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Category Archives: Transhuman News

Area’s Youth of the Year honored | Local News – Rocky Mount Telegram

Posted: February 27, 2020 at 1:55 am

Red Carpet: check. Crowd of proud community members: check. Three young shining examples of leadership from the Boys & Girls Clubs: triple check.

On Tuesday night, the Boys & Girls Clubs of the Tar River Region recognized Nia Ewuell, Caleb Woodard and Elijah Sellars as finalists in the regional level of the Youth of the Year competition. Of these three, one also was selected as the winner and will receive a $1,000 scholarship and the chance to compete in the state level of the competition.

I want to tell these kids and remind everyone that the world needs contributions from everyone, said Ron Green, CEO of the club. Its not just his story or her story. Its our story.

The winner was announced at the end of the show. Leading up to the report, attendees were able to enjoy a step dance performance by a group in the club, listen to a speech by Green that rhymed impressively all the way through and talked about famous African-Americans such as Frederick Douglass and Serena Williams, sing along with Tobias Hopkins to U2s Lean On Me and watch in amazement as another young man from the club played an electric guitar along to Michael Jacksons Rock the Night Away.

Everyone was so excited to clap for him that he had to give a thumbs up for when he was done as small rounds of applause kept breaking out during the song.

The audience also heard from the three finalists. Prior to the event, contestants had been judged by six members of the community for things such as academic success, public speaking ability and demonstrated leadership within the club. A shopping trip for formal dress clothing was sponsored by Rocky Mount Toyota.

Woodward spoke first, dressed in a classy blue suit. He thanked the club for the love and time they had poured into him and talked about how, moving forward, he wanted to focus on addressing the growing obesity rate in youth.

Sellars, in a sharp burgundy suit and bow tie, brought a remarkable energy to the stage. His speech sounded as though it was a series of journal entries, all beginning with: Are you there, God? Its me, followed by discussion of a rough childhood involving topics such as drugs and an absent father, as well as the happiness he found in the Boys & Girls Clubs.

In a stylish pink blouse, black suit and heels, Ewuell spoke about how the club influenced who she has become, recognizing the empathy and acceptance she has learned and her plans to continue to develop those traits as she becomes a lawyer.

All three received a commemorative medal and a gift. Woodward was announced as third, leaving Sellars and Ewuell waiting at the front of the stage.

Green paused for a long moment, then finally announced: Of our two remaining, it couldve been either one. Tonight, our winner is Elijah Sellars.

As soon as Sellars was announced, he and Ewuell grabbed onto each other in a hug, with Woodward joining soon after. After several pictures with the oversized check and various members of the club, Sellars was able to approach the podium with his closing remarks, a grin stretched wide across his face.

To all of the kids from the Boys & Girls Club here today, and everyone else too, we are the future, but we are also the present, he said. Its up to us. I challenge each one of us to start shaping our own futures.

Sellars, a sophomore, hopes to one day attend either N.C. State University or Duke University to study genetic engineering. He plans to use the scholarship to help pay for his education, or, if expenses can be covered another way, use the money to invest in another youth of the year by sponsoring a shopping trip or another way to give back.

What I learned from the Boys & Girls Club is just how important it is to lean on one another, Sellars said. Im excited to represent kids Ive known my whole life, kids I know and love, in this competition. Im nervous about the next step, of course, but I know I have my clubs support.

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Texas coronavirus cases climb to three in San Antonio – The Texas Tribune

Posted: at 1:55 am

Two more cases of the new strain of coronavirus have been confirmed at the San Antonio military base where some evacuees from a cruise ship were quarantined Monday, the Centers of Disease Control and Prevention said at a press conference Friday. This brings the number of confirmed Texas cases of the strain named COVID-19 to three.

The two evacuees were among 329 Americans repatriated against the CDC's recommendation after disembarking from the Diamond Princess off of Japan. Another 16 cruise ship evacuees quarantined in California and Nebraska have also been confirmed to have coronavirus.

"[The passengers] are considered at high risk for infection, and we do expect to see additional confirmed cases of COVID-19 among the passengers," said Nancy Messonnier, director of the National Center for Immunization and Respiratory Diseases, during the press conference.

There are also several Americans hospitalized in Japan who are "seriously ill," she said.

The first Texas case was confirmed Feb. 13 when one of 91 Americans evacuated from the Hubei province of China, the epicenter of the outbreak, was hospitalized. The remaining 90 Americans were released from the San Antonio base Thursday because they showed no symptoms after a 14-day quarantine.

The World Health Organization declared COVID-19 a public health emergency by last month. According to the latest CDC report, there are over 75,000 confirmed cases worldwide, and the death toll has surpassed 2,000. But outside of China, there have been only three fatalities, and none in the U.S.

The total number of confirmed U.S. cases is 34. However, the CDC makes a distinction between cases among repatriated Americans and all other U.S. cases, as the former aren't an accurate representation of how the virus is spreading within the country, according to Messonnier.

"We don't yet have a vaccine for this novel virus, nor do we have a medicine to treat it specifically," Messonnier said.

The goal now is to slow the introduction of the virus into the U.S. to buy time to prepare the community for more cases and possibly sustained spread, she added.

