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Category Archives: Transhuman News

Could Astronauts Harvest Nutrients From Their Waste? – Smithsonian

Posted: August 25, 2017 at 3:42 am

Astronauts traveling to Mars may be able to pack a little lighter with microbes that could make nutrients and the building blocks of plastic.

smithsonian.com August 24, 2017 12:53PM

There's no doubt that the journey to Mars will be a feat of both engineering and logistics. But a few basic human waste products could actually help in the venture, providingnot onlyvital nutrients, but also materials that could be used to make tools.

In a presentationgiven this week at the American Chemical Society's National Meeting and Exposition, a scientist from Clemson University explained how genetically engineered yeast could feed on the astronaut's urine and carbon dioxide to produce valuable byproducts like omega-3 fatty acids and compounds commonly found in plastics, reports Andrew deGrandpre for the Washington Post.

"If astronauts are going to make journeys that span several years, well need to find a way to reuse and recycle everything they bring with them, biomolecular engineer Mark Blenner saidin a statement before his presentation. Atom economy will become really important.

This is an urgent problem. NASA is hoping to start human settlementson Mars in the next 20 years, and private space companies are pushing for even fastercolonization. But this will be no easy feat. Mars is just over 30 million miles from Earth, and the people that eventually make the tripmust be protected and nourishedthroughout the journey.

Every supply brought on board adds to the total mass of the craft flung into space. Not to mention each extra tool takes up space in what will likely already be a cramped environment. But without adequate provisions and tools, astronauts on boardthe Mars-bound craft would be doomed before they even left Earth.

To help get around this problem, NASA has been funding Blenner since 2015 to scrutinize a strain of yeast called Yarrowia lipolytica, reports Catherine Caruso for STAT. Blenner has used the yeast strain, a close relative of baker's yeast available in grocery stores, as a template that he then modifieswith genes from algae and phytoplankton. These alterations allow the microbes to produce the omega-3 fatty acids necessary for healthy metabolism in humans.

This yeast can also be genetically engineered to produce monomers, the basic building blocks of polymers that could be used by 3D printers to create new tools on the spacecraft or on Mars, reports Becky Ferreira of Motherboard.

But the yeast still need fuel to produce these products. That's where the astronauts, and their waste, comein. The microbes can use thenitrogen in humanurine andcarbon dioxide from their breath to create useful compounds.

This work is still in its very early stages, notes Nicola Davis of the Guardian.Blenner still needsto tweak the yeast so that it produces useful quantities of the nutrients and monomers. There's also the question of whether the microbes could survive in the low-gravity, high-radiation conditions of a trip to Mars.

If it all works out, however, future settlers on the Red Planet might not have to live solely off potatoes.

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Elon Musk shares first photo of SpaceX’s sleek new spacesuit – Florida Today

Posted: at 3:41 am

SpaceX's highly anticipated foray into spacesuits that will be worn by astronauts en route to the International Space Station has finally arrived. Wochit

The first image of SpaceX's new spacesuit, released by CEO Elon Musk on Wednesday, shows the company's foray into the hardware, which will be worn by astronauts traveling to the International Space Station.(Photo: Elon Musk / SpaceX via Instagram)

SpaceX's highly anticipated foray into spacesuits that will be worn by astronauts en route to the International Space Station and possibly beyond has finally arrived.

CEO Elon Musk took to Instagram early Wednesday morning to release the first teaser image of the company's futuristicspacesuits, which appear tofeature a mostly white palette that sharply contrasts with gray segments and accents.

Musk said it was "incredibly hard"to balance function and aesthetics for the hardwarethat will fulfill one of SpaceX's core obligations to NASA's Commercial Crew Program.

"Worth noting that this actually works (not a mockup)," Musk, also CEO of energy company Tesla, said."Already tested to double vacuum pressure."

[NOAA satellite launched from Space Coast captures incredible eclipse video]

[Reminder: NASA sonic boom testing begins near Kennedy Space Center]

More photos and detailsare expected over the next few days.

If timelines hold, SpaceX could launch astronauts on a Falcon 9 rocket from Cape Canaveral as soon as 2018, marking the first time humans have launched from U.S. soil since the final flight of space shuttle Atlantis in July 2011.

SpaceX could also use the spacesuits or at least portions of them for trips around the moon and, eventually, the company's ultimate goal of Mars colonization.

SpaceX was selected by NASA as a commercial crew partner under a $2.6 billion contract and has successfully delivered supplies and science experiments to the station under the separate Commercial Resupply Services program 11 times.

Aerospace giant Boeing, also contracted for the Commercial Crew Program at $4.2 billion, announced its version of a spacesuit earlier this year. Named Starliner, the modern suits feature plenty of blue, sneaker-like boots and Velcro.

Boeing could also launch astronauts to the ISS on an Atlas V rocket from Cape Canaveral as soon as 2018.

