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Mutation Responsible for Tumors Are Discovered in Concealed Sequences in the Cancer Genome – Science Times

Posted: January 22, 2020 at 6:44 pm

(Photo : upload.wikimedia.org)

The search for a cancer cure has led researchers in the OICR, to stumble on a ground-breaking discovery. Previously unknown and undetected in the sequences of non-coding DNA, which can transform into cancer-causing agents in the host cell. Prior to this discovery, this was largely unknown until now.

An investigation into the mutagenic gene demonstrated new ways that it can multiply and advance cancer further. Since it was practically hidden, then specialists are pointing their crosshairs on where to begin. More data uncovered will give more clues on how to tame cancer, later on, better tests to detect it and devise better-targeted therapy for patients.

What made this study more conclusive than those before it, that only covered 2% of the gene for producing proteins needed inside the cell. Furthermore, it dug deeper into more mutation probabilities that weren't explored until this is study. Going further into unknown territory into the non-coding parts of the human genetic matrix. Trying to figure out what causes the genes to get tripped and activated. Which triggers the formation of cancer-causing mutation wholesale inside the host cell.

The lead of the study, Dr. Jri Reimanda, and investigator at OICRsaid that mutation caused by altered proteins are not common in large coding regions. It is this far proximity that does not make it suspect at all. Analyzing data based on these will be challenging to analyze too.

Armed with improved statistical tools and more complete genomic information makes it more accurate. Data that was collected from 1,800 patients is the base of the genomic data, that produced evidence of molecularly based ways that led to cancer, and worse tumors too.

Researchers had a go at 100,000 sections of each patient, now paying more attention to the unexplored non-coded location on the sequence to interact with. One location in the genome is determined to control and anti-tumor gene in cancerous cells. It was located as far as, 250,000 base pairs away from the gene located in the three-dimensional genome. To gain an idea of how it worked more, they did gene editing and experiments in host human cells. To test how potent cancer is in this non-coded location in the genetic sequencing.

Throughout the process of investigating the region involved, several conclusions about the non-coding region that is involved in the development of cancer cells. So far, with more specialized algorithms and data about cancer genomes will lead to analysis and cures. Just one of the findings that lead to a better cure for patients, or detecting it before it gets worse.

All the data gained from "Reimand's" study is free and for use by other scientists studying cancer. Everything from the statistical algorithms to overall methods is tried and tested for accuracy. Anyone has free access to add more to this relevant research.

It cannot be stressed enough that genes are grossly affected by non-coding gene sequences, with easy turning on or off. When a mutation happens, it will cause abnormal functions inside the cell to become cancerous. Another fellow, Helen Zhu a student and author as well, mentioned the method called "ActiveDriverWGS" zeroes in on cancer in the genome.

Finding the mutations that drive development to cancer is the key to track what causes it. Finding and digging up more about it should help in developing medicines to suppress it. This will give rise to better analyses and cures for patients that should be a good development for everyone.

Read: New tumor-driving mutations discovered in the under-explored regions of the cancer genome

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Mutation Responsible for Tumors Are Discovered in Concealed Sequences in the Cancer Genome - Science Times

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LifeOmic Partners with Indiana University-based Healthy Breast Tissue Bank to Advance Breast Cancer Research – P&T Community

Posted: at 6:44 pm

INDIANAPOLIS, Jan. 22, 2020 /PRNewswire/ --LifeOmic, the creator of the LIFE mobile apps and the Precision Health Cloud (PHC) platform in use at major medical and cancer centers, today announced a partnership with the Susan G. Komen Tissue Bank, a unique resource established by researchers at Indiana University Melvin and Bren Simon Cancer Center and Indiana University School of Medicine, to improve breast cancer research. The Komen Tissue Bank at the IU Simon Cancer Center will utilize the PHC for genomic, clinical and imaging data aggregation and analysis, as well as its health care compliant survey capabilities.

The Komen Tissue Bank is the only repository in the world for normal breast tissue and matched serum, plasma and DNA. The tissue bank advances breast cancer research by offering high quality, richly annotated tissue samples to scientists worldwide. Scientists who access the Komen Tissue Bank's Virtual Tissue Bank can query the medical history of donors, request tissue and download existing data. The current system does not support genomic data.

"We are passionate about sharing our research resources with scientists worldwide," said Jill Henry, chief operating officer of the Komen Tissue Bank at the IU Simon Cancer Center. "Using LifeOmic's PHC will expand the Virtual Tissue Bank'scapabilities to help fuel ongoing treatment and prevention discovery."