Two elderly Japanese passengers aboard the Diamond Princess died after testing positive for the virus, Japan's health minister said Thursday.

Researchers at the University of Texas at Austin are working on a vaccine, and a Houston-based genetic engineering company announced this week it finished developing one. However, the Food and Drug Administration has not yet approved a vaccine.

Disclosure: The University of Texas at Austin has been a financial supporter of The Texas Tribune, a nonprofit, nonpartisan news organization that is funded in part by donations from members, foundations and corporate sponsors. Financial supporters play no role in the Tribune's journalism. Find a complete list of them here.

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You Are but Dust, and to Dust You Shall Return – Christianheadlines.com

Posted: at 1:55 am

As Western culture becomes more and more secular, or to use Charles Taylors fascinating word disenchanted, traditions and practices once largely normal seem more and more strange. Large families, choosing church over Little League, or smudged foreheads just arent as normal as they used to be, and the second glances or raised eyebrows they create reveal more than a confusion about the thing itself.

In fact, Im not sure there is a Christian observance that more directly collides with the widely accepted values of secularism than the imposition of the ashes, a tradition that goes back about ten centuries and marks the beginning of the season of Lent on the Church calendar.

Like Advent, the season of Lent is about preparation. Before Christmas, our Christian forebears thought it wise to prepare a bit, and that by diving deeply into Old Testament promises and prophecies wed better understand the birth of Christ in the full context of redemptive history. So too, in Lent, our Christian forbears thought it wise to prepare for Holy week, especially for celebrating the resurrection on Easter Sunday.

A key distinction is that Lenten disciplines, beginning with Ash Wednesdays reminder that You are dust and to dust you shall return, place our celebration of resurrection in the context of our humanity, both our mortality and our fallenness. Even if the church calendar and its accompanying disciplines is not part of your church tradition, these two aspects of our humanity deserve our focused, intentional, and extended reflection.

Of course, most Christians would quickly reply that, of course, sin and death affect us all post-Eden. The problem is, in a secular culture, these beliefs that are crucial to a Christian worldview can be subtly secularized in our own hearts and minds.

Years ago, when my grandfather was dying, he suffered terribly for three or four months. In sorrow, I asked my pastor, Why doesnt God just take him? I expected him to say something along the lines of, Well, God has His ways, and His own timing, but instead he said something Ill never forget: Because your grandfather needs to know his mortality before he meets his maker.

What Ponce de Leon once sought in the waters of a Fountain of Youth, we still seek today via genetic engineering, eugenics, and other technologies. In other words, we seek control over this world and even over death itself.

Despite our search, death remains the universal problem of the human condition, one that afflicts us all. A secular culture is led by the reality of death to fear death itself, so that we either attempt to control death or distract ourselves from the thought of it. As a result, we learn to live life in light of the moment, rather than eternity.

The reality of death should, instead, remind us to fear God. That after death, we will meet the maker of life, is worth pondering, not just at the moment of death, but constantly throughout our lives.

Theologian Craig Gay warned in his book The Way of the Modern World that many of us who believe in God live as if God were largely irrelevant to most of life. The reminder of our mortality in the words, You are but dust and to dust you shall return, is a wonderful antidote for what he called practical atheism.

Just like with the idea of mortality,our understanding of our own sinfulness is also under threat of being secularized in our own minds. In a culture committed, in the name of freedom, to removing the categories of sin or guilt, one quick to give away nearly universal get-out-of-jail-free cards in the name of sexual freedom, too many Christians lose any abhorrence for that which ought shock and shame us.

Perhaps this is why the salvation brought by Christs life, death, and resurrection is so often described as a wonderful example of love and sacrifice or how to gain purpose and perspective, but so rarely in the terms of judicial forgiveness and cosmic victory that Paul and Peter and Jesus Himself so often used.

Being confronted with our own sinfulnessis certainly no fun, but God graciously does it. After all, the cruelest thing to tell someone whos not okay is that they are, as both secularized cultures and secularized churches too often do. Repentance is a gift, the only way forward for those on the edge of the moral abyss. Its proof that God is kind, the Scriptures say.

We just dont hear these things often enough. So, thank God for Lent.

Publication date: February 26, 2020

Photo courtesy: Ahna Ziegler/Unsplash

BreakPointis a program of the Colson Center for Christian Worldview. BreakPoint commentaries offer incisive content people can't find anywhere else; content that cuts through the fog of relativism and the news cycle with truth and compassion. Founded by Chuck Colson (1931 2012) in 1991 as a daily radio broadcast, BreakPoint provides a Christian perspective on today's news and trends. Today, you can get it in written and a variety of audio formats: on the web, the radio, or your favorite podcast app on the go.

John Stonestreet is President of the Colson Center for Christian Worldview, and radio host of BreakPoint, a daily national radio program providing thought-provoking commentaries on current events and life issues from a biblical worldview. John holds degrees from Trinity Evangelical Divinity School (IL) and Bryan College (TN),and is the co-author of Making Sense of Your World: A Biblical Worldview.

