of the transhumanists see it the Word of God and its prophecies came first. Therefore, Im sticking with the original source, Gods holy Word.
Extraordinary events predicted centuries in advance are unfolding now. Here is your guide to the incredible prophecies being fulfilled before our very eyes. Dont miss the bestselling sensation from one of Americas most prolific and beloved pastors. When the Lion Roars: Understanding the Implications of Ancient Prophecies for Our Time by Carl Gallups, available now in the WND Superstore.
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Trump appoints anti-trans activist to key human rights post – LGBTQ Nation
Posted: at 8:41 am
Donald Trump with daughter Ivanka, who several months ago some people were predicting would be a moderating force in the White House, especially on LGBTQ issues. Wikimedia Commons
Donald Trump has appointed a person whose most recent work was activism against transgender rights to be the senior adviser for womens empowerment in the US Agency for International Development (USAID).
USAID is an independent agency that administers foreign aid programs, including poverty and disaster relief programs.
Bethany Kozma worked for the Department of Homeland Security under George W. Bush. In 2016, she started the United We Stand campaign to end Barack Obamas protections for transgender students.
In a post to a publication run by the anti-LGBTQ Heritage Foundation, Kozma wrote, To put it simply, a boy claiming gender confusion must now be allowed in the same shower, bathroom, or locker room with my daughter under the presidents transgender policies. When I learned that predators could abuse these new policies to hurt children in school lockers, shelters, pool showers, or other vulnerable public places like remote bathrooms in national parks, I realized I had to do something.
A video accompanying the article shares stories from women who were sexually assaulted in locker rooms and bathrooms by cisgender men who did not need anti-discrimination measures to enter those rooms. Those stories are presented as reasons to discriminate against transgender people.
She went on to accuse LGBT activists of bullying everyone including her childrens vice principal into silence, because one of the rightwing trolls favorite games is I know you are but what am I, where they use tortured logic to accuse the oppressed minorities of doing the exact things that oppressors do.
When the Trump Administration reversed the Obama Administration guidance on transgender students, effectively setting up conditions for more transgender students to be bullied at school and denied an education, Kozma wrote that she was thrilled.
USAID has backed programs intended to increase LGBTQ peoples access to housing, health care, and political participation. USAID also has guidelines preventing contractors it works with from discriminating on the basis of sexual orientation and gender identity. The agency told BuzzFeed News that the agency is still committed to those programs and policies.
It is unclear what exactly Kozma will do in her new position, but its safe to say that she will not be advocating for all womens empowerment.
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This New Gene-Editing Technique Can Spot CRISPR’s Mistakes – Futurism
Posted: at 8:40 am
In BriefScientists have developed a tool that can test an entiregenome against a CRISPR molecule to predict potential errors andinteractions. This will allow doctors to ensure treatments aresafer and more effective. Editing The Editor
The CRISPR gene-editing tool is already in use by scientists all over the world who are racing to cure deadly diseases by editing the genomes of patients. However, as human trials for various treatments are slated to begin, we still face the hurdle of ensuring that any errors in CRISPR edits wont causing problems. Scientists from The University of Texas at Austin may have come up with a possible solution. Theyve developedsomething that works like a predictive editor for CRISPR: a method for anticipating and catching the tools mistakes as it works, thereby allowing for the editing ofdisease-causing errors out of genomes.Click to View Full Infographic
Scientists have already learned how to use CRISPR to edit errors in almost any genome and its these errors that can cause a wide range of diseases. Many forms of cancer, Huntingtons disease, and even HIV can be targeted usingCRISPR. That being said, itsnot a perfect solution. Just as the autocorrect on your smartphone can cause you to send an unintentional and embarrassing text message, CRISPR can correct something that was actually right the consequences of which can make it adangerous mistake. One that actually causes a disease as opposed to an embarrassing social gaffe.
The researchers developed a method for quickly testing a CRISPR molecule against a persons entire genome, rather than onlythe target area,in order topredict other segments of DNA the tool might accidentally interact with. This new technique functions like an early warning system, giving doctors a chance to more closely tailor gene therapies to specific patients, while ensuring they are effective andsafe.
If were going to use CRISPR to improve peoples health, we need to make sure we minimize collateral damage, and this work shows a way to do that,Stephen Jones, UT Austin postdoctoral researcher and co-lead author of the study, told the UT News.
This research will also allow scientists to improve their own predictive skills when it comes to CRISPR molecule behaviors even without genome testing. This is because the work is actually revealing the rule book CRISPR molecules follow when they choose targets.
One CRISPR molecule the team tested, Cascade, targets DNA sequences but pays less attention to every third letterin the sequence. So if it were looking for the word shirt and instead found the word short, it might be fine with that, Jones said, explaining the significance of the quirk to the UT News.
As researchers master these rules, they will be able to develop better predictive models for CRISPR therapies. This will make the technique faster and cheaper, which will in turn render personalized gene therapies more accessible to more patients. Most important of all, it will also help make theentire process far safer.
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Scientists Want to Genetically Engineer Heat-Resistant Cows to Survive Climate Change – Futurism
Posted: at 8:40 am
In Brief A federal grant has enabled researchers to investigate what makes the Brangus cow so effective at body temperature regulation. Due to climate change, high temperatures have made trouble for cows, leading to decreased efficiency and quality in agriculture. Can Cows Take the Heat?
The University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) has proposed a plan to make cowsmore resistant to the temperature increase caused by global warming. The proposal has received a three-year, $733,000 federal grant.
The scientists plan aimsto retain the quality meat cows provide whileincreasing the efficiency of the process in spite of a changing climate. The first step is conducting research on cows that already handle the heat pretty well. By studying theBrangus cow, researchers hope to identify how it regulates its body temperature, which allows it thrive in hotter climates. Once identified, researchers could usea gene editing tooltogive thatability to other breeds.