Contact Emre Kelly at aekelly@floridatoday.com or 321-242-3715. Follow him on Twitter and Facebook at @EmreKelly.

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The Drive for Perfect Children Gets a Little Scary – Bloomberg

Posted: at 3:41 am

Theres a lot of innovation going on in China these days, but perhaps not all of it is good. Chinese fertility centers are going well beyond American practices, using genetic diagnosis to influence how children conceived through in vitro fertilization will turn out. On one hand, the potential for improving human health is enormous. On the other hand, I am uneasy at the prospect of the power this gives parents. I dont trust people to take so much control over the future of human nature.

Sometimes you hear it argued that the complex nature of genes will prevent major feats of genetic engineering. That may be selling short future advances in Big Data and biomedicine, but even minor changes in genetic diagnosis and selection could have significant effects. Maybe you cant choose to have a child who will be happy, but you might be able to lower the chance of your kid having depression or social anxiety by some small amount. Over the course of generations, that will exert great influence over the nature of the human experience.

QuickTake Gene Editing

One risk, of course, is that parents will opt for some apparently desirable qualities in their children, and then the experiment will backfire, due to unforeseen genetic connections. Maybe well get happier kids, but they will be less creative, or less driven, or they might care less about others. Those are valid concerns, especially in these early days of genetic engineering. But I have a deeper worry, namely that things can go badly even when parents get exactly what they want.

If you could directly alter your kids genetic profile, what would you want? Its hard to know how the social debate would turn out after years of back and forth, but I was dismayed to read one recent research paper by psychologists Rachel M. Latham and Sophie von Stumm. The descriptive title of that work, based on survey evidence, is Mothers want extraversion over conscientiousness or intelligence for their children. Upon reflection, maybe that isnt so surprising, because parents presumably want children who are fun to spend time with.

Would a more extroverted human race be desirable, all things considered? I genuinely dont know, but at the very least I am concerned. The current mix of human personalities and institutions is a delicate balance which, for all of its flaws, has allowed society to survive and progress. Im not looking to make a big roll of the dice on this one.

Its also not difficult to imagine parents wanting children who are relatively well-behaved. The same research paper found that mothers, after extroversion, preferred the trait of agreeableness in their children, again over both intelligence and conscientiousness.

I was struck by a recent Chinese report that some parents are asking for children who are able to drink socially, for business purposes, and thus trying to avoid some genes that make it difficult to process alcohol. Caveat emptor.

Another risk is that parents may be too risk-averse. Especially if a family has only one or two kids, there may be a strong tendency to try to play it safe in terms of personality traits and cognitive abilities. Yet a greater diversity of human types may serve the greater good and perhaps offer intrinsic value too, by making the world an aesthetically richer and more diverse place. Unfortunately, its not hard to imagine a world where many parents opt against prospective children labeled, if only statistically, as too nerdy, too temperamental or too hard-working.

Parents choices, and their eventual public unveiling, may have harmful effects on social norms. What if it becomes known that a high percentage of parents opted for children with paler skin or straighter hair or a greater chance of being heterosexual? That knowledge could boost stigmas and social divisions, even with stringent anti-discrimination legislation. The parental choices could end up being seen as, in essence, the final court of public opinion.

We might expect that the regulators will say no to the most dangerous applications of genetic engineering, but can we be so sure? The techniques will be available in many different countries, and over time the more lax standards will have greater influence, if only through genetic engineering tourism. Parents are also a potent voting bloc, and if they really desire such choices, they may end up getting their way.

In China, these techniques are already about one-third as cheap as in the U.S., interest in them is growing rapidly, and there is talk of having them covered by national health insurance programs.

There is plenty of justified worry about greater discrimination these days, but were hardly talking about the biggest threats.

This column does not necessarily reflect the opinion of the editorial board or Bloomberg LP and its owners.

To contact the author of this story: Tyler Cowen at tcowen2@bloomberg.net

To contact the editor responsible for this story: Stacey Shick at sshick@bloomberg.net

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Forget me not – Triad City Beat

Posted: at 3:41 am

The community room looks like the interior of any well-appointed modern house from Starmount to Summerfield, with ocean-blue walls, mahogany-style tables matched with high-backed chairs, a sleek metallic refrigerator and comfortable couches.

Theres one key difference: The dining room, kitchen, living area and bathroom are collapsed into one large room with no dividers. Located on the third floor of a repurposed textile building across the street from Revolution Mill, the community room at the Center for Outreach in Alzheimers, Age and Community Health, or COAACH, functions as a classroom for families learning how to take care of a loved one developing Alzheimers disease or dementia.

The team wanted it to look like a home, said Donna Bradby, a publicist at NC A&T University, so you could cook a healthy meal, sit your loved one down at the table and then do things like transferring them to the bathroom and helping them brush their teeth.