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A Hereditable Mutation of MSH2 Gene Associated with Lynch Syndrome in | CMAR – Dove Medical Press

Posted: at 1:55 am

Wei-Hua Shao,1 4,* Cheng-Yu Wang,4,5,* Lei-Yun Wang,1 4 Fan Xiao,1 4 De-Sheng Xiao,6 Hao Yang,4,5 Xue-Ying Long,7 Le Zhang,8 Heng-Gui Luo,9 Ji-Ye Yin,1 4 Wei Wu4,5

1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410078, Peoples Republic of China; 2Institute of Clinical Pharmacology, Central South University; Hunan Key Laboratory of Pharmacogenetics, Changsha 410078, Peoples Republic of China; 3Engineering Research Center of Applied Technology of Pharmacogenomics, Ministry of Education, Changsha 410078, Peoples Republic of China; 4Department of Geratic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, Peoples Republic of China; 5National Clinical Research Center for Geriatric Disorders, Changsha, Hunan 410008, Peoples Republic of China; 6Department of Pathology, Xiangya Hospital/School of Basic Medicine, Central South University, Changsha 410078, Hunan, Peoples Republic of China; 7Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, Peoples Republic of China; 8Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, Peoples Republic of China; 9Department of General Surgery, The Central Hospital of Xiangtan City, Xiangtan, Hunan, Peoples Republic of China

*These authors contributed equally to this work

Correspondence: Wei WuDepartment of Geratic Surgery, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha 410008, Hunan, Peoples Republic of ChinaTel +86 731 89753053Email wwtw1972@126.com

Purpose: In order to clarify which variants of the MMR gene could provide current healthy members in affected families a more accurate risk assessment or predictive testing.Patients and Methods: One family, which meets the criteria according to both Amsterdam I/II and Bethesda guidelines, is reported in this study. The proband and some relatives of the patient have been investigated for whole genome sequencing, microsatellite instability, immunohistochemical MMR protein staining and verified by Sanger sequencing.Results: A heterozygous insertion of uncertain significance (c.420dup, p.Met141Tyrfs) in MSH2 gene was found in proband (III-16) and part of His relatives. The variant was associated with a lack of expression of MSH2 protein (MMR deficient) and high microsatellite instability analysis (MSI) status in tumor tissues of LS patients. In addition, we found that the variant could affect the expression of MSH2 and the response to chemotherapy drugs in vitro.Conclusion: We identified an insertion mutation (rs1114167810, c.420dup, p.Met141Tyrfs) in MSH2 in LS using whole genome-wide sequencing (WGS). We further confirmed that this mutation plays an important role in LS patients of this pedigree based on in vivo and vitro study.

Keywords: Lynch syndrome, genetic variation, mismatch repair gene, MSH2, chemotherapy resistance

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Global Protein Sequencing Market Drivers, Restraints & Opportunities During the Forecast Period, 2019-2026 – ResearchAndMarkets.com – Business…

Posted: at 1:55 am

DUBLIN--(BUSINESS WIRE)--The "Protein Sequencing Market by Product and Service Technology and Application: Global Opportunity Analysis and Industry Forecast, 2019-2026" report has been added to ResearchAndMarkets.com's offering.

The global protein sequencing market size was valued at $ 5,399.9 million in 2018 and is expected to reach $ 9,926.7 million by 2026, registering a CAGR of 7.8% from 2019 to 2026.

Protein sequencing provides information regarding the amino acids that make up a protein. While performing the sequencing process, amino acids are sequentially removed from the N-terminal end of the protein strand and identified in the order they occur in the protein. Protein sequencing finds its wide applications in the field of genetic engineering, and biotherapeutics. There are two main technologies available for protein sequencing namely Edman degradation and mass spectrometry. Edman degradation is considered as the gold standard for protein sequencing.

The major factors contributing to the growth of the protein sequencing market include surge in focus on biotherapeutics development biotechnology and pharmaceutical companies in various developing and developed regions. Technological advancements in de novo peptide-sequencing methods and analytical methods, with the application of neural networks, have opened new avenues in the market. However, high cost of infrastructures and the required equipment such as mass spectrometers, hamper the market growth. On the contrary, technological advancements for the identification of isobaric residues in protein sequences are expected to create lucrative opportunities in the near future.

KEY BENEFITS FOR STAKEHOLDERS

Key Findings of the Protein Sequencing Market:

Key Topics Covered:

Chapter 1: Introduction

1.1. Report Description

1.2. Key Benefits For Stakeholders

1.3. Research Methodology

1.3.1. Secondary Research

1.3.2. Primary Research

1.3.3. Analyst Tools & Models

Chapter 2: Executive Summary

2.1. CXO Perspective

Chapter 3: Market Overview

3.1. Market Definition And Scope

3.2. Porter's Five Forces Analysis

3.3. Market Share Analysis

3.4. Market Dynamics

3.4.1. Drivers

3.4.1.1. Increasing Focus On Target-Based Drug Development

3.4.1.2. Advancements In Mass Spectrometry And Analytical Techniques

3.4.2. Restraints

3.4.2.1. Dearth Of Skilled Researchers And Laboratory Professionals

3.4.3. Opportunities

3.4.3.1. Opportunity In Computational Proteomics

Chapter 4: Protein Sequencing Market, By Products & Services

4.1. Overview

4.2. Reagents & Consumables

4.3. Instruments

4.4. Analysis Product

4.5. Protein Sequencing Services

Chapter 5: Protein Sequencing Market, By Technology

5.1. Overview

5.2. Mass Spectrometry

5.3. Edman Degradation

Chapter 6: Protein Sequencing Market, By Application

6.1. Overview

6.2. Biopharmaceuticals

6.3. Biotechnology Research

Chapter 7: Protein Sequencing Market By Region

7.1. Overview

7.2. North America

7.3. Europe

7.4. Asia-Pacific

7.5. LAMEA

Chapter 8: Company Profiles

8.1. Charles River Laboratories

8.2. Shimadzu Corp.

8.3. Agilent Technologies

8.4. Thermo Fischer Inc.

8.5. Selvita

8.6. Rapid Novor.

8.7. Sgs

8.8. Proteome Factory

8.9. Bioinformatics Solution

8.10. Water Corporation

For more information about this report visit https://www.researchandmarkets.com/r/tahl8q

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Global Protein Sequencing Market Drivers, Restraints & Opportunities During the Forecast Period, 2019-2026 - ResearchAndMarkets.com - Business...

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Healthy-ish French Fries Are Now a Thing Thanks to Genetic Redesigning – Observer

Posted: at 1:55 am

With Calyxt making fried foods healthier, maybe celebs will actually eat them instead of just posing with them. Rich Polk/Getty Images for The Weinstein Company

Eat up, America. Your favorite standby comfort foodthose slightly greasy, salted-just-right French fries that have thrown many a dieter off the straight and narroware now healthy. Or at least healthier than they ever have been, thanks to food-tech disruptor Calyxt (pronounced Kay-Lix with an aspirated t at the end) and its breakout vegetable oil, which is designed with less saturated fat and more healthy oleic acid than typical unmodified frying oils.

I first stumbled across Calyxts healthy frying oil at the most unlikely of places: the Minnesota State Fair,a 320-acre mecca of unhealthy eating, butter sculptures, live farm animal births and other assorted curiosities.

SEE ALSO: How Blue Apron Became a Massive $2 Billion Disaster

Any good Minnesotan worth his weight in walleye, even those of us like me who have lived all over the world, will always make a point to come back to our native Land of 10,000 Lakes in late August, in part so we can take in one of the states few months of non-sub-zero temperatures, but also because the second half of August is precisely when we can visit the two-week affair known among locals as the The Great Minnesota Get-Together. Its the largest of its kind in the country, and last years attendance drew in over two million visitors, meaning over a third of all Minnesotans took a day out of their lives to join in on the perennial celebration.

At last years gathering, word was spreading quickly that the Ball Park Caf, a long-time state fair staple, known for its famous beer selection, burgers and garlic fries, had switched to Calyxts healthier vegetable oil for all of its frying needs. Given that the fair happened to fall just as I was several weeks into one of my many concerted efforts to finally get back in shape, I was intrigued.

I was expecting the fries I ordered to taste somehow artificial or rubbery, as do many healthy versions of other foods, but the flavor and consistency of the Calyxt-fried Freedom Fries was exactly as one might expect from a normal bath of hot oilcrispy and yummy. Decadence never tasted so good.

Several weeks after the fair, I looked up the company behind this healthy oil and scheduled a meeting with Calyxts communications head, Trina Lundblad and company CEO Jim Blome. We decided to meet at their offices, a sleek, ultra-modern building in a Minneapolis suburb, overlooking a large swath of prairie grass and pristine crop rows.

The Calyxt headquarters have a definite Silicon Valley feel. Were not an ag company; were a tech company that is applying its IP to the ag sector, said company spokeswoman and communications head Trina Lundblad. Courtesy of Calyxt

For the next several hours that I spent touring the Calyxt headquarters, I came to realize that I was not just visiting, contrary to my expectations going in, another food-based CPG company simply riding the wave of a popular new frying oil with a healthy twistI was at ground zero of the tech revolution in agriculture, where genome editing is revolutionizing the nutritional attributes of the foods we, as humans, will need to continue as a species in the years and centuries to come.

If that sounds like a big deal, its because it is.

Calyxt describes its oil, the product of an improved soybean plant, as having the heart-healthy fat profile of olive oil without the distinctively earthy aftertaste that is fine for spaghetti, but less so for waffles or fried chicken. By using a breakthrough gene-editing technology, Calyxt is engineering an entirely new set of processes for improving the genetic profile for many staples of the nutritional supply chain without introducing transgenic, foreign properties into the mix; Calyxts technology stands out in that it is simply accelerating and improving upon what nature would have probably gotten around to eventually on its own, only several millennia later.

Importantly, the process used by Calyxt, which relies on DNA-cutting enzymes that thankfully go by the abbreviation TALEN (transcription activator-like effector nuclease), sidesteps much of the public and regulatory outcry often associated with traditional GMOs (genetically modified organisms), in which an organisms genetic makeup has been modified in a laboratory using transgenic technology that combines, in a sort of Frankenstein-esque way, plant, animal, bacterial and virus genes that do not occur in nature or through traditional crossbreeding methods.

Calyx, which is a publicly-traded company on the NASDAQ, is improving upon the farm to table fever, by starting upstream.