LifeOmic and the Komen Tissue Bank will work together to deploy the Virtual Tissue Bank onto the PHC's secure, reliable and scalable platform. The new platform enables researchers around the world to query an extended data model including whole-genome sequencing data. The use of analytics tools in the PHC allows researchers to overlay data reported from participants' clinical history with all other data available in the PHC, including genomic, clinical and imaging data.

"The Precision Health Cloud was created to break down silos that exist between current systems, to help advance precision health," said Dr. Don Brown, CEO and founder of LifeOmic. "We are thrilled to partner with the Komen Tissue Bank because of our shared goal to break down silos and help its mission to end breast cancer by enabling advanced research using PHC."

For more information on LifeOmic's PHC, visit: https://lifeomic.com/products/precision-health-cloud/.

About LifeOmic:

LifeOmic is the software company that leverages the cloud, machine learning and mobile devices to power precision health solutions for providers, researchers, health care IT, pharma and individuals. The company's cloud-based software securely aggregates, stores and analyzes patient data to accelerate the development and delivery of precision health treatments. LifeOmic's core competency is the Precision Health Cloud, a cloud-based repository of all patient data such as a basic profile, whole genome sequences, gene expression levels, lab results, medical images and more. The company's product lines also include security software platform JupiterOne and consumer-centric LIFE mobile apps.

Founded in 2016 and headquartered in Indianapolis, LifeOmic was created by serial entrepreneur Don Brown and boasts a team of highly experienced engineers, scientists and security specialists.

For more information, visit https://lifeomic.com.

About The Komen Tissue Bank at the IU Simon Cancer Center:

The Susan G. Komen Tissue Bank, a resource established by researchers at Indiana University Melvin and Bren Simon Cancer Center and Indiana University School of Medicine in Indianapolis, is uniquely positioned to characterize the molecular and genetic basis of normal breast development and compare it to the different types of breast cancer. The bank was established expressly for the acquisition of normal tissues from volunteer donors with no clinical evidence of breast disease and/or malignancy, providing a resource to investigators around the globe. More than 6,000 women have donated breast tissue since 2007. In all, more than 12,000 women also have donated DNA and blood to the tissue bank.

For more information, visit https://komentissuebank.iu.edu/

Contact:

Katie GrantBAM Communications(858) 284-7768katieg@bamcommunications.biz

Michael SchugIndiana University Melvin and Bren Simon Cancer Center(317) 278-0953maschug@iu.edu

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Hackensack Meridian Health Center for Discovery and Innovation to Host Genomic Medicine Symposium – The Trentonian

Posted: at 6:44 pm

NUTLEY, N.J., Jan. 17, 2020 /PRNewswire/ --Genomic medicine's groundbreaking treatments, and its future promise, will be the focus of a full-day symposium at the Hackensack Meridian Health Center for Discovery and Innovation (CDI) on Wednesday, February 19.

This emerging discipline for tailoring active clinical care and disease prevention to individual patients will be the focus of presentations given by eight experts from medical centers in the U.S.A. and Canada.

"The Genomic Medicine Symposium convenes a diverse group of scientific experts who help serve as a vanguard for precision medicine," said David Perlin, Ph.D., chief scientific officer and vice president of the CDI. "At the Center for Discovery and Innovation, we are working to make genomics a central component of clinical care, and we are delighted to host our peers and partners from other institutions."

"The event is one-of-a-kind," said Benjamin Tycko, M.D., Ph.D., a member of the CDI working in this area, and one of the hosts. "We are bringing together great minds with the hope it will help inform our planning for genomic medicine within Hackensack Meridian Health and inspire further clinical and scientific breakthroughs."

Cancer treatments, neuropsychiatric and behavioral disorders, cardiometabolic conditions, autoimmune disease, infectious disease, and a wide array of pediatric conditions are areas where DNA-based strategies of this type are already employed, and new ones are being tested and refined continually.

The speakers come from diverse medical institutions and will talk about a variety of clinical disorders in which prevention, screening, and treatment can be informed through genomic and epigenomic data.