Bradby gestured toward the full-length mirror at the end of the room.

My aunt, Annie Ruth Ingram, had Alzheimers, Bradby said. We stood in front of that mirror. She said, Who is that lady? I said, Oh, Aunt Annie Ruth. Thats you!

Annie Ruths husband, Charlie, passed away before she did, and its not uncommon for spouses to precede loved ones with Alzheimers in death. Caring for someone suffering from the disease, which progressively robs people of memory, cognition, muscle movement and personality, can take a heavy toll. Caregivers experience high levels of stress and cope with depression, often neglecting their own health and missing doctors appointments.

Those who take care of people with Alzheimers and other forms of dementia are twice as likely to report substantial emotional, financial and physical difficulties as other caregivers, according to the Alzheimers Association. Two thirds are women, and 34 percent are age 65 or older. A quarter of caregivers are considered a sandwich generation, meaning that theyre also taking care of a child under the age of 18.

Research has shown that Alzheimers is twice as likely to affect African Americans (and 1.5 times more likely to affect Hispanics) than non-Hispanic whites, but until about 10 years ago there was little research into why the disease strikes African Americans with such ferocity.

The answer is gradually coming into focus, thanks in part to the research of Dr. Goldie Byrd, the founding director of COAACH, which opened in 2014. A recent article by journalist and novelist Marita Golden in the Washington Post described the Greensboro center as a kind of ground zero for innovative, cross-disciplinary and community-based responses to the disease.

A complex interplay of environmental and genetic factors accounts for why Alzheimers inflicts a disparate toll on African Americans. An understanding of the interplay can help people make lifestyle choices that reduce the risk of the diseases onset, and researchers hope that understanding genetic factors will lead to the development of drugs to treat it. Alzheimers medications currently only address symptoms, without preventing, curing or slowing the disease.

On the environmental side of the equation, a series of studies presented at the 2017 Alzheimers Association International Conference in London in July added to a growing body of evidence that racial inequities increase the risk of Alzheimers and other dementias. Researchers at the University of Wisconsin found that African Americans were 60 percent more likely than whites to experience a stressful life event such as losing a job, the death of a child, combat, or growing up with a parent who abused drugs, which correlated with deterioration in cognition later in life. Other studies presented at the conference found that people born in states with high infant mortality rates a proxy for harsh early-life conditions and neighborhoods disadvantaged by poverty, poor housing and limited educational and employment opportunities were more likely to experience poorer cognitive function and dementia late in life.

Despite the diseases disparate impact, the science of how Alzheimers affects African Americans was woefully behind as recently as 15 years ago. Byrd joined the faculty at NC A&T as chair of the biology department in 2003, and that year she completed a sabbatical at the Duke Center for Human Genetics, where she helped initiate a study on Alzheimers. At the time, the university had 7,000 blood samples, but less than 50 were drawn from African-American volunteers.

We wanted to increase our knowledge about Alzheimers, particularly underrepresented groups like African Americans and Hispanics, Byrd said. These groups had a disproportionate burden, but there was so little in the literature about Alzheimers in these groups, particularly Alzheimers relationship to genetics.

As Byrd continued her research at her new post at A&T, the first challenge was to figure out how to overcome reluctance among African Americans to participating in studies.

We began by going into the community and asking different stakeholders lay people, the faith-based communities; we went to health fairs and barbershops and we asked people if they would participate in a study, Byrd recalled. What would the barriers be? What would the motivations be?

Distrust among African Americans due to the legacy of atrocities like the Tuskegee experiment a project launched by the US Public Health Service in 1932 in which researchers studied black men with syphilis without their informed consent and without treating them for the disease was an obvious hurdle. And while there are continuing reasons for African Americans and other underrepresented groups to distrust the medical establishment, Byrd emphasized that ethical research coupled with culturally calibrated outreach can overcome barriers.

People struggle with lack of access and the indifference when theyre treated even in 2017, Byrd said. They notice when they go to the doctor and they dont see people who look like them in 2017. There are recent studies that show that people of color dont get the same level of care.

African Americans will participate in studies, she added. Stereotypically, people think African Americans wont participate because of these atrocities. There are very good reasons for there to be hesitation and concern. We have to take the time to communicate with them to make sure they feel comfortable. We cant assume people who are mistreated are going to be at the front of the line unless we as researchers assure them that theyre safe, that were going to handle them and their specimens in an honest and respectful way, and we reassure them they can stop at any time.

The family-support component that became a core pillar of the COAACH center emerged as natural extension of Dr. Byrds understanding that she needed to design a study that would earn the trust of African-American volunteers.

The person I was working with we agreed we would create an environment that specifically targeted African Americans and engaged them directly in what the study was, that would create learning opportunities for this community, that would keep them engaged and keep them in the loop around whats happening with the research, Byrd said.