Way upstream.

Calyxts unique engineering process begins in the high-tech labs on the top floor of the companys headquarters, where a team of scientists reconfigure gene molecules on large computer monitor screens before instructing robotically controlled laboratory pipettes to do their thing. Later, embryonic plant cells are transferred to petri dishes that deliver the customized TALENs, which are then bathed in stimulating hormones and left to grow until they become big enough to see if the edits made upstream in the top floor lab were successful.

Plants that meet the designer teams original specs get pampered in high-tech temperature-regulated nurseries before later graduating to a greenhouse or to the small outdoors plot trials that abut the Calyxt headquarters. From the top performing plants, Calyxt begins developing seed banks that will eventually be sold to farmers.

But that is only the beginning. Its here, at this leg of the business, where Calyxt is positioning itself for long-term, paradigm shifting growth at the crossroads of technology and agriculture.

Jim Blome, the CEO of Calyxt, grew up in a family farm in central Iowa. Today, he leads a company that is playing a major role in defining the future of food on a global scale. Courtesy of Calyxt

Unlike most biotech companies that play in the broader competitive landscape of gene-editing, Calyxt is unique in that it is vertically integrating, contracting with farmers across the Midwest to grow its gene-edited, high oleic soybeans. Earlier this month, the company achieved an important milestone, having successively contracted 100,000 soybean acres with U.S. farmers, more than doubling the size of its planted acres from the previous year. Calyxt CEO Jim Blome lauded the achievement stating that 100,000 contracted acres will support market demand for our high oleic soybean oil.

Calyxts scientists design gene-editing molecules on computer screens, then use robots to build them using a set of DNA-cutting enzymes called TALENs, which are later transferred to petri dishes for analysis. Courtesy of Calyxt

After the growing season, just a few weeks after the Minnesota State Fair wraps up, Calyxt exercises its contracts to buy back the beans from the farmers at a premium to market prices and crushes them to make its healthy, french fry-friendly oil, which it is currently shipping across the country to food services companies and restaurant chains.

Farmers love the higher-than-market commodities prices Calyxt agrees to pay them. The food services sector loves the healthy aspects of the Calyxt end-product, which also has a reuse rate far more efficient than other oils on the market. And Calyxt loves sitting in the middle of both the supply and distribution chains.

I have spent my life in agriculture, and there is nothing as revolutionary happening around genome editing as what we are doing at Calyxt, added Blome, who previously served as the president and CEO of the North American Crop Science division of Bayer, the German multinational pharmaceutical and life sciences juggernaut. We are developing a foundation for the future of global agriculture through precision plant breeding and advanced analytical tools to solve complex challenges with system-based approaches. Tillable land is growing increasingly scarce, populations are growing and the earth is warming, and frankly, we arent ready for what this will mean even five or 10 years down the road.

What we are doing at Calyxt is harnessing the technology that will enable the entire global nutritional and industrial supply chain to adapt to these seismic changes underfoot. And were doing it in a responsible, ethical manner, that brings new opportunities to U.S. farmers, added Blome.

The Calyxt chief isnt simply talking about healthier frying oils, there is a much, much bigger play in the offing: Calyxts technology can be harnessed to address some of the most pressing concerns across all of food and nutritionfrom removing the allergens from nuts and peanuts, to designing better cereal plants, such as wheat, that not only deliver better yields but also address common allergies and afflictions like gluten intolerance. Tubers, tree fruits, CBD productsthe list of potential applications for Calyxt genome-editing is nearly endless.

Where high-tech meets agriculture. Calyxt researchers and plant scientists use state-of-the-art aeroponics growing facilities to iterate on plant-based genome editing. Courtesy of Calyxt

Chris Neugent, a veteran food marketer and former CEO of Post Consumer Brands, the maker of everything from Oreo Os to Grape-Nuts, sits on the board of Calyxt, bringing mission-critical consumer marketing and story-telling gravitas to a company known best for its high-tech bioengineering.

If the Calyxt story was a book, then you could say we are still in the first chapter, probably still on page one. Our work with smarter, healthier soybean oilsas groundbreaking as it isis still proof of concept. As we scale our business and begin adding more products, the market will begin to see us not as the healthier french fry guys but as a company that is revolutionizing next-generation nutrition in agriculture, observed Neugent. We are literally laying track for the biggest agricultural revolution since the transformation of human societies from hunting and gathering to farming. Its that big.

This Second Agricultural Revolution Neugent is alluding to envisages a not-so-far-off future in which Calyxt is redesigning crops to better withstand the massive changes underfoot caused by global warming, over-population and other seismic shifts affecting the future of food.

A young soybean plant flowers inside the Calyxt high-tech laboratory facilty. Courtesy of Calyxt

Like any industry that is shaking up the status quo, Calyxt is beginning to encounter its share of crosscurrents. So far, at least, U.S. regulators seem to be of the opinion that as long as Calyxt is making genetic alterations that could have conceivably occurred naturally, as opposed to other transgenic techniques used in GMOs, no special regulation is needed.

Other incumbent seed engineering companies have dabbled in the high oleic soybean space, but for the most part, they have come at the challenge through a more conventional gene-editing approach, which mixes in organisms that do not naturally conjoin outside of a laboratory, necessitating additional layers of regulatory safeguards.