Among the speakers are: Daniel Auclair, Ph.D., the scientific vice president of the Multiple Myeloma Research Foundation; Joel Gelernter, M.D., Ph.D., Foundations Fund Professor of Psychiatry and Professor of Genetics and of Neuroscience and Director, Division of Human Genetics (Psychiatry) at Yale University; James Knowles, M.D., Ph.D., professor and chair of Cell Biology at SUNY Downstate Medical Center in Brooklyn; Tom Maniatis, Ph.D., the Isidore S. Edelman Professor of Biochemistry and Molecular Biophysics, director of the Columbia Precision Medicine Initiative, and the chief executive officer of the New York Genome Center; Bekim Sadikovic, Ph.D., associate professor and head of the Molecular Diagnostic Division of Pathology and Laboratory Medicine at Western University in Ontario; Helio Pedro, M.D., the section chief of the Center for Genetic and Genomic Medicine at Hackensack University Medical Center; Kevin White, Ph.D., the chief scientific officer of Chicago-based TEMPUS Genetics; and Jean-Pierre Issa, M.D., Ph.D., chief executive officer of the Coriell Research Institute.

The event is complimentary, but registration is required. It will be held from 8 a.m. to 4:30 p.m. at the auditorium of the CDI, located at 111 Ideation Way, Nutley, N.J.

The event counts for continuing medical education (CME) credits, since Hackensack University Medical Center is accredited by the Medical Society of New Jersey to provide continuing medical education for physicians.

Hackensack University Medical Center additionally designates this live activity for a maximum of 7 AMA PRA Category 1 Credit TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For more information, visit https://www.hackensackmeridianhealth.org/CDIsymposium.

ABOUTHACKENSACKMERIDIAN HEALTH

Hackensack Meridian Health is a leading not-for-profit health care organization that is the largest, most comprehensive and truly integrated health care network in New Jersey, offering a complete range of medical services, innovative research and life-enhancing care.

Hackensack Meridian Health comprises 17 hospitals from Bergen to Ocean counties, which includes three academic medical centers Hackensack University Medical Center in Hackensack, Jersey Shore University Medical Center in Neptune, JFK Medical Center in Edison; two children's hospitals - Joseph M. Sanzari Children's Hospital in Hackensack, K. Hovnanian Children's Hospital in Neptune; nine community hospitals Bayshore Medical Center in Holmdel, Mountainside Medical Center in Montclair, Ocean Medical Center in Brick, Palisades Medical Center in North Bergen, Pascack Valley Medical Center in Westwood, Raritan Bay Medical Center in Old Bridge, Raritan Bay Medical Center in Perth Amboy, Riverview Medical Center in Red Bank, and Southern Ocean Medical Center in Manahawkin; a behavioral health hospital Carrier Clinic in Belle Mead; and two rehabilitation hospitals - JFK Johnson Rehabilitation Institute in Edison and Shore Rehabilitation Institute in Brick.

Additionally, the network has more than 500 patient care locations throughout the state which include ambulatory care centers, surgery centers, home health services, long-term care and assisted living communities, ambulance services, lifesaving air medical transportation, fitness and wellness centers, rehabilitation centers, urgent care centers and physician practice locations. Hackensack Meridian Health has more than 34,100 team members, and 6,500 physicians and is a distinguished leader in health care philanthropy, committed to the health and well-being of the communities it serves.

The network's notable distinctions include having four hospitals among the top 10 in New Jersey by U.S. News and World Report. Other honors include consistently achieving Magnet recognition for nursing excellence from the American Nurses Credentialing Center and being named to Becker's Healthcare's "150 Top Places to Work in Healthcare/2019" list.

The Hackensack Meridian School of Medicine at Seton Hall University, the first private medical school in New Jersey in more than 50 years, welcomed its first class of students in 2018 to its On3 campus in Nutley and Clifton. Additionally, the network partnered with Memorial Sloan Kettering Cancer Center to find more cures for cancer faster while ensuring that patients have access to the highest quality, most individualized cancer care when and where they need it.

Hackensack Meridian Health is a member of AllSpire Health Partners, an interstate consortium of leading health systems, to focus on the sharing of best practices in clinical care and achieving efficiencies.

For additional information, please visit http://www.HackensackMeridianHealth.org.

About the Center for Discovery and Innovation:

The Center for Discovery and Innovation, a newly established member of Hackensack Meridian Health, seeks to translate current innovations in science to improve clinical outcomes for patients with cancer, infectious diseases and other life-threatening and disabling conditions. The CDI, housed in a fully renovated state-of-the-art facility, offers world-class researchers a support infrastructure and culture of discovery that promotes science innovation and rapid translation to the clinic.