Although COAACH opened in response to a need to engage African Americans in Alzheimers research, Byrd and other staff members emphasize that the programs at the center are open to people of all races.

We created our COAACH center to assure not only African Americans but people of all races that we were there, and we werent going to get them into the study and leave, Byrd said. If people needed information about diabetes, which is linked to Alzheimers, they could call. If a church was having a health fair, they could call. We created a support group that people can attend; they dont have to be African American. They can attend Lunch & Learn.

Through Dr. Byrds efforts, the bank of data on African Americans with Alzheimers has dramatically expanded. As part of the Alzheimers Disease Genetics Consortium, which includes several other institutions, Byrd was part of a study that dramatically expanded the number of DNA specimens under review. In 2013, the consortium discovered that a variation in the ABCA7 gene that had previously been linked to Alzheimers was found to have a stronger link in African Americans than non-Hispanic whites.

Finding a gene link like ABCA7 gives researchers clues about what causes Alzheimers because variants might cause it to dysfunction and affect different populations in different ways.

In the hope of learning more about how genetics factors into the disease, COAACH is recruiting families with more than one member who has Alzheimers for an ongoing study. The center has collected samples from people in North Carolina, along with Virginia and New York.

There may be other genes like ABCA7 that are associated with the disease, Byrd said. There may be [treatments] that are specific to one population and not to another. Thats important because if we only did research in one population everything ends up being generalized. Our hope is there will be therapies and interventions that are specific to populations and not generalized. The advantage of doing studies is that well be much more inclusive and everyone will benefit.

There are many studies and clinical trials going on right now, she continued. We dont have any cure right now. We dont have anything to slow the disease. There are drugs that can assist with the symptoms. We are very hopeful that the pharmaceutical companies working with research institutions will come up a drug that can halt or slow the disease.

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Have Natalee Holloway’s Remains Finally Been Found? DNA Results Promising, Says Report – Hollywood Life

Posted: at 3:40 am

After twelve years, have we finally found out what happened to Natalee Holloway? Early DNA tests on the human remains discovered in Aruba indicate they might belong to the missing teenager!

Its been more than a decade since Natalee Holloway went missing in Aruba, as the Alabama native vanished on May 30, 2005. Now, 12 years later, her family might finally have some closure. Human remains discovered at a burial site in Aruba reportedly belong to a young woman of eastern European descent, according to DailyMail. Early DNA tests on these bones seem to match the remains to Natalee, as her family is of eastern European heritage. Further DNA testing is needed to confirm these initial findings, but it appears that this discovery is the breakthrough the Holloways have been hoping for.

The full DNA testing results which will determine if the bone fragments belong the missing 18-year-old girl are expected within two weeks, a source close to the case tells DailyMail. The nature of these remains means further testing is required before anything can be confirmed, the source added. The discovery is part of The Disappearance of Natalee Holloway, a docuseries featuring her father, Dave Holloway, and private investigator TJ Ward searching for answers. Natalees mother, Beth Holloway, has also assisted in the search, as she reportedly provided a saliva sample to help out in the remains DNA testing.

Experts are reportedly conducting a mitochondrial DNA test (mtDNA test) on the remains at a reputable, undisclosed lab in the US, the source tells DailyMail. These tests race a persons matrilineal or mother-sideancestry using DNA. This DNA is unchanged when passed down by the mother to all her children. If the mtDNA inside the fragments match the mtDNA in Beths saliva, itll be conclusive evidence that these remains belong to Natalee.

Natalees father made the announcement that he and TJ had discovered the remains after an 18-month undercover investigation on the Aug. 16 episode of the Today show. An individual who had personal knowledge from Joran van der Sloot, 30, the prime suspect in Natalees disappearance, led them to the remains. However, the Aruban authorities are calling Daves claim into question. During an investigation by police in an area indicated by Mr. Holloway, we found remains, but they were found to be from animals, Aruba Public Prosecutor Dorean Kardol told the Huffington Post.

Plus, the FBI says they dont have records of human remains being brought into the U.S. from Aruba in connection with the Holloway case. On top of that, if these remains did belong to Natalee, they would be useless when coming to prosecuting the killer. Tampering with the evidence aka removing them for testing violates the chain of custody. If we wanted to take the case to court, Dorean Kardol said, we would be in trouble because we could not use that evidence.

What do you think, HollywoodLifers? Do you think they might have found Natalees remains?

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Researchers encoded a film clip in DNA and store it inside a living … – Boing Boing

Posted: at 3:40 am

In an astonishing step forward in biomolecular computing, Harvard researchers encoded a 19th century film clip in DNA and stored it inside living bacteria. Later, they sequenced the bacterium's genome and decoded the film. From IEEE Spectrum:

To get a movie into E. colis DNA, (neuroscientist Seth) Shipman and his colleagues had to disguise it. They converted the movies pixels into DNAs four-letter codemolecules represented by the letters A,T,G and Cand synthesized that DNA. But instead of generating one long strand of code, they arranged it, along with other genetic elements, into short segments that looked like fragments of viral DNA.