Calyxt is using high-tech genome editing to serve up healthier versions of the same delicious plant-based foods that we have eaten for decades. Courtesy of Calyxt

For now, Calyxts approach doesnt require any additional oversight or specific product labeling, nor do company executives feel that any will be required at any point in the foreseeable future. The 2018 USDA-released GMO labeling requirements defines bioengineered foods as those containing detectable genetic material that has been modified through lab techniques that cannot be created through conventional breeding or found in nature. As a result, Calyxt is not subject to any additional regulatory or labeling requirements, which is allowing the company to forge ahead on multiple fronts. The company is already engaged in early experimentation with genome edited wheat plants, and it has scores of other applications in development.

For now, Calyxt is a still a small company, but one poised to make a big impact on the global food market.

However, for most of usat least those of us that just like to be able eat French fries from time to time and not feel too bad about it the next dayCalyxt is performing an equally important service on par with helping prepare global food sourcing for the impacts of climate change; they are giving us peace of mind the next time we hit the state fair, or anywhere else where Calyxt-fried French fries are being served.

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Pompeo accuses China and Iran of censoring information about coronavirus outbreaks – ABC News

Posted: at 1:47 am

As the novel coronavirus continues to spread around the globe, Secretary of State Mike Pompeo on Tuesday accused the governments of China and Iran of censoring information about the outbreaks in their countries and putting the rest of the world at greater risk of its spread.

The top U.S. diplomat's sharp tone towards Beijing was matched by Health and Human Services Secretary Alex Azar, who told Congress on Tuesday that the world is not getting reliable data out of China on issues like mortality rates.

But President Donald Trump seems to be out of sync with both of his Cabinet members and other top officials, praising Chinese President Xi Jinping and his government's handling of the outbreak even as his own administration's response comes under fire from Republican and Democratic members of Congress.

President Donald Trump and China's President Xi Jinping arrive for a state dinner at the Great Hall of the People, Nov.9, 2017 in Beijing, China.

"Censorship. It can have deadly consequences," Pompeo said Tuesday at the State Department. "Had China permitted its own and foreign journalists and medical personnel to speak and investigate freely, Chinese officials and other nations would have been far better prepared to address the challenge."

The flow of accurate information out of China, he added, is critical to assisting not just the Chinese people, but also "citizens across the world." He called on all governments to "tell the truth about coronavirus and cooperate with international aid organizations."

Testifying before the Senate Appropriations Committee, Azar said the administration is also uncertain if the data provided by China on the novel coronavirus outbreak has been full and transparent.

But both of those were at odds with Trump's own remarks just two days ago, praising Xi for "working very, very hard" and "doing a very good job."

"It's a big problem, but President Xi, he's working very hard to solve the problem, and he will solve the problem," Trump told reporters at the White House Sunday.

Trump also showered praise on his own administration's response in the U.S., saying Tuesday in India, "We have very few people with it. ... We're really down to probably 10. Most of the people are outside of danger now."

There have been 57 confirmed cases of the virus in the U.S., with three now released from hospital and no longer thought to be contagious. The majority of those -- 43 of the 57 -- are Americans repatriated from the Diamond Princess cruise ship or Wuhan, China, the epicenter of the outbreak. Only 14 are individuals that either arrived in the U.S. from China and checked into a hospital or caught the virus in the U.S. from a loved one who had traveled overseas.

But officials from the Centers for Disease Control and Prevention warned Tuesday that the most recent data suggests another level of virus spread globally, with cases identified in more countries now and another level of virus spread.

People stand on a street behind a barrier to stop others from entering, in Wuhan in China's central Hubei province, Feb. 23, 2020.

"The data over the last week has raised our level of concern," said Dr. Nancy Messonnier, director of the CDC's National Center for Immunization and Respiratory Diseases.

During his news conference in India, Trump also said the U.S. is "very close to a vaccine."

But his acting Homeland Security Secretary Chad Wolf told Congress Tuesday the U.S. was at least "months" away from developing one, with other advisers testifying one was still a full year away.

The various answers vexed Republican Sen. John Kennedy, who told Wolf his "numbers aren't the same as the CDC's. ... Don't you think you oughta contact them?"

Trump's administration has requested $2.5 billion from Congress for emergency supplemental funds to combat COVID-19, the virus's formal name. That funding would come from a $1.25 billion emergency cash requested from Congress as well as reprogramming existing money, including money Congress allocated to fight Ebola.

Democrats condemned the move as both insufficient to deal with the crisis and a short-sighted effort "to steal funds dedicated to fight Ebola," in the words of Sen. Chuck Schumer, amid the second largest outbreak of that deadly disease still lingering the Democratic Republic of Congo.

Secretary of State Mike Pompeo speaks during a briefing at the U.S. Department of State, Feb. 25, 2020, in Washington, D.C.

The request "is indicative of his towering incompetence and further proof that he and his administration arent taking the coronavirus crisis as seriously as they need to be," the Senate Democratic Minority Leader added Monday.