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SpaceX has ambitions to carry a million people to Mars by 2050, tweets Musk – Technowize

Posted: January 20, 2020 at 5:50 am

In a series of Tweets recently, Elon Musk said that SpaceX plans to ferry 100k people to Mars by 2050 on its Starship and Super Heavy Rocket system, which is designed to service all Earth orbit needs as well as the Moon and Mars.He tweeted that a 100 Starships were needed a year to send about a 100k people to Mars whenever the two planets orbits are aligned.

This happens every 26 months when the distance between the Earth and Mars decreases. Musks ambition is to send a 1000 Starships into orbit during this short window of about a month, and transport people to Mars taking advantage of the decreased commuting time.Travellers would still be looking at months of travel aboard the Starship transporter before reaching their destination. When questioned on the validity of the numbers by a follower, Elon Musk agreed that the Starship could be carrying about a million people to Mars from Earth by 2050.Musk further elaborated on the mechanics of this ambitious plan. He tweeted that a crazy amount of cargo capacity will be needed to build a human colony on the Red Planet.

Megatons per year to orbit are needed for life to become multiplanetary, he tweeted. For a yield of one megaton per year, each Starship needs to deliver 100 tons per flight, according to Musk.

SpaceX says that the Starship and the Super Heavy rocket have a 9 m payload compartment, which is larger than any such payload available at present, or soon. This will enable it to deliver satellites to Earths orbit and beyond, at a lower marginal cost per launch than the current Falcon vehicles. Starships pressurized forward payload volume is greater than 1,000m3, enhancing utilization capacity for in-space activities. The aft cargo containers can also host a variety of payloads, according to a statement on the companys website

He added that there will be a lot of jobs on Mars once the colony is established.The Starship transportation system is still in the design stage.

The Starship transportation system is a two-stage vehicle made up of the Super Heavy Rocket, the booster, and the transport pod--the Starship.

SpaceX intends to ultimately replace its Falcon 9 rocket systems by creating a single reusable transportation unit to service its interplanetary commuting ambitions. The space company intends to redirect resources from Falcon 9 series to the Starship, to help make it an affordable option for people wanting to travel to the moon and more.

The first cargo mission to Mars is planned in 2022. This initial mission will establish the possibility of life on Mars, look for water sources, and establish a small infrastructure.

Another mission in 2024 is planned with cargo and crew both. They are hopeful of setting up a more secure base on Mars to facilitate future missions and the beginnings of colonization of Mars.

SpaceX has already announced its plans to carry fashion innovator and art curator Yusaku Maezawa to fly around the Moon in 2023. Only 24 other people have made it to the Moon to date, the last one being in 1972.

SpaceX will be conducting the first private flight to the Moon, it will be a fly-by of the moon on a weeklong trip.

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SpaceX has ambitions to carry a million people to Mars by 2050, tweets Musk - Technowize

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The Search for Exoplanets Have Revealed a Cold Neptune and Two-Super Earths by Land Based Telescopes – Science Times

Posted: at 5:50 am

Scientists looking up into sky have found good leads that reveal a frigid Neptune and dual Earths bigger than ours. All these are part of five extraterrestrial worlds that are part of five exoplanets, eightexoplanetsin orbit near red dwarfs. This discovery was reported by Carnegie's Fabo Feng and Paul Butler, published in The Astrophysical Journal Supplement Series.

Both earths might be hospitable to future colonization, they revolve around thestars GJ180 and GJ229A. These red dwarfs are the nearest to the sun in terms of distance, observing them will be of import to gain more data via land-based telescopes. Both earths are bigger by 7.5 and 7.9 times more than our earth, they orbit in a duration of 106 and 122 days from calculations made. Nearby is Neptune size planet that is in orbit around GJ433, with indications of frozen water that could be imaged with earth-based telescopes. One of the researchers noted that this Neptune-like planet is the closest to our solar system.

Using the radial velocity method to look for exoplanets in the cosmos aided in the discovery, which is important to astronomers and astrophysicists looking for outer worlds.Radial Velocityworks by detecting planetary wobbles that are a result of the gravity of a planet and a star, this minute and increment changes are detected by advanced tools to measure it. The mass of red dwarfs is lower than other types of stars, the primary types of stars near habitable planets when are found.