E. coli is naturally programmed by its own DNA to grab errant pieces of viral DNA and store them in its own genomea way of keeping a chronological record of invaders. So when the researchers introduced the pieces of movie-turned-synthetic DNAdisguised as viral DNAE. colis molecular machinery grabbed them and filed them away.

The Gartner Hype Cycle places emerging technologies on a rising-falling-rising curve.

Tony Fadell is best known one of the fathers of the iPod at Apple, and as the former CEO of Nest. Weve agreed to forget that he led the Google Glass division for a while, too. Today, news broke that the serial inventor and investor is now working with companies including Samsung Electronics and Foxconns []

The Wall Street Journal is reporting that millennials have learned how to get free TV with a simple antenna, for a one-time cost of about $20. Us old-schoolers have known of this ancient wisdom since, well, forever but have neglected to pass down to the younguns. But the crazy thing is that its not just []

Top-performing content doesnt come from pure inspiration. So how do you get the maximum number of eyeballs to see your marketing copy? By analyzing the impact of the keywords within. Serpstat does this all for you. It can monitor up to 200 keywords in your projects, across 10 total domains. They keep track of the []

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New DNA evidence links Warren Forrest to 2 killings – The Columbian

Posted: at 3:40 am

A A

Clark County detectives say that new DNA evidence helps link suspected serial killer Warren Forrest to two more victims, a huge break in some of the agencys oldest unsolved murders.

Blood on a weapon used as evidence in a 1974 case against Forrest was recently determined to belong to a different victim: Martha Morrison, a 17-year-old Portland girl whose body was found in rural Dole Valley more than 40 years ago.

Morrisons body was found 120 feet from that of Carol Valenzuela, 18. Based on the proximity in time of the killings and location of the bodies, Hoss said that Forrest can also be linked to Valenzuelas death.

Up until now, nothing was physically linking him to either of those disappearances, or those bodies, Clark County Sheriffs Office Sgt. Duncan Hoss said. Its a big deal.

Forrest, 68, of Battle Ground is suspected of having at least six victims, but hes only been convicted of one murder. He is serving a life sentence at the Washington Department of Corrections Monroe Correctional Complex for the 1974 murder of 19-year-old Krista Blake of Vancouver.

Periodically, he goes before a sentencing review board, where his release is considered. The new evidence could seal his fate and keep him behind bars for the rest of his life.

Blake went missing on July 11, 1974, when she was last seen getting into a blue Ford van, but her remains werent found until two years later.

During those two years, Forrest went to trial for a similar crime, one that had a different outcome.

On Oct. 1, 1974, a 20-year-old Camas woman got into a van driven by Forrest, where she was threatened with a knife and bound with tape.

Forrest drove her to Lacamas Lake Park, where he raped her, shot her with an air pistol, choked her and stabbed her five times in the chest. The woman survived the attack and made her way to a public road for help.

She later identified Forrest as the man responsible and he was arrested on rape, assault and robbery charges.

In that case, Forrest was acquitted of the charges by reason of insanity, meaning the crimes were committed when Forrest was insane, and he was committed to Western State Hospital.

In 1976, Blakes body was found and Forrest was tied to her death. After a trial, he was convicted of murder and sentenced to life in prison in 1979.

For decades, detectives suspected that Forrest was tied to homicides and disappearances of several other young women in the early 70s.

Investigators believe that Forrest is responsible for at least six other deaths and that Jamie Grisim, who disappeared in 1971 on her way home from school at 16, was his first victim.

Forrests name also comes up in connection with Barbara Ann Derry, whose body was found in 1972 and Gloria Knutson, who went missing in 1974.

Also in 1974, hunters found skeletal remains of two women in shallow graves in the Dole Valley area. One was identified as Carol Valenzuela, and the other remained unidentified for 40 years, then in 2015 was identified as Morrison.

In June 2014, the Clark County Sheriffs Office had more than a dozen open homicide investigations that dated to 1962. Major crimes detectives are often busy with the deluge of incoming cases, so then-Sheriff Garry Lucas formed a cold case unit of volunteer investigators to breathe new life into the stale investigations.

Among those volunteers was former prosecutor Denny Hunter who prosecuted the murder cases against Forrest.

When he and the other investigators sat down to asses the cases, Hunter remembered the bloodied air pistol Forrest used in the rape and assault case.

Everyone assumed the blood stain on the air pistol belonged to the original victim, Hoss said. One of the cold case detectives, instead of assuming, actually verified.

So the pistol, which had been in a secure holding area for 40-plus years, was sent to the state crime lab.

The results came back to a profile for a female Caucasian, but that profile didnt match any known DNA samples.

A year later, investigators got a break that would help them find their answer.

Nikki Costa, operations manager for the County Medical Examiners Office, took it upon herself to identify the unidentified remains found near those of Carol Valenzuela. It took her eight years, but in 2015, she was able to determine that the remains belonged to Martha Morrison.

Since then, the crime lab has connected the puzzle pieces and identified the blood found on Forrests gun as belonging to Morrison.

In this maze of events, establishing a DNA profile and identifying Martha, we turned a major corner in this case, Costa said.

The breakthrough has implications for not one, but two unsolved homicides.

Hoss said that since Morrisons body was found in such close proximity to that of Valenzuela, investigators can tie Forrest to her death too.

Detectives are still working on ironing out the details, though.

They hope to have a statement of probable cause, which outlines support for an arrest, to prosecutors in the next few weeks.

If prosecutors decide there is enough evidence for a charge, Hoss said that theyll apply for an arrest warrant and have Forrest transported to the Clark County Jail to face the charges.

Hoss said that when the cold case unit first formed, there werent high expectations for results. But the volunteer investigator worked doggedly to reinvestigate these cases, and the break, he said, is a nice payoff.

They have put all this time, energy and effort into it, and were hoping its going to finally result in a conviction and mean closure for the families, Hoss said.

We want to hold Warren accountable.

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Missouri governor stays execution of Marcellus Williams, says officials will probe DNA evidence in the case – Washington Post

Posted: at 3:40 am

Hours before convicted killer Marcellus Williams was scheduled to die by lethal injection, Missouri's governor has halted his execution. His attorneys argued that recent DNA evidence shows he is innocent in the killing of a former newspaper reporter. (Reuters)

Missouri Gov. Eric Greitens (R) on Tuesday stayed the scheduled execution ofMarcellus Williams, just hours before the death-row inmate was set to be put to death for the 1998 killing of a former newspaper reporter.

Williamss looming lethal injection prompted scrutiny and a last-ditch appeal to the U.S. Supreme Court from his attorneys, who pointed to new DNA evidence in arguing that Missouri may have been on the verge of executingthe wrong person.

Greitens said he would appoint a board to look into the new DNA evidence and other factors before issuing a report about whether or not Williams should be granted clemency.

A sentence of death is the ultimate, permanent punishment, Greitens said in a statement. To carry out the death penalty, the people of Missouri must have confidence in the judgment of guilt.

[Earlier this year, Arkansas executed four inmates in eight days]

Williams, 48, was convicted in 2001 of brutally killing Felicia Lisha Gayle, who had been a reporter with the St. Louis Post-Dispatch. Gayle was in her home when she was stabbed 43 times with a butcher knife, according to court records.

Williams was scheduled to be executed in 2015 for the high-profile killing, but the state Supreme Court stayed his lethal injection, allowing him time to obtain the new DNA testing.

Attorneys for Williams have arguedhe is innocent, pointing to DNA tests they say producedconclusive scientific evidence that another man committed this crime. They say this evidence shows that DNA belonging to someone else was found on the murder weapon, exonerating Williams.

Theyre never going to ever confront an actual innocence cause more persuading than this involving exonerating DNA evidence, said Kent Gipson, one of Williamss attorneys. Ive seen a lot of miscarriages of justice, but this one would take the cake.

State officials, though, said they still believed Williams is guilty because ofother compelling non-DNA evidence.

[Johnson & Johnson says its drug shouldnt be used in executions]

In court filings, the office of Joshua D. Hawley, Missouris attorney general, listed some of these other factors, describing two people a man who served time with Williams and Williamss girlfriend who both told police that he confessed to the killing. Williams had also sold a laptop stolen from Gayles home, Hawleys office wrote in the filings, and items belonging to Gayle were found in a car Williams drove the day she was killed.

Based on the other, non-DNA, evidence in this case, our office is confident in Marcellus Williams guilt and plans to move forward, Loree Anne Paradise, Hawleys deputy chief of staff, wrote in an email Tuesday.

After Williamss execution was stayed, Paradise said her office was still confident in what the jury determined in 2001.

We remain confident in the judgment of the jury and the many courts that have carefully reviewed Mr. Williams case over sixteen years, she wrote Tuesday afternoon. We applaud the work of the numerous law enforcement officers who have dedicated their time and effort to pursuing justice in this case.

Attorneys for Williams and state officials had both made their arguments to Supreme Court Justice Neil M. Gorsuch, who is assigned cases from the federal circuit covering Missouri. Neither Gorsuch nor the full court had publicly weighed in before Greitens halted the scheduled execution.

[Pfizer tightens restrictions to keep drugs from being used in executions]

Alittle more than four hours before Williams was set to be executed,Greitens signed an executive orderhalting the lethal injection. Greitens alsoappointed a board of inquiry to further consider Williamss clemency request and issue a report about whether he should be executed or have his sentence commuted.

In his statement,Greitens said he was appointing the board in light of new information.According to Greitenss executive order, the board will consider newly discovered DNA evidence as well as any other relevant evidence not available to the jury.

The controversy surrounding Williamss scheduled lethal injection had drawn unusual attention to what would be a relatively rare execution in the United States, where the death penalty has been declining for years.

There have been 16 people executed so far this year in the United States, one of them in Missouri, which is among a handful of states still regularly executing inmates. Last year, there were 20 executions in the United States, the fewest in 25 years. That number is expected to increase slightly this year, but 2017 will still see one of the lowest annual number of executions than most years since 1990.

[Why the U.S. could see more executions this year]

Death sentences have become less common nationwide, dropping from 315 such sentences in 1996 to 31 last year, according to the Death Penalty Information Center, a Washington-based group that tracks capital punishment. Public support for the death penalty has also fallen over the same period. In a Pew Research Center survey last year, American support for capital punishment fell below 50 percent for the first time since Richard Nixon was president. A Gallup poll, also conducted last year, found support remained at 60 percent. In both cases, the numbers represented a sharp drop from the mid-1990s, when 4 in 5 Americans backed the death penalty.

While some states have abandoned capital punishment or been unable to carry out executions amid an ongoing drug shortage, Missouri has been an outlier. Missouri is one of three states, along with Texas and Georgia, to execute at least one inmate each year since 2013.

In 2015, when Missouri last intended to execute Williams, the states Supreme Court stayed the lethal injection. A laboratory tested evidence from the scene of Gayles killing and a DNA expert determined that Williams could not have contributed to the DNA found on the knife that killed the former reporter, Williamss attorneys said.Last week, theMissouri Supreme Courtrejected a request to stay Williamss execution without explanation.

Missouri officials had argued in court that in order to exonerate Williams, DNA evidence would have to explain how Williams ended up with the victims property, and why two witnesses independently said he confessed to them, or at least provide a viable alternate suspect. They also said that just showing unknown DNA on the knife handle does not alone prove Williamss innocence.

The item was a kitchen knife with both male and female DNA on the handle, Hawleys office wrote in a filing to the Supreme Court. It is reasonable to assume people not involved in the murder handled the knife in the kitchen. And there is no reason to believe Williams would not have worn gloves during a burglary and murder, as he wore a jacket to conceal his bloody shirt after he left the murder scene.

[Ohio executes Ronald Phillips, resuming lethal injections after three-year break]

Gipson argued that the case against Williams was always weak, consisting primarily of the statements of two jailhouse informants who claimed Williams had confessed to the crime. Gipson also said that bloody footprints at the scene did not match Williamss shoe size and added that bloody fingerprints were never tested or compared to Williamss fingerprints because they were lost by police.

The DNA testing, which Williamss attorneys said was enabled by advances in technology, formed the main argument they made in appealing to the U.S. Supreme Court.

A DNA profile was developed from the handle of the knife that was found in the victims body and that does not match the DNA of Marcellus, Gipson said Tuesday, adding that three separate experts have concluded that the DNA left on the knife and at the scene was a match for another man and not Williams. Its clear that the DNA on the knife is the DNA of the killer. Each expert has concluded that you can scientifically exclude Marcellus as the contributor of the DNA on the knife.

Civil rights groups also weighed in on the case, both due to Williamss claims ofinnocence as well as racial undertones in the prosecution of a black man charged with killing a white woman.

The Supreme Court has emphasized over and over that because death is a unique punishment there is need for heightened reliability before its imposed, said Sam Spital, director of litigation for the NAACP Legal Defense Fund, which is not directly involved in Williamss case. One of the really significant questions raised by Mr. Williamss case is, what does it mean when you have issues of innocence?

Like Williamss attorneys, Spital noted the lack of forensic evidence linking Williams to the crime as well as the new DNA evidence. Spital also pointed to another concern, echoing attorneys for Williams, who described the case as racially charged. Spital said six of the seven potential black jurors in the case were struck from the jury pool in one case because the potential juror looked like Williams.

This execution has to be stayed so these substantial questions of innocence can be considered, in addition to some real concerns about race discrimination, Spital said before the governor had issued the stay.

This story has been updated since it was first published.

Read more:

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An Arkansas death row inmate took their fathers life. Heres why they dont want the killer executed.

Drug companies take aim at executions and demand their drugs back

Ohios youngest death row inmate never touched the murder weapon. Why was he sentenced to death?

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Missouri governor stays execution of Marcellus Williams, says officials will probe DNA evidence in the case - Washington Post

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Danish police: DNA from dismembered body matches missing journalist – CNN

Posted: at 3:40 am

At a press conference, chief investigator Jens Mller Jensen said police had linked the victim to the torso with DNA obtained from her toothbrush and hairbrush. Blood found on the submarine was also a match for Wall, he said.

Mller Jensen said the body had apparently been punctured to let the air out before sinking it, and it was weighted down in a presumed attempt to prevent it floating.

Wall, 30, had boarded a 17-meter, privately built submarine on August 10 for a story she was writing about its inventor, Peter Madsen.

She was last seen on that day in an image that allegedly showed her standing with Madsen in the tower of the submarine in Copenhagen Harbor.

A passing cyclist found the torso Monday afternoon on the southwest side of Amager island near the Danish capital.

Police had earlier said the body appeared to have been deliberately dismembered.

"Naturally, the DNA match is a relatively large breakthrough in the investigation which will now continue until we have built all possible information in the case," said Mller Jensen.

Investigators and divers are carrying out an extensive search Wednesday for "remaining body parts and clothing" in coastal areas of Amager island, he said.

In a statement posted to Facebook, Wall's mother, Ingrid Wall, spoke of the family's "immense grief and shock" on learning that the journalist's remains had been found, and said many questions remained unanswered.

She recalled the impact of her daughter's disappearance on her family, friends and colleagues around the world, as well as the powerful stories she had told from remote corners of the planet.

"Following Kim's disappearance, we have received countless messages about how loved and appreciated she was -- as a human being, as a friend and as a journalist. It's a true testament to the impact she's had on others," she said.

"She gave a voice to weak, vulnerable and marginalized people. It's a voice this world needed for years to come, but that has now been silenced."

Madsen, who has been charged with manslaughter, told a closed-door court hearing Monday that Wall had died in an accident and was buried at sea in an "unspecified place" in Kge Bay, according to a statement.

Madsen, 46, originally claimed he had dropped her off on land on the night of August 10, according to a police statement.

But police later said Madsen had provided them with a "different explanation."

The inventor was charged with manslaughter on August 11 and ordered to be held in custody for 24 days.

His lawyer Betina Hald Engmark told Denmark's TV2 at the time that her client "accepts the arrest but still denies the crime."

According to CNN's Swedish affiliate Expressen, the submarine -- which had sunk -- was found at 10:30 a.m. on Friday, August 11, 15 hours after it had departed Copenhagen.

Police said there was no trace of Wall when the submarine was found by emergency services.

Expressen reporter Federico Moreno, speaking to CNN from Amager island near where the torso was found, said the search effort appeared to have intensified since Tuesday.

He said he could see about 10 divers searching the waters off the island, more than double the number he'd seen a day earlier. The spot where the torso was found is also not far from the location where the submarine sank, he said.

Danes with whom Moreno has spoken about the case say the circumstances are very strange and that they have questions about Madsen's changing accounts of what happened, he said.

Moreno said that Madsen's lawyer, Hald Engmark, had sent him a text message after Wednesday's police press briefing to say that Madsen maintained his innocence.

Madsen was already famous in Denmark before his name hit the headlines in relation to this case, Moreno said. He had launched his submarine, the UC3 Nautilus, in 2008 with the help of crowdfunding.

Wall wasn't a household name in Sweden, in part because she mostly wrote for English-language publications, Moreno said, but she was an experienced reporter and her family is well known in media circles.

Wall, a graduate of Columbia University and London School of Economics, was based between Beijing and New York. Her work appeared in the New York Times, the Guardian and TIME among others.

Her father was a photojournalist for Expressen for many years and her brother also works as a photojournalist for Swedish publications, Moreno said.

CNN's James Masters, Jim Stenman, Sophia Chalmer, Hilary McGann and Henrik Pettersson contributed to this report.

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Danish police: DNA from dismembered body matches missing journalist - CNN

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Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion – Arizona Public Media

Posted: at 3:39 am

Over millions of years, the Arizona bark scorpion has evolved into a true desert survivor.

Now, new research traces its origins to an abrupt and massive genetic event.

More than 450 million years ago, the entire genetic instruction book of spiders' and scorpions' common ancestor doubled, according to a genomic comparison of the common house spider (Parasteatoda tepidariorum) and the Arizona bark scorpion (Centruroides sculpturatus).

Kim Worley of Baylor College of Medicine, who worked on the BMC Biology study, said gene replicas help species diverge by freeing up copies for other uses.

"One copy can continue to provide the functions that it was used for originally, and the new copy is not constrained to provide those functions because the original copy's already providing it," Worley said.

Whole genome duplication is not unheard of. Copies of single genes or chromosomes are more common.

"Genomes change over time, often because of this duplication and divergent process. And sometimes that's individual genes or parts of genes, and sometimes that's larger regions parts of chromosomes, or even whole chromosomes, or even whole genomes in some cases," Worley said.

Most duplicate genes are later lost; those that remain can take on new roles.

The gene sequencing took place as part of a pilot study for i5k, a project that aims to sequence 5,000 arthropod genomes.

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Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion - Arizona Public Media

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