It's not just Democrats, however, who have challenged the administration's response. Chair of the Senate Appropriations Committee, Sen. Richard Shelby, R-Ala., told Azar the administration's "request... is low-balling it possibly, and you can't afford to do that. ... If you low-ball something like this, you'll pay for it later."

Trump's top diplomat for Europe and his State Department also warned that Russia was spreading disinformation about the novel coronavirus outbreak on Saturday. Acting Assistant Secretary of State for Europe Philip Reeker and the agency's Global Engagement Center, which combats terrorist propaganda and foreign government disinformation, told AFP news agency that thousands of Russian-linked social media accounts are actively spreading alarm about the outbreak in a coordinated effort, including accusing the U.S. of creating the virus.

Pompeo said nothing about Russia's role Tuesday. But he did attack Iran's government for censorship as well.

"The United States is deeply concerned by information indicating the Iranian regime may have suppressed vital details about the outbreak in that country," he said, noting Iran is second to China in COVID-19 deaths.

Dr. Iraj Harirchi, the head of Iran's counter-coronavirus task force, tested positive for the virus himself, authorities announced Tuesday -- one day after he appeared at a news conference downplaying the danger posed by the outbreak in Iran and opposing a quarantine of Qom, the city with the largest number of infected patients and fatalities in Iran.

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Art and Censorship: An artist’s "too spicy" video that has censored the city of San Antonio – AL DIA News

Posted: at 1:47 am

"The past never disappears, we are stuck with it, just like we are stuck within modernity. One just has to negotiate how to live with and against it at once," says Xandra Ibarra, aka La Chica Boom, the disruptive character she created and who the government of San Antonio, Texas, has been quick to suppress in the 21st century. Yes, we' re stuck.

Her video artwork "Spictacle II: La Tortillera" (2014) has been removed from a group show at the city's Arts Center for being considered "obscene." It didn't help that the curators of XicanX: New Visions - the exhibition that included the video art piece exploring the Chicanx and Latinx identity - had agreed to project the video in a curtained space and with a warning, officials censored it anyway.

Perhaps because, as Ibarra insists, while art is not required to be political or combative, "the display of sexual content continues to cause anxiety," adding that the goal of censoring works that address sexuality and racialized sex is the system's enforcement of "sexual normality."

A normality, or heteronormality, that the artist strikes like a piata filled with clichs and conventions. That's why, because she doesn't "marry" anyone, she's so annoying for some. Because there is no way to classify her; hers is the art of transgression.

In the video, La Chica Boom is shown as a Mexican housewife masturbating with a pot of spice and two tacos. That's what they'll tell you at first glance.

However, the artist's explanation does more justice to the meaning of the work:

"I used sexualized tropes of Mexicanidad to create a parodic persona, called La Chica Boom. Through this self-other, I explored the embodiment of what I call spichood or my own racial and sexual abjection, themes mostly taboo in activist and community organizing circles I belonged to," she tells us.

"La Tortillera" - a name for lesbian women, an insult or not depending on who's talking - is a long-running work. Ibarra had begun to use burlesque and Mexican "low-brow" humor to conceive a series of performances that she called "spictacles" that were performed in bars and nightclubs and with which she sought to laugh at depictions of Mexican and Chicano sexuality and gender.

"In these performances, I perverted Mexican iconographic symbols (like cockroaches, Catholic virgins, piatas, Mexican wrestlers/Luchadores, hot sauce) by combining them with sex acts like live masturbation, fisting and sex. While humor was very much a central part of this work, I didnt have the intention to work toward recuperating these racialized sex acts; instead this project was an attempt to inhabit my sexed spichood and hyperbolize my supposed differences to discover queer forms of pleasure," she concludes.

However, not everyone thought so...

Moral in a taco

"It was a decision that the city had all the right to make in a space owned by San Antonio," said the director of the Department of Art and Culture, Debbie Racca-Sittre, who came out in the face of criticism from artists and curators who described the withdrawal of the video as "censorship and banishment of queer, sexual, feminist and Latinx creative expression," as well as "an act of discrimination and flagrant homophobia," according to the organizers of 'XicanX' on networks.

The issue was so high profile that even the National Coalition Against Censorship (NCAC), a non-profit organization that seeks to defend freedom of expression, had to intervene. Last week, NCAC wrote a letter to San Antonio Mayor Ron Nirenberg, stating that the removal of the video is a direct attack on the First Amendment of the Constitution.

The NCAC still went one step further and argued that the city's Department of Culture's definition of "obscenity" is "illegal," as it collides head-on with the historic 1973 case of Miller v. California. According to the so-called Miller Test, no material with literary, artistic, political or scientific value can be classified as 'obscene.'

"Although the work has a sexual content - as is the case with many contemporary artworks - it certainly does not meet the definition of obscenity held in Miller v. California," the NCAC letter notes. "By removing Ibarra's work from the exhibition at the Arts Center, the city of San Antonio is probably violating the artist's rights of free expression and exposing the city to both bad publicity and legal liability.

Master of provocation

A native of Oklahoma but of Mexican descent, Xandra Ibarra does keep one promise: not to leave us indifferent. In most of her works, as in her latest series of sculptures 'Kill your darlings,'she confronts us with monstrosity, the taboos that surround us and the notion of identity as a construct that can be as dangerous as a plague.