Dr Rachel Mateescu, associate professor in the UF/IFAS department of animal sciences, told Digital Trends:
Heat stress is a principal factor limiting production of animal protein and negatively affecting health and welfare of cattle in subtropical and tropical regions, and its impact is expected to increase dramatically due to climate change [] the ability to cope with heat stress is imperative to enhance productivity of the U.S. livestock industry and secure global food supplies.
That a venture like this received funding is a sign of two things that many in the scientific community have been well aware of, but that they may not have yet connected:the rate at which the climate is changing, and the potential of gene editing software.
Climate change isfundamentally changing our world.Its even changingthe genetics of several species including humans as well as altering the function of entire ecosystems.
As funding for this research is contingent on viability, its also a chance to demonstratethe rapid progress made in gene editing software, which has been catalyzed by CRISPR. Since its first demonstration in 2013,an enormous amount of research has been conducted using it. The future of gene editing with CRISPRs help looks bright, too: manytrials have or are set to beginthis year, including attempts to modify viruses to killantibiotic resistant bacteria andrevive extinct species.
While it seems more logical to reduce global warming rather than try to deal with its consequences, should the preventative method fail, the only solutions that we could turn to are those previously reserved for the realms of science fiction, like changing ourgenetic makeup or migrating to another planet.
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New Study Says This Region of the US Will Be Hit Hardest by Climate Change – Futurism
Posted: at 8:40 am
Enhanced Regional Inequalities
A new study from the Climate Impact Lab, a consortium of 25 economists and policy experts from across the country, shows that the American South will be more affected byclimate change than any other region in the United States. The analysis also shows that the effects of climate change will transfer wealth from poor counties in the Midwest and Southeast to wealthier counties on the coasts and in the Northeast. This will aggravate the trend of economic inequality in the U.S.that already exists.
States that are alreadywarm or hot such as Florida, Arizona, Texas, and the states of the Deep South will therefore lose income potentialwhen jobs and other benefits migrate to cooler areas. Counties in states that border the Gulf of Mexico in particular are likely to experience the equivalent of a 20percent, county-level income tax solely attributable to climate change. This tax will come in the form of skyrocketing summer energy costs, struggling harvests, rising seas that engulf real estate, and heatwaves that trigger public health crises and inflate mortality rates.
TheU.S. GDP will decrease by around 1.2 percent for every additional degree Celsius of warming. Although the Paris Agreement terms would allow a rise of four degrees Celsius by the end of this century, but even if we didnt surpass that limit,the GDP of our country will still contract by 1.6 to 5.6 percent. If the Paris terms are not met, the damage will be more severe. (To put this into perspective, the biggest drop in GDP during the Great Recession was 6.3 percent in the fourth quarter of 2008. It took years to recover from the drop, and the ramifications were felt all over the world.)
The study is an exhaustive, detailed effort, which models every single day of weather in each county in the U.S. during the 21st century in order to simulate the economic costs of climate change. It is by far the most in-depth economic assessment of human-caused climate change to date. It is also highly significant because it takes a bottom-up approach, building on multiple microeconomic studies with regional economic data to provide a more detailed picture of the future of the U.S.
As detailed as the study is, the team omitted many serious risks of climate change because they lacked sufficiently detailed data to include them. For example, although the researchers could agree that biodiversity and other non-market goods are important, without a concrete way to assess the costs of those losses they didnt feel they could include them in the study. They also omitted increased chance of tail risks, which areunlikely yet catastrophic events likemass migration,violent civil or military conflicts, massive droughts, or major polar ice collapses.
The studys economic projections also end in 2099. While certain regions in the Northern regions of the U.S. might initially benefit from the pain the Southern statesare feeling thanks to climate change, that wont last. The authors of the study point out that the North will also experience more severe economic damages should climate change continue unchecked into the next century.
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Musk Says the Boring Company’s First Car Elevator Will Be Operating Next Week – Futurism
Posted: at 8:40 am
In Brief Elon Musk tweeted an update regarding the construction of The Boring Company's first tunnel under Los Angeles. The electric sled component of the elevator system is expected to be operational by next week. A Not So Boring Announcement
On Friday, Elon Musk posted a series of tweets that at first seemed a bit odd (I love floors), but that quicklyproved to be a lead-up for an exciting update about The Boring Company. Musks thread of tweets ended with a video that showcased one of the most intriguing parts ofThe Boring Companys forthcoming tunnel system: the elevator for the electric sled.
Musks concept for tunnels running under the streets of Los Angeles wont featureregular roads, so thats where the need forthiselectric sled comes in.According toThe Boring Companys websiteandthe concept video they released, the components of the elevator (shafts, sleds, and skates) will facilitatecarrying cars down into the tunnel, as well as ferrying people. The sled itself is capable of traveling at speeds of 200 k/h (125 mph).
According to Musk, the first elevator for the electric sled could be operational by as soon as next week. This would indicate thatconstruction of the first part of the L.A. tunnel the Culver City route which would connect to the LAX is well underway. With support from L.A. mayor Eric Garcetti, the progress isnt too surprising. That being said, just because some steady progress has been made and theres government support for Musks project, until the Hyperloop is fully realizedits unlikely that there will be an immediate use for the electric sleds elevator. Other than for the purpose of testing, of course.
Still, seeing the inner workings of the projects progress is pretty neat, as was emphasized by a short video Musk posted that shows the area around the tunnel site.
Indeed, this is exciting work, and Musk is again demonstrating that hes capable of turning his ideas no matter how far-fetched or relatively boring they may seem into a reality.
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