Red dwarfs or M dwarfs are usually not as hot as our sun, and widespread all over the galaxy. Where there are an M dwarfs, there will be planets that can contain life and water as well. Lower temperatures of red dwarfs are conducive to have more habitable and water-laden planets, called the habitable zone compare to other stars. This life-giving condition is a boon for astronomers and astrophysicists looking for alternative worlds to terra-form and transfer humanity as another "earth", or a collective of habitable worlds to choose from.

Planets that orbit around these red dwarfs will be tidally locked, which is the same rotation axis is shared by the host M dwarf that is the same. This synchronicity is the same mechanics as the earth and the moon. Synchronous spinning at the axis by exoplanets has a cold and hot side that raises inhospitable conditions for colonizing, which should be considered. One of the better options is GJ180d, which is not locked to the local stars gravitation well, so it will be a better place to live in and it might have existing flora, and fauna.

An alternative option isGJ229Ac, and it is as temperate as our world, but it is super-sized with a brown dwarf. Brown dwarfs are not able to process hydrogen fusion, compared to other stars, it is not as hot. Another brown dwarf called GJ229Ac is one of the first to have its appearance seen, but whether exoplanets is supported that is not known. More is needed to understand how a brown dwarf forms, in brown dwarf based "binary system".

Finding moreexoplanetsand finding more habitable worlds, developing the right tools, and mechanics are important. These will reveal more of the cosmos all the secrets to learn until better tools are available to observe the fringes of the solar system.

Read: 'Cold Neptune' and two temperate super-Earths found orbiting nearby stars

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After 1-Day Weather Delay, SpaceX Succesfully Conducts Abort Test – Weatherboy

Posted: at 5:50 am

A dummy known as Ripley flew to the ISS on the SpaceX Crew Demo flight. After todays test flight of another Crew Dragon craft with other dummies, humans may soon occupy it on a trip to the International Space Station later this year. Image: SpaceX

A day after weather interfered with plans for a test flight, SpaceX had a successful launch and splash-down this morning, putting it on the path to be the first company certified to bring humans to space from U.S. soil since the Space Shuttle program ended in 2011.

At 10:30am today, a SpaceX Falcon 9 rocket carrying the Crew Dragon lifted up from historic Launch Complex 39A at NASAs Kennedy Space Center in Florida. The purpose of this mission is to show the spacecrafts capability to safely separate from the rocket in the unlikely event of an inflight emergency.

This critical flight test puts us on the cusp of returning the capability to launch astronauts in American spacecraft on American rockets from American soil, said NASA Administrator Jim Bridenstine. We are thrilled with the progress NASAs Commercial Crew Program is making and look forward to the next milestone for Crew Dragon.

NASA and SpaceX teams conducted the companys in-flight abort test this morning. Image: SpaceX

As part of the test, SpaceX configured Crew Dragon to trigger a launch escape about 1.5 minutes after liftoff. All major functions were executed, including separation, engine firings, parachute deployment and landing. Crew Dragon splashed down at 10:38 a.m. just off the Florida coast in the Atlantic Ocean while the Falcon 9 was terminated; it had previously flown three missions into space.

As far as we can tell thus far, its a picture perfect mission. It went as well as one can possibly expect, said Elon Musk, Chief Engineer at SpaceX. This is a reflection of the dedication and hard work of the SpaceX and NASA teams to achieve this goal. Obviously, Im super fired up. This is great.

The past few days have been an incredible experience for us, said astronaut Doug Hurley. We started with a full dress rehearsal of what Bob and I will do for our mission. Today, we watched the demonstration of a system that we hope to never use, but can save lives if we ever do. It took a lot of work between NASA and SpaceX to get to this point, and we cant wait to take a ride to the space station soon.Prior to the flight test, teams completed launch day procedures for the first crewed flight test, from suit-up to launch pad operations. The joint teams now will begin the full data reviews that need to be completed prior to NASA astronauts flying the system during SpaceXs Demo-2 mission.While rare, launch problems do occur from time to time. In October 2018, a Russian rocket carrying Russians and American to the International Space Station suffered from an anomaly shortly after launch. In that mishap, the crewed Soyuz capsule successfully deployed from the rocket and returned the people safely to Earth.Todays test shows that SpaceX has a similar program to keep astronauts safe should a problem pop-up as they travel into space.

The Crew Dragon, containing dummies fitted with sensors to collect data on the journey back to Earth, will be recovered and examined over the next several days and weeks. Once all test results are final and SpaceX completes necessary paperwork, they could become the first entity certified for human space travel, with a possible crewed launch to the International Space Station as soon as later this spring.

Beyond the Crew Dragon, SpaceX is also working on another rocket/spacecraft project to bring people and cargo to the Moon, Mars, and beyond. Musk hopes to be able to bring a million people to Mars by 2050 as part of colonization plans there.

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Alain Bizos : Politically Incorrect – The Eye of Photography

Posted: January 18, 2020 at 11:31 am

For its first collaboration with the French artist reporter photographer Alain Bizos, the Polka gallery presents an irreverent pop up exhibition entitled Politically incorrect.

Alain Bizos shared his career between Liberation and the VU agency, the group of graphic designers Bazooka and the monthly Actuel, Nouveau et intressant and thus positioned his work on a thread drawn between the fields of art and information. Since the 1970s, he has claimed himself a committed art activist using humour and derision as his tools.

In 1969, just graduated from the Beaux Arts, he found himself at the heart of the New York avant-garde when he became Armans assistant. He participated in the renewal of conceptual photography by using photography as a support for his proposals, mainly through sequences such as his Robberies: the visitor follows the shoplifting committed by the artist. The stolen object (cricket set, electric spotlight, suitcase) was then exposed and accompanied by a certificate attesting that any person who owns this work is considered to be a fence in the eyes of the law. Bizos asks: is a work of art a commodity like any other?

The artist also entails his gallery owners, his collectors as direct receivers and more generally the spectator, a tacit accomplice to the crime.

It is no coincidence that the artist-activist crossed paths in 1979 with public enemy n 1 Jacques Mesrine, with whom he produced a photo sequences that passed to posterity, and published at the time by Paris Match.

Bizos also portrays himself in wanted notices stolen from New York post offices through the Wanted series.

Politically incorrect will also give pride of place to more recent pieces of Bizos work such as the sequence Bye-Bye Mao, exhibited in 2018 at the Rencontres dArles in the exhibition 100 portraits of the collection of Antoine de Galbert, or the monumental piece Marianne-colre.

The works of Bizos paint a portrait of a personal work with a strong political content, heterogeneous and original but also fiercely funny.

Alain Bizos, born in Paris, student at the National School of Fine Arts, Painting Section and at the Louvre School in Art History. It was in 1969 following his meeting with the visual artist Arman, of whom he became assistant, that he moved to New York. He then produced conceptual photographic sequences, such as Espaces interdits or Robberies which he showed, at the Green Street Gallery in New York in 1970, and at the Ferrero gallery in Nice in 1972, his first personal exhibitions. Making frequent trips back and forth between New York and France, he participated in 1973 in the creation of the daily Liberation, linked with the group of young graphic designers Bazooka and in 1977 he was director of publication of the monthly Un regard moderne. In 1979, it was at the request of Jean-Franois Bizot, that he returned to France to participate as artist-reporter-photographer in the launch of Actual, the monthly New and interesting. His quirky portraits and reports in the form of photo stories mark the visual identity of the monthly through its original treatment of color and framing. In 1986, Christian Caujolle, then head of Liberations photo department, asked him to join him when the Agence Vu was created. In 2015, Alain Bizos left the Agence Vu and continued his work as a freelancephotographer.

His images are part of important collections: from the Museum of Contemporary Art in Hartford-Connecticut (USA) to the Sylvio Perlstein collection, via the collection of the Cartier Foundation for Contemporary Art, the National Fund for Contemporary Art , the Maison Rouge in Paris, and many private collections.

Alain Bizos : Politiquement Incorrect

January 15 to 25, 2020

Polka Galerie

Cour de Venise

12, rue Saint-Gilles, 75003 Paris

http://www.polkagalerie.com

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How Newsom will assist in ‘suicide’ of northern SJ Valley using a straw – The Turlock Journal

Posted: at 11:31 am

If you happen to run into Gavin Newsom persuade him to gowith you to your friendly neighborhood 7-Eleven and buy him a politicallyincorrect Super Big Gulp.

Fill it with Coca-Cola. Its a poison as defined byMichael Bloomberg who wants you to vote for him as Nanny in Chief on March 3 inthe California primary that more people chose than lets say Sprite andOrange Crush. With a little luck the Coca-Cola will run out of syrup just as hefinishes filling the cup.

Make sure that you grab a politically incorrect plasticstraw as well, although a paper straw will do.

Now look toward the Delta. Ask the governor to put the strawinto his Super Bug Gulp and take a swig or two. Once hes got the soda downabout an inch or two ask Newsom to top it off. Since the Coca-Cola is maxedout, hell have to select another source to fill the cup back up.

As any self-respecting pre-teen of days gone-by would know,Newsom is taking the first step toward making a soda concoction thats called asuicide.

You have just given the governor a perfect analogy for hismyopic Delta tunnel plan as well as coined a rallying cry for the nextgeneration of victims of the incredible thirst of the Los Angeles Basin as wellas large corporate farmers that are a large source of the late Assembly SpeakerBig Daddy Jesse Unruhs mothers milk of politics political campaigncontributions.

If you siphon Sacramento River water from the Delta it willcreate a void that has to be filled from somewhere else unless you want severesaltwater intrusion that would turn the Delta into a toxic wasteland for birds,native fish, flora, and even inconsequential things. Those inconsequentialthings are farmers and people that depend on Delta water or water pumped fromaquifers in and around the Delta that would be impacted as salt water replacesfresh water.

Lets return to the 7-Eleven for a second. Most offer othersoda flavors such as Mt. Dew, Sprite or Dr. Pepper. There are usually twoCoca-Cola options due to the larger volume that also requires more tanks ofsyrup as opposed to the other flavors that have less demand and therefore lesssyrup.

The Sacramento River is Coca-Cola. The Stanislaus, Tuolumne,and Merced rivers are the other three soda flavors. Once the Pepsi is siphonedout of the cup that is used to flush the Delta, some soda has to replace it.Thats when the state will create a suicide mix increasing the water flowsfrom the Stanislaus, Tuolumne and Merced watersheds to flush the Delta.

Of course, anyone living in the next Owens Valley betterknown as the Northern San Joaquin Valley would be committing suicide to favorsuch a move.

This is why big water interests in Los Angeles as well ascorporate farmers have managed to convince yet another governor that theNorthern San Joaquin Valley needs assistance to commit suicide which is wherethe myopic tunnel comes into play.

The Department of Water Resources this week officiallyrepackaged the double barrel shotgun aimed at the Delta ecological system aswell as Northern San Joaquin Valley cities and farms as a single barrel byissuing a notice of preparation for the project. Thats the prelude to thelengthy eye-popping environmental review process that is much like theimpeachment of Donald Trump as you already know how it is going to end. In thecase of the myopic tunnel we will be told it will be the best thing forCalifornia since gold was discovered. Thats an appropriate analogy given 172years later we are still dealing with environmental disasters perpetuated inthe name of growing the economy including filling in a third of the SanFrancisco Bay and reshaping and poisoning waterways.

As for two tunnels versus one tunnel, its just like a gun.It only takes one bullet or shot to kill a person. The same is true forsiphoning water and what it will do to the Delta.

One of the more interesting things about the PeripheralCanal 3.0 reboot rolled out this week is the reason why the state must sinkupwards of $20 billion in an investment that doesnt increase the amount ofwater delivered to Los Angeles or big corporate farms by one drop.

Originally we were told the twin tunnels were needed due tothe imminent collapse of levees in the next big quake that would reduce waterflow to the intake to the California Aqueduct pumping stations northwest ofTracy for six months or more forcing Beverly Hills mansion owners to converttheir expansive green estates into hues of yellow and brown.

Given the science was underwhelming, the lack of nearbymajor fault lines, and the historic impact of major Bay Area quakes such as the1906 and 1989 tremblors didnt give the theory much traction with the public,the had to hang the reboot on something else. And they did.

We are now being told its all to stop the horrors of climatechange as the current way fresh water is conveyed through the Delta from theSacramento watershed to hoses of people washing down sidewalks in Los Angelesis just 3 feet above sea level.

That means rising sea levels due to warmer temperatures willswamp the Delta with salt water making water that passes through it no longersuitable for drinking or applying to crops unless it first flowed through adesalination plant just before the water flows into the pipelines of Big L.A.

But if the real issue is now climate change which somemodels say will mean less snowpack with each passing year due to snow in theSierra being replaced extensively by rain, is the myopic tunnel the bestinvestment the state can make? A major reduction in natures reservoir theSierra snowpack that provides most of the above ground source of water inCalifornia will substantially reduce available water.

Toss in the fact a saltier Delta would be a disaster for theecological system that is home to nearly 750 species of plant and wildlifewouldnt a barrier system a modified dike to regulate flows to and from thebay address the most concerns?

The real reason for the myopic tunnel is to assure theimpacts of out-of-basin water users the west side of the southern San JoaquinValley and Los Angeles Basin have minimal loss of water supplies duringdroughts and/or meeting state-mandated or court-ordered fish flows.

In short, Los Angeles will actually get an even bigger gulpof water while the state replaces what they siphon off via a $20 billion strawthat takes water from cities and farms dependent upon the Stanislaus, Mercedand Tuolumne rivers.

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How Newsom will assist in 'suicide' of northern SJ Valley using a straw - The Turlock Journal

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Faulconer Boosts Housing Efforts, Convention Center in Last SOTC – Voice of San Diego

Posted: at 11:30 am

This post originally appeared in the Jan. 16 Morning Report. Get the Morning Report delivered to your inbox.

Mayor Kevin Faulconer promised to continue to focus on addressing the citys homelessness and housing crises in his final State of the City address on Wednesday night.

And he said he was done being politically correct about homelessness.

What Im talking about tonight is obvious to almost anyone walking our streets but considered politically incorrect by many insiders. These are ideas that most people in power actually believe in, but are afraid to say, let alone do, Faulconer said. Drug laws that hurt people, tragic mental illness, public health scares, a historic housing shortage They all must be addressed to solve the homeless crisis.

Faulconer committed Wednesday to championing reforms to state policies he said have hampered cities ability to aid homeless Californians struggling with addiction. He did not elaborate on the specifics of those efforts Wednesday night but cited Proposition 47, which reduced many drug crimes to misdemeanors, and Proposition 57, which led to an overhaul of the states prison parole system.

The mayor said he also plans to work with county officials to open a county-run shelter, move people with substance abuse issues into residential care and deploy mental health teams at existing city shelters. County spokespeople did not immediately respond to requests from VOSD about those initiatives on Wednesday night.

On Faulconers watch, the city hasramped up police enforcementaffecting homeless San Diegans, an approach that advocates and the citys newhomelessness action plan have scrutinized. Hes also vastlyexpanded homeless servicesin the city and pursued a slew of reforms to try to address lagging housing production, particularly for middle-class and low-income San Diegans.

Faulconer pledged to stay committed to those efforts in his final year in office.

He said he plans to push forward this spring a series of reforms hes dubbed hisComplete Communities initiativethat are meant to encourage more homebuilding citywide, particularly near transit stops.

The mayor also encouraged city voters to backMeasure C, a March hotel-tax measure that would fund a Convention Center expansion, homeless initiatives and road repairs. He noted that the measure would provide the citys first dedicated funding for homelessness and road repairs and pay for a Convention Center expansion supporters have said would bolster the local economy.

If you cant believe this is the 10th State of the City when a mayor talks about theConvention Center expansion, you can make it the last time by voting yes on Measure C, Faulconer joked.

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Faulconer Boosts Housing Efforts, Convention Center in Last SOTC - Voice of San Diego

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Left and right should learn to take a joke, not censor them – The Guardian

Posted: at 11:30 am

In retaliation, Ayatollah Khomeini should tweet a list of 52 sites of beloved American cultural heritage that he would bomb.

So wrote Asheen Phansey, an adjunct professor at Babson College in Massachusetts. He added that cultural sites to target might include the Mall of America and the Kardashian residence. Not the funniest of jokes (and not helped by the fact that Khomeini died more than 30 years ago) but definitely a joke and a response to Trumps tweet that America would target 52 Iranian sites, including those of cultural significance, if Tehran did retaliate for the assassination of General Qassem Suleimani.

It led to an inevitable outpouring of outrage on Twitter from conservative snowflakes. By the end of the day, Phansey was no longer teaching at Babson. The post did not represent the values and culture of the College, read a statement. The college condemned any type of threatening words and/or actions condoning violence and/or hate. Its just as well that John Betjeman was never a professor at Babson.

Much is made today of liberals demanding action against those using offensive language or making politically incorrect jokes. The Babson case shows conservatives are equally easily offended.

Across the Atlantic came another illustration of rightwing outrage. The release of Tolo Tolo, an Italian film satirising anti-migrant hysteria, caused anger among conservatives who had thought that it would be hostile to immigrants. It is too politically correct, claimed a senator from Silvio Berlusconis Forza Italia party. Which only goes to show that its politically correct has come to mean little more than I dont like it.

The Babson case also shows the dangers of the left demanding censorship of offensive speech. Its not just speech the left thinks is politically incorrect that will get censored.

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Left and right should learn to take a joke, not censor them - The Guardian

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