"I make work that brings me joy and I enjoy threatening the grip that prescriptive nationalist discourses and their signifiers have on me whether they be Chicano, American, Native and/or Mexican," Ibarra states. The roots are like the pea plant to her, strangling while allowing what has been sown to grow, allowing a piece of work to bear fruit.

Can you fight prejudice through art, break it down once and for all? I ask her one of those questions to which one expects a hopeful answer.

"Stereotypes don't die, they are eternally in a cycle of renewal," she replies. And judging by the silence of the San Antonio government, that answer that sees no way out is like life, a set of chained obstacles to be overcome.

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Apple may be forced to disclose censorship requests from China – The Guardian

Posted: at 1:47 am

Apple could be forced to disclose details of censorship requests from China and other nations after two major shareholder groups backed a proposal that would force the tech firm to make new human rights commitments.

The motion, set to be voted on by the companys investors on Wednesday, was prompted by numerous allegations of Apple kowtowing to Beijing and blocking apps from being used by Chinese customers.

If approved by investors, the scheme could have implications beyond China and potentially expose details of tensions between Apple and other jurisdictions. The California-headquartered tech giant has regularly clashed with the US government, including most prominently over requests for iPhones to be unlocked.

The human rights resolution was put forward by campaign group SumOfUs, which cited several concerns about Apples relationship with the Chinese state in its submission to investors.

Apple failed in an attempt to block the vote from taking place. And now the Guardian has learned that the proposal has the support of the influential corporate governance groups ISS and Glass Lewis.

Together these two firms advise the worlds largest institutional investors on how they vote at companys annual meetings, so their backing for the proposal is a coup for SumOfUs.

Ahead of Wednesdays annual meeting, ISS and Glass Lewis have sent reports to their clients, seen by the Guardian, explaining why they should back the proposal.

Glass Lewis said: [W]e believe that it would be prudent for the company to exhibit enhanced transparency around how it respects the right to free expression.

In their reports, both Glass Lewis and ISS highlighted various news reports of Apple making apps unavailable in China.

In 2016, it emerged that Apple had removed its iBooks Store and iTunes Movies services from devices owned by Chinese customers. In 2017, it removed several virtual private network (VPN) apps, which were used by Chinese citizens to bypass state censorship apparatus. And last year the company removed HKMap.Live, a controversial crowdsourced mapping app that was being used by Hong Kong protesters to track police activity.

The SumOfUs proposal would force Apples board to prepare an annual report on the companys policies relating to freedom of expression and access to information. The board would be compelled to state in the report whether they are publicly committed to freedom of expression and access to information.

They would also have to disclose a description of the actions Apple has taken in the past year in response to government or third-party demands that were reasonably likely to limit free expression or access to information.

SumOfUs believes the need to clarify Apples relationship with China is made particularly urgent by public outrage surrounding Beijings treatment of Uighur people sent to internment camps and pro-democracy protesters in Hong Kong.

Despite backing from ISS and Glass Lewis, SumOfUs still faces an uphill battle to pass the motion because it is opposed by Apples board, which includes the companys chief executive, Tim Cook, and former US vice-president Al Gore.

Apple has issued a statement saying the proposal is unnecessary based on the extensive information that is already publicly provided to our shareholders and users.

The company currently publishes transparency data disclosing the number of government requests it receives by country for customer data and app removal.

For instance, Apple reported that between January and June last year, 288 apps were removed in mainland China for legal or platform violation. Apple stated that the majority of these requests related to pornography, illegal content and gambling.

But in its report to investors, ISS noted that the quantitative approach to the companys transparency report provides little context for the app removal requests from the Chinese government or explanation of the risks that may be involved.

Apple said in its statement that free expression is central to our company and its success but that it is obliged to comply with local laws and to protect the safety of our customers and employees, including by removing apps.

The company said: [W]hile we may disagree with certain decisions at times, we do not believe it would be in the best interests of our users to simply abandon markets, which would leave consumers with fewer choices and fewer privacy protections.

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A proposal could force Apple to disclose alleged censorship actions – PhoneArena

Posted: at 1:47 am

Apple has always been keen on protecting its users privacy, as well as its own. However, The Guardian is reporting today that Apple might be forced to disclose information related to Chinese censorship requests.Apparently, there has been a proposal by campaign group SumOfUs, asking Apple to provide information in regards to its relationship with the Chinese government and the resulting censorship of Chinese customers. Concerns include Apple blocking certain apps from usage by Chinese customers or obstructing the Chinese peoples right of free expression.

Now, two influential corporate governance groups have backed up the proposal - Glass Lewis and ISS. They state that Apple should be more transparent in regards to the right of free expression.

The proposal would force Apple to provide an annual report of the companys censorship policies as well as a description of all the actions it took that could be considered limiting to free expression or obstructing access to information in response to government or third-party demands for the past year.

In opposition to SumOfUs stands the Apple board, including the company's CEO, Tim Cook, as well as former US vice-president Al Gore. Apple believes it has already provided enough information to its shareholders and users, giving as an example its report of the removal of 288 apps in the first half of last year, for legal violations. Most of them were related to illegal activities or content